- Caitlin S M Cowan,
- Alan E Hoban,
- Ana Paula Ventura-Silva,
- Timothy G Dinan,
- Gerard Clarke,
- John F Cryan
Bioessays 2017 Nov 17. Epub 2017 Nov 17.
Dr. C. S. M. Cowan, Dr. A. P. Ventura-Silva, Prof. T. G. Dinan, Dr. G. Clarke, Prof. J. F. Cryan, APC Microbiome Institute, University College Cork, Cork, Ireland.
The amygdala is a key brain area regulating responses to stress and emotional stimuli, so improving our understanding of how it is regulated could offer novel strategies for treating disturbances in emotion regulation. As we review here, a growing body of evidence indicates that the gut microbiota may contribute to a range of amygdala-dependent brain functions from pain sensitivity to social behavior, emotion regulation, and therefore, psychiatric health. In addition, it appears that the microbiota is necessary for normal development of the amygdala at both the structural and functional levels. Read More