163,332 results match your criteria Best Practice & Research: Clinical Haematology[Journal]


Analysis of States' Barriers to and Progress Toward Implementation of Health and Safety Policies for Secondary School Athletics.

J Athl Train 2019 Apr 24. Epub 2019 Apr 24.

Korey Stringer Institute, Department of Kinesiology, University of Connecticut, Storrs.

Context: Implementation of health and safety best practices for the leading causes of sudden death and catastrophic injury has been shown to mitigate risk. However, to our knowledge, no authors have examined progress toward health and safety policy implementation at the state level.

Objective: To investigate the progress made by state secondary school leaders in developing and implementing health and safety policies (ie, exertional heat stroke, sudden cardiac arrest, concussion, emergency action plans) and to explore perceived barriers to and strategies for implementation. Read More

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http://dx.doi.org/10.4085/1062-6050-28-18DOI Listing

Efficacy of Integrated Exposure Therapy vs Integrated Coping Skills Therapy for Comorbid Posttraumatic Stress Disorder and Alcohol Use Disorder: A Randomized Clinical Trial.

JAMA Psychiatry 2019 Apr 24. Epub 2019 Apr 24.

VA San Diego Healthcare System, San Diego, California.

Importance: Co-occurrence of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) is common and associated with psychiatric and functional problems. Understanding whether exposure therapy is tolerable and efficacious for treating PTSD and AUD is critical to ensure that best practice treatments are available.

Objective: To compare the efficacy of integrated (ie, targeting both PTSD and alcohol use) prolonged exposure (I-PE) therapy with present-centered integrated coping skills (I-CS) therapy, a more commonly available treatment, in reducing PTSD symptoms and alcohol use. Read More

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http://dx.doi.org/10.1001/jamapsychiatry.2019.0638DOI Listing

Biobank Continuity Management: A Survey of Biobank Professionals.

Biopreserv Biobank 2019 Apr 24. Epub 2019 Apr 24.

Regulatory and Quality Sciences, University of Southern California (USC), USC School of Pharmacy, Los Angeles, California.

Academic biobanks face challenges that call for continuity and disaster planning. However, current regulations do not require such planning, so it is unclear if and how biobanks have prepared themselves to deal with future crises. This exploratory study used mixed methods to understand the state of continuity planning in U. Read More

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http://dx.doi.org/10.1089/bio.2018.0142DOI Listing

Using two models of workplace facilitation to create conditions for development of a person-centred culture: a participatory action research study.

J Clin Nurs 2019 Apr 24. Epub 2019 Apr 24.

Queen Margaret University, Edinburgh.

Aims And Objectives: To examine facilitation in workplace learning where nurses are focused on creating person-centred cultures; to provide a framework for novice and proficient facilitators/practitioners to learn in and from their own workplaces and practices; to provide the conditions where practitioners can gain an understanding of the culture and context within their own workplace.

Background: Evidence suggests that person-centred cultures depend on purposeful, facilitated practice based learning activities. For person-centredness to become more meaningful to nursing leaders in their daily work, focus must be placed on their acquisition and use of facilitation skills. Read More

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http://dx.doi.org/10.1111/jocn.14897DOI Listing

A new biomechanical glaucoma factor to discriminate normal eyes from normal pressure glaucoma eyes.

Acta Ophthalmol 2019 Apr 24. Epub 2019 Apr 24.

Department of Ophthalmology, Medical Faculty Carl Gustav Carus, Technische Universität, Dresden, Germany.

Background: To test the ability of the newly calculated Dresden biomechanical glaucoma factor (DBGF) based on dynamic corneal response (DCR) deformation and corneal thickness parameters, to discriminate between healthy and normal pressure glaucoma (NPG) eyes.

Methods: Seventy healthy and 70 NPG patients of Caucasian origin were recruited for this multicentre cross-sectional pilot study, which included both eyes for analysis. Logistic regression analysis with generalized estimating equation (GEE) models to account for correlations between eyes and a threefold cross-validation were performed to determine the optimal combination of Corvis ST parameters in order to separate normal from NPG eyes. Read More

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http://dx.doi.org/10.1111/aos.14115DOI Listing

Budget Impact Analysis of Cancer Screening: A Methodological Review.

Appl Health Econ Health Policy 2019 Apr 24. Epub 2019 Apr 24.

Department of Public Health, Health Services Research and Health Technology Assessment, Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT-University for Health Sciences, Medical Informatics and Technology, Eduard-Wallnoefer-Zentrum 1, 6060, Hall in Tyrol, Austria.

Background: Budget impact analyses (BIAs) describe changes in intervention- and disease-related costs of new technologies. Evidence on the quality of BIAs for cancer screening is lacking.

Objectives: We systematically reviewed the literature and methods to assess how closely BIA guidelines are followed when BIAs are performed for cancer-screening programs. Read More

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http://dx.doi.org/10.1007/s40258-019-00475-6DOI Listing

Efficacy and safety of the pharmacotherapy used in the management of hyperkalemia: a systematic review.

Pharm Pract (Granada) 2019 Jan-Mar;17(1):1361. Epub 2019 Mar 4.

Department of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP). Araraquara, SP (Brazil).

Background: Although the management of hyperkalemia follows expert guidelines, treatment approaches are based on traditionally accepted practice standards. New drugs have been assessed such as sodium zirconium cyclosilicate and patiromer; however, their safety and efficacy or effectiveness have not yet been compared to traditional pharmacotherapy.

Objective: The present systematic review had the purpose to evaluate the efficacy, effectiveness, and safety of hyperkalemia pharmacotherapies. Read More

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http://dx.doi.org/10.18549/PharmPract.2019.1.1361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463413PMC

Comparative Efficacy and Tolerability of Neoadjuvant Immunotherapy Regimens for Patients with HER2-Positive Breast Cancer: A Network Meta-Analysis.

J Oncol 2019 19;2019:3406972. Epub 2019 Mar 19.

Department of Central Laboratory, Shenzhen Hospital, Beijing University of Chinese Medicine, Shenzhen, China.

This network meta-analysis addresses the need for evidence-based best-practice treatment regimens for HER2-positive breast cancer. We compared the relative efficacy and tolerability of currently available HER2-positive neoadjuvant immunotherapy regimens based on systematic searches of available randomized controlled trials (RCTs) data. Based on intention-to-treat principle, pathological complete response (pCR), overall serious adverse events (SAEs), and breast-conserving surgery (BCS) rate were analyzed using random-effect, Bayesian network meta-analysis, and standard pairwise meta-analysis. Read More

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http://dx.doi.org/10.1155/2019/3406972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444249PMC

Chronic rhinosinusitis: a qualitative study of patient views and experiences of current management in primary and secondary care.

BMJ Open 2019 Apr 23;9(4):e022644. Epub 2019 Apr 23.

Norwich Medical School, University of East Anglia, Norwich, UK.

Objectives: To explore patient views and perspectives of current management of chronic rhinosinusitis (CRS) in primary and secondary care.

Design: Semistructured qualitative telephone interviews as part of the MACRO programme (Defining best Management for Adults with Chronic RhinOsinusitis).

Setting: Primary care and secondary care ear, nose and throat outpatient clinics in the UK. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-022644DOI Listing

The value of international volunteers experience to the NHS.

Global Health 2019 Apr 23;15(1):31. Epub 2019 Apr 23.

Office of Health Economics, Southside 7th floor, 105 Victoria Street, London, SW1E 6QT, UK.

Background: Global Engagement works with health partnerships to establish workforce and educational translation on a global scale to support the National Health Service (NHS). There is growing evidence on how international experiences (through volunteering, exchanges and placements) benefit the NHS through an innovative workforce that develops international best practice and promotes lifelong learning. Most of this evidence has been captured though surveys to returned international volunteers. Read More

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http://dx.doi.org/10.1186/s12992-019-0473-yDOI Listing

Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).

Trials 2019 Apr 23;20(1):230. Epub 2019 Apr 23.

Guy's and St. Thomas' NHS Foundation Trust, London, UK.

Background: MACRO (Defining best Management for Adults with Chronic RhinOsinusitis) is an NIHR-funded programme of work designed to establish best practice for adults with chronic rhinosinusitis (CRS). The 7-year programme comprises three consecutive workstreams, designed to explore NHS care pathways through analysis of primary and secondary data sources, and to undertake a randomised controlled trial to evaluate a longer-term course of macrolide antibiotics and endoscopic sinus surgery for patients with CRS. A number of outstanding elements still required clarification at the funding stage. Read More

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http://dx.doi.org/10.1186/s13063-019-3318-3DOI Listing

Stress Management Interventions for Nurses: Critical Literature Review.

J Holist Nurs 2019 Apr 23:898010119842693. Epub 2019 Apr 23.

Mayo Clinic.

Background: The nursing literature contains numerous studies on stress management interventions for nurses, but their overall levels of evidence remain unclear. Holistic nurses use best-available evidence to guide practice with self-care interventions. Ongoing discovery of knowledge, dissemination of research findings, and evidence-based practice are the foundation of specialized practice in holistic nursing. Read More

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http://dx.doi.org/10.1177/0898010119842693DOI Listing

Integrated Care for People with Dementia-Results of a Social-Scientific Evaluation of an Established Dementia Care Model.

Authors:
Stefanie Richter

Geriatrics (Basel) 2016 Dec 27;2(1). Epub 2016 Dec 27.

Department II: Social Infrastructure and Health, Wilhelm Löhe University of Applied Sciences (WLH), Merkurstrasse 41, D-90763 Fürth, Bavaria, Germany.

Currently, approximately 46.8 million people worldwide and 1.47 million German people are affected by dementia. Read More

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http://dx.doi.org/10.3390/geriatrics2010001DOI Listing
December 2016

The Emerging Role of Nurse Practitioners and Physician Assistants in Liver Transplantation.

Liver Transpl 2019 Apr 23. Epub 2019 Apr 23.

Division of Transplant Medicine, Mayo Clinic, Jacksonville, Florida.

The evolution of nurse practitioners (NP) and physician assistants (PA) in the United States continues to progress. NPs and PAs have expanded from primary care practices, to medical and surgical specialties, provide acute care in hospitals and intensive care units, and serve as educators, lobbyists, and researchers. Questions have arisen from NP/PA leaders, physician leaders, and administrators on how to best implement a successful NP/PA model within their practice. Read More

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http://dx.doi.org/10.1002/lt.25474DOI Listing

The BEST criteria improve sensitivity for detecting positive cultures in residual blood components cultured in suspected septic transfusion reactions.

Transfusion 2019 Apr 23. Epub 2019 Apr 23.

Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

Background: Culturing residual blood components after suspected septic transfusion reactions guides management of patients and cocomponents. Current practice, accuracy of provider vital sign assessment, and performance of the AABB culture criteria are unknown. A multicenter international study was undertaken to investigate these issues and develop improved culture criteria. Read More

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http://dx.doi.org/10.1111/trf.15317DOI Listing
April 2019
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Developing a Physical Activity Ontology to Support the Interoperability of Physical Activity Data.

J Med Internet Res 2019 Apr 23;21(4):e12776. Epub 2019 Apr 23.

Department of Radiological Science, University of California Los Angeles, Los Angeles, CA, United States.

Background: Physical activity data provides important information on disease onset, progression, and treatment outcomes. Although analyzing physical activity data in conjunction with other clinical and microbiological data will lead to new insights crucial for improving human health, it has been hampered partly because of the large variations in the way the data are collected and presented.

Objective: The aim of this study was to develop a Physical Activity Ontology (PACO) to support structuring and standardizing heterogeneous descriptions of physical activities. Read More

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http://dx.doi.org/10.2196/12776DOI Listing

Pilot of a Charter to Improve Management of Medicines and Oral Care for Residents with Dysphagia in Care Homes.

Geriatrics (Basel) 2018 Nov 15;3(4). Epub 2018 Nov 15.

School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.

Research in care homes has demonstrated that medication management practices in patients with dysphagia and those receiving medicines covertly may be inappropriate, illegal, and potentially cause harm. This paper presents the results of a feasibility study piloting a resident and healthcare professional best practice charter to improve such practices in care home residents with dysphagia. A charter was developed through a multi-professional expert panel, implemented in one care home, and then piloted in 22 homes in England, Wales, and Northern Ireland. Read More

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http://dx.doi.org/10.3390/geriatrics3040078DOI Listing
November 2018

Dehydration and Malnutrition in Residential Care: Recommendations for Strategies for Improving Practice Derived from a Scoping Review of Existing Policies and Guidelines.

Geriatrics (Basel) 2018 Nov 12;3(4). Epub 2018 Nov 12.

Norwich Medical School, Norwich Research Park, University of East Anglia, Norwich NR4 7TJ, UK.

Preventing malnutrition and dehydration in older care home residents is a complex task, with both conditions remaining prevalent, despite numerous guidelines spanning several decades. This policy-mapping scoping review used snowballing search methods to locate publicly-available policies, reports and best practice guidelines relating to hydration and nutrition in UK residential care homes, to describe the existing knowledge base and pinpoint gaps in practice, interpretation and further investigation. The findings were synthesised narratively to identify solutions. Read More

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http://dx.doi.org/10.3390/geriatrics3040077DOI Listing
November 2018

Orthogeriatrics and Hip Fracture Care in the UK: Factors Driving Change to More Integrated Models of Care.

Authors:
Mark Middleton

Geriatrics (Basel) 2018 Aug 28;3(3). Epub 2018 Aug 28.

Department of Trauma and Orthopaedics, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London SW17 0QT, UK.

In the United Kingdom (UK), approximately 80,000 hip fractures each year result in an estimated annual cost of two billion pounds in direct healthcare costs alone. Various models of care exist for collaboration between orthopaedic surgeons and geriatricians in response to the complex medical, rehabilitation, and social needs of this patient group. Mounting evidence suggests that more integrated models of orthogeriatric care result in superior quality of care indicators and clinical outcomes. Read More

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http://dx.doi.org/10.3390/geriatrics3030055DOI Listing

Reoperative surgery for nonresponders and complicated sleeve gastrectomy operations in patients with severe obesity. An international expert panel consensus statement to define best practice guidelines.

Surg Obes Relat Dis 2019 Feb 15;15(2):173-186. Epub 2018 Nov 15.

Advanced Laparoscopic Surgery Associates, Fresno, California.

Background: Laparoscopic sleeve gastrectomy (SG) has rapidly become the most commonly performed bariatric procedure in the United States as well as other countries, with approximately 120,000 procedures being performed annually in the United States. Reoperative interventions after SG have become more prevalent in the past few years since the initial development of SG as a primary operation. Given the expected rapid growth of these reinterventions, an expert consensus conference was held with some of the most experienced bariatric surgeons in the world to better understand, discuss, and provide consensus on the reasons, indications, contraindications, and surgical options for nonresponders and complicated SG operations. Read More

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http://dx.doi.org/10.1016/j.soard.2018.11.006DOI Listing
February 2019

Comparison of specialties participating in the BEST-CLI trial to specialists treating peripheral arterial disease nationally.

J Vasc Surg 2019 May;69(5):1505-1509

Division of Vascular Surgery, Department of Surgery, New England Deaconess Medical Center, Boston, Mass.

Background: The Best Endovascular vs Best Surgical Therapy for Patients with Critical Limb Ischemia (BEST-CLI) trial compares open surgery and endovascular therapy for the treatment of critical limb ischemia (CLI). This report describes the types and proportion of investigators participating in BEST-CLI and determines how these compare with those specialists treating peripheral artery disease (PAD) outside of the trial.

Methods: To be credentialed to enroll in BEST-CLI, investigators must be approved by the Surgical and Interventional Management Committee to have sufficient experience and skill in the management of patients with CLI. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.08.188DOI Listing

SCIT Versus SLIT: Which One Do You Recommend, Doc?

Am J Med Sci 2019 May 10;357(5):442-447. Epub 2019 Feb 10.

Department of Otolaryngology, Emory University, Atlanta, Georgia.

Allergic rhinitis is a prevalent condition that has a significant impact on the quality of life of many patients. When initial therapy fails to control the symptoms, allergen immunotherapy (AIT) has been suggested as an option by the Joint Task Force on Practice Parameters. The 2 main forms of AIT are via subcutaneous and sublingual routes, called subcutaneous immunotherapy and sublingual immunotherapy, respectively. Read More

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http://dx.doi.org/10.1016/j.amjms.2019.02.004DOI Listing

The Absence of Evidence-Based Practices (EBPs) in the Treatment of Sexual Abusers: Recommendations for Moving Toward the Use of a True EBP Model.

Sex Abuse 2019 Apr 22:1079063219843897. Epub 2019 Apr 22.

2 Liberty Healthcare Corporation, Bala Cynwyd, PA, USA.

Despite a continued evolution of the field of sexual abuser treatment toward a distinct professional discipline with clinicians using an increasing variety of treatment approaches, there is no consensus regarding the strength of our various clinical interventions as evidence-based practices (EBPs). This article provides a brief history of the development and goals of EBPs in medicine and mental health, and a review of the earnest efforts of researchers within the field to establish treatment approaches with sexual abusers as evidence-based. An appraisal of the current status of EBP's with sexual abusers is provided. Read More

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http://dx.doi.org/10.1177/1079063219843897DOI Listing

Interdisciplinary User Groups and the Design of Healthcare Facilities.

Authors:
Jane Carthey

HERD 2019 Apr 22:1937586719843877. Epub 2019 Apr 22.

1 Faculty of Creative Industries, Queensland University of Technology, Brisbane, Queensland, Australia.

Aim: This Australian research explores how "user group" participants from diverse professional discipline backgrounds understand, define, perform their roles, and assess the outcomes of the healthcare design process.

Background: Part of the design process in Australia and New Zealand, the purpose of interdisciplinary user group consultation is to design the best healthcare facilities possible within the parameters set by project clients and funding bodies.

Method: An online survey was used to explore how user group participants viewed the process, including how well informed they felt they were about their role/s in it, its success in achieving specific outcomes for their project, and how they felt their project client, owner, or funding body assessed these same issues. Read More

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http://dx.doi.org/10.1177/1937586719843877DOI Listing

Improving reperfusion time within the ESCAPE Endovascular Clinical Trial.

Eur Stroke J 2017 Mar 30;2(1):64-69. Epub 2016 Nov 30.

Departments of Clinical Neurosciences, Medicine, Radiology and Community Health Sciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Canada.

Introduction: Endovascular treatment of acute ischemic stroke is more effective when performed quickly. In this report, we describe quality interventions to ensure fast endovascular treatment times in the ESCAPE (Endovascular Treatment for Small Core and Anterior circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times) trial.

Methods: An "audit and feedback" intervention using webinar and letter was used to improve treatment time over the course of the trial. Read More

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http://dx.doi.org/10.1177/2396987316681176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453179PMC

"The Safety Dance": A Faculty Development Workshop Partnering IPE and Patient Safety Initiatives Using Simulation-Based Education.

MedEdPORTAL 2016 Aug 26;12:10440. Epub 2016 Aug 26.

Nursing Director, New York Simulation Center for the Health Sciences.

Introduction: Interprofessional collaboration (IPC) is important for improving patient outcomes and patient safety; however, interprofessional education (IPE) is required to develop skills necessary for successful IPC. IPE is resource intensive and requires advance planning and negotiation of logistical challenges. The goal of this faculty development workshop is to train administrators and educators from academic health care institutions to address potential challenges faced during design and implementation of IPE programs. Read More

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http://dx.doi.org/10.15766/mep_2374-8265.10440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464423PMC

Reforming Your Health Care Reform Curriculum.

MedEdPORTAL 2016 Jun 10;12:10413. Epub 2016 Jun 10.

Vice President of Academic Affairs, Memorial Health Care System.

Introduction: The landscape of health care is changing drastically, and the future within which our residents practice medicine will look very different than today's current health care system. Our residency program created a weeklong introduction to health care reform in the United States for residents.

Methods: The materials for faculty facilitators associated with this publication include PowerPoint presentations, a debate script on bundled payments, and an evaluation survey. Read More

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http://dx.doi.org/10.15766/mep_2374-8265.10413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464445PMC

Fate of Mycobacterium avium subsp. paratuberculosis and changes in bacterial diversity populations in dairy slurry after chemical treatments.

J Appl Microbiol 2019 Apr 22. Epub 2019 Apr 22.

Instituto de Medicina Preventiva Veterinaria.

Aims: A major drawback of using dairy slurry as fertilizer is that it may contains pathogens such as Mycobacterium avium subsp. paratuberculosis (MAP), and it could represent a risk to animal and public health. Thus, the aim of this study was to evaluate the fate of MAP and bacterial communities in dairy slurry after chemical treatments. Read More

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http://dx.doi.org/10.1111/jam.14288DOI Listing

Review of Existing Scoring Systems For Massive Blood Transfusion in Trauma Patients: Where Do We Stand?

Shock 2019 Apr 16. Epub 2019 Apr 16.

Department of Surgery, Trauma Surgery, Hamad General Hospital, Doha, Qatar.

Background: Uncontrolled bleeding is the main cause of the potential preventable death in trauma patients. Accordingly, we reviewed all the existing scores for massive transfusion posttraumatic hemorrhage and summarized their characteristics, thus making it easier for the reader to have a global view of these scores - how they were created, their accuracy and to which population they apply.

Methods: A narrative review with a systematic search method to retrieve the journal articles on the predictive scores or models for massive transfusion was carried out. Read More

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http://dx.doi.org/10.1097/SHK.0000000000001359DOI Listing

Professionals' Knowledge, Attitudes, and Practices Related to Pressure Injuries in Canada.

Adv Skin Wound Care 2019 May;32(5):228-233

In Ontario, Canada, Kimberly LeBlanc PhD, RN, WOCC (C), IIWCC, is Chair, Wound Ostomy Continence Institute, Ottawa; Kevin Woo, PhD, RN, NSWOC, FAPWCA, is Associate Professor, Faculty of Health Sciences, Queen's University, Kingston; Katie Bassett, BA, is Communications Specialist, Wounds Canada, North York; Mariam Botros, DPM, is Executive Director, Wounds Canada, and Director, Diabetic Foot Canada, North York.

Background: Pressure injuries (PIs) represent a significant burden on the healthcare system and have a negative impact on the quality of life of those affected by these wounds. Despite best practice guidelines and other protocols to help healthcare facilities prevent PIs, the prevalence of PIs in Canada across all healthcare settings is concerning.

Objective: To describe the pattern of PI prevention and identify national priorities and opportunities to address PIs. Read More

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http://dx.doi.org/10.1097/01.ASW.0000554444.52120.f6DOI Listing
May 2019
1 Read

Patient costs and outcomes before and after the institution of a pre-eclampsia quality improvement initiative in a southwestern tertiary facility.

J Obstet Gynaecol 2019 Apr 22:1-5. Epub 2019 Apr 22.

e Marian Regional Medical Centre , Maternal-Foetal Medicine , Santa Maria , CA , USA.

The study objective was to evaluate the effect of the California Maternal Quality Care Collaborative (CMQCC) initiative, as implemented in a southwestern U.S. tertiary hospital, on associated patient costs and outcomes. Read More

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https://www.tandfonline.com/doi/full/10.1080/01443615.2019.1
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http://dx.doi.org/10.1080/01443615.2019.1575343DOI Listing
April 2019
1 Read

Longitudinal studies of ageing: from insights to impacts: commentary to accompany themed collection on longitudinal studies.

Age Ageing 2019 Apr 22. Epub 2019 Apr 22.

Associate Professor in Medical Gerontology, Trinity College Dublin and Consultant Physician, St James's Hospital, Dublin.

'Time is the best diagnostician': who has not thought this? In clinical practice, presentations are often subtle and decisions made in the face of a 'snapshot.' Crystal balls do not exist; yet, insights from longitudinal studies can help to recognise emerging pictures and anticipate typical trajectories. In the multifactorial, biopsychosocial world of geriatrics, the determinants of those trajectories, and hence opportunities to modify them, can be better understood through careful longitudinal disentangling of the wider determinants of health, and this can be done at multiple levels of analysis, from molecules to society. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afz028DOI Listing
April 2019
1 Read

Association between glycated haemoglobin, glycated albumin and fructosamine with neonatal birthweight and large-for-date status infants in gestational diabetes mellitus: a prospective cohort study.

J Obstet Gynaecol 2019 Apr 22:1-6. Epub 2019 Apr 22.

a Department of Maternal-Fetal Medicine , Central Lisbon Hospital Center , Lisbon , Portugal.

This study aims to investigate associations between glycated haemoglobin (HbA1c), glycated albumin (GA) and fructosamine with neonatal birthweight in gestational diabetes mellitus (GDM). The prospective cohort consisted of 82 women with GDM and their newborns, enrolled between November 2016 and September 2017. Considering neonatal birthweight and birthweights ≥90th percentile for gestational age as outcomes, linear and logistic regression models were used, respectively. Read More

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http://dx.doi.org/10.1080/01443615.2019.1584886DOI Listing
April 2019
1 Read

A Needs Assessment of Family Physicians to Inform Development of Educational Resources on Antipsychotic Use in Dementia.

J Prim Care Community Health 2019 Jan-Dec;10:2150132719840113

1 The University of Iowa, Iowa City, IA, USA.

Objectives: Objectives of this study were to (1) assess the needs and preferred resources of Iowa physicians to inform the development of educational resources for best practice dementia care and (2) compare the responses of nursing home medical directors with nonmedical directors.

Methods: Of 498 physicians, 101 (20%) completed and returned the survey. Family physicians were obtained from a list of family physicians from the Iowa Board of Medical Examiners. Read More

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http://dx.doi.org/10.1177/2150132719840113DOI Listing

The effect of speech training experiences on speechreading skills of Chinese children with hearing impairment.

Clin Linguist Phon 2019 Apr 21:1-15. Epub 2019 Apr 21.

a Department of Special Education , Central China Normal University , Wuhan , China.

Speechreading contributes significantly to effective communication, and persons with hearing impairment (HI) may need to rely more on speechreading. However, whether they may benefit from training/practice to improve their speechreading performance remains unclear. In this study, we examine the effect of speech training on speechreading performance of children with HI in China, and how such effect, if any, may be influenced by age. Read More

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http://dx.doi.org/10.1080/02699206.2019.1604807DOI Listing

Adherence to nutritional supplementation in cystic fibrosis.

J Pediatr Nurs 2019 Apr 18;47:18-22. Epub 2019 Apr 18.

Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA; University of Pennsylvania Perelman School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA 19104, USA.

Purpose: The purpose of this study was to examine patterns of adherence to a novel dietary supplement in pediatric cystic fibrosis. Adherence to dietary supplementation in cystic fibrosis is challenging, and examination of patterns of adherence behavior over time is needed to better characterize subgroups of patients who need self-management support.

Design And Methods: We prospectively examined adherence to Lym-X-Sorb™ (LXS), an organized lipid matrix dietary supplementation for patients with cystic fibrosis (CF) and pancreatic insufficiency (PI), over a 12-month period. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08825963183057
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http://dx.doi.org/10.1016/j.pedn.2019.04.011DOI Listing
April 2019
1 Read

Untangling the ethical intersection of epidemiology, human subjects research, and public health.

Ann Epidemiol 2019 Mar 27. Epub 2019 Mar 27.

Division of Epidemiology and Population Sciences, Department of Public Health Sciences, University of Miami, Miami, FL.

Purpose: Members of the American College of Epidemiology (ACE) Ethics Committee identified current ethics and epidemiology topic areas to consider for further discussion, consultation, teaching opportunities, and conference presentation. This article reflects on the activities of the Committee at the ACE Annual Meeting in New Orleans, Louisiana, September 24-26, 2017.

Methods: The overall aim for the Ethics Committee was to engage members of the College and other audiences and highlight the evolution of ethics and epidemiology since the inception of the original Ethics Guidelines published by the ACE Ethics and Standards of Practice Committee in 2000. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10472797183095
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http://dx.doi.org/10.1016/j.annepidem.2019.03.009DOI Listing
March 2019
1 Read

Clinical practice patterns in laryngeal cancer and introduction of CT lung screening.

Am J Otolaryngol 2019 Apr 12. Epub 2019 Apr 12.

Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States of America. Electronic address:

Objectives: After the publication of large clinical trials, in January 2014 The U.S. Preventive Services Task Force (USPSTF) recommended annual lung cancer screening with low-dose CT in a well-defined group of high-risk smokers. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.04.010DOI Listing

How should end-of-life advance care planning discussions be conducted according to patients and informal carers? A qualitative review of reviews.

J Pain Symptom Manage 2019 Apr 17. Epub 2019 Apr 17.

Division of Nursing, Midwifery & Social Work, School of Health Sciences, University of Manchester, Oxford Road, Manchester M13 9PL; National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care (NIHR CLAHRC) Greater Manchester.

Context: The goal of advance care planning (ACP) is to help ensure that the care people receive during periods of serious illness is consistent with their preferences and values. There is a lack of clear understanding about how patients and their informal carers feel ACP discussions should be conducted.

Objectives: To synthesise literature reviews pertaining to patients' and informal carers' perspectives on ACP discussions. Read More

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http://dx.doi.org/10.1016/j.jpainsymman.2019.04.013DOI Listing

Come Dance With Me: Transformative Changes in the Science and Practice of Drug-Drug Interactions.

Clin Pharmacol Ther 2019 Apr 20. Epub 2019 Apr 20.

Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK.

The past 2 decades have witnessed transformative changes in our approach to drug-drug interactions (DDIs) from scientific research to clinical practice. Collaborative cooperation across the sectors of academia, pharmaceutical industry, providers of translational research tools and services, global regulatory agencies, and healthcare providers has created and galvanized a science-informed and patient-centered approach. Multidisciplinary innovations in mechanistic assessment of absorption, distribution, metabolism, and excretion (ADME), population pharmacology and pharmacogenetics, physiologically based modeling, and regulatory science have enabled a profound shift in mindset from risk aversion to informative prescribing guidance for optimal risk management. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1433
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http://dx.doi.org/10.1002/cpt.1433DOI Listing
April 2019
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Variation in hospital charges in patients with external ventricular drains: comparison between the intensive care and surgical floor settings.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

3Department of Neurosurgery, University of Washington School of Medicine, Seattle, Washington.

OBJECTIVEPlacement of an external ventricular drain (EVD) is a common and potentially life-saving neurosurgical procedure, but the economic aspect of EVD management and the relationship to medical expenditure remain poorly studied. Similarly, interinstitutional practice patterns vary significantly. Whereas some institutions require that patients with EVDs be monitored strictly within the intensive care unit (ICU), other institutions opt primarily for management of EVDs on the surgical floor. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/aop/art
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http://dx.doi.org/10.3171/2019.2.PEDS18545DOI Listing
April 2019
2 Reads

Indigenous Doulas: A literature review exploring their role and practice in western maternity care.

Midwifery 2019 Apr 16;75:52-58. Epub 2019 Apr 16.

Charles Darwin University, Australia.

Objective: The purpose of this article is to establish a body of literature exploring the emergent topic of Indigenous doulas, in relation to Indigenous communities in remote locations, where women are routinely evacuated and no longer supported to give birth. In doing so the article will synthesise and critique key concepts in the literature and identify gaps for prioritisation in future research.

Design: The methodology is influenced by Indigenous, decolonising and feminist theoretical standpoints. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02666138193008
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http://dx.doi.org/10.1016/j.midw.2019.04.005DOI Listing
April 2019
2 Reads

International Board Certified Lactation Consultants' Practices Regarding Supplemental Feeding Methods for Breastfed Infants.

J Hum Lact 2019 Apr 19:890334419835744. Epub 2019 Apr 19.

5 University of Texas Health Science Center San Antonio, School of Nursing, San Antonio, TX, USA.

Background: According to the Baby Friendly Hospital Initiative, when supplementary feeding occurs, mothers should be counseled on the use and risks of feeding bottles and teats. To help support this initiative it is important to understand the supplementation practices of Internationally Board Certified Lactation Consultants (IBCLC)®.

Research Aims: To determine (1) if the location of an IBCLC's practice has any impact on supplemental feeding methods; (2) the preferred methods of and the main reasons for supplementation; (3) the level of an IBCLC's confidence with supplemental feeding methods; (4) who is making supplemental feeding decisions; and (5) if there are geographical differences among supplementation choices and reasons for supplementation. Read More

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http://dx.doi.org/10.1177/0890334419835744DOI Listing

LIDAR explains diversity of plants, fungi, lichens and bryophytes across multiple habitats and large geographic extent.

Ecol Appl 2019 Apr 19:e01907. Epub 2019 Apr 19.

Section for Ecoinformatics and Biodiversity, Department of Bioscience, Aarhus University, Ny Munkegade 114, DK, 8000, Aarhus C, Denmark.

Effective planning and nature management require spatially accurate and comprehensive measures of the factors important for biodiversity. LIDAR (Light detection and ranging) can provide exactly this, and is therefore a promising technology to support future nature management and related applications. However, until now studies evaluating the potential of LIDAR for this field have been highly limited in scope. Read More

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http://dx.doi.org/10.1002/eap.1907DOI Listing

The best perinatal depression screening: Is self-administered PHQ2 more feasible than a nurse-administered one?

Perspect Psychiatr Care 2019 Apr 18. Epub 2019 Apr 18.

Department of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York.

Purpose: To assess perinatal depression screening via self-administered PHQ2 (SAP) vs nurse-administered PHQ2 (NAP).

Design And Methods: NAP screening was performed for 3 months, followed by SAP. Data were gathered from visits at 24 to 28 weeks gestation. Read More

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http://dx.doi.org/10.1111/ppc.12383DOI Listing

Evaluation of giant cell tumors by diffusion weighted imaging-fractional ADC analysis.

Skeletal Radiol 2019 Apr 19. Epub 2019 Apr 19.

Department of Radiology, Musculoskeletal Imaging, UT Southwestern Medical Center, 5323 Harry Hines Blvd, E230-C, Dallas, TX, 75390-9316, USA.

Background: A single ADC value is used in clinical practice on multi b-value acquisitions. Low b-value acquisitions are affected by intravoxel incoherent motion, which is dependent on perfusion. Giant cell tumors (GCTs) are known to exhibit early arterial enhancement and low ADC values. Read More

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http://dx.doi.org/10.1007/s00256-019-03219-8DOI Listing

Service-Learning as a Practical Introduction to Undergraduate Public Health: Benefits for Student Outcomes and Accreditation.

Front Public Health 2019 2;7:63. Epub 2019 Apr 2.

The Center for Community Work and Learning, St. Catherine University, St. Paul, MN, United States.

Since the mid-1980s, service-learning has gained recognition as a pedagogical model in higher education with exciting potential for students' academic, civic, and professional development (1). Deemed a high-impact educational practice by the American Association of Colleges and Universities (AAC&U), extant research points to student learning, engagement, and retention benefits from community-based experiences integrated into curriculum (2, 3). Numerous studies have examined best practices for service-learning from varying stakeholder perspectives (faculty, student, and community partner) and disciplines, however, due to the recent development of public health as a major offering in U. Read More

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https://www.frontiersin.org/article/10.3389/fpubh.2019.00063
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http://dx.doi.org/10.3389/fpubh.2019.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454065PMC
April 2019
1 Read

Neonatal Chylothoraces: A 10-Year Experience in a Tertiary Neonatal Referral Centre.

Case Rep Pediatr 2019 13;2019:3903598. Epub 2019 Mar 13.

Neonatal Intensive Care Centre, Kings College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.

Background: Neonatal chylothorax is a rare condition, but has a high mortality.

Study Objectives: To analyse the outcomes of a series of neonates with chylothorax and review the literature to determine best practice.

Design: A case series review and a literature review using electronic databases including the key words neonates and chylothorax. Read More

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https://www.hindawi.com/journals/cripe/2019/3903598/
Publisher Site
http://dx.doi.org/10.1155/2019/3903598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436362PMC
March 2019
1 Read

The use of chemotherapeutic agents as prophylaxis for recurrent urinary tract infection in healthy nonpregnant women: A network meta-analysis.

Indian J Urol 2019 Apr-Jun;35(2):147-155

Department of Obstetrics and Gynaecology, International Medical University Clinical Campus Seremban, Negeri Sembilan, Malaysia.

Introduction: The aim of this systematic review is to compare chemotherapeutic agents commonly used in treating recurrent urinary infection in nonpregnant women by their efficacy, tolerability, adverse effects, and cost employing network meta-analysis.

Materials And Methods: We used three online databases, i.e. Read More

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http://dx.doi.org/10.4103/iju.IJU_378_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458811PMC
April 2019
2 Reads

Protocol-based perioperative antimicrobial prophylaxis in urologic surgeries: Feasibility and lessons learned.

Indian J Urol 2019 Apr-Jun;35(2):141-146

Department of Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Rational use of antibiotics and strict adherence to practice guidelines is essential to prevent antibiotic resistance. The best surgical prophylaxis protocol requires tailoring of the available guidelines in accordance to the local bacterial flora. We designed a protocol for surgical prophylaxis to check the rampant abuse of antibiotics in the department of urology and evaluated its feasibility. Read More

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http://dx.doi.org/10.4103/iju.IJU_270_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458815PMC