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Auris Nasus Larynx 2022 May 16. Epub 2022 May 16.

Shigeno Otolaryngology Vertigo-Hearing Impairment Clinic, 1-21 Ougi-machi, Nagasaki 852-8132, Japan. Electronic address:

Objective: Otolithic dysfunction is investigated in cases of direction-changing horizontal positional nystagmus (DCHPN) due to peripheral vestibular disorders.

Methods: The static-subjective visual vertical (S-SVV) was conducted in DCHPN cases within 48 h after onset.

Results: The absolute values of S-SVV deviations of patients with Light cupula and lateral canal-benign paroxysmal positional vertigo-cupulolithiasis (L-BPPV-Cup) were significantly different from those of healthy subjects (p < 0. Read More

Contrast Media Mol Imaging 2022 26;2022:8952355. Epub 2022 Apr 26.

Department of Neurology, Baoji City People's Hospital, Baoji 721000, Shaanxi, China.

This research aimed to discuss the characteristics of benign paroxysmal positional vertigo (BPPV) and the correlation with cerebrovascular disease. An artificial intelligence algorithm under a parallel dual-domain concatenated convolutional neural network (PDDC-CNN) was proposed to process the images of magnetic resonance imaging (MRI). MRI, magnetic resonance angiography (MRA), and susceptibility weighted imaging (SWI) were performed on all 60 research objects with a 3. Read More

Clin Oral Implants Res 2022 May 16. Epub 2022 May 16.

Private Practice, Roma, Italy.

Objective: Clinical indications for maxillary sinus floor elevation with transcrestal techniques have increased in recent years even in sites with minimal residual bone height (RBH). Nevertheless, limited information is currently available on incidence of intraoperative complications and early implant failure in these cases.

Material And Methods: This retrospective multicenter study was performed on anonymized clinical and radiographic records of patients who underwent transcrestal sinus floor elevation in seven clinical centers. Read More

Am J Otolaryngol 2022 May 6;43(4):103474. Epub 2022 May 6.

Vestibology & ENT Unit, Giovanni Paolo II Hospital, Policoro, Matera, Italy.

Purpose: The diagnosis of benign paroxysmal positional vertigo (BPPV) involving the posterior semicircular canal (PSC) is traditionally entrusted to positioning tests where patients are rapidly brought in the supine position. This prospective study aims to define the role of a diagnostic protocol for PSC-BPPV including only upright tests.

Materials And Methods: 109 patients with PSC-BPPV were enrolled. Read More

Laryngoscope 2022 May 7. Epub 2022 May 7.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.

Objectives: This study aimed to determine the clinical characteristics of benign paroxysmal positional vertigo (BPPV) in young children.

Study Design: Retrospective case review.

Methods: All children <10 years old that have been diagnosed with BPPV at our pediatric vestibular program between December 2012-July 2021 were selected. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 Apr;36(4):285-288

Department of Otolaryngology，Vertigo Clinic Treatment Center，the First Affiliated Hospital of Dalian Medical University，Dalian，116000，China.

To investigate the difference between manual reduction and automatic device reduction in the treatment of benign paroxysmal positional vertigo（BPPV）, and to provide evidence-based medicine for the clinical choice of BPPV treatment. Two hundred and two BPPV patients who came to the hospital for diagnosis and treatment were collected and divided into two groups by random number table method. Group A had 102 cases for manual reduction, and group B had 100 cases for automatic device reduction. Read More

Front Neurol 2022 12;13:828642. Epub 2022 Apr 12.

Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Objectives: The purpose of this study was to apply the amplitude of the low-frequency fluctuation (ALFF) method to investigate the spontaneous brain activity alterations in patients with residual dizziness (RD) after successful canalith repositioning manoeuvre for benign paroxysmal positional vertigo (BPPV).

Methods: All BPPV patients underwent visual vertigo analog scale (VVAS) evaluations and functional magnetic resonance imaging (fMRI). The ALFF method was used to assess the spontaneous brain activity. Read More

Acta Otolaryngol 2022 May 1:1-7. Epub 2022 May 1.

Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjyu, Tokyo.

Background: Gufoni maneuver is known to be effective for horizontal canal benign positional vertigo (HC-BPPV), but there are some intractable patients that the treatment procedure does not work.

Objective: The clinical outcomes of patients with HC-BPPV were investigated. We also investigated the characteristics of intractable patients which needed long time to the remission. Read More

Eur Arch Otorhinolaryngol 2022 Apr 23. Epub 2022 Apr 23.

Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India.

Background And Objectives: BPPV (benign paroxysmal positional vertigo) is a syndrome marked by brief bouts of vertigo accompanied by rapid changes in head position. Recent ongoing therapeutic approaches used are vestibular rehabilitation exercises and physical maneuvers like the Epley maneuver, Semont maneuver. Gans repositioning maneuver (GRM) is a new hybrid maneuver, consisting of safe and comfortable series of postures that can be conveniently applied on patients with any spinal pathology or even in elderly. Read More

Diagnostics (Basel) 2022 Apr 15;12(4). Epub 2022 Apr 15.

Division of General Surgery, Department of Surgery, E-Da Cancer Hospital, Kaohsiung 82445, Taiwan.

To date, along with the progress of new technology and computer program development, the high-resolution computed tomography (HRCT) had been applied in different clinical application, such as HRCT for coronary angiography. In the current neuroimaging reports, we present HRCT images of the head/neck of two cases, in which one had a diagnosis of benign paroxysmal positional vertigo (BPPV) and the other did not, to represent the Tyndall effect, which describes the scattering of light by particles (i.e. Read More

Int J Audiol 2022 Apr 19:1-6. Epub 2022 Apr 19.

Department of Otolaryngology, University of Health Sciences Derince Research and Training Hospital, Kocaeli, Turkey.

Objective: The quantitative suppression rate of positional nystagmus (PN) by ocular fixation (OF) is unknown. This study aims to analyse the effect of OF on the slow phase velocity (SPV) of PN during diagnostic positional manoeuvres (DPMs) with videonystagmography in patients with benign paroxysmal positional vertigo (BPPV).

Design: DPMs were performed on 58 patients with BPPV, 33 (56. Read More

J Int Adv Otol 2022 Mar;18(2):188-191

Department of Audiology and Neurotology, Lyon University Hospital, Lyon, France; Paris Hearing Institute, Research Center of Institut Pasteur, Inserm U1120, Paris, France; Claude Bernard Lyon 1 University, Lyon, France.

A 73-year-old female was referred to our department for persistent left anterior benign paroxysmal positional vertigo refractory to multiple repositioning procedures and training physiotherapist exercises. The audiovestibular assessment and high resonance computed tomography of the petrosal bone confirmed the presence of a 5.4 mm large paucisymptomatic left anterior semicircular canal dehiscence. Read More

J Int Adv Otol 2022 Mar;18(2):177-182

Department of Otorhinolaryngology, San Gerardo Hospital, Monza, Italy; Department of Otorhinolaryngology, University of Milano-Bicocca Faculty of Medicine and Surgery, Monza, Italy.

Benign paroxysmal positional vertigo is a rare vestibular disorder in the pediatric population. It is a vestibulopathy characterized by brief attacks of vertigo, which occur after specific movements. This review aims to provide the current evidence regarding benign paroxysmal positional vertigo in children. Read More

J Int Adv Otol 2022 Mar;18(2):158-166

Department of Neuroscience, Psychology, Drug's Area and Child's Health, University of Florence, Italy.

Background: The aim of this study is to verify if (1) there is a link between hypovitaminosis D and benign paroxysmal positional vertigo, (2) the number of benign paroxysmal positional vertigo relapses decreases after vitamin D supplementation; and (3) benign paroxysmal positional vertigo response to physical therapy improves after hypovitaminosis D correction.

Methods: We enrolled 26 patients with benign paroxysmal positional vertigo and 24 subjects, who never suffered from vertigo, as a control group. All benign paroxysmal positional vertigo patients underwent physical therapy, once a week, until benign paroxysmal positional vertigo resolution. Read More

J Neurol Neurosurg Psychiatry 2022 Apr 11. Epub 2022 Apr 11.

Centre for Vestibular Neurology, Department of Brain Sciences, Imperial College, London, UK

Endocr Pract 2022 Apr 6. Epub 2022 Apr 6.

Department of Neurology, the Second Affiliated Hospital of Jiaxing University, Zhejiang, China. Electronic address:

Background: A high incidence of benign paroxysmal positional vertigo (BPPV) is reported in postmenopausal women, and the association between estradiol (E2) deficiency and the occurrence of BPPV was investigated.

Methods: Postmenopausal women with and without BPPV were included from 2016 to 2019, and 1-year follow-up was performed. Serum otolin-1 and E2 levels were assayed before the canalith repositioning treatment. Read More

Acta Otorrinolaringol Esp (Engl Ed) 2022 Mar-Apr;73(2):69-76

Servicio de Otorrinolaringología, Hospital de Cabueñes, Gijón, Asturias, Spain.

Background And Objective: Benign paroxysmal positional vertigo (BPPV) is the most common vertigo of labyrinthine origin, its social and healthcare impact is remarkable. It has recently been shown that single session treatment is as safe and effective as weekly treatment, which could have impact on direct and indirect costs related to the disease. The objective of this study is to determine whether single session treatment of unilateral posterior canal BPPV canalolithiasis is more efficient than conventional treatment. Read More

Auris Nasus Larynx 2022 Apr 3. Epub 2022 Apr 3.

Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Benign paroxysmal positional vertigo (BPPV) is characterized by positional vertigo (brief attacks of rotatory vertigo triggered by head position changes in the direction of gravity) and is the most common peripheral cause of vertigo. There are two types of BPPV pathophysiology: canalolithiasis and cupulolithiasis. In canalolithiasis, otoconial debris is detached from the otolithic membrane and floats freely within the endolymph of the canal. Read More

Med Pr 2022 Apr 6;73(2):143-150. Epub 2022 Apr 6.

Instytut Medycyny Pracy im. Jerzego Nofera / Nofer Institute of Occupational Medicine, Łódź, Poland (Klinika Audiologii i Foniatrii / Audiology and Phonistrics Clinic).

Background: The posturography test allows assessment of the entire function of balance system and quantitative, device-based verification of the clinical Romberg test. Therefore, the aim of this study is assessment of usefulness of posturography as primary test for balance disorders in occupational medicine.

Material And Methods: The study is cross-sectional, analyzing anonymous results of 1030 patients reporting dizziness and balance disorders. Read More

Biol Res 2022 Apr 4;55(1):16. Epub 2022 Apr 4.

Department of Otolaryngology, The Second Affiliated Hospital of Air Force Medical University, No. 1 Xinsi Road, Xi'an , 710038, China.

Background: Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV). Otolin, a secreted glycoprotein with a C-terminal globular domain homologous to the immune complement C1q, has been identified as a biomarker for BPPV. However, the role of complement C1q/TNF-related proteins (CTRPs) with a C-terminal globular domain in BPPV is unclear, so we explored the change of CTRPs in betahistine treated BPPV. Read More

OTO Open 2022 Jan-Mar;6(1):2473974X221089847. Epub 2022 Mar 29.

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Benign paroxysmal positional vertigo of the horizontal semicircular canal may present a differential diagnostic challenge. In addition to the classical positional nystagmus, a persistent nystagmus in a seated position occasionally occurs, so-called pseudo-spontaneous nystagmus (PSN), which can be mistaken for a central or peripheral spontaneous nystagmus. We report a case with cupulolithiasis of the horizontal semicircular canal presenting with horizontal PSN in a sitting position, with implications for a new pathomechanism of PSN. Read More

Front Neurol 2022 14;13:841677. Epub 2022 Mar 14.

Department of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.

Background: Otolin-1 is an inner ear-specific protein that is exclusively expressed in otoconia and vestibule and cochlea cells. Recent investigations reported that otolin-1 can cross the blood-labyrinthine barrier and that the levels in serum well-reflected otolith status. Serum otolin-1 levels in patients with benign paroxysmal positional vertigo (BPPV) are significantly elevated compared with healthy controls. Read More

Otolaryngol Head Neck Surg 2022 Mar 29:1945998221087664. Epub 2022 Mar 29.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.

Objective: To offer pragmatic, evidence-informed guidance on the use of systemic corticosteroids (SCS) for common otolaryngologic disorders.

Data Sources: PubMed, Cochrane Library, and American Academy of Otolaryngology-Head and Neck Surgery Foundation clinical practice guidelines.

Review Methods: A comprehensive search of published literature through November 2021 was conducted on the efficacy of SCS, alone or in combination with other treatments, for managing disorders in otolaryngology and the subdisciplines. Read More

Ann Indian Acad Neurol 2022 Jan-Feb;25(1):148-151. Epub 2021 Oct 11.

Department of Internal Medicine, Daswani Dental College, Kota, Rajasthan, India.

Clin Neurol Neurosurg 2022 04 8;215:107201. Epub 2022 Mar 8.

University of Health Sciences Izmir Tepecik Education and Research Hospital Department of Neurology, Izmir 35110, Turkey. Electronic address:

Objective: To evaluate demographic and clinical features of vestibular migraine (VM) patients METHODS: Four hundred fifteen patients with VM were evaluated by using a structured questionnaire in addition to clinical examination.

Results: The mean age of headache and vertigo onset was 25 years and 39 years, respectively. In 12. Read More

Otol Neurotol 2022 04;43(4):e482-e488

Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg.

Objective: The aim of this article is to evaluate older women who report dizziness on a daily or weekly basis, but not seeking medical care for their problems, for levels of patient-reported outcome measures related to dizziness, balance confidence, vestibular impairment, benign paroxysmal positional vertigo walking speed, Timed Up and Go (TUG), balance confidence, depression, and anxiety.

Study Design: Cross-sectional survey.

Setting: Secondary referral center. Read More

J Sci Med Sport 2022 Feb 15. Epub 2022 Feb 15.

School of Health Science and Social Work, Griffith University, Australia; Menzies Health Institute Queensland, Griffith University, Nathan Campus, Australia. Electronic address:

Objectives: To investigate for differences in vestibulo-ocular function between active male combat sport athletes and a healthy control group. In addition, to explore the relationship between symptom-based outcome measures with vestibulo-ocular function.

Design: Cross-sectional. Read More

Cureus 2022 Feb 27;14(2):e22647. Epub 2022 Feb 27.

Physical Medicine and Rehabilitation, Metropolitan Hospital Center, New York, USA.

Good treatments are available for many cases of vertigo due to a peripheral cause such as benign paroxysmal positional vertigo. Conversely, vertigo secondary to a central lesion remains a treatment challenge typically without good pharmacologic or other treatments. We have successfully treated two patients, the first to our knowledge, with central vertigo, one from brain injury, one after stroke, with low dose olanzapine which we found to quickly and dramatically resolve vertigo and permit functional normalization. Read More

Iran J Otorhinolaryngol 2021 Nov;33(119):339-346

 Department of Otorhinolaryngology Head and Neck surgery , Anadolu Medical Center, Kocaeli 41400, Turkey.

Introduction: Benign paroxysmal positional vertigo (BPPV) is a common cause of peripheral vestibular disturbances. Particle repositioning or liberatory maneuvers provide relief of symptoms in the majority of patients. However, studies mainly focus on success. Read More

Cureus 2022 Jan 20;14(1):e21460. Epub 2022 Jan 20.

Otolaryngology - Head and Neck Surgery, University of California San Francisco, San Francisco, USA.

Introduction While the mechanism of posterior canal benign paroxysmal positional vertigo (BPPV) is widely accepted as canalolithiasis, the pathophysiology of horizontal canal BPPV remains controversial. We seek to analyze vestibular test results of patients with horizontal canal BPPV with ageotropic nystagmus (AHC) and geotropic nystagmus (GHC) in comparison to patients with posterior canal BPPV (PC) to better understand its pathophysiology. Methods In a retrospective chart review of adults with BPPV at a tertiary referral balance center, we reviewed the clinical characteristics and compared videonystagmography, caloric, rotary chair, subjective visual vertical (SVV)/ subjective visual horizontal (SVH), and vestibular evoked myogenic potential (VEMP) results between groups. Read More