1,329 results match your criteria Biochemistry And Molecular Biology Education[Journal]


Flipped jigsaw activity as a small group peer-assisted teaching learning tool in Biochemistry Department among Indian Medical Graduate: An experimental study.

Biochem Mol Biol Educ 2020 May 19. Epub 2020 May 19.

Department of Biochemistry, Sri Guru Ram Das Institute of Medical Sciences and Research Amritsar, Punjab, India.

Medical council of India has made remarkable modifications in the curriculum of medical students after a long period of more than 20 years with regulations on Graduate Medical Education 1997. Innovative and interactive teaching methods have taken center place in the implementation of the new curriculum nationwide. Small group teaching and problem-assisted learning have brought a paradigm shift in biochemistry teaching, which was earlier teacher cantered and was taught by only didactic lectures due to which biochemistry was considered a boring and dry subject. Read More

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http://dx.doi.org/10.1002/bmb.21355DOI Listing

Publishing your educational research.

Authors:
Paul A Craig

Biochem Mol Biol Educ 2020 May 19. Epub 2020 May 19.

School of Chemistry & Materials Science, Rochester Institute of Technology, Rochester, New York, USA.

Publishing has always been a part of academic tradition and there is increasing pressure on faculty to publish, even those who carry heavy teaching loads. This article, based on a presentation at the IUBMB 2019 Education Conference session on Publishing in Education, contains suggestions on how to conduct educational research with an eye toward publishing your findings. Read More

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http://dx.doi.org/10.1002/bmb.21358DOI Listing
May 2020
0.654 Impact Factor

Something old, something new: Teaching the BMB lab.

Authors:
Paul A Craig

Biochem Mol Biol Educ 2020 May 13. Epub 2020 May 13.

School of Chemistry & Materials Science, Rochester Institute of Technology, Rochester, New York, USA.

Lab courses are a significant component of biochemistry and molecular biology (BMB) education. In teaching the labs, we combine established techniques with novel approaches. Lab formats have also moved from traditional cookbook style labs to guided inquiry to course-based undergraduate research experiences (CUREs), where faculty bring their own research interests into the course setting with a larger number of students in a much more restricted time frame. Read More

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http://dx.doi.org/10.1002/bmb.21359DOI Listing
May 2020
0.654 Impact Factor

Evolution of an 8-week upper-division metagenomics course: Diagramming a learning path from observational to quantitative microbiome analysis.

Biochem Mol Biol Educ 2020 Apr 15. Epub 2020 Apr 15.

College of Natural and Mathematical Sciences, University of Maryland, Baltimore County, Baltimore, Maryland, USA.

Metagenomics is a tool that enables researchers to study genetic material recovered directly from microbial communities or microbiomes. Fueled by advances in sequencing technologies, bioinformatics tools, and sample processing, metagenomics studies promise to expand our understanding of human health and the use of microorganisms for agriculture and industry. Therefore, teaching students about metagenomics is crucial to prepare them for modern careers in the life sciences. Read More

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http://dx.doi.org/10.1002/bmb.21349DOI Listing

Using anticipated learning outcomes for backward design of a molecular cell biology Course-based Undergraduate Research Experience.

Biochem Mol Biol Educ 2020 Apr 13. Epub 2020 Apr 13.

Department of Biological Sciences, Faculty of Arts and Science, MacEwan University, Edmonton, Alberta, Canada.

Anticipated learning outcomes (LOs) were defined and used for the backward design of a Course-based Undergraduate Research Experience (CURE). These LOs reflect the inquiry-based nature of CUREs and capture key knowledge and skills inherent to scientific practice and essential in research. The LOs were used to plan a formative and summative assessment strategy to support and evaluate student achievement. Read More

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http://dx.doi.org/10.1002/bmb.21350DOI Listing

A low-cost, in silico nutritional genomics course-based undergraduate research experience applicable to multiple disciplines.

Authors:
Deborah J Good

Biochem Mol Biol Educ 2020 Apr 11. Epub 2020 Apr 11.

Department of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, Virginia, USA.

This article describes the development and assessment of a Nutritional Genomics course, designed to be held in a regular classroom during normal class periods, with few extra costs to the students or the department. The course was run as an upper-level undergraduate and lower-level graduate student course. Student taking the course spent 11 weeks learning and then 4 weeks using various in silico methods to independently characterize genes of interest in the field. Read More

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http://dx.doi.org/10.1002/bmb.21352DOI Listing

Commentary: Challenges for PhD students during COVID-19 pandemic: Turning crisis into an opportunity.

Biochem Mol Biol Educ 2020 Apr 9. Epub 2020 Apr 9.

Biochemistry Department, School of Medicine, Koc University, Istanbul, Turkey.

COVID-19 results in the suspension of life all over the world. Universities suspended their academic activities except for online courses for undergrad and grad students. However, PhD students in both biochemistry and molecular biology fields must hold their experiments at the laboratories. Read More

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http://dx.doi.org/10.1002/bmb.21351DOI Listing

Forster resonance energy transfer for studying nucleic acids denaturation: A chemical and biological sciences laboratory experiment.

Biochem Mol Biol Educ 2020 Apr 8. Epub 2020 Apr 8.

CICS-UBI - Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal.

The Förster resonance energy transfer (FRET) melting assay intends to evaluate the unfolding, denaturation process of DNA secondary structures, and its stabilization using compounds known as DNA binders, some of which are highly specific for G-quadruplex DNAs versus duplex DNAs. First, students determined the melting temperature (T ) of DNA sequences double labeled with 5'-FAM (fluorescein) and 3'-TAMRA (tetramethylrhodamine) in the absence of DNA binders. Second, they determined the melting temperature of the DNAs in the presence of DNA binders by monitoring fluorescence. Read More

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http://dx.doi.org/10.1002/bmb.21353DOI Listing

Teaching in the time of COVID-19.

Authors:
Phillip A Ortiz

Biochem Mol Biol Educ 2020 Apr 2. Epub 2020 Apr 2.

Editor-in-Chief, Biochemistry and Molecular Biology Education, and State University of New York, Albany, New York.

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http://dx.doi.org/10.1002/bmb.21348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228309PMC

An idea to explore: A collaboration and cross training in an extended classroom-based undergraduate research experience between primarily undergraduate and research-intensive institutions.

Biochem Mol Biol Educ 2020 Mar 28. Epub 2020 Mar 28.

Clowes Department of Chemistry and Biochemistry, Butler University, Indianapolis, Indiana, USA.

Providing students with training in advanced laboratory skills is an essential part of scientific education. At the same time, engaging students in research is becoming equally important. Classroom-based undergraduate research experiences (CUREs) have emerged to fill this need, and can take many forms. Read More

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http://dx.doi.org/10.1002/bmb.21340DOI Listing

IUBMB/PSBMB 2019 Conference/Plenary: Mentoring in biochemical education and research: Traditional, structured, and institutional.

Biochem Mol Biol Educ 2020 Mar 24. Epub 2020 Mar 24.

Institute of Plant Breeding, College of Agriculture and Food Science, University of the Philippines Los Baños, Los Baños, Laguna, Philippines.

Mentoring to many is the informal highly unstructured teaching, advising, and nurturing which we receive from various individuals during our school years and professional lives and then give back to our students and more junior colleagues. However, with the advances in science and technology, the increasing competitiveness in the workplace, fast pace of life, and globalization, the importance of proper mentoring in the training of science professionals has gained the attention of and has been discussed and studied by higher institutions of learning and national academies of science. During the past two decades, efforts toward making mentoring more structured by national academies of sciences and academic and professional institutions have produced guidelines, mentoring programs for mentors and mentees, faculty, students, scholarly research publications on mentoring, and related aspects. Read More

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http://dx.doi.org/10.1002/bmb.21346DOI Listing

IUBMB/PSBMB 2019 Conference/Plenary: National Program Accreditation. Does it help drive change and support faculty and student or does it limit our creativity?

Authors:
Joseph J Provost

Biochem Mol Biol Educ 2020 Mar 24. Epub 2020 Mar 24.

Department of Chemistry and Biochemistry, University of San Diego, San Diego, California, USA.

Accreditation of academic programs and recognition of student degrees provide academic institutions a measure of a set of community agreed upon standards. These can aid pedagogical change, support faculty to successfully engage students in their discipline and to provide a mechanism to maintain standards. Several professional scientific societies from engineering, chemistry, and biochemistry and molecular biology have developed standards by which departments can be recognized for accreditation. Read More

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http://dx.doi.org/10.1002/bmb.21343DOI Listing

Scientists in education: A biomedical research institute's perspective.

Biochem Mol Biol Educ 2020 Mar 24. Epub 2020 Mar 24.

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.

The Institute for Research in Biomedicine (IRB Barcelona) is a world-class research center devoted to understanding fundamental questions about human health and disease. In addition to conducting multidisciplinary research of excellence, IRB Barcelona is committed to maintaining an open dialogue with the public about its work, fostering scientific vocations and promoting scientific culture in society. In this regard, the institute has several public engagement and science education initiatives to reach these goals. Read More

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http://dx.doi.org/10.1002/bmb.21344DOI Listing

Developing and applying computational resources for biochemistry education.

Authors:
Paul A Craig

Biochem Mol Biol Educ 2020 Mar 23. Epub 2020 Mar 23.

School of Chemistry and Materials Science, Rochester Institute of Technology, Rochester, New York, USA.

Biochemistry is about structure and function, but it is also about data and this is where computers come in. From my time as a graduate student and post doc, whenever I encountered data I thought, "I can work this up by hand, but I think a computer could do a better job." Since that time, I have been working at the interface of biochemistry and computers, by attracting talented students and collaborating with colleagues with complementary skills. Read More

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http://dx.doi.org/10.1002/bmb.21347DOI Listing
March 2020
0.654 Impact Factor

IUBMB/PSBMB 2019 Conference/Plenary: Mentoring in postgraduate training and the role of Organization for PhD Education in Health Sciences in European System.

Authors:
Hakan S Orer

Biochem Mol Biol Educ 2020 Mar 23. Epub 2020 Mar 23.

Koç University School of Medicine, Department of Medical Pharmacology, Istanbul, Turkey.

A vibrant and sustainable research environment is essential to establish a thriving PhD program. Organization for PhD Education in Health Sciences in European System, a European platform to promote best practices in PhD education in health sciences, published a guideline entitled "Best Practices for PhD Training." The guideline includes comprehensive recommendations and suggestions on different components of the PhD program, of which supervision is an essential one. Read More

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http://dx.doi.org/10.1002/bmb.21345DOI Listing

An idea to explore: Use of augmented reality for teaching three-dimensional biomolecular structures.

Biochem Mol Biol Educ 2020 Mar 23. Epub 2020 Mar 23.

Department of Chemistry and Biochemistry, Suffolk University, Boston, Massachusetts, USA.

Biology and biochemistry students must learn to visualize and comprehend the complex three-dimensional (3D) structures of macromolecules such as proteins or DNA. However, most tools available for teaching biomolecular structures typically operate in two dimensions. Here, we present protocols and pedagogical approaches for using immersive augmented reality (AR) visors, specifically the Microsoft HoloLens, to reinforce learning with large scale 3D holographic structures. Read More

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http://dx.doi.org/10.1002/bmb.21341DOI Listing

Metallothionein determination can be applied to learn about aquatic metal pollution and oxidative stress detoxification mechanisms through Problem-based Learning.

Biochem Mol Biol Educ 2020 Mar 13. Epub 2020 Mar 13.

Instituto de Educação da Universidade de Lisboa, Alameda da Universidade, 1649-013, Lisboa, Portugal.

A simple, repeatable and inexpensive laboratory practice applied to teach and discuss aquatic metal pollution and oxidative stress detoxification mechanisms through biomarker analyses, as well as important ecotoxicology concepts, is presented herein. It has been implemented in a university in Brazil to both undergraduate and Master's and PhD students, indicating usefulness to all these levels. Students learned to detect metallothionein and reduced glutathione concentrations in biological samples and investigate several variables of interest in biomonitoring assessments. Read More

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http://dx.doi.org/10.1002/bmb.21342DOI Listing

Separation of mononuclear cells and identification of B lymphocytes: A comprehensive experiment for medical students.

Biochem Mol Biol Educ 2020 Mar 5. Epub 2020 Mar 5.

Teaching Laboratory Center of Medicine and Life Science, Tongji University School of Medicine, Shanghai, China.

In teaching of experiments for medical students, by using the isolation of mononuclear cells and identification of B lymphocytes, an experiment was developed that integrated biochemistry, cytology, and immunology techniques, from which the students performed a series of operations including spleen separation, isolating mononuclear cells, and identifying B lymphocytes. From the immunocytochemistry detection, we included advanced equipment-a flow cytometer-in the experiment, which detected the B lymphocytes more accurately. Moreover, we applied modern information technology to the teaching of experiments by using an internet study platform, micro-lectures, and adopting "formative teaching and evaluation. Read More

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http://dx.doi.org/10.1002/bmb.21338DOI Listing
March 2020
0.654 Impact Factor

A new twist on the graduate student journal club: Using a topic-centered approach to promote student engagement.

Biochem Mol Biol Educ 2020 Feb 20. Epub 2020 Feb 20.

Master of Science in Science Education Program, Montana State University, Bozeman, Montana.

Journal clubs are widely used as an educational tool in graduate life science programs. In journal clubs, students are assigned to read specific journal articles to achieve a broad knowledge in their field of study and to gain competence in reading and assessing scientific publications. However, students often show low motivation to read assigned articles, and under-prepared students contribute little to in-class discussions. Read More

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http://dx.doi.org/10.1002/bmb.21337DOI Listing
February 2020

An accessible, open-source mobile application for macromolecular visualization using augmented reality.

Biochem Mol Biol Educ 2020 Feb 20. Epub 2020 Feb 20.

Computational Biology Programme, National University of Singapore, Singapore, Singapore.

Understanding macromolecular structures is essential for biology education. Augmented reality (AR) applications have shown promise in science, technology, engineering, and mathematics (STEM) education, but are not widely used for protein visualization. While there are some tools for AR protein visualization, none of them are accessible to the layperson who possesses neither specialized AR hardware nor the technical skill to comfortably navigate three-dimensional (3D) rendering and file conversions. Read More

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http://dx.doi.org/10.1002/bmb.21335DOI Listing
February 2020

From pK to the pH of weak base solutions.

Authors:
James P McEvoy

Biochem Mol Biol Educ 2020 Feb 10. Epub 2020 Feb 10.

Department of Biological Sciences, Royal Holloway, University of London, Egham, UK.

Undergraduate biochemistry students frequently find the quantitative treatment of weak acids and bases troublesome. Given the pK of a weak acid HA, for instance, many students struggle to calculate the pH of a solution of the conjugate base A at concentration C, pH(A , C). The traditional method involves calculating the base dissociation constant K and the artificial quantity pOH before reaching pH, but these steps increase the risk of mistakes and provide little insight into acid-base equilibria. Read More

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http://dx.doi.org/10.1002/bmb.21336DOI Listing
February 2020

Lab experience with seafood control at the undergraduate level: Cephalopods as a case study.

Biochem Mol Biol Educ 2020 Jan 16. Epub 2020 Jan 16.

Department of Functional Biology, Genetics, Universidad de Oviedo, Oviedo, Asturias, Spain.

The correct labeling of seafood is important to protect nature and the rights of consumers. Given the certainty that the resources of the sea are not inexhaustible, only strict regulations and the implementation of sustainable fishing systems and reliable and traceable marketing systems can help ensure the long-term sustainability of fishery resources. Detecting mislabeling and seafood fraud is a useful resource for improving students' motivation and developing active learning methodologies in higher education. Read More

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http://dx.doi.org/10.1002/bmb.21332DOI Listing
January 2020

Erratum.

Authors:

Biochem Mol Biol Educ 2020 Jan 15;48(1):84. Epub 2019 Nov 15.

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http://dx.doi.org/10.1002/bmb.21315DOI Listing
January 2020

Drawing in 3D: Using 3D printer pens to draw chemical models.

Biochem Mol Biol Educ 2020 Jan 3. Epub 2020 Jan 3.

Indiana University - Purdue University Columbus, Columbus, Indiana.

Development of three-dimensional (3D) printing technology has started a new chapter for in-classroom modeling of chemical molecules. The technology provides the opportunity to design and produce various types of personalized models. However, using classical 3D printers is time consuming, and it is hard to involve students in the modeling process during traditional class times. Read More

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http://dx.doi.org/10.1002/bmb.21334DOI Listing
January 2020

An inquiry-based approach in large undergraduate labs: Learning, by doing it the "wrong" way.

Biochem Mol Biol Educ 2020 Jan 3. Epub 2020 Jan 3.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sahibzada Ajit Singh Nagar, Punjab, India.

Undergraduate laboratory courses, owing to their larger sizes and shorter time slots, are often conducted in highly structured modes. However, this approach is known to interfere with students' engagement in the experiments. To enhance students' engagement, we propose an alternative mode of running laboratory courses by creating some "disorder" in a previously adopted structure. Read More

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http://dx.doi.org/10.1002/bmb.21331DOI Listing
January 2020

Choosing the adequate thermodynamic reference state: The evolution of pyrophosphate bioenergetics as an example.

Authors:
Eduardo Méndez

Biochem Mol Biol Educ 2020 Jan 3. Epub 2020 Jan 3.

Laboratorio de Biomateriales, Instituto de Química Biológica, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.

The use of the thermodynamic formalism in the investigation of biochemical reactions constitutes one of the key analysis in bioenergetics, and the first step in such analysis is the selection of the adequate reference state. For biochemistry majors, thermodynamic analysis based on the chemical reference state is used in Physical Chemistry courses, while the biological and biochemical reference states are used in Biochemistry courses. As these definitions are introduced in different courses, it is difficult that students can understand the need to select a reference state as a first step in the energy analysis of a system. Read More

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http://dx.doi.org/10.1002/bmb.21333DOI Listing
January 2020

Adopting a flipped classroom approach for teaching molar calculations to biochemistry and genetics students.

Biochem Mol Biol Educ 2019 Dec 30. Epub 2019 Dec 30.

Department of Biochemistry and Genetics, Swansea University Medical School, Swansea, Wales.

The flipped classroom is a relatively new active learning pedagogical intervention, gaining popularity as a blended learning methodology. The flipped classroom comprises two distinct parts, directed learning carried out at the student's own pace away from the classroom and an interactive, class-based activity encouraging problem-solving and experiential learning. This research presents a 1-year study to measure student performance and perception toward a flipped classroom approach to teaching core biochemical calculations to first-year undergraduate biochemistry and genetics students. Read More

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http://dx.doi.org/10.1002/bmb.21328DOI Listing
December 2019

Editorial: Publishing "negative" results.

Authors:
Phillip A Ortiz

Biochem Mol Biol Educ 2020 01 23;48(1). Epub 2019 Dec 23.

Editor-in-Chief, Biochemistry and Molecular Biology Education, and State University of New York, Albany, New York.

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http://dx.doi.org/10.1002/bmb.21329DOI Listing
January 2020

Application of Ausubel cognitive assimilation theory in teaching/learning medical biochemistry and molecular biology.

Biochem Mol Biol Educ 2019 Dec 20. Epub 2019 Dec 20.

School of Biomedical Sciences and Technology, Chengdu Medical College, Chengdu, Sichuan, China.

"Didn't understand or not fully understand" is the most common situation that students experience when they learn medical biochemistry and molecular biology (MBMB). Therefore, the primary task of teaching MBMB is to help students overcome the difficulties in "conceptual understanding." The core of the solution to these problems lies in the acquisition and application of cognitive skills. Read More

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http://dx.doi.org/10.1002/bmb.21327DOI Listing
December 2019

Harnessing single-stranded DNA binding protein to explore protein-protein and protein-DNA interactions.

Biochem Mol Biol Educ 2020 03 18;48(2):181-190. Epub 2019 Dec 18.

Biotechnology Program, North Carolina State University, Raleigh, North Carolina.

Proteins must interact with a variety of other cellular components to properly perform their functions. We have developed a series of five experiments based on the robust bacterial single-stranded DNA binding protein (SSB) to characterize both known and unknown protein-protein and protein-DNA interactions. Students work in groups to generate and process data from electrophoretic mobility shift assays (EMSA), yeast two-hybrid, far Western, chromatin immunoprecipitation (ChIP), and fluorescence microscopy experiments, including choosing a novel condition for each. Read More

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http://dx.doi.org/10.1002/bmb.21324DOI Listing

Insights from the new horizons in biochemistry and molecular biology education conference. September 6-8, 2017, Rehovot, Israel.

Biochem Mol Biol Educ 2020 03 18;48(2):93-98. Epub 2019 Dec 18.

Department of Science Teaching, The Weizmann Institute of Science, Rehovot, Israel.

The New Horizons in Biochemistry and Molecular Biology Education Conference was organized by the International Union of Biochemistry and Molecular Biology (IUBMB) in collaboration with the Federation of European Biochemical Societies (FEBS), and the Weizmann Institute of Science (Israel) and held in Rehovot, Israel, on September 6-8, 2017. The program covered the entire lifespan of students/scientists from the school level to undergraduate, graduate, and post-doctoral levels and brought together 130 international participants. This article provides an overview of the major issues and topics discussed at the conference and suggestions for the way forward. Read More

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http://dx.doi.org/10.1002/bmb.21323DOI Listing

Course-based prefaculty training program introduces instructional methods, increases instructor self-efficacy, and promotes professional development.

Biochem Mol Biol Educ 2020 03 17;48(2):156-167. Epub 2019 Dec 17.

Yale Poorvu Center for Teaching and Learning, Yale University, New Haven, Connecticut.

Graduate student and postdoctoral teaching assistants receive highly variable preparation for instructional methods because providing such training is often expensive. Therefore, we conducted an intensive, pedagogical boot camp followed by classroom observations, structured professional development discussions about leveraging the experience on the job market, individual exit interviews, and a letter of recommendation. Our data show the participants implemented new pedagogical techniques in their classrooms, showed increased self-efficacy, and reported appreciation for the training experience. Read More

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http://dx.doi.org/10.1002/bmb.21326DOI Listing

Why a grassroots Summer Institutes model failed: Exploring obstacles to evidence-based teaching awareness in low-awareness, low-support contexts.

Authors:
Justin Fendos

Biochem Mol Biol Educ 2020 03 16;48(2):143-155. Epub 2019 Dec 16.

Global Biotechnology, Dongseo University, Busan, South Korea.

As a global phenomenon, the spread of evidence-based teaching (EBT) in STEM education has been very uneven. Outside of the United States, parts of Europe, and Oceania, EBT awareness is generally regarded as being extremely low. In the United States, programs like the Summer Institutes (SI) have been used to help disseminate awareness and train faculty, precipitating efforts to understand EBT implementation barriers. Read More

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http://dx.doi.org/10.1002/bmb.21325DOI Listing
March 2020
5 Reads

A laboratory practice that uses the polymerase chain reaction-sequence specific priming technique to rapidly screen for HLA-DR2 allotype from germline DNA in immunology course for undergraduate medical students.

Biochem Mol Biol Educ 2020 03 3;48(2):175-180. Epub 2019 Dec 3.

Laboratory of Cellular and Molecular Biology, College of Basic Medical Sciences, Central South University, Changsha, Hunan, China.

In this article, we describe an in-house polymerase chain reaction-sequence specific priming (PCR-SSP) assay designed for undergraduate medical students as part of the experimental pathogen biology and immunology (EPBI) course. It screens human leukocyte antigen (HLA)-DR2 allotype from genomic DNA samples using a rapid and single-tube PCR technique, yielding definitive typing result without conventional post-amplification step like probing or Sanger sequencing. This laboratory exercise offers the undergraduate medical students an opportunity to learn about current molecular biology techniques in HLA genotyping with limited effort and cost, in addition to a better understanding of concepts presented in the classroom lectures. Read More

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http://dx.doi.org/10.1002/bmb.21322DOI Listing

Reflections on integrating bioinformatics into the undergraduate curriculum: The Lancaster experience.

Authors:
Derek Gatherer

Biochem Mol Biol Educ 2020 03 2;48(2):118-127. Epub 2019 Dec 2.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.

Bioinformatics is an essential discipline for biologists. It also has a reputation of being difficult for those without a strong quantitative and computer science background. At Lancaster University, we have developed modules for the integration of bioinformatics skills training into our undergraduate biology degree portfolio. Read More

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http://dx.doi.org/10.1002/bmb.21320DOI Listing

Implementation of research on potential drug target cloning and characterization in a biochemistry laboratory.

Biochem Mol Biol Educ 2020 03 29;48(2):108-117. Epub 2019 Nov 29.

Division of Natural Sciences, Mount Marty College, Yankton, South Dakota.

An approach for incorporating preliminary drug discovery research into a biochemistry laboratory is described. During a total of 42 hr (one 3-hr laboratory section a week for 14 weeks), students were exposed to bioinformatics; molecular cloning; protein expression, purification, and characterization; and enzymatic kinetic assays. This research-oriented laboratory not only includes the standard elements of common undergraduate biochemistry laboratory manuals but also emphasizes the logical connections among biochemistry laboratory techniques. Read More

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http://dx.doi.org/10.1002/bmb.21319DOI Listing

Evaluation of a staged case-based discussion curriculum in standardized residency training.

Biochem Mol Biol Educ 2020 03 29;48(2):128-133. Epub 2019 Nov 29.

Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.

The standardized residency training in China is continuous medical education for postgraduates, which is designed to master basic knowledge, theory, and clinical skills. Case-based discussion (CBD) is one of the main formative curricula used in standardized residency training. The aim of this study was to assess the impact of a novel CBD curriculum on residents' participation, satisfaction, and confidence in clinical skills. Read More

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http://dx.doi.org/10.1002/bmb.21321DOI Listing

Integrating scientific literacy skills into a biochemistry course for nonscience majors.

Authors:
Ann T S Taylor

Biochem Mol Biol Educ 2020 01 14;48(1):54-60. Epub 2019 Nov 14.

Chemistry Department, Wabash College, Crawfordsville, Indiana.

One of the goals for requiring all college students to take science courses is to develop critical thinking about scientific issues they will encounter as citizens, consumers, and patients. This article integrates skill development activities targeting civic scientific literacy skills in a nonscience majors (liberal arts) biochemistry course, but similar principles could be integrated into nursing and major levels biochemistry courses. Strategies include teaching information acquisition, source analysis argument analysis, and civic engagement. Read More

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http://dx.doi.org/10.1002/bmb.21313DOI Listing
January 2020

An exploratory study comparing students' science identity perceptions derived from a hands-on research and nonresearch-based summer learning experience.

Biochem Mol Biol Educ 2020 03 14;48(2):134-142. Epub 2019 Nov 14.

Biology Department, University of Puerto Rico, Río Piedras Campus, San Juan, Puerto Rico.

Although multiple efforts have been initiated to increase students' science proficiency scores, most of the schools in the United States do not reach the expected student academic performance. This study addresses the impact of a one-week summer scientific learning experience on students that worked with experimental procedures and students that did not. We describe and evaluate these two different interventions to explore what components influence high school students' perception of their scientific competence, performance, and recognition, using science identity as an analytical lens. Read More

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http://dx.doi.org/10.1002/bmb.21314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079089PMC

A full semester flow cytometry course improves graduate and undergraduate student confidence.

Biochem Mol Biol Educ 2020 03 12;48(2):99-107. Epub 2019 Nov 12.

Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah.

Flow cytometry is a versatile and high throughput technique for rapid and efficient biological testing. It requires a high level of conceptual, technical, and analytical skills to properly design experiments, effectively operate flow cytometry machines, and analyze the data. A lack of training and development of any of these three skills can result in underutilization and improper use of flow cytometric machines that can impede research progress. Read More

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http://dx.doi.org/10.1002/bmb.21318DOI Listing

Design, implementation, and outcomes of an elective course on preliminary structural biology for undergraduate students majoring in biotechnology.

Biochem Mol Biol Educ 2020 03 30;48(2):168-174. Epub 2019 Oct 30.

National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Army Medical University, Chongqing, China.

Biotechnological pharmaceuticals is a key course offered to third-year undergraduates majoring in biotechnology in our university. However, students often experience difficulties in understanding the principles of related technologies. In this study, we developed and implemented an elective course on preliminary structural biology for biotechnology undergraduates, aiming at reinforcing the principles of these technologies by experimental practice. Read More

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http://dx.doi.org/10.1002/bmb.21312DOI Listing
March 2020
1 Read

LabSafety, the Pharmaceutical Laboratory Android Application, for Improving the Knowledge of Pharmacy Students.

Biochem Mol Biol Educ 2020 01 28;48(1):44-53. Epub 2019 Oct 28.

Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.

Currently, traditional paper methods may not effectively be used in education due to lack of access, outdated content, and poor graphics. Education through mobile-based applications is one of the alternative solutions. The objective of this study was to develop and evaluate LabSafety educational application and its effect on promoting the knowledge of pharmacy students. Read More

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http://dx.doi.org/10.1002/bmb.21311DOI Listing
January 2020
0.654 Impact Factor

Website of Note: Study Design 101.

Biochem Mol Biol Educ 2020 01 9;48(1):80-81. Epub 2019 Oct 9.

Himmelfarb Health Sciences Library, The George Washington University, Washington, District of Columbia.

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http://dx.doi.org/10.1002/bmb.21306DOI Listing
January 2020

The horseradish smile: Demonstrating characteristic reactions of peroxidase in a visually appealing way.

Authors:
Guido Panzarasa

Biochem Mol Biol Educ 2020 01 9;48(1):38-43. Epub 2019 Oct 9.

Department of Polymer Engineering and Science, Montanuniversität, Leoben, 8700, Austria.

Easy and visually appealing demonstrations are precious tools for introducing students to the study of enzymes. However, they most often involve purified enzymes and dedicated techniques. Here, we propose a set of demonstrations, which require only fresh horseradish root and consumer chemicals, to help support biochemistry and enzymology courses from high school to the undergraduate level. Read More

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http://dx.doi.org/10.1002/bmb.21310DOI Listing
January 2020

Exploring the inquiry-based learning structure to promote scientific culture in the classrooms of higher education sciences.

Biochem Mol Biol Educ 2019 11 6;47(6):672-680. Epub 2019 Oct 6.

Grupo de Estudos e Pesquisa em Ensino & Ciências (GEPEC), Escola de Ciências Biológicas e da Saúde, Centro Universitário das Faculdades Metropolitanas Unidas, FMU, São Paulo, Brazil.

This article examines student engagement in an inquiry-based learning activity, planned to provide students with elements in the social, epistemic, and conceptual dimensions related to the scientific practice in immunology. The activity was applied to 39 groups of students enrolled in immunology or biochemistry courses in a public university in Brazil. Students performed data-collection through the execution of an in vitro assay. Read More

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http://dx.doi.org/10.1002/bmb.21301DOI Listing
November 2019

Implementation and Evaluation of a Three-Dimensional Virtual Reality Biology Lab versus Conventional Didactic Practices in Lab Experimenting with the Photonic Microscope.

Biochem Mol Biol Educ 2020 01 30;48(1):21-27. Epub 2019 Sep 30.

School of Science and Technology, Hellenic Open University, Patras, 26335, Greece.

This study presents the integration of three different teaching scenarios, during biology laboratory lessons, with the overall aim of exploring the potential predominant effectiveness of teaching and improvement of students' learning, by the use of the three-dimensional virtual reality educational tool Onlabs, versus more traditional didactic practices. A sample of 83, fourth year, undergraduate students of the Primary Education Department of Patras' University in Greece, were equally separated into three cognitively balanced groups to be educated on the light microscopy experiment by three different educational scenarios. Students' conceptual understanding in the domain of microscopy, was evaluated during all learning procedure with Pre and Post tests, whereas their skill to handle properly a real light microscope in the wet biology lab was summatively assessed via a specially designed work sheet. Read More

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http://dx.doi.org/10.1002/bmb.21307DOI Listing
January 2020

The Multilevel Inquiry Approach to Achieving Meaningful Learning in Biochemistry Course.

Biochem Mol Biol Educ 2020 01 30;48(1):28-37. Epub 2019 Sep 30.

Study Program of Chemistry Education, Faculty of Teacher Training and Education, Universitas Mataram, Mataram, Indonesia.

Biochemistry learning in higher education not only aims to allow students to remember the concepts learned, but also to achieve meaningful learning. This study examines the implementation of the multilevel inquiry approach in order to achieve meaningful biochemistry learning. Such as approach begins with a structured inquiry, leading to a guided inquiry, and ending with an open inquiry on topics that are connected to each other. Read More

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http://dx.doi.org/10.1002/bmb.21309DOI Listing
January 2020

Simulated sandwich enzyme-linked immunosorbent assay for a cost-effective investigation of natural and engineered cellular signaling pathways.

Authors:
Paul R Jaschke

Biochem Mol Biol Educ 2020 01 18;48(1):67-73. Epub 2019 Sep 18.

Department of Molecular Sciences, Macquarie University, Sydney, 2109, New South Wales, Australia.

The ability to separate, identify, and quantify proteins from complex mixtures are key foundational methods across biochemistry teaching and research. In particular, enzyme-linked immunosorbent assay (ELISA) is an important technique that is used to measure antigen concentrations in both industry and academia. There are four categories of ELISA, direct, indirect, competitive, and sandwich, each with their own applications. Read More

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http://dx.doi.org/10.1002/bmb.21304DOI Listing
January 2020
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Teaching structural diversity of hexoses to graduate and postgraduate students: Methods to correlate stereochemistry.

Biochem Mol Biol Educ 2020 01 18;48(1):8-20. Epub 2019 Sep 18.

International Research Centre for Climate Change Studies, Sathyabama Institute of Science and Technology, Old Mahabalipuram Road, Chennai, Tamil Nadu, 600119, India.

Carbohydrates, or in strictly chemical terms, polyhydroxy-aldehydes or ketones represent enormous structural diversity in terms of the arrangement of atoms in space, resulting in hundreds of stereoisomers. Although the chemical properties of most stereoisomers may not be very different, their metabolic fate and utilization in biological systems is significantly different and known to influence the overall carbohydrate metabolism. This dictates the importance of understanding the structures of various stereochemical structures for a biochemist. Read More

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http://dx.doi.org/10.1002/bmb.21305DOI Listing
January 2020
0.654 Impact Factor