J Occup Environ Med 2020 01;62(1):64-73
Department of Public Health and Preventive Medicine, Universitas Sebelas Maret, Surakarta, Indonesia (Dr Widyaningsih); Department of Medicine (Dr Rosenman, Ms Reilly, Dr Wang); Department of Epidemiology and Biostatistics (Dr Pathak, Dr Gardiner), Michigan State University, East Lansing, Michigan; Department of Environmental Health, University of Cincinnati, Cincinnati (Dr Rice); Department of Pathology and Laboratory Medicine (Dr Monos); Department of Medicine (Dr Rossman), University of Pennsylvania, Philadelphia.
Objective: To evaluate interaction of HLA-DPβ1 and DRβ1 polymorphisms with metrics of beryllium exposure, in the development of beryllium sensitization (BeS) and chronic beryllium disease (CBD).
Methods: A matched case-control study of 61 CBD, 41 BeS, and 259 controls from two beryllium-processing facilities.
Results: BES and CBD were significantly associated with presence of DPβE69. Read More