162,088 results match your criteria Best Practice & Research: Clinical Endocrinology & Metabolism[Journal]


Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study.

BMJ Open 2019 Mar 15;9(3):e024159. Epub 2019 Mar 15.

Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada.

Objective: To compare and contrast illustrative examples of the adoption of high value practices and the de-adoption of low value practices.

Design: (1) Retrospective, population-based audit of low molecular weight heparin (LMWH) for venous thromboembolism (VTE) prophylaxis (high value practice) and albumin for fluid resuscitation (low value practice) and (2) cross-sectional survey of healthcare providers.

Setting: Data were collected from nine adult medical-surgical intensive care units (ICUs) in two large Canadian cities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-024159DOI Listing

Economic evaluations of public health implementation-interventions: a systematic review and guideline for practice.

Public Health 2019 Mar 13;169:101-113. Epub 2019 Mar 13.

School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales 2308, Australia; Hunter Medical Research Institute, Newcastle, New South Wales 2305, Australia; Priority Research Centre for Health Behaviour, University of Newcastle, New South Wales 2308, Australia; Hunter New England Population Health, Wallsend, New South Wales 2287, Australia. Electronic address:

Objectives: Implementation interventions applied in public health are about using proven strategies to influence the uptake of evidence-based prevention and health promotion initiatives. The decision to invest in implementation has an opportunity cost, which can be overlooked. The purpose of this study was to assess the extent to which economic evaluations have been applied to implementation interventions in public health. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.puhe.2019.01.012DOI Listing

The gambling craving experience questionnaire: Psychometric properties of a new scale based on the elaborated intrusion theory of desire.

Addict Behav 2019 Feb 27;95:110-117. Epub 2019 Feb 27.

Psychological Sciences Research Institute, Université catholique de Louvain, Louvain-la-Neuve, Belgium; Addictive and Compulsive Behaviours Lab, Institute for Health and Behaviour, University of Luxembourg, Luxembourg; Centre for Excessive Gambling, Lausanne University Hospitals (CHUV), Switzerland.

Both research and clinical practice acknowledge the importance of craving as a maintenance and relapse factor in gambling disorder. The elaborated intrusion theory (EIT; Kavanagh et al., 2005) of desire has been extensively investigated in relation to psychoactive substance or food cravings but, to date, has scarcely been studied in relation to gambling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addbeh.2019.02.023DOI Listing
February 2019

Switching between P2Y inhibitors: Rationale, methods, and expected consequences.

Vascul Pharmacol 2019 Mar 12. Epub 2019 Mar 12.

Cardiology Division, CAST Policlinico Hospital, University of Catania, Catania, Italy.

The pharmacological and clinical differences of the three oral P2Y inhibitors (clopidogrel, prasugrel, ticagrelor) enable physicians to switch from one agent to another that it is considered more appropriate in the specific clinical setting. Moreover, the recent availability of cangrelor, the only intravenous P2Y inhibitor with a rapid onset and offset of its antiplatelet action, makes it necessary to switch from this agent to an oral P2Y inhibitor for a continued platelet inhibition after percutaneous coronary intervention. Several pharmacodynamic studies have provided information on how to change drug, in terms of timing and dosage, without running the risk of a temporary impairment of platelet inhibition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vph.2019.03.001DOI Listing

Population-based patterns of treatment and survival for patients with stage I and II non-small cell lung cancer aged 65-74 years and 75 years or older.

J Geriatr Oncol 2019 Mar 12. Epub 2019 Mar 12.

Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, the Netherlands; Department of Epidemiology, Maastricht University Medical Centre+, GROW School for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address:

Objectives: Insights regarding utilization and survival of surgery and radiotherapy (stereotactic body radiotherapy (SBRT) or conventional radiotherapy (RT)) are lacking for older patients with stage I and II non-small cell lung cancer (NSCLC) in clinical practice.

Methods: Data from the Netherlands Cancer Registry were retrieved for patients ≥65 years with clinical stage I-II NSCLC in 2010-2015. Descriptive analyses, overall survival (OS), and cox regression were stratified for stage I (n = 8742) and II (n = 3439) and compared age groups (65-74 years vs ≥75 years). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgo.2019.03.001DOI Listing

Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study.

Lancet Respir Med 2019 Mar 12. Epub 2019 Mar 12.

University of Arizona College of Medicine, Department of Medicine, Tucson, AZ, USA.

Background: Small airways dysfunction (SAD) is well recognised in asthma, yet its role in the severity and control of asthma is unclear. This study aimed to assess which combination of biomarkers, physiological tests, and imaging markers best measure the presence and extent of SAD in patients with asthma.

Methods: In this baseline assessment of a multinational prospective cohort study (the Assessment of Small Airways Involvement in Asthma [ATLANTIS] study), we recruited participants with and without asthma (defined as Global Initiative for Asthma severity stages 1-5) from general practices, the databases of chest physicians, and advertisements at 29 centres across nine countries (Brazil, China, Germany, Italy, Spain, the Netherlands, the UK, the USA, and Canada). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(19)30049-9DOI Listing

On the removal of initial state bias from simulation data.

J Chem Phys 2019 Mar;150(10):104105

University of Zurich, Department of Biochemistry, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

Classical atomistic simulations of biomolecules play an increasingly important role in molecular life science. The structure of current computing architectures favors methods that run multiple trajectories at once without requiring extensive communication between them. Many advanced sampling strategies in the field fit this mold. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1063/1.5063556DOI Listing

PTSD symptom profiles among Louisiana women affected by the 2010 Deepwater Horizon Oil Spill: A latent profile analysis.

J Affect Disord 2019 Mar 6;250:289-297. Epub 2019 Mar 6.

Epidemiology Program, Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, United States. Electronic address:

Background: Few prior studies have investigated the latent class structure of PTSD using DSM-5 symptoms.

Methods: To describe latent PTSD profiles among women who resided in Deepwater Horizon Oil Spill (DHOS)-affected coastal Louisiana communities, we used data from women enrolled in The Women and Their Children's Health (WaTCH) Study. Latent profile analysis was performed on the 20-item PTSD Checklist for DSM-5 (PCL-5) and model fit statistics for 2-class through 6-class solutions were compared. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jad.2019.03.018DOI Listing

Clinical decision support for high-cost imaging: A randomized clinical trial.

PLoS One 2019 15;14(3):e0213373. Epub 2019 Mar 15.

Department of Economics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

There is widespread concern over the health risks and healthcare costs from potentially inappropriate high-cost imaging. As a result, the Centers for Medicare and Medicaid Services (CMS) will soon require high-cost imaging orders to be accompanied by Clinical Decision Support (CDS): software that provides appropriateness information at the time orders are placed via a best practice alert for targeted (i.e. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213373PLOS

Legal challenges for the implementation of advanced clinical digital decision support systems in Europe.

J Clin Transl Res 2018 Dec 18;3(Suppl 3):424-430. Epub 2018 Aug 18.

Department of Public Health, Academic Medical Center, University of Amsterdam, the Netherlands.

Systems based on artificial intelligence and machine learning that facilitate decision making in health care are promising new tools in the era of 'personalized' or 'precision' medicine. As the volume of patient data and scientific evidence grows, these computerised decision support systems (DSS) have great potential to help healthcare professionals improve diagnosis and care for individual patients. However, the implementation of these tools in clinical care raises some foreseeable legal challenges for healthcare providers and DSS-suppliers in Europe: How does the use of complex and novel DSS relate to professional standards to provide a reasonable standard of care? What should be done in terms of testing before DSS can be used in regular practice? What are the potential liabilities of health care providers and DSS companies if a DSS fails to function well? How do legal requirements for the protection of patient data and general privacy rights apply to likely DSS scenarios? In this article, we provide an overview of the current law and its general implications for the use of DSS, from a European perspective. Read More

View Article

Download full-text PDF

Source
December 2018

Being Nice Is Not Enough-Exploring Relationship-Centered Veterinary Care With Structural Equation Modeling. A Quantitative Study on German Pet Owners' Perception.

Front Vet Sci 2019 28;6:56. Epub 2019 Feb 28.

Department of Veterinary Medicine, Institute for Veterinary Epidemiology and Biostatistics, Freie Universität Berlin, Berlin, Germany.

During the last years, the philosophy of relationship-centered care gained increasing attention in veterinary medicine. Relationship-centered care is based on a joint venture between pet owner and veterinarians and therefore offers the opportunity to satisfy the pet owners' need for participation in medical decision-making and to provide the best care for the patient. Although research on relationship-centered care in the veterinary consultation is still limited, the available findings suggest that the characteristics of relationship-centered care reflect the pet owners' expectations on satisfactory veterinary care. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fvets.2019.00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403131PMC
February 2019

National and subnational estimation of the prevalence of peripheral artery disease (PAD) in China: a systematic review and meta-analysis.

J Glob Health 2019 Jun;9(1):010601

Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.

Background: Peripheral artery disease (PAD), the third leading cause of atherosclerotic vascular morbidity, affects approximately 202 million people worldwide, among whom more than two-thirds reside in low- and middle-income countries (LMIC). For China, the largest developing country, little is known about the epidemiology of PAD. We aimed to estimate the prevalence of PAD and the number of affected people in China, establish the main risk factors for PAD and assess the number of people with PAD at the sub-national level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7189/jogh.09.010601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377796PMC

Sudden Cardiac Death in Dialysis: Arrhythmic Mechanisms and the Value of Non-invasive Electrophysiology.

Front Physiol 2019 25;10:144. Epub 2019 Feb 25.

National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Sudden Cardiac Death (SCD) is the leading cause of cardiovascular death in dialysis patients. This review discusses potential underlying arrhythmic mechanisms of SCD in the dialysis population. It examines recent evidence from studies using implantable loop recorders and from electrophysiological studies in experimental animal models of chronic kidney disease. Read More

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fphys.2019.00144
Publisher Site
http://dx.doi.org/10.3389/fphys.2019.00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401645PMC
February 2019
1 Read

Evolution to a Competency-Based Training Curriculum for Pharmaceutical Medicine Physicians in Switzerland.

Front Pharmacol 2019 27;10:164. Epub 2019 Feb 27.

F. Hoffmann-La Roche Ltd., Basel, Switzerland.

In Switzerland, Pharmaceutical Medicine has existed as one of 46 physician specialties accredited by the Federal Office of Public Health for more than 20 years. As a medical-scientific discipline, our goal is to enable best possible therapeutic coverage for the benefit of patients and society through a medical need-based development and optimal use of medicinal products. The role of the specialist in Pharmaceutical Medicine is to closely collaborate with various stakeholders of the healthcare system in the context of the discovery, research, development and approval of new medicinal products, as well as safe and effective use of new and established medicinal products in daily clinical practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2019.00164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400888PMC
February 2019

Critiquing Research Evidence for Use in Practice: Revisited.

J Pediatr Health Care 2019 Mar 11. Epub 2019 Mar 11.

Nurse practitioners need to critically appraise the abundance of research evidence and clinical practice guidelines to make astute decisions about the implementation of the best available evidence to clinical practice. There are numerous ways to appraise research and practice guidelines that are designed to inform clinical practice with the overall goals of improving patient outcomes. This article presents existing tools to appraise the research evidence in addition to a guide for providers on critical appraisal of a research study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pedhc.2019.01.005DOI Listing

A scoping review of best practice guidelines for the dietary management of diabetes in older adults in residential aged care.

Prim Care Diabetes 2019 Mar 11. Epub 2019 Mar 11.

Nutrition and Dietetics, Flinders University, GPO Box 2100 Adelaide, South Australia 5001, Australia. Electronic address:

Over the last two decades guidelines have been published on the subject of the care and liberalised nutrition management of older adults with diabetes in residential aged care, recognising that they may have different needs to those older adults in their own home. This study aimed to scope and appraise these guidelines using the AGREE II tool. Overall physician developed guidelines were more robust, but there was discordance in their recommendations compared to guidelines developed by dietitians; particularly regarding the use of therapeutic diets. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pcd.2019.02.005DOI Listing

The role of implementation science in improving distress assessment and management in oncology: a commentary on "Screening for psychosocial distress among patients with cancer: implications for clinical practice, healthcare policy, and dissemination to enhance cancer survivorship".

Transl Behav Med 2019 Mar;9(2):292-295

Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.

Despite considerable evidence that psychosocial interventions can effectively relieve distress in patients with cancer, many individuals who could benefit from these interventions do not receive them. A proposed solution to this problem is the establishment of programs in oncology settings that routinely screen for distress and refer patients for appropriate psychosocial care. This commentary addresses a review by Ehlers et al. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/tbm/ibz022DOI Listing

How Do We Know That Our Patients Have Benefitted From Our ENT/Audiological Interventions? Presented at the Annual Meeting of ADANO 2016 in Berlin.

Otol Neurotol 2019 Apr;40(4):e474-e481

National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Ropewalk House.

: This short review article gives an introduction to some of the fundamental concepts and challenges facing measurement in hearing healthcare practice and research. The impact of hearing loss almost always extends beyond the sensory impairment itself, even when the measured degree of audiometric loss is mild. Yet, going beyond audibility, into the realm of measuring impact, takes us into a much more complex and less well-defined space. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MAO.0000000000001937DOI Listing

Delirium screening in patients in a palliative care ward: a best practice implementation project.

JBI Database System Rev Implement Rep 2019 Mar;17(3):429-441

Joanna Briggs Institute, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.

Objectives: The objective was to promote evidence-based practice in screening for delirium in patients in the palliative care ward of a cancer hospital in Shanghai.

Introduction: Delirium is common but under recognized among patients in palliative care settings. Early detection is essential for timely management. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11124/JBISRIR-2017-003646DOI Listing

Prevention and management of primary postpartum hemorrhage among puerperae in a teaching hospital in São Paulo, Brazil: a best practice implementation project.

JBI Database System Rev Implement Rep 2019 Mar;17(3):414-428

The Brazilian Centre for Evidence-informed Healthcare: a Joanna Briggs Institute Centre of Excellence, São Paulo, Brazil.

Objectives: The aim of this project was to develop and implement strategies to promote standardization and formal documentation of increased bleeding within the first 24 h after birth, in compliance with best practice.

Introduction: Official data from Brazil shows a maternal mortality rate of around 52 to 75 deaths per 100,000 live births, 8% of which are caused by hemorrhage. Early diagnosis is promoted through standardization and formal documentation of the first signs of hemorrhage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11124/JBISRIR-2017-003830DOI Listing

Incidence and prevalence of falls in adults with intellectual disability living in the community: a systematic review.

JBI Database System Rev Implement Rep 2019 Mar;17(3):390-413

School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia.

Objective: The objective of the review was too synthesize the best available evidence on the incidence and prevalence of falls among adults with intellectual disability (ID).

Introduction: Falls among adults with ID frequently cause physical injury and may negatively impact on their quality of life. Studies investigating falls among people with ID have used differing methods and populations, making it difficult to determine the scope and extent of this problem. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11124/JBISRIR-2017-003798DOI Listing

Race, Research, and Women's Health: Best Practice Guidelines for Investigators.

Obstet Gynecol 2019 Mar 11. Epub 2019 Mar 11.

Warren Alpert Medical School of Brown University, Women & Infants Hospital of Rhode Island, and the Providence Community Health Centers, Providence, Rhode Island.

Medicine has a complex history of mishandling the concept of race. This is a crucial time for the field of obstetrics and gynecology to address racial and ethnic disparities. In this commentary, we address misconceptions about race, show how race can be misused in research and clinical care, and suggest new standards to guide authors as they conduct research on disparities and race. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003157DOI Listing

The discovery and development of topical medicines for wound healing.

Expert Opin Drug Discov 2019 Mar 14:1-13. Epub 2019 Mar 14.

a Department of Medical Cell Biology , Uppsala University , Uppsala , Sweden.

Introduction: Chronic, nonhealing skin wounds claim >3% of the health-care budget in industrialized countries, and the incidence is rising. Currently, two parallel trends influence innovations within the field of wound healing: the need to reduce spread of antibiotic resistance and the emerging use of health economy and value-based models. Areas covered: This review focuses on the discovery of drug candidates and development of treatments aiming to enhance wound healing in the heterogeneous group of patients with nonhealing wounds. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/17460441.2019.1
Publisher Site
http://dx.doi.org/10.1080/17460441.2019.1588879DOI Listing
March 2019
1 Read

Interventions for students with autism in inclusive settings: A best-evidence synthesis and meta-analysis.

Psychol Bull 2019 Mar 14. Epub 2019 Mar 14.

Department of Special Education & Multiple Abilities.

Students with autism spectrum disorder (ASD) are increasingly educated alongside typically developing peers in regular education environments. These students have impairments that may hinder their success in inclusive school settings and require individualized supports to improve outcomes. The purpose of this meta-analysis and best-evidence synthesis is to examine the characteristics of interventions for students with ASD in inclusive settings, offer quantitative analysis of intervention effects, examine potential moderating variables that influence outcomes, analyze the social validity of these interventions, and provide recommendations for practice and future research. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1037/bul0000190DOI Listing

Internet-Based Cognitive Behavioral Therapy in Stepped Care for Chronic Fatigue Syndrome: Randomized Noninferiority Trial.

J Med Internet Res 2019 Mar 14;21(3):e11276. Epub 2019 Mar 14.

Department of Medical Psychology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.

Background: Internet-based cognitive behavioral therapy (I-CBT) leads to a reduction of fatigue severity and disability in adults with chronic fatigue syndrome (CFS). However, not all patients profit and it remains unclear how I-CBT is best embedded in the care of CFS patients.

Objective: This study aimed to compare the efficacy of stepped care, using therapist-assisted I-CBT, followed by face-to-face (f2f) cognitive behavioral therapy (CBT) when needed, with f2f CBT (treatment as usual [TAU]) on fatigue severity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2196/11276DOI Listing

Applying educational theories into planning a psychomotor learning activity: an undergraduate neonatal resuscitation programme experience.

Arch Argent Pediatr 2019 Apr;117(2):e181-e187

Centro Educativo de la Universidad Médica Internacional, Malaysia.

The Neonatal Resuscitation Programme is a good example of an effective educational intervention that has improved perinatal mortality rates in many countries. This paper shares our experience of planning an undergraduate Neonatal Resuscitation Programme using basic principles of education theory of spiral curriculum, Bloom's taxonomy in planning learning outcomes, Kolb's learning model and Miller's model of clinical assessment. Engaging clinicians in pedagogical theories may not be well aligned with how clinicians traditionally thought they learnt best, yet it is key to improving learning concept and educational intervention outcomes in the healthcare professions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5546/aap.2019.eng.e181DOI Listing

Clinical, radiological features and surgical strategies for 23 NF1 patients with intraorbital meningoencephalocele.

Neurol Sci 2019 Mar 13. Epub 2019 Mar 13.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.

Intraorbital meningoencephalocele is a rare manifestation of neurofibromatosis type 1 (NF1) caused by secondary changes in sphenoid dysplasia, and it seriously affects patients' vision and facial appearance. We retrospectively analyzed the clinical data of 23 patients with NF1 and intraorbital meningoencephalocele, summarized the surgical strategies employed, and evaluated their clinical efficacy in order to better understand its management in clinical practice, establish a reasonable surgical strategy, and assess prognosis. Before surgery, 22 patients had unilateral pulsatile exophthalmos, 18 patients had significant visual impairment, and 13 patients had ptosis associated with an orbital plexiform neurofibroma (PNF). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10072-019-03826-2DOI Listing
March 2019
1.495 Impact Factor

Barriers to Accessing Sexual Health Services for Transgender and Male Sex Workers: A Systematic Qualitative Meta-summary.

AIDS Behav 2019 Mar 13. Epub 2019 Mar 13.

School of Public Health, Faculty of Medicine, University of Queensland, Brisbane, Australia.

Access to safe and effective sexual healthcare services for transgender and male sex workers (TMSW) is a human right. Globally, TMSW experience a higher prevalence of human immunodeficiency virus (HIV) and sexually transmitted infections than the general population or other sex workers, suggesting the existence of unique challenges for this group when accessing healthcare. A systematic database search identified 22 qualitative papers addressing barriers to accessing sexual healthcare services for TMSW. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10461-019-02453-4DOI Listing

Methodology for ESR iGuide content.

Authors:

Insights Imaging 2019 Mar 13;10(1):32. Epub 2019 Mar 13.

The European Society of Radiology (ESR) considers the use of evidence-based referral guidelines in clinical practice essential to ensure the appropriate utilisation of medical imaging for patients. Since 2014, the ESR has been working with the American College of Radiology (ACR) to develop referral guidelines for Europe, based on the ACR Appropriateness Criteria (AC) and appropriate use criteria developed by the ACR Rapid Response Committee.This paper sets out the methodology used by the ESR's Referral Guidelines Subcommittee to adapt the ACR criteria for use in the European clinical decision support (CDS) platform ESR iGuide. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13244-019-0720-zDOI Listing

Regional Catheters for Outpatient Surgery-a Comprehensive Review.

Curr Pain Headache Rep 2019 Mar 14;23(4):24. Epub 2019 Mar 14.

Department of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.

Purpose Of Review: This review summarizes and discusses the history of continuous catheter blockade (CCB), its current applications, clinical considerations, economic benefits, potential complications, patient education, and best practice techniques.

Recent Findings: Regional catheters for outpatient surgery have greatly impacted acute post-operative pain management and recovery. Prior to development, options for acute pain management were limited to the use of opioid pain medications, NSAIDS, neuropathic agents, and the like as local anesthetic duration of action is limited to 4-8 h. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11916-019-0762-4
Publisher Site
http://dx.doi.org/10.1007/s11916-019-0762-4DOI Listing
March 2019
1 Read

Epilepsy in tuberous sclerosis complex: Findings from the TOSCA Study.

Epilepsia Open 2019 Mar 21;4(1):73-84. Epub 2018 Dec 21.

Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre St Georges University of London London UK.

Objective: To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC).

Methods: Retrospective and prospective patients' data on all aspects of TSC were collected from multiple countries worldwide. Epilepsy variables included seizure type, age at onset, type of treatment, and treatment outcomes and association with genotype, seizures control, and intellectual disability. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/epi4.12286
Publisher Site
http://dx.doi.org/10.1002/epi4.12286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398114PMC
March 2019
2 Reads

Analgesia for lumbar puncture in infants and children.

Authors:
Ran D Goldman

Can Fam Physician 2019 Mar;65(3):192-194

As a family physician who works in the local community emergency department, my skills include performing lumbar puncture in young children and infants. I hear conflicting recommendations in regard to provision of analgesia during lumbar puncture in these patients. Does local analgesia affect the success rate of the procedure? What is the best practice for analgesia in young children and infants? Lumbar puncture is one of the most commonly encountered painful procedures in pediatric medicine; it is imperative for timely diagnosis of central nervous system infections in febrile young infants. Read More

View Article

Download full-text PDF

Source

Addressing vaccine hesitancy: Clinical guidance for primary care physicians working with parents.

Can Fam Physician 2019 Mar;65(3):175-181

Associate Medical Officer of Health with Toronto Public Health and Adjunct Professor in the Dalla Lana School of Public Health at the University of Toronto.

Objective: To provide primary care physicians with clinical guidance for addressing parental vaccine hesitancy.

Sources Of Information: The PubMed database was searched for English-language articles published in the 10 years before January 1, 2018. Search terms included or or or and or . Read More

View Article

Download full-text PDF

Source
March 2019
1 Read

A Qualitative Study of Independent Home Visits by Hospice Fellows: Addressing Gaps in ACGME Milestones by Fostering Reflection and Self-Assessment.

Am J Hosp Palliat Care 2019 Mar 13:1049909119836218. Epub 2019 Mar 13.

1 Cleveland Clinic, Cleveland, OH, USA.

Background:: With the rapid growth in the number of fellowship programs in Hospice and Palliative Medicine (HPM), many are in the process of developing ways to demonstrate that fellows are attaining educational milestones. Reflection and self-assessment are key components of 2 Accreditation Council for Graduate Medical Education (ACGME) competencies, practice-based learning and improvement, and systems-based practice, which have both been historically challenging to learn and assess.

Objective:: This article describes results of a content analysis of narrative data collected from HPM fellows' self-assessments as they performed hospice home visits independently in a new clinical rotation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1049909119836218DOI Listing

10-MDP Based Dental Adhesives: Adhesive Interface Characterization and Adhesive Stability-A Systematic Review.

Materials (Basel) 2019 Mar 7;12(5). Epub 2019 Mar 7.

Faculty of Medicine, University of Coimbra, 3000-354 Coimbra, Portugal.

The incorporation of functional monomers in dental adhesive systems promotes chemical interaction with dental substrates, resulting in higher adhesion forces when compared to micromechanical adhesion only. The 10-MDP monomer, whose chemical structure allows for a polar behavior which is favorable to adhesion, also promotes the protection of collagen fibers through the formation of MDP-calcium salts. This systematic review aimed to characterize the interface created by 10-MDP containing adhesive systems through an evaluation of the following parameters: Formation of nano-layered structures, capacity to produce an acid-base resistant zone, and adhesion stability. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma12050790DOI Listing

Association of Appendicular Lean Mass, Subcutaneous and Visceral Adipose Tissue with Mortality in Older Brazilians: The São Paulo Ageing & Health Study.

J Bone Miner Res 2019 Mar 13. Epub 2019 Mar 13.

Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina FMUSP da Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Body composition changes resulting from ageing may impact older adults survival. However, its influence on mortality risk is uncertain. Currently, the best method for body composition analysis in clinical practice is dual energy X-ray absorptiometry (DXA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.3710DOI Listing

Conservation practitioners' understanding of how to manage evolutionary processes.

Conserv Biol 2019 Mar 13. Epub 2019 Mar 13.

School of Biological Sciences, Monash University, Clayton VIC 3800, Australia.

Both academics and practitioners consider a lack of knowledge about evolutionary theory to be a general barrier to effectively managing genetic diversity. However, it is challenging to judge practitioners' level of understanding and how this influences their management decisions. Knowledge built through experience may be difficult for practitioners to articulate, but could nonetheless result in appropriate management strategies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cobi.13306DOI Listing

Health satisfaction and family impact of parents of children with cancer: a descriptive cross-sectional study.

Scand J Caring Sci 2019 Mar 13. Epub 2019 Mar 13.

Psychiatric and Mental Health Nursing, School of Nursing, The University of Jordan, Amman, Jordan.

Background: The impact on parents of coping with a child who has cancer can be both severe and multifarious. Considerable distress persists throughout the treatment phase, persisting even after completion of treatment with heightened anxiety and stress associated with thoughts of recurrence or relapse.

Aim: The purpose was to investigate the links between parents' satisfaction with the health care offered to their child with cancer and the impact on families of caring for such a child (including their health-related quality of life) in a Middle Eastern country. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/scs.12677DOI Listing

[Staphylococcus aureus Bacteraemia - an Interdisciplinary Challenge].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Mar 13;54(3):206-216. Epub 2019 Mar 13.

Background: Staphylococcus aureus is the second-most-common pathogen among bloodstream infections. Due to a high hospital mortality rate (15 - 40%), frequent complications and recurrences the clinical management of Staphylococcus aureus bacteremia (SAB) is distinct from bacteremia from other pathogens.

Methods: A literature search was performed using PubMed. Read More

View Article

Download full-text PDF

Source
http://www.thieme-connect.de/DOI/DOI?10.1055/a-0756-8263
Publisher Site
http://dx.doi.org/10.1055/a-0756-8263DOI Listing
March 2019
5 Reads

The Biomechanics of Breastfeeding: Bridging the Gap between Engineering-Based Studies and Clinical Practice.

Authors:
Mike Woolridge

Nestle Nutr Inst Workshop Ser 2019 13;90:13-32. Epub 2019 Mar 13.

Currently accepted "best practice" for managing breastfeeding effectively (WHO/UNICEF) is largely based on a historical view of how babies remove milk from the breast, which had persisted for several centuries. The collective wisdom was verified by imaging studies in the 1950s and 1980s, to reach a consensus view - clinical management principles, based on such research, have proved highly effective. Over the past decade, the mechanics of suckling, and how the baby removes milk from the breast, have been revisited, using modern imaging technology and by the application of engineering-based techniques, which seek to develop explanatory models of how suckling works. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000490322DOI Listing

Passive sampling of polar emerging contaminants in Irish catchments.

Water Sci Technol 2019 Jan;79(2):218-230

School of Chemical Sciences and Water Institute, Dublin City University, Dublin, Ireland E-mail:

Passive sampling (PS) is a very useful approach for the monitoring of emerging contaminants in environmental matrices, showing greater sensitivity than can be achieved by current best practice - grab sampling - and is applicable to a wide variety of compounds. An EU Directive (2013/39/EC) has added substances to the existing Water Framework Directive (WFD) Priority Substance list. Investigation into PS in the monitoring of these compounds is necessary to show the potential of this technique in supporting monitoring requirements under the WFD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2166/wst.2019.021DOI Listing
January 2019

Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression.

Dermatol Surg 2019 Mar 8. Epub 2019 Mar 8.

Aging and Aneuploidy Group, IBMC, Instituto de Biologia Molecular e Celular, Porto, Portugal.

Background: Appropriate storage of human hair follicle (HF) grafts during follicular unit excision (FUE) is crucial toward successful hair shaft implantation. Several commercial storage solutions are currently used to ensure ex vivo maintenance of follicular grafts viability and trichogenicity. However, quantitative experimental evidence demonstrating molecular changes in HF cells associated with the usage of different storage solutions is largely missing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DSS.0000000000001895DOI Listing

Endoscopic retrograde cholangiopancreatography (ERCP): lessons learned from population-based national registries: a systematic review.

Surg Endosc 2019 Mar 12. Epub 2019 Mar 12.

Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) was introduced more than four decades ago as a diagnostic tool for biliary and pancreatic diseases. Currently, ERCP is mainly used as a therapeutic approach to relieve biliary or pancreatic duct obstruction. Clinical practice has been based on a few large reports and some randomized controlled trials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00464-019-06734-wDOI Listing

Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway.

Front Immunol 2019 26;10:280. Epub 2019 Feb 26.

Cell Biology and Immunology Group, Wageningen University & Research, Wageningen, Netherlands.

Immune-modulatory effects of β-glucans are generally considered beneficial to fish health. Despite the frequent application of β-glucans in aquaculture practice, the exact receptors and downstream signalling remains to be described for fish. In mammals, Dectin-1 is a member of the C-type lectin receptor (CLR) family and the best-described receptor for β-glucans. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400144PMC
February 2019

Free Gracilis Muscle Flap for Sarcoma Reconstruction: 19 Years of Clinical Experience.

Sarcoma 2019 3;2019:3975020. Epub 2019 Feb 3.

Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA.

Background: Sarcoma treatment necessitates high-dose chemoradiation therapy and wide surgical margins that create wounds that are difficult to reconstruct. Many techniques have been developed to cover these defects, originating with muscle flaps such as the rectus abdominis and latissimus dorsi. The gracilis flap, which is best known in contemporary practice as a microneurovascular flap for functional reconstructions, is not usually considered a robust option for reconstruction after sarcoma extirpation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/3975020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378001PMC
February 2019

How multidisciplinary are multidisciplinary team meetings in cancer care? An observational study in oncology departments in Flanders, Belgium.

J Multidiscip Healthc 2019 21;12:159-167. Epub 2019 Feb 21.

Vrije Universiteit Brussel (VUB), Department of Public Health, Research Group Organisation, Policy and Social Inequalities in Health Care (OPIH), 1090 Brussels, Belgium,

Background: In current cancer care, multidisciplinary team meetings (MDTMs) aim at uniting care professionals from different disciplines to decide upon the best possible treatment plan for the patients based on the available scientific evidence. In Belgium, the multidisciplinary approach is mandatory and formally regulated since 2003. Current research indicates that MDTMs are not always truly multidisciplinary, ie, with a mix of medical as well as paramedical disciplines, and that the medical profession (physicians and medical specialists) tends to dominate the interaction in MDTMs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JMDH.S196660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389011PMC
February 2019

Perioperative Surgical Home, Fixing a Fragmented Process to Improve Quality of Care.

Authors:
Michael J Duncan

Mo Med 2019 Jan-Feb;116(1):53-57

Michael J. Duncan, MD, is in the Department of Anesthesiology, Saint Luke's Hospital, University of Missouri - Kansas City, Kansas City, Missouri.

The practice of Perioperative Medicine is in need of greater coordination and organization. The traditional model of perioperative patient care, scheduling surgical care based primarily on surgeon/patient availability, along with the operative need, with little thought for coordination and planning to ensure that patients can safely undergo surgery and expect the best possible outcome, is in need of a paradigm change. Return to the highest level of functionality should be the patient centered approach. Read More

View Article

Download full-text PDF

Source

"Best interest" and pediatric end stage kidney disease: The case of baby M.

Authors:
Andrew Mantulak

J Pediatr Nurs 2019 Mar 9. Epub 2019 Mar 9.

School of Social Work, King's University College at Western University, 266 Epworth Avenue, London, Ontario N6A 2M3, Canada. Electronic address:

In everyday clinical practice, health professionals and parents of chronically ill children often rely on the principle of 'best interest' in the development of medically oriented treatment plans. In most cases, such processes are done collaboratively; however, 'best interest' as a standard for decision-making becomes ambiguous in situations wherein parents and health professionals fail to agree on the course of treatment. This paper will explore the potential tensions that can exist in clinical practice when 'best interest' is used for making health care decisions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pedn.2019.02.032DOI Listing
March 2019
2 Reads

A Clinical Training Program for Hybrid Closed Loop Therapy in a Pediatric Diabetes Clinic.

J Diabetes Sci Technol 2019 Mar 12:1932296819835183. Epub 2019 Mar 12.

1 University of Colorado, Denver, Barbara Davis Center for Childhood Diabetes, Aurora, CO, USA.

Background:: Hybrid closed loop (HCL) therapy is now available in clinical practice for treatment of type 1 diabetes; however, there is limited research on how to educate patients on this new therapy. The purpose of this quality improvement project was to optimize a HCL education program for pediatric patients with type 1 diabetes (T1D).

Methods:: Our multidisciplinary team developed a novel HCL clinical training program for current insulin pump users, using a quality improvement process called the Plan-Do-Study-Act model. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1932296819835183
Publisher Site
http://dx.doi.org/10.1177/1932296819835183DOI Listing
March 2019
1 Read

Implementation and Evaluation of Diabetes Clinical Practice Guidelines in a Primary Care Clinic Serving a Hispanic Community.

Worldviews Evid Based Nurs 2019 Mar 12. Epub 2019 Mar 12.

Capstone College of Nursing, The University of Alabama, Tuscaloosa, AL, USA.

Background: Diabetes is a major health concern in the United States. Poor quality diabetes care leads to negative outcomes affecting patients and healthcare systems. Research shows evidence-based clinical practice guidelines from the American Diabetes Association, Standards of Medical Care in Diabetes-2017, have improved outcomes in management of diabetes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/wvn.12345DOI Listing
March 2019
2 Reads