3,295 results match your criteria Bioinspired Biomimetic And Nanobiomaterials[Journal]


Thermal insulation design bioinspired by microstructure study of penguin feather and polar bear hair.

Acta Biomater 2019 Apr 18. Epub 2019 Apr 18.

International Centre of Electron Microscopy for Materials Science, Faculty of Metals Engineering and Industrial Computer Science, AGH University of Science and Technology, Poland; AGH University of Science and Technology, Al. A. Mickiewicza 30, 30-059 Kraków, Poland. Electronic address:

Nature is an amazing source of inspiration for the design of thermal insulation strategies, which are key for saving energy. In nature, thermal insulation structures, such as penguin feather and polar bear hair, are well developed; enabling the animals' survival in frigid waters. The detailed microscopy investigations conducted in this study, allowed us to perform microstructural analysis of these thermally insulating materials, including statistical measurements of keratin fiber and pore dimensions directly from high resolution Scanning Electron Microscope (SEM) images. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.04.031DOI Listing

Real-Time Classification of Multivariate Olfaction Data Using Spiking Neural Networks.

Sensors (Basel) 2019 Apr 18;19(8). Epub 2019 Apr 18.

School of Engineering, Edith Cowan University, Perth 6027, Australia.

Recent studies in bioinspired artificial olfaction, especially those detailing the application of spike-based neuromorphic methods, have led to promising developments towards overcoming the limitations of traditional approaches, such as complexity in handling multivariate data, computational and power requirements, poor accuracy, and substantial delay for processing and classification of odors. Rank-order-based olfactory systems provide an interesting approach for detection of target gases by encoding multi-variate data generated by artificial olfactory systems into temporal signatures. However, the utilization of traditional pattern-matching methods and unpredictable shuffling of spikes in the rank-order impedes the performance of the system. Read More

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http://dx.doi.org/10.3390/s19081841DOI Listing
April 2019
2 Reads

Influence of Axial Length on Parafoveal and Peripapillary Metrics from Swept Source Optical Coherence Tomography Angiography.

Curr Eye Res 2019 Apr 17. Epub 2019 Apr 17.

a Department of Ophthalmology , 1st affiliated hospital of Xi'an Jiaotong University , Xi'an , Shaanxi , China .

Purpose: To assess the effect of axial length (AL) on the quantification of superficial vessel density of both macular and disc region using swept source optical coherence tomography angiography (SSOCTA).

Methods: This is a cross-sectional clinical study. Seventy-five eyes from 75 Chinese healthy participants (56 females) with a mean age of 26. Read More

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http://dx.doi.org/10.1080/02713683.2019.1607393DOI Listing

Composite nanostructures and adhesion analysis of natural plant hydrogels investigated by atomic force microscopy.

IEEE Trans Nanobioscience 2019 Apr 12. Epub 2019 Apr 12.

Hydrogels designed by biomimetism and bioinspiration have been considered as a promising biomaterial for biomedical applications due to their biocompatible characteristics. Though biomimetic or bioinspired hydrogels have been widely studied by biochemical analysis, so far the detailed organizations and properties of native natural hydrogels are still not fully understood. The advent of atomic force microscopy (AFM) provides a potent tool for probing the biological samples in their living states with nanometer spatial resolution, which offers new possibilities for addressing the biological and material issues at the nanoscale. Read More

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http://dx.doi.org/10.1109/TNB.2019.2911044DOI Listing
April 2019
1 Read

Information Transmitted From Bioinspired Neuron-Astrocyte Network Improves Cortical Spiking Network's Pattern Recognition Performance.

IEEE Trans Neural Netw Learn Syst 2019 Apr 11. Epub 2019 Apr 11.

We trained two spiking neural networks (SNNs), the cortical spiking network (CSN) and the cortical neuron-astrocyte network (CNAN), using a spike-based unsupervised method, on the MNIST and alpha-digit data sets and achieve an accuracy of 96.1% and 77.35%, respectively. Read More

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http://dx.doi.org/10.1109/TNNLS.2019.2905003DOI Listing
April 2019
1 Read

Bioinspired superoleophobic/superhydrophilic functionalized cotton for efficient separation of immiscible oil-water mixtures and oil-water emulsions.

J Colloid Interface Sci 2019 Apr 11;548:123-130. Epub 2019 Apr 11.

Key Laboratory of Micro-Systems and Micro-Structures Manufacturing, Ministry of Education and School of Mechatronics Engineering, Harbin Institute of Technology, Xidazhi, 92, Harbin 150001, PR China.

Oil contamination is pressing environmental and natural resource issues. Oil-water separation technology can be used for water purification. Traditional methods are either time consuming or energy intensive. Read More

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http://dx.doi.org/10.1016/j.jcis.2019.04.031DOI Listing

Current Status and Perspectives of Human Mesenchymal Stem Cell Therapy.

Stem Cells Int 2019 7;2019:4762634. Epub 2019 Mar 7.

Tissue Engineering Group (TEG), National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya, Lembah Pantai, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2019/4762634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431493PMC

Highly Stretchable and Transparent Double-Network Hydrogel Ionic Conductor as Flexible Thermal-Mechanical Dual Sensors and Electroluminescent Devices.

ACS Appl Mater Interfaces 2019 Apr 15. Epub 2019 Apr 15.

The latest generation flexible devices feature materials as conductive, highly stretchable and transparent to meet the requirements of a reliable performance. However, the existing conductors are mostly electronic conductors which can't satisfy these high performance challenges. A robust hydrogel ionic conductor was rapidly fabricated with facile one-pot approach by employing bioinspired agar with physically crosslinked network, polyacrylamide (PAM) with photoinitiated crosslinked network under appropriate UV intensity and Li+ as conductive ions. Read More

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http://dx.doi.org/10.1021/acsami.9b01989DOI Listing

Multi-dimensional bioinspired tactics using an engineered mussel protein glue-based nanofiber conduit for accelerated functional nerve regeneration.

Acta Biomater 2019 Apr 9. Epub 2019 Apr 9.

Department of Chemical Engineering, Pohang University of Science and Technology, Pohang 37673, Republic of Korea. Electronic address:

Limited regenerative capacity of the nervous system makes treating traumatic nerve injuries with conventional polymer-based nerve grafting a challenging task. Consequently, utilizing natural polymers and biomimetic topologies became obvious strategies for nerve conduit designs. As a bioinspired natural polymer from a marine organism, mussel adhesive proteins (MAPs) fused with biofunctional peptides from extracellular matrix (ECM) were engineered for accelerated nerve regeneration by enhancing cell adhesion, proliferation, neural differentiation, and neurite formation. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.04.018DOI Listing

Bioinspired and Biomimetic Nanomedicines.

Acc Chem Res 2019 Apr 12. Epub 2019 Apr 12.

Department of Bioengineering , University of California , Los Angeles , California 90095 , United States.

Nanomedicine development aims to enhance the efficacy, accuracy, safety, and/or compliance of diagnosis and treatment of diseases by leveraging the unique properties of engineered nanomaterials. To this end, a multitude of organic and inorganic nanoparticles have been designed to facilitate drug delivery, sensing, and imaging, some of which are currently in clinical trials or have been approved by the Food and Drug Administration (FDA). In the process, the increasing knowledge in understanding how natural particulates, including cells, pathogens, and organelles, interact with body and cellular systems has spurred efforts to mimic their morphology and functions for developing new generations of nanomedicine formulations. Read More

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http://pubs.acs.org/doi/10.1021/acs.accounts.9b00079
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http://dx.doi.org/10.1021/acs.accounts.9b00079DOI Listing
April 2019
6 Reads

Electrically assisted 3D printing of nacre-inspired structures with self-sensing capability.

Sci Adv 2019 Apr 5;5(4):eaau9490. Epub 2019 Apr 5.

Epstein Department of Industrial and Systems Engineering, University of Southern California, 3715 McClintock Ave., Los Angeles, CA 90089, USA.

Lightweight and strong structural materials attract much attention due to their strategic applications in sports, transportation, aerospace, and biomedical industries. Nacre exhibits high strength and toughness from the brick-and-mortar-like structure. Here, we present a route to build nacre-inspired hierarchical structures with complex three-dimensional (3D) shapes by electrically assisted 3D printing. Read More

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http://dx.doi.org/10.1126/sciadv.aau9490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450688PMC

Electrospin-Coating of Paper: A Natural Extracellular Matrix Inspired Design of Scaffold.

Polymers (Basel) 2019 Apr 9;11(4). Epub 2019 Apr 9.

Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia.

Paper has recently found widespread applications in biomedical fields, especially as an alternative scaffolding material for cell cultures, owing to properties such as its fibrous nature, porosity and flexibility. However, paper on its own is not an optimal material for cell cultures as it lacks adhesion moieties specific to mammalian cells, and modifications such as hydrogel integration and chemical vapor deposition are necessary to make it a favorable scaffolding material. The present study focuses on modification of filter paper through electrospin-coating and dip-coating with polycaprolactone (PCL), a promising biomaterial in tissue engineering. Read More

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http://dx.doi.org/10.3390/polym11040650DOI Listing

Learning bioinspired joint geometry from motion capture data of bat flight.

Bioinspir Biomim 2019 Apr 10;14(3):036013. Epub 2019 Apr 10.

Department of Mechanical Engineering, Virginia Tech, Blacksburg, Virginia 24060, United states of America. Author to whom all correspondence should be addressed.

Bioinspired robotic systems are often designed by assuming that the kinematics of the biological system of interest are well approximated by an open kinematic chain subject to box constraints. These box-constrains are typically generated by designer interpretation of biomotion and anatomical studies or pragmatic fabrication constraints. In contrast to this standard design paradigm, this paper presents a methodology for learning joint geometry which restricts the range of motion of generic ball joints to only the reachable set observed during biomotion experiments. Read More

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http://dx.doi.org/10.1088/1748-3190/ab0fbaDOI Listing

Bioinspired Polymeric Helical and Superhelical Microfibers via Microfluidic Spinning.

Macromol Rapid Commun 2019 Apr 10:e1900111. Epub 2019 Apr 10.

Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, State-Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China.

The helix and superhelix play critical roles in the achievement of tissue functions. These fascinating structures have attracted increasing interest due to their potential biomimicking applications. However, continuous and controlled fabrication of these structures, especially the superhelical structures, from various polymers for different practical applications still remains a big challenge. Read More

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http://dx.doi.org/10.1002/marc.201900111DOI Listing

Lessons from nature for green science and technology: an overview and bioinspired superliquiphobic/philic surfaces.

Authors:
Bharat Bhushan

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180274

Nanoprobe Laboratory for Bio- and Nanotechnology and Biomimetics, The Ohio State University , Columbus, OH 43210-1142 , USA.

Nature has developed materials, objects and processes that function from the macroscale to the nanoscale. The emerging field of biomimetics allows one to mimic biology or nature to develop nanomaterials, nanodevices and processes which provide desirable properties. The biologically inspired materials and structured surfaces are being explored for various commercial applications. Read More

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http://www.royalsocietypublishing.org/doi/10.1098/rsta.2018.
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http://dx.doi.org/10.1098/rsta.2018.0274DOI Listing
February 2019
4 Reads

Re-designing materials for biomedical applications: from biomimicry to nature-inspired chemical engineering.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180268

1 Centre for Nature Inspired Engineering, Department of Chemical Engineering, University College London , Torrington Place, London WC1E 7JE , UK.

Gathering inspiration from nature for the design of new materials, products and processes is a topic gaining rapid interest among scientists and engineers. In this review, we introduce the concept of nature-inspired chemical engineering (NICE). We critically examine how this approach offers advantages over straightforward biomimicry and distinguishes itself from bio-integrated design, as a systematic methodology to present innovative solutions to challenging problems. Read More

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http://dx.doi.org/10.1098/rsta.2018.0268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335285PMC
February 2019

Design of surfaces for controlling hard and soft fouling.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180266

1 Department of Materials Science and Engineering, University of Michigan , Ann Arbor, MI 48109 , USA.

In this review, we present a framework to guide the design of surfaces which are resistant to solid fouling, based on the modulus and length scale of the fouling material. Solid fouling is defined as the undesired attachment of solid contaminants including ice, clathrates, waxes, inorganic scale, polymers, proteins, dust and biological materials. We first provide an overview of the surface design approaches typically applied across the scope of solid fouling and explain how these disparate research efforts can be united to an extent under a single framework. Read More

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http://dx.doi.org/10.1098/rsta.2018.0266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335287PMC
February 2019

Physics of pre-wetted, lubricated and impregnated surfaces: a review.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180264

Engineering Faculty, Chemical Engineering, Biotechnology and Materials Department, Ariel University , PO Box 3, 407000 Ariel , Israel.

Wetting phenomena occurring on pre-wetted flat and rough solid surfaces are reviewed. The wetting of lubricated flat surfaces is strongly correlated with the tribological properties of a solid/lubricant pair. The phenomena taking place on micro- and nano-rough oil-impregnated surfaces have attracted the attention of the scientific community due to their numerous promising applications as omniphobic, self-healing, anti-icing and anti-bacterial interfaces. Read More

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http://dx.doi.org/10.1098/rsta.2018.0264DOI Listing
February 2019

Bioinspired materials and surfaces for green science and technology.

Authors:
Bharat Bhushan

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180336

Ohio Eminent Scholar and The Howard D. Winbigler Professor, Nanoprobe Laboratory for Bio and Nanotechnology and Biomimetics (NLBB)m, The Ohio State University , Columbus, OH , USA.

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http://dx.doi.org/10.1098/rsta.2018.0336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335288PMC
February 2019

Bionics and green technology in maritime shipping: an assessment of the effect of Salvinia air-layer hull coatings for drag and fuel reduction.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180263

1 Nees Institute for Biodiversity of Plants, University of Bonn , Venusbergweg 22, D-53115 Bonn , Germany.

To save energy and reduce environmental impacts, new technologies towards a development of a sustainable 'greener' economy are needed. The main opportunity to improve sustainability by reducing emissions is within the transport sector. More than 90% of all goods worldwide are transported by ships. Read More

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http://www.royalsocietypublishing.org/doi/10.1098/rsta.2018.
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http://dx.doi.org/10.1098/rsta.2018.0263DOI Listing
February 2019
3 Reads

Water condensation and transport on bioinspired triangular patterns with heterogeneous wettability at a low temperature.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180335

Nanoprobe Laboratory for Bio and Nanotechnology and Biomimetics (NLBB), The Ohio State University , 201 West 19th Avenue, Columbus, OH 43210-1142 , USA.

Desert beetles and cactus plants collect water from fog in arid regions. The desert beetle uses heterogeneous wettability to transport water to its mouth. A cactus uses conical spines which provide Laplace pressure gradient to transport water to its base. Read More

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http://dx.doi.org/10.1098/rsta.2018.0335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335283PMC
February 2019

Fabrication of bioinspired, self-cleaning, anti-icing, superliquiphilic/phobic titanium using different pathways.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180273

Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics (NLBB), The Ohio State University , 201 West 19th Avenue, Columbus, OH 43210-1142 , USA.

Titanium is an important material having a high tensile strength-to-density ratio and high corrosion resistance. It has found applications in the aerospace, marine, automotive and biomedical industries. In some of the applications, it is important to have it as a highly liquid repellent, anti-icing and self-cleaning. Read More

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http://dx.doi.org/10.1098/rsta.2018.0273DOI Listing
February 2019

Facile approach to develop anti-corrosive superhydrophobic aluminium with high mechanical, chemical and thermal durability.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180272

2 Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics, The Ohio State University , Columbus, OH 43210 , USA.

Durable, superhydrophobic and self-cleaning aluminium surfaces with high corrosion resistance are desirable in many industrial applications. In this study, a facile approach is used to produce aluminium surfaces with superhydrophobicity with a low tilt angle by creating desired roughness structure by immersing in NaOH solution followed by lowering the surface energy by immersing in hexadecyltrimethoxysilane solution. The coated samples show water contact angle of 164 ± 7° and tilt angle of 5 ± 1°. Read More

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http://dx.doi.org/10.1098/rsta.2018.0272DOI Listing
February 2019

Structural properties and their influence on the prey retention in the spider web.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180271

2 Nanoprobe Laboratory for Bio- and Nanotechnology and Biomimetics (NLB2), The Ohio State University , 201 W. 19th Avenue, Columbus, OH 43210-1142 , USA.

Orb webs absorb the impact energy of prey and transmit vibratory information to the spider with minimal structural damage. The structural properties of the web and the arrangement of threads within the web affect transmission time during the prey impact. The objective of the present study is to determine damping, stiffness, and transmissibility of healthy and damaged spider webs. Read More

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http://dx.doi.org/10.1098/rsta.2018.0271DOI Listing
February 2019
2.864 Impact Factor

Designing liquid repellent, icephobic and self-cleaning surfaces with high mechanical and chemical durability.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180270

Nanoprobe Laboratory for Bio and Nanotechnology and Biomimetics (NLBB), Ohio State University , 201 W. 19th Avenue, Columbus, OH 43210-1142 , USA.

Liquid repellent, icephobic and self-cleaning surfaces are of interest in industrial applications, including solar panels, self-cleaning windows, wind turbines, and automotive and aerospace components. In this study, a coating using a simple and scalable fabrication technique was used to produce superliquiphobic surfaces with a low tilt angle. The coating comprises hydrophobic SiO nanoparticles with a binder of methylphenyl silicone resin to achieve superhydrophobicity. Read More

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http://dx.doi.org/10.1098/rsta.2018.0270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335286PMC
February 2019

Designing bioinspired surfaces for water collection from fog.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180269

Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics (NLBB), The Ohio State University , 201 W. 19th Avenue, Columbus, OH 43210-1142 , USA.

A systematic study is presented on various water collectors, bioinspired by desert beetles, desert grass and cacti. Three water collecting mechanisms including heterogeneous wettability, grooved surfaces, and Laplace pressure gradient, were investigated on flat, cylindrical, conical surfaces, and conical array. It is found that higher water repellency in flat surfaces results in higher water collection rate and inclination angle (with respect to the vertical axis) has little effect. Read More

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http://dx.doi.org/10.1098/rsta.2018.0269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335284PMC
February 2019

Transparency in the eye region of an ostracod carapace ( Macrocypridina castanea, Myodocopida).

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180267

2 Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University , Maindy Road, Cardiff , UK.

Many myodocopid ostracods are unusual in that they have well-developed compound eyes yet must view their environment through a shell. The cypridinid Macrocypridina castanea is relatively large among ostracods (about 5-10 mm) and is a pelagic predator. This species possess highly pigmented shells with a transparent region lying just above the eye. Read More

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http://dx.doi.org/10.1098/rsta.2018.0267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335281PMC
February 2019

Replicating the complexity of natural surfaces: technique validation and applications for biomimetics, ecology and evolution.

Philos Trans A Math Phys Eng Sci 2019 Feb;377(2138):20180265

1 Institut Charles Sadron, CNRS UPR022, Université de Strasbourg , Strasbourg , France.

The surfaces of animals, plants and abiotic structures are not only important for organismal survival, but they have also inspired countless biomimetic and industrial applications. Additionally, the surfaces of animals and plants exhibit an unprecedented level of diversity, and animals often move on the surface of plants. Replicating these surfaces offers a number of advantages, such as preserving a surface that is likely to degrade over time, controlling for non-structural aspects of surfaces, such as compliance and chemistry, and being able to produce large areas of a small surface. Read More

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http://dx.doi.org/10.1098/rsta.2018.0265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335282PMC
February 2019

Modulation of the Catalytic Properties of Lipase B from by Immobilization on Tailor-Made Magnetic Iron Oxide Nanoparticles: The Key Role of Nanocarrier Surface Engineering.

Polymers (Basel) 2018 Jun 5;10(6). Epub 2018 Jun 5.

Department of Biomaterials and Bioinspired Material, Materials Science Institute of Madrid (ICMM-CSIC), Sor Juana Inés de la Cruz 3, Cantoblanco, 28049 Madrid, Spain.

The immobilization of biocatalysts on magnetic nanomaterial surface is a very attractive alternative to achieve enzyme nanoderivatives with highly improved properties. The combination between the careful tailoring of nanocarrier surfaces and the site-specific chemical modification of biomacromolecules is a crucial parameter to finely modulate the catalytic behavior of the biocatalyst. In this work, a useful strategy to immobilize chemically aminated lipase B from on magnetic iron oxide nanoparticles (IONPs) by covalent multipoint attachment or hydrophobic physical adsorption upon previous tailored engineering of nanocarriers with poly-carboxylic groups (citric acid or succinic anhydride, CALB@CA-NPs and CALB@SA-NPs respectively) or hydrophobic layer (oleic acid, CALB@OA-NPs) is described. Read More

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http://dx.doi.org/10.3390/polym10060615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404122PMC

Bioinspired Fabrication of Polyurethane/Regenerated Silk Fibroin Composite Fibres with Tubuliform Silk-Like Flat Stress⁻Strain Behaviour.

Polymers (Basel) 2018 Mar 19;10(3). Epub 2018 Mar 19.

Institute of Textiles & Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon 999077, Hong Kong, China.

Tubuliform silk is one of the seven different types of spider silks, which is well known for its unique tensile behaviour with Flat Tensile Stress⁻Strain (FTSS) curve. It is found that anisotropic microstructure of β-sheets is responsible for this property. In recent years, bioinspired approaches to engineer fibres supported by modern manufacturing systems have been attracting considerable interest. Read More

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http://dx.doi.org/10.3390/polym10030333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414937PMC

Nature-Inspired Green Procedure for Improving Performance of Protein-Based Nanocomposites via Introduction of Nanofibrillated Cellulose-Stablized Graphene/Carbon Nanotubes Hybrid.

Polymers (Basel) 2018 Mar 6;10(3). Epub 2018 Mar 6.

Key Laboratory of Wood Materials Science and Utilization, Beijing Forestry University, Ministry of Education, Beijing 100083, China.

Soy protein isolate (SPI) provides a potential alternative biopolymer source to fossil fuels, but improving the mechanical properties and water resistance of SPI composites remains a huge challenge. Inspired by the synergistic effect of natural nacre, we developed a novel approach to fabricate high-performance SPI nanocomposite films based on 2D graphene (G) nanosheets and 1D carbon nanotubes (CNTs) and nanofibrillated cellulose (NFC) using a casting method. The introduction of web-like NFC promoted the uniform dispersion of graphene/CNTs in the biopolymer matrix, as well as a high extent of cross-linkage combination between the fillers and SPI matrix. Read More

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http://www.mdpi.com/2073-4360/10/3/270
Publisher Site
http://dx.doi.org/10.3390/polym10030270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415091PMC
March 2018
4 Reads

Pursuing Specific Chemotherapy of Orthotopic Breast Cancer with Lung Metastasis from Docking Nanoparticles Driven by Bioinspired Exosomes.

Nano Lett 2019 Apr 15. Epub 2019 Apr 15.

School of Biomedical Engineering, State Key Laboratory of Oncology in South China , Sun Yat-sen University , Guangzhou , Guangdong 510006 , China.

Breast cancer develops from local tissue but is characterized by a distinct metastatic pattern involving regional lymph nodes and distant organs, which is the primary cause of high mortality in breast cancer patients. Herein, optimal docking nanoparticles (NPs) composed of a laurate-functionalized Pt(IV) prodrug (Pt(lau)), human serum albumin (HSA), and lecithin were predicted by computational modeling, prepared by nanoprecipitation, and validated by fluorescence spectroscopy. As macrophages have been reported to be preferentially recruited by breast cancer, Rex, the exosome spontaneously secreted by murine RAW 264. Read More

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http://dx.doi.org/10.1021/acs.nanolett.9b00824DOI Listing
April 2019
1 Read

Novel Pathway for Efficient Covalent Modification of Polyester Materials of Different Design to Prepare Biomimetic Surfaces.

Polymers (Basel) 2018 Nov 23;10(12). Epub 2018 Nov 23.

Institute of Chemistry, Saint-Petersburg State University, St. Petersburg 199034, Russia.

To form modern materials with biomimic surfaces, the novel pathway for surface functionalization with specific ligands of well-known and widely used polyester-based rigid media was developed and optimized. Two types of material bases, namely, poly(lactic acid) and poly(ε-caprolactone), as well as two types of material design, e.g. Read More

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http://www.mdpi.com/2073-4360/10/12/1299
Publisher Site
http://dx.doi.org/10.3390/polym10121299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401704PMC
November 2018
2 Reads

Bioinspired Engineering towards Tailoring Advanced Lignin/Rubber Elastomers.

Polymers (Basel) 2018 Sep 18;10(9). Epub 2018 Sep 18.

School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.

The pursuit of high volume and high value-added applications for lignin has been a long-term challenge. In this work, inspired by the energy sacrificial mechanism from biological materials, we developed high-performance lignin/carbon black (CB)/nitrile rubber (NBR) elastomers by constructing a dual-crosslinking network consisting of sulfur covalent bonds and dynamic coordination sacrificial bonds. Lignin was not only used for the substitution of half mass of CB in the NBR elastomer but also served as natural ligands for the Zn-based coordination bonds, providing a significant synergistic coordination enhancement effect. Read More

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http://dx.doi.org/10.3390/polym10091033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403759PMC
September 2018

Unravelling hagfish slime.

J R Soc Interface 2019 Jan;16(150):20180710

2 Department of Mathematics, University of Wisconsin , Madison, WI , USA.

Hagfish slime is a unique predator defence material containing a network of long fibrous threads each ∼10 cm in length. Hagfish release the threads in a condensed coiled state known as skeins (∼100 µm), which must unravel within a fraction of a second to thwart a predator attack. Here we consider the hypothesis that viscous hydrodynamics can be responsible for this rapid unravelling, as opposed to chemical reaction kinetics alone. Read More

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http://dx.doi.org/10.1098/rsif.2018.0710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364663PMC
January 2019

Electrochemical triggering of lipid bilayer lift-off oscillation at the electrode interface.

J R Soc Interface 2019 Jan;16(150):20180626

ITMO University , 9 Lomonosova Street, St Petersburg 191002 , Russian Federation.

In situ studies of transmembrane channels often require a model bioinspired artificial lipid bilayer (LB) decoupled from its underlaying support. Obtaining free-standing lipid membranes is still a challenge. In this study, we suggest an electrochemical approach for LB separation from its solid support via hydroquinone oxidation. Read More

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http://dx.doi.org/10.1098/rsif.2018.0626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364645PMC
January 2019

Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment.

J R Soc Interface 2019 Jan;16(150):20180675

1 Department of Mechanical and Aerospace Engineering, University of California San Diego , San Diego, CA , USA.

Schistosomiasis is a chronic and morbid disease of poverty affecting approximately 200 million people worldwide. Mature schistosome flatworms wander in the host's hepatic portal and mesenteric venous system where they encounter a range of blood flow conditions and geometrical confinement. However, the mechanisms that support schistosome locomotion and underlie the pathogen's adaptation to its physical environment are largely unknown. Read More

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http://dx.doi.org/10.1098/rsif.2018.0675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364656PMC
January 2019

Interfibril hydrogen bonding improves the strain-rate response of natural armour.

J R Soc Interface 2019 Jan;16(150):20180775

4 School of Engineering, Universidad EAFIT , Medellín , Colombia.

Fish scales are laminated composites that consist of plies of unidirectional collagen fibrils with twisted-plywood stacking arrangement. Owing to their composition, the toughness of scales is dependent on the intermolecular bonding within and between the collagen fibrils. Adjusting the extent of this bonding with an appropriate stimulus has implications for the design of next-generation bioinspired flexible armours. Read More

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http://dx.doi.org/10.1098/rsif.2018.0775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364658PMC
January 2019

Plasma-generated reactive oxygen and nitrogen species can lead to closure, locking and constriction of the Dionaea muscipula Ellis trap.

J R Soc Interface 2019 Jan;16(150):20180713

3 The Center for Space Plasma and Aeronomic Research, The University of Alabama in Huntsville , Huntsville, AL 35899 , USA.

Reactive oxygen and nitrogen species (RONS) can influence plant signalling, physiology and development. We have previously observed that an argon plasma jet in atmospheric air can activate plant movements and morphing structures in the Venus flytrap and Mimosa pudica similar to stimulation of their mechanosensors in vivo. In this paper, we found that the Venus flytrap can be activated by plasma jets without direct contact of plasma with the lobe, midrib or cilia. Read More

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http://dx.doi.org/10.1098/rsif.2018.0713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364641PMC
January 2019

Emerging Trends in Information-Driven Engineering of Complex Biological Systems.

Adv Mater 2019 Apr 8:e1806898. Epub 2019 Apr 8.

Institute of Functional Interfaces (IFG), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.

Synthetic biological systems are used for a myriad of applications, including tissue engineered constructs for in vivo use and microengineered devices for in vitro testing. Recent advances in engineering complex biological systems have been fueled by opportunities arising from the combination of bioinspired materials with biological and computational tools. Driven by the availability of large datasets in the "omics" era of biology, the design of the next generation of tissue equivalents will have to integrate information from single-cell behavior to whole organ architecture. Read More

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http://dx.doi.org/10.1002/adma.201806898DOI Listing

Highly Stretchable, Adaptable, and Durable Strain Sensing Based on a Bioinspired Dynamically Cross-Linked Graphene/Polymer Composite.

Small 2019 Apr 8:e1900848. Epub 2019 Apr 8.

State Key Laboratory of New Ceramics and Fine Processing and Center for Nano and Micro Mechanics, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.

Flexible strain sensors can detect physical signals (e.g., temperature, humidity, and flow) by sensing electrical deviation under dynamic deformation, and they have been used in diverse fields such as human motion detection, medical care, speech recognition, and robotics. Read More

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http://dx.doi.org/10.1002/smll.201900848DOI Listing
April 2019
1 Read

Oriented collagen fiber membranes formed through counter-rotating extrusion and their application in tendon regeneration.

Biomaterials 2019 Jul 29;207:61-75. Epub 2019 Mar 29.

Lab for Smart & Bioinspired Materials, College of Bioengineering, Chongqing University, Chongqing, 400030, China; Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Chongqing, 400030, China. Electronic address:

Well-aligned collagen fiber scaffolds are considered promising candidates for tendon tissue engineering in terms of their biomimetic chemical composition and topographic structure. Insoluble collagen fibers are more suitable for the preparation of scaffolds than soluble collagens due to their more approximate self-assembly and mechanical properties to native collagen ECMs. In this work, we employed counter-rotating extrusion technology for the first time to fabricate an aligned (CM, orientation angle 0°-15°) and a randomly-oriented (CM, orientation angle -60°-60°) collagen membrane from insoluble collagens. Read More

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http://dx.doi.org/10.1016/j.biomaterials.2019.03.041DOI Listing
July 2019
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A bioinspired in vitro bioelectronic tongue with human T2R38 receptor for high-specificity detection of N-C=S-containing compounds.

Talanta 2019 Jul 6;199:131-139. Epub 2019 Feb 6.

Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China; State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai 200050, China. Electronic address:

Detection and identification of bitter compounds draw great attention in pharmaceutical and food industry. Several well-known agonists of specific bitter taste receptors have been found to exhibit anti-cancer effects. For example, N-C=S-containing compounds, such as allyl-isothiocyanates, have shown cancer chemo-preventive effects. Read More

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http://dx.doi.org/10.1016/j.talanta.2019.02.021DOI Listing
July 2019
1 Read

Bacterially Produced, Nacre-Inspired Composite Materials.

Small 2019 Apr 5:e1805312. Epub 2019 Apr 5.

Department of Biology, University of Rochester, Hutchison Road, Rochester, NY, 14620, USA.

The impressive mechanical properties of natural composites, such as nacre, arise from their multiscale hierarchical structures, which span from nano- to macroscale and lead to effective energy dissipation. While some synthetic bioinspired materials have achieved the toughness of natural nacre, current production methods are complex and typically involve toxic chemicals, extreme temperatures, and/or high pressures. Here, the exclusive use of bacteria to produce nacre-inspired layered calcium carbonate-polyglutamate composite materials that reach and exceed the toughness of natural nacre, while additionally exhibiting high extensibility and maintaining high stiffness, is introduced. Read More

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http://dx.doi.org/10.1002/smll.201805312DOI Listing

Tandem Catalysis with Antagonistic Catalysts Compartmentalized in the Dispersed and Continuous Phases of a Pickering Emulsion.

ChemSusChem 2019 Apr 4. Epub 2019 Apr 4.

Inorganic Chemistry and Catalysis, Debye Institute for Nanomaterials Science, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.

Tandem catalysis combines multiple conversion steps, catalysts, and reagents in one reaction medium, offering the potential to reduce waste and time. In this study, Pickering emulsions-emulsions stabilized by solid particles-are used as easy-to-prepare and bioinspired, compartmentalized reaction media for tandem catalysis. Making use of simple and inexpensive acid and base catalysts, the strategy of compartmentalization of two noncompatible catalysts in both phases of the emulsion is demonstrated by using the deacetalization-Knoevenagel condensation reaction of benzaldehyde dimethyl acetal as a probe reaction. Read More

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http://dx.doi.org/10.1002/cssc.201900279DOI Listing
April 2019
2 Reads

Artificial Signal Feedback Network Mimicking Cellular Adaptivity.

J Am Chem Soc 2019 Apr 16. Epub 2019 Apr 16.

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province , Hunan University , Changsha Hunan , 410082 , China.

Inspired by this elegant system of cellular adaptivity, we herein report the rational design of a dynamic artificial adaptive system able to sense and respond to environmental stresses in a unique sense-and-respond mode. Utilizing DNA nanotechnology, we constructed an artificial signal feedback network and anchored it to the surface membrane of a model giant membrane vesicle (GMV) protocell. Such a system would need to both senses incoming stimuli and emit a feedback response to eliminate the stimuli. Read More

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http://dx.doi.org/10.1021/jacs.8b13816DOI Listing
April 2019
1 Read

Gecko Adhesion in Space and Time: A Phylogenetic Perspective on the Scansorial Success Story.

Authors:
Aaron M Bauer

Integr Comp Biol 2019 Apr 2. Epub 2019 Apr 2.

Department of Biology, Villanova University, 800 Lancaster Avenue, Villanova, PA, USA.

An evolutionary perspective on gecko adhesion was previously hampered by a lack of an explicit phylogeny for the group and of robust comparative methods to study trait evolution, an underappreciation for the taxonomic and structural diversity of geckos, and a dearth of fossil evidence bearing directly on the origin of the scansorial apparatus. With a multigene dataset as the basis for a comprehensive gekkotan phylogeny, model-based methods have recently been employed to estimate the number of unique derivations of the adhesive system and its role in lineage diversification. Evidence points to a single basal origin of the spinulate oberhautchen layer of the epidermis, which is a necessary precursor for the subsequent elaboration of a functional adhesive mechanism in geckos. Read More

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http://dx.doi.org/10.1093/icb/icz020DOI Listing

A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration.

ACS Cent Sci 2019 Mar 25;5(3):458-467. Epub 2019 Jan 25.

Department of Biomedical Science, College of Life Sciences, CHA University, 335 Pangyo-ro, Bundang-gu, Seongnam, Gyeonggi 13488, Republic of Korea.

Kidney diseases are a worldwide public health issue. Renal tissue regeneration using functional scaffolds with biomaterials has attracted a great deal of attention due to limited donor organ availability. Here, we developed a bioinspired scaffold that can efficiently induce renal tissue regeneration. Read More

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http://pubs.acs.org/doi/10.1021/acscentsci.8b00812
Publisher Site
http://dx.doi.org/10.1021/acscentsci.8b00812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439446PMC
March 2019
6 Reads

Bioinspired Preservation of Natural Killer Cells for Cancer Immunotherapy.

Adv Sci (Weinh) 2019 Mar 27;6(6):1802045. Epub 2019 Jan 27.

Bio-Acoustic-MEMS in Medicine (BAMM) Laboratories Canary Center at Stanford for Cancer Early Detection Department of Radiology Stanford University School of Medicine Palo Alto CA 94304 USA.

The ability to cryopreserve natural killer (NK) cells has a significant potential in modern cancer immunotherapy. Current cryopreservation protocols cause deterioration in NK cell viability and functionality. This work reports the preservation of human cytokine-activated NK cell viability and function following cryopreservation using a cocktail of biocompatible bioinspired cryoprotectants (i. Read More

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http://dx.doi.org/10.1002/advs.201802045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425501PMC
March 2019
1 Read

Motion Simulation of Ionic Liquid Gel Soft Actuators Based on CPG Control.

Comput Intell Neurosci 2019 26;2019:8256723. Epub 2019 Feb 26.

College of Electronics and Information Engineering, Tongji University, No. 4800 Caoan Road, Shanghai 201804, China.

The ionic liquid gel (ILG), a new type of soft actuator material, is a mixture of 1-butyl-3-methylimidazolium tetrafluoroborate (BMIMBF), hydroxyethyl methacrylate (HEMA), diethoxyacetophenone (DEAP), and ZrO polymerized into a gel state under ultraviolet (UV) light irradiation. The soft actuator structure consists of a layer of ionic liquid polymer gel sandwiched between two layers of activated carbon capped with gold foil. The volume of the cationic BMIM in the ionic liquid BMIMBF is much larger than that of the anionic BF. Read More

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https://www.hindawi.com/journals/cin/2019/8256723/
Publisher Site
http://dx.doi.org/10.1155/2019/8256723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413395PMC
February 2019
3 Reads