3,636 results match your criteria Benign and Malignant Soft Tissue Tumors


Cutaneous Scalp Metastases of Malignant Phyllodes Tumor of the Breast.

J Breast Cancer 2020 Jun 27;23(3):320-325. Epub 2020 Feb 27.

Department of Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.

Phyllodes tumor (PT) of the breast is a relatively rare fibroepithelial tumor that accounts for < 1% of primary breast neoplasms. PT is classified histologically as benign, borderline, or malignant, and a malignant PT has greater potential to metastasize than benign PT. Although almost all other organs can be affected, common metastatic sites are the lung and bone via the hematogenous route. Read More

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http://dx.doi.org/10.4048/jbc.2020.23.e18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311367PMC

Accuracy of ultrasound in the characterisation of deep soft tissue masses: a prospective study.

Eur Radiol 2020 Jun 26. Epub 2020 Jun 26.

Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.

Purpose: To investigate the accuracy of ultrasound in characterising the type of mass and likelihood of malignancy in deep soft tissue masses.

Methods: Five hundred seventy-nine deep soft tissue masses were prospectively studied by ultrasound. Masses (n = 137) with prior MRI or CT were not included. Read More

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http://dx.doi.org/10.1007/s00330-020-07002-5DOI Listing

Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review.

Medicine (Baltimore) 2020 Jun;99(26):e20869

Director of Vietnam Military Medical University, Hanoi, Vietnam.

Rationale: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solitary well-circumscribed lung parenchymal lesion, and is often located in juxtapleural or juxtafissural positions. Read More

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http://dx.doi.org/10.1097/MD.0000000000020869DOI Listing

Tumorous conditions of the pediatric hand and wrist: Ten-year experience of a single center.

Jt Dis Relat Surg 2020 18;31(2):341-345. Epub 2020 Jun 18.

Akdeniz Üniversitesi Tıp Fakültesi Ortopedi ve Travmatoloji Kliniği, 07070 Kampüs, Antalya, Türkiye.

Objectives: This study aims to evaluate the distribution and prevalence of pediatric hand tumors and tumor-like lesions according to age and gender.

Patients And Methods: We retrospectively examined the details of hospital records of 646 patients who were operated for hand mass between January 2009 and January 2019 and whose pathological diagnosis was established in the same hospital. A total of 54 patients (18 males, 36 females; mean age 12. Read More

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http://dx.doi.org/10.5606/ehc.2020.74972DOI Listing

Benign Infiltrative Myofibroblastic Neoplasms of Childhood with USP6 Gene Rearrangement.

Histopathology 2020 Jun 24. Epub 2020 Jun 24.

Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.

Background: Several morphologically overlapping (myo)fibroblastic neoplasms harbor USP6 rearrangements, including aneurysmal bone cyst, nodular fasciitis, myositis ossificans, cranial fasciitis, fibro-osseous pseudotumor of digits, and cellular fibroma of tendon sheath. USP6-induced neoplasms are almost universally benign and cured by local excision.

Design: Three deep-seated, radiographically aggressive and rapidly growing childhood myofibroblastic neoplasms were morphologically and molecularly characterized by USP6 break-apart fluorescence in situ hybridization (FISH), transcriptome sequencing, and targeted capture analysis. Read More

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http://dx.doi.org/10.1111/his.14182DOI Listing

Spinal manifestations of Neurofibromatosis type 1.

Childs Nerv Syst 2020 Jun 20. Epub 2020 Jun 20.

The Gilbert Israeli International Neurofibromatosis Center (GIINFC), Tel Aviv, Israel.

Background: Neurofibromatosis type 1 (NF1) patients may present a wide spectrum of spinal pathologies. Osseous changes may lead to severe deformities with significant implications on growth and quality of life. Neurogenic tumors and soft tissue abnormalities may cause neuropathic pain and dysfunction ranging from minor paresthesias to profound motor and sensory deficits. Read More

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http://dx.doi.org/10.1007/s00381-020-04754-9DOI Listing

Dedifferentiated liposarcoma of the spermatic cord: Case report and review of literature.

Int J Surg Case Rep 2020 Jun 12;72:418-422. Epub 2020 Jun 12.

Department of Urology, Kendall Regional Medical Center, Miami, FL, USA.

Introduction: Malignant spermatic cord tumors have an annual incidence of 0.3 cases/million. The vast majority of tumors in this region are benign. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.06.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306526PMC

Role of high-resolution ultrasound in detection and monitoring of peripheral nerve tumor burden in neurofibromatosis in children.

Childs Nerv Syst 2020 Jun 19. Epub 2020 Jun 19.

Department of Neurology and Hertie Institute for Clinical Brain Research (HIH), University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.

Purpose: Peripheral nerve sheath tumors are hallmark findings in neurofibromatosis types 1 and 2. With increasing size, they typically lead to neurological symptoms, and NF1 patients have a lifetime risk of 8-13% for developing malignant peripheral nerve sheath tumors. Medical imaging is therefore highly needed for early detection and exact localization of symptomatic or potentially malignant tumors. Read More

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http://dx.doi.org/10.1007/s00381-020-04718-zDOI Listing

Cytomorphological spectrum of hand, wrist, and foot lesions at tertiary care center in central India.

Diagn Cytopathol 2020 Jun 19. Epub 2020 Jun 19.

Department of Pathology & Lab Medicine, All India Institute of Medical Sciences, Bhopal, India.

Background: Fine-needle aspiration cytology (FNAC) being a fast technique is used as a primary investigation to diagnose wide spectrum of hand, wrist, and foot lesions. These sites are prone to trauma, reparative, and infectious process, which forms mass lesions mimicking neoplasia. Our study highlighted the importance of FNAC with the chance of reduction in biopsy or excision. Read More

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http://dx.doi.org/10.1002/dc.24528DOI Listing

Granular Cell Tumor Breast Masquerading as a Malignancy Cytologically: a Rare Case Presenting a Diagnostic Dilemma.

Indian J Surg Oncol 2020 Jun 26;11(2):321-324. Epub 2020 Mar 26.

Department of Surgery, ESIC Medical College, Faridabad, Haryana India.

Granular cell tumor (GCT) also known as Abrikossoff's tumor is an uncommon soft tissue tumor of neurogenic origin. GCT of the breast accounts for < 0.1% of breast tumors and 6% of all reported cases of granular cell tumor. Read More

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http://dx.doi.org/10.1007/s13193-020-01055-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260310PMC

Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment.

J Clin Med 2020 Jun 5;9(6). Epub 2020 Jun 5.

Department of Dermatology, Cleveland Clinic, Cleveland, OH 44195, USA.

Dermatofibrosarcoma protuberans (DFSP) is a slow growing, low- to intermediate-grade dermal soft-tissue tumor. It has a high local recurrence rate but low metastatic potential. It is characterized by a uniform spindle cell arrangement, classically with a storiform pattern and CD34 immunoreactivity. Read More

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http://dx.doi.org/10.3390/jcm9061752DOI Listing

Magnetic resonance imaging semantic and quantitative features analyses: an additional diagnostic tool for breast phyllodes tumors.

Am J Transl Res 2020 15;12(5):2083-2092. Epub 2020 May 15.

Department of Bone and Soft Tissue Tumors, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer Tianjin, P. R. China.

Objective: This study aimed to differentiate benign and non-benign (borderline/malignant) phyllodes tumors of the breast by the semantic and quantitative features in magnetic resonance imaging (MRI).

Methods: The female patients, diagnosed with phyllodes tumors by MRI and pathological test, were retrospectively selected from December, 2006 to April, 2019. The MRI of benign, borderline and malignant phyllodes tumors was analyzed using 8 semantic features and 20 computed quantitative features from diffuse contrast-enhanced magnetic resonance imaging (DCE-MRI). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270016PMC
May 2020
3.226 Impact Factor

The diagnostic value of ultrasound and shear wave elastography in the differentiation of benign and malignant soft tissue tumors.

Skeletal Radiol 2020 Jun 6. Epub 2020 Jun 6.

Department of Pathology, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey.

Aim: To evaluate the diagnostic value of ultrasound (US) and shear wave elastography (SWE) in the differentiation of benign and malignant soft tissue tumors.

Materials And Methods: A hundred and nine patients (mean age 43.3 ± 20. Read More

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http://dx.doi.org/10.1007/s00256-020-03492-yDOI Listing

Lipoma in the pronator quadratus: A case report.

Medicine (Baltimore) 2020 May;99(21):e20248

Hand Surgery, the Second Hospital of Jilin University, No. 218, Lane Ziqiang, Nanguan District, Changchun City, Jilin.

Rationale: Lipomas are common benign tumors, constituting 16% of soft tissue mesenchymal tumors. They usually occur under the skin or in the large muscles of the thigh, shoulder, or upper arm. There are few reported cases of lipomas located in the forearm and hand muscles, accounting for less than 1% of all lipomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000020248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249885PMC
May 2020
5.723 Impact Factor

Does Osteoarticular Allograft Reconstruction Achieve Long-term Survivorship after En Bloc Resection of Grade 3 Giant Cell Tumor of Bone?

Clin Orthop Relat Res 2020 May 26. Epub 2020 May 26.

J. I. Albergo, G. L Farfalli, A Cabas-Geat, P. Roitman, M. A. Ayerza, L. A. Aponte-Tinao, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Background: En bloc resection of benign tumors is only indicated in aggressive lesions with substantial destruction of the affected bone. Few reports have evaluated the long-term outcome of Grade 3 giant cell tumor of bone (GCTB; defined as severe bone destruction and soft tissue extension) treated with en bloc resection and reconstruction with a massive allograft. We recently reported that patients with benign tumors achieved better allograft reconstruction survivorship compared with those treated for a malignant bone tumor. Read More

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http://dx.doi.org/10.1097/CORR.0000000000001337DOI Listing

Unexpected tumor-to-tumor metastasis of synovial sarcoma within leiomyoma: A case report and literature review.

J Obstet Gynaecol Res 2020 May 25. Epub 2020 May 25.

Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

A tumor metastasis within another tumor is known as tumor-to-tumor metastasis (TTM). We report a 43-year-old woman who presented with hypermenorrhea and an abdominal mass. She had history of a soft tissue tumor on her left ankle at 38 years of age. Read More

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http://dx.doi.org/10.1111/jog.14298DOI Listing

[Clinical and pathological analysis of 64 patients with primary neoplasms of the lacrimal drainage system].

Zhonghua Yan Ke Za Zhi 2020 May;56(5):364-369

Tianjin Eye Hospital, Tianjin Key Lab. of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Institute, Tianjin 300020, China.

To analyze the pathological classification and age distribution of primary neoplasms of the lacrimal drainage system. Retrospective case series study. A total of 64 patients (65 eyes) were diagnosed with primary neoplasms of the lacrimal drainage system and received surgery at Tianjin Eye Hospital from January 2006 to December 2016. Read More

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http://dx.doi.org/10.3760/cma.j.cn112142-20190414-00216DOI Listing

Soft Tissue Tumors of the Abdomen and Retroperitoneum.

Surg Clin North Am 2020 Jun 15;100(3):649-667. Epub 2020 Apr 15.

Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, 550 Peachtree Street, Northeast, 9th Floor, Suite 900, Atlanta, GA 30308, USA. Electronic address:

Soft tissue tumors of the abdomen and retroperitoneum encompass a wide range of benign and malignant neoplasms. Retroperitoneal sarcomas, the most common, are composed of rare malignancies with numerous histiotypes. Surgery remains the cornerstone of treatment and the only curative option for retroperitoneal sarcomas. Read More

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http://dx.doi.org/10.1016/j.suc.2020.02.011DOI Listing

Point-of-Care Ultrasound for Evaluating Lymphadenopathy in the Pediatric Emergency Department: Case Series and Review of Literature.

J Emerg Med 2020 Apr 27. Epub 2020 Apr 27.

Children's Emergency, KK Women's and Children's Hospital Pte. Ltd., Singapore.

Background: Children present to the pediatric emergency department (ED) with enlarged lymph nodes due to a broad spectrum of conditions ranging from benign causes like reactive lymph nodes to adverse conditions like malignancy. Identifying sonographic features typical of infection, inflammation, and neoplasms will help assist clinicians in deciding the disposition of the patients from the ED. Point-of-care ultrasound has become an essential adjunct for diagnostic assessment in pediatric emergency medicine. Read More

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http://dx.doi.org/10.1016/j.jemermed.2020.03.026DOI Listing

F18-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of vertebral vascular tumors.

Clin Imaging 2020 Apr 18;65:24-32. Epub 2020 Apr 18.

Department of Nuclear Medicine, Peking University Third Hospital, 100191 Beijing, PR China. Electronic address:

Purpose: The uptake of F-FDG is higher in most malignancies than in benign tumors. This study aimed to investigate the diagnostic value of F-FDG PET/CT in vertebral vascular tumors.

Materials And Methods: We retrospectively collected PET/CT and clinical data of patients with vertebral vascular tumors and analyzed the location, number, and bone destruction and FDG uptake features of the lesion. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.03.019DOI Listing

Superficial malignant ossifying fibromyxoid tumors harboring the rare and recently described ZC3H7B-BCOR and PHF1-TFE3 fusions.

J Cutan Pathol 2020 Apr 30. Epub 2020 Apr 30.

Division of Molecular Pathology, The Translational Genomics Research Institute, Phoenix, Arizona.

Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue neoplasm of uncertain differentiation and intermediate biologic potential. Up to 85% of OFMTs, including benign, atypical and malignant forms, harbor fusion genes. Most commonly, the PHF1 gene localized to 6p21 is fused with EP400, but other fusion partners such as MEAF6, EPC1, and JAZF1 have also been described. Read More

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http://dx.doi.org/10.1111/cup.13728DOI Listing

Ectopic breast tissue presenting as an enlarging abdominal mass.

Radiol Case Rep 2020 Jun 8;15(6):733-740. Epub 2020 Apr 8.

Division of Musculoskeletal Imaging, Radiology Department, Nuffield Orthopaedic Centre, Oxford, UK.

Ectopic breast tissue (EBT) is an uncommon entity that occurs in about 6% of the population, more frequently in Asian people. It manifests as a nonspecific soft tissue mass that can develop in any location along the "milk-line," with the axilla being the most frequently reported location. As with normal breast tissue, both benign and malignant processes can arise from EBT. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.02.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152596PMC

<Editors' Choice> mRNA expression in soft-tissue tumors.

Nagoya J Med Sci 2020 Feb;82(1):85-92

Division of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Stanniocalcin-1 () is a glycoprotein that was originally identified as a calcium-regulating hormone in bony fish, and that has been shown to also critically mediate cell growth, proliferation and differentiation, etc. in humans. Increased expression levels have been previously detected in different human cancer samples, such as those isolated from lung, breast, ovary, colon, pancreas, and liver tumors; thus, the present study evaluated expression in various soft-tissue tumors. Read More

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http://dx.doi.org/10.18999/nagjms.82.1.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103862PMC
February 2020

Battle Against Musculoskeletal Tumors: Descriptive Data of Military Hospital Experience.

Front Public Health 2020 25;8:97. Epub 2020 Mar 25.

Department of Orthopaedics and Traumatology, Gulhane Training and Research Hospital, Ankara, Turkey.

Management of musculoskeletal tumors remains challenging for orthopedic surgeons. The aim of this cross-sectional study was to present the prevalence and localization of musculoskeletal disorders diagnosed and treated at a tertiary referral military hospital. A total of 552 patients' medical records who presented to our clinic between 2009 and 2014 with the diagnosis of musculoskeletal tumors were retrospectively analyzed according to age, gender, bone/soft tissue localization, histopathological diagnosis, incidence, and treatment. Read More

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http://dx.doi.org/10.3389/fpubh.2020.00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109251PMC

[Application of 3D computer-assisted printing technique combined with plastic titanium mesh in the reconstruction of maxillary defect].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Mar;55(3):200-204

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine; Ear Institute, Shanghai JiaoTong University School of Medicine; Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases, Shanghai 200011, China.

To investigate the application and clinical outcomes of using 3D computer-assisted printing technique combined with plastic titanium mesh in the reconstruction of maxillary defect. Clinical data of 14 patients in Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital from January 2016 to June 2018, who were treated for partial or total removal of the maxilla due to benign or malignant tumors and those acquired maxillary defects caused by severe compound trauma were analyzed retrospectively. Twelve males and 2 females were included, with the age ranging from 16 to 51 years old. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2020.03.003DOI Listing

[Individualised Multimodal Therapy of Retroperitoneal Soft Tissue Sarcomas].

Authors:
Markus Ghadimi

Zentralbl Chir 2020 Apr 8;145(2):140-147. Epub 2020 Apr 8.

Allgemein-, Viszeral-, Tumor- und Transplantationschirurgie, Uniklinik Köln, Deutschland.

Retroperitoneal soft tissue sarcomas make up a diverse group of malignant tumours of mesenchymal origin with diverse histo- and molecular pathology. Liposarcoma and leiomyosarcoma are the predominant subentities - followed by the substantially less frequent solitary fibrous tumors, malignant peripheral nerve-sheath tumors and unclassified pleomorphic sarcomas. The biological behaviour of retroperitoneal soft tissue sarcomas is highly variable, depending on the histopathological subtype. Read More

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http://dx.doi.org/10.1055/a-1117-4043DOI Listing

Chondromyxoid Fibroma of Distal Phalanx of the Great Toe: A Rare Clinical Entity.

Cureus 2020 Feb 28;12(2):e7133. Epub 2020 Feb 28.

Orthopaedics, Siddhartha Medical College, Vijayawada, IND.

Chondromyxoid fibroma is a rare benign tumor of cartilaginous origin with myxoid and fibrous components. It accounts for approximately 1% of bone tumors. Metaphysis of long bones is the most common location of this tumor. Read More

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http://dx.doi.org/10.7759/cureus.7133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105257PMC
February 2020

MRI of Rhabdomyosarcoma and Other Soft-Tissue Sarcomas in Children.

Radiographics 2020 May-Jun;40(3):791-814. Epub 2020 Apr 3.

From the Departments of Diagnostic Imaging (E.J.I.C., M.N., I.B.M.d.l.T., J.M.d.C.), Pathology (M.S.), Orthopaedics (F.T.), and Oncology and Haematology (M.G.), Hospital Sant Joan de Déu, Av Sant Joan de Déu 2, 08950 Esplugues de Llobregat (Barcelona), Spain; Department of Medical Imaging, University of Toronto, Toronto, Ont, Canada (O.M.N.); and Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Ont, Canada (O.M.N.).

Soft-tissue sarcomas in children comprise a heterogeneous group of entities with variable manifestation depending on the age of the patient and the location of the tumor. MRI is the modality of choice for evaluating musculoskeletal soft-tissue tumors and plays a paramount role in both initial diagnosis and assessment of tumor response during and after treatment. Conventional MRI sequences, such as T1- and T2-weighted imaging, offer morphologic information, which is important for localizing the lesion and describing anatomic relationships but not accurate for determining its malignant or benign nature and may be limited in differentiating tumor response from therapy-related changes. Read More

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http://dx.doi.org/10.1148/rg.2020190119DOI Listing

Shoulder Tumor/Tumor-Like Lesions: What to Look for.

Magn Reson Imaging Clin N Am 2020 May;28(2):301-316

Department of Radiology, University of California San Diego, School of Medicine, UCSD Teleradiology and Education Center, 408 Dickinson Street, Mail Code #8226, San Diego, CA 92103-8226, USA.

This article discusses the most common tumor and tumor-like lesions arising at the shoulder. Osseous tumors of the shoulder rank second in incidence to those at the knee joint and include benign osteochondromas and myeloma or primary malignant lesions, such as osteosarcoma or chondrosarcomas. Soft tissue tumors are overwhelmingly benign, with lipomas predominating, although malignant lesions, such as liposarcomas, can occur. Read More

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http://dx.doi.org/10.1016/j.mric.2019.12.011DOI Listing

Benign and Malignant Granular Cell Tumor of the Hypopharynx: Two Faces of a Rare Entity.

Head Neck Pathol 2020 Apr 2. Epub 2020 Apr 2.

University of Miami Hospital, Miller School of Medicine, 1400 NW 12th Avenue, Room 4078, Miami, FL, 33136, USA.

Granular cell tumors (GCT) are rare soft tissue tumors that involve the head and neck in 50% of patients. Two distinct variants of GCT, one benign (bGCT) and the other malignant (mGCT), involving the hypopharynx, a subsite of the larynx, are presented here. The clinical presentations, radiographic features, pathologic diagnosis in these two variants of GCT are discussed. Read More

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http://dx.doi.org/10.1007/s12105-020-01157-9DOI Listing

Subtotal Exenteration of the Orbit for Benign Orbital Disease.

J Craniofac Surg 2020 Mar 27. Epub 2020 Mar 27.

Department of Ophthalmology.

Purpose: Total exenteration of the orbit with removal of the eye globe and surrounding tissues is most frequently indicated for malignant tumors. The indications for exenteration of the orbit for benign orbital lesion are rare. Not adequately treated infection of the orbit by systemic antibiotics can lead to destructive changes of soft tissues in the region of the orbit and partial exenteration with eyelid sparing technique is necessary. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006357DOI Listing

F-FDG PET/CT imaging features of lipomatous tumors.

Am J Nucl Med Mol Imaging 2020 25;10(1):74-82. Epub 2020 Feb 25.

Department of Radiology, Mayo Clinic Rochester, MN 55905, US.

The objective was to evaluate the F-FDG PET/CT characteristics of lipomatous tumors, and examine features helpful in differentiating benign from malignant tumor subtypes. Patients undergoing F-FDG PET/CT from 01/2005 to 03/2018 with subsequent pathologically confirmed liposarcoma, lipoma, or hibernoma were retrospectively reviewed with IRB approval. A variety of imaging features, including metabolic activity and tumor morphology were noted. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076300PMC
February 2020

Mixed malignant peripheral nerve sheath tumor in the inguinal region: a case report.

Int J Clin Exp Pathol 2020 1;13(2):261-265. Epub 2020 Feb 1.

Department of Pathology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University Yantai, China.

Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant soft tissue tumor that accounts for approximately 5% of all soft tissue sarcomas. This tumor originates from the peripheral nerves and occurs mainly in the limbs, head and neck, and spine. As a more aggressive tumor, it has higher recurrence and metastasis rates, and patient prognosis is poor. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061797PMC
February 2020

Clinical significance of thermal detection of soft-tissue tumors.

Int J Clin Oncol 2020 Mar 21. Epub 2020 Mar 21.

Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-ku, Osaka, 545-8585, Japan.

Background: Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of soft-tissue tumors. Read More

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http://dx.doi.org/10.1007/s10147-020-01658-1DOI Listing

Malignant peripheral nerve sheath tumor: A rare malignancy.

J Oral Maxillofac Pathol 2020 Feb 28;24(Suppl 1):S86-S90. Epub 2020 Feb 28.

Department of OMR, Dhulikhel Hospital, Kathmandu University, School of Medical Sciences, Nepal.

Malignant peripheral nerve sheath tumor (MPNST) is also termed as spindle cell malignancy of the peripheral nerve Schwann cell. It is a rare and highly aggressive, soft-tissue sarcoma of ectomesenchymal origin that accounts for 10% of all sarcomas and only 10%-12% of all lesions occur in the head-and-neck region, thus making it a rare entity. It arises or from the preexisting benign neurofibroma. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_9_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069146PMC
February 2020

Prediction of Soft Tissue Sarcoma from Clinical Characteristics and Laboratory Data.

Cancers (Basel) 2020 Mar 13;12(3). Epub 2020 Mar 13.

Department of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

The accurate diagnosis of soft tissue tumors may be difficult. Simple clinical characteristics or laboratory data that can predict tumor malignancy can be useful tools for diagnosing soft tissue tumors. Between 2003 and 2018, 588 patients with primary soft tissue tumors were retrospectively reviewed. Read More

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http://dx.doi.org/10.3390/cancers12030679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140089PMC

Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors.

J Orthop Surg Res 2020 Mar 11;15(1):103. Epub 2020 Mar 11.

Department of Ultrasound, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.

Background: To explore the feasibility to identify malignant musculoskeletal soft tissue tumors using real-time shear wave elastography (rtSWE).

Methods: One hundred fifteen musculoskeletal soft tissue tumors in 92 consecutive patients were examined using both conventional ultrasonography (US) and rtSWE. For each patient, the rtSWE parameters including maximum elasticity (E), mean elasticity (E), minimum elasticity (E), standard deviation of the elasticity (E), and rtSWE image pattern were obtained. Read More

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http://dx.doi.org/10.1186/s13018-020-01620-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066781PMC

Can Strain Elastography Predict Malignancy of Soft Tissue Tumors in a Tertiary Sarcoma Center?

Diagnostics (Basel) 2020 Mar 7;10(3). Epub 2020 Mar 7.

Department of Diagnostic Radiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen OE, Denmark.

This study aims to investigate the ability of ultrasound strain elastography as an adjunct to predict malignancy in soft tissue tumors suspect of sarcoma or metastasis in a tertiary reference center for sarcoma. A total of 137 patients were included prospectively. Patients were referred on the basis of clinical or radiological suspicion of malignant soft tissue tumor. Read More

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http://dx.doi.org/10.3390/diagnostics10030148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151207PMC

Histopathology of parasellar neoplasms.

Neuroendocrinology 2020 Mar 11. Epub 2020 Mar 11.

The anatomical and histological complexity of the parasellar region, as well as the presence of embryonic remnants, determine the huge diversity of parasellar neoplasms. Some of them are only located in the parasellar region, whereas others can occur elsewhere, within or outside the central nervous system. Their spectrum ranges from histologically benign and low grade malignant to high-grade malignant tumours. Read More

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http://dx.doi.org/10.1159/000507084DOI Listing

Outcome of patients with primary retroperitoneal solitary fibrous sarcoma.

Int J Clin Oncol 2020 May 5;25(5):921-928. Epub 2020 Mar 5.

Department of Bone and Soft Tissue Sarcomas, Fudan University Shanghai Cancer Center, No. 270 Dongon Road, Shanghai, China.

Background: To describe the clinicopathological features of primary retroperitoneal solitary fibrous tumor (RSFT) and define the prognostic factors.

Methods: The comprehensive data of 35 primary RSFT patients who got curative surgery at a tertiary cancer center from April 2004 to October 2018 were retrospectively analyzed.

Results: Male patients outnumbered female patients (19 vs. Read More

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http://dx.doi.org/10.1007/s10147-020-01617-wDOI Listing

Proliferative Fasciitis of the Hand in a Nine-Year-Old Girl: A Case Report and Review of the Literature.

Cureus 2020 Jan 24;12(1):e6763. Epub 2020 Jan 24.

Radiology, Queen Fabiola Children's University Hospital, Brussels, BEL.

Proliferative fasciitis (PF) of the hand is a rare condition, which typically occurs in adulthood. To date, only two dozen cases of PF have been reported in children. This benign condition can mimic malignant soft tissue tumors such as soft tissue sarcoma. Read More

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http://dx.doi.org/10.7759/cureus.6763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039357PMC
January 2020

Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis.

J Indian Assoc Pediatr Surg 2020 Mar-Apr;25(2):85-90. Epub 2020 Jan 28.

Department of Pediatric Surgery, PGIMER, Chandigarh, India.

Aims: Neonatal tumors (NTs) include a group of diverse neoplasms. In this study, we reviewed our data for clinical presentations, management options, and outcome.

Materials And Methods: All patients from 0- to 1-month age presenting with solid tumors, from 2006 to 2018 were studied. Read More

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http://dx.doi.org/10.4103/jiaps.JIAPS_241_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020687PMC
January 2020

5-Aminolevulinic acid tumor paint and photodynamic therapy for myxofibrosarcoma: an in vitro study.

J Orthop Surg Res 2020 Mar 5;15(1):94. Epub 2020 Mar 5.

Department of Orthopaedic Surgery and Oncology, The Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, MD, 21287, USA.

Background: 5-Aminolevulinic acid (5-ALA), a fluorescent contrast agent, has been used for tumor paint and photodynamic therapy (PDT) for various tumors, but its use with soft tissue sarcomas is not well documented. Myxofibrosarcoma, a subtype of soft tissue sarcoma with a high local recurrence rate, may benefit from similar types of treatment. The purpose of this study was to analyze the effects of 5-ALA tumor paint and PDT on a myxofibrosarcoma cell line. Read More

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http://dx.doi.org/10.1186/s13018-020-01606-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059315PMC

Preoperative MRI-Based Radiomic Machine-Learning Nomogram May Accurately Distinguish Between Benign and Malignant Soft-Tissue Lesions: A Two-Center Study.

J Magn Reson Imaging 2020 Feb 29. Epub 2020 Feb 29.

Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Background: Preoperative differentiation between malignant and benign soft-tissue masses is important for treatment decisions.

Purpose/hypothesis: To construct/validate a radiomics-based machine method for differentiation between malignant and benign soft-tissue masses.

Study Type: Retrospective. Read More

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http://dx.doi.org/10.1002/jmri.27111DOI Listing
February 2020
3.210 Impact Factor

Biphasic synovial Sarcoma with extensive calcification in the temporomandibular joint region: A rare case report and literature review.

J Stomatol Oral Maxillofac Surg 2020 Feb 25. Epub 2020 Feb 25.

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei_MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China; Oral Histopathology Department, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China. Electronic address:

Introduction: Synovial sarcoma (SS) is a malignant soft-tissue sarcoma primarily affecting the lower extremities of young adults. Synovial sarcoma occurring in the head and neck region is rare.

Observation: We report a case of a 32-year-old female with a biphasic synovial sarcoma, showing extensive calcification, arising in the temporomandibular joint (TMJ). Read More

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http://dx.doi.org/10.1016/j.jormas.2020.02.005DOI Listing
February 2020

Small indeterminate superficial soft tissue masses: relationship between depth and histological grade.

Br J Radiol 2020 Jun 6;93(1110):20191037. Epub 2020 Mar 6.

Department of Radiology, Royal National Orthopaedic Hospital, Stanmore, UK.

Objective: To determine whether the location of a small, indeterminate soft tissue mass within the subcutaneous compartment is related to its histological grade.

Methods: All Sarcoma Service referrals over a 12 month period of small (<3 cm) superficial soft tissue masses, indeterminate by MRI evaluation which subsequently underwent primary excision biopsy were included. Lesions were categorised by their anatomical location in the subcutaneous compartment. Read More

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http://dx.doi.org/10.1259/bjr.20191037DOI Listing

[Metastatic leiomyoma or synchronous lesion of the uteri corpus and vulva?]

Arkh Patol 2020 ;82(1):62-67

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia.

Objective: To reveal the morphological characteristics of simultaneously diagnosed leiomyoma of the corpus uteri and vulva.

Subject And Methods: The paper describes a case of multiple uterine leiomyomas concurrent with vulvar leiomyoma in a 39-year-old patient with progressive tumor nodule growth over 2 years. Vulvar tumor was biopsied simultaneously with extirpation of the uterus; vulvar leiomyoma was removed six months later. Read More

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http://dx.doi.org/10.17116/patol20208201162DOI Listing
February 2020

Glomangioma of Uncertain Malignant Potential: A Case Report.

Case Rep Orthop 2020 8;2020:4237076. Epub 2020 Jan 8.

Department of Orthopedics, Cedars Sinai Medical Center, Los Angeles, CA, USA.

Glomus tumors are rare benign tumors which commonly affect the hand but are seldom seen extradigitally. Less commonly seen is the glomangioma, a variant of benign glomus tumor, and even rarer is the glomangiosarcoma, a malignant variant. Determining malignancy can be difficult and an intermediate diagnosis, glomus tumor of uncertain malignant potential, has been proposed. Read More

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http://dx.doi.org/10.1155/2020/4237076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975219PMC
January 2020

Skin and Soft Tissue Lesions in a District Hospital in Central Nigeria: A Histopathological Study.

Dermatol Res Pract 2019 26;2019:8143680. Epub 2019 Dec 26.

Department of Pathology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

. Skin and soft tissue diseases form a large and heterogeneous group of mesenchymal extraskeletal and dermatologic lesions in humans. Diseases of the skin and soft tissue can develop virtually anywhere in the body, extremities, the trunk, the retroperitoneum, the head, and the neck. Read More

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http://dx.doi.org/10.1155/2019/8143680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012205PMC
December 2019

The Imaging Spectrum of Synovial Sarcomas: A Pictorial Review From a Single-Centre Tertiary Referral Institution.

Can Assoc Radiol J 2020 Feb 18:846537119899284. Epub 2020 Feb 18.

Department of Medical Imaging, London Health Sciences Centre, University Hospital, London, Ontario, Canada.

Synovial sarcomas are malignant soft-tissue tumors that typically affect young patients. They can arise from nearly anywhere in the body, most commonly the extremities, head and neck, and thorax. The imaging features are highly variable and depend on the anatomic origin. Read More

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http://dx.doi.org/10.1177/0846537119899284DOI Listing
February 2020