3 results match your criteria Bioelectronic medicine[Journal]

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Cytokine-specific Neurograms in the Sensory Vagus Nerve.

Bioelectron Med 2016 ;3:7-17

Laboratory of Immune and Neural Networks, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, United States of America.

The axons of the sensory, or afferent, vagus nerve transmit action potentials to the central nervous system in response to changes in the body's metabolic and physiological status. Recent advances in identifying neural circuits that regulate immune responses to infection, inflammation and injury have revealed that vagus nerve signals regulate the release of cytokines and other factors produced by macrophages. Here we record compound action potentials in the cervical vagus nerve of adult mice and reveal the specific activity that occurs following administration of the proinflammatory cytokines tumor necrosis factor (TNF) and interleukin 1β (IL-1β). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039192PMC
January 2016
30 Reads

Vagus Nerve Stimulation for Treatment of Inflammation: Systematic Review of Animal Models and Clinical Studies.

Bioelectron Med 2016 Jan 14;3:1-6. Epub 2016 Sep 14.

Department of Obstetrics and Gynecology and Department of Neurosciences, University of Montreal, Montreal, Quebec, Canada.

Vagus nerve stimulation (VNS) has been used since 1997 for treatment of drug-resistant epilepsy. More recently, an off-label use of VNS has been explored in animal models and clinical trials for treatment of a number of conditions involving the innate immune system. The underlying premise has been the notion of the cholinergic antiinflammatory pathway (CAP), mediated by the vagus nerves. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756070PMC
January 2016
6 Reads

Impact of Bioelectronic Medicine on the Neural Regulation of Pelvic Visceral Function.

Bioelectron Med 2015 Jan;2015:25-36

Department of Pharmacology and Chemical Biology, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America ; Department of Urology, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America.

Neuromodulation elicited by electrical stimulation of peripheral or spinal nerves is a U.S. Food and Drug Administered (FDA)-approved therapy for treating disorders of the pelvic viscera, including urinary urgency, urgency-frequency, nonobstructive urinary retention and fecal incontinence. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610375PMC
January 2015
30 Reads
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