1,606 results match your criteria Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability[Journal]


Estimating lifetime malnourished period and its statistics based on the concept of Markov chain with reward.

Heliyon 2020 May 28;6(5):e04073. Epub 2020 May 28.

Department of Statistics, Federal University of Technology, Akure, Nigeria.

Malnutrition among women, accessed through body mass index, has great consequences for achieving key national targets. This study introduces the concept of lifetime malnourished period (LMP): the number of years a woman would remain malnourished, either as underweight or overweight given that she is currently malnourished, and its measures of variation. Markov chain with rewards was used to compute the moments of LMP based on age-specific mortality rates and proportion of women of reproductive age that were either underweight or overweight using data from the 2013 Nigeria Demographic and Health Survey. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262447PMC

Spatiotemporal analyses of foot and mouth disease outbreaks in cattle farms in Chiang Mai and Lamphun, Thailand.

BMC Vet Res 2020 Jun 1;16(1):170. Epub 2020 Jun 1.

Veterinary Public Health Centre for Asia Pacific and Excellent Center for Veterinary Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, Thailand.

Background: Foot and mouth disease (FMD) is a highly infectious and contagious febrile vesicular disease of cloven-hoofed livestock with high socio-economic consequences globally. In Thailand, FMD is endemic with 183 and 262 outbreaks occurring in the years 2015 and 2016, respectively. In this study, we aimed to assess the spatiotemporal distribution of FMD outbreaks among cattle in Chiang Mai and Lamphun provinces in the northern part of Thailand during the period of 2015-2016. Read More

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http://dx.doi.org/10.1186/s12917-020-02392-6DOI Listing

Narrowed Posterior Nasal Airway Limits Efficacy of Anterior Septoplasty.

Facial Plast Surg Aesthet Med 2020 May 29. Epub 2020 May 29.

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Predicting symptomatic relief after septoplasty has been difficult. Minimal cross-sectional area (mCSA) measured by acoustic rhinometry and airflow resistance () measured by rhinomanometry have been used to select surgical candidates with mixed success. An important assumption is that mCSA and resistance are tightly coupled, but studies have reported weak or no correlation. Read More

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http://dx.doi.org/10.1089/fpsam.2020.0081DOI Listing

Use of an Extended Premise Condition Index for detection of priority areas for vector control actions.

Acta Trop 2020 May 26:105543. Epub 2020 May 26.

Faculdade de Saúde Pública, Universidade de São Paulo. Avenida Doutor Arnaldo, 715, São Paulo, SP, Brazil, 01246-904. Electronic address:

The Premise Condition Index (PCI), proposed by Tun-Lin and colleagues in 1995, is a score that considers the conditions of a premise as well its yards and degree of shading. They hypothesized that the higher its value the greater the probability of the premise having the presence of Aedes aegypti. This study aimed to evaluate if there is a correspondence between PCI and Ae. Read More

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http://dx.doi.org/10.1016/j.actatropica.2020.105543DOI Listing

Towards improving the accuracy of aortic transvalvular pressure gradients: rethinking Bernoulli.

Med Biol Eng Comput 2020 May 26. Epub 2020 May 26.

Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine, Charité Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

The transvalvular pressure gradient (TPG) is commonly estimated using the Bernoulli equation. However, the method is known to be inaccurate. Therefore, an adjusted Bernoulli model for accurate TPG assessment was developed and evaluated. Read More

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http://dx.doi.org/10.1007/s11517-020-02186-wDOI Listing

Supervised Mixture of Experts Models for Population Health.

Methods 2020 May 21. Epub 2020 May 21.

Institute for Data Exploration and Applications, Rensselaer Polytechnic Institute, Troy, USA; Mathematics Department, Rensselaer Polytechnic Institute, Troy, USA; Computer Science Department, Rensselaer Polytechnic Institute, Troy, USA.

We propose a machine learning driven approach to derive insights from observational healthcare data to improve public health outcomes. Our goal is to simultaneously identify patient subpopulations with differing health risks and to find those risk factors within each subpopulation. We develop two supervised mixture of experts models: a Supervised Gaussian Mixture model (SGMM) for general features and a Supervised Bernoulli Mixture model (SBMM) tailored to binary features. Read More

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http://dx.doi.org/10.1016/j.ymeth.2020.05.016DOI Listing

A characterisation of the reconstructed birth-death process through time rescaling.

Theor Popul Biol 2020 May 18;134:61-76. Epub 2020 May 18.

Department of Statistics, University of Warwick, Coventry CV4 7AL, UK; Department of Computer Science, University of Warwick, Coventry CV4 7AL, UK; The Alan Turing Institute, British Library, London NW1 2DB, UK.

The dynamics of a population exhibiting exponential growth can be modelled as a birth-death process, which naturally captures the stochastic variation in population size over time. In this article, we consider a supercritical birth-death process, started at a random time in the past, and conditioned to have n sampled individuals at the present. The genealogy of individuals sampled at the present time is then described by the reversed reconstructed process (RRP), which traces the ancestry of the sample backwards from the present. Read More

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http://dx.doi.org/10.1016/j.tpb.2020.05.001DOI Listing

Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area.

Rev Soc Bras Med Trop 2020 18;53:e20190525. Epub 2020 May 18.

Departamento de Produção e Saúde Animal, Faculdade de Medicina Veterinária, Universidade Estadual Paulista, Araçatuba, SP, Brasil.

Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. Read More

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http://dx.doi.org/10.1590/0037-8682-0525-2019DOI Listing

A curtailed selection procedure for comparing Bernoulli outcomes with a control.

J Biopharm Stat 2020 May 14:1-11. Epub 2020 May 14.

Department of Mathematics, Le Moyne College, Syracuse, NY, USA.

A sequential selection procedure is proposed for comparing [Formula: see text] experimental Bernoulli populations with a controlled Bernoulli population. The comparison is made according to the success probability. Based on the numbers of successes of the [Formula: see text] populations, the indifference zone formulation and the subset selection formulation are integrated to select either the best population or a random-sized subset that contains the best population. Read More

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http://dx.doi.org/10.1080/10543406.2020.1765369DOI Listing

Prospective monitoring of imaging guideline adherence by physicians in a surgical collaborative: comparison of statistical process control methods for detecting outlying performance.

BMC Med Inform Decis Mak 2020 May 13;20(1):89. Epub 2020 May 13.

Department of Urology, University of Michigan, NCRC Bldg. 16, 1st Floor, Room 114W, 2800 Plymouth Road, Ann Arbor, MI, 48109-2900, USA.

Background: Systematic, automated methods for monitoring physician performance are necessary if outlying behavior is to be detected promptly and acted on. In the Michigan Urological Surgery Improvement Collaborative (MUSIC), we evaluated several statistical process control (SPC) methods to determine the sensitivity and ease of interpretation for assessing adherence to imaging guidelines for patients with newly diagnosed prostate cancer.

Methods: Following dissemination of imaging guidelines within the Michigan Urological Surgery Improvement Collaborative (MUSIC) for men with newly diagnosed prostate cancer, MUSIC set a target of imaging < 10% of patients for which bone scan is not indicated. Read More

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http://dx.doi.org/10.1186/s12911-020-1126-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218839PMC

Compressive Sensing Approach to Harmonics Detection in the Ship Electrical Network.

Sensors (Basel) 2020 May 11;20(9). Epub 2020 May 11.

Department of Marine Electrical Power Engineering, Gdynia Maritime University, Morska 81-87, 81-225 Gdynia, Poland.

The contribution of this paper is to show the opportunities for using the compressive sensing (CS) technique for detecting harmonics in a frequency sparse signal. The signal in a ship's electrical network, polluted by harmonic distortions, can be modeled as a superposition of a small number of sinusoids and the discrete Fourier transform (DFT) basis forms its sparse domain. According to the theory of CS, a signal may be reconstructed from under-sampled incoherent linear measurements. Read More

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http://dx.doi.org/10.3390/s20092744DOI Listing

Spatial Distribution and Factors Associated with Khat Chewing among Adult Males 15-59 Years in Ethiopia Using a Secondary Analysis of Ethiopian Demographic and Health Survey 2016: Spatial and Multilevel Analysis.

Psychiatry J 2020 20;2020:8369693. Epub 2020 Apr 20.

Department of Psychiatry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Background: Khat chewing has become prevalent in the world due to the improvement of road and air transportation. In Ethiopia, khat chewing is more prevalent and widely practiced by men. Khat has a negative effect on social, economic, and mental health. Read More

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http://dx.doi.org/10.1155/2020/8369693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191385PMC

Homogenization and Equivalent Beam Model for Fiber-Reinforced Tubular Profiles.

Materials (Basel) 2020 Apr 30;13(9). Epub 2020 Apr 30.

DICAM Department, University of Bologna, 40136 Bologna, Italy.

The current work presents a study on hollow cylinder composite beams, since hollow cylinder cross-sections are one of the principal geometry in many engineering fields. In particular, the present study considers the use of these profiles for scaffold design in offshore engineering. Composite beams cannot be treated as isotropic ones due to couplings mainly present among traction, torsion, bending and shear coefficients. Read More

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http://dx.doi.org/10.3390/ma13092069DOI Listing

Hemodynamic principles of prosthetic aortic valve evaluation in the transcatheter aortic valve replacement era.

Echocardiography 2020 May 3;37(5):738-757. Epub 2020 May 3.

Laval University, Quebec, QC, Canada.

Evaluating the hemodynamic performance of aortic valve prostheses has relied primarily on echocardiography. This involves calculating the trans-prosthetic valve mean gradient (MG) and aortic valve area (AVA), and assessing for valvular and paravalvular regurgitation in a fashion similar to the native aortic valve. In conjunction with other echocardiographic and nonechocardiographic parameters, MG and AVA are used to distinguish between prosthesis stenosis, prosthesis patient mismatch, pressure recovery, increased flow, and measurement errors. Read More

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http://dx.doi.org/10.1111/echo.14663DOI Listing

An improved gray Bernoulli model for estimating the relationship between economic growth and pollution emissions.

Environ Sci Pollut Res Int 2020 Apr 30. Epub 2020 Apr 30.

School of Economics, Zhejiang University of Finance & Economics, Hangzhou, 310018, China.

The environmental Kuznets curve (EKC) hypothesis is used to describe the relationship between economic development and environmental pollution. In this paper, an EKC-estimating method based on an improved nonlinear gray Bernoulli model (NGBM) is proposed from the perspective of gray system modeling. First, a non-equigap NGBM is established taking the GDP per capita and pollutant emission as the input and output of the gray system, respectively. Read More

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http://dx.doi.org/10.1007/s11356-020-08951-6DOI Listing

The geometry of multi-marginal Skorokhod Embedding.

Probab Theory Relat Fields 2020 1;176(3):1045-1096. Epub 2019 Aug 1.

1Universität Wien, Vienna, Austria.

The Skorokhod Embedding Problem is one of the classical problems in the theory of stochastic processes, with applications in many different fields [cf.  the surveys (Hobson in: Paris-Princeton lectures on mathematical finance 2010, Volume 2003 of Lecture Notes in Mathematics, Springer, Berlin, 2011; Obłój in: Probab Surv 1:321-390, 2004)]. Many of these applications have natural multi-marginal extensions leading to the . Read More

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http://dx.doi.org/10.1007/s00440-019-00935-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175629PMC

Statistics in Proteomics: A Meta-analysis of 100 Proteomics Papers Published in 2019.

J Am Soc Mass Spectrom 2020 May 1. Epub 2020 May 1.

Department of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW 2109, Australia.

We randomly selected 100 journal articles published in five proteomics journals in 2019 and manually examined each of them against a set of 13 criteria concerning the statistical analyses used, all of which were based on items mentioned in the journals' instructions to authors. This included questions such as whether a pilot study was conducted and whether false discovery rate calculation was employed at either the quantitation or identification stage. These data were then transformed to binary inputs, analyzed via machine learning algorithms, and classified accordingly, with the aim of determining if clusters of data existed for specific journals or if certain statistical measures correlated with each other. Read More

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http://dx.doi.org/10.1021/jasms.9b00142DOI Listing

Efficient and Effective Context-Based Convolutional Entropy Modeling for Image Compression.

IEEE Trans Image Process 2020 Apr 14. Epub 2020 Apr 14.

Precise estimation of the probabilistic structure of natural images plays an essential role in image compression. Despite the recent remarkable success of end-to-end optimized image compression, the latent codes are usually assumed to be fully statistically factorized in order to simplify entropy modeling. However, this assumption generally does not hold true and may hinder compression performance. Read More

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http://dx.doi.org/10.1109/TIP.2020.2985225DOI Listing

Studying the spatial temporal spread of the citrus tristeza virus through ODEs and Bernoulli trials.

J Theor Biol 2020 Jul 13;497:110279. Epub 2020 Apr 13.

United States Sugar Corporation, Clewiston, Florida, United States.

The Citrus tristeza virus (CTV) is one of the most economically devastating citrus diseases worldwide. The spread of CTV in eastern Spain was studied by Gottwald et al. with the goal of determining the spatio-temporal mechanisms of spread. Read More

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http://dx.doi.org/10.1016/j.jtbi.2020.110279DOI Listing

Experimental and theoretical studies of frequency response function of dagger-shaped atomic force microscope cantilever in different immersion environments.

J Microsc 2020 Apr 13. Epub 2020 Apr 13.

Renewable Energy Research Center, Damavand Branch, Islamic Azad University, Damavand, Iran.

In this study, the amplitude of frequency response functions of vertical and rotational displacements and resonant frequency of a dagger-shaped atomic force microscope cantilever have been investigated. To increase the accuracy of theoretical model, all necessary details for cantilever and sample surface have been taken into account. In this paper, carbon tetrachloride (CCL ), methanol, acetone, water and air have been considered as the environments. Read More

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http://dx.doi.org/10.1111/jmi.12897DOI Listing

Effects of Multi-Point Contacts during Object Contour Scanning Using a Biologically-Inspired Tactile Sensor.

Sensors (Basel) 2020 Apr 7;20(7). Epub 2020 Apr 7.

Faculty of Mechanical Engineering, Schmalkalden University of Applied Sciences, 98574 Schmalkalden, Germany.

Vibrissae are an important tactile sense organ of many mammals, in particular rodents like rats and mice. For instance, these animals use them in order to detect different object features, e.g. Read More

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http://dx.doi.org/10.3390/s20072077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180713PMC

EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications.

Epigenetics Chromatin 2020 Apr 7;13(1):20. Epub 2020 Apr 7.

Institute for Medical Bioinformatics and Biostatistics, Philipps University of Marburg, 35037, Marburg, Germany.

Background: Understanding the transcriptome is critical for explaining the functional as well as regulatory roles of genomic regions. Current methods for the identification of transcription units (TUs) use RNA-seq that, however, require large quantities of mRNA rendering the identification of inherently unstable TUs, e.g. Read More

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http://dx.doi.org/10.1186/s13072-020-00341-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137282PMC

A practical proposal to obtain solutions of certain variational problems avoiding Euler formalism.

Heliyon 2020 Apr 1;6(4):e03703. Epub 2020 Apr 1.

Escuela de Ingeniería, Universidad de Xalapa, Km 2, Carr. Xalapa-Veracruz 341, 91190 Xalapa, Veracruz, Mexico.

The aim of this article is to show the way to get both, exact and analytical approximate solutions for certain variational problems with moving boundaries but without resorting to Euler formalism at all, for which we propose two methods: the Moving Boundary Conditions Without Employing Transversality Conditions (MWTC) and the Moving Boundary Condition Employing Transversality Conditions (METC). It is worthwhile to mention that the first of them avoids the concept of transversality condition, which is basic for this kind of problems, from the point of view of the known Euler formalism. While it is true that the second method will utilize the above mentioned conditions, it will do through a systematic elementary procedure, easy to apply and recall; in addition, it will be seen that the Generalized Bernoulli Method (GBM) will turn out to be a fundamental tool in order to achieve these objectives. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118316PMC

Clb3-centered regulations are recurrent across distinct parameter regions in minimal autonomous cell cycle oscillator designs.

NPJ Syst Biol Appl 2020 Apr 3;6(1). Epub 2020 Apr 3.

Systems Biology, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.

Some biological networks exhibit oscillations in their components to convert stimuli to time-dependent responses. The eukaryotic cell cycle is such a case, being governed by waves of cyclin-dependent kinase (cyclin/Cdk) activities that rise and fall with specific timing and guarantee its timely occurrence. Disruption of cyclin/Cdk oscillations could result in dysfunction through reduced cell division. Read More

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http://dx.doi.org/10.1038/s41540-020-0125-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125140PMC

Distributed Robust Filtering for Wireless Sensor Networks with Markov Switching Topologies and Deception Attacks.

Sensors (Basel) 2020 Mar 31;20(7). Epub 2020 Mar 31.

Engineering Research Center of Internet of Things Applied Technology, Jiangnan University, Ministry of Education, Wuxi 214122, Jiangsu, China.

This paper is concerned with the distributed full- and reduced-order l 2 - l ∞ state estimation issue for a class of discrete time-invariant systems subjected to both randomly occurring switching topologies and deception attacks over wireless sensor networks. Firstly, a switching topology model is proposed which uses homogeneous Markov chain to reflect the change of filtering networks communication modes. Then, the sector-bound deception attacks among the communication channels are taken into consideration, which could better characterize the filtering network communication security. Read More

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http://dx.doi.org/10.3390/s20071948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181283PMC

Interfacial adhesion of ZnO nanowires on a Si substrate in air.

Nanoscale 2020 Apr 1;12(15):8237-8247. Epub 2020 Apr 1.

School of Mechanical and Mining Engineering, The University of Queensland, QLD 4072, Australia.

It is imperative to understand the interfacial adhesive behaviour of nanowires (NW) integrated into a nanoelectromechanical system in order to design commercialisable nanogenerators as well as ultrasensitive sensors. Currently available interfacial adhesion characterisation techniques that utilise in situ electron microscopy subject nanoscale systems to a high-vacuum, electron-irradiated environment, potentially altering their interfacial interactions. Alternatively, force-sensing techniques conducted in air do not provide visual feedback of the interface, and therefore can only indirectly deduce adhesive properties. Read More

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http://dx.doi.org/10.1039/d0nr01261kDOI Listing

Heart rate variability as a measure of mental stress in surgery: a systematic review.

Int Arch Occup Environ Health 2020 Mar 25. Epub 2020 Mar 25.

Department of Artificial Intelligence, Bernoulli Institute of Mathematics, Computer Science and Artificial Intelligence, Faculty of Science and Engineering, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.

Purpose: There is increasing interest in the use of heart rate variability (HRV) as an objective measurement of mental stress in the surgical setting. To identify areas of improvement, the aim of our study was to review current use of HRV measurements in the surgical setting, evaluate the different methods used for the analysis of HRV, and to assess whether HRV is being measured correctly.

Methods: A systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). Read More

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http://dx.doi.org/10.1007/s00420-020-01525-6DOI Listing

A Modified Couple Stress Elasticity for Non-Uniform Composite Laminated Beams Based on the Ritz Formulation.

Molecules 2020 Mar 19;25(6). Epub 2020 Mar 19.

Department of Innovation Engineering, Università del Salento, 73100 Lecce, Italy.

Due to the large application of tapered beams in smart devices, such as scanning tunneling microscopes (STM), nano/micro electromechanical systems (NEMS/MEMS), atomic force microscopes (AFM), as well as in military aircraft applications, this study deals with the vibration behavior of laminated composite non-uniform nanobeams subjected to different boundary conditions. The micro-structural size-dependent free vibration response of composite laminated Euler-Bernoulli beams is here analyzed based on a modified couple stress elasticity, which accounts for the presence of a length scale parameter. The governing equations and boundary conditions of the problem are developed using the Hamilton's principle, and solved by means of the Rayleigh-Ritz method. Read More

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http://dx.doi.org/10.3390/molecules25061404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144387PMC

PPanGGOLiN: Depicting microbial diversity via a partitioned pangenome graph.

PLoS Comput Biol 2020 Mar 19;16(3):e1007732. Epub 2020 Mar 19.

LABGeM, Génomique Métabolique, CEA, Genoscope, Institut François Jacob, Université d'Évry, Université Paris-Saclay, CNRS, Evry, France.

The use of comparative genomics for functional, evolutionary, and epidemiological studies requires methods to classify gene families in terms of occurrence in a given species. These methods usually lack multivariate statistical models to infer the partitions and the optimal number of classes and don't account for genome organization. We introduce a graph structure to model pangenomes in which nodes represent gene families and edges represent genomic neighborhood. Read More

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http://dx.doi.org/10.1371/journal.pcbi.1007732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108747PMC

Spatial distribution and associated factors of health insurance coverage in Ethiopia: further analysis of Ethiopia demographic and health survey, 2016.

Arch Public Health 2020 16;78:25. Epub 2020 Mar 16.

3Department of Physiology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Health insurance is one of the instruments to achieve universal health coverage. However, in Ethiopia, the coverage of health insurance is very low and varies from place to place as well. Therefore, exploring the spatial distribution of health insurance is important to prioritize and design targeted intervention programs in the country. Read More

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http://dx.doi.org/10.1186/s13690-020-00407-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076975PMC

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report.

Blood 2020 May;135(20):1759-1771

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.

Based on the profile of genetic alterations occurring in tumor samples from selected diffuse large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies proposed partially overlapping classification systems. Using clustering techniques applied to targeted sequencing data derived from a large unselected population-based patient cohort with full clinical follow-up (n = 928), we investigated whether molecular subtypes can be robustly identified using methods potentially applicable in routine clinical practice. DNA extracted from DLBCL tumors diagnosed in patients residing in a catchment population of ∼4 million (14 centers) were sequenced with a targeted 293-gene hematological-malignancy panel. Read More

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http://dx.doi.org/10.1182/blood.2019003535DOI Listing

ccbmlib - a Python package for modeling Tanimoto similarity value distributions.

F1000Res 2020 10;9. Epub 2020 Feb 10.

Department of Life Science Informatics, B-IT, University of Bonn, Endenicher Allee 19c, Bonn, NRW, 53115, Germany.

The ccbmlib Python package is a collection of modules for modeling similarity value distributions based on Tanimoto coefficients for fingerprints available in RDKit. It can be used to assess the statistical significance of Tanimoto coefficients and evaluate how molecular similarity is reflected when different fingerprint representations are used. Significance measures derived from -values allow a quantitative comparison of similarity scores obtained from different fingerprint representations that might have very different value ranges. Read More

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http://dx.doi.org/10.12688/f1000research.22292.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050271.2PMC
February 2020

Reduction of oscillator dynamics on complex networks to dynamics on complete graphs through virtual frequencies.

Phys Rev E 2020 Feb;101(2-1):022302

Division of Natural and Applied Sciences and Zu Chongzhi Center for Mathematics and Computational Science, Duke Kunshan University, No. 8 Duke Avenue, Kunshan 215316, China.

We consider the synchronization of oscillators in complex networks where there is an interplay between the oscillator dynamics and the network topology. Through a remarkable transformation in parameter space and the introduction of virtual frequencies we show that Kuramoto oscillators on annealed networks, with or without frequency-degree correlation, and Kuramoto oscillators on complete graphs with frequency-weighted coupling can be transformed to Kuramoto oscillators on complete graphs with a rearranged, virtual frequency distribution and uniform coupling. The virtual frequency distribution encodes both the natural frequency distribution (dynamics) and the degree distribution (topology). Read More

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http://dx.doi.org/10.1103/PhysRevE.101.022302DOI Listing
February 2020

Nonclassical dynamic modeling of nano/microparticles during nanomanipulation processes.

Beilstein J Nanotechnol 2020 13;11:147-166. Epub 2020 Jan 13.

Robotic Research Laboratory, Center of Excellence in Experimental Solid Mechanics and Dynamics, School of Mechanical Engineering, Iran University of Science and Technology, Narmak, Tehran, Iran.

Since the manipulation of particles using atomic force microscopy is not observable in real-time, modeling the manipulation process is of notable importance, enabling us to investigate the dynamical behavior of nanoparticles. To model this process, previous studies employed classical continuum mechanics and molecular dynamics simulations which had certain limitations; the former does not consider size effects at the nanoscale while the latter is time consuming and faces computational restrictions. To optimize accuracy and computational costs, a new nonclassical modeling of the nanomanipulation process based on the modified couple stress theory is proposed that includes the size effects. Read More

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http://dx.doi.org/10.3762/bjnano.11.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006494PMC
January 2020

Tracing the Origin of Food-borne Disease Outbreaks: A Network Model Approach.

Epidemiology 2020 May;31(3):327-333

Department of Statistics, Informatics and Modelling, National Institute for Public Health and the Environment, Bilthoven, Netherlands.

Background: Food-borne disease outbreaks constitute a large health burden on society. One of the challenges when investigating such outbreaks is to trace the origin of the outbreak. In this study, we consider a network model to determine the spatial origin of the contaminated food product that caused the outbreak. Read More

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http://dx.doi.org/10.1097/EDE.0000000000001169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144751PMC

LCBM: A Multi-view Probabilistic Model for Multi-label Classification.

IEEE Trans Pattern Anal Mach Intell 2020 Feb 17. Epub 2020 Feb 17.

Multi-label classification is an important research topic in machine learning, for which exploiting label dependency is an effective modeling principle. Recently, probabilistic models have shown great potential in discovering dependencies among labels. In this paper, motivated by the recent success of multi-view learning to improve the generalization performance, we propose a novel multi-view probabilistic model named latent conditional Bernoulli mixture (LCBM) for multi-label classification. Read More

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http://dx.doi.org/10.1109/TPAMI.2020.2974203DOI Listing
February 2020

Automated Parameter Extraction Of ScAlN MEMS Devices Using An Extended Euler-Bernoulli Beam Theory.

Sensors (Basel) 2020 Feb 13;20(4). Epub 2020 Feb 13.

Advanced Electromagnetics Group, Department of Electrical Engineering and Information Technology, Technische Universität Ilmenau, Postfach 100565, 98684 Ilmenau, Germany.

Magnetoelectric sensors provide the ability to measure magnetic fields down to the pico tesla range and are currently the subject of intense research. Such sensors usually combine a piezoelectric and a magnetostrictive material, so that magnetically induced stresses can be measured electrically. Scandium aluminium nitride gained a lot of attraction in the last few years due to its enhanced piezoelectric properties. Read More

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http://dx.doi.org/10.3390/s20041001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071012PMC
February 2020

Investigations on the buckling and dynamics of diving-inspired systems when entering water.

Bioinspir Biomim 2020 Mar 31;15(3):036015. Epub 2020 Mar 31.

Department of Mechanical and Aerospace Engineering, New Mexico State University, Las Cruces, NM 88003, United States of America.

This work provides comparative modeling approaches to determine the velocities and natural frequencies of plunge-diving bird and bioinspired drone systems when entering water. These systems are chosen to further explain the survival of diving birds as they impact water and to provide insight into the design geometry and material choice of bioinspired diving drones. A nonlinear reduced-order model is developed and utilized to analyze the dive at impact considering both Timoshenko and Euler-Bernoulli beam theories. Read More

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http://dx.doi.org/10.1088/1748-3190/ab76d8DOI Listing

On-Line Visual Tracking with Occlusion Handling.

Sensors (Basel) 2020 Feb 10;20(3). Epub 2020 Feb 10.

School of Engineering, RMIT University, Melbourne, VIC 3000, Australia.

One of the core challenges in visual multi-target tracking is occlusion. This is especially important in applications such as video surveillance and sports analytics. While offline batch processing algorithms can utilise future measurements to handle occlusion effectively, online algorithms have to rely on current and past measurements only. Read More

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http://dx.doi.org/10.3390/s20030929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039229PMC
February 2020

Using parametric model order reduction for inverse analysis of large nonlinear cardiac simulations.

Int J Numer Method Biomed Eng 2020 Apr 24;36(4):e3320. Epub 2020 Feb 24.

Institute for Computational Mechanics, Technical University of Munich, Garching b. München, Germany.

Predictive high-fidelity finite element simulations of human cardiac mechanics commonly require a large number of structural degrees of freedom. Additionally, these models are often coupled with lumped-parameter models of hemodynamics. High computational demands, however, slow down model calibration and therefore limit the use of cardiac simulations in clinical practice. Read More

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http://dx.doi.org/10.1002/cnm.3320DOI Listing

H sliding mode control for Markovian jump systems with randomly occurring uncertainties and repeated scalar nonlinearities via delay-fractioning method.

ISA Trans 2020 Jan 27. Epub 2020 Jan 27.

Department of Mathematics, Harbin University of Science and Technology, Harbin 150080, China; Heilongjiang Provincial Key Laboratory of Optimization Control and Intelligent Analysis for Complex Systems, Harbin University of Science and Technology, Harbin 150080, China.

This paper addresses the problem of robust H sliding mode control (SMC) for discrete delayed Markovian jumping systems subject to randomly occurring uncertainties (ROUs) and repeated scalar nonlinearities (RSNs). Here, a set of mutually independent Bernoulli distributed random variables is introduced to model the phenomenon of the ROUs, where the occurrence probabilities could be uncertain. The purpose of paper is to present an H SMC strategy via the delay-fractioning approach such that, for the Markovian jumping parameters, time-varying delays, ROUs and RSNs, the mean-square stability of the resulted sliding motion with a prescribed H performance can be guaranteed. Read More

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http://dx.doi.org/10.1016/j.isatra.2020.01.032DOI Listing
January 2020
2.256 Impact Factor

A theoretical investigation of the nonlinear acoustic response of abrupt area contractions.

J Acoust Soc Am 2020 Jan;147(1):500

Aerospace Engineering Department, Auburn University, Auburn, Alabama 36849, USA.

Acoustic instabilities are frequently the culprit for engine failure. To mitigate these instabilities, an accurate model of the nonlinear acoustic pressure profile of the system is necessary. This study develops a nonlinear model for the acoustic response of an area-contraction. Read More

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http://dx.doi.org/10.1121/10.0000607DOI Listing
January 2020

Simulation of hypoxia PET-tracer uptake in tumours: Dependence of clinical uptake-values on transport parameters and arterial input function.

Phys Med 2020 Feb 29;70:109-117. Epub 2020 Jan 29.

Pontificia Universidad Católica de Chile, Institute of Physics, Santiago, Chile; Instituto de Investigación Sanitaria de Santiago (IDIS), Group of Medical Physics and Biomathematics, Santiago de Compostela, Spain.

Poor radiotherapy outcome is in many cases related to hypoxia, due to the increased radioresistance of hypoxic tumour cells. Positron emission tomography may be used to non-invasively assess the oxygenation status of the tumour using hypoxia-specific radiotracers. Quantification and interpretation of these images remains challenging, since radiotracer binding and oxygen tension are not uniquely related. Read More

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http://dx.doi.org/10.1016/j.ejmp.2020.01.012DOI Listing
February 2020

Three-dimensional multi-source localization of underwater objects using convolutional neural networks for artificial lateral lines.

J R Soc Interface 2020 Jan 22;17(162):20190616. Epub 2020 Jan 22.

Bernoulli Institute of Mathematics, Computer Science and Artificial Intelligence, Faculty of Science and Engineering, University of Groningen, Groningen, The Netherlands.

This research focuses on the signal processing required for a sensory system that can simultaneously localize multiple moving underwater objects in a three-dimensional (3D) volume by simulating the hydrodynamic flow caused by these objects. We propose a method for localization in a simulated setting based on an established hydrodynamic theory founded in fish lateral line organ research. Fish neurally concatenate the information of multiple sensors to localize sources. Read More

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http://dx.doi.org/10.1098/rsif.2019.0616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014811PMC
January 2020

Euler-Bernoulli theory accurately predicts atomic force microscope cantilever shape during non-equilibrium snap-to-contact motion.

Nanotechnology 2020 May 21;31(18):185702. Epub 2020 Jan 21.

Biomedical Engineering Dept., Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44122, United States of America.

We prove that the Euler-Bernoulli elastic beam theory can be reliably used to describe the dynamics of an atomic force microscope cantilever during the far from equilibrium snap-to-contact event. In conventional atomic force microscope operation, force-separation curves are obtained by post-processing voltage versus time traces produced by measuring one point on the cantilever close to the hanging end. In this article, we assess the validity of the Euler-Bernoulli equation during the snap-to-contact event. Read More

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http://dx.doi.org/10.1088/1361-6528/ab6dffDOI Listing

Resting-state EEG reveals global network deficiency in dyslexic children.

Neuropsychologia 2020 02 14;138:107343. Epub 2020 Jan 14.

Institute of Psychological Sciences, Hangzhou Normal University, Hangzhou, China; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, China. Electronic address:

Developmental dyslexia is known to involve dysfunctions in multiple brain regions; however, a clear understanding of the brain networks behind this disorder is still lacking. The present study examined the functional network connectivity in Chinese dyslexic children with resting-state electroencephalography (EEG) recordings. EEG data were recorded from 27 dyslexic children and 40 age-matched controls, and a minimum spanning tree (MST) analysis was performed to examine the network connectivity in the delta, theta, alpha, and beta frequency bands. Read More

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http://dx.doi.org/10.1016/j.neuropsychologia.2020.107343DOI Listing
February 2020

Non-fragile dissipative filtering of cyber-physical systems with random sensor delays.

ISA Trans 2020 Jan 9. Epub 2020 Jan 9.

Zhejiang University of Water Resources and Electric Power, Hangzhou, 310018, PR China. Electronic address:

This paper considers the problem of non-fragile state estimation under dissipative constraint for a class of nonlinear cyber-physical systems (CPSs) with sensor delays. The dynamics of the considered CPSs is characterized by the well-known T-S fuzzy model and system measurements are valued by wireless sensors. The communication link between the filter and the plant is described by a relatively practical model and sensor delays occurred in signal transmissions are taken into consideration. Read More

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http://dx.doi.org/10.1016/j.isatra.2020.01.001DOI Listing
January 2020

Statistical process monitoring to improve quality assurance of inpatient care.

BMC Health Serv Res 2020 Jan 7;20(1):21. Epub 2020 Jan 7.

Institute for Medical Information Processing, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Marchioninistr. 15, Munich, 81377, Germany.

Background: Statistical Process Monitoring (SPM) is not typically used in traditional quality assurance of inpatient care. While SPM allows a rapid detection of performance deficits, SPM results strongly depend on characteristics of the evaluated process. When using SPM to monitor inpatient care, in particular the hospital risk profile, hospital volume and properties of each monitored performance indicator (e. Read More

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http://dx.doi.org/10.1186/s12913-019-4866-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947979PMC
January 2020

A regulated synthetic operon facilitates stable overexpression of multigene terpenoid pathway in Bacillus subtilis.

J Ind Microbiol Biotechnol 2020 Feb 1;47(2):243-249. Epub 2020 Jan 1.

Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.

The creation of microbial cell factories for sustainable production of natural products is important for medical and industrial applications. This requires stable expression of biosynthetic pathways in a host organism with favorable fermentation properties such as Bacillus subtilis. The aim of this study is to construct B. Read More

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http://dx.doi.org/10.1007/s10295-019-02257-4DOI Listing
February 2020

Transition Probabilities of Noise-induced Transitions of the Atlantic Ocean Circulation.

Sci Rep 2019 12 30;9(1):20284. Epub 2019 Dec 30.

Institute for Marine and Atmospheric research Utrecht, Department of Physics, Utrecht University, Utrecht, The Netherlands.

The Atlantic Meridional Overturning Circulation (AMOC) is considered to be a tipping element of the climate system. As it cannot be excluded that the AMOC is in a multiple regime, transitions can occur due to atmospheric noise between the present-day state and a weaker AMOC state. For the first time, we here determine estimates of the transition probability of noise-induced transitions of the AMOC, within a certain time period, using a methodology from large deviation theory. Read More

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http://dx.doi.org/10.1038/s41598-019-56435-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937345PMC
December 2019