161,175 results match your criteria Best Practice & Research: Clinical Gastroenterology[Journal]


Duration of untreated illness and response to SRI treatment in Obsessive-Compulsive Disorder.

Eur Psychiatry 2019 Feb 11;58:19-26. Epub 2019 Feb 11.

Rita Levi Montalcini Department of Neuroscience, University of Turin, Italy and San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.

Background: The duration of untreated illness (DUI) is a potentially modifiable parameter associated with worst prognosis in several psychiatric disorders, but poorly investigated in Obsessive-Compulsive Disorder (OCD). Our aims were to estimate the mean DUI in a large sample of individuals with OCD and its impact on response to the first ever adequate SRI treatment.

Methods: We retrospectively examined records of 251 patients with OCD (SCID-I, DSM-IV) who referred to our Department and were prospectively and naturalistically treated according to International Guidelines. Read More

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http://dx.doi.org/10.1016/j.eurpsy.2019.01.017DOI Listing
February 2019

The optimal use of imaging in Radiation Therapy for lymphoma - Guidelines from the International Lymphoma Radiation Oncology Group (ILROG).

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Radiation therapy (RT) for the management of lymphomas has evolved over the past decades. Large extended or involved fields have been replaced by smaller involved site or nodal volumes. Currently, customized plans are created for each individual patient that encompass only the areas involved by disease. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.001DOI Listing
February 2019

Cardiac Function After Radiotherapy for Breast Cancer.

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30, 001, 9700 RB Groningen, The Netherlands. Electronic address:

Purpose: The main purpose of this study was to test the hypothesis that incidental cardiac irradiation is associated with changes in cardiac function in breast cancer (BC) survivors treated with radiotherapy (RT).

Methods And Materials: We conducted a cross-sectional study consisting of 109 BC survivors treated with RT between 2005 and 2011. The endpoint was cardiac function, assessed by echocardiography. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.003DOI Listing
February 2019

Introduction to a new Special Series for the Journal of Pain and Symptom Management - Science in Action: Evidence and opportunities for palliative care across diverse populations and care settings.

J Pain Symptom Manage 2019 Feb 11. Epub 2019 Feb 11.

Director of Quality and Research, American Academy of Hospice and Palliative Medicine (AAHPM), Chicago, IL.

Practices to optimize palliative care delivery and new opportunities in which to integrate palliative care vary across populations and care settings. Systematic reviews are an efficient and methodologically rigorous approach to summarize existing research to identify both evidence-based best-practices as well as new areas for future research and clinical practice. This is the introduction to a special series of articles in which members of the AAHPM Research Committee report the results of circumscribed systematic reviews which in a specific population or care setting seek to: (a) summarize existing evidence for optimal palliative care practices or (b) identify opportunities where better palliative care delivery could improve patient and/or family outcomes. Read More

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http://dx.doi.org/10.1016/j.jpainsymman.2019.02.005DOI Listing
February 2019

A comparison of patients managed in specialist versus non-specialist inpatient rehabilitation units in Australia.

Disabil Rehabil 2019 Feb 14:1-8. Epub 2019 Feb 14.

c Australasian Rehabilitation Outcomes Centre , Wollongong , Australia.

Aim: To compare the rehabilitation of patients with brain and spinal cord injury in specialist rehabilitation units and non-specialist rehabilitation units in Australia over a 10-year period.

Method: A retrospective cohort study design was used. Epidemiological descriptive analysis was used to examine inpatient rehabilitation data held in the Australasian Rehabilitation Outcomes Centre Registry Database at four discrete time points: 2007, 2010, 2013 and 2016. Read More

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http://dx.doi.org/10.1080/09638288.2019.1568592DOI Listing
February 2019

Hypertensive ocular disease in cats: A guide to fundic lesions to facilitate early diagnosis.

Authors:
Jenny Carter

J Feline Med Surg 2019 Jan;21(1):35-45

Auckland, New Zealand.

Practical Relevance:: Systemic hypertension is common in older cats and can result in damage to organs with a rich arteriolar supply such as the eyes, kidneys, myocardium and brain. Hypertensive disease in these organs is known as target organ damage (TOD). Disease in the eye resulting from hypertension is the most easily identifiable form of TOD and can often be the reason the cat is presented to the veterinarian. Read More

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http://dx.doi.org/10.1177/1098612X18818668DOI Listing
January 2019

Determining Best Practices for Management of Bacteriuria in Spinal Cord Injury: Protocol for a Mixed-Methods Study.

JMIR Res Protoc 2019 Feb 14;8(2):e12272. Epub 2019 Feb 14.

Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, United States.

Background: Bacteriuria, either asymptomatic (ASB) or symptomatic, urinary tract infection (UTI), is common in persons with spinal cord injury (SCI). Current Veterans Health Administration (VHA) guidelines recommend a screening urinalysis and urine culture for every veteran with SCI during annual evaluation, even when asymptomatic, which is contrary to other national guidelines. Our preliminary data suggest that a positive urine culture (even without signs or symptoms of infection) drives antibiotic use. Read More

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https://www.researchprotocols.org/2019/2/e12272/
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http://dx.doi.org/10.2196/12272DOI Listing
February 2019
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Yvonne M. Agazarian (1929-2017).

Authors:
Susan P Gantt

Am Psychol 2019 Feb-Mar;74(2):259

Emory University School of Medicine.

Presents an obituary for Yvonne M. Agazarian (1929-2017). Agazarian was a brilliant theoretician, clinician, and teacher who devoted her life to the development of a theory of living human systems (TLHS) and its systems-centered therapy and training (SCT). Read More

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http://dx.doi.org/10.1037/amp0000332DOI Listing
February 2019

Use of a combination strategy to improve neuroprotection and neuroregeneration in a rat model of acute spinal cord injury.

Neural Regen Res 2019 Jun;14(6):1060-1068

Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México Campus Norte, Huixquilucan, Edo. de México, México; Centro de Investigación del Proyecto CAMINA A.C.; Ciudad de México, México.

Spinal cord injury is a very common pathological event that has devastating functional consequences in patients. In recent years, several research groups are trying to find an effective therapy that could be applied in clinical practice. In this study, we analyzed the combination of different strategies as a potential therapy for spinal cord injury. Read More

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http://dx.doi.org/10.4103/1673-5374.250627DOI Listing

Patient stakeholder engagement in research: A narrative review to describe foundational principles and best practice activities.

Health Expect 2019 Feb 13. Epub 2019 Feb 13.

Division of Hospital Medicine, University of California San Francisco, San Francisco, California.

Background: Health research is evolving to include patient stakeholders (patients, families and caregivers) as active members of research teams. Frameworks describing the conceptual foundations underlying this engagement and strategies detailing best practice activities to facilitate engagement have been published to guide these efforts.

Objective: The aims of this narrative review are to identify, quantify and summarize (a) the conceptual foundational principles of patient stakeholder engagement in research and (b) best practice activities to support these efforts. Read More

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http://dx.doi.org/10.1111/hex.12873DOI Listing
February 2019

Point-Of-Care Testing Curriculum and Accreditation for Public Health-Enabling Preparedness, Response, and Higher Standards of Care at Points of Need.

Front Public Health 2018 29;6:385. Epub 2019 Jan 29.

Point-of-Care Testing Center for Teaching and Research, Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.

To develop awareness of benefits of point-of-care testing (POCT) education in schools of public health, to identify learning objectives for teaching POCT, to enable public health professionals and emergency responders to perform evidence-based diagnosis and triage effectively and efficiently at points of need, and to better improve future standards of care for public health practice, including in limited-resource settings and crisis situations. We surveyed all U.S. Read More

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http://dx.doi.org/10.3389/fpubh.2018.00385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361824PMC
January 2019

Concordance Among Bioelectrical Impedance Analysis Measures of Percent Body Fat in Athletic Young Adults.

Int J Exerc Sci 2019 1;12(4):324-331. Epub 2019 Jan 1.

Health and Exercise Science Department, Lenoir-Rhyne University, Hickory, NC, USA.

The purpose of this investigation was to determine the agreement among three bioelectrical impedance analysis devices (BIA) in athletic young adults. Fifty-one participants (26 men and 25 women) were assessed for percent body fat (PBF) using an arm-to-arm bipolar single-frequency device (ABIA), a leg-to-leg single-frequency device (LBIA), and an octopolar multi-frequency BIA device (MFBIA). PBF was measured with the three devices in a randomized, counterbalanced order. Read More

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January 2019

Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study.

Front Pharmacol 2019 29;10:31. Epub 2019 Jan 29.

National Institutes for Food and Drug Control, Beijing, China.

Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success rates of new drug development, we need to have a comprehensive understanding about the relationship between the structure of cephalosporins and the toxicity that it induces at an early stage. Read More

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http://dx.doi.org/10.3389/fphar.2019.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361752PMC
January 2019

Embracing Cultural Diversity: Meaningful Engagement for Older Adults With Advanced Dementia in a Residential Care Setting.

Am J Occup Ther 2018 Nov/Dec;72(6):7206205090p1-7206205090p8

Helen Buchanan, BSc(OT), MSc(OT), PhD, is Associate Professor, Department of Health and Rehabilitation Sciences, Division of Occupational Therapy, University of Cape Town, Cape Town, South Africa;

Providing person-centered care (PCC) that focuses on meaningful engagement in residential care settings for older adults with moderate to advanced dementia is an internationally recognized challenge. In this study, we aimed to identify best-practice scenarios for supporting older adults with moderate to advanced dementia from culturally and linguistically diverse backgrounds who lived in care facilities. A mixed-methods study with a concurrent triangulation strategy was adopted. Read More

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http://dx.doi.org/10.5014/ajot.2018.027292DOI Listing
February 2019

Incidental finding of Zinner syndrome in a Greek military recruit: a case report of a rare clinical entity.

Mil Med Res 2019 Feb 14;6(1). Epub 2019 Feb 14.

Department of Urology, 424 General Military Hospital of Thessaloniki, 56429, Thessaloniki, Greece.

Background: Zinner syndrome represents a rare congenital malformation of the urinary tract. It comprises a constellation of Wolffian duct anomalies and is almost exclusively encountered as a classic triad of seminal vesicle cysts, ejaculatory duct obstruction and renal agenesis. Patients can be either asymptomatic or symptomatic. Read More

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http://dx.doi.org/10.1186/s40779-019-0194-9DOI Listing
February 2019

Enhanced Auditory Steady-State Response Using an Optimized Chirp Stimulus-Evoked Paradigm.

Sensors (Basel) 2019 Feb 12;19(3). Epub 2019 Feb 12.

Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.

: It has been reported recently that gamma measures of the electroencephalogram (EEG) might provide information about the candidate biomarker of mental diseases like schizophrenia, Alzheimer's disease, affective disorder and so on, but as we know it is a difficult issue to induce visual and tactile evoked responses at high frequencies. Although a high-frequency response evoked by auditory senses is achievable, the quality of the recording response is not ideal, such as relatively low signal-to-noise ratio (SNR). Recently, auditory steady-state responses (ASSRs) play an essential role in the field of basic auditory studies and clinical uses. Read More

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http://www.mdpi.com/1424-8220/19/3/748
Publisher Site
http://dx.doi.org/10.3390/s19030748DOI Listing
February 2019
4 Reads

[Vaccination in Germany - Recommendations of STIKO].

Authors:
Thomas Mertens

Dtsch Med Wochenschr 2019 Feb 13;144(4):239-243. Epub 2019 Feb 13.

The epidemiological effect of vaccination is that it primarily reduces the incidence and prevalence of infectious agents and diseases, providing ideal conditions (also from an economic point of view) for prevention. Goal of vaccination is first the individual protection. Other goals may be "herd immunity", regional repression and global extinction. Read More

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http://dx.doi.org/10.1055/a-0479-3890DOI Listing
February 2019

elPrep 4: A multithreaded framework for sequence analysis.

PLoS One 2019 13;14(2):e0209523. Epub 2019 Feb 13.

ExaScience Life Lab, IMEC, Leuven, Belgium.

We present elPrep 4, a reimplementation from scratch of the elPrep framework for processing sequence alignment map files in the Go programming language. elPrep 4 includes multiple new features allowing us to process all of the preparation steps defined by the GATK Best Practice pipelines for variant calling. This includes new and improved functionality for sorting, (optical) duplicate marking, base quality score recalibration, BED and VCF parsing, and various filtering options. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209523PLOS
February 2019

Radcliffe ARFID Workgroup: Toward operationalization of research diagnostic criteria and directions for the field.

Int J Eat Disord 2019 Feb 13. Epub 2019 Feb 13.

Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.

Objective: Since its introduction to the psychiatric nomenclature in 2013, research on avoidant/restrictive food intake disorder (ARFID) has proliferated highlighting lack of clarity in how ARFID is defined.

Method: In September 2018, a small multi-disciplinary pool of international experts in feeding disorder and eating disorder clinical practice and research convened as the Radcliffe ARFID workgroup to consider operationalization of DSM-5 ARFID diagnostic criteria to guide research in this disorder.

Results: By consensus of the Radcliffe ARFID workgroup, ARFID eating is characterized by food avoidance and/or restriction, involving limited volume and/or variety associated with one or more of the following: weight loss or faltering growth (e. Read More

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http://dx.doi.org/10.1002/eat.23042DOI Listing
February 2019
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The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm.

Diabetes Ther 2019 Feb 13. Epub 2019 Feb 13.

Diabetes Research Centre, University of Leicester, Leicester, UK.

There is currently a worldwide epidemic of type 2 diabetes (T2D) that is predicted to increase substantially in the next few years. With 80% of the global T2D population living in low to middle-income countries, there are issues with cost and of access to appropriate medicines. The objective of this symposium was to provide an overview of the efficacy and safety of glucose-lowering drugs, focussing in particular on sulfonylureas (SUs) in patients with T2D using data taken from both randomised controlled trials (RCTs) and real-world studies, the application of strategies to ensure optimal patient adherence and clinical outcomes, and the optimal use of SUs in terms of dose adjustment and agent choice to ensure the best clinical outcome. Read More

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http://dx.doi.org/10.1007/s13300-019-0573-yDOI Listing
February 2019

Acoustic Voice Quality Index - AVQI for brazilian portuguese speakers: analysis of different speech material.

Codas 2019 Feb 11;31(1):e20180082. Epub 2019 Feb 11.

Universidade Federal de São Paulo - Unifesp - São Paulo (SP), Brasil.

Purpose: This study aimed to verify the best speech material for the AVQI for Brazilian Portuguese language and identify the best validity results between the auditory perceptual judgment (APJ) and the AVQI score on different speech materials.

Methods: We recorded voice samples of 50 individuals (dysphonic and vocally healthy) of several continuous speech (cs) variants (i.e. Read More

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http://dx.doi.org/10.1590/2317-1782/20182018082DOI Listing
February 2019
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Measurement properties of instruments to assess mental function during activity and participation in individuals surviving traumatic brain injury: A systematic review protocol.

Scand J Occup Ther 2019 Feb 13:1-5. Epub 2019 Feb 13.

a Department of Physiotherapy and Occupational Therapy , Aarhus University Hospital , Aarhus , Denmark.

Background: Most studies assessing mental function in individuals with traumatic brain injury (TBI) assess the impairments through pen and paper tests. However, weak correlation has been found between the results from pen and paper tests and the results from performance-based tests during activity and participation.

Objective: To investigate measurement properties of performance-based instruments that are used to assess mental function during activity and participation in individuals with a TBI. Read More

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http://dx.doi.org/10.1080/11038128.2018.1563630DOI Listing
February 2019

Bilateral maxillary augmentation using CAD/CAM manufactured allogenic bone blocks for restoration of congenitally missing teeth: A case report.

J Esthet Restor Dent 2019 Feb 12. Epub 2019 Feb 12.

Private Practice, Munich, Bavaria, Germany.

Objective: Various biomaterials have been successfully applied in alveolar bone regeneration, however, the reconstruction of extensive osseous defects remains challenging and is often unfeasible with granular grafting materials. Several studies have outlined allogenic bone blocks as valid alternative to autologous block grafting.

Clinical Considerations: In this report, we demonstrate the regeneration of two large osseous defects in the maxilla with allogenic bone blocks made from human donor bone. Read More

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http://dx.doi.org/10.1111/jerd.12454DOI Listing
February 2019

Thromboprophylaxis for varicose vein procedures - A national survey.

Phlebology 2019 Feb 12:268355519828931. Epub 2019 Feb 12.

Department of Vascular Surgery, Royal Victoria Hospital, Belfast, UK.

Background: Venous thromboembolism is rare following varicose vein ablation procedures, but uncertainty about its incidence combined with a lack of evidence-based clinical guidelines regarding thromboprophylaxis has led to debate about best practice. We conducted a national survey to investigate current practice among Irish vascular surgeons.

Methods: An anonymous online questionnaire was emailed to all members of the Irish Association of Vascular Surgeons and the Northern Ireland Vascular Society. Read More

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http://dx.doi.org/10.1177/0268355519828931DOI Listing
February 2019

How Best to Establish a Dental Practice.

Authors:
E G Wheeler

Am J Dent Sci 1877 Jan;10(9):400-407

Mobile, Ala.

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January 1877

Best practice for the management of pediatric thyroid cancer.

Expert Rev Endocrinol Metab 2014 Mar 9;9(2):175-182. Epub 2014 Jan 9.

a Endocrine Surgery Unit, University of Sydney, NSW, Australia.

The presentation of differentiated thyroid cancer in children often includes dissemination to lymph nodes. Despite this, the long-term prognosis is excellent with appropriate treatment. A few known hereditary syndromes are associated with paediatric thyroid cancer, although most tumours are sporadic. Read More

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http://dx.doi.org/10.1586/17446651.2014.877342DOI Listing

A review of exhaled breath key role in lung cancer diagnosis.

J Breath Res 2019 Feb 12. Epub 2019 Feb 12.

Department of Bio-Engineering, Politecnico di Milano, Pizza L Da Vinci ,32, 20133 Milano, Milan, ITALY.

One of the main causes of the high mortality rate in lung cancer is the late-stage tumor detection. Early diagnosis is therefore essential to increase the chances of obtaining an effective treatment quickly thus increasing the survival rate. Current screening techniques are based on imaging, with low dose computed tomography (LDCT) as the pivotal approach. Read More

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http://dx.doi.org/10.1088/1752-7163/ab0684DOI Listing
February 2019

Facilitators and barriers to brokering between research and care by senior clinical-scientists in general practice and elderly care medicine.

Educ Prim Care 2019 Feb 12:1-8. Epub 2019 Feb 12.

a Julius Centre , University Medical Centre Utrecht, Utrecht University , Utrecht , The Netherlands.

Background: Clinician-scientists (CSs) are physicians who work in daily care and have an academic role in research or education. They may act as knowledge brokers and help to connect research and clinical practice. There is no data available on CSs' brokering activities and the perceived barriers and facilitators to optimising their role in general practice (GP) and elderly care medicine (EM). Read More

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http://dx.doi.org/10.1080/14739879.2019.1570349DOI Listing
February 2019

Fossils with Feathers and Philosophy of Science.

Syst Biol 2019 Feb 11. Epub 2019 Feb 11.

Campbell Geology Museum, Clemson University, Clemson, SC.

The last half century of paleornithological research has transformed the way that biologists perceive the evolutionary history of birds. This transformation has been driven, since 1969, by a series of exciting fossil discoveries combined with intense scientific debate over how best to interpret these discoveries. Ideally, as evidence accrues and results accumulate, interpretive scientific agreement forms. Read More

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http://dx.doi.org/10.1093/sysbio/syz010DOI Listing
February 2019
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Risk-Informed Intervention: Using Intimate Partner Violence Risk Assessment within an Evidence-Based Practice Framework.

Soc Work 2019 Feb 7. Epub 2019 Feb 7.

Jill Theresa Messing, PhD, MSW, is associate professor, School of Social Work, Arizona State University, 411 N Central Avenue, Suite 800, Phoenix, AZ 85004; e-mail:

Intimate partner violence (IPV) is a pervasive problem in the United States. IPV is often repetitive and may escalate; in a small number of cases, IPV leads to homicide. This article presents an evidence-based practice (EBP) model for risk-informed social work intervention with survivors and perpetrators of IPV. Read More

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http://dx.doi.org/10.1093/sw/swz009DOI Listing
February 2019

Variability in training, practice, and prioritization of services among emergency medicine pharmacists.

Am J Health Syst Pharm 2019 Feb;76(Supplement_1):S21-S27

University of Kentucky HealthCare Pharmacy Services, Lexington, KY.

Purpose: The purpose of this survey-based research project is to identify factors, including prior training, institution demographics, and pharmacist prioritization of services that may impact variability in practice among emergency medicine (EM) pharmacists.

Methods: An electronic survey was available for 6 weeks. Participants were contacted through professional membership directories. Read More

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http://dx.doi.org/10.1093/ajhp/zxy049DOI Listing
February 2019

Financial risk protection at the bedside: How Ethiopian physicians try to minimize out-of-pocket health expenditures.

PLoS One 2019 12;14(2):e0212129. Epub 2019 Feb 12.

Department of Bioethics, National Institutes of Health, Bethesda, Maryland, United States of America.

Background: Out-of-pocket health expenditures can pose major financial risks, create access-barriers and drive patients and families into poverty. Little is known about physicians' role in financial protection of patients and families at the bedside in low-income settings and how they perceive their roles and duties when treating patients in a health care system requiring high out-of-pocket costs.

Objective: Assess physicians' concerns regarding financial welfare of patients and their families and analyze physicians' experiences in reducing catastrophic health expenditures for patients in Ethiopia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212129PLOS
February 2019

Community-based father education intervention on breastfeeding practice-Results of a quasi-experimental study.

Matern Child Nutr 2019 Jan;15 Suppl 1:e12705

Hanoi University of Public Health, Hanoi, Vietnam.

Although the benefits of breastfeeding are well-documented, little is known about how best to encourage fathers to support breastfeeding. A quasi-experimental study of a community-based intervention was designed to examine whether health education to promote fathers' involvement in supporting women is associated with early initiation and exclusive breastfeeding practices. At baseline, 802 couples of fathers with pregnant wives from 12 to 27 weeks of gestational age were recruited to either the intervention group (n = 390) or a control group (n = 412) consisting of couples seeking care through routine maternal and child health services. Read More

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http://dx.doi.org/10.1111/mcn.12705DOI Listing
January 2019

Demonstrating advanced practice provider value: Implementing a new advanced practice provider billing algorithm.

J Am Assoc Nurse Pract 2019 Feb;31(2):93-103

Medical University of South Carolina, Charleston, South Carolina.

Background: Rapid changes in health care are driving the adjustment of work flow by which providers serve patients in team-based care. Specifically, there is a need to develop more effective and efficient utilization with accurate attribution of advanced practice providers' (APPs) productivity.

Local Problem: The Directors of the APP-Best Practice Center conducted assessments of each clinical area at MUSC Health, a large academic medical center. Read More

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http://dx.doi.org/10.1097/JXX.0000000000000155DOI Listing
February 2019

Transforming Mental Health Delivery Through Behavioral Economics and Implementation Science: Protocol for Three Exploratory Projects.

JMIR Res Protoc 2019 Feb 12;8(2):e12121. Epub 2019 Feb 12.

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Background: Efficacious psychiatric treatments are not consistently deployed in community practice, and clinical outcomes are attenuated compared with those achieved in clinical trials. A major focus for mental health services research is to develop effective and cost-effective strategies that increase the use of evidence-based assessment, prevention, and treatment approaches in community settings.

Objective: The goal of this program of research is to apply insights from behavioral economics and participatory design to advance the science and practice of implementing evidence-based practice (EBP) for individuals with psychiatric disorders across the life span. Read More

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http://www.researchprotocols.org/2019/2/e12121/
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http://dx.doi.org/10.2196/12121DOI Listing
February 2019
1 Read

Evaluation of Self-Management Support Functions in Apps for People With Persistent Pain: Systematic Review.

JMIR Mhealth Uhealth 2019 Feb 12;7(2):e13080. Epub 2019 Feb 12.

Department of Medicine, University of Otago, Wellington, New Zealand.

Background: Smartphone apps are a potential mechanism for development of self-management skills in people with persistent pain. However, the inclusion of best-practice content items in available pain management apps fostering core self-management skills for self-management support is not known.

Objective: The aim of the study was to evaluate the contents of smartphone apps providing information on pain management strategies for people with persistent pain facilitating self-management support and to appraise the app quality. Read More

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http://mhealth.jmir.org/2019/2/e13080/
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http://dx.doi.org/10.2196/13080DOI Listing
February 2019
2 Reads

Contributory factors and potentially avoidable neonatal encephalopathy associated with acute peripartum events: An observational study.

Aust N Z J Obstet Gynaecol 2019 Feb 12. Epub 2019 Feb 12.

Neonatal Paediatrics, Auckland District Health Board, Auckland, New Zealand.

Background: In 25% of affected babies, neonatal encephalopathy results from acute peripartum events, but rigorous review of these cases for quality improvement is seldom reported. New Zealand has maintained a national database of all babies diagnosed with Sarnat moderate and severe neonatal encephalopathy since 2010 under the Perinatal and Maternal Mortality Review Committee.

Aims: To determine the rate of contributory factors, potentially avoidable mortality or morbidity, and to identify key areas for improvements to maternity and neonatal care among cases of neonatal encephalopathy following an acute peripartum event. Read More

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http://dx.doi.org/10.1111/ajo.12957DOI Listing
February 2019

Non-nursing tasks as experienced by nurses: a descriptive qualitative study.

Int Nurs Rev 2019 Feb 12. Epub 2019 Feb 12.

Nursing Science, University of Udine, Udine, Italy.

Background: Different concepts have been used to date (e.g. non-nursing tasks, organizational work) to define tasks performed by clinical nurses other than nursing care. Read More

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http://dx.doi.org/10.1111/inr.12496DOI Listing
February 2019
1 Read

Implementing Home Blood Pressure Monitoring into Clinical Practice.

Curr Hypertens Rep 2019 Feb 12;21(2):14. Epub 2019 Feb 12.

Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 W.168th Street, PH9-311, New York, NY, 10032, USA.

Purpose Of Review: To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice.

Recent Findings: HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition, there is high-quality evidence that HBPM combined with clinical support improves blood pressure control. Read More

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http://dx.doi.org/10.1007/s11906-019-0916-0DOI Listing
February 2019

Whose harm? Which metaphysic?

Authors:
Abram Brummett

Theor Med Bioeth 2019 Feb 12. Epub 2019 Feb 12.

Albert Gnaegi Center for Health Care Ethics, Saint Louis University, Saint Louis, MO, USA.

Douglas Diekema has argued that it is not the best interest standard, but the harm principle that serves as the moral basis for ethicists, clinicians, and the courts to trigger state intervention to limit parental authority in the clinic. Diekema claims the harm principle is especially effective in justifying state intervention in cases of religiously motivated medical neglect in pediatrics involving Jehovah's Witnesses and Christian Scientists. I argue that Diekema has not articulated a harm principle that is capable of justifying state intervention in these cases. Read More

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http://dx.doi.org/10.1007/s11017-019-09480-1DOI Listing
February 2019

An investigation into specialty trainee engagement with e-learning.

Br J Hosp Med (Lond) 2019 Feb;80(2):105-108

Consultant Neonatologist, Department of Neonatal Care, Liverpool Women's NHS Foundation Trust, Liverpool.

Aim:: The objectives of this study were to determine paediatric specialty trainees' engagement with e-learning in Health Education England North West and the characteristics of sites accessed by specialty trainees, and to assess the quality of web interfaces being used and whether this aligns with the best evidence for e-learning provision.

Methods:: A two-phase mixed methods design was used: a scoping exercise to elicit specialty trainees' preferred e-learning tools and a quality assessment of the named sites, and specialty trainee telephone interviews.

Results:: A total of 135 respondents identified 86 sites. Read More

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http://dx.doi.org/10.12968/hmed.2019.80.2.105DOI Listing
February 2019

Standards for distribution models in biodiversity assessments.

Sci Adv 2019 Jan 16;5(1):eaat4858. Epub 2019 Jan 16.

Center for Macroecology, Evolution and Climate, Natural History Museum of Denmark, University of Copenhagen, DK-2100 Copenhagen, Denmark.

Demand for models in biodiversity assessments is rising, but which models are adequate for the task? We propose a set of best-practice standards and detailed guidelines enabling scoring of studies based on species distribution models for use in biodiversity assessments. We reviewed and scored 400 modeling studies over the past 20 years using the proposed standards and guidelines. We detected low model adequacy overall, but with a marked tendency of improvement over time in model building and, to a lesser degree, in biological data and model evaluation. Read More

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http://dx.doi.org/10.1126/sciadv.aat4858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357756PMC
January 2019

Male Infertility, Precision Medicine and Systems Proteomics.

J Reprod Infertil 2018 Oct-Dec;19(4):185-192

Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Precision medicine (PM) is an approach that has the power to create the best effect and safety of medicine and treatment with the least side effects for each person. PM is very helpful as sometimes due to inaccurate or late diagnosis or toxicities of the drugs irreversible side effect for patient's health are generated. This seemingly new and emerging science is also effective in preventing disease, due to differences in the genes, environment, and lifestyles of any particular person. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328981PMC
February 2019

Computational fluid dynamics in the numerical simulation analysis of end-to-side anastomosis for coarctation of the aorta.

J Thorac Dis 2018 Dec;10(12):6578-6584

Department of Surgery, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou 450018, China.

Background: Based on CT image data, a computational fluid dynamics (CFD) model of the aortic arch was established. We aimed to investigate the hemodynamic features associated with end-to-side anastomosis (ESA) surgery for coarctation of the aorta (CoA) by CFD model.

Methods: The data of enhanced CT two-dimensional medical images obtained through clinical practice were processed using medical image post-processing software. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344770PMC
December 2018

Algorithm for Calculating the Protein Intake in Enteral and Parenteral Nutrition in Premature Infants.

Curr Health Sci J 2018 Apr-Jun;44(2):157-165. Epub 2018 Mar 27.

Department of Pediatric Surgery, University of Medicine and Pharmacy of Craiova.

Introduction: Calculating the exact nutritional balance especially for the premature infant has always been a challenge for the daily practice of the clinician.

Purpose: we intend to establish a simplified formula and mathematical algorithms to calculate the necessary amino acids and proteins for the nutrition of the premature newborn, covering most of the international recommendations and also to give to the neonatal intensive care physician the opportunity of their rapid customization for each case.

Methods: following an extensive literature revision we have established the protein intake recommendations, indications and contraindications for enteral and parenteral nutrition in premature infants, by age of gestation, birth weight and postnatal age. Read More

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http://dx.doi.org/10.12865/CHSJ.44.02.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320467PMC

Antipsychotic augmentation in the treatment of obsessive-compulsive disorder.

Indian J Psychiatry 2019 Jan;61(Suppl 1):S51-S57

Department of Psychiatry, OCD Clinic, NIMHANS, Bengaluru, Karnataka, India.

Most studies suggest that obsessive-compulsive disorder runs a chronic course. Only 40%-70% of patients respond to first-line treatment with selective serotonin reuptake inhibitors (SSRIs). The most common pharmacological strategy used in clinical practice for partial responders to SSRIs is augmentation with an atypical antipsychotic. Read More

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http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_519_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343405PMC
January 2019

Integrated specialty pharmacy yields high PCSK9 inhibitor access and initiation rates.

J Clin Lipidol 2019 Jan 14. Epub 2019 Jan 14.

Specialty Pharmacy Services, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

Background: Access to proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors that lower low-density lipoprotein cholesterol in patients at high risk of atherosclerotic cardiovascular disease events has proven challenging. Methods to overcome access barriers are needed to fully realize the benefits of these novel agents.

Objective: This study evaluated medication access rates in patients prescribed a PCSK9 inhibitor at a health care system with integrated specialty pharmacy services. Read More

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http://dx.doi.org/10.1016/j.jacl.2019.01.003DOI Listing
January 2019

How Are Patients With Prostate Cancer Managing Androgen Deprivation Therapy Side Effects?

Clin Genitourin Cancer 2018 Dec 20. Epub 2018 Dec 20.

University of Calgary, Calgary, AB, Canada; Tom Baker Cancer Centre, Calgary, AB, Canada. Electronic address:

Background: Androgen deprivation therapy (ADT) for prostate cancer has numerous side effects. Clinical guidelines for side effect management exist; however, these are not always integrated into routine practice. What remains undocumented and therefore the objective of this study, is to describe patients' willingness to employ established strategies. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15587673183072
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http://dx.doi.org/10.1016/j.clgc.2018.12.006DOI Listing
December 2018
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1.693 Impact Factor

Use of Abdominal Binders for Postoperative Pain After Gastrointestinal Surgery: An Integrative Review.

J Perianesth Nurs 2019 Feb 7. Epub 2019 Feb 7.

Purpose: No national policies or clinical practice guidelines have been identified regarding best practices in addressing postoperative pain after abdominal surgery with adjunctive nonpharmacologic therapies, such as abdominal binders.

Design: Integrative review.

Methods: An integrative review was conducted using Cochrane, PubMed, Medline, and Cumulative Index to Nursing and Allied Health Literature databases, collecting articles published within the last 5 years regarding abdominal binder use after adult gastrointestinal surgeries. Read More

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http://dx.doi.org/10.1016/j.jopan.2018.10.010DOI Listing
February 2019

ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and the Society of Thoracic Surgeons.

J Am Soc Echocardiogr 2019 Feb 7. Epub 2019 Feb 7.

This document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. The first document addresses the evaluation and use of multimodality imaging in the diagnosis and management of valvular heart disease, whereas this document addresses this topic with regard to structural (nonvalvular) heart disease. While dealing with different subjects, the 2 documents do share a common structure and feature some clinical overlap. Read More

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http://dx.doi.org/10.1016/j.echo.2019.01.008DOI Listing
February 2019