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Endoscopy 2022 Jun 24. Epub 2022 Jun 24.

Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.

Rev Esp Enferm Dig 2022 Jun 24. Epub 2022 Jun 24.

Sección de Aparato Digestivo, Hospital General Universitario Reina Sofía, España.

Neuroendocrine tumors (NETs) or carcinoids represent a small percentage of gastrointestinal neoplasms (2%). The ileum (41.8%), rectum (27. Read More

Minim Invasive Ther Allied Technol 2022 Jun 22:1-6. Epub 2022 Jun 22.

Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.

Introduction: Stent or endoscopic nasobiliary drainage (ENBD) catheter placement for a tight, complicated biliary stricture is still technically challenging. A thin, 4-Fr ENBD catheter (4-Fr catheter) has been developed to overcome this difficulty. The study aimed to evaluate the feasibility of the 4-Fr catheter for endoscopic biliary drainage (EBD). Read More

Radiol Case Rep 2022 Aug 11;17(8):2874-2877. Epub 2022 Jun 11.

St. Joseph's University Medical Center, Department of Gastroenterology, 703 Main Street, Paterson, NJ 07503 USA.

Intraductal papillary mucinous neoplasms (IPMN) are mucin producing tumors which arise from epithelial cells of the main pancreatic duct, pancreatic branch ducts, or both. They are characterized by mucin-producing columnar cells, papillary ductal proliferation, cyst formation, and varying degrees of dysplasia. IPMNs are classified as main duct or branch duct based upon the pancreatic duct anatomy which the IPMN is arising from. Read More

World J Hepatol 2022 May;14(5):992-1005

Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.

Background: Studies have shown that covered self-expandable metallic stents (CSEMS) with a low axial forces after placement can cause early recurrent biliary obstruction (RBO) due to precipitating sludge formation.

Aim: To ascertain whether the angle of CSEMS after placement is a risk factor for RBO in unresectable distal malignant biliary obstruction (MBO).

Methods: Between January 2010 and March 2019, 261 consecutive patients underwent self-expandable metallic stent insertion by endoscopic retrograde cholangiopancreatography at our facility, and 87 patients were included in this study. Read More

World J Hepatol 2022 May;14(5):1038-1046

Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague 14021, Czech Republic.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) is a method used to decrease portal hypertension. Biliary stricture is the rarest of the complications associated with this procedure with only 12 cases previously reported in the literature. None of these cases have documented the resolution of biliary stenosis induced by a stent graft. Read More

Acta Gastroenterol Belg 2022 Apr-Jun;85(2):403-405

Department of Gastroenterology, Catholic University of Louvain (UCLouvain), CHU UCL Namur, Yvoir, Belgium.

Carbohydrate antigen 19-9 (CA 19-9) is a biological marker used to diagnose and monitor the progression of various cancers. Elevated CA 19-9 has also been sporadically observed in Helicobacter pylori infected patients. Similar to H. Read More

Acta Gastroenterol Belg 2022 Apr-Jun;85(2):393-395

Düzce University, Faculty of Medicine, Department of Gastroenterology, Düzce, Turkey.

Background: Complete esophageal obstruction (CEO) is a rare condition of which treatment options are challenging. Surgery is the main treatment with high morbidity and mortality rates. Magnetic compression anastomosis (MCA) is a novel technique developed to restore lumen patency in gastrointestinal and biliary tracts. Read More

Wideochir Inne Tech Maloinwazyjne 2022 Jun 9;17(2):279-288. Epub 2022 Jan 9.

Department of Interventional Therapy, Affiliated Hospital of Gansu Medical College, Pingliang, China.

Introduction: Both side-by-side (SBS) and stent-in-stent (SIS) bilateral stenting have been used for patients with malignant hilar biliary obstruction (MHBO). However, it is unclear which technique is better.

Aim: This meta-analysis is conducted to investigate the clinical efficacy and safety of SBS and SIS bilateral stenting for patients with MHBO. Read More

Rev Esp Enferm Dig 2022 Jun 15. Epub 2022 Jun 15.

Gastroenterology , Centro Hospitalar Universitário de São João, Portugal.

A 77-year-old female with previous medical history of non-cirrhotic chronic hepatitis B and hepatocellular carcinoma treated with sequential partial hepatectomy followed by transarterial chemoembolization complained of pruritus and jaundice. Magnetic resonance cholangiopancreatography revealed a peri-hilar ill-defined stenosing lesion suggestive of malignancy. Endoscopic retrograde cholangiopancreatography with cholangioscopy confirmed a circumferential peri-hilar stenosis with fragile mucosa and tortuous dilated vessels and biopsies of this area were consistent cholangiocarcinoma. Read More

Surg Case Rep 2022 Jun 14;8(1):111. Epub 2022 Jun 14.

Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Gunma University, 3-39-22, Showa-machi, Maebashi, Gunma, Japan.

Background: Although visceral aneurysms are relatively rare, it can be life-threatening in case it ruptures. We report a case of Mirizzi syndrome accompanied by a pseudoaneurysm that ruptured into the gallbladder.

Case Presentation: The patient was a 73-year-old woman with persistent gastrointestinal bleeding and progressive jaundice. Read More

Endosc Int Open 2022 Jun 10;10(6):E917-E918. Epub 2022 Jun 10.

Department of Gastroenterology, Aichi Medical University, Aichi, Japan.

Gastrointest Endosc Clin N Am 2022 Jul 11;32(3):507-525. Epub 2022 May 11.

Division of Endosonography, Institute of Digestive and Liver Care, SL Raheja Hospital-A Fortis Associate, Mumbai 400016, India.

Endoscopic ultrasound (EUS)-guided biliary interventions have evolved to become an integral part of advanced gastrointestinal endoscopy units. EUS-guided biliary drainage is an accepted alternative for patients with failed ERCP or altered surgical anatomy. The potential advantages of EUS-guided interventions include choice of biliary access from stomach or duodenum, choice of stent exit in stomach and duodenum, and possibility of avoiding traversing through the obstruction. Read More

Gastrointest Endosc Clin N Am 2022 Jul 11;32(3):427-453. Epub 2022 May 11.

Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indiana University Health-University Hospital, 550 North University Boulevard, Suite 1634, Indianapolis, IN 46202, USA.

Malignant hilar biliary obstruction (MHO), an aggressive perihilar biliary obstruction caused by cholangiocarcinoma, gallbladder cancer, or other metastatic malignancies, has a poor prognosis. Surgical resection is the only curative treatment method for biliary malignancies. However, most of the patients with MHO cannot undergo surgeries on presentation because of an advanced inoperable state or a poor performance state due to old age or comorbid diseases. Read More

J Clin Med 2022 May 30;11(11). Epub 2022 May 30.

Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.

Self-expandable metallic stents (SEMSs) are typically inserted in patients with unresectable malignant biliary obstruction. However, SEMSs are susceptible to occlusion. To overcome this issue, we developed a large-bore, dumbbell-shaped, fully covered SEMS (FCSEMS-L) and compared its efficacy and safety with those of a conventional FCSEMS (FCSEMS-C) in patients with malignant biliary obstruction. Read More

Surg Endosc 2022 Jun 9. Epub 2022 Jun 9.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil Songpa-gu, Seoul, 05505, South Korea.

Background And Aims: Endoscopic ultrasound (EUS)-guided hepaticogastrostomy (HGS) may be a feasible and useful alternative in patients with malignant biliary obstruction (MBO) after failed endoscopic retrograde cholangiopancreatography (ERCP). To date, the risk factors for adverse events (AEs) and long-term outcomes of EUS-HGS have not been fully explored according to stent type. Therefore, we evaluated potential risk factors for AEs and long-term outcomes of EUS-HGS. Read More

Dig Liver Dis 2022 Jun 7. Epub 2022 Jun 7.

Division of Gastroenterology, Paoli-Calmettes Institute, Marseille, France.

Background: EUS-guided hepaticogastrostomy (EUS-HGS) is a recognized second-line strategy for biliary drainage when endoscopic retrograde cholangiopancreatography fails or is impossible. Substantial technical and procedural progress in performing EUS-HGS has been achieved. The present study wanted to analyze whether growing experience in current practice has changed patient outcomes over time. Read More

J Clin Exp Hepatol 2022 May-Jun;12(3):755-766. Epub 2021 Dec 20.

Department of General, Visceral and Vascular Surgery, Experimental Transplantation Surgery, University Hospital Jena, Drackendorfer Strasse 1, 07747, Jena, Germany.

Background: Obstructive cholestasis can lead to significant alterations of the biliary tree depending on the extent and duration of the biliary occlusion. Current experimental studies reported about advanced techniques for corrosion cast and 3D reconstruction (3D-reco) visualizing delicate microvascular structures in animals. We compared these two different techniques for visualization and quantitative assessment of the obstructed murine biliary tree with classical 2D histology. Read More

Intern Med 2022 Jun 7. Epub 2022 Jun 7.

First Department of Internal Medicine, Gifu University Hospital, Japan.

A 76-year-old woman with advanced pancreatic cancer developed recurrent cholecystitis after covered self-expandable metal stent (CSEMS) placement. The cholecystitis was refractory to repeated percutaneous transhepatic gallbladder drainage (PTGBD). Cholecystography showed a patent cystic duct with right and cranial side bifurcation, which is indicative of an increased likelihood of success of endoscopic transpapillary gallbladder drainage (ETGBD). Read More

Gastrointest Endosc 2022 Jun 3. Epub 2022 Jun 3.

Klinikum Nürnberg, Department of Gastroenterology, Nürnberg, Germany.

Background And Aims: Endobiliary radiofrequency ablation (RFA), usually combined with endoscopic stent insertion, is a simple procedure with the potential to improve stent patency and patient survival in case of malignant biliary obstruction. We conducted this randomized multicenter trial to evaluate the impact of RFA on stent patency.

Methods: 86 patients with malignant biliary obstruction and nonresectable tumors (pancreatic carcinoma, cholangiocarcinoma, or metastases) were included. Read More

Medicine (Baltimore) 2022 Jun 3;101(22):e29408. Epub 2022 Jun 3.

Clinical Study Support Center, Wakayama Medical University, Wakayama, Japan.

Introduction: Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is a novel drainage option for patients with an inaccessible papilla. Although EUS-HGS has clinical benefits in patients for whom endoscopic retrograde cholangiopancreatography (ERCP) has failed, the rates of adverse events (AEs) associated with EUS-HGS, such as bile peritonitis and stent migration, are higher than for other procedures. The development of a dedicated system for EUS-HGS is therefore desirable to reduce the rate of AEs. Read More

World J Gastrointest Surg 2022 Apr;14(4):341-351

Emergency Department/Intensive Care Unit, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.

Background: Despite being a benign disease, hepatolithiasis has a poor prognosis because of its intractable nature and frequent recurrence. Nonsurgical treatment is associated with high incidences of residual and recurrent stones. Consequently, surgery hepatic lobectomy or segmental hepatectomy has become the main treatment modality. Read More

Prz Gastroenterol 2022 14;17(2):116-122. Epub 2021 Jul 14.

Department of Radiology, Xuzhou Central Hospital, Xuzhou, China.

Introduction: Between 42% and 77% of patients with distal malignant biliary obstruction (MBO) suffer from pancreatic carcinoma (PC).

Aim: To analyse the clinical efficacy of stenting accompanied by high-intensity focused ultrasound (HIFU) ablation in patients with distal MBO from PC.

Material And Methods: Relevant articles published through March 2021 were identified in the Pubmed, Cochrane Library, Embase, Wanfang, VIP, and CNKI databases. Read More

BMC Infect Dis 2022 Jun 4;22(1):518. Epub 2022 Jun 4.

Department of Clinical Laboratory Medicine, Shizuoka General Hospital, Kitaandou 4-27-1, Aoi-ku, Shizuoka, Japan.

Backgrounds: Actinomyces species are gram-positive, obligate anaerobic rods and are rare causes of cholecystitis. Because Actinomyces species are anaerobic bacteria, it is difficult for Actinomyces to survive in bile apart from A. naeslundii. Read More

Int J Surg Case Rep 2022 May 22;94:107113. Epub 2022 Apr 22.

Department of General Surgery, Mohamed VI University Hospital, Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery Experimental and Medical Simulation, Oujda, Morocco.

Biliary ileus is a consequence of the migration of a gallstone from the gallbladder to the digestive tract, most often via a biliodigestive fistula that causes a bowel obstruction. The clinic is atypical and capricious, including bowel obstruction and signs of cholecystitis, causing a delay in diagnosis. The therapeutic objective is to remove the intestinal obstacle by an enterotomy with stone extraction, with or without treatment of the biliary pathology (cholecystectomy and biliary fistula cure). Read More

Arch Pathol Lab Med 2022 Jun 3. Epub 2022 Jun 3.

Liver Center and Gastrointestinal Division (Wilechansky, Chung) at the Massachusetts General Hospital, Boston, Massachusetts.

Context.–: Coronavirus disease 2019 (COVID-19) has been associated with liver injury, and a small subset of patients recovering from severe disease have shown persistent markedly elevated liver biochemistries for months after infection.

Objective. Read More