A Dentin-derived hydrogel bioink for 3D printing of cell laden scaffolds for regenerative dentistry.
- Avathamsa Athirasala,
- Anthony Tahayeri,
- Greeshma Thrivikraman,
- Cristiane Miranda Franca,
- Nelson Monteiro,
- Victor Tran,
- Jack Ferracane,
- Luiz Bertassoni
Biofabrication 2017 Nov 17. Epub 2017 Nov 17.
University of Sydney, Sydney, New South Wales, AUSTRALIA.
Recent studies in tissue engineering have adopted extracellular matrix (ECM) derived scaffolds as natural and cytocompatible microenvironments for tissue regeneration. The dentin matrix, specifically, has been shown to be associated with a host of soluble and insoluble signaling molecules that can promote odontogenesis. Here, we have developed a novel bioink, blending printable alginate (3% w/v) hydrogels with the soluble and insoluble fractions of the dentin matrix. Read More