161,214 results match your criteria Best Practice & Research: Clinical Rheumatology[Journal]


Improved dialysis removal of protein-bound uremic toxins by salvianolic acids.

Phytomedicine 2018 Dec 16;57:166-173. Epub 2018 Dec 16.

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

Background: Indoxyl sulfate (IS) and p-cresyl sulfate (pCS) are two key protein-bound uremic toxins that accumulate in patients with end-stage renal disease. IS and pCS cannot be efficiently removed by conventional hemodialysis because they are highly bound to proteins. One promising means to optimize the removal of protein-bound uremic toxins involves using binding competitors to liberate uremic toxins from protein-binding partners. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.12.018DOI Listing
December 2018

Mucoepidermoid carcinoma of the head and neck in children.

Int J Pediatr Otorhinolaryngol 2019 Feb 10;120:93-99. Epub 2019 Feb 10.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02115, United States. Electronic address:

Introduction: Mucoepidermoid carcinoma is a rare malignant salivary gland neoplasm in the pediatric population. Few studies have discussed best practice with respect to diagnosis and treatment in children.

Objective: To present our institution's experience with the evaluation and management of pediatric mucoepidermoid carcinoma of the head and neck. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.020DOI Listing
February 2019

Red blood cell transfusion and its alternatives in oncologic surgery-A critical evaluation.

Crit Rev Oncol Hematol 2019 Feb 6;134:1-9. Epub 2018 Dec 6.

Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe-University Frankfurt/Main, Theodor-Stern-Kai 7, 60590, Frankfurt/Main, Germany. Electronic address:

Although blood transfusions have been used for more than 100 years and their potential to save lives is indisputable, there is still limited data on medium- and long-term outcomes after hemotherapy. Until recently, red blood cell transfusions represented the most commonly employed treatment for cancer anemia. As transfusions have been related to worse patient outcome in oncologic surgery, preventive strategies and alternative treatment approaches in the perioperative setting are warranted. Read More

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http://dx.doi.org/10.1016/j.critrevonc.2018.11.011DOI Listing
February 2019

Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.

Clin Microbiol Infect 2019 Feb 13. Epub 2019 Feb 13.

Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital of Basel and University of Basel, Basel, Switzerland.

Background: Adjunctive systemic antibiotic therapy for treatment of bacterial endophthalmitis is controversial but common practice due to the severity of the disease. In absence of guidance documents, several antibiotic regimens are being used without applying evidence-based prescribing, thus leading to inappropriate treatment of this serious eye condition.

Objectives: To summarize available data on intravitreal penetration of systemically administered antibiotics and to discuss their usefulness from a microbiological and pharmacological point of view. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.01.017DOI Listing
February 2019

Development of a clinical practice guideline for orthodontic retention.

Orthod Craniofac Res 2019 Feb 16. Epub 2019 Feb 16.

Department of Dentistry, section of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen, The Netherlands.

Objectives: To develop a clinical practice guideline (CPG) for orthodontic retention (OR).

Materials And Methods: The CPG was developed according to the AGREE II instrument and EBRO (Dutch methodology for evidence-based guideline development). Reporting was done according the RIGHT statement. Read More

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http://dx.doi.org/10.1111/ocr.12302DOI Listing
February 2019

Deprescribing cholinesterase inhibitors and memantine in dementia: guideline summary.

Med J Aust 2019 Feb 16. Epub 2019 Feb 16.

NHMRC Cognitive Decline Partnership Centre, Kolling Institute of Medical Research, Northern Clinical School, University of Sydney, Sydney, NSW.

Introduction: Cholinesterase inhibitors (ChEIs) and memantine are medications used to treat the symptoms of specific types of dementia. Their benefits and harms can change over time, particularly during long term use. Therefore, appropriate use of ChEIs and memantine involves both prescribing these medications to individuals who are likely to benefit, and deprescribing (withdrawing) them from individuals when the risks outweigh the benefits. Read More

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http://dx.doi.org/10.5694/mja2.50015DOI Listing
February 2019

Discrimination of osteoporosis-related vertebral fractures by DXA-derived 3D measurements: a retrospective case-control study.

Osteoporos Int 2019 Feb 15. Epub 2019 Feb 15.

CETIR Grup Mèdic, Barcelona, Spain.

A retrospective case-control study assessing the association of DXA-derived 3D measurements with osteoporosis-related vertebral fractures was performed. Trabecular volumetric bone mineral density was the measurement that best discriminates between fracture and control groups.

Introduction: The aim of the present study was to evaluate the association of DXA-derived 3D measurements at the lumbar spine with osteoporosis-related vertebral fractures. Read More

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http://link.springer.com/10.1007/s00198-019-04894-y
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http://dx.doi.org/10.1007/s00198-019-04894-yDOI Listing
February 2019
1 Read

Real world preventative drug management of migraine among Spanish neurologists.

J Headache Pain 2019 Feb 15;20(1):19. Epub 2019 Feb 15.

Headache Unit, Neurology Department, Hospital Universitario Clínico de Valladolid, Avda. Ramón y Cajal 3, 47005, Valladolid, Spain.

Background: Many different preventatives have showed efficacy in the treatment of migraine. National guidelines differ in their recommendations and patients' characteristics are usually taken into account in their selection. In Spain, real life use of preventive therapies seems to be heterogeneous. Read More

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https://thejournalofheadacheandpain.biomedcentral.com/articl
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http://dx.doi.org/10.1186/s10194-019-0971-6DOI Listing
February 2019
1 Read

Roadmap for the radial: Should we stop for directions?

Catheter Cardiovasc Interv 2019 Feb;93(3):E195-E196

MS Hershey Medical Center, College of Medicine, Heart & Vascular Institute, Penn State University, Hershey, PA.

Regimented use of radial artery angiography prior to ST-segment myocardial infarction (STEMI) intervention may improve complication rates and can be associated with improved procedural success, procedural time, and reduction in access-site bleeding. Routine radial artery angiography may improve procedural quality without increase in procedural time or contrast use. Regardless of whether universal or selective radial angiography is best practice, angiography is an important tool to use for efficient radial access. Read More

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http://dx.doi.org/10.1002/ccd.28058DOI Listing
February 2019

A tumor board report of an 83-year-old woman with stage IB grade 3 endometrioid endometrial adenocarcinoma.

Curr Probl Cancer 2019 Feb 7. Epub 2019 Feb 7.

Brigham and Women's Hospital, Department of Gynecologic Oncology, Boston, Massachusetts; Dana Farber Cancer Institute, Department of Gynecologic Oncology, Boston, Massachusetts.

An 83-year-old woman presented with postmenopausal bleeding ultimately leading to surgery and a final diagnosis of stage IB grade 3 endometrioid endometrial adenocarcinoma. The tumor board reviewed current literature regarding the efficacy of sentinel lymph node dissection in appropriately allocating stage in high-grade endometrial cancer. The optimal role of adjuvant treatment in this setting is unclear. Read More

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http://dx.doi.org/10.1016/j.currproblcancer.2019.01.006DOI Listing
February 2019

Characterization of Patients With Geographic Atrophy in Routine Clinical Practice.

Ophthalmic Surg Lasers Imaging Retina 2019 Feb;50(2):93-98

Background And Objective: Geographic atrophy (GA) affects millions of patients with age-related macular degeneration (AMD) worldwide, leading to significant, irreversible visual impairment. This study aims to characterize the visual impairment of patients with GA in a routine clinical practice.

Patients And Methods: This single-center, cross-sectional study used a novel natural language processing to select 1,045 GA cases utilizing the macula examination records from 19,359 patients with AMD. Read More

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http://dx.doi.org/10.3928/23258160-20190129-05DOI Listing
February 2019

Storytelling: How We Learn.

Authors:
Anne Katz

Oncol Nurs Forum 2019 Mar;46(2):141-142

CancerCare Manitoba.

The best conference presentations tell a story with an interesting introduction, details in the middle, and a conclusion that leads to new research, questions or answers about practice, and perhaps further research on the topic. So, too, do journal articles, and this publication is dependent on the rigors of quality research to tell stories about our patients and their experiences and make suggestions on how we can effect change. Read More

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http://dx.doi.org/10.1188/19.ONF.141-142DOI Listing

Anesthesia Exposure in Children: Practitioners Respond to the 2016 FDA Drug Safety Communication.

J Neurosurg Anesthesiol 2019 Jan;31(1):129-133

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA.

In December 2016, the US Food and Drug Administration (FDA) issued a drug safety warning stating that 11 commonly used anesthetic and sedative medications had potential neurotoxic effects when used in children under the age of 3 years and in pregnant women during the third trimester. A panel presentation at the sixth biennial Pediatric Anesthesia Neurodevelopmental Assessment (PANDA) symposium addressed the FDA announcement in a session entitled "Anesthesia Exposure in Children During Surgical and Non-Surgical Procedures: How Do We Respond to the 2016 FDA Drug Safety Communication?" Panelists included representatives from pediatric anesthesiology, obstetrics, pediatric surgery, and several pediatric surgical subspecialties. Each panelist was asked to address the following questions: How has the FDA labelling change affected your clinical practice including patient discussions, timing, and frequency of procedures? Has your professional society provided any guidelines for this discussion? Has there been any discussion of this topic at your national meetings? The panelists provided important perspectives specific to each specialty, which generated a lively discussion and a detailed response from the Deputy Director of the Division of Anesthesia and Addiction of the FDA describing the FDA procedures that led to this drug safety warning. Read More

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http://dx.doi.org/10.1097/ANA.0000000000000545DOI Listing
January 2019

What's important in AAC decision making for children? Evidence from a best-worst scaling survey.

Augment Altern Commun 2019 Feb 15:1-15. Epub 2019 Feb 15.

b Faculty of Health Psychology and Social Care , Manchester Metropolitan University , Manchester , UK.

The choice of which AAC device to provide for a child can have long lasting consequences, but little is known about the decision-making of AAC professionals who make recommendations in this context. A survey was conducted with AAC professionals using best-worst scaling methodology examining what characteristics of children and attributes of AAC devices are considered most important in decision-making. A total of 19 child characteristics and 18 device attributes were selected by the authors from lists generated from literature reviews and from focus groups with AAC professionals, people who use AAC, and other stakeholders. Read More

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http://dx.doi.org/10.1080/07434618.2018.1561750DOI Listing
February 2019

Current Concepts and Best Evidence on Strategies to Prevent Dental Erosion.

Compend Contin Educ Dent 2019 Feb;40(2):80-86; quiz 87

Professor, Division of Operative Dentistry, Department of General Dentistry, University of Maryland School of Dentistry, Baltimore, Maryland.

Dental erosion is a multifactorial condition associated with chemical, biological, and behavioral factors whereby a non-bacterial chemical process leads to an irreversible loss of dental structure. Consequences of this erosive process include painful sensitivity, susceptibility to further erosion, mechanical wear, changes in occlusion, exposure of dental pulp, and poor esthetics. Substantial evidence has revealed new insights to diagnosing early stages of dental erosion and enabling novel preventive approaches to control its progression. Read More

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February 2019

Pilot study of a novel multi-functional noninvasive prenatal test on fetus aneuploidy, copy number variation, and single-gene disorder screening.

Mol Genet Genomic Med 2019 Feb 14:e597. Epub 2019 Feb 14.

The Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Background: The noninvasive prenatal testing (NIPT) has been successfully used in the clinical screening of fetal trisomy 13, 18, and 21 in the last few years and researches on detecting sub-chromosomal copy number variations (CNVs) and monogenic diseases are also in progress. To date, multiple tests are needed in order to complete a full set of fetus disorder screening, which is costly and time consuming. Therefore, an integrated 3-in-1 NIPT approach will be in great demand by routine clinical practice in the near future. Read More

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http://dx.doi.org/10.1002/mgg3.597DOI Listing
February 2019

Approach to sexual dysfunction in women with cancer.

Int J Gynecol Cancer 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.

Sexual dysfunction in female cancer patients remains under-diagnosed and under-treated. As sexual dysfunction is becoming an increasingly common side effect of cancer treatments, it is imperative for healthcare providers and especially gynecologic oncologists to include a comprehensive evaluation of sexual health as a routine part of the workup of such patients. Although most oncologists are not experienced in treating sexual dysfunctions, simple tools can be incorporated into clinical practice to improve the management of these conditions. Read More

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http://dx.doi.org/10.1136/ijgc-2018-000096DOI Listing
February 2019

Causal inference for clinicians.

BMJ Evid Based Med 2019 Feb 14. Epub 2019 Feb 14.

Department of Epidemiology, Lady Davis Institute for Medical Research, Montreal, Quebec, Canada.

Evidence-based medicine (EBM) calls on clinicians to incorporate the 'best available evidence' into clinical decision-making. For decisions regarding treatment, the best evidence is that which determines the causal effect of treatments on the clinical outcomes of interest. Unfortunately, research often provides evidence where associations are not due to cause-and-effect, but rather due to non-causal reasons. Read More

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http://dx.doi.org/10.1136/bmjebm-2018-111069DOI Listing
February 2019

Implementing a best-practice model of gestational diabetes mellitus care in dietetics: a qualitative study.

BMC Health Serv Res 2019 Feb 14;19(1):122. Epub 2019 Feb 14.

Cairns and Hinterland Hospital and Health Service and College of Healthcare Sciences, James Cook University, Cairns, 4870, Australia.

Background: Translating research into clinical practice is challenging for health services. Emerging approaches in implementation science recognise the need for a theory-driven approach to identify and overcome barriers to guideline adherence. However, many clinicians do not have the capacity, confidence, or expertise to realise change in their local settings. Read More

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http://dx.doi.org/10.1186/s12913-019-3947-yDOI Listing
February 2019

Comparison of CPG's for the diagnosis, prognosis and management of non-specific neck pain: a systematic review.

BMC Musculoskelet Disord 2019 Feb 14;20(1):81. Epub 2019 Feb 14.

Department of Health Science, McMaster University, Hamilton, ON, Canada.

Background: Neck pain (NP) is a very common musculoskeletal condition with potential for a high burden in disability and length of disorder. Clinical practice guidelines (CPG) give recommendations to clinicians for providing optimal care for patients however best practice recommendations are often contradictory. The purpose for this review was to conduct a SR of CPGs to assess the management recommendations for NP (diagnosis, treatment, prognosis, imaging). Read More

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http://dx.doi.org/10.1186/s12891-019-2441-3DOI Listing
February 2019

Predicting patient use of general practice services in Australia: models developed using national cross-sectional survey data.

BMC Fam Pract 2019 Feb 14;20(1):28. Epub 2019 Feb 14.

(Then) Family Medicine Research Centre, School of Public Health, University of Sydney, Camperdown, Australia.

Background: The ageing population and increasing prevalence of multimorbidity place greater resource demands on the health systems internationally. Accurate prediction of general practice (GP) services is important for health workforce planning. The aim of this research was to develop a parsimonious model that predicts patient visit rates to general practice. Read More

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http://dx.doi.org/10.1186/s12875-019-0914-yDOI Listing
February 2019

A Laboratory Study on Non-Invasive Soil Water Content Estimation Using Capacitive Based Sensors.

Sensors (Basel) 2019 Feb 5;19(3). Epub 2019 Feb 5.

Department of Infrastructure Engineering, School of Engineering, The University of Melbourne, Parkville, VIC 3010, Australia.

Soil water content is an important parameter in many engineering, agricultural and environmental applications. In practice, there exists a need to measure this parameter rather frequently in both time and space. However, common measurement techniques are typically invasive, time-consuming and labour-intensive, or rely on potentially risky (although highly regulated) nuclear-based methods, making frequent measurements of soil water content impractical. Read More

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http://dx.doi.org/10.3390/s19030651DOI Listing
February 2019

Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder.

Eur Psychiatry 2019 Feb 11;58:19-26. Epub 2019 Feb 11.

Rita Levi Montalcini Department of Neuroscience, University of Turin, Italy and San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.

Background: The duration of untreated illness (DUI) is a potentially modifiable parameter associated with worst prognosis in several psychiatric disorders, but poorly investigated in Obsessive-Compulsive Disorder (OCD). Our aims were to estimate the mean DUI in a large sample of individuals with OCD and its impact on response to the first ever adequate SRI treatment.

Methods: We retrospectively examined records of 251 patients with OCD (SCID-I, DSM-IV) who referred to our Department and were prospectively and naturalistically treated according to International Guidelines. Read More

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http://dx.doi.org/10.1016/j.eurpsy.2019.01.017DOI Listing
February 2019

The optimal use of imaging in Radiation Therapy for lymphoma - Guidelines from the International Lymphoma Radiation Oncology Group (ILROG).

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Radiation therapy (RT) for the management of lymphomas has evolved over the past decades. Large extended or involved fields have been replaced by smaller involved site or nodal volumes. Currently, customized plans are created for each individual patient that encompass only the areas involved by disease. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.001DOI Listing
February 2019

Cardiac Function After Radiotherapy for Breast Cancer.

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30, 001, 9700 RB Groningen, The Netherlands. Electronic address:

Purpose: The main purpose of this study was to test the hypothesis that incidental cardiac irradiation is associated with changes in cardiac function in breast cancer (BC) survivors treated with radiotherapy (RT).

Methods And Materials: We conducted a cross-sectional study consisting of 109 BC survivors treated with RT between 2005 and 2011. The endpoint was cardiac function, assessed by echocardiography. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.003DOI Listing
February 2019

Introduction to a new Special Series for the Journal of Pain and Symptom Management - Science in Action: Evidence and opportunities for palliative care across diverse populations and care settings.

J Pain Symptom Manage 2019 Feb 11. Epub 2019 Feb 11.

Director of Quality and Research, American Academy of Hospice and Palliative Medicine (AAHPM), Chicago, IL.

Practices to optimize palliative care delivery and new opportunities in which to integrate palliative care vary across populations and care settings. Systematic reviews are an efficient and methodologically rigorous approach to summarize existing research to identify both evidence-based best-practices as well as new areas for future research and clinical practice. This is the introduction to a special series of articles in which members of the AAHPM Research Committee report the results of circumscribed systematic reviews which in a specific population or care setting seek to: (a) summarize existing evidence for optimal palliative care practices or (b) identify opportunities where better palliative care delivery could improve patient and/or family outcomes. Read More

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http://dx.doi.org/10.1016/j.jpainsymman.2019.02.005DOI Listing
February 2019

A comparison of patients managed in specialist versus non-specialist inpatient rehabilitation units in Australia.

Disabil Rehabil 2019 Feb 14:1-8. Epub 2019 Feb 14.

c Australasian Rehabilitation Outcomes Centre , Wollongong , Australia.

Aim: To compare the rehabilitation of patients with brain and spinal cord injury in specialist rehabilitation units and non-specialist rehabilitation units in Australia over a 10-year period.

Method: A retrospective cohort study design was used. Epidemiological descriptive analysis was used to examine inpatient rehabilitation data held in the Australasian Rehabilitation Outcomes Centre Registry Database at four discrete time points: 2007, 2010, 2013 and 2016. Read More

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http://dx.doi.org/10.1080/09638288.2019.1568592DOI Listing
February 2019

Hypertensive ocular disease in cats: A guide to fundic lesions to facilitate early diagnosis.

Authors:
Jenny Carter

J Feline Med Surg 2019 Jan;21(1):35-45

Auckland, New Zealand.

Practical Relevance:: Systemic hypertension is common in older cats and can result in damage to organs with a rich arteriolar supply such as the eyes, kidneys, myocardium and brain. Hypertensive disease in these organs is known as target organ damage (TOD). Disease in the eye resulting from hypertension is the most easily identifiable form of TOD and can often be the reason the cat is presented to the veterinarian. Read More

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http://journals.sagepub.com/doi/10.1177/1098612X18818668
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http://dx.doi.org/10.1177/1098612X18818668DOI Listing
January 2019
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Determining Best Practices for Management of Bacteriuria in Spinal Cord Injury: Protocol for a Mixed-Methods Study.

JMIR Res Protoc 2019 Feb 14;8(2):e12272. Epub 2019 Feb 14.

Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, United States.

Background: Bacteriuria, either asymptomatic (ASB) or symptomatic, urinary tract infection (UTI), is common in persons with spinal cord injury (SCI). Current Veterans Health Administration (VHA) guidelines recommend a screening urinalysis and urine culture for every veteran with SCI during annual evaluation, even when asymptomatic, which is contrary to other national guidelines. Our preliminary data suggest that a positive urine culture (even without signs or symptoms of infection) drives antibiotic use. Read More

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https://www.researchprotocols.org/2019/2/e12272/
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http://dx.doi.org/10.2196/12272DOI Listing
February 2019
2 Reads

Yvonne M. Agazarian (1929-2017).

Authors:
Susan P Gantt

Am Psychol 2019 Feb-Mar;74(2):259

Emory University School of Medicine.

Presents an obituary for Yvonne M. Agazarian (1929-2017). Agazarian was a brilliant theoretician, clinician, and teacher who devoted her life to the development of a theory of living human systems (TLHS) and its systems-centered therapy and training (SCT). Read More

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http://dx.doi.org/10.1037/amp0000332DOI Listing
February 2019

Use of a combination strategy to improve neuroprotection and neuroregeneration in a rat model of acute spinal cord injury.

Neural Regen Res 2019 Jun;14(6):1060-1068

Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México Campus Norte, Huixquilucan, Edo. de México, México; Centro de Investigación del Proyecto CAMINA A.C.; Ciudad de México, México.

Spinal cord injury is a very common pathological event that has devastating functional consequences in patients. In recent years, several research groups are trying to find an effective therapy that could be applied in clinical practice. In this study, we analyzed the combination of different strategies as a potential therapy for spinal cord injury. Read More

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http://dx.doi.org/10.4103/1673-5374.250627DOI Listing

Patient stakeholder engagement in research: A narrative review to describe foundational principles and best practice activities.

Health Expect 2019 Feb 13. Epub 2019 Feb 13.

Division of Hospital Medicine, University of California San Francisco, San Francisco, California.

Background: Health research is evolving to include patient stakeholders (patients, families and caregivers) as active members of research teams. Frameworks describing the conceptual foundations underlying this engagement and strategies detailing best practice activities to facilitate engagement have been published to guide these efforts.

Objective: The aims of this narrative review are to identify, quantify and summarize (a) the conceptual foundational principles of patient stakeholder engagement in research and (b) best practice activities to support these efforts. Read More

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http://dx.doi.org/10.1111/hex.12873DOI Listing
February 2019
3.410 Impact Factor

Point-Of-Care Testing Curriculum and Accreditation for Public Health-Enabling Preparedness, Response, and Higher Standards of Care at Points of Need.

Front Public Health 2018 29;6:385. Epub 2019 Jan 29.

Point-of-Care Testing Center for Teaching and Research, Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.

To develop awareness of benefits of point-of-care testing (POCT) education in schools of public health, to identify learning objectives for teaching POCT, to enable public health professionals and emergency responders to perform evidence-based diagnosis and triage effectively and efficiently at points of need, and to better improve future standards of care for public health practice, including in limited-resource settings and crisis situations. We surveyed all U.S. Read More

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https://www.frontiersin.org/article/10.3389/fpubh.2018.00385
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http://dx.doi.org/10.3389/fpubh.2018.00385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361824PMC
January 2019
2 Reads

Concordance Among Bioelectrical Impedance Analysis Measures of Percent Body Fat in Athletic Young Adults.

Int J Exerc Sci 2019 1;12(4):324-331. Epub 2019 Jan 1.

Health and Exercise Science Department, Lenoir-Rhyne University, Hickory, NC, USA.

The purpose of this investigation was to determine the agreement among three bioelectrical impedance analysis devices (BIA) in athletic young adults. Fifty-one participants (26 men and 25 women) were assessed for percent body fat (PBF) using an arm-to-arm bipolar single-frequency device (ABIA), a leg-to-leg single-frequency device (LBIA), and an octopolar multi-frequency BIA device (MFBIA). PBF was measured with the three devices in a randomized, counterbalanced order. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355131PMC
January 2019

Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study.

Front Pharmacol 2019 29;10:31. Epub 2019 Jan 29.

National Institutes for Food and Drug Control, Beijing, China.

Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success rates of new drug development, we need to have a comprehensive understanding about the relationship between the structure of cephalosporins and the toxicity that it induces at an early stage. Read More

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http://dx.doi.org/10.3389/fphar.2019.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361752PMC
January 2019

Embracing Cultural Diversity: Meaningful Engagement for Older Adults With Advanced Dementia in a Residential Care Setting.

Am J Occup Ther 2018 Nov/Dec;72(6):7206205090p1-7206205090p8

Helen Buchanan, BSc(OT), MSc(OT), PhD, is Associate Professor, Department of Health and Rehabilitation Sciences, Division of Occupational Therapy, University of Cape Town, Cape Town, South Africa;

Providing person-centered care (PCC) that focuses on meaningful engagement in residential care settings for older adults with moderate to advanced dementia is an internationally recognized challenge. In this study, we aimed to identify best-practice scenarios for supporting older adults with moderate to advanced dementia from culturally and linguistically diverse backgrounds who lived in care facilities. A mixed-methods study with a concurrent triangulation strategy was adopted. Read More

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http://dx.doi.org/10.5014/ajot.2018.027292DOI Listing
February 2019

Incidental finding of Zinner syndrome in a Greek military recruit: a case report of a rare clinical entity.

Mil Med Res 2019 Feb 14;6(1). Epub 2019 Feb 14.

Department of Urology, 424 General Military Hospital of Thessaloniki, 56429, Thessaloniki, Greece.

Background: Zinner syndrome represents a rare congenital malformation of the urinary tract. It comprises a constellation of Wolffian duct anomalies and is almost exclusively encountered as a classic triad of seminal vesicle cysts, ejaculatory duct obstruction and renal agenesis. Patients can be either asymptomatic or symptomatic. Read More

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http://dx.doi.org/10.1186/s40779-019-0194-9DOI Listing
February 2019

Enhanced Auditory Steady-State Response Using an Optimized Chirp Stimulus-Evoked Paradigm.

Sensors (Basel) 2019 Feb 12;19(3). Epub 2019 Feb 12.

Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.

: It has been reported recently that gamma measures of the electroencephalogram (EEG) might provide information about the candidate biomarker of mental diseases like schizophrenia, Alzheimer's disease, affective disorder and so on, but as we know it is a difficult issue to induce visual and tactile evoked responses at high frequencies. Although a high-frequency response evoked by auditory senses is achievable, the quality of the recording response is not ideal, such as relatively low signal-to-noise ratio (SNR). Recently, auditory steady-state responses (ASSRs) play an essential role in the field of basic auditory studies and clinical uses. Read More

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http://www.mdpi.com/1424-8220/19/3/748
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http://dx.doi.org/10.3390/s19030748DOI Listing
February 2019
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[Vaccination in Germany - Recommendations of STIKO].

Authors:
Thomas Mertens

Dtsch Med Wochenschr 2019 Feb 13;144(4):239-243. Epub 2019 Feb 13.

The epidemiological effect of vaccination is that it primarily reduces the incidence and prevalence of infectious agents and diseases, providing ideal conditions (also from an economic point of view) for prevention. Goal of vaccination is first the individual protection. Other goals may be "herd immunity", regional repression and global extinction. Read More

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http://dx.doi.org/10.1055/a-0479-3890DOI Listing
February 2019

elPrep 4: A multithreaded framework for sequence analysis.

PLoS One 2019 13;14(2):e0209523. Epub 2019 Feb 13.

ExaScience Life Lab, IMEC, Leuven, Belgium.

We present elPrep 4, a reimplementation from scratch of the elPrep framework for processing sequence alignment map files in the Go programming language. elPrep 4 includes multiple new features allowing us to process all of the preparation steps defined by the GATK Best Practice pipelines for variant calling. This includes new and improved functionality for sorting, (optical) duplicate marking, base quality score recalibration, BED and VCF parsing, and various filtering options. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209523PLOS
February 2019

Radcliffe ARFID Workgroup: Toward operationalization of research diagnostic criteria and directions for the field.

Int J Eat Disord 2019 Feb 13. Epub 2019 Feb 13.

Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Since its introduction to the psychiatric nomenclature in 2013, research on avoidant/restrictive food intake disorder (ARFID) has proliferated highlighting lack of clarity in how ARFID is defined.

Method: In September 2018, a small multi-disciplinary pool of international experts in feeding disorder and eating disorder clinical practice and research convened as the Radcliffe ARFID workgroup to consider operationalization of DSM-5 ARFID diagnostic criteria to guide research in this disorder.

Results: By consensus of the Radcliffe ARFID workgroup, ARFID eating is characterized by food avoidance and/or restriction, involving limited volume and/or variety associated with one or more of the following: weight loss or faltering growth (e. Read More

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http://dx.doi.org/10.1002/eat.23042DOI Listing
February 2019
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The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm.

Diabetes Ther 2019 Feb 13. Epub 2019 Feb 13.

Diabetes Research Centre, University of Leicester, Leicester, UK.

There is currently a worldwide epidemic of type 2 diabetes (T2D) that is predicted to increase substantially in the next few years. With 80% of the global T2D population living in low to middle-income countries, there are issues with cost and of access to appropriate medicines. The objective of this symposium was to provide an overview of the efficacy and safety of glucose-lowering drugs, focussing in particular on sulfonylureas (SUs) in patients with T2D using data taken from both randomised controlled trials (RCTs) and real-world studies, the application of strategies to ensure optimal patient adherence and clinical outcomes, and the optimal use of SUs in terms of dose adjustment and agent choice to ensure the best clinical outcome. Read More

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http://dx.doi.org/10.1007/s13300-019-0573-yDOI Listing
February 2019

Acoustic Voice Quality Index - AVQI for brazilian portuguese speakers: analysis of different speech material.

Codas 2019 Feb 11;31(1):e20180082. Epub 2019 Feb 11.

Universidade Federal de São Paulo - Unifesp - São Paulo (SP), Brasil.

Purpose: This study aimed to verify the best speech material for the AVQI for Brazilian Portuguese language and identify the best validity results between the auditory perceptual judgment (APJ) and the AVQI score on different speech materials.

Methods: We recorded voice samples of 50 individuals (dysphonic and vocally healthy) of several continuous speech (cs) variants (i.e. Read More

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http://dx.doi.org/10.1590/2317-1782/20182018082DOI Listing
February 2019
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Measurement properties of instruments to assess mental function during activity and participation in individuals surviving traumatic brain injury: A systematic review protocol.

Scand J Occup Ther 2019 Feb 13:1-5. Epub 2019 Feb 13.

a Department of Physiotherapy and Occupational Therapy , Aarhus University Hospital , Aarhus , Denmark.

Background: Most studies assessing mental function in individuals with traumatic brain injury (TBI) assess the impairments through pen and paper tests. However, weak correlation has been found between the results from pen and paper tests and the results from performance-based tests during activity and participation.

Objective: To investigate measurement properties of performance-based instruments that are used to assess mental function during activity and participation in individuals with a TBI. Read More

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http://dx.doi.org/10.1080/11038128.2018.1563630DOI Listing
February 2019

Bilateral maxillary augmentation using CAD/CAM manufactured allogenic bone blocks for restoration of congenitally missing teeth: A case report.

J Esthet Restor Dent 2019 Feb 12. Epub 2019 Feb 12.

Private Practice, Munich, Bavaria, Germany.

Objective: Various biomaterials have been successfully applied in alveolar bone regeneration, however, the reconstruction of extensive osseous defects remains challenging and is often unfeasible with granular grafting materials. Several studies have outlined allogenic bone blocks as valid alternative to autologous block grafting.

Clinical Considerations: In this report, we demonstrate the regeneration of two large osseous defects in the maxilla with allogenic bone blocks made from human donor bone. Read More

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http://dx.doi.org/10.1111/jerd.12454DOI Listing
February 2019

Thromboprophylaxis for varicose vein procedures - A national survey.

Phlebology 2019 Feb 12:268355519828931. Epub 2019 Feb 12.

Department of Vascular Surgery, Royal Victoria Hospital, Belfast, UK.

Background: Venous thromboembolism is rare following varicose vein ablation procedures, but uncertainty about its incidence combined with a lack of evidence-based clinical guidelines regarding thromboprophylaxis has led to debate about best practice. We conducted a national survey to investigate current practice among Irish vascular surgeons.

Methods: An anonymous online questionnaire was emailed to all members of the Irish Association of Vascular Surgeons and the Northern Ireland Vascular Society. Read More

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http://dx.doi.org/10.1177/0268355519828931DOI Listing
February 2019

A review of exhaled breath key role in lung cancer diagnosis.

J Breath Res 2019 Feb 12. Epub 2019 Feb 12.

Department of Bio-Engineering, Politecnico di Milano, Pizza L Da Vinci ,32, 20133 Milano, Milan, ITALY.

One of the main causes of the high mortality rate in lung cancer is the late-stage tumor detection. Early diagnosis is therefore essential to increase the chances of obtaining an effective treatment quickly thus increasing the survival rate. Current screening techniques are based on imaging, with low dose computed tomography (LDCT) as the pivotal approach. Read More

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http://dx.doi.org/10.1088/1752-7163/ab0684DOI Listing
February 2019
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Facilitators and barriers to brokering between research and care by senior clinical-scientists in general practice and elderly care medicine.

Educ Prim Care 2019 Feb 12:1-8. Epub 2019 Feb 12.

a Julius Centre , University Medical Centre Utrecht, Utrecht University , Utrecht , The Netherlands.

Background: Clinician-scientists (CSs) are physicians who work in daily care and have an academic role in research or education. They may act as knowledge brokers and help to connect research and clinical practice. There is no data available on CSs' brokering activities and the perceived barriers and facilitators to optimising their role in general practice (GP) and elderly care medicine (EM). Read More

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http://dx.doi.org/10.1080/14739879.2019.1570349DOI Listing
February 2019
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Fossils with Feathers and Philosophy of Science.

Syst Biol 2019 Feb 11. Epub 2019 Feb 11.

Campbell Geology Museum, Clemson University, Clemson, SC.

The last half century of paleornithological research has transformed the way that biologists perceive the evolutionary history of birds. This transformation has been driven, since 1969, by a series of exciting fossil discoveries combined with intense scientific debate over how best to interpret these discoveries. Ideally, as evidence accrues and results accumulate, interpretive scientific agreement forms. Read More

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http://dx.doi.org/10.1093/sysbio/syz010DOI Listing
February 2019
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Risk-Informed Intervention: Using Intimate Partner Violence Risk Assessment within an Evidence-Based Practice Framework.

Soc Work 2019 Feb 7. Epub 2019 Feb 7.

Jill Theresa Messing, PhD, MSW, is associate professor, School of Social Work, Arizona State University, 411 N Central Avenue, Suite 800, Phoenix, AZ 85004; e-mail:

Intimate partner violence (IPV) is a pervasive problem in the United States. IPV is often repetitive and may escalate; in a small number of cases, IPV leads to homicide. This article presents an evidence-based practice (EBP) model for risk-informed social work intervention with survivors and perpetrators of IPV. Read More

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http://dx.doi.org/10.1093/sw/swz009DOI Listing
February 2019
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