826 results match your criteria Beriberi Thiamine Deficiency


Starvation-induced diplopia and weakness: a case of beriberi and Wernicke's encephalopathy.

BMJ Case Rep 2019 Jan 3;12(1). Epub 2019 Jan 3.

Department of Internal Medicine, Singapore General Hospital, Singapore.

A 56-year-old teetotaller man with hypertension and gout presented with a week duration of painless worsening diplopia on a background of loss of weight and appetite, generalised lethargy and weakness for 1 year. On examination, he was noted to be hypothermic and tachycardic with generalised muscle wasting. Proximal myopathy, lower limb fasciculations and areflexia, restricted bilateral eye abduction and nystagmus were observed. Read More

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http://dx.doi.org/10.1136/bcr-2018-227412DOI Listing
January 2019
13 Reads

The Wrong Turn to Tijuana: Dry Beriberi after Gastric Bypass Surgery with Incidental Spinal Stenosis.

Case Rep Neurol 2018 Sep-Dec;10(3):309-313. Epub 2018 Nov 8.

Internal Medicine, Mount Carmel West Hospital, Columbus, Ohio, USA.

Thiamine deficiency is a condition characterized by several different presentations, but one of the most devastating is dry beriberi. It is associated with polyneuropathy and muscle weakness which typically affects the lower extremities and progressively involves the upper extremities. This case outlines a case of a 41-year-old man that presented to the hospital with diffuse weakness and decreased sensation in his legs and hands over a 3-day period. Read More

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https://www.karger.com/Article/FullText/493422
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http://dx.doi.org/10.1159/000493422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276741PMC
November 2018
24 Reads

Beriberi disease in an 11-year-old girl with total colectomy.

Oxf Med Case Reports 2018 Nov 31;2018(11):omy091. Epub 2018 Oct 31.

Department of Pediatric Gastroenterology, Dayton Children's Hospital, Dayton, OH, USA.

Beriberi or vitamin B1 deficiency is a rare disease in the developed world and more common in developing countries due to poverty and malnutrition. It usually presents with neurological manifestations (dry beriberi) or cardiovascular signs (wet beriberi). We report a case of dry beriberi in an 11-year-old girl with total colectomy who presented to our hospital with ataxic gait and muscle weakness. Read More

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https://academic.oup.com/omcr/article/doi/10.1093/omcr/omy09
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http://dx.doi.org/10.1093/omcr/omy091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208053PMC
November 2018
16 Reads

Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs.

Ann N Y Acad Sci 2018 Oct 27;1430(1):3-43. Epub 2018 Aug 27.

Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts.

Thiamine is an essential micronutrient that plays a key role in energy metabolism. Many populations worldwide may be at risk of clinical or subclinical thiamine deficiencies, due to famine, reliance on staple crops with low thiamine content, or food preparation practices, such as milling grains and washing milled rice. Clinical manifestations of thiamine deficiency are variable; this, along with the lack of a readily accessible and widely agreed upon biomarker of thiamine status, complicates efforts to diagnose thiamine deficiency and assess its global prevalence. Read More

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http://dx.doi.org/10.1111/nyas.13919DOI Listing
October 2018
5 Reads

Thiamine Deficiency: An Important Consideration in Critically Ill Patients.

Am J Med Sci 2018 Oct 21;356(4):382-390. Epub 2018 Jun 21.

Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas. Electronic address:

Thiamine is an essential cofactor for 4 enzymes involved in the production of energy (ATP) and the synthesis of essential cellular molecules. The total body stores of thiamine are relatively small, and thiamine deficiency can develop in patients secondary to inadequate nutrition, alcohol use disorders, increased urinary excretion and acute metabolic stress. Patients with sepsis are frequently thiamine deficient, and patients undergoing surgical procedures can develop thiamine deficiency. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029629183022
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http://dx.doi.org/10.1016/j.amjms.2018.06.015DOI Listing
October 2018
22 Reads

Gastrointestinal beriberi: a forme fruste of Wernicke's encephalopathy?

Authors:
Sanjay Prakash

BMJ Case Rep 2018 Jul 6;2018. Epub 2018 Jul 6.

Neurology, Smt B K Shah Medical Institute and Research Centre, Vadodara, Gujarat, India.

Gastrointestinal symptoms, such as anorexia, nausea, vomiting and abdominal pain, are very common in patients with Wernicke's encephalopathy (WE). Mild thiamine deficiency may have only gastrointestinal symptoms. We are reporting two patients with thiamine deficiency who predominantly had gastrointestinal symptoms. Read More

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http://dx.doi.org/10.1136/bcr-2018-224841DOI Listing
July 2018
4 Reads

Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy.

Surg Obes Relat Dis 2018 07 1;14(7):950-951. Epub 2018 May 1.

Duke University Health System, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.soard.2018.04.014DOI Listing
July 2018
3 Reads

Re-emergence of thiamine deficiency disease in the Pacific islands (2014-15): A case-control study.

PLoS One 2018 7;13(6):e0198590. Epub 2018 Jun 7.

Ministry of Health and Medical Services, Nawerewere, Tarawa, Kiribati.

Background: From late 2014 multiple atolls in Kiribati reported an unusual and sometimes fatal illness. We conducted an investigation to identify the etiology of the outbreak on the most severely affected atoll, Kuria, and identified thiamine deficiency disease as the cause. Thiamine deficiency disease has not been reported in the Pacific islands for >5 decades. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198590PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991702PMC
January 2019
6 Reads

Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: A case report and literature review.

Medicine (Baltimore) 2018 Mar;97(9):e0010

Department of Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Rationale: Circulatory failure, especially with low systemic vascular resistance (SVR), as observed in septic shock, thyrotoxicosis, and anemia, is a particular pattern that should suggest thiamine (vitamin B1) deficiency. The clinical picture of wet beriberi secondary to thiamine deficiency only demonstrates non-specific clinical manifestations. For a diagnosis of wet beriberi, medical history is very important. Read More

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http://dx.doi.org/10.1097/MD.0000000000010010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851725PMC
March 2018
15 Reads

Thiamin.

Authors:
Derrick Lonsdale

Adv Food Nutr Res 2018;83:1-56. Epub 2018 Feb 2.

Cleveland Clinic, Cleveland, OH, United States. Electronic address:

Starting with a brief history of beriberi and the discovery that thiamin deficiency is its cause, the symptoms and signs are reviewed. None are pathognomonic. The disease has a low mortality and a long morbidity. Read More

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http://dx.doi.org/10.1016/bs.afnr.2017.11.001DOI Listing
May 2018
4 Reads

Thiamine and Cardiovascular Disease: A Literature Review.

Prog Cardiovasc Dis 2018 May - Jun;61(1):27-32. Epub 2018 Jan 31.

Saint Luke's Mid America Heart Institute, Kansas City, MO, United States.

Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in the human body. Deficiency in thiamine can lead to neurological abnormalities and congestive heart failure (HF), known as dry beriberi and wet beriberi respectively. Several populations are at higher risk for thiamine deficiency, most notably persons with chronic alcoholism. Read More

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http://dx.doi.org/10.1016/j.pcad.2018.01.009DOI Listing
October 2018
7 Reads

Wet Beriberi Associated with Hikikomori Syndrome.

J Gen Intern Med 2018 Mar 29;33(3):384-387. Epub 2017 Nov 29.

Department of Critical Care Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu-city, Japan.

Wet beriberi, characterized by high cardiac output with predominantly right-sided heart failure and lactic acidosis, is a disease caused by thiamine deficiency, and is rarely seen in modern society. However, patients with social withdrawal syndrome, also known as hikikomori syndrome, may be a new population at risk of thiamine deficiency. Hikikomori syndrome, first recognized in Japan, is becoming a worldwide issue. Read More

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http://dx.doi.org/10.1007/s11606-017-4208-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834955PMC
March 2018
12 Reads

Beriberi Outbreak Among Unauthorised Immigrants in a Detention Camp in Malaysia.

J Immigr Minor Health 2018 Oct;20(5):1294-1297

Community and Family Medicine Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, 88300, Kota Kinabalu, Sabah, Malaysia.

In February 2012, a district health authority received three inmates with bilateral leg swelling and difficulty in breathing from a detention camp for unauthorized immigrants. A case control study was conducted. Fasting blood samples of case and control groups were collected according to instructions of the laboratory for determining thiamine level, and their 1 week dietary intake was analyzed. Read More

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http://dx.doi.org/10.1007/s10903-017-0674-5DOI Listing
October 2018
4 Reads

Usefulness of central venous saturation as a predictor of thiamine deficiency in critically ill patients: a case report.

J Intensive Care 2017 6;5:61. Epub 2017 Nov 6.

Department of Cardiovascular Medicine, Graduate school of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 1130033 Japan.

Background: Central venous oxygen saturation (ScvO) reflects the balance of oxygen delivery and consumption. Low ScvO indicates the presence of inadequate oxygen delivery, while high ScvO indicates reduced oxygen consumption and is sometimes associated with a high mortality rate in critically ill patients from dysoxia. Thiamine is an essential cofactor in cellular aerobic metabolism. Read More

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http://dx.doi.org/10.1186/s40560-017-0255-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674760PMC
November 2017
22 Reads

Wernicke-Korsakoff syndrome complicated by subacute beriberi neuropathy in an alcoholic patient.

Clin Neurol Neurosurg 2018 01 8;164:1-4. Epub 2017 Nov 8.

Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, Italy. Electronic address:

Thiamine (vitamin B1) deficiency is a common condition in alcohol abusers, which can lead to damage of both the peripheral and the central nervous systems. Here we describe the case of an alcoholic patient who presented with acute onset of ataxia, severe weakness of the four limbs, and hypoesthesia and dysesthesia of the distal portion of the upper and lower extremities. The clinical picture also included mental confusion and amnesia. Read More

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http://dx.doi.org/10.1016/j.clineuro.2017.11.006DOI Listing
January 2018
17 Reads

A diagnosis and treatment gap for thiamine deficiency disorders in sub-Saharan Africa?

Ann N Y Acad Sci 2017 11 24;1408(1):15-19. Epub 2017 Oct 24.

Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee.

Staple diets that are deficient in thiamine can result in low body thiamine levels, which may be subclinical or may manifest as a thiamine-deficiency syndrome. In many communities in the developing countries of Africa, the staple diets of polished rice or processed cassava are deficient in thiamine, and thus the communities are at high risk for marginal or frank thiamine deficiency unless their diets are supplemented by other sources of thiamine, such as protein meals and vegetables. African communities with large numbers of individuals in low socioeconomic strata are more likely to subsist on a monotonous diet of rice or cassava with minimal or no protein supplementation and are therefore particularly at risk of thiamine-deficiency disorders. Read More

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http://dx.doi.org/10.1111/nyas.13509DOI Listing
November 2017
2 Reads

Thiamine content of F-75 therapeutic milk for complicated severe acute malnutrition: time for a change?

Ann N Y Acad Sci 2017 09 14;1404(1):20-26. Epub 2017 Sep 14.

Pediatric Neurology Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Since community-based management of severe acute malnutrition has become the standard of care, the clinical profile of severe acutely malnourished patients admitted to hospitals or inpatient therapeutic feeding centers has changed significantly. These patients are usually very ill and often present with several comorbidities, such as shock, sepsis, and pneumonia. Complicated severe acute malnutrition patients are at risk of thiamine insufficiency, and critically ill patients have higher thiamine requirements. Read More

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http://dx.doi.org/10.1111/nyas.13458DOI Listing
September 2017
5 Reads

High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children.

PLoS Negl Trop Dis 2017 Sep 5;11(9):e0005814. Epub 2017 Sep 5.

Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France.

Background: Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15-49 y) and their young children (6-69 mo). Read More

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http://dx.doi.org/10.1371/journal.pntd.0005814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600402PMC
September 2017
14 Reads

Nonalcoholic Wernicke's Encephalopathy: A Retrospective Study from a Tertiary Care Center in Northern India.

J Neurosci Rural Pract 2017 Jul-Sep;8(3):401-406

Department of Food Sciences and Technology, University of Kashmir, Srinagar, Jammu and Kashmir, India.

Objective: The objective of this study was to describe the demographic features, clinical presentation, and management and outcome of fifty cases of nonalcoholic Wernicke's encephalopathy from a tertiary care hospital of a region with reported incidence of thiamine deficiency disorders.

Materials And Methods: In a retrospective study, fifty adult cases of Wernicke's encephalopathy were analyzed. The diagnosis of Wernicke's encephalopathy was made according to the European federation of neurological societies guidelines 2010. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_14_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488561PMC
July 2017
11 Reads

Wernicke's encephalopathy in exclusive breastfed infants.

World J Pediatr 2017 Oct 24;13(5):485-488. Epub 2017 May 24.

Department of Pediatrics, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.

Background: Kashmir has a population that largely consumes polished rice which is deficient in thiamine. Furthermore, lactating women in this region are prone to severe thiamine deficiency because of their traditional food avoidance practices. Infantile beriberi is common in exclusively breastfed infants of thiamine deficient mothers in Kashmir. Read More

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http://dx.doi.org/10.1007/s12519-017-0039-0DOI Listing
October 2017
30 Reads

A Large Outbreak of Thiamine Deficiency Among Illegal Gold Miners in French Guiana.

Am J Trop Med Hyg 2017 05;96(5):1248-1252

Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane, Cayenne, French Guiana, France.

From September 2013 to July 2014, several gold miners working in the tropical forest consulted the Maripasoula Health Center in French Guiana for edema and findings consistent with right-sided cardiac failure. Of the 42 cases of beriberi that were diagnosed, one patient died. The laboratory and clinical investigation demonstrated vitamin B1 deficiency in most of the patients tested. Read More

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http://dx.doi.org/10.4269/ajtmh.15-0906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417225PMC
May 2017
38 Reads

No Camphor Toxicity in Cambodian Infants.

Glob Pediatr Health 2017 24;4:2333794X17702980. Epub 2017 Apr 24.

Mayo Clinic, Rochester, MN, USA.

Thiamine deficiency and beriberi are prevalent in Cambodia, although most infants with nonspecific clinical symptoms of beriberi, including tachypnea, lack echocardiographic evidence diagnostic of the disease. Camphor activates transient receptor potential vanilloid 3 (TRPV3), a nonselective ion channel expressed in the medial preoptic nucleus of the hypothalamus and thought to be important for thermo-sensitivity. Because camphorated ointments are used commonly among Cambodian infants, we hypothesized that topical camphor modulates thermoregulatory behaviors, causing beriberi-simulating tachypnea, separate from any influence of thiamine deficiency. Read More

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http://dx.doi.org/10.1177/2333794X17702980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406147PMC
April 2017
9 Reads

Thiamine Assays-Advances, Challenges, and Caveats.

ChemistryOpen 2017 04 8;6(2):178-191. Epub 2017 Mar 8.

Department of Natural Resources Cornell University Ithaca NY 14853 USA.

Thiamine (vitamin B1) is essential to the health of all living organisms and deficiency has long been associated with diseases in animals such as fish, birds, alligators, and domesticated ruminant mammals. Thiamine is also implicated in several human diseases including Alzheimer's, diabetes, dementia, depression and, most notably, Wernicke-Korsakoff syndrome and Beriberi disease. Yet, highly sensitive and specific detection of thiamine remains an analytical challenge, as pM to nm levels of thiamine need to be detected in environmental and human samples, respectively, various phosphorylated variants need to be discriminated, and rapid on-site detection would be highly desirable. Read More

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http://dx.doi.org/10.1002/open.201600160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390807PMC
April 2017
14 Reads

[Wernicke encephalopathy and dry beriberi; late complications after bariatric surgery performed on a patient with a psychiatric history].

Tijdschr Psychiatr 2017 ;59(2):116-120

A 38-year-old woman was admitted in a psychiatric hospital because of memory disorders. Dry beriberi and Korsakoff's syndrome, as a late neuropsychiatric manifestation of Wernicke's encephalopathy, were established. The beriberi symptoms decreased slowly, but the patient's memory impairments persisted. Read More

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February 2018
6 Reads

Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India.

Indian Heart J 2017 Jan - Feb;69(1):24-27. Epub 2016 Aug 2.

Department of Pediatrics, SKIMS Srinagar, J&K, India. Electronic address:

Objective: To study the effect of thiamine administration on the resolution of pulmonary hypertension in exclusively breastfed infants.

Design: Prospective cohort study.

Setting: Hospital based study of a tertiary care hospital. Read More

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http://dx.doi.org/10.1016/j.ihj.2016.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319119PMC
October 2017
22 Reads

Prevalence of clinical thiamine deficiency in individuals with medically complicated obesity.

Nutr Res 2017 Jan 1;37:29-36. Epub 2016 Dec 1.

Center for Advanced Laparoscopic General & Bariatric Surgery, MedStar-Washington Hospital Center and Georgetown University School of Medicine, Washington, DC 20010, USA. Electronic address:

Thiamine is a vitamin whose deficient can result in multiorgan symptoms. We described an 18% prevalence of clinical thiamine deficiency after gastric bypass surgery. Our hypotheses are that individuals with medically complicated obesity frequently have clinical thiamine deficiency and that diabetes mellitus is a mechanism for development of clinical thiamine deficiency. Read More

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http://dx.doi.org/10.1016/j.nutres.2016.11.012DOI Listing
January 2017
9 Reads

Thiamine Deprivation Produces a Liver ATP Deficit and Metabolic and Genomic Effects in Mice: Findings Are Parallel to Those of Biotin Deficiency and Have Implications for Energy Disorders.

J Nutrigenet Nutrigenomics 2016 18;9(5-6):287-299. Epub 2017 Feb 18.

Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas UNAM - Instituto Nacional de Pediatría, Mexico City, Mexico.

Thiamine is one of several essential cofactors for ATP generation. Its deficiency, like in beriberi and in the Wernicke-Korsakoff syndrome, has been studied for many decades. However, its mechanism of action is still not completely understood at the cellular and molecular levels. Read More

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http://dx.doi.org/10.1159/000456663DOI Listing
November 2017
19 Reads

Commentary: Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge.

Front Nutr 2016 16;3:58. Epub 2017 Jan 16.

Pediatrics, Discipline of Nutrition and Metabolism, Federal University of São Paulo , São Paulo , Brazil.

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http://journal.frontiersin.org/article/10.3389/fnut.2016.000
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http://dx.doi.org/10.3389/fnut.2016.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237637PMC
January 2017
5 Reads

Beriberi Induced Cardiomyopathy Requiring Salvage Venoarterial Extracorporeal Membrane Oxygenation.

Case Rep Crit Care 2016 5;2016:5043818. Epub 2016 Dec 5.

Advocate Christ Medical Center, Oak Lawn, IL, USA.

Beriberi refers to a constellation of symptoms caused primarily by thiamine (vitamin B1) deficiency. An acute and fulminant presentation of this rare condition has been described in the literature as "Shoshin" beriberi which is characterized by catastrophic cardiovascular collapse. Early recognition and treatment lead to dramatic improvements of symptoms. Read More

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http://dx.doi.org/10.1155/2016/5043818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165147PMC
December 2016
3 Reads

When Was B1, the First Vitamin, Discovered?: An Alternative Perspective.

Authors:
Shozo Sugiura

J Nutr Sci Vitaminol (Tokyo) 2016 ;62(5):372-374

School of Environmental Sciences University of Shiga Prefecture.

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http://dx.doi.org/10.3177/jnsv.62.372DOI Listing
June 2017
6 Reads

[Beriberi 10 years after gastric bypass surgery - case report].

Laeknabladid 2016 Nov;102(11):497-499

Beriberi is primarily related to malnutrition, but also known as a complication following abdominal surgical procedures. A 41 year old woman, who underwent gastric bypass surgery 10 years earlier, presented at the emergency department of Landspitali with general weakness and paresthesia. Physical examination revealed muscle atrophy and attenuated deep tendon reflexes in her lower limbs; presenting as polyneuropathy due to beriberi. Read More

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http://dx.doi.org/10.17992/lbl.2016.11.107DOI Listing
November 2016
6 Reads

Perinatal Consumption of Thiamine-Fortified Fish Sauce in Rural Cambodia: A Randomized Clinical Trial.

JAMA Pediatr 2016 Oct 3;170(10):e162065. Epub 2016 Oct 3.

Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia, Canada9South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia10Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia.

Importance: Infantile beriberi, a potentially fatal disease caused by thiamine deficiency, remains a public health concern in Cambodia and regions where thiamine-poor white rice is a staple food. Low maternal thiamine intake reduces breast milk thiamine concentrations, placing breastfed infants at risk of beriberi.

Objective: To determine if consumption of thiamine-fortified fish sauce yields higher erythrocyte thiamine diphosphate concentrations (eTDP) among lactating women and newborn infants and higher breast milk thiamine concentrations compared with a control sauce. Read More

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http://dx.doi.org/10.1001/jamapediatrics.2016.2065DOI Listing
October 2016
14 Reads

An unusual case of cardiogenic shock in which thiamine administration led to reversal of lactic acidosis and heart function recovery: Shoshin beriberi in an adolescent.

Int J Cardiol 2016 Nov 30;222:401-403. Epub 2016 Jul 30.

Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2016.07.248DOI Listing
November 2016
14 Reads

Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge.

Front Nutr 2016 14;3:16. Epub 2016 Jun 14.

Pediatric Team, Medical Department, Médecins Sans Frontières (MSF) , Barcelona , Spain.

In humans, thiamine is a micronutrient prone to depletion that may result in severe clinical abnormalities. This narrative review summarizes current knowledge on thiamine deficiency (TD) and bridges the gap between pathophysiology and clinical presentation by integrating thiamine metabolism at subcellular level with its function to vital organs. The broad clinical spectrum of TD is outlined, with emphasis on conditions encountered in tropical pediatric practice. Read More

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http://dx.doi.org/10.3389/fnut.2016.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906235PMC
July 2016
10 Reads

Acute Abdominal Pain as a Presenting Symptom of Beriberi in a Pediatric Patient.

J Trop Pediatr 2016 12 20;62(6):490-495. Epub 2016 Jun 20.

Departamento de Pediatria, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP - São Paulo, CP 6109, Brazil

Vitamin B1 (thiamine) plays a fundamental role in the proper functioning of the nervous and cardiovascular systems and in glucose metabolism. Because of the inability of the human body to store large amounts of vitamin, continuous restoration through diet is necessary. In the pediatric population, thiamine deficiency has a broad spectrum of clinical presentations, making diagnosis difficult. Read More

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http://dx.doi.org/10.1093/tropej/fmw039DOI Listing
December 2016
6 Reads

The influence of infantile thiamine deficiency on primary dentition.

Clin Oral Investig 2017 May 17;21(4):1309-1313. Epub 2016 Jun 17.

Pediatric Dental Unit, Barzilai Medical Center, Ashkelon, Israel.

Objectives: The present study explored the histological and chemical effects of infantile thiamine deficiency (ITD) on enamel development through the examination of exfoliated deciduous teeth from a patient who had been fed during his first year of life with a thiamine-deficient milk substitute.

Materials And Methods: Ground sections derived from six exfoliated primary teeth were examined. Slices from a light microscope were photographed for histological analysis. Read More

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http://dx.doi.org/10.1007/s00784-016-1875-3DOI Listing
May 2017
5 Reads

[Clinical appearance and scalable profile Thiamine deficiency in prison in Guinea: study of thirty-eight observations].

Bull Soc Pathol Exot 2016 May 29;109(2):70-6. Epub 2016 Mar 29.

CHU, Conakry, Guinée.

Cardiovascular and neurological manifestations associated with thiamine deficiency in Guinean prisons are common but not reported.We performed a prospective study of 38 cases related to vitamin B1 deficiency over a period of 4 years. In this population, the literature of traditional data gathered: frequency peak after thirty (92. Read More

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http://dx.doi.org/10.1007/s13149-016-0484-3DOI Listing
May 2016
9 Reads

Case report: pericardial effusion with constrictive physiology in a patient with wet beriberi.

Nutr J 2016 Apr 8;15:37. Epub 2016 Apr 8.

Disease Control and Homeostasis, Graduate School of Medical Science, Kanazawa, University, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.

Wet beriberi-induced pericardial effusion has rarely been previously described. Little is known about the effect of beriberi-induced pericardial effusion on hemodynamics. Here we present a case of wet beriberi with pericardial effusion that exhibited constrictive physiology, which was dramatically improved after treatment. Read More

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http://dx.doi.org/10.1186/s12937-016-0156-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826515PMC
April 2016
5 Reads

Cranial Ultrasonography in Infantile Encephalitic Beriberi: A Useful First-Line Imaging Tool for Screening and Diagnosis in Suspected Cases.

AJNR Am J Neuroradiol 2016 08 7;37(8):1535-40. Epub 2016 Apr 7.

Department of Radiology (N.A.C.), SheriKasmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Background And Purpose: Brain imaging is central to the diagnosis of infantile encephalitic beriberi. Because cranial sonography findings have not been described in infantile encephalitic beriberi, our aim was to investigate its role in the diagnosis of this condition.

Materials And Methods: We performed a retrospective review of head sonography of infants (admitted between November 1, 2014, and March 31, 2015) who presented with encephalopathy. Read More

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http://dx.doi.org/10.3174/ajnr.A4756DOI Listing
August 2016
26 Reads

Thiamine deficiency in tachypnoeic Cambodian infants.

Paediatr Int Child Health 2015 ;35(4):312-8

Mayo Medical School.

Background: Beriberi is endemic in South-east Asia. Diagnosis is based on clinical findings, but correlation of clinical features with blood thiamine concentrations is uncertain.

Objectives: To investigate in tachypnoeic Cambodian infants the correlation between whole blood thiamine diphosphate (TDP) concentrations, clinical findings and blood TDP levels after therapy. Read More

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http://angkorhospital.org/wp-content/uploads/2014/10/B1%20de
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http://www.tandfonline.com/doi/full/10.1080/20469047.2015.11
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http://dx.doi.org/10.1080/20469047.2015.1109226DOI Listing
October 2016
14 Reads
4 Citations
0.871 Impact Factor

Beriberi in Cambodia.

Authors:
François Nosten

Paediatr Int Child Health 2015 ;35(4):283-4

Shoklo Malaria Research Unit , Mae Sot, Thailand.

Beriberi had plagued humans for centuries. It was responsible for over 50% of infant deaths in the Philippines in the early 1900s. But since the discovery of its cause and treatment it has become a rarity, or has it? Read More

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http://dx.doi.org/10.1080/20469047.2015.1109246DOI Listing
August 2016
5 Reads

Wernicke's Encephalopathy, Wet Beriberi, and Polyneuropathy in a Patient with Folate and Thiamine Deficiency Related to Gastric Phytobezoar.

Case Rep Neurol Med 2015 30;2015:624807. Epub 2015 Nov 30.

Severo Ochoa Hospital, Leganés, 28911 Madrid, Spain.

Background. Wernicke's encephalopathy (WE) is an acute neurological disorder resulting from thiamine deficiency. It is mainly related to alcohol abuse but it can be associated with other conditions such as gastrointestinal disorders. Read More

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http://dx.doi.org/10.1155/2015/624807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677180PMC
December 2015
13 Reads

Severe Lactic Acidosis in a Parenteral Nutrition-Dependent Teenager with Ulcerative Colitis.

Dig Dis Sci 2016 10 20;61(10):2804-2806. Epub 2015 Nov 20.

Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, USA.

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http://dx.doi.org/10.1007/s10620-015-3961-9DOI Listing
October 2016
3 Reads

High-Output Heart Failure Caused by Thyrotoxicosis and Beriberi.

Authors:
Brenda McCulloch

Crit Care Nurs Clin North Am 2015 Dec 2;27(4):499-510. Epub 2015 Sep 2.

Sutter Medical Center, 2801 L Street, Sacramento, CA 95816, USA. Electronic address:

High-output heart failure is not seen as commonly as low-output heart failure and some of the typical guideline recommendations may not benefit patients with high-output failure. High-output failure is caused by several diseases, including thyrotoxicosis and beriberi, highlighted in this article. Thyrotoxicosis, caused by excessive thyroid hormone production, has profound hemodynamic effects. Read More

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http://dx.doi.org/10.1016/j.cnc.2015.07.004DOI Listing
December 2015
3 Reads

Dry beriberi preceded Wernicke's encephalopathy: Thiamine deficiency after laparoscopic sleeve gastrectomy.

Authors:
Debopam Samanta

J Pediatr Neurosci 2015 Jul-Sep;10(3):297-9

Division of Child Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

In recent times, pediatric obesity has become widely prevalent. If first-line treatment with lifestyle modification fails, bariatric surgery may be indicated for severely obese patients. Many patients now travel abroad to get these surgeries done. Read More

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http://dx.doi.org/10.4103/1817-1745.165732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611911PMC
November 2015
5 Reads

Thiamine responsive acute life threatening metabolic acidosis in exclusively breast-fed infants.

Nutrition 2016 Feb 2;32(2):213-6. Epub 2015 Sep 2.

GMC Srinagar, GB Pant Hospital, Department of Pediatrics, Kashmir, India.

Background: Acute life threatening metabolic acidosis in exclusively breast fed infants due to thiamine deficiency is not described. Kashmir valley, a north Indian state has a population that largely consumes polished rice.

Methods: A six months prospective descriptive study of infants who presented with acute life threatening metabolic acidosis (Blood pH ≤ 7. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08999007150034
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http://dx.doi.org/10.1016/j.nut.2015.08.007DOI Listing
February 2016
23 Reads

Beriberi: an uncommon complication of sleeve gastrectomy.

Surg Obes Relat Dis 2015 Nov-Dec;11(6):e53-5. Epub 2015 Jul 17.

Surgery Department, Hospital Clinico Universitario Virgen de la Arrixaca, Murcia, Spain.

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http://dx.doi.org/10.1016/j.soard.2015.07.008DOI Listing
October 2016
6 Reads

[An Uncommon Diagnosis].

Praxis (Bern 1994) 2015 Oct;104(21):1151-6

1 Universitätsklinik für Endokrinologie, Diabetologie und Klinische Ernährung, Inselspital Bern.

We report on a 61-year-old patient who suffered from severe protein-energy malnutrition due to an inadequately treated exocrine pancreatic insufficiency. In this context, a thiamine deficiency was not recognized and there were clinical manifestations of beriberi disease with decompensated biventricular heart failure. In the course of time, a manifest niacin deficiency (pellagra) with dermatitis, diarrhea and persistent delirium occurred, which was recognized and could be treated. Read More

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http://dx.doi.org/10.1024/1661-8157/a002163DOI Listing
October 2015
9 Reads

Sudden infant death syndrome and abnormal metabolism of thiamin.

Authors:
Derrick Lonsdale

Med Hypotheses 2015 Dec 14;85(6):922-6. Epub 2015 Sep 14.

Associate Emeritus, Cleveland Clinic Foundation, Cleveland, OH, United States. Electronic address:

Although it has been generally accepted that moving the infant from the prone to the supine position has solved the problem of sudden infant death syndrome (SIDS), it has been hypothesized that this is an insufficient explanation and that a mixture of genetic risk, some form of stressful incident and marginal brain metabolism is proportionately required. It is suggested that each of these three variables, with dominance in one or more of them, act together in the common etiology. Much has been written about the association of thiamin and magnesium but the finding of extremely high concentrations of serum thiamin in SIDs victims has largely caused rejection of thiamin as being involved in the etiology. Read More

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http://dx.doi.org/10.1016/j.mehy.2015.09.009DOI Listing
December 2015
9 Reads