1,670 results match your criteria BioMedical Engineering OnLine [Journal]


Automated computer-assisted detection system for cerebral aneurysms in time-of-flight magnetic resonance angiography using fully convolutional network.

Biomed Eng Online 2020 May 29;19(1):38. Epub 2020 May 29.

Department of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China.

Background: As the rupture of cerebral aneurysm may lead to fatal results, early detection of unruptured aneurysms may save lives. At present, the contrast-unenhanced time-of-flight magnetic resonance angiography is one of the most commonly used methods for screening aneurysms. The computer-assisted detection system for cerebral aneurysms can help clinicians improve the accuracy of aneurysm diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00770-7DOI Listing

Chronic vagus nerve stimulation for drug-resistant epilepsy may influence fasting blood glucose concentration.

Biomed Eng Online 2020 May 29;19(1):40. Epub 2020 May 29.

Research Center for Biomedical Engineering, Medical Innovation & Research Division, Chinese PLA General Hospital, Beijing, 100853, China.

Background: Cervical vagus nerve stimulation (VNS) has been widely accepted as adjunctive therapy for drug-resistant epilepsy and major depression. Its effects on glycemic control in humans were however poorly understood. The aim of our study was to investigate the potential effects of VNS on fasting blood glucose (FBG) in patients with drug-resistant epilepsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00784-1DOI Listing

Radiotherapy dose distribution prediction for breast cancer using deformable image registration.

Biomed Eng Online 2020 May 29;19(1):39. Epub 2020 May 29.

Key Laboratory of Radiation Physics and Technology, Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, China.

Background: Radiotherapy treatment planning dose prediction can be used to ensure plan quality and guide automatic plan. One of the dose prediction methods is incorporating historical treatment planning data into algorithms to estimate the dose-volume histogram (DVH) of organ for new patients. Although DVH is used extensively in treatment plan quality and radiotherapy prognosis evaluation, three-dimensional dose distribution can describe the radiation effects more explicitly. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00783-2DOI Listing

Clutter suppression in ultrasound: performance evaluation and review of low-rank and sparse matrix decomposition methods.

Biomed Eng Online 2020 May 28;19(1):37. Epub 2020 May 28.

Department of Electrical and Computer Engineering, Concordia, Rue Sainte-Catherine O, Montreal, Canada.

Vessel diseases are often accompanied by abnormalities related to vascular shape and size. Therefore, a clear visualization of vasculature is of high clinical significance. Ultrasound color flow imaging (CFI) is one of the prominent techniques for flow visualization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00778-zDOI Listing

Acoustic analysis and detection of pharyngeal fricative in cleft palate speech using correlation of signals in independent frequency bands and octave spectrum prominent peak.

Biomed Eng Online 2020 May 27;19(1):36. Epub 2020 May 27.

College of Electrical Engineering, Sichuan University, 610065, Chengdu, China.

Background: Pharyngeal fricative is one typical compensatory articulation error of cleft palate speech. It passively influences daily communication for people who suffer from it. The automatic detection of pharyngeal fricatives in cleft palate speech can provide information for clinical doctors and speech-language pathologists to aid in diagnosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00782-3DOI Listing

Functional electrical stimulation therapy for restoration of motor function after spinal cord injury and stroke: a review.

Biomed Eng Online 2020 May 24;19(1):34. Epub 2020 May 24.

Kite Research Institute, Toronto Rehabilitation Institute-University Health Network, 550 University Avenue, Toronto, ON, M5G 2A2, Canada.

Functional electrical stimulation is a technique to produce functional movements after paralysis. Electrical discharges are applied to a person's muscles making them contract in a sequence that allows performing tasks such as grasping a key, holding a toothbrush, standing, and walking. The technology was developed in the sixties, during which initial clinical use started, emphasizing its potential as an assistive device. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00773-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245767PMC

Validation of conductivity tensor imaging using giant vesicle suspensions with different ion mobilities.

Biomed Eng Online 2020 May 24;19(1):35. Epub 2020 May 24.

Department of Biomedical Engineering, Kyung Hee University, 26, Kyungheedae-ro, Seoul, 02447, South Korea.

Background: Electrical conductivity of a biological tissue at low frequencies can be approximately expressed as a tensor. Noting that cross-sectional imaging of a low-frequency conductivity tensor distribution inside the human body has wide clinical applications of many bioelectromagnetic phenomena, a new conductivity tensor imaging (CTI) technique has been lately developed using an MRI scanner. Since the technique is based on a few assumptions between mobility and diffusivity of ions and water molecules, experimental validations are needed before applying it to clinical studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00780-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247266PMC

Measuring lung mechanics of expiratory tidal breathing with non-invasive breath occlusion.

Biomed Eng Online 2020 May 14;19(1):32. Epub 2020 May 14.

Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand.

Background And Objective: Lung mechanics measurements provide clinically useful information about disease progression and lung health. Currently, there are no commonly practiced methods to non-invasively measure both resistive and elastic lung mechanics during tidal breathing, preventing the important information provided by lung mechanics from being utilised. This study presents a novel method to easily assess lung mechanics of spontaneously breathing subjects using a dynamic elastance, single-compartment lung model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00777-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224083PMC

Motor improvement estimation and task adaptation for personalized robot-aided therapy: a feasibility study.

Biomed Eng Online 2020 May 14;19(1):33. Epub 2020 May 14.

Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne, Switzerland.

Background: In the past years, robotic systems have become increasingly popular in upper limb rehabilitation. Nevertheless, clinical studies have so far not been able to confirm superior efficacy of robotic therapy over conventional methods. The personalization of robot-aided therapy according to the patients' individual motor deficits has been suggested as a pivotal step to improve the clinical outcome of such approaches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00779-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227346PMC

Using pulse oximetry waveforms to detect coarctation of the aorta.

Biomed Eng Online 2020 May 14;19(1):31. Epub 2020 May 14.

Division of Cardiology, Pediatric Cardiology, Children's Healthcare of Atlanta, 1405 Clifton Rd, Atlanta, GA, 30322, USA.

Background: Coarctation of the aorta is a common form of critical congenital heart disease that remains challenging to diagnose prior to clinical deterioration. Despite current screening methods, infants with coarctation may present with life-threatening cardiogenic shock requiring urgent hospitalization and intervention. We sought to improve critical congenital heart disease screening by using a novel pulse oximetry waveform analysis, specifically focused on detection of coarctation of the aorta. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00775-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227302PMC

Electrochemical modeling and evaluation for textile electrodes to skin.

Biomed Eng Online 2020 May 11;19(1):30. Epub 2020 May 11.

Key Laboratory for Biomedical Engineering of Ministry of Education, Engineering Research Center of EMR and Intelligent Expert System, Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, 310027, China.

Background: With the development of wearable health-monitoring technologies, a variety of textile electrodes have been produced and applied by researchers. However, there are no universal and effective methods even testing platforms for evaluating the skin-electrode electrochemical interface for textile electrodes because different human bodies have different skin characteristics.

Methods: An electrochemical modeling and evaluation for textile electrodes to skin was proposed, and two electrochemical evaluation platforms (EEP) were set up based on two simulated skin models (SSM). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00772-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216351PMC
May 2020
1.427 Impact Factor

Postural control learning dynamics in Parkinson's disease: early improvement with plateau in stability, and continuous progression in flexibility and mobility.

Biomed Eng Online 2020 May 11;19(1):29. Epub 2020 May 11.

Mechanical Engineering Department, Sharif University of Technology, Tehran, Iran.

Background: Balance training improves postural control in Parkinson's disease (PD). However, a systematic approach for the development of individualized, optimal training programs is still lacking, as the learning dynamics of the postural control in PD, over a training program, are poorly understood.

Objectives: We investigated the learning dynamics of the postural control in PD, during a balance-training program, in terms of the clinical, posturographic, and novel model-based measures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00776-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216342PMC

Reaching exercise for chronic paretic upper extremity after stroke using a novel rehabilitation robot with arm-weight support and concomitant electrical stimulation and vibration: before-and-after feasibility trial.

Biomed Eng Online 2020 May 6;19(1):28. Epub 2020 May 6.

Department of Rehabilitation and Physical Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan.

Background: Our group developed a rehabilitation robot to assist with repetitive, active reaching movement of a paretic upper extremity. The robot is equipped with a servo motor-controlled arm-weight support and works in conjunction with neuromuscular electrical stimulation and vibratory stimulation to facilitate agonist-muscle contraction. In this before-and-after pilot study, we assessed the feasibility of applying the robot to improve motor control and function of the hemiparetic upper extremity in patients who suffered chronic stroke. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00774-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203976PMC

Atrial fibrillation source area probability mapping using electrogram patterns of multipole catheters.

Biomed Eng Online 2020 May 5;19(1):27. Epub 2020 May 5.

Department of Computer and Electrical Engineering, Florida Atlantic University, Boca Raton, FL, USA.

Background: Catheter ablation therapy involving isolation of pulmonary veins (PVs) from the left atrium is performed to terminate atrial fibrillation (AF). Unfortunately, standalone PV isolation procedure has shown to be a suboptimal success with AF continuation or recurrence. One reason, especially in patients with persistent or high-burden paroxysmal AF, is known to be due to the formation of repeating-pattern AF sources with a meandering core inside the atria. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00769-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201756PMC

Risk and reward: extending stochastic glycaemic control intervals to reduce workload.

Biomed Eng Online 2020 Apr 29;19(1):26. Epub 2020 Apr 29.

Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.

Background: STAR is a model-based, personalised, risk-based dosing approach for glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly all patients, using 1-3 hourly measurement and intervention intervals. However, the average 11-12 measurements per day required can be a clinical burden in many intensive care units. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00771-6DOI Listing

Kinect and wearable inertial sensors for motor rehabilitation programs at home: state of the art and an experimental comparison.

Biomed Eng Online 2020 Apr 23;19(1):25. Epub 2020 Apr 23.

E3DA, Fondazione Bruno Kessler (FBK), Trento, Italy.

Background: Emerging sensing and communication technologies are contributing to the development of many motor rehabilitation programs outside the standard healthcare facilities. Nowadays, motor rehabilitation exercises can be easily performed and monitored even at home by a variety of motion-tracking systems. These are cheap, reliable, easy-to-use, and allow also remote configuration and control of the rehabilitation programs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00762-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178588PMC

Segmentation of finger tendon and synovial sheath in ultrasound image using deep convolutional neural network.

Biomed Eng Online 2020 Apr 22;19(1):24. Epub 2020 Apr 22.

Department of Computer Science and Information Engineering, 1 University Road, Tainan, 701, Taiwan.

Background: Trigger finger is a common hand disease, which is caused by a mismatch in diameter between the tendon and the pulley. Ultrasound images are typically used to diagnose this disease, which are also used to guide surgical treatment. However, background noise and unclear tissue boundaries in the images increase the difficulty of the process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00768-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178953PMC
April 2020
1.427 Impact Factor

A probabilistic approach for calibration time reduction in hybrid EEG-fTCD brain-computer interfaces.

Biomed Eng Online 2020 Apr 16;19(1):23. Epub 2020 Apr 16.

Electrical and Computer Engineering Department, University of Pittsburgh, Pittsburgh, PA, USA.

Background: Generally, brain-computer interfaces (BCIs) require calibration before usage to ensure efficient performance. Therefore, each BCI user has to attend a certain number of calibration sessions to be able to use the system. However, such calibration requirements may be difficult to fulfill especially for patients with disabilities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00765-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164278PMC

Identification of arthropathy and myopathy of the temporomandibular syndrome by biomechanical facial features.

Biomed Eng Online 2020 Apr 15;19(1):22. Epub 2020 Apr 15.

Laboratory of Biomedical Engineering, Faculty of Electrical Engineering, Federal University of Uberlandia, Av. Joao Naves de Avila, 2121, Uberlandia, 38408-100, Brazil.

Background: Temporomandibular disorders (TMDs) are pathological conditions affecting the temporomandibular joint and/or masticatory muscles. The current diagnosis of TMDs is complex and multi-factorial, including questionnaires, medical testing and the use of diagnostic methods, such as computed tomography and magnetic resonance imaging. The evaluation, like the mandibular range of motion, needs the experience of the professional in the field and as such, there is a probability of human error when diagnosing TMD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00764-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161015PMC
April 2020
1.427 Impact Factor

Microaneurysms detection in color fundus images using machine learning based on directional local contrast.

Biomed Eng Online 2020 Apr 15;19(1):21. Epub 2020 Apr 15.

Research Center of Intelligent Healthcare, Faculty of Health and Life Science, Coventry University, Coventry, CV1 5RW, UK.

Background: As one of the major complications of diabetes, diabetic retinopathy (DR) is a leading cause of visual impairment and blindness due to delayed diagnosis and intervention. Microaneurysms appear as the earliest symptom of DR. Accurate and reliable detection of microaneurysms in color fundus images has great importance for DR screening. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00766-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161183PMC

Machine learning applied to retinal image processing for glaucoma detection: review and perspective.

Biomed Eng Online 2020 Apr 15;19(1):20. Epub 2020 Apr 15.

Laboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, Brazil.

Introduction: This is a systematic review on the main algorithms using machine learning (ML) in retinal image processing for glaucoma diagnosis and detection. ML has proven to be a significant tool for the development of computer aided technology. Furthermore, secondary research has been widely conducted over the years for ophthalmologists. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00767-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160894PMC

A real-time system for selectively sensing and pacing the His-bundle during sinus rhythm and ventricular fibrillation.

Biomed Eng Online 2020 Apr 10;19(1):19. Epub 2020 Apr 10.

Department of Biomedical Engineering, The University of Utah, Salt Lake City, UT, 84112, USA.

Background: The His-Purkinje (HP) system provides a pathway for the time-synchronous contraction of the heart. His bundle (HB) of the HP system is gaining relevance as a pacing site for treating non-reversible bradyarrhythmia despite limited availability of tools to identify the HB. In this paper, we describe a real-time stimulation and recording system (rt-SRS) to investigate using multi-electrode techniques to identify and selectively pace the HB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00763-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146996PMC
April 2020
1.427 Impact Factor

Remineralization of dentin slices using casein phosphopeptide-amorphous calcium phosphate combined with sodium tripolyphosphate.

Biomed Eng Online 2020 Apr 3;19(1):18. Epub 2020 Apr 3.

Institute of Stomatology, Nanjing Medical University, 136 Hanzhong Road, Nanjing, 210029, Jiangsu, China.

Background: The remineralization approach mechanically occludes the exposed dentinal tubules mechanically, reduces the permeability of dentinal tubules and eliminates the symptoms of dentin hypersensitivity. The aim of the present study was to investigate the remineralization of demineralized dentin slices using CPP-ACP combined with TPP, and the research hypothesis was that CPP-ACP combined with TPP could result in extrafibrillar and intrafibrillar remineralization of dentin.

Methods: Demineralized dentin slices were prepared and randomly divided into the following groups: A (the CPP-ACP group), B (the CPP-ACP + TPP combination group), C (the artificial saliva group), D (the negative control group), and E (the positive control group). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0756-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119276PMC

Review of automatic continuous distraction osteogenesis devices for mandibular reconstruction applications.

Biomed Eng Online 2020 Apr 1;19(1):17. Epub 2020 Apr 1.

Precision Engineering Laboratory, Nelson Mandela University, Port Elizabeth, South Africa.

Distraction osteogenesis (DO) is an emerging method for bone tissue reconstruction. In oral and maxillofacial reconstruction applications, DO is playing an important role as a technique without the need of bone graft. In addition, in a DO treatment procedure, a superior outcome could be achieved compared to conventional reconstruction techniques. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00761-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110677PMC
April 2020
1.427 Impact Factor

Correction to: Detecting focal cortical dysplasia lesions from FLAIR-negative images based on cortical thickness.

Biomed Eng Online 2020 03 17;19(1):16. Epub 2020 Mar 17.

Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China.

It was highlighted that the original article [1] contained an error in the Quantitative evaluation of Methods. A bracket was misplaced in the formula. This Correction article shows the incorrect and correct formula. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-00760-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079367PMC

Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats.

Biomed Eng Online 2020 Mar 6;19(1):15. Epub 2020 Mar 6.

Department of Cardiology, Qing Zhou Traditional Chinese Hospital, No. 2727, Haidai Middle Road, Weifang, 262500, Shandong, China.

Background: Previous in vitro studies demonstrated that suppression of microRNAs might protect cardiomyocytes and neurons against oxygen-glucose deprivation and reoxygenation (OGD/R)-induced cell apoptosis. However, whether the protective effect of miR-153-inhibition on cardiomyocytes can be observed in the animal model is unknown. We aimed to address this question using a rat model of ischemia-reperfusion (I/R). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0759-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059292PMC

Low-cost equipment for the evaluation of reach and grasp in post-stroke individuals: a pilot study.

Biomed Eng Online 2020 Mar 4;19(1):14. Epub 2020 Mar 4.

School of Health Sciences, Federal University of Rio Grande do Norte (UFRN), Santa Cruz, RN, Brazil.

Background: Reach-grasp movements are motor components commonly affected after stroke and directly related to the independence of these individuals. Evaluations of these activities can be performed using clinical instruments and assessed by detailed and costly kinematic analyses. The aim of this study was to develop an analysis of reach-grasp movements in post-stroke patients using a simple, inexpensive, and manageable instrument. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0758-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057550PMC

Detecting focal cortical dysplasia lesions from FLAIR-negative images based on cortical thickness.

Biomed Eng Online 2020 Feb 22;19(1):13. Epub 2020 Feb 22.

Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China.

Background: Focal cortical dysplasia (FCD) is a neuronal migration disorder and is a major cause of drug-resistant epilepsy. However, many focal abnormalities remain undetected during routine visual inspection, and many patients with histologically confirmed FCD have normal fluid-attenuated inversion recovery (FLAIR-negative) images. The aim of this study was to quantitatively evaluate the changes in cortical thickness with magnetic resonance (MR) imaging of patients to identify FCD lesions from FLAIR-negative images. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0757-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036191PMC
February 2020

Data anomalies and apparent reporting errors in 'Randomized controlled trial testing weight loss and abdominal obesity outcomes of moxibustion'.

Biomed Eng Online 2020 Feb 18;19(1):11. Epub 2020 Feb 18.

Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, 1025 E 7th St, Bloomington, IN, 47405, USA.

Randomized Controlled Trials (RCTs) are the best method to determine causal effects for treatments if they are well done and well reported. Good evidence about proposed treatments for obesity is needed, and Hsieh et al. (Biomed Eng Online 17:149, 2018) are to be commended for putting moxibustion to the test. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0753-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029490PMC
February 2020

In vitro antibacterial activity and cytocompatibility of magnesium-incorporated poly(lactide-co-glycolic acid) scaffolds.

Biomed Eng Online 2020 Feb 18;19(1):12. Epub 2020 Feb 18.

Department of Bone and Joint Surgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, Shanxi, China.

Background: Bone defects are often combined with the risk of infection in the clinic, and artificial bone substitutes are often implanted to repair the defective bone. However, the implant materials are carriers for bacterial growth, and biofilm can form on the implant surface, which is difficult to eliminate using antibiotics and the host immune system. Magnesium (Mg) was previously reported to possess antibacterial potential. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0755-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029519PMC
February 2020

Epileptic seizure classifications using empirical mode decomposition and its derivative.

Biomed Eng Online 2020 Feb 14;19(1):10. Epub 2020 Feb 14.

Department of Electrical and Electronics Engineering, Faculty of Engineering, Izmir University of Economics, Balcova, Izmir, Turkey.

Background: Epilepsy is one of the most common neurological disorders associated with disruption of brain activity. In the classification and detection of epileptic seizures, electroencephalography (EEG) measurements, which record the electrical activities of the brain, are frequently used. Empirical mode decomposition (EMD) and its derivative, ensemble EMD (EEMD) are recently developed methods used to decompose non-stationary and nonlinear signals such as EEG into a finite number of oscillations called intrinsic mode functions (IMFs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0754-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023773PMC
February 2020

Organ-on-a-chip: recent breakthroughs and future prospects.

Biomed Eng Online 2020 Feb 12;19(1). Epub 2020 Feb 12.

Materials Genome Institute, Shanghai University, Shanghai, 200444, China.

The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a physiological organ biomimetic system built on a microfluidic chip. Through a combination of cell biology, engineering, and biomaterial technology, the microenvironment of the chip simulates that of the organ in terms of tissue interfaces and mechanical stimulation. This reflects the structural and functional characteristics of human tissue and can predict response to an array of stimuli including drug responses and environmental effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0752-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017614PMC
February 2020

Effects of dynamic radial tensile stress on fibrocartilage differentiation of bone marrow mesenchymal stem cells.

Biomed Eng Online 2020 Feb 5;19(1). Epub 2020 Feb 5.

Key Lab of Oral Diseases of Gansu Province, Northwest Minzu University, Lanzhou, People's Republic of China.

Background: Uniaxial/biaxial tensile stress has been employed to induce chondrocyte differentiation of mesenchymal stem cells. However, the effects of radial tensile stimuli on differentiation of MSCs into fibrocartilage remain unclear.

Results: It was found that induced bone marrow mesenchymal stem cells (BMSCs) were not only similar to TMJ disc cells in morphology, but also could synthesize type I collagen (Col I), a small amount of type II collagen (Col II) and glycosaminoglycans (GAGs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0751-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003351PMC
February 2020

The sensitivity of different methods for detecting abnormalities in auditory nerve function.

Biomed Eng Online 2020 Feb 3;19(1). Epub 2020 Feb 3.

Department of Otolaryngology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China.

Background: Cochlear implants (CIs) have become important for the treatment of severe-to-profound sensorineural hearing loss (SNHL). Meanwhile, electrically evoked compound action potentials (ECAPs) and electrically evoked auditory brainstem responses (EABRs), which can be examined and evaluated with minimal patient cooperation, have become more reliable for tone measurement and speech recognition postoperatively. However, few studies have compared the electrophysiological characteristics of the auditory nerve using ECAPs and EABRs under different functional states of the auditory nerve (FSANs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0750-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998811PMC
February 2020
1.427 Impact Factor

Retraction Note to: Randomized controlled trial testing weight loss and abdominal obesity outcomes of moxibustion.

Biomed Eng Online 2020 01 24;19(1). Epub 2020 Jan 24.

School of Nursing, University of Maryland School of Nursing, Baltimore, MD, USA.

The Editors-in-Chief have retracted this article [1] because, after publication, concerns were raised regarding the study design and statistical analysis. Post-publication review has confirmed firstly that within-group changes were highlighted rather than between-group differences as appropriate for a randomized trial, and secondly that there are baseline differences between the groups that exist despite randomization for which analyses were not controlled. The data reported in this article are therefore unreliable. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0749-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979344PMC
January 2020

Elaboration of a multimodal MRI-based radiomics signature for the preoperative prediction of the histological subtype in patients with non-small-cell lung cancer.

Biomed Eng Online 2020 Jan 21;19(1). Epub 2020 Jan 21.

Department of Radiology, Xijing Hospital, Fourth Military Medical University, No. 169 Changle West Road, Xi'an, 710032, Shaanxi, People's Republic of China.

Background: Non-invasive discrimination between lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) subtypes of non-small-cell lung cancer (NSCLC) could be very beneficial to the patients unfit for the invasive diagnostic procedures. The aim of this study was to investigate the feasibility of utilizing the multimodal magnetic resonance imaging (MRI) radiomics and clinical features in classifying NSCLC. This retrospective study involved 148 eligible patients with postoperative pathologically confirmed NSCLC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0744-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975040PMC
January 2020
1.427 Impact Factor

Inter-site harmonization based on dual generative adversarial networks for diffusion tensor imaging: application to neonatal white matter development.

Biomed Eng Online 2020 Jan 15;19(1). Epub 2020 Jan 15.

Department of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.

Background: Site-specific variations are challenges for pooling analyses in multi-center studies. This work aims to propose an inter-site harmonization method based on dual generative adversarial networks (GANs) for diffusion tensor imaging (DTI) derived metrics on neonatal brains.

Results: DTI-derived metrics (fractional anisotropy, FA; mean diffusivity, MD) are obtained on age-matched neonates without magnetic resonance imaging (MRI) abnormalities: 42 neonates from site 1 and 42 neonates from site 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0748-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964111PMC
January 2020
1.427 Impact Factor

Gated recurrent unit-based heart sound analysis for heart failure screening.

Biomed Eng Online 2020 Jan 13;19(1). Epub 2020 Jan 13.

Key Laboratory of Biorheology Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China.

Background: Heart failure (HF) is a type of cardiovascular disease caused by abnormal cardiac structure and function. Early screening of HF has important implication for treatment in a timely manner. Heart sound (HS) conveys relevant information related to HF; this study is therefore based on the analysis of HS signals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-020-0747-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958660PMC
January 2020

Multifactor consciousness level assessment of participants with acquired brain injuries employing human-computer interfaces.

Biomed Eng Online 2020 Jan 10;19(1). Epub 2020 Jan 10.

Multimedia Systems Department, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, Gdańsk, Poland.

Background: A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the assessment of such patients' state employing future generation computers extended with advanced human-machine interfaces. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0746-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954635PMC
January 2020

Optimization of virtual and real registration technology based on augmented reality in a surgical navigation system.

Biomed Eng Online 2020 Jan 8;19(1). Epub 2020 Jan 8.

School of Mechanical and Electrical Engineering, Soochow University, Suzhou, 215006, China.

Background: The traditional navigation interface was intended only for two-dimensional observation by doctors; thus, this interface does not display the total spatial information for the lesion area. Surgical navigation systems have become essential tools that enable for doctors to accurately and safely perform complex operations. The image navigation interface is separated from the operating area, and the doctor needs to switch the field of vision between the screen and the patient's lesion area. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0745-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950982PMC
January 2020

Analyzing brain structural differences associated with categories of blood pressure in adults using empirical kernel mapping-based kernel ELM.

Biomed Eng Online 2019 Dec 27;18(1):124. Epub 2019 Dec 27.

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, Suzhou, Jiangsu, China.

Background: Hypertension increases the risk of angiocardiopathy and cognitive disorder. Blood pressure has four categories: normal, elevated, hypertension stage 1 and hypertension stage 2. The quantitative analysis of hypertension helps determine disease status, prognosis assessment, guidance and management, but is not well studied in the framework of machine learning. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0740-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935092PMC
December 2019

Molecular dynamics simulation of reversible electroporation with Martini force field.

Authors:
Cheng Zhou Kefu Liu

Biomed Eng Online 2019 Dec 26;18(1):123. Epub 2019 Dec 26.

Department of Light Sources & Illuminating Engineering, Fudan University, 220 Handan Road, Yangpu District, Shanghai, 200433, China.

Background: After the discovery of membrane-reversible electroporation decades ago, the procedure has been used extensively in biology, biotechnology and medicine. The research on the basic mechanism has increasingly attracted attention. Although most research has focused on models that consider all atomic and molecular interactions and much atomic-level information can be obtained, the huge computational demand limits the models to simulations of only a few nanometers on the spatial scale and a few nanoseconds on the time scale. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0743-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933919PMC
December 2019

Study on the biomechanical responses of the loaded bone in macroscale and mesoscale by multiscale poroelastic FE analysis.

Biomed Eng Online 2019 Dec 23;18(1):122. Epub 2019 Dec 23.

College of Biomedical Engineering, Shanxi Key Lab. of Material Strength, College of Biomedical Engineering & Structural Impact, Taiyuan University of Technology, Taiyuan, 030024, Shanxi, China.

Background: Bone is a hierarchically structured composite material, and different hierarchical levels exhibit diverse material properties and functions. The stress and strain distribution and fluid flow in bone play an important role in the realization of mechanotransduction and bone remodeling.

Methods: To investigate the mechanotransduction and fluid behaviors in loaded bone, a multiscale method was developed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0741-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929473PMC
December 2019

Ultrasonic liver steatosis quantification by a learning-based acoustic model from a novel shear wave sequence.

Biomed Eng Online 2019 Dec 21;18(1):121. Epub 2019 Dec 21.

Department of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.

Background: An efficient and accurate approach to quantify the steatosis extent of liver is important for clinical practice. For the purpose, we propose a specific designed ultrasound shear wave sequence to estimate ultrasonic and shear wave physical parameters. The utilization of the estimated quantitative parameters is then studied. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0742-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925885PMC
December 2019

Towards the automation of early-stage human embryo development detection.

Biomed Eng Online 2019 Dec 12;18(1):120. Epub 2019 Dec 12.

Department of Automation, Kaunas University of Technology, 51367, Kaunas, Lithuania.

Background: Infertility and subfertility affect a significant proportion of humanity. Assisted reproductive technology has been proven capable of alleviating infertility issues. In vitro fertilisation is one such option whose success is highly dependent on the selection of a high-quality embryo for transfer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0738-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909649PMC
December 2019

Effect of strontium-containing on the properties of Mg-doped wollastonite bioceramic scaffolds.

Biomed Eng Online 2019 Dec 11;18(1):119. Epub 2019 Dec 11.

Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.

Background: Bone scaffold is one of the most effective methods to treat bone defect. The ideal scaffold of bone tissue should not only provide space for bone tissue growth, but also have sufficient mechanical strength to support the bone defect area. Moreover, the scaffold should provide a customized size or shape for the patient's bone defect. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0739-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907205PMC
December 2019

A comparative analysis of health surveillance strategies for administrative video display terminal employees.

Biomed Eng Online 2019 Dec 11;18(1):118. Epub 2019 Dec 11.

Department of Natural Resources and Environmental Engineering, University of Vigo, Vigo, Spain.

Background: The objective of this study was to develop a strategy to optimize medical health surveillance protocols for administrative employees using video display terminals (VDTs). A total of 2453 medical examinations were analysed for VDT users in various sectors. From these data, using Bayesian statistics we inferred which factors were most relevant to medical diagnosis of the main disorders affecting VDT users. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0737-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907276PMC
December 2019

Combining dual-tree complex wavelets and multiresolution in iterative CT reconstruction with application to metal artifact reduction.

Biomed Eng Online 2019 Dec 5;18(1):116. Epub 2019 Dec 5.

Laboratory of Mathematics, Tampere University, Korkeakoulunkatu 3, 33720, Tampere, Finland.

Background: This paper investigates the benefits of data filtering via complex dual wavelet transform for metal artifact reduction (MAR). The advantage of using complex dual wavelet basis for MAR was studied on simulated dental computed tomography (CT) data for its efficiency in terms of noise suppression and removal of secondary artifacts. Dual-tree complex wavelet transform (DT-CWT) was selected due to its enhanced directional analysis of image details compared to the ordinary wavelet transform. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0727-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896265PMC
December 2019

A current-mode system to self-measure temperature on implantable optoelectronics.

Biomed Eng Online 2019 Dec 5;18(1):117. Epub 2019 Dec 5.

School of Engineering, Newcastle University, Newcastle, NE1 7RU, UK.

Background: One of the major concerns in implantable optoelectronics is the heat generated by emitters such as light emitting diodes (LEDs). Such devices typically produce more heat than light, whereas medical regulations state that the surface temperature change of medical implants must stay below + 2 °C. The LED's reverse current can be employed as a temperature-sensitive parameter to measure the temperature change at the implant's surface, and thus, monitor temperature rises. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0736-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896326PMC
December 2019

Micromechanical modeling of the contact stiffness of an osseointegrated bone-implant interface.

Biomed Eng Online 2019 Dec 3;18(1):114. Epub 2019 Dec 3.

CNRS, Laboratoire Modélisation et Simulation Multi Echelle, MSME, UMR CNRS 8208, 61 Avenue du Général de Gaulle, 94010, Créteil, France.

Background: The surgical success of cementless implants is determined by the evolution of the biomechanical properties of the bone-implant interface (BII). One difficulty to model the biomechanical behavior of the BII comes from the implant surface roughness and from the partial contact between bone tissue and the implant. The determination of the constitutive law of the BII would be of interest in the context of implant finite element (FE) modeling to take into account the imperfect characteristics of the BII. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12938-019-0733-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889538PMC
December 2019