Biochimie 2018 Feb 14. Epub 2018 Feb 14.
CRCINA, Team SOAP, Inserm, CNRS, Université de Nantes, Université D'Angers, France. Electronic address:
Glioblastoma multiforme (GBM) is the most aggressive primary tumour within the brain as well as the most common and lethal cerebral cancer, mainly because of treatment failure. Indeed, tumour recurrence is inevitable and fatal in a short period of time. Glioblastoma stem-like cells (GSCs) are thought to participate in tumour initiation, expansion, resistance to treatments, including to the alkylating chemotherapeutic agent temozolomide, and relapse. Read More