938 results match your criteria Beriberi


The Wrong Turn to Tijuana: Dry Beriberi after Gastric Bypass Surgery with Incidental Spinal Stenosis.

Case Rep Neurol 2018 Sep-Dec;10(3):309-313. Epub 2018 Nov 8.

Internal Medicine, Mount Carmel West Hospital, Columbus, Ohio, USA.

Thiamine deficiency is a condition characterized by several different presentations, but one of the most devastating is dry beriberi. It is associated with polyneuropathy and muscle weakness which typically affects the lower extremities and progressively involves the upper extremities. This case outlines a case of a 41-year-old man that presented to the hospital with diffuse weakness and decreased sensation in his legs and hands over a 3-day period. Read More

View Article
November 2018
4 Reads

Beriberi disease in an 11-year-old girl with total colectomy.

Oxf Med Case Reports 2018 Nov 31;2018(11):omy091. Epub 2018 Oct 31.

Department of Pediatric Gastroenterology, Dayton Children's Hospital, Dayton, OH, USA.

Beriberi or vitamin B1 deficiency is a rare disease in the developed world and more common in developing countries due to poverty and malnutrition. It usually presents with neurological manifestations (dry beriberi) or cardiovascular signs (wet beriberi). We report a case of dry beriberi in an 11-year-old girl with total colectomy who presented to our hospital with ataxic gait and muscle weakness. Read More

View Article
November 2018
11 Reads

Occupational, physical, sexual and mental health and violence among migrant and trafficked commercial fishers and seafarers from the Greater Mekong Subregion (GMS): systematic review.

Glob Health Res Policy 2018 1;3:28. Epub 2018 Oct 1.

5Section of Women's Mental Health, Institute of Psychiatry, Psychology and Neuroscience, 16 De Crespigny Park, Kings College London, London, SE5 8AF UK.

Background: Little is known about the health of GMS commercial fishers and seafarers, many of whom are migrants and some trafficked. This systematic review summarizes evidence on occupational, physical, sexual and mental health and violence among GMS commercial fishers/seafarers.

Methods: We searched 5 electronic databases and purposively searched grey literature. Read More

View Article
October 2018
1 Read

Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs.

Ann N Y Acad Sci 2018 Oct 27;1430(1):3-43. Epub 2018 Aug 27.

Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts.

Thiamine is an essential micronutrient that plays a key role in energy metabolism. Many populations worldwide may be at risk of clinical or subclinical thiamine deficiencies, due to famine, reliance on staple crops with low thiamine content, or food preparation practices, such as milling grains and washing milled rice. Clinical manifestations of thiamine deficiency are variable; this, along with the lack of a readily accessible and widely agreed upon biomarker of thiamine status, complicates efforts to diagnose thiamine deficiency and assess its global prevalence. Read More

View Article
October 2018
3 Reads

Thiamine Deficiency: An Important Consideration in Critically Ill Patients.

Am J Med Sci 2018 Oct 21;356(4):382-390. Epub 2018 Jun 21.

Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas. Electronic address:

Thiamine is an essential cofactor for 4 enzymes involved in the production of energy (ATP) and the synthesis of essential cellular molecules. The total body stores of thiamine are relatively small, and thiamine deficiency can develop in patients secondary to inadequate nutrition, alcohol use disorders, increased urinary excretion and acute metabolic stress. Patients with sepsis are frequently thiamine deficient, and patients undergoing surgical procedures can develop thiamine deficiency. Read More

View Article
October 2018
13 Reads

Hairs in old books isotopically reconstruct the eating habits of early modern Japan.

Sci Rep 2018 Aug 14;8(1):12152. Epub 2018 Aug 14.

National Institute of Japanese Literature, Midori-cho, Tachikawa, Tokyo, 190-0014, Japan.

To complement literature-based historical knowledge of the eating habits of 17th- and 18th-century Japan, we analysed carbon and nitrogen isotope ratios (δC and δN, respectively) of human hairs embedded in cover paper of Japanese books printed during 1690s-1890s, taking regional and temporal variations into consideration. We purchased 24 book sets from second-hand book markets. Twenty-three sets contained enough human hairs, which were non-destructively extracted from the thick, recycled paper of the book covers and used to measure the δC and δN values, found to be identical within each book set. Read More

View Article
August 2018
9 Reads

Gastrointestinal beriberi: a forme fruste of Wernicke's encephalopathy?

Authors:
Sanjay Prakash

BMJ Case Rep 2018 Jul 6;2018. Epub 2018 Jul 6.

Neurology, Smt B K Shah Medical Institute and Research Centre, Vadodara, Gujarat, India.

Gastrointestinal symptoms, such as anorexia, nausea, vomiting and abdominal pain, are very common in patients with Wernicke's encephalopathy (WE). Mild thiamine deficiency may have only gastrointestinal symptoms. We are reporting two patients with thiamine deficiency who predominantly had gastrointestinal symptoms. Read More

View Article
July 2018
2 Reads

Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy.

Surg Obes Relat Dis 2018 07 1;14(7):950-951. Epub 2018 May 1.

Duke University Health System, Durham, North Carolina.

View Article
July 2018
2 Reads

Re-emergence of thiamine deficiency disease in the Pacific islands (2014-15): A case-control study.

PLoS One 2018 7;13(6):e0198590. Epub 2018 Jun 7.

Ministry of Health and Medical Services, Nawerewere, Tarawa, Kiribati.

Background: From late 2014 multiple atolls in Kiribati reported an unusual and sometimes fatal illness. We conducted an investigation to identify the etiology of the outbreak on the most severely affected atoll, Kuria, and identified thiamine deficiency disease as the cause. Thiamine deficiency disease has not been reported in the Pacific islands for >5 decades. Read More

View Article
June 2018
6 Reads

Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: A case report and literature review.

Medicine (Baltimore) 2018 Mar;97(9):e0010

Department of Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Rationale: Circulatory failure, especially with low systemic vascular resistance (SVR), as observed in septic shock, thyrotoxicosis, and anemia, is a particular pattern that should suggest thiamine (vitamin B1) deficiency. The clinical picture of wet beriberi secondary to thiamine deficiency only demonstrates non-specific clinical manifestations. For a diagnosis of wet beriberi, medical history is very important. Read More

View Article
March 2018
13 Reads

Thiamin.

Authors:
Derrick Lonsdale

Adv Food Nutr Res 2018;83:1-56. Epub 2018 Feb 2.

Cleveland Clinic, Cleveland, OH, United States. Electronic address:

Starting with a brief history of beriberi and the discovery that thiamin deficiency is its cause, the symptoms and signs are reviewed. None are pathognomonic. The disease has a low mortality and a long morbidity. Read More

View Article
May 2018
2 Reads

Thiamine and Cardiovascular Disease: A Literature Review.

Prog Cardiovasc Dis 2018 May - Jun;61(1):27-32. Epub 2018 Jan 31.

Saint Luke's Mid America Heart Institute, Kansas City, MO, United States.

Thiamine is a water-soluble vitamin that plays an important role in the energy metabolism in the human body. Deficiency in thiamine can lead to neurological abnormalities and congestive heart failure (HF), known as dry beriberi and wet beriberi respectively. Several populations are at higher risk for thiamine deficiency, most notably persons with chronic alcoholism. Read More

View Article
October 2018
6 Reads

Wet Beriberi Associated with Hikikomori Syndrome.

J Gen Intern Med 2018 Mar 29;33(3):384-387. Epub 2017 Nov 29.

Department of Critical Care Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu-city, Japan.

Wet beriberi, characterized by high cardiac output with predominantly right-sided heart failure and lactic acidosis, is a disease caused by thiamine deficiency, and is rarely seen in modern society. However, patients with social withdrawal syndrome, also known as hikikomori syndrome, may be a new population at risk of thiamine deficiency. Hikikomori syndrome, first recognized in Japan, is becoming a worldwide issue. Read More

View Article
March 2018
10 Reads

Beriberi Outbreak Among Unauthorised Immigrants in a Detention Camp in Malaysia.

J Immigr Minor Health 2018 Oct;20(5):1294-1297

Community and Family Medicine Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, 88300, Kota Kinabalu, Sabah, Malaysia.

In February 2012, a district health authority received three inmates with bilateral leg swelling and difficulty in breathing from a detention camp for unauthorized immigrants. A case control study was conducted. Fasting blood samples of case and control groups were collected according to instructions of the laboratory for determining thiamine level, and their 1 week dietary intake was analyzed. Read More

View Article
October 2018
4 Reads

Usefulness of central venous saturation as a predictor of thiamine deficiency in critically ill patients: a case report.

J Intensive Care 2017 6;5:61. Epub 2017 Nov 6.

Department of Cardiovascular Medicine, Graduate school of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 1130033 Japan.

Background: Central venous oxygen saturation (ScvO) reflects the balance of oxygen delivery and consumption. Low ScvO indicates the presence of inadequate oxygen delivery, while high ScvO indicates reduced oxygen consumption and is sometimes associated with a high mortality rate in critically ill patients from dysoxia. Thiamine is an essential cofactor in cellular aerobic metabolism. Read More

View Article
November 2017
17 Reads

Wernicke-Korsakoff syndrome complicated by subacute beriberi neuropathy in an alcoholic patient.

Clin Neurol Neurosurg 2018 01 8;164:1-4. Epub 2017 Nov 8.

Department of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, Italy. Electronic address:

Thiamine (vitamin B1) deficiency is a common condition in alcohol abusers, which can lead to damage of both the peripheral and the central nervous systems. Here we describe the case of an alcoholic patient who presented with acute onset of ataxia, severe weakness of the four limbs, and hypoesthesia and dysesthesia of the distal portion of the upper and lower extremities. The clinical picture also included mental confusion and amnesia. Read More

View Article
January 2018
14 Reads

A diagnosis and treatment gap for thiamine deficiency disorders in sub-Saharan Africa?

Ann N Y Acad Sci 2017 11 24;1408(1):15-19. Epub 2017 Oct 24.

Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee.

Staple diets that are deficient in thiamine can result in low body thiamine levels, which may be subclinical or may manifest as a thiamine-deficiency syndrome. In many communities in the developing countries of Africa, the staple diets of polished rice or processed cassava are deficient in thiamine, and thus the communities are at high risk for marginal or frank thiamine deficiency unless their diets are supplemented by other sources of thiamine, such as protein meals and vegetables. African communities with large numbers of individuals in low socioeconomic strata are more likely to subsist on a monotonous diet of rice or cassava with minimal or no protein supplementation and are therefore particularly at risk of thiamine-deficiency disorders. Read More

View Article
November 2017
2 Reads

The Study on the Lives and Health Conditions of Internees in Santo Thomas Camp of Philippines - Based on McAnlis's The War in Manila (1941-1945).

Uisahak 2017 Aug;26(2):265-314

Baeksang Dental Clinic.

When Japan invaded the Philippines, two missionary dentists (Dr. McAnlis and Dr. Boots) who were forced to leave Korea were captured and interned in the Santo Thomas camp in Manila. Read More

View Article
August 2017
4 Reads

Thiamine content of F-75 therapeutic milk for complicated severe acute malnutrition: time for a change?

Ann N Y Acad Sci 2017 09 14;1404(1):20-26. Epub 2017 Sep 14.

Pediatric Neurology Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Since community-based management of severe acute malnutrition has become the standard of care, the clinical profile of severe acutely malnourished patients admitted to hospitals or inpatient therapeutic feeding centers has changed significantly. These patients are usually very ill and often present with several comorbidities, such as shock, sepsis, and pneumonia. Complicated severe acute malnutrition patients are at risk of thiamine insufficiency, and critically ill patients have higher thiamine requirements. Read More

View Article
September 2017
3 Reads

High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children.

PLoS Negl Trop Dis 2017 Sep 5;11(9):e0005814. Epub 2017 Sep 5.

Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France.

Background: Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15-49 y) and their young children (6-69 mo). Read More

View Article
September 2017
10 Reads

Role of Green Tea Flavonoids and Other Related Contents in Cancer Prevention.

Crit Rev Eukaryot Gene Expr 2017 ;27(2):163-171

Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.

Green tea is made from Camellia sinensis and leaves through the oxidation process. It mainly originates in China and has been used traditionally throughout Asia. In the West, black tea has been used mostly, but green tea has become the most popular beverage throughout the world. Read More

View Article
September 2017

Yeast caspase-dependent apoptosis in Saccharomyces cerevisiae BY4742 induced by antifungal and potential antitumor agent clotrimazole.

Arch Microbiol 2018 Jan 17;200(1):97-106. Epub 2017 Aug 17.

Department of Chemistry, Faculty of Science, University of Dokuz Eylul, Tinaztepe Campus, 35160, Buca, Izmir, Turkey.

Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections. There is also promising research on using clotrimazole against other diseases such as malaria, beriberi, tineapedis and cancer. It was aimed to investigate the apoptotic phenotype in Saccharomyces cerevisiae induced by clotrimazole. Read More

View Article
January 2018
6 Reads

Nonalcoholic Wernicke's Encephalopathy: A Retrospective Study from a Tertiary Care Center in Northern India.

J Neurosci Rural Pract 2017 Jul-Sep;8(3):401-406

Department of Food Sciences and Technology, University of Kashmir, Srinagar, Jammu and Kashmir, India.

Objective: The objective of this study was to describe the demographic features, clinical presentation, and management and outcome of fifty cases of nonalcoholic Wernicke's encephalopathy from a tertiary care hospital of a region with reported incidence of thiamine deficiency disorders.

Materials And Methods: In a retrospective study, fifty adult cases of Wernicke's encephalopathy were analyzed. The diagnosis of Wernicke's encephalopathy was made according to the European federation of neurological societies guidelines 2010. Read More

View Article
July 2017
8 Reads

Wernicke's encephalopathy in exclusive breastfed infants.

World J Pediatr 2017 Oct 24;13(5):485-488. Epub 2017 May 24.

Department of Pediatrics, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.

Background: Kashmir has a population that largely consumes polished rice which is deficient in thiamine. Furthermore, lactating women in this region are prone to severe thiamine deficiency because of their traditional food avoidance practices. Infantile beriberi is common in exclusively breastfed infants of thiamine deficient mothers in Kashmir. Read More

View Article
October 2017
26 Reads

A Large Outbreak of Thiamine Deficiency Among Illegal Gold Miners in French Guiana.

Am J Trop Med Hyg 2017 05;96(5):1248-1252

Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane, Cayenne, French Guiana, France.

From September 2013 to July 2014, several gold miners working in the tropical forest consulted the Maripasoula Health Center in French Guiana for edema and findings consistent with right-sided cardiac failure. Of the 42 cases of beriberi that were diagnosed, one patient died. The laboratory and clinical investigation demonstrated vitamin B1 deficiency in most of the patients tested. Read More

View Article
May 2017
29 Reads

No Camphor Toxicity in Cambodian Infants.

Glob Pediatr Health 2017 24;4:2333794X17702980. Epub 2017 Apr 24.

Mayo Clinic, Rochester, MN, USA.

Thiamine deficiency and beriberi are prevalent in Cambodia, although most infants with nonspecific clinical symptoms of beriberi, including tachypnea, lack echocardiographic evidence diagnostic of the disease. Camphor activates transient receptor potential vanilloid 3 (TRPV3), a nonselective ion channel expressed in the medial preoptic nucleus of the hypothalamus and thought to be important for thermo-sensitivity. Because camphorated ointments are used commonly among Cambodian infants, we hypothesized that topical camphor modulates thermoregulatory behaviors, causing beriberi-simulating tachypnea, separate from any influence of thiamine deficiency. Read More

View Article
April 2017
8 Reads

Thiamine Assays-Advances, Challenges, and Caveats.

ChemistryOpen 2017 04 8;6(2):178-191. Epub 2017 Mar 8.

Department of Natural Resources Cornell University Ithaca NY 14853 USA.

Thiamine (vitamin B1) is essential to the health of all living organisms and deficiency has long been associated with diseases in animals such as fish, birds, alligators, and domesticated ruminant mammals. Thiamine is also implicated in several human diseases including Alzheimer's, diabetes, dementia, depression and, most notably, Wernicke-Korsakoff syndrome and Beriberi disease. Yet, highly sensitive and specific detection of thiamine remains an analytical challenge, as pM to nm levels of thiamine need to be detected in environmental and human samples, respectively, various phosphorylated variants need to be discriminated, and rapid on-site detection would be highly desirable. Read More

View Article
April 2017
13 Reads

Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis.

J Nat Prod 2017 04 30;80(4):1134-1140. Epub 2017 Mar 30.

Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University , Suwon 16419, Republic of Korea.

Chaenomeles sinensis has been consumed traditionally for the treatment of throat diseases, diarrhea, inflammatory diseases, and dry beriberi. Repeated chromatography of the CHCl-soluble fraction from the 80% MeOH extract of C. sinensis twigs led to the isolation of three new triterpenoids, sinenic acid A (1), 3β-O-cis-feruloyl-2α,19α-dihydroxyurs-12-en-28-oic acid (2), and 3β-O-cis-caffeoylbetulin (3), together with 20 analogues. Read More

View Article
April 2017
5 Reads
1 Citation
3.800 Impact Factor

[Wernicke encephalopathy and dry beriberi; late complications after bariatric surgery performed on a patient with a psychiatric history].

Tijdschr Psychiatr 2017 ;59(2):116-120

A 38-year-old woman was admitted in a psychiatric hospital because of memory disorders. Dry beriberi and Korsakoff's syndrome, as a late neuropsychiatric manifestation of Wernicke's encephalopathy, were established. The beriberi symptoms decreased slowly, but the patient's memory impairments persisted. Read More

View Article
February 2018
6 Reads

Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: A study from northern India.

Indian Heart J 2017 Jan - Feb;69(1):24-27. Epub 2016 Aug 2.

Department of Pediatrics, SKIMS Srinagar, J&K, India. Electronic address:

Objective: To study the effect of thiamine administration on the resolution of pulmonary hypertension in exclusively breastfed infants.

Design: Prospective cohort study.

Setting: Hospital based study of a tertiary care hospital. Read More

View Article
October 2017
18 Reads

Prevalence of clinical thiamine deficiency in individuals with medically complicated obesity.

Nutr Res 2017 Jan 1;37:29-36. Epub 2016 Dec 1.

Center for Advanced Laparoscopic General & Bariatric Surgery, MedStar-Washington Hospital Center and Georgetown University School of Medicine, Washington, DC 20010, USA. Electronic address:

Thiamine is a vitamin whose deficient can result in multiorgan symptoms. We described an 18% prevalence of clinical thiamine deficiency after gastric bypass surgery. Our hypotheses are that individuals with medically complicated obesity frequently have clinical thiamine deficiency and that diabetes mellitus is a mechanism for development of clinical thiamine deficiency. Read More

View Article
January 2017
8 Reads

Thiamine Deprivation Produces a Liver ATP Deficit and Metabolic and Genomic Effects in Mice: Findings Are Parallel to Those of Biotin Deficiency and Have Implications for Energy Disorders.

J Nutrigenet Nutrigenomics 2016 18;9(5-6):287-299. Epub 2017 Feb 18.

Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas UNAM - Instituto Nacional de Pediatría, Mexico City, Mexico.

Thiamine is one of several essential cofactors for ATP generation. Its deficiency, like in beriberi and in the Wernicke-Korsakoff syndrome, has been studied for many decades. However, its mechanism of action is still not completely understood at the cellular and molecular levels. Read More

View Article
November 2017
15 Reads

Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.

Ann Am Thorac Soc 2017 May;14(5):737-741

1 Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.

Rationale: Acute kidney injury (AKI) is common in patients with sepsis and has been associated with high mortality rates. The provision of thiamine to patients with sepsis may reduce the incidence and severity of sepsis-related AKI and thereby prevent renal failure requiring renal replacement therapy (RRT).

Objectives: To test the hypothesis that thiamine supplementation mitigates kidney injury in septic shock. Read More

View Article
May 2017
2 Reads

Commentary: Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge.

Front Nutr 2016 16;3:58. Epub 2017 Jan 16.

Pediatrics, Discipline of Nutrition and Metabolism, Federal University of São Paulo , São Paulo , Brazil.

View Article
January 2017
3 Reads

Beriberi Induced Cardiomyopathy Requiring Salvage Venoarterial Extracorporeal Membrane Oxygenation.

Case Rep Crit Care 2016 5;2016:5043818. Epub 2016 Dec 5.

Advocate Christ Medical Center, Oak Lawn, IL, USA.

Beriberi refers to a constellation of symptoms caused primarily by thiamine (vitamin B1) deficiency. An acute and fulminant presentation of this rare condition has been described in the literature as "Shoshin" beriberi which is characterized by catastrophic cardiovascular collapse. Early recognition and treatment lead to dramatic improvements of symptoms. Read More

View Article
December 2016
2 Reads

A Concise History of Mycotoxin Research.

J Agric Food Chem 2017 Aug 27;65(33):7021-7033. Epub 2016 Dec 27.

Department of Chemistry, Carleton University , Ottawa, Ontario K1S 5B6, Canada.

Toxigenic fungi and mycotoxins entered human food supplies about the time when mankind first began to cultivate crops and to store them from one season to the next, perhaps 10,000 years ago. The storage of cereals probably initiated the transition by mankind from hunter-gatherer to cultivator, at the same time providing a vast new ecological niche for fungi pathogenic on grain crops or saprophytic on harvested grain, many of which produced mycotoxins. Grains have always been the major source of mycotoxins in the diet of man and his domestic animals. Read More

View Article
August 2017
17 Reads

When Was B1, the First Vitamin, Discovered?: An Alternative Perspective.

Authors:
Shozo Sugiura

J Nutr Sci Vitaminol (Tokyo) 2016 ;62(5):372-374

School of Environmental Sciences University of Shiga Prefecture.

View Article
June 2017
5 Reads

[Beriberi 10 years after gastric bypass surgery - case report].

Laeknabladid 2016 Nov;102(11):497-499

Beriberi is primarily related to malnutrition, but also known as a complication following abdominal surgical procedures. A 41 year old woman, who underwent gastric bypass surgery 10 years earlier, presented at the emergency department of Landspitali with general weakness and paresthesia. Physical examination revealed muscle atrophy and attenuated deep tendon reflexes in her lower limbs; presenting as polyneuropathy due to beriberi. Read More

View Article
November 2016
6 Reads

Alcoholic cardiomyopathy : The result of dosage and individual predisposition.

Authors:
B Maisch

Herz 2016 Sep;41(6):484-93

Herz- und Gefäßzentrum Marburg (HGZ) und Philipps Universität Marburg, Feldbergstr. 45, 35043, Marburg, Deutschland.

The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Read More

View Article
September 2016
11 Reads

Perinatal Consumption of Thiamine-Fortified Fish Sauce in Rural Cambodia: A Randomized Clinical Trial.

JAMA Pediatr 2016 Oct 3;170(10):e162065. Epub 2016 Oct 3.

Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia, Canada9South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia10Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia.

Importance: Infantile beriberi, a potentially fatal disease caused by thiamine deficiency, remains a public health concern in Cambodia and regions where thiamine-poor white rice is a staple food. Low maternal thiamine intake reduces breast milk thiamine concentrations, placing breastfed infants at risk of beriberi.

Objective: To determine if consumption of thiamine-fortified fish sauce yields higher erythrocyte thiamine diphosphate concentrations (eTDP) among lactating women and newborn infants and higher breast milk thiamine concentrations compared with a control sauce. Read More

View Article
October 2016
12 Reads

An unusual case of cardiogenic shock in which thiamine administration led to reversal of lactic acidosis and heart function recovery: Shoshin beriberi in an adolescent.

Int J Cardiol 2016 Nov 30;222:401-403. Epub 2016 Jul 30.

Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.

View Article
November 2016
12 Reads

Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge.

Front Nutr 2016 14;3:16. Epub 2016 Jun 14.

Pediatric Team, Medical Department, Médecins Sans Frontières (MSF) , Barcelona , Spain.

In humans, thiamine is a micronutrient prone to depletion that may result in severe clinical abnormalities. This narrative review summarizes current knowledge on thiamine deficiency (TD) and bridges the gap between pathophysiology and clinical presentation by integrating thiamine metabolism at subcellular level with its function to vital organs. The broad clinical spectrum of TD is outlined, with emphasis on conditions encountered in tropical pediatric practice. Read More

View Article
July 2016
8 Reads

Acute Abdominal Pain as a Presenting Symptom of Beriberi in a Pediatric Patient.

J Trop Pediatr 2016 12 20;62(6):490-495. Epub 2016 Jun 20.

Departamento de Pediatria, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP - São Paulo, CP 6109, Brazil

Vitamin B1 (thiamine) plays a fundamental role in the proper functioning of the nervous and cardiovascular systems and in glucose metabolism. Because of the inability of the human body to store large amounts of vitamin, continuous restoration through diet is necessary. In the pediatric population, thiamine deficiency has a broad spectrum of clinical presentations, making diagnosis difficult. Read More

View Article
December 2016
6 Reads

The influence of infantile thiamine deficiency on primary dentition.

Clin Oral Investig 2017 May 17;21(4):1309-1313. Epub 2016 Jun 17.

Pediatric Dental Unit, Barzilai Medical Center, Ashkelon, Israel.

Objectives: The present study explored the histological and chemical effects of infantile thiamine deficiency (ITD) on enamel development through the examination of exfoliated deciduous teeth from a patient who had been fed during his first year of life with a thiamine-deficient milk substitute.

Materials And Methods: Ground sections derived from six exfoliated primary teeth were examined. Slices from a light microscope were photographed for histological analysis. Read More

View Article
May 2017
4 Reads

[Clinical appearance and scalable profile Thiamine deficiency in prison in Guinea: study of thirty-eight observations].

Bull Soc Pathol Exot 2016 May 29;109(2):70-6. Epub 2016 Mar 29.

CHU, Conakry, Guinée.

Cardiovascular and neurological manifestations associated with thiamine deficiency in Guinean prisons are common but not reported.We performed a prospective study of 38 cases related to vitamin B1 deficiency over a period of 4 years. In this population, the literature of traditional data gathered: frequency peak after thirty (92. Read More

View Article
May 2016
9 Reads

Case report: pericardial effusion with constrictive physiology in a patient with wet beriberi.

Nutr J 2016 Apr 8;15:37. Epub 2016 Apr 8.

Disease Control and Homeostasis, Graduate School of Medical Science, Kanazawa, University, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.

Wet beriberi-induced pericardial effusion has rarely been previously described. Little is known about the effect of beriberi-induced pericardial effusion on hemodynamics. Here we present a case of wet beriberi with pericardial effusion that exhibited constrictive physiology, which was dramatically improved after treatment. Read More

View Article
April 2016
4 Reads

Cranial Ultrasonography in Infantile Encephalitic Beriberi: A Useful First-Line Imaging Tool for Screening and Diagnosis in Suspected Cases.

AJNR Am J Neuroradiol 2016 08 7;37(8):1535-40. Epub 2016 Apr 7.

Department of Radiology (N.A.C.), SheriKasmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Background And Purpose: Brain imaging is central to the diagnosis of infantile encephalitic beriberi. Because cranial sonography findings have not been described in infantile encephalitic beriberi, our aim was to investigate its role in the diagnosis of this condition.

Materials And Methods: We performed a retrospective review of head sonography of infants (admitted between November 1, 2014, and March 31, 2015) who presented with encephalopathy. Read More

View Article
August 2016
20 Reads

A simple turn on fluorescent sensor for the selective detection of thiamine using coconut water derived luminescent carbon dots.

Biosens Bioelectron 2016 May 25;79:467-75. Epub 2015 Dec 25.

Interfaces and Nanomaterials Laboratory, Department of Chemical Engineering, National Institute of Technology, Rourkela 769008, India. Electronic address:

In this study microwave-assisted hydrothermal method was used to prepare highly luminescent carbon dots (1-6 nm size) within a minute from tender coconut (Cocos nucifera) water. The synthesized carbon dots (C-dots) exhibit emission of blue and green lights while excited at 390 and 450 nm wavelengths, respectively. As an application, these C-dots were tested for a simple "turn on" fluorescent sensor for rapid detection of thiamine (vitamin B1). Read More

View Article
May 2016
3 Reads

Thiamine deficiency in tachypnoeic Cambodian infants.

Paediatr Int Child Health 2015 ;35(4):312-8

Mayo Medical School.

Background: Beriberi is endemic in South-east Asia. Diagnosis is based on clinical findings, but correlation of clinical features with blood thiamine concentrations is uncertain.

Objectives: To investigate in tachypnoeic Cambodian infants the correlation between whole blood thiamine diphosphate (TDP) concentrations, clinical findings and blood TDP levels after therapy. Read More

View Article
October 2016
13 Reads
4 Citations
0.870 Impact Factor