163,201 results match your criteria Best Practice & Research Clinical Endocrinology & Metabolism[Journal]


Variation in hospital charges in patients with external ventricular drains: comparison between the intensive care and surgical floor settings.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

3Department of Neurosurgery, University of Washington School of Medicine, Seattle, Washington.

OBJECTIVEPlacement of an external ventricular drain (EVD) is a common and potentially life-saving neurosurgical procedure, but the economic aspect of EVD management and the relationship to medical expenditure remain poorly studied. Similarly, interinstitutional practice patterns vary significantly. Whereas some institutions require that patients with EVDs be monitored strictly within the intensive care unit (ICU), other institutions opt primarily for management of EVDs on the surgical floor. Read More

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https://thejns.org/view/journals/j-neurosurg-pediatr/aop/art
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http://dx.doi.org/10.3171/2019.2.PEDS18545DOI Listing
April 2019
1 Read

Indigenous Doulas: A literature review exploring their role and practice in western maternity care.

Midwifery 2019 Apr 16;75:52-58. Epub 2019 Apr 16.

Charles Darwin University, Australia.

Objective: The purpose of this article is to establish a body of literature exploring the emergent topic of Indigenous doulas, in relation to Indigenous communities in remote locations, where women are routinely evacuated and no longer supported to give birth. In doing so the article will synthesise and critique key concepts in the literature and identify gaps for prioritisation in future research.

Design: The methodology is influenced by Indigenous, decolonising and feminist theoretical standpoints. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02666138193008
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http://dx.doi.org/10.1016/j.midw.2019.04.005DOI Listing
April 2019
1 Read

International Board Certified Lactation Consultants' Practices Regarding Supplemental Feeding Methods for Breastfed Infants.

J Hum Lact 2019 Apr 19:890334419835744. Epub 2019 Apr 19.

5 University of Texas Health Science Center San Antonio, School of Nursing, San Antonio, TX, USA.

Background: According to the Baby Friendly Hospital Initiative, when supplementary feeding occurs, mothers should be counseled on the use and risks of feeding bottles and teats. To help support this initiative it is important to understand the supplementation practices of Internationally Board Certified Lactation Consultants (IBCLC)®.

Research Aims: To determine (1) if the location of an IBCLC's practice has any impact on supplemental feeding methods; (2) the preferred methods of and the main reasons for supplementation; (3) the level of an IBCLC's confidence with supplemental feeding methods; (4) who is making supplemental feeding decisions; and (5) if there are geographical differences among supplementation choices and reasons for supplementation. Read More

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http://dx.doi.org/10.1177/0890334419835744DOI Listing

LIDAR explains diversity of plants, fungi, lichens and bryophytes across multiple habitats and large geographic extent.

Ecol Appl 2019 Apr 19:e01907. Epub 2019 Apr 19.

Section for Ecoinformatics and Biodiversity, Department of Bioscience, Aarhus University, Ny Munkegade 114, DK, 8000, Aarhus C, Denmark.

Effective planning and nature management require spatially accurate and comprehensive measures of the factors important for biodiversity. LIDAR (Light detection and ranging) can provide exactly this, and is therefore a promising technology to support future nature management and related applications. However, until now studies evaluating the potential of LIDAR for this field have been highly limited in scope. Read More

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http://dx.doi.org/10.1002/eap.1907DOI Listing

The best perinatal depression screening: Is self-administered PHQ2 more feasible than a nurse-administered one?

Perspect Psychiatr Care 2019 Apr 18. Epub 2019 Apr 18.

Department of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York.

Purpose: To assess perinatal depression screening via self-administered PHQ2 (SAP) vs nurse-administered PHQ2 (NAP).

Design And Methods: NAP screening was performed for 3 months, followed by SAP. Data were gathered from visits at 24 to 28 weeks gestation. Read More

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http://dx.doi.org/10.1111/ppc.12383DOI Listing

Evaluation of giant cell tumors by diffusion weighted imaging-fractional ADC analysis.

Skeletal Radiol 2019 Apr 19. Epub 2019 Apr 19.

Department of Radiology, Musculoskeletal Imaging, UT Southwestern Medical Center, 5323 Harry Hines Blvd, E230-C, Dallas, TX, 75390-9316, USA.

Background: A single ADC value is used in clinical practice on multi b-value acquisitions. Low b-value acquisitions are affected by intravoxel incoherent motion, which is dependent on perfusion. Giant cell tumors (GCTs) are known to exhibit early arterial enhancement and low ADC values. Read More

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http://dx.doi.org/10.1007/s00256-019-03219-8DOI Listing

Service-Learning as a Practical Introduction to Undergraduate Public Health: Benefits for Student Outcomes and Accreditation.

Front Public Health 2019 2;7:63. Epub 2019 Apr 2.

The Center for Community Work and Learning, St. Catherine University, St. Paul, MN, United States.

Since the mid-1980s, service-learning has gained recognition as a pedagogical model in higher education with exciting potential for students' academic, civic, and professional development (1). Deemed a high-impact educational practice by the American Association of Colleges and Universities (AAC&U), extant research points to student learning, engagement, and retention benefits from community-based experiences integrated into curriculum (2, 3). Numerous studies have examined best practices for service-learning from varying stakeholder perspectives (faculty, student, and community partner) and disciplines, however, due to the recent development of public health as a major offering in U. Read More

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https://www.frontiersin.org/article/10.3389/fpubh.2019.00063
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http://dx.doi.org/10.3389/fpubh.2019.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454065PMC
April 2019
1 Read

Neonatal Chylothoraces: A 10-Year Experience in a Tertiary Neonatal Referral Centre.

Case Rep Pediatr 2019 13;2019:3903598. Epub 2019 Mar 13.

Neonatal Intensive Care Centre, Kings College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.

Background: Neonatal chylothorax is a rare condition, but has a high mortality.

Study Objectives: To analyse the outcomes of a series of neonates with chylothorax and review the literature to determine best practice.

Design: A case series review and a literature review using electronic databases including the key words neonates and chylothorax. Read More

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https://www.hindawi.com/journals/cripe/2019/3903598/
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http://dx.doi.org/10.1155/2019/3903598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436362PMC
March 2019
1 Read

The use of chemotherapeutic agents as prophylaxis for recurrent urinary tract infection in healthy nonpregnant women: A network meta-analysis.

Indian J Urol 2019 Apr-Jun;35(2):147-155

Department of Obstetrics and Gynaecology, International Medical University Clinical Campus Seremban, Negeri Sembilan, Malaysia.

Introduction: The aim of this systematic review is to compare chemotherapeutic agents commonly used in treating recurrent urinary infection in nonpregnant women by their efficacy, tolerability, adverse effects, and cost employing network meta-analysis.

Materials And Methods: We used three online databases, i.e. Read More

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http://dx.doi.org/10.4103/iju.IJU_378_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458811PMC
April 2019
1 Read

Protocol-based perioperative antimicrobial prophylaxis in urologic surgeries: Feasibility and lessons learned.

Indian J Urol 2019 Apr-Jun;35(2):141-146

Department of Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Rational use of antibiotics and strict adherence to practice guidelines is essential to prevent antibiotic resistance. The best surgical prophylaxis protocol requires tailoring of the available guidelines in accordance to the local bacterial flora. We designed a protocol for surgical prophylaxis to check the rampant abuse of antibiotics in the department of urology and evaluated its feasibility. Read More

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http://dx.doi.org/10.4103/iju.IJU_270_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458815PMC

Comparison of resting and adenosine-free pressure indices with adenosine-induced hyperemic fractional flow reserve in intermediate coronary lesions.

Indian Heart J 2019 Jan - Feb;71(1):74-79. Epub 2018 Dec 10.

Department of Cardiology, Institute of Cardio-Vascular Diseases, Madras Medical Mission, Chennai, Tamilnadu, India. Electronic address:

Objective: Fractional flow reserve (FFR) using adenosine has been the gold standard in the functional assessment of intermediate coronary stenoses in the catheterization laboratory. We aim to study the correlation of adenosine-free indices such as whole cycle Pd/Pa [the ratio of mean distal coronary pressure (Pd) to the mean pressure observed in the aorta (Pa)], instantaneous wave-free ratio (iFR), and contrast-induced submaximal hyperemia (cFFR) with FFR.

Methods: This multicenter, prospective, observational study included patients with stable angina or acute coronary syndrome (>48 h since onset) with discrete intermediate coronary lesions (40-70% diameter stenosis). Read More

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http://dx.doi.org/10.1016/j.ihj.2018.11.016DOI Listing
December 2018

Training through malaria research: building capacity in good clinical and laboratory practice in Liberia.

Malar J 2019 Apr 17;18(1):136. Epub 2019 Apr 17.

ISGlobal, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

Background: Limited health research capacities (HRC) undermine a country's ability to identify and adequately respond to local health needs. Although numerous interventions to strengthen HRC have been conducted in Africa, there is a need to share the lessons learnt by funding organizations, institutes and researchers. The aim of this report is to identify best practices in HRC strengthening by describing a training programme conducted between 2016 and 2017 at the Saint Joseph's Catholic Hospital (SJCH) in Monrovia (Liberia). Read More

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http://dx.doi.org/10.1186/s12936-019-2767-1DOI Listing

Switching to Clopidogrel in Patients With Acute Coronary Syndrome Managed With Percutaneous Coronary Intervention Initially Treated With Prasugrel or Ticagrelor: Systematic Review and Meta-analysis.

Ann Pharmacother 2019 Apr 18:1060028019845334. Epub 2019 Apr 18.

3 University of Alberta, Edmonton, AB, Canada.

Objective: To evaluate the effects of switching from ticagrelor or prasugrel to clopidogrel in acute coronary syndrome (ACS) patients managed with percutaneous coronary intervention on major adverse cardiovascular events (MACEs) and bleeding.

Data Sources: We searched MEDLINE, EMBASE, CENTRAL, bibliographies of relevant articles, and clinicaltrials.gov for eligible articles published from inception to January 27, 2019. Read More

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http://dx.doi.org/10.1177/1060028019845334DOI Listing

Machine Learning Techniques in Concrete Mix Design.

Materials (Basel) 2019 Apr 17;12(8). Epub 2019 Apr 17.

Faculty of Civil and Environmental Engineering, Gdansk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdansk, Poland.

Concrete mix design is a complex and multistage process in which we try to find the best composition of ingredients to create good performing concrete. In contemporary literature, as well as in state-of-the-art corporate practice, there are some methods of concrete mix design, from which the most popular are methods derived from The Three Equation Method. One of the most important features of concrete is compressive strength, which determines the concrete class. Read More

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http://dx.doi.org/10.3390/ma12081256DOI Listing

Advisory workgroup recommendations on the use of clinical simulation in respiratory therapy education.

Can J Respir Ther 2016 1;52(4):114-117. Epub 2016 Nov 1.

College of the North Atlantic, St. John's, Newfoundland and Labrador.

Clinical simulation has become established as a commonly used educational approach in respiratory therapy, though questions remain with regards to the evidence basis for its use in some contexts. In conjunction with the development of a new iteration of the National Competency Framework (NCF), the National Alliance of Respiratory Therapy Regulatory Bodies (NARTRB) reaffirmed its desire to continue to recognize the use of simulation as an educational tool. Given the expressed uncertainty as to best practices in the use of clinical simulation in entry-to-practice respiratory therapy education programs, the NARTRB requested the creation of an expert workgroup to develop a list of recommendations from which an implementation plan could be developed for the next iteration of the NCF. Read More

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November 2016

Reconciling Autonomy and Beneficence in Treatment Decision-Making for Companion Animal Patients.

Liverp Law Rev 2018 2;39(1):47-69. Epub 2018 Jun 2.

3Centre for Applied Bioethics, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.

This article explores how the concept of consent to medical treatment applies in the veterinary context, and aims to evaluate normative justifications for owner consent to treatment of animal patients. We trace the evolution of the test for valid consent in human health decision-making, against a backdrop of increased recognition of the importance of patient rights and a gradual judicial espousal of a doctrine of informed consent grounded in a particular understanding of autonomy. We argue that, notwithstanding the adoption of a similar discourse of informed consent in professional veterinary codes, notions of autonomy and informed consent are not easily transferrable to the veterinary medicine context, given inter alia the tripartite relationship between veterinary professional, owner and animal patient. Read More

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http://dx.doi.org/10.1007/s10991-018-9211-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435006PMC

Multicenter evaluation of a novel ROS1 immunohistochemistry assay (SP384) for detection of ROS1 rearrangements in a large cohort of lung adenocarcinoma patients.

J Thorac Oncol 2019 Apr 15. Epub 2019 Apr 15.

Université Côte d'Azur, University Hospital Federation OncoAge, Laboratory of Clinical and Experimental Pathology, Pasteur Hospital, Nice, France;; Université Côte d'Azur, CNRS, INSERM, Institute of Research on Cancer and Ageing of Nice (IRCAN), University Hospital Federation OncoAge, Nice, France;; Université Côte d'Azur, University Hospital Federation OncoAge, Hospital-Related Biobank (BB-0033-00025), Pasteur Hospital, Nice, France;. Electronic address:

Introduction: The detection of a ROS1 rearrangement in advanced and metastatic lung adenocarcinoma (LUAD) lead to a targeted treatment with tyrosine kinase inhibitors, with favorable progression-free survival and overall survival of the patients. Thus, it is mandatory to screen for the ROS1 rearrangement in all these patients. ROS1 rearrangements can be detected using break-apart fluorescence in situ hybridization (FISH), which is the "gold standard"; however, ROS1 immunohistochemistry (IHC) can be used as a screening test since it is widely available, easy and rapid to perform, and cost-effective. Read More

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http://dx.doi.org/10.1016/j.jtho.2019.03.024DOI Listing

Narrow-band Imaging for Detection of Neoplasia at Colonoscopy: a Meta-analysis of Data From Individual Patients in Randomized Controlled Trials.

Gastroenterology 2019 Apr 15. Epub 2019 Apr 15.

Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford NIHR Biomedical Research Centre, Oxford OX3 9DU, UK. Electronic address:

Background & Aims: Adenoma detection rate (ADR) is an important quality assurance measure for colonoscopy. Some studies suggest that narrow band imaging (NBI) may be more effective at detection of adenomas than white-light endoscopy (WLE) when bowel preparation is optimal. We conducted a meta-analysis of data from individual patients in randomized controlled trials that compared the efficacy of NBI to WLE in detection of adenomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193570
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http://dx.doi.org/10.1053/j.gastro.2019.04.014DOI Listing
April 2019
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Issues and current standards of controls in microbiome research.

FEMS Microbiol Ecol 2019 May;95(5)

Department of Medical Microbiology, Leiden University Medical Center, PO Box 9600, 2300RC, Leiden, The Netherlands.

Good scientific practice is important in all areas of science. In recent years this has gained more and more attention, especially considering the 'scientific reproducibility crisis'. While most researchers are aware of the issues with good scientific practice, not all of these issues are necessarily clear, and the details can be very complicated. Read More

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https://academic.oup.com/femsec/article/doi/10.1093/femsec/f
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http://dx.doi.org/10.1093/femsec/fiz045DOI Listing
May 2019
1 Read

"Posting policies don't change because there is peace or war": the staff deployment challenges for two large health employers during and after conflict in Northern Uganda.

Hum Resour Health 2019 Apr 17;17(1):27. Epub 2019 Apr 17.

ReBUILD Consortium and Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, United Kingdom.

Background: Between 1986 and 2006, the Acholi region in Uganda experienced armed conflict which disrupted the health system including human resources. Deployment of health workers during and after conflict raises many challenges for managers due to issues of security and staff shortage. We explored how deployment policies and practices were adapted during the conflict and post-conflict periods with the aim of drawing lessons for future responses to similar conflicts. Read More

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http://dx.doi.org/10.1186/s12960-019-0361-9DOI Listing

Simulation In Surgical Training: Prospective Cohort Study Of Access, Attitudes And Experiences Of Surgical Trainees In The Uk And Ireland.

Int J Surg 2019 Apr 14. Epub 2019 Apr 14.

Association of Surgeons in Training, 35-43 Lincoln's Inn Fields, London, WC2A 3PE.

Background: Surgical training is evolving, and simulation is becoming more important as a way to expedite the early learning curve and augment surgical techniques. With novel technology, and innovation, major changes are possible in how surgeons are trained. The integration of these concepts into the surgical curriculum may drive up educational standards and enhance patient safety. Read More

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http://dx.doi.org/10.1016/j.ijsu.2019.04.004DOI Listing

Guidelines for Postoperative care in Cesarean Delivery: Enhanced Recovery After Surgery (ERAS) Society Recommendations (Part 3 ).

Am J Obstet Gynecol 2019 Apr 14. Epub 2019 Apr 14.

Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, United States.

This Enhanced Recovery After Surgery (ERAS) Guideline for postoperative care in Cesarean Delivery (CD) will provide best practice, evidenced-based, recommendations for post-operative care with, primarily a maternal focus. The pathway process for scheduled and unscheduled CD, for this ERAS CD guideline, will consider time from completion of cesarean until maternal hospital discharge. The literature search (1966-2017) used Embase and PubMed to search medical subject headings including "Cesarean Section", "Cesarean Delivery", "Cesarean Section Delivery" and all post-operative ERAS® items. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193057
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http://dx.doi.org/10.1016/j.ajog.2019.04.012DOI Listing
April 2019
2 Reads

Psychometric validation of Anti-Clot Treatment Scale and Treatment Satisfaction Questionnaire for Medication version II in Japanese patients with atrial fibrillation.

J Med Econ 2019 Apr 17. Epub 2019 Apr 17.

i Modus Outcomes Ltd , Letchworth Garden City , UK.

Aims: The Anti-Clot Treatment Scale (ACTS) and Treatment Satisfaction Questionnaire for Medication version II (TSQM-II) are validated treatment satisfaction patient-reported outcome (PRO) instruments. The ACTS includes two domains: Burdens and Benefits; the TSQM-II includes four: Effectiveness, Side Effects, Convenience, and Global Satisfaction. Japanese-language versions of the ACTS and TSQM-II have been developed and linguistically validated. Read More

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http://dx.doi.org/10.1080/13696998.2019.1609003DOI Listing

Establishing Consensus on the Best Practice Guidelines for Use of Halo Gravity Traction for Pediatric Spinal Deformity.

J Pediatr Orthop 2019 Apr 15. Epub 2019 Apr 15.

Department of Orthopaedic Surgery, Columbia University Medical Center, New York.

Background: Although halo gravity traction (HGT) has been used to treat children with severe spinal deformity for decades, there is a distinct lack of high-quality evidence to speak to its merits or to dictate ideal manner of implementation. In addition, no guidelines exist to drive research or assist surgeons in their practice. The aim of this study was to establish best practice guidelines (BPG) using formal techniques of consensus building among a group of experienced pediatric spinal deformity surgeons to determine ideal indications and implementation of HGT for pediatric spinal deformity. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001379DOI Listing
April 2019
1 Read

Prevention of catheter-associated urinary tract infection in neurological post-operation patients: a best practice implementation project.

JBI Database System Rev Implement Rep 2019 Apr 15. Epub 2019 Apr 15.

Indiana Center for Evidence Based Nursing Practice: a Joanna Briggs Institute Affiliated Group.

Objective: The objective of this evidence based implementation project was to promote evidence based practice in the prevention of catheter-associated urinary tract infection (CAUTI) in the neurology and neurosurgery units of a Taipei hospital.

Introduction: Catheter-associated urinary tract infection has been associated with increased morbidity, mortality, hospital costs and length of stay. Urinary drainage systems are often reservoirs of infection in patients, thus effective prevention of CAUTI requires an evidence-based approach. Read More

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http://dx.doi.org/10.11124/JBISRIR-2017-003945DOI Listing
April 2019
1 Read

Anesthesia-administered sedation for endoscopic retrograde cholangiopancreatography: monitored anesthesia care or general endotracheal anesthesia?

Curr Opin Anaesthesiol 2019 Apr 15. Epub 2019 Apr 15.

Division of Gastroenterology, Washington University School of Medicine, Saint Louis, Missouri, USA.

Purpose Of Review: The decision to undertake monitored anesthesia care (MAC) or general endotracheal anesthesia (GEA) for patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) is influenced by many factors. These include locoregional practice preferences, procedure complexity, patient position, and comorbidities. We aim to review the data regarding anesthesia-administered sedation for ERCP and identify the impact of airway management on procedure success, adverse event rates and endoscopy unit efficiency. Read More

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http://dx.doi.org/10.1097/ACO.0000000000000741DOI Listing

[Archwire segmentation: a solution to the problems involved in treating atypical cases].

Orthod Fr 2019 Mar 17;90(1):65-74. Epub 2019 Apr 17.

56 rue des Tournelles, 75004 Paris, France.

Introduction: Asymmetrical orthodontic cases frequently prove very difficult to correct. Anchorage mini-screws are often needed to treat these cases when the malocclusion is of maxillary origin. Nonetheless, a precise biomechanical assessment must be made to avoid undesirable sideeffects resulting from the mechanics used. Read More

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https://www.orthodfr.org/10.1051/orthodfr/2019006
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http://dx.doi.org/10.1051/orthodfr/2019006DOI Listing
March 2019
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Do Community Treatment Orders in Psychiatry Stand Up to Principalism: Considerations Reflected through the Prism of the Convention on the Rights of Persons with Disabilities.

J Law Med Ethics 2019 Mar;47(1):126-133

Giles Newton-Howes, B.A., B.Sc., M.B.Ch.B., M.R.C.Psych., F.R.A.N.Z.C.P., PostDip.C.B.T., Ph.D., is an associate professor in the department of psychological medicine, University of Otago, Wellington. He is seconded to Te-Upoko-me-Te-Karuo-Te-Ika, the public health service that delivers mental health care to the lower part of the North Island of New Zealand, where he works as a consultant psychiatrist.

Compulsory psychiatric treatment is the norm in many Western countries, despite the increasingly individualistic and autonomous approach to medical interventions. Community Treatment Orders (CTOs) are the singular best example of this, requiring community patients to accept a variety of interventions, both pharmacological and social, despite their explicit wish not to do so. The epidemiological, medical/treatment and legal intricacies of CTOs have been examined in detail, however the ethical considerations are less commonly considered. Read More

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http://dx.doi.org/10.1177/1073110519840492DOI Listing

Be explicit: Defining the difference between the Office of Diversity & Inclusion and the Office of Diversity & Equity.

Med Teach 2019 Apr 17:1-2. Epub 2019 Apr 17.

a Hackensack Meridian School of Medicine , Seton Hall University , Kingsland St , Nutley , NJ , USA.

Diversity, inclusion, and equity are recognized as educational priorities and strategies for excellence across medical education. However, an inadvertent consequence of this push for best practice is that these terms are used interchangeably. This personal view intends to highlight the importance of language in an office of diversity and how it can potentially exacerbate the disparities it aims to alleviate. Read More

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http://dx.doi.org/10.1080/0142159X.2019.1597261DOI Listing

Predictors of dental care utilization in north-central Appalachia in the USA.

Community Dent Oral Epidemiol 2019 Apr 17. Epub 2019 Apr 17.

Center for Oral Health Research in Appalachia, University of Pittsburgh, Pittsburgh, Pennsylvania.

Objectives: Dental utilization is an important determinant of oral health and well-being. The aim of this study was to evaluate potential associations between a variety of biopsychosocial factors and dental utilization in north-central Appalachia, USA, a region where oral health disparities are profound.

Methods: This study used household-based data from the Center for Oral Health Research in Appalachia (COHRA1) study in north-central Appalachia, including 449 families with 868 adults. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cdoe.12453
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http://dx.doi.org/10.1111/cdoe.12453DOI Listing
April 2019
5 Reads

Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

Aging Clin Exp Res 2019 Apr 16. Epub 2019 Apr 16.

WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium.

There is increasing emphasis on patient-centred research to support the development, approval and reimbursement of health interventions that best meet patients' needs. However, there is currently little guidance on how meaningful patient engagement may be achieved. An expert working group, representing a wide range of stakeholders and disciplines, was convened by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the World Health Organization (WHO). Read More

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http://dx.doi.org/10.1007/s40520-019-01193-8DOI Listing

The human embryo, subjectivity and legal capacity. Notes in the light of art. 1 of the Italian law on "medically assisted procreation".

Clin Ter 2019 Mar-Apr;170(2):e102-e107

School of Law, University of Camerino.

Aim: This paper aims to examine the legal status of the human embryo taking into consideration Article 1 of the Italian law on medically assisted procreation, which protects the human embryo, which is recognised as an individual holding the same rights as already born children. The progressive increase in legal decisions regarding reproductive technologies requires a re-examination of the traditional legal categories of "subjectivity" and legal capacity, and a deeper understanding of the status of the human embryo as a subject, or individua.

Materials And Methods: The following sources were searched: Institutional websites, Research Centre for Social Investments reports, updated jurisprudence and Rulings of Italian Constitutional Court and European Court of Human Rights. Read More

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http://dx.doi.org/10.7417/CT.2019.2118DOI Listing
April 2019
2 Reads

MetaMSD: meta analysis for mass spectrometry data.

PeerJ 2019 10;7:e6699. Epub 2019 Apr 10.

School of Community Health Sciences, University of Nevada - Reno, Reno, NV, United States of America.

Mass spectrometry-based proteomics facilitate disease understanding by providing protein abundance information about disease progression. For the same type of disease studies, multiple mass spectrometry datasets may be generated. Integrating multiple mass spectrometry datasets can provide valuable information that a single dataset analysis cannot provide. Read More

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https://peerj.com/articles/6699
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http://dx.doi.org/10.7717/peerj.6699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462182PMC
April 2019
1 Read

Setting weights for fifteen CHNRI criteria at the global and regional level using public stakeholders: an Amazon Mechanical Turk study.

J Glob Health 2019 Jun;9(1):010702

Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

Introduction: Stakeholder involvement has been described as an indispensable part of health research priority setting. Yet, more than 75% of the exercises using the Child Health and Nutrition Research Initiative (CHNRI) methodology have omitted the step involving stakeholders in priority setting. Those that have used stakeholders have rarely used the public, possibly due to the difficulty of assembling and/or accessing a public stakeholder group. Read More

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http://dx.doi.org/10.7189/jogh.09.010702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445564PMC

What enables older people to continue with their falls prevention exercises? A qualitative systematic review.

BMJ Open 2019 Apr 15;9(4):e026074. Epub 2019 Apr 15.

RCN RI, Royal College of Nursing Research Institute, Warwick Medical School, University of Warwick, Coventry, UK.

Objectives: To review the qualitative literature that explores the barriers and facilitators to continued participation in falls prevention exercise after completion of a structured exercise programme.

Design: A systematic literature review with thematic synthesis of qualitative studies exploring older adults' experiences of continued participation in falls prevention exercise.

Data Sources: Comprehensive searches were conducted in MEDLINE, PSYCHinfo, AMED, ASSIA, CINAHL and EMBASE from inception until November 2017. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026074DOI Listing

Estimation of early life endogenous surfactant pool and CPAP failure in preterm neonates with RDS.

Respir Res 2019 Apr 16;20(1):75. Epub 2019 Apr 16.

Division of Pediatrics and Neonatal Critical Care, Medical Center "A.Béclère", South Paris University Hospitals, AP-HP, Paris, France.

Background: It is not known if the endogenous surfactant pool available early in life is associated with the RDS clinical course in preterm neonates treated with CPAP. We aim to clarify the clinical factors affecting surfactant pool in preterm neonates and study its association with CPAP failure.

Methods: Prospective, pragmatic, blind, cohort study. Read More

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http://dx.doi.org/10.1186/s12931-019-1040-zDOI Listing

A mixed-methods approach to understanding partnership experiences and outcomes of projects from an integrated knowledge translation funding model in rehabilitation.

BMC Health Serv Res 2019 Apr 16;19(1):230. Epub 2019 Apr 16.

School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada.

Background: Integrated knowledge translation (IKT) can optimize the uptake of research evidence into clinical practice by incorporating knowledge users as equal partners in the entire research process. Although several studies have investigated stakeholder involvement in research, the literature on partnerships between researchers and clinicians in rehabilitation and their impact on clinical practice is scarce. This study described the individual research projects, the outcomes of these projects on clinical practice and the partnership experiences of an initiative that funds IKT projects co-led by a rehabilitation clinician and a researcher. Read More

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https://bmchealthservres.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12913-019-4061-xDOI Listing
April 2019
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Medical education today: all that glitters is not gold.

BMC Med Educ 2019 Apr 16;19(1):110. Epub 2019 Apr 16.

Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), 6431 Fannin St., MSB2.276, Houston, TX, 77005, USA.

Background: The medical education system based on principles advocated by Flexner and Osler has produced generations of scientifically grounded and clinically skilled physicians whose collective experiences and contributions have served medicine and patients well. Yet sweeping changes launched around the turn of the millennium have constituted a revolution in medical education. In this article, a critique is presented of the new undergraduate medical education (UME) curricula in relationship to graduate medical education (GME) and clinical practice. Read More

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https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909
Publisher Site
http://dx.doi.org/10.1186/s12909-019-1535-9DOI Listing
April 2019
1 Read

The current evidence-based management of distal radial fractures: UK perspectives.

J Hand Surg Eur Vol 2019 Apr 16:1753193419843201. Epub 2019 Apr 16.

1 Academic Team of Musculoskeletal Surgery, Leicester General Hospital, Leicester, UK.

Distal radial fractures are extremely common injuries, yet many basic questions remain unanswered about their optimum management. Recently in the United Kingdom several guideline development groups have produced national standards and best-practice guidelines based on review of the best available evidence and expert knowledge. All guideline groups agree that when surgery is needed for dorsally displaced distal radial fractures, that can be reduced closed, K-wire fixation and cast immobilization, should be offered. Read More

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http://dx.doi.org/10.1177/1753193419843201DOI Listing

Effects of the amount of practice and time interval between practice sessions on the retention of internal models.

PLoS One 2019 16;14(4):e0215331. Epub 2019 Apr 16.

School of Humanities and Social Sciences, Waseda University, Tokyo, Japan.

The amount of practice and time interval between practice sessions are important factors that influence motor learning efficiency. Here, we aimed to reveal the relationship between the retention and consolidation of a new internal model, and the amount of practice and time interval between practice sessions. We employed a visuomotor rotation tracking task to test the hypotheses that (1) a new internal model consolidates owing to extensive practice after reaching a task performance plateau and (2) a longer time interval between practice sessions makes it difficult to activate a new internal model. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215331PLOS
April 2019
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Reverse Educational Distance: Exploring a novel concept to enhance Resident-As-Teacher curricula.

Med Teach 2019 Apr 16:1-7. Epub 2019 Apr 16.

b Centre for Medical Education, Faculty of Medicine , McGill University , Montreal , Canada.

Purpose: The learning benefits associated with residents teaching peers and junior trainees are well documented. However, the concept of Reverse Educational Distance (RED), when residents teach an academically senior audience, is poorly described.

Methods: We explored Pediatric residents' and community health care providers' (cHCPs) perceptions of a RED teaching intervention, whereby residents would engage in teaching cHCPs. Read More

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https://www.tandfonline.com/doi/full/10.1080/0142159X.2019.1
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http://dx.doi.org/10.1080/0142159X.2019.1578875DOI Listing
April 2019
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Supporting Data vs Patient Requests in Oncology: When the Two Don't Coincide.

Oncology (Williston Park) 2019 04;33(4):156-8

Relationships between cancer patients and their oncologists flourish in a milieu of trust and goodwill. However, at times cancer patients may express strong preferences for medical tests, treatments, or other interventions that are not beneficial. Actively challenging these requests can be difficult and may threaten the patient-physician relationship. Read More

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April 2019
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Child Passenger Safety: AAP Updates Best Practice Recommendations.

Authors:
Jennifer Wilkes

Am Fam Physician 2019 Apr;99(8):525-526

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The human risks of bias in medical and rehabilitation research and practice: the 8 I's.

Authors:
Antti Malmivaara

Eur J Phys Rehabil Med 2019 Apr 15. Epub 2019 Apr 15.

Centre for Health and Social Economics, National Institute for Health and Welfare Mannerheimintie, Helsinki, Finland -

Background: The human mind is liable to make biased interpretations. The biomedical paradigm supposes that an objective truth can be reached with rigorous scientific methods. Human risk of bias is defined in this paper as threats to validity of study results that cannot be controlled even by rigorous scientific methods. Read More

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http://dx.doi.org/10.23736/S1973-9087.19.05807-6DOI Listing

Neoadjuvant Chemotherapy in Non-Metastatic Breast Cancer- A Study on Practice Trends in a Regional Cancer Treatment Service.

Intern Med J 2019 Apr 16. Epub 2019 Apr 16.

Medical Oncology, Palmerston North Hospital, New Zealand.

Aims: Neoadjuvant Chemotherapy (NACT) is increasingly used for managing locally advanced and high risk non-metastatic breast cancer(NMBC). The goal of this study is to describe trends in NACT use, assess compliance to best practice recommendations and determine treatment response rates in a regional cancer treatment service.

Method: In this retrospective cross- sectional study, electronic records of patients who underwent NACT in centres covered by the Midcentral Regional Cancer Treatment Service (RCTS) in 2013 and 2017 were reviewed. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/imj.14326
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http://dx.doi.org/10.1111/imj.14326DOI Listing
April 2019
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Virtual Care 2.0-a Vision for the Future of Data-Driven Technology-Enabled Healthcare.

Curr Treat Options Cardiovasc Med 2019 Apr 15;21(5):21. Epub 2019 Apr 15.

Department of Medicine, Divisions of General Internal Medicine and Biomedical Informatics, Chief Medical Information Officer of Population Health, University of California San Diego, 9560 Towne Centre Drive, San Diego, CA, 92121, USA.

A busy community cardiologist finished reading eight echocardiograms over lunch and started clinic at 1 pm. As three patients waited, "Jane," a 45-year-old graphic designer was seen for "skipped heart beat." She works about 50 h a week, exercises at the local gym, and enjoys eating a healthy diet. Read More

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http://link.springer.com/10.1007/s11936-019-0727-2
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http://dx.doi.org/10.1007/s11936-019-0727-2DOI Listing
April 2019
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Pharmacy student professional identity formation: a scoping review.

Integr Pharm Res Pract 2019 27;8:15-34. Epub 2019 Mar 27.

School of Pharmacy, The University of Queensland, Woolloongabba, QLD, Australia,

Purpose: Transitioning from being pharmacy students to pharmacists is challenging. Students need to reconcile their professional aspirations and what they have learnt with the realities of practice. A smooth transition can be hampered when they are unable to enact the role they have envisaged or if their expectations are not met. Read More

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https://www.dovepress.com/pharmacy-student-professional-iden
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http://dx.doi.org/10.2147/IPRP.S162799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443221PMC
March 2019
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A retrospective observational analysis of red blood cell transfusion practices in stable, non-bleeding adult patients admitted to nine medical-surgical intensive care units.

J Intensive Care 2019 4;7:19. Epub 2019 Apr 4.

1Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, 3D18, Teaching Research and Wellness Building, 3280 Hospital Drive NW, Calgary, Alberta T2N 4N1 Canada.

Background: Red blood cell (RBC) transfusions are common procedures performed in the intensive care unit (ICU). However, conservative transfusion approaches have been recommended to avoid RBC transfusions that are not clinically necessary and to achieve optimal patient outcomes. The objective of this study was to examine the utilization and costs of RBC transfusions in medical-surgical ICUs and to compare this information against clinical guideline recommendations for best practice. Read More

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http://dx.doi.org/10.1186/s40560-019-0375-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449900PMC