4,260 results match your criteria Biliary Trauma


Long-term results of secondary biliary repair for cholecystectomy-related bile duct injury: results of a tertiary referral center.

Acta Chir Belg 2019 Feb 7:1-10. Epub 2019 Feb 7.

a Department of Abdominal Surgery and Transplantation , Cliniques universitaires Saint-Luc , Brussels , Belgium.

Background: Management of bile duct injury (BDI) after cholecystectomy is challenging. The authors analyzed their center's 49-year experience.

Methods: From 1968 to 2016, 120 consecutive patients were managed in a tertiary HBP center, 105 referred from other centers (Group A), 15 from our center (Group B). Read More

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http://dx.doi.org/10.1080/00015458.2019.1570741DOI Listing
February 2019
1 Read

[Research advances of autoimmune liver diseases in 2018].

Authors:
Y Chen Q X Wang X Ma

Zhonghua Gan Zang Bing Za Zhi 2019 Jan;27(1):14-17

Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine;Institute of Digestive Disease, Shanghai 200001, China.

Autoimmune liver disease is a group of hepatobiliary injuries mediated by abnormal immunity. It mainly includes autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis. Recently, an advancement of diagnostic technology has improved the detection and treatment of autoimmune hepatitis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2019.01.005DOI Listing
January 2019
2 Reads

Laparoscopic subtotal cholecystectomy for Mirizzi syndrome: A report of a case.

Int J Surg Case Rep 2019 Jan 19;55:32-34. Epub 2019 Jan 19.

Department of Surgery, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan. Electronic address:

Introduction: Mirizzi syndrome is a rare complication of gallstone disease. The purpose of this report is to describe the utility of laparoscopic subtotal cholecystectomy for Mirizzi syndrome.

Presentation Of Case: A 53-year-old female presented with dark urine and right upper quadrant pain. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612193002
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http://dx.doi.org/10.1016/j.ijscr.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351350PMC
January 2019
5 Reads

A case of perforation of a pancreatic duct by a pancreatic stent during chemoradiotherapy for pancreatic head cancer: a case report.

Surg Case Rep 2019 Jan 23;5(1):10. Epub 2019 Jan 23.

Department of Surgical Oncology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.

Background: Pancreatic injuries are rare, and no treatment plan has yet been established for grade III injuries. In many cases, pancreatic stent placement has resulted in saving patients. However, some cases of perforation of a pancreatic duct during the placement of a stent have been described, and there are also a few cases of delayed perforation by a pancreatic stent. Read More

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https://surgicalcasereports.springeropen.com/articles/10.118
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http://dx.doi.org/10.1186/s40792-019-0571-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346691PMC
January 2019
11 Reads

Portal vein pseudoaneurysm secondary to pancreatic lymphoma and biliary stent insertion: a rare cause of haemobilia.

CVIR Endovasc 2018 28;1(1). Epub 2018 Jun 28.

2University College London Hospital, Euston Road, London, NW1 2BU UK.

Background: Haemobilia, defined as bleeding from the biliary tree, is a rare entity. The most common cause of haemobilia is iatrogenic trauma, which accounts for 70% of cases. Pseudoaneurysms of the portal vein are an extremely rare cause of haemobilia with only four reported cases to date. Read More

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http://dx.doi.org/10.1186/s42155-018-0011-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319504PMC
June 2018
1 Read

Anticoagulants is a risk factor for spontaneous rupture and hemorrhage of gallbladder: a case report and literature review.

BMC Surg 2019 Jan 5;19(1). Epub 2019 Jan 5.

Department of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.

Background: The spontaneous rupture of the gallbladder is extremely rare, majority of ruptures occur secondary to traumatic injuries. Here, we report a case of spontaneous rupture of the gallbladder with probably cause of oral anticoagulants.

Case Presentation: A 51-year-old woman presented to the emergency room with sudden-onset severe abdominal pain, as well as hypotension and low level of hemoglobin. Read More

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http://dx.doi.org/10.1186/s12893-018-0464-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321697PMC
January 2019
3 Reads

What Have We Learned From Malpractice Claims Involving the Surgical Management of Benign Biliary Disease?: A 128 Million Dollar Question.

Ann Surg 2018 Dec 20. Epub 2018 Dec 20.

Edward P. Lawrence Center for Quality and Safety, Massachusetts General Hospital, Boston, MA.

Objective: We aimed to study the contributing factors and costs of malpractice claims involving the surgical management of benign biliary disease given the emotional, physical, and financial toll of these claims on patients, providers, and the healthcare system.

Summary Background Data: Cholecystectomy complications carry significant morbidity and rank among the leading sources of surgical malpractice claims.

Methods: Using the CRICO Strategies' Comparative Benchmarking System database, representing approximately 30% of all paid and unpaid malpractice claims in the United States, 4081 closed claims filed against general surgeons from 1995 to 2015 were reviewed to isolate 745 cholecystectomy-related claims. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003155DOI Listing
December 2018
1 Read

Mesenchymal chondrosarcoma metastasising to the pancreas.

BMJ Case Rep 2018 Dec 31;11(1). Epub 2018 Dec 31.

General Surgery, Helios Klinikum Berlin-Buch, Berlin, Germany.

The mesenchymal chondrosarcoma (MC) is a rare malignant tumour and accounts for less than 3% of primary chondrosarcomas. Mostly MC arises from the craniofacial bones, the ribs, the ilium, the femur and the vertebrae. A 54-year-old man was treated due to an icterus of unknown origin. Read More

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http://dx.doi.org/10.1136/bcr-2018-226369DOI Listing
December 2018
3 Reads

A duplicated Gallbladder in a Patient Presenting with Acute Cholangitis. A Case Study and a Literature Review.

Ann Hepatol 2018 Dec;18(1):240-245

2nd Dept. of Surgery, "Aretaieio" Hospital, National and Kapodistrian University of Athens, School of Medicine, Greece.

Gallbladder duplication can present a clinical challenge primarily due to difficulties with diagnosis and identification. Recognition of this anomaly and its various types is important since it can complicate a gallbladder disease or a simple hepatobiliary surgical procedure. The case report of a 63-year-old woman who presented with cholangitis and underwent a successful laparoscopic management of symptomatic gallbladder duplication is described, emphasizing several important considerations. Read More

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https://annalsofhepatology.publisherspanel.com/gicid/01.3001
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http://dx.doi.org/10.5604/01.3001.0012.7932DOI Listing
December 2018
12 Reads
2.193 Impact Factor

Endoscopy for treating minor post-cholecystectomy biliary fistula A review of the literature.

Ann Ital Chir 2018 Jun 25;7. Epub 2018 Jun 25.

Aim: Laparoscopic cholecystectomy for gallstone disease is the most common surgical procedures performed in Western countries and bile leaks remain a significant cause of morbidity. A recognized treatment for minor biliary injury is internal biliary decompression by endoscopic retrograde cholangiopancreatography. The aim of this study was to assess the effectiveness of endoscopic strategy in the management of minor biliary injuries. Read More

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June 2018
7 Reads

Rupture of the common bile duct due to blunt trauma, presenting difficulty in diagnosis.

BMJ Case Rep 2018 Dec 10;11(1). Epub 2018 Dec 10.

Surgery, JCHO Chukyo Hospital, Nagoya, Japan.

Rupture of the common bile duct because of blunt trauma is extremely rare. Preoperative diagnosis is very difficult because bile causes little peritoneal irritation. We present a case of a 19-year-old young woman with rupture of the common bile duct due to blunt trauma. Read More

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http://www.bmj.com/lookup/doi/10.1136/bcr-2018-226467
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http://dx.doi.org/10.1136/bcr-2018-226467DOI Listing
December 2018
2 Reads

Clinical outcomes of primary arterial embolization in severe hepatic trauma: A systematic review.

Diagn Interv Imaging 2019 Feb 13;100(2):65-75. Epub 2018 Dec 13.

General, Emergency and Robotic Surgery Unit, San Francesco Hospital, 08100 Nuoro NU, Italy.

Purpose: This purpose of this systematic review was to determine the safety and efficacy of arterial embolization as the primary treatment for grade III-V liver trauma, excluding the postoperative use of arterial embolization.

Material And Methods: A total of 24 studies published between January 2000 and June 2018 qualified for inclusion in this study. Four of them were prospective studies and 20 were retrospective. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22115684183024
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http://dx.doi.org/10.1016/j.diii.2018.10.004DOI Listing
February 2019
5 Reads

Fibroinflammatory Liver Injuries as Preneoplastic Condition in Cholangiopathies.

Int J Mol Sci 2018 Dec 4;19(12). Epub 2018 Dec 4.

School of Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900 Monza, Italy.

The cholangipathies are a class of liver diseases that specifically affects the biliary tree. These pathologies may have different etiologies (genetic, autoimmune, viral, or toxic) but all of them are characterized by a stark inflammatory infiltrate, increasing overtime, accompanied by an excess of periportal fibrosis. The cellular types that mount the regenerative/reparative hepatic response to the damage belong to different lineages, including cholagiocytes, mesenchymal and inflammatory cells, which dynamically interact with each other, exchanging different signals acting in autocrine and paracrine fashion. Read More

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http://www.mdpi.com/1422-0067/19/12/3875
Publisher Site
http://dx.doi.org/10.3390/ijms19123875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321547PMC
December 2018
14 Reads

Surgical management of laparoscopic cholecystectomy (LC) related major bile duct injuries; predictors of short-and long-term outcomes in a tertiary Egyptian center- a retrospective cohort study.

Ann Med Surg (Lond) 2018 Dec 16;36:219-230. Epub 2018 Nov 16.

Radioligy, National Liver Institute, Menoufia University, Shebein Elkoum, Egypt.

Objectives: Laparoscopic cholecystectomy - associated bile duct injury is a clinical problem with bad outcome. The study aimed to analyze the outcome of surgical management of these injuries.

Patients And Methods: We retrospectively analyzed 69 patients underwent surgical management of laparoscopic cholecystectomy related major bile duct injuries in the period from the beginning of 2013 to the beginning of 2018. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251332PMC
December 2018
2 Reads

Laparoscopic Cholecystectomy is Safe Both Day and Night.

J Surg Res 2019 Jan 24;233:163-166. Epub 2018 Aug 24.

Division of Burns, Department of Surgery, Trauma and Critical Care, University of Texas Southwestern Medical Center, Dallas, Texas.

Background: It is reported that performing laparoscopic cholecystectomy (LC) at night leads to increased rates of complications and conversion to open. We hypothesize that it is safe to perform LC at night in appropriately selected patients.

Materials And Methods: We performed a retrospective review of nonelective LC in adults at our institution performed between April 2007 and February 2015. Read More

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http://dx.doi.org/10.1016/j.jss.2018.07.071DOI Listing
January 2019
2 Reads

International publication trends in hepato-pancreato-biliary surgery: emergency compared to oncology.

ANZ J Surg 2018 Dec 4. Epub 2018 Dec 4.

Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Background: There is growing interest in publishing trends given the increasing amount of research publication across various specialities. Studies relating to hepato-pancreato-biliary (HPB) surgery show an oncological focus compared to benign, emergency and trauma.

Methods: Analysis of ISI JCR impact factors in the Web of Knowledge and the Scimago Journal Rank through Scopus was performed to select four readily available, relevant and frequently read journals from the surgery category. Read More

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http://doi.wiley.com/10.1111/ans.14962
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http://dx.doi.org/10.1111/ans.14962DOI Listing
December 2018
6 Reads

[Minimally invasive treatment of biliary tract injury secondary to closed abdominal trauma: Clinical case].

Arch Argent Pediatr 2018 12;116(6):e778-e781

Servicio de Cirugía y Urología Pediátrica, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.

Hepatic and biliary tract injuries due to traumatic causes are rare in pediatric patients. Of the total number of patients with closed abdominal trauma, less than 9 % have liver injury, and the frequency varies between 2 and 3 % of biliary tract lesions. Currently, the recommended treatment for closed abdominal trauma with liver injury without hemodynamic repercussion is conservative. Read More

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http://www.sap.org.ar/docs/publicaciones/archivosarg/2018/v1
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http://dx.doi.org/10.5546/aap.2018.e778DOI Listing
December 2018
1 Read

Etiologies and outcomes of emergency surgery for acute abdominal pain: an audit of 1456 cases in a single center.

Eur J Trauma Emerg Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, Ogaki, Gifu, Japan.

Purpose: There are few studies that have reported the details of emergency surgery for acute abdominal pain. This study aimed to clarify the etiologies and outcomes of emergency abdominal surgery among patients in different age categories.

Methods: Between January 2014 and December 2016, 1456 patients aged 7 years or older who underwent emergency surgery for acute abdominal pain at our institution were enrolled in this study. Read More

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http://link.springer.com/10.1007/s00068-018-1051-3
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http://dx.doi.org/10.1007/s00068-018-1051-3DOI Listing
November 2018
10 Reads

Impact of Machine Perfusion on Biliary Complications after Liver Transplantation.

Int J Mol Sci 2018 Nov 12;19(11). Epub 2018 Nov 12.

Department of Surgery & Transplantation, University Hospital Zurich, 8091 Zurich, Switzerland.

We describe in this review the different types of injuries caused to the biliary tree after liver transplantation. Furthermore, we explain underlying mechanisms and why oxygenated perfusion concepts could not only protect livers, but also repair high-risk grafts to prevent severe biliary complications and graft loss. Accordingly, we summarize experimental studies and clinical applications of machine liver perfusion with a focus on biliary complications after liver transplantation. Read More

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http://www.mdpi.com/1422-0067/19/11/3567
Publisher Site
http://dx.doi.org/10.3390/ijms19113567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274934PMC
November 2018
10 Reads

Transthoracic cholecystectomy following biliary pancreatitis arising from a thoracic herniated gallbladder.

J Visc Surg 2018 Dec 9;155(6):513-515. Epub 2018 Nov 9.

Department of HPB Surgery and Liver Transplant, Beaujon Hospital, Clichy, Université Paris VII Diderot, Assistance Publique-Hôpitaux de Paris, 100, boulevard du Général Leclerc, 92110 Clichy, Paris, France.

Asymptomatic right diaphragmatic rupture with liver and gallbladder herniation and secondary Budd-Chiari syndrome is a rare complication of abdominal trauma. In this setting, the management of gallbladder stones remains poorly described and may require a thoracic approach. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18787886183012
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http://dx.doi.org/10.1016/j.jviscsurg.2018.08.007DOI Listing
December 2018
9 Reads

Hepatic artery pseudoaneurysm, bronchobiliary fistula in a patient with liver trauma.

BMC Surg 2018 Nov 12;18(1):97. Epub 2018 Nov 12.

Department of Surgery, National Academy of Medical Sciences, Kathmandu, Nepal.

Background: Bronchobiliary fistula and hepatic artery pseudoaneurysm are rare complications of hepatic trauma. There are isolated case reports for both pseudoaneurysm and bronchobiliary fistula following hepatic trauma but there aren't reports of both conditions developing in a single patient.

Case Presentation: This case describes an 18 year old hindu male who developed right hepatic artery pseudoaneurysm and bronchobiliary fistula following blunt abdominal trauma. Read More

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https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-01
Publisher Site
http://dx.doi.org/10.1186/s12893-018-0437-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233285PMC
November 2018
17 Reads

Emergency presentations of acute biliary pain: changing patterns of management in a tertiary institute.

ANZ J Surg 2018 Dec 9;88(12):1337-1342. Epub 2018 Nov 9.

HPB and Transplant Unit, Austin Hospital, Melbourne, Victoria, Australia.

Background: Acute biliary pain is the most common presentation of gallstone disease. Untreated patients risk recurrent pain, cholecystitis, obstructive jaundice, pancreatitis and multiple hospital presentations. We examine the outcome of implementing a policy to offer laparoscopic cholecystectomy on index presentation to patients with biliary colic in a tertiary hospital in Australia. Read More

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http://doi.wiley.com/10.1111/ans.14898
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http://dx.doi.org/10.1111/ans.14898DOI Listing
December 2018
18 Reads

In trauma, expect the unexpected: a rare case of post-traumatic pancreatitis associated with salmonellosis and enterocolitis.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Department of Pediatric Surgery, Children's Health Children's Medical Center Dallas, Dallas, Texas, USA.

A 16-year-old Hispanic man was transferred to our level I paediatric trauma centre with pancreatitis. Ten days prior, he had sustained a gunshot wound to the abdomen requiring an exploratory laparotomy for repair of a traumatic left diaphragmatic injury. Additional injuries included gastric, renal, liver and pancreatic lacerations as well as a T12 burst fracture that resulted in paraplegia. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22628
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http://dx.doi.org/10.1136/bcr-2018-226286DOI Listing
November 2018
4 Reads

Management of Segmental Bile Duct Injuries After Cholecystectomy: a Systematic Review.

J Gastrointest Surg 2018 Nov 6. Epub 2018 Nov 6.

1st Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Background: Injuries to segmental or aberrant bile ducts are encountered less commonly than their major bile duct counterparts and present a unique diagnostic and therapeutic challenge, since the nature of this injury involves a transected bile duct that loses its communication with the main ductal system. In this systematic review, we aim to pool available data on this particular type of biliary injury in an effort to outline available diagnostic and therapeutic modalities and evaluate their efficacy.

Materials And Methods: An extensive literature search was performed on MEDLINE, Scopus, and Web of Science to identify isolated segmental or aberrant bile duct injuries. Read More

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http://dx.doi.org/10.1007/s11605-018-4027-zDOI Listing
November 2018
1 Read

Biliary Complications During and After Donor Hepatectomy in Living Donor Liver Transplantation Focusing on Characteristics of Biliary Leakage and Treatment for Intraoperative Bile Duct Injury.

Transplant Proc 2018 Nov 15;50(9):2705-2710. Epub 2018 Mar 15.

Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan.

Background: Biliary complication is one of the major donor complications during and after hepatectomy in living donor liver transplantation (LDLT). We evaluated risk factors for donor biliary complication in adult-to-adult LDLT.

Patients And Methods: From March 2002 to November 2016, 126 consecutive patients who underwent donor hepatectomy in adult-to-adult LDLT were divided into 2 groups according to biliary compilations: nonbiliary complication (non-BC) group (n = 114) and biliary complication (BC) group (n = 12). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183037
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http://dx.doi.org/10.1016/j.transproceed.2018.03.045DOI Listing
November 2018
5 Reads

A comparison of cholecystitis grading scales.

J Trauma Acute Care Surg 2018 Nov 5. Epub 2018 Nov 5.

UT Southwestern Division of General and Acute Care Surgery.

Background: Previously, our group developed the Parkland Grading Scale for Cholecystitis (PGS) to stratify gallbladder (GB) disease severity that can be determined immediately when performing laparoscopic cholecystectomy (LC). In prior studies, PGS demonstrated excellent interrater reliability and was internally validated as an accurate measure of LC outcomes. Here, we compare PGS against a more complex cholecystitis severity score developed by the national trauma society (AAST), which requires clinical, operative, imaging, and pathologic inputs, as a predictor of LC outcomes. Read More

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http://dx.doi.org/10.1097/TA.0000000000002125DOI Listing
November 2018
4 Reads

Management of post cholecystectomy vascular injuries.

Surgeon 2018 Nov 2. Epub 2018 Nov 2.

Department of Surgical Gastroenterology, King George's Medical University, Lucknow, 226003, Uttar Pradesh, India. Electronic address:

Introduction: Vasculobiliary and vascular injuries following cholecystectomy are the most serious complications requiring complex surgical management resulting in greater patient morbidity and mortality.

Methodology: The study was performed at a tertiary teaching hospital of North India. Records of patients referred for biliary or vascular injury sustained during cholecystectomy were reviewed retrospectively to identify patients with vascular injury between January 2009 and March 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1479666X183012
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http://dx.doi.org/10.1016/j.surge.2018.10.002DOI Listing
November 2018
12 Reads
2.207 Impact Factor

Magnesium isoglycyrrhizinate alleviates liver injury in obese rats with acute necrotizing pancreatitis.

Pathol Res Pract 2019 Jan 28;215(1):106-114. Epub 2018 Oct 28.

Dept of General Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China. Electronic address:

Objective: For patients with acute necrotizing pancreatitis (ANP), a high body mass index (BMI) increases the likelihood of acute hepatic injury (AHI). In the current study, we explored whether magnesium isoglycyrrhizinate (MgIg) could alleviate ANP-induced liver injury in obese rats.

Methods: Sprague-Dawley (SD) rats were selected for the present study, and the ANP model was established by retrograde injection of 5% sodium taurocholate into the biliary-pancreatic duct. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03440338183093
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http://dx.doi.org/10.1016/j.prp.2018.10.030DOI Listing
January 2019
11 Reads

Indications and outcomes of duodenum-preserving resection of the pancreatic head in children.

Pediatr Surg Int 2018 Nov 1. Epub 2018 Nov 1.

Department of Surgery, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Aim Of Study: Duodenum-preserving resection of the pancreatic head (DPRPH) with Roux-en-Y pancreatojejunostomy is a procedure used to remove focal pathological lesions of the pancreatic head. Although predominantly used in adult patients, it is both safe and effective in children. The aim of this study was to review our experience with this procedure, with focus on its indications, complications and long-term outcomes. Read More

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http://link.springer.com/10.1007/s00383-018-4410-6
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http://dx.doi.org/10.1007/s00383-018-4410-6DOI Listing
November 2018
10 Reads

Efficacy of Endobiliary Radiofrequency Ablation using a Novel Endoluminal Radiofrequency Ablation Catheter in a Swine Model.

J Invest Surg 2018 Oct 31:1-7. Epub 2018 Oct 31.

c Laboratory Animal Research Center , Korea University College of Medicine , Seoul , Republic of Korea.

Purpose: Endobiliary radiofrequency ablation (RFA) is a new endoscopic ablative technique. However, the ideal power setting for RFA has not yet been clarified. Therefore, we intended to evaluate the effects of endobiliary RFA according to time variations using novel RFA. Read More

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http://dx.doi.org/10.1080/08941939.2018.1489566DOI Listing
October 2018
12 Reads

Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases.

J Biomed Sci 2018 Oct 26;25(1):75. Epub 2018 Oct 26.

Departments of Pediatrics, National Taiwan University College of Medicine and Children's Hospital, 17F, No. 8, Chung Shan S. Rd, Taipei, 100, Taiwan.

Background: Jaundice is a common symptom of inherited or acquired liver diseases or a manifestation of diseases involving red blood cell metabolism. Recent progress has elucidated the molecular mechanisms of bile metabolism, hepatocellular transport, bile ductular development, intestinal bile salt reabsorption, and the regulation of bile acids homeostasis.

Main Body: The major genetic diseases causing jaundice involve disturbances of bile flow. Read More

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https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929
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http://dx.doi.org/10.1186/s12929-018-0475-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203212PMC
October 2018
16 Reads

Dual-Incision Laparoscopic Spleen-Preserving Distal Pancreatectomy: Merits Compared to the Conventional Method.

J Gastrointest Surg 2018 Oct 26. Epub 2018 Oct 26.

Department of Hepato-biliary and Pancreas Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Background: Herein, we assess the safety and feasibility of dual-incision laparoscopic spleen-preserving distal pancreatectomy (DILSPDP) through lateral approach with reduced trocars for benign and low-grade malignancy in pancreas tail. We compare DILSPDP with surgical outcomes of conventional laparoscopic spleen-preserving distal pancreatectomy (LSPDP).

Methods: Patients with benign pancreas tail mass that had been scheduled for LSPDP were selected to undergo DILSPDP. Read More

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http://link.springer.com/10.1007/s11605-018-4013-5
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http://dx.doi.org/10.1007/s11605-018-4013-5DOI Listing
October 2018
5 Reads

Role of TGR5 (GPBAR1) in Liver Disease.

Semin Liver Dis 2018 Nov 24;38(4):333-339. Epub 2018 Oct 24.

Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty at Heinrich-Heine-University, Düsseldorf, Germany.

TGR5 (GPBAR1) is a G protein-coupled receptor activated by primary and secondary bile acids, which is expressed in different nonparenchymal cells of the liver, such as sinusoidal endothelial cells, Kupffer cells, cholangiocytes as well as activated hepatic stellate cells. In liver, TGR5 modulates microcirculation, inflammation, regeneration, biliary secretion and proliferation as well as gallbladder filling. Absence of TGR5 renders mice more susceptible toward infectious, inflammatory, metabolic as well as cholestatic liver injuries. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669940
Publisher Site
http://dx.doi.org/10.1055/s-0038-1669940DOI Listing
November 2018
12 Reads

Maintenance of the fistulous tract after recanalization via magnetic compression anastomosis in completely obstructed benign biliary stricture.

Scand J Gastroenterol 2018 Oct - Nov;53(10-11):1393-1398. Epub 2018 Oct 23.

a Department of Internal Medicine , Severance Hospital, Yonsei University College of Medicine , Seoul , Korea.

Objective: This study compared the efficacy of a percutaneous transhepatic cholangioscopy (PTCS) catheter and a fully covered self-expandable metal stent (FCSEMS) for maintaining biliary tract patency after magnetic compression anastomosis (MCA).

Methods: This study included patients with completely obstructed benign biliary stricture (BBS), which was resolved by MCA and subsequent insertion of a PTCS catheter or FCSEMS. We compared the restenosis-free time after removal of the PTCS catheter or FCSEMS, and the rate of complications. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1
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http://dx.doi.org/10.1080/00365521.2018.1526968DOI Listing
October 2018
10 Reads

A-kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide-induced liver injury.

Oncol Lett 2018 Nov 4;16(5):5907-5915. Epub 2018 Sep 4.

College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

AKAP12 belongs to A-kinase anchoring protein (AKAP) family of scaffold proteins and is known as a tumor suppressor in several human cancer types. Its role as a tumor suppressor in hepatocellular carcinoma (HCC) was proposed due to its downregulation and epigenetic modification in human HCC; however, the effect of its deficiency on liver injuries, such as liver fibrosis and cancer has been poorly studied. By analyzing tumor and non-tumor tissues of 15 patients with HCC, it was confirmed that AKAP12 expression was downregulated in human HCC as compared with adjacent non-tumor tissues. Read More

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http://www.spandidos-publications.com/10.3892/ol.2018.9396
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http://dx.doi.org/10.3892/ol.2018.9396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176350PMC
November 2018
11 Reads

Primary biliary cholangitis and bone disease.

Best Pract Res Clin Gastroenterol 2018 Jun - Aug;34-35:63-70. Epub 2018 Jun 14.

Department of Rheumatology, Metabolic Bone Diseases Unit, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.

Osteoporosis, characterized by compromised bone strength leading to fragility fractures, is a common event in patients with primary biliary cholangitis (PBC). Osteomalacia, defined by poor bone mineralization is very uncommon. The pathogenesis of osteoporosis is not well clarified, but it mainly results from low bone formation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15216918183000
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http://dx.doi.org/10.1016/j.bpg.2018.06.005DOI Listing
December 2018
11 Reads
3.480 Impact Factor

A retrospective study of 157 hospitalized cats with pancreatitis in a tertiary care center: Clinical, imaging and laboratory findings, potential prognostic markers and outcome.

J Vet Intern Med 2018 Nov 13;32(6):1874-1885. Epub 2018 Oct 13.

Department of Small Animal Internal Medicine, Koret School of Veterinary Medicine - Veterinary Teaching Hospital and Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Background: Pancreatitis in cats (FP) has been increasingly diagnosed in recent years, but clinical studies of large numbers of affected cats are scarce.

Objectives: To describe a large cohort of cats with FP requiring hospitalization.

Animals: One hundred and fifty-seven client-owned cats. Read More

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http://doi.wiley.com/10.1111/jvim.15317
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http://dx.doi.org/10.1111/jvim.15317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271303PMC
November 2018
8 Reads

Focal change of the pancreatic texture using a direct injection mixture of N-butyl cyanoacrylate and lipiodol in the pig model: a strategy for preventing pancreatic leakage during pancreatic surgery.

Ann Surg Treat Res 2018 Oct 28;95(4):175-182. Epub 2018 Sep 28.

Department of Hepato-Biliary and Pancreas Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Purpose: A soft texture of the pancreas is one of the most important predisposing factors for a pancreatic fistula. Thus, in a porcine model, we investigated a method to harden the pancreas locally by directly injecting an artificial material.

Methods: During the laparotomy, 51 samples from 17 pigs, including 13 survival models, were randomly divided into 3 groups and either received a direct injection into the pancreas of MHL (1:4 mixture of histoacryl [n-butyl cyanoacrylate] and lipiodol) (group E) or saline (group C) or only received a pinprick into the pancreas without injecting a substance (sham). Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4174/astr.2018.9
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http://dx.doi.org/10.4174/astr.2018.95.4.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172351PMC
October 2018
2 Reads

Complications of percutaneous liver biopsy in living donor liver transplantation: Two case reports.

Medicine (Baltimore) 2018 Oct;97(40):e12742

Chang Gung University, College of Medicine, Taiwan.

Rationale: According to previously published studies, major complications arising from a percutaneous liver biopsy are rare and occur in less than 0.1% of cases. This report describes an approach to percutaneous liver biopsy that can help avoid damage to the liver in a living donor liver transplantation (LDLT) setting. Read More

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http://dx.doi.org/10.1097/MD.0000000000012742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200465PMC
October 2018
4 Reads

An analysis of the iatrogenic biliary injury after robotic cholecystectomy. Current data and future considerations.

Eur Rev Med Pharmacol Sci 2018 Sep;22(18):6072-6076

Health Center Alexandras, Athens, Greece.

Objective: Minimally invasive techniques are the gold standard in surgery. Since conventional laparoscopic approach has been widely adopted, surgeons in their effort to further improve their skills passed to the era of the robotic assistance. The widespread adoption of robotics has led to the inevitable usage of robotic technology both in simple, as well as in more complicated procedures. Read More

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http://dx.doi.org/10.26355/eurrev_201809_15945DOI Listing
September 2018

Detection and characterization of traumatic bile leaks using Gd-EOB-DTPA enhanced magnetic resonance cholangiography.

Sci Rep 2018 Oct 2;8(1):14612. Epub 2018 Oct 2.

Division of Trauma and Emergency Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan City, Taiwan.

Expanding bile leaks after blunt liver trauma require more aggressive treatment than contained bile leaks. In this retrospective study approved by institution review board, we analyzed if non-invasive contrast-enhanced magnetic resonance cholangiography (CEMRC) using hepatocyte-specific contrast agent (gadoxetic acid disodium) could detect and characterize traumatic bile leaks. Between March 2012 and December 2014, written informed consents from 22 included patients (17 men, 5 women) with a median age of 24. Read More

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http://www.nature.com/articles/s41598-018-32976-0
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http://dx.doi.org/10.1038/s41598-018-32976-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168538PMC
October 2018
2 Reads
5.080 Impact Factor

Perioperative and Long-Term Outcomes of Laparoscopic Versus Open Lymphadenectomy for Biliary Tumors: A Propensity-Score-Based, Case-Matched Analysis.

Ann Surg Oncol 2019 Feb 1;26(2):564-575. Epub 2018 Oct 1.

Hepatobiliary Surgery Division, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132, Milan, Italy.

Background: The purpose of this study was to compare patients undergoing MILS and open liver resections with associated lymphadenectomy for biliary tumors (intrahepatic cholangiocarcinoma and gallbladder cancer) in a case-matched analysis using propensity scores.

Methods: A total of 104 consecutive patients underwent liver resection with associated locoregional lymphadenectomy by laparoscopic approach constituted the study group (MILS group). The MILS group was matched in a ratio of 1:2 with patients who had undergone open resection for primary biliary cancers (Open group). Read More

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http://dx.doi.org/10.1245/s10434-018-6811-0DOI Listing
February 2019
12 Reads

The Change in Surgical Case Diversity Over the Past 15 Years and the Influence on the Pursuit of Surgical Fellowship.

Am Surg 2018 Sep;84(9):1476-1479

The surgical community has expressed concern that residents do not receive the same caliber training as their predecessors and the increase in fellowships have been described as secondary to perceived lack of preparation. Yet, data show no change in total cases even after implementation of the 80-hour workweek. It is hypothesized that the increasing subspecialization of general surgery may decrease in certain resident case numbers. Read More

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September 2018
3 Reads

The Pucker sign: an operative and radiological indicator of impending operative difficulty due to severe chronic contractive inflammation in cholecystectomy.

J Hepatobiliary Pancreat Sci 2018 Oct 22;25(10):455-459. Epub 2018 Oct 22.

Section of Hepato-Pancreato-Biliary Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine in St. Louis, 660 S. Euclid Avenue, CB 8109, St. Louis, MO, 63110, USA.

Introduction: Marked inflammatory contraction of the gallbladder at the time of cholecystectomy is associated with biliary injury.

Methods: The evolution of contraction is traced in two patients who developed acute cholecystitis.

Results: Within months the gallbladder became fibrotically contacted and in doing so pulled the adjacent liver down, puckering the surface of the liver. Read More

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http://dx.doi.org/10.1002/jhbp.583DOI Listing
October 2018
6 Reads

Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases.

Int J Mol Sci 2018 Sep 25;19(10). Epub 2018 Sep 25.

Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Via Borelli 50, 00161 Rome, Italy.

Two distinct stem/progenitor cell populations of biliary origin have been identified in the adult liver and biliary tree. Hepatic Stem/progenitor Cells (HpSCs) are bipotent progenitor cells located within the canals of Hering and can be differentiated into mature hepatocytes and cholangiocytes; Biliary Tree Stem/progenitor Cells (BTSCs) are multipotent stem cells located within the peribiliary glands of large intrahepatic and extrahepatic bile ducts and able to differentiate into hepatic and pancreatic lineages. HpSCs and BTSCs are endowed in a specialized niche constituted by supporting cells and extracellular matrix compounds. Read More

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http://dx.doi.org/10.3390/ijms19102917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213374PMC
September 2018
5 Reads

Laparoscopic cholecystectomy complications: a new case report of a right hepatic artery pseudoaneurysm that caused jaundice.

Rev Esp Enferm Dig 2018 Dec;110(12):832

Gastroenterología, HospitalItaliano de Buenos Aires, Argentina.

Iatrogenic vascular injuries of the hepatic artery are infrequent and a serious complication of LC. There is no doubt about the many advantages of LC when compared to open cholecystectomy. Despite this, there is an increase in the reported incidence (0. Read More

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http://dx.doi.org/10.17235/reed.2018.5668/2018DOI Listing
December 2018
3 Reads

Secondary sclerosing cholangitis following extracorporeal membrane oxygenation for acute respiratory distress in polytrauma.

Clin Case Rep 2018 Sep 2;6(9):1849-1853. Epub 2018 Aug 2.

Wythenshawe Hospital Manchester University Hospitals NHS Foundation Trust Manchester UK.

Secondary sclerosing cholangitis is a recently identified phenomenon affecting the biliary tree. A subtype has been described in critically ill patients (SSC-CIP). However, underlying mechanisms are unknown, and few cases have been reported following extracorporeal membrane oxygenation (ECMO). Read More

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http://dx.doi.org/10.1002/ccr3.1660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132136PMC
September 2018
2 Reads

Management of liver hydatid cyst with cystobiliary communication and acute cholangitis: a 27-year experience.

Eur J Trauma Emerg Surg 2018 Sep 6. Epub 2018 Sep 6.

Department of Radiology, Fattouma Bourguiba Hospital, Monastir, Tunisia.

Purpose: The rupture of the hydatid cyst into the bile ducts is a common and serious complication. The rupture can be latent or revealed after a complication such as acute cholangitis. The objective of this study was to discuss the clinical features, radiographic findings, and surgical treatment of this rare complication. Read More

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http://dx.doi.org/10.1007/s00068-018-0995-7DOI Listing
September 2018
10 Reads
0.380 Impact Factor

Paediatric duodenal injury complicated by common bile duct rupture due to blunt trauma: a multispecialist approach.

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

Department of Paediatric Surgery, St George's Hospital, London, UK.

We report a case of late presenting duodenal perforation with common bile duct rupture secondary to blunt handlebar trauma in an 11-year-old boy. The patient presented with upper abdominal wall ecchymosis, pain and vomiting. He was discharged after 24 hours with resolving symptoms. Read More

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http://dx.doi.org/10.1136/bcr-2018-225221DOI Listing
August 2018
3 Reads

Management of Biliary Stricture Following Emergent Pancreaticoduodenectomy for Trauma: Report of Two Cases.

Cureus 2018 Jun 18;10(6):e2829. Epub 2018 Jun 18.

Trauma Surgery, Creighton University School of Medicine, Phoenix, USA.

Stricturing of the biliary-enteric anastomosis is a known complication of emergent pancreaticoduodenectomy (PD) performed for trauma. Percutaneous techniques have become the first-line option for the management of these strictures. In cases where percutaneous intervention fails, surgical revision of the biliary enteric anastomosis is necessary. Read More

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http://dx.doi.org/10.7759/cureus.2829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101440PMC
June 2018
19 Reads