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    27 results match your criteria BioMagnetic Research and Technology [Journal]

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    Size dependent heat generation of magnetite nanoparticles under AC magnetic field for cancer therapy.
    Biomagn Res Technol 2008 Oct 20;6. Epub 2008 Oct 20.
    Department of Biotechnology, School of Engineering, Nagoya University, Furo-cho, Nagoya 464-8603, Japan.
    Background: We have developed magnetic cationic liposomes (MCLs) that contained magnetic nanoparticles as heating mediator for applying them to local hyperthermia. The heating performance of the MCLs is significantly affected by the property of the incorporated magnetite nanoparticles. We estimated heating capacity of magnetite nanoparticles by measuring its specific absorption rate (SAR) against irradiation of the alternating magnetic field (AMF). Read More

    Effects of electromagnetic fields of low frequency and low intensity on rat metabolism.
    Biomagn Res Technol 2008 Apr 1;6. Epub 2008 Apr 1.
    1Department of Veterinary Clinical Sciences, University of Padua, Agripolis, Viale dell'Università 16, 35020 Legnaro, Padua, Italy.
    A series of experiments on rats have been performed, to study the effects of long time (50 days) exposure to electromagnetic fields of extremely low frequency (ELF, i.e. less than 100 Hz) and amplitude (non thermal), testing whether the metabolic processes would be affected. Read More

    Hyperthermic treatment of DMBA-induced rat mammary cancer using magnetic nanoparticles.
    Biomagn Res Technol 2008 Feb 25;6. Epub 2008 Feb 25.
    1Nanotherapy Co, Ltd, 19-11, Kikui 2-chome, Nishi-ku, Nagoya 451-0044, Japan.
    Background: We have developed magnetite cationic liposomes (MCLs) and applied them as a mediator of local hyperthermia. MCLs can generate heat under an alternating magnetic field (AMF). In this study, the in vivo effect of hyperthermia mediated by MCLs was examined using 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary cancer as a spontaneous cancer model. Read More

    Action of combined magnetic fields on aqueous solution of glutamic acid: the further development of investigations.
    Biomagn Res Technol 2008 Jan 25;6. Epub 2008 Jan 25.
    Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy.
    In the present work the results of the known investigation of the influence of combined static (40 microT) and alternating (amplitude of 40 nT) parallel magnetic fields on the current through the aqueous solution of glutamic acid, were successfully replicated. Fourteen experiments were carried out by the application of the combined magnetic fields to the solution placed into a Plexiglas reaction vessel at application of static voltage to golden electrodes placed into the solution. Six experiments were carried out by the application of the combined magnetic fields to the solution placed in a Plexiglas reaction vessel, without electrodes, within an electric field, generated by means of a capacitor at the voltage of 27 mV. Read More

    Investigating the effects of external fields polarization on the coupling of pure magnetic waves in the human body in very low frequencies.
    Biomagn Res Technol 2007 May 15;5. Epub 2007 May 15.
    Laboratory of Electromagnetics and Acoustics, Ecole Polytechnique Fédérate de Lausanne, Switzerland.
    In this paper we studied the effects of external fields' polarization on the coupling of pure magnetic fields into human body. Finite Difference Time Domain (FDTD) method is used to calculate the current densities induced in a 1 cm resolution anatomically based model with proper tissue conductivities. Twenty different tissues have been considered in this investigation and scaled FDTD technique is used to convert the results of computer code run in 15 MHz to low frequencies which are encountered in the vicinity of industrial induction heating and melting devices. Read More

    Process and formulation variables in the preparation of injectable and biodegradable magnetic microspheres.
    Biomagn Res Technol 2007 Apr 4;5. Epub 2007 Apr 4.
    Faculty of Pharmaceutical Sciences, The University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada.
    The aim of this study was to prepare biodegradable sustained release magnetite microspheres sized between 1 to 2 microm. The microspheres with or without magnetic materials were prepared by a W/O/W double emulsion solvent evaporation technique using poly(lactide-co-glycolide) (PLGA) as the biodegradable matrix forming polymer. Effects of manufacturing and formulation variables on particle size were investigated with non-magnetic microspheres. Read More

    Magnetic characterization of superparamagnetic nanoparticles pulled through model membranes.
    Biomagn Res Technol 2007 Jan 4;5. Epub 2007 Jan 4.
    Department of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, 940 S,L, Young Blvd,, Oklahoma City, OK 73104-0505, USA.
    Background: To quantitatively compare in-vitro and in vivo membrane transport studies of targeted delivery, one needs characterization of the magnetically-induced mobility of superparamagnetic iron oxide nanoparticles (SPION). Flux densities, gradients, and nanoparticle properties were measured in order to quantify the magnetic force on the SPION in both an artificial cochlear round window membrane (RWM) model and the guinea pig RWM.

    Methods: Three-dimensional maps were created for flux density and magnetic gradient produced by a 24-well casing of 4. Read More

    High magnetic field induced changes of gene expression in arabidopsis.
    Biomagn Res Technol 2006 Dec 22;4. Epub 2006 Dec 22.
    Department of Horticultural Sciences and The Biotechnology Program, University of Florida, Gainesville, FL 32611-0690, USA.
    Background: High magnetic fields are becoming increasingly prevalent components of non-invasive, biomedical imaging tools (such as MRI), thus, an understanding of the molecular impacts associated with these field strengths in biological systems is of central importance. The biological impact of magnetic field strengths up to 30 Tesla were investigated in this study through the use of transgenic Arabidopsis plants engineered with a stress response gene consisting of the alcohol dehydrogenase (Adh) gene promoter driving the beta-glucuronidase (GUS) gene reporter.

    Methods: Magnetic field induced Adh/GUS activity was evaluated with histochemical staining to assess tissue specific expression and distribution, and with quantitative, spectrofluometric assays to measure degree of activation. Read More

    Analytical and preparative applications of magnetic split-flow thin fractionation on several ion-labeled red blood cells.
    Biomagn Res Technol 2006 Dec 19;4. Epub 2006 Dec 19.
    School of Applied Chemistry, Chung Shan Medical University, 110, Sec 1, Chien-Kuo N. Road, Taichung 402, Taiwan.
    Background: Magnetic Split-flow thin (SPLITT) fractionation is a newly developed technique for separating magnetically susceptible particles. Particles with different field-induced velocities can be separated into two fractions by adjusting applied magnetic forces and flow-rates at inlets and outlets.

    Methods: Magnetic particles, Dynabeads, were used to test this new approach of field-induced velocity for susceptibility determination using magnetic SF at different magnetic field intensities. Read More

    Pseudo current density maps of electrophysiological heart, nerve or brain function and their physical basis.
    Biomagn Res Technol 2006 Oct 13;4. Epub 2006 Oct 13.
    Physikalisch-Technische Bundesanstalt, Berlin, Germany.
    Background: In recent years the visualization of biomagnetic measurement data by so-called pseudo current density maps or Hosaka-Cohen (HC) transformations became popular.

    Methods: The physical basis of these intuitive maps is clarified by means of analytically solvable problems.

    Results: Examples in magnetocardiography, magnetoencephalography and magnetoneurography demonstrate the usefulness of this method. Read More

    Motion and twisting of magnetic particles ingested by alveolar macrophages in the human lung: effect of smoking and disease.
    Biomagn Res Technol 2006 May 15;4. Epub 2006 May 15.
    GSF National Research Center for Environment and Health, Clinical Research Group Inflammatory Lung Diseases and Institute for Inhalation Biology, Gauting, Germany.
    Background: Magnetic microparticles being ingested by alveolar macrophages can be used as a monitor for intracellular phagosome motions and cytoskeletal mechanical properties. These studies can be performed in the human lung after voluntary inhalation. The influence of cigarette smoking and lung diseases on cytoskeleton dependent functions was studied. Read More

    Differentiation of myomas by means of biomagnetic and doppler findings.
    Biomagn Res Technol 2006 Apr 3;4. Epub 2006 Apr 3.
    Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, University Campus, Alexandroupolis, 68100, Greece.
    Aim: To elucidate the hemodynamics of the uterine artery myomas by use of Doppler ultrasound and biomagnetic measurements.

    Method: Twenty-four women were included in the study. Sixteen of them were characterised with large myomas whereas 8 of them with small ones. Read More

    Nonlinear analysis of biomagnetic signals recorded from uterine myomas.
    Biomagn Res Technol 2006 Mar 30;4. Epub 2006 Mar 30.
    Lab of Medical Physics and Department of Obstetrics and Gynaecology, Medical School, Democritus University of Thrace, University Campus, Alexandroupolis, Greece.
    Objective: To determine if there is any non-linearity in the biomagnetic recordings of uterine myomas and to find any differences that may be present in the mechanisms underlying their signal dynamics.

    Methods: Twenty-four women were included in the study. Sixteen of them were characterised with large myomas and 8 with small ones. Read More

    Growth of etiolated barley plants in weak static and 50 Hz electromagnetic fields tuned to calcium ion cyclotron resonance.
    Biomagn Res Technol 2006 Feb 3;4. Epub 2006 Feb 3.
    Department Biologie I Universität München - Bereich Botanik, Menzingerstr, 67, D-80638 München, Germany.
    Background: The effects of weak magnetic and electromagnetic fields in biology have been intensively studied on animals, microorganisms and humans, but comparably less on plants. Perception mechanisms were attributed originally to ferrimagnetism, but later discoveries required additional explanations like the "radical pair mechanism" and the "Ion cyclotron resonance" (ICR), primarily considered by Liboff. The latter predicts effects by small ions involved in biological processes, that occur in definite frequency- and intensity ranges ("windows") of simultaneously impacting magnetic and electromagnetic fields related by a linear equation, which meanwhile is proven by a number of in vivo and in vitro experiments. Read More

    Cortex reorganization of Xenopus laevis eggs in strong static magnetic fields.
    Biomagn Res Technol 2005 Dec 13;3. Epub 2005 Dec 13.
    Fraunhofer Institute for Biomedical Engineering (IBMT), St. Ingbert, Germany.
    Observations of magnetic field effects on biological systems have often been contradictory. For amphibian eggs, a review of the available literature suggests that part of the discrepancies might be resolved by considering a previously neglected parameter for morphological alterations induced by magnetic fields--the jelly layers that normally surround the egg and are often removed in laboratory studies for easier cell handling. To experimentally test this hypothesis, we observed the morphology of fertilizable Xenopus laevis eggs with and without jelly coat that were subjected to static magnetic fields of up to 9. Read More

    Activity of glucose oxidase functionalized onto magnetic nanoparticles.
    Biomagn Res Technol 2005 Mar 11;3(1). Epub 2005 Mar 11.
    Department of Agricultural and Biological Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
    BACKGROUND: Magnetic nanoparticles have been significantly used for coupling with biomolecules, due to their unique properties. METHODS: Magnetic nanoparticles were synthesized by thermal co-precipitation of ferric and ferrous chloride using two different base solutions. Glucose oxidase was bound to the particles by direct attachment via carbodiimide activation or by thiophene acetylation of magnetic nanoparticles. Read More

    Characterisation of weak magnetic field effects in an aqueous glutamic acid solution by nonlinear dielectric spectroscopy and voltammetry.
    Biomagn Res Technol 2004 Nov 30;2(1). Epub 2004 Nov 30.
    Department Biologie 1 Universität München-Bereich Botanik, Menzingerstr, 67, D-80638 München, Germany.
    BACKGROUND: Previous reports indicate altered metabolism and enzyme kinetics for various organisms, as well as changes of neuronal functions and behaviour of higher animals, when they were exposed to specific combinations of weak static and alternating low frequency electromagnetic fields. Field strengths and frequencies, as well as properties of involved ions were related by a linear equation, known as the formula of ion cyclotron resonance (ICR, abbreviation mentioned first by Liboff). Under certain conditions already a aqueous solution of the amino acid and neurotransmitter glutamate shows this effect. Read More

    Magnetic techniques for the isolation and purification of proteins and peptides.
    Biomagn Res Technol 2004 Nov 26;2(1). Epub 2004 Nov 26.
    Laboratory of Biochemistry and Microbiology, Institute of Landscape Ecology, Academy of Sciences, Na Sadkach 7, 370 05 Ceske Budejovice, Czech Republic.
    Isolation and separation of specific molecules is used in almost all areas of biosciences and biotechnology. Diverse procedures can be used to achieve this goal. Recently, increased attention has been paid to the development and application of magnetic separation techniques, which employ small magnetic particles. Read More

    Simultaneous suppression of disturbing fields and localization of magnetic markers by means of multipole expansion.
    Biomagn Res Technol 2004 Sep 1;2(1). Epub 2004 Sep 1.
    Biomagnetic Center, Department of Neurology, Friedrich Schiller University Jena, Germany.
    BACKGROUND: Magnetically marked capsules serve for the analysis of peristalsis and throughput times within the intestinal tract. Moreover, they can be used for the targeted disposal of drugs. The capsules get localized in time by field measurements with a superconducting quantum interference device (SQUID) magnetometer array. Read More

    Performance of dye-affinity beads for aluminium removal in magnetically stabilized fluidized bed.
    Biomagn Res Technol 2004 Aug 26;2(1). Epub 2004 Aug 26.
    Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara, Turkey.
    BACKGROUND: Aluminum has recently been recognized as a causative agent in dialysis encephalopathy, osteodystrophy, and microcytic anemia occurring in patients with chronic renal failure who undergo long-term hemodialysis. Only a small amount of Al(III) in dialysis solutions may give rise to these disorders. METHODS: Magnetic poly(2-hydroxyethyl methacrylate) (mPHEMA) beads in the size range of 80-120 microm were produced by free radical co-polymerization of HEMA and ethylene dimethacrylate (EDMA) in the presence of magnetite particles (Fe3O4). Read More

    Physically synthesized Ni-Cu nanoparticles for magnetic hyperthermia.
    Biomagn Res Technol 2004 May 8;2(1). Epub 2004 May 8.
    Center for Nanomagnetics and Biotechnology Florida State University Tallahassee, Florida 32310 USA.
    BACKGROUND: In this paper, a physical method to prepare copper-nickel alloy particles in the sub-micron range for possible self controlled magnetic hyperthermia treatment of cancer is described. It is reported that an increase in tumor temperature decreases the tumor resistance to chemo- and radiation therapies. Self controlled heating at the tumor site to avoid spot heating is managed by controlling the Curie temperature of the magnetic particles. Read More

    Hyperthermia using magnetite cationic liposomes for hamster osteosarcoma.
    Biomagn Res Technol 2004 Mar 25;2(1). Epub 2004 Mar 25.
    Department of Biotechnology, School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
    BACKGROUND: We have developed magnetite cationic liposomes (MCLs) and applied them to local hyperthermia as a mediator. MCLs have a positive charge and generate heat under an alternating magnetic field (AMF) by hysteresis loss. In this study, the effect of hyperthermia using MCLs was examined in an in vivo study of hamster osteosarcoma. Read More

    A biocompatible magnetic film: synthesis and characterization.
    Biomagn Res Technol 2004 Feb 4;2(1). Epub 2004 Feb 4.
    Center for Nanomagnetics and Biotechnology, Florida State University, Tallahassee, Florida 32310, USA.
    BACKGROUND: Biotechnology applications of magnetic gels include biosensors, targeted drug delivery, artificial muscles and magnetic buckles. These gels are produced by incorporating magnetic materials in the polymer composites. METHODS: A biocompatible magnetic gel film has been synthesized using polyvinyl alcohol. Read More

    Biological effects of power frequency magnetic fields: Neurochemical and toxicological changes in developing chick embryos.
    Biomagn Res Technol 2004 Jan 31;2(1). Epub 2004 Jan 31.
    Department of Biochemistry, University College of Science, Osmania University, Hyderabad - 500 007, India.
    BACKGROUND: There are several reports that indicate a linkage between exposure to power frequency (50 - 60 Hz) magnetic fields with abnormalities in the early embryonic development of the chicken. The present study was designed to understand whether power frequency electromagnetic fields could act as an environmental insult and invoke any neurochemical or toxicological changes in developing chick embryo model. METHODS: Fertilized chicken eggs were subjected to continuous exposure to magnetic fields (50 Hz) of varying intensities (5, 50 or 100 microT) for a period of up to 15 days. Read More

    Correlations from gadopentetate dimeglumine-enhanced magnetic resonance imaging after methotrexate chemotherapy for hemorrhagic placenta increta.
    Biomagn Res Technol 2003 Nov 14;1(1). Epub 2003 Nov 14.
    Georgia Reproductive Specialists LLC/Division of Reproductive Endocrinology and Infertility, Department of Obstetrics & Gynecology, Atlanta Medical Center; Atlanta, Georgia, USA.
    OBJECTIVE: To describe pre- and post-methotrexate (MTX) therapy images from pelvic magnetic resonance imaging (MRI) with gadopentetate dimeglumine contrast following chemotherapy for post-partum hemorrhage secondary to placenta increta. MATERIAL AND METHOD: A 28-year-old Caucasian female presented 4 weeks post-partum complaining of intermittent vaginal bleeding. She underwent dilatation and curettage immediately after vaginal delivery for suspected retained placental tissue but 28 d after delivery, the serum beta-hCG persisted at 156 IU/mL. Read More

    Application of magnetic techniques in the field of drug discovery and biomedicine.
    Biomagn Res Technol 2003 Sep 18;1(1). Epub 2003 Sep 18.
    Department of Biochemistry, Faculty of Science, M S University of Baroda, Vadodara, India.
    Magnetic separation technology, using magnetic particles, is quick and easy method for sensitive and reliable capture of specific proteins, genetic material and other biomolecules. The technique offers an advantage in terms of subjecting the analyte to very little mechanical stress compared to other methods. Secondly, these methods are non-laborious, cheap and often highly scalable. Read More

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