29,019 results match your criteria Benign Neoplasm of the Small Intestine

Life-threatening haematochezia in a man with two gastrointestinal stromal tumours.

BMJ Case Rep 2021 Jun 9;14(6). Epub 2021 Jun 9.

Internal Medicine, United Arab Emirates University, Al Ain, UAE

A man in his 30s was brought by ambulance to the emergency department with a complaint of frank bright red rectal bleeding and dizziness. His blood pressure was 60/18 mm Hg. He was resuscitated with intravenous normal saline and an emergency blood transfusion. Read More

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Neuroendocrine tumour of the ampulla of Vater: A rare neoplasm at an atypical site.

J Pak Med Assoc 2021 May;71(5):1486-1488

Department of General Surgery Unit-1, Lahore General Hospital, Lahore, Pakistan.

The periampullary neuroendocrine tumour is an infrequently occurring tumour. Its prevalence among gastrointestinal neuroendocrine neoplasms is less than 0.3%, and less than 2% out of periampullary tumours. Read More

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Small intestine duplication cyst with recurrent hematochezia: a case report and literature review.

BMC Gastroenterol 2021 Jun 1;21(1):246. Epub 2021 Jun 1.

Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Background: Small intestine duplication cysts (SIDCs) are rare congenital anatomical abnormalities of the digestive tract and a rare cause of hematochezia.

Case Presentation: We describe an adult female presented with recurrent hematochezia. The routine gastric endoscope and colonic endoscope showed no positive findings. Read More

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An Unusual Case of Meckel Diverticulitis Misdiagnosed as an Infected Urachal Cyst.

Medicina (Kaunas) 2021 May 13;57(5). Epub 2021 May 13.

Clinical Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University, 800216 Galați, Romania.

Meckel's diverticulum (MD), a remnant of the omphaloenteric duct, is among the most frequent intestinal malformations. Another embryonic vestige is the urachus, which obliterates, becoming the median umbilical ligament; the failure of this process can lead to a urachal cyst formation. We present a case of Meckel diverticulitis misdiagnosed as an infected urachal cyst. Read More

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Second Primary Tumors in Patients with Gastrointestinal Stromal Tumors: A Single-Center Experience.

Medicina (Kaunas) 2021 May 13;57(5). Epub 2021 May 13.

Department of Biostatistics and Medical Informatics, Süleyman Demirel University Faculty of Medicine, Isparta 32260, Turkey.

: In this study, we investigated the frequency and type of second primary malignant tumors (SPMTs) accompanying gastrointestinal stromal tumors (GISTs), patient and tumor characteristics, and follow-up and survival data. : We included 20 patients with SPMTs from a total of 103 patients with GISTs in a single center in Turkey. At the time of GIST diagnosis, patient age, sex, presentation symptoms, localization, pathological features of the tumor, stage, recurrence risk scoring for localized disease, treatments received, time of SPMT association, follow-up times, and survival analysis were recorded for each patient. Read More

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Peripheral T-Cell Lymphoma Possibly Due to Unrecognized Celiac Disease in an Elderly Patient: A Case Report.

Medicina (Kaunas) 2021 May 11;57(5). Epub 2021 May 11.

Department of Internal Diseases, Metabolic Disorders and Hypertension, Poznań University of Medical Sciences, Szamarzewskiego 84, 60-569 Poznań, Poland.

Celiac disease (CD) is widely perceived as a childhood disorder. However, it has been demonstrated that 19-34% of new CD cases are diagnosed in patients over 60 years of age and lack the typical presentation. A 76-year-old female was admitted to the clinic due to a recurrent fever that had lasted over a year accompanied by progressive weakness, weight loss of about 10 kg, dehydration, and malnutrition. Read More

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Splenocystojejunostomy for the treatment of a symptomatic splenic pseudocyst.

Ann R Coll Surg Engl 2021 Jun;103(6):e202-e205

Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.

Pancreatic pseudocyst is a widely recognised local complication following acute pancreatitis. Typically occurring more than four weeks after acute pancreatitis, a pseudocyst is a mature, encapsulated collection found within the peripancreatic tissues manifesting as abdominal pain, structural compression, gastroparesis, sepsis and organ dysfunction. Therapeutic interventions include endoscopic transpapillary or transmural drainage, percutaneous catheter drainage and open surgery. Read More

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Diagnostic and therapeutic challenge of unclassifiable enteropathies with increased intraepithelial CD103 CD8 T lymphocytes: a single center case series.

Scand J Gastroenterol 2021 May 31:1-10. Epub 2021 May 31.

University of Freiburg, Freiburg, Germany.

Objectives: Chronic diarrhea, villous atrophy and/or increased intraepithelial T-lymphocytes (IEL) occur in many inflammatory disorders including celiac disease (CD). However, a definite diagnosis is difficult to make in some patients despite an extensive diagnostic work-up. Clinical outcomes and histological phenotypes of such patients we refer to as unclassifiable enteropathy (UEP) remain unclear. Read More

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Lymphangiomatosis associated with protein losing enteropathy: A case report.

World J Clin Cases 2021 May;9(15):3758-3764

Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China.

Background: Lymphangiomatosis is a multisystem disorder that is rarely localized to the gastrointestinal tract. Lymphangiomatosis usually has no specific clinical presentation and is easily misdiagnosed. A case report and review of the literature on lymphangiomatosis associated with protein-losing enteropathy will help to improve the overall understanding of this disease. Read More

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A 61-year-old woman with jejunal lymphatic malformation visualized on computed tomography: a case report.

J Med Case Rep 2021 May 27;15(1):302. Epub 2021 May 27.

Department of Obstetrics and Gynecology, University of California Irvine, 333 City Boulevard West, Suite 1400, Orange, CA, 92868, USA.

Background: Jejunal lymphatic malformations are congenital lesions that are seldom diagnosed in adults and rarely seen on imaging.

Case Presentation: A 61-year-old Caucasian woman was initially diagnosed and treated for mucinous ovarian carcinoma. After an exploratory laparotomy with left salpingo-oophorectomy, a computed tomography scan of the abdomen and pelvis demonstrated suspicious fluid-containing lesions involving a segment of jejunum and adjacent mesentery. Read More

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Research progress on gut microbiota in patients with gastric cancer, esophageal cancer, and small intestine cancer.

Appl Microbiol Biotechnol 2021 Jun 26;105(11):4415-4425. Epub 2021 May 26.

School of Laboratory Medicine, Hangzhou Medical College, Zhejiang, 310053, Hangzhou, China.

The pathogenesis of gut microbiota in humans can be indicated due to the wide application of techniques, such as 16S rRNA sequencing. Presently, several studies have found a significant difference in fecal flora between normal individuals and patients with gastric cancer. Although clinical research on the feedback mechanism of gastric flora and gut microbiota is lacking, clarifying the relationship between gut microbiota and the characteristics of cancer is significant for the early diagnosis of gastric cancer. Read More

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Unusual case of amyloidosis presenting as a jejunal mass.

BMJ Case Rep 2021 May 25;14(5). Epub 2021 May 25.

Gastroenterology and Hepatology, Regions Hospital, Saint Paul, Minnesota, USA.

Amyloidosis constitutes a heterogeneous group of disorders of protein misfolding that can involve different organ systems. The disease can occur either in a systemic or localised manner that is well known to involve the gastrointestinal (GI) tract. GI amyloidosis can present with a wide range of symptoms including diarrhoea, bleeding and obstruction. Read More

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How to Manage Small Intestine (Jejunal and Ileal) Neuroendocrine Neoplasms Presenting with Liver Metastases?

Curr Oncol Rep 2021 May 20;23(7):85. Epub 2021 May 20.

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, A-1090, Vienna, Austria.

Purpose Of Review: Small intestinal neuroendocrine neoplasms (siNENs) are slowly growing tumours with a low malignant potential. However, more than half of the patients present with distant metastases (stage IV) and nearly all with locoregional lymph node (LN) metastases at the time of surgery. The value of locoregional treatment is discussed controversially. Read More

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Paraneoplastic pemphigus associated with post-transplant lymphoproliferative disorder after small bowel transplantation.

Pediatr Transplant 2021 May 20:e14023. Epub 2021 May 20.

Department of Pediatric Gastroenterology, University Medical Center Groningen, Groningen, The Netherlands.

Background: PNP is a malignancy-associated autoimmune mucocutaneous syndrome due to autoantibodies against plakins, desmogleins, and other components of the epidermis and basement membrane of epithelial tissues. PNP-causing malignancies comprise mainly lymphoproliferative and hematologic neoplasms. PNP is extremely rare, especially in children. Read More

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Immunohistochemical staining for IMP3 in patients with duodenal papilla tumors: assessment of the potential for diagnosing endoscopic resectability and predicting prognosis.

BMC Gastroenterol 2021 May 18;21(1):224. Epub 2021 May 18.

Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, 4668550, Japan.

Background: Endoscopic papillectomy of duodenal papillary tumors (PT) is indicated for adenomas or well-differentiated adenocarcinomas that do not involve the sphincter of Oddi. However, there is currently no reliable pre-operative method to diagnose the infiltration in the sphincter of Oddi.' Insulin-like growth factor 2 mRNA protein 3 (IMP3) staining is reportedly associated with advanced disease stage and clinical outcomes in many carcinomas. Read More

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Metastatic Hepatic Epitheloid Hemangioendothelioma in a Young Male: A Rare Presentation.

Gastrointest Tumors 2021 Apr 18;8(2):58-62. Epub 2021 Feb 18.

Department of General Surgery, AIIMS, Bhopal, Madhya Pradesh, India.

Hepatic EHE (epithelioid hemangioendothelioma) is an uncommon entity of vascular origin and a low-grade malignant tumor. Primary hepatic EHE is rare. These tumors can be multifocal at presentation like in the soft tissues, bones, brain, liver, and small intestine. Read More

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Common Presentation of an Uncommon Small Intestinal Lymphoma: A Rare Case Entity.

Gastrointest Tumors 2021 Apr 17;8(2):47-51. Epub 2021 Feb 17.

Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, India.

Primary gastrointestinal NHL accounts for 30-40% of all extranodal NHL. Primary gastrointestinal lymphomas constitute 5% of total gut neoplasms. Bowel perforation is a severe life-threatening complication and sometimes initial presentation of gastrointestinal lymphoma. Read More

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[Composite diffuse large B-cell lymphoma and CD20-positive peripheral T-cell lymphoma involving the small intestine: a case report].

Zhonghua Xue Ye Xue Za Zhi 2021 04;42(4):346

Department of Hematology, Affiliated Hospital of Nantong University, Nantong 226001, China.

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Prenatal diagnosis of megaduodenum using ultrasound: a case report.

BMC Pregnancy Childbirth 2021 May 11;21(1):370. Epub 2021 May 11.

Department of Ultrasound, Shengjing Hospital of China Medical University, No.36 Sanhao St, Shenyang, 110004, Liaoning, China.

Background: Congenital megaduodenum is a rare disorder; however, its prenatal diagnosis has not been reported previously. We report the case of an abdominal cystic mass in a fetus that was later diagnosed as megaduodenum.

Case Presentation: An abdominal cystic mass was found during ultrasonography of a fetus at 11 weeks of gestation. Read More

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[Pyogenic granuloma in small intestine associated with Cowden's disease in a patient with gastrointestinal bleeding:a case report].

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(5):462-472

Department of Internal Medicine II, Shimane University.

A 57-year-old female with a history of Cowden's disease was referred to our hospital because of black stool, loss of consciousness, and severe anemia. Upper and lower gastrointestinal endoscopy findings could not confirm the source of hemorrhage. Capsule endoscopy (CE) of the small intestine showed an active exudative hemorrhagic site near the ileum, although a definitive diagnosis was difficult. Read More

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Rare case of a duodenal de novo dedifferentiated gastrointestinal stromal tumour.

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Department of Medical Oncology, HealthCare Global Enterprises Ltd, Bangalore, Karnataka, India.

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Dedifferentiation in these tumours occurs rarely, and when it does occurs most commonly after prolonged treatment with imatinib. We report the case of a 64-year-old man who presented with a mass of 8×7×3 cm dimensions involving the duodenum and head of the pancreas. Read More

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Inflammatory myofibroblastic tumours of the duodenopancreaticobiliary tract.

BMJ Case Rep 2021 May 6;14(5). Epub 2021 May 6.

Department of Hepato Pancreato Biliary(HPB) Surgery and Liver Transplant, HealthCare Global Enterprises Ltd, Bangalore, Karnataka, India.

Inflammatory myofibroblastic tumours (IMTs) are rare benign neoplasms of intermediate malignant potential that are found in the lungs and rarely at extrapulmonary sites common in children and young adults. IMTs tend to be locally invasive and have some amount of metastatic potential as well. We present two cases of IMTs involving the duodenum, pancreas and distal bile duct. Read More

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Gastric adenocarcinoma at stage IV with complete remission after neoadjuvant therapy concurrent with adenosquamous carcinoma of the ampulla of Vater: a case report and literature review.

BMC Surg 2021 Apr 30;21(1):224. Epub 2021 Apr 30.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.

Background: Adenosquamous carcinoma (ASC) of the ampulla of Vater (AmV) is exceedingly rare with more aggressive behavior and worse prognosis than adenocarcinoma. The finding of ASC at the AmV in combination to the gastric adenocarcinoma has never been reported in the literature before.

Case Presentation: An old lady was diagnosed as gastric adenocarcinoma at stage IV with enlargement of supraclavicular lymph nodes by gastroscopy and histopathological evaluation 3 years ago. Read More

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Effectiveness of Intraoperative Indocyanine Green Fluorescence-Navigated Surgery for Superior Mesenteric Vein Thrombosis that Developed During Treatment for Intravascular Lymphoma: A Case Report.

Am J Case Rep 2021 Apr 30;22:e929549. Epub 2021 Apr 30.

Department of Surgery, Sunagawa City Medical Center, Sunagawa, Hokkaido, Japan.

BACKGROUND Superior mesenteric vein thrombosis (SMVT) is a relatively rare form of acute abdominal disease; less than 0.1% of laparotomy surgeries are performed for SMVT. In the presence of severe intestinal ischemia or necrosis caused by SMVT, immediate surgical intervention is required. Read More

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SARS-CoV-2 Viral Entry Proteins in Hyperandrogenemic Female Mice: Implications for Women with PCOS and COVID-19.

Int J Mol Sci 2021 Apr 25;22(9). Epub 2021 Apr 25.

Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

SARS-CoV-2, the causative agent of COVID-19, infects host cells using the angiotensin I converting enzyme 2 (ACE2) as its receptor after priming by host proteases, including TMPRSS2. COVID-19 affects multiple organ systems, and male patients suffer increased severity and mortality. Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in reproductive-age women and is characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. Read More

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Small Bowel Epithelial Precursor Lesions: A Focus on Molecular Alterations.

Int J Mol Sci 2021 Apr 22;22(9). Epub 2021 Apr 22.

Department of Internal Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, 27100 Pavia, Lombardy, Italy.

The wider use of gastrointestinal endoscopic procedures has led to an increased detection of small intestinal preneoplastic and neoplastic epithelial lesions, most of which are identified in the duodenum and ampullary region. Like their malignant counterparts, small intestinal glandular precursor lesions, which include adenomas and hamartomas, may arise sporadically or be associated with hereditary tumor syndromes, such as familial adenomatous polyposis, -associated polyposis, Lynch syndrome, Peutz-Jeghers syndrome, juvenile polyposis syndrome, and Cowden syndrome. In addition, dysplastic, preinvasive lesions have been observed adjacent to small bowel adenocarcinomas complicating immune-related disorders, such as celiac or Crohn's disease. Read More

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Arq Gastroenterol 2021 Jan-Mar;58(1):26-31

Universidade Federal de São Paulo, Disciplina de Gastroenterologia, São Paulo, SP, Brasil.

Background: Worldwide, colorectal cancer (CRC) and gastric cancer (GC) are the third and the fifth most prevalent, respectively. Diarrhea is a common symptom in patients on chemotherapy or radiotherapy treatment and can reduce treatment tolerance. Surgical resections and chemotherapy change the intestinal microbiota that can lead to lactose intolerance, small intestinal bacterial overgrowth (SIBO). Read More

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Author commentary on Mariko Sekiya et al.


Endoscopy 2021 05 22;53(5):v23. Epub 2021 Apr 22.

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CT Texture Analysis for Preoperative Identification of Lymphoma from Other Types of Primary Small Bowel Malignancies.

Biomed Res Int 2021 2;2021:5519144. Epub 2021 Apr 2.

Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Objectives: To explore the application of computed tomography (CT) texture analysis in differentiating lymphomas from other malignancies of the small bowel.

Methods: Arterial and venous CT images of 87 patients with small bowel malignancies were retrospectively analyzed. The subjective radiological features were evaluated by the two radiologists with a consensus agreement. Read More

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Updated Review on the Role of Curcumin in Gastrointestinal Cancers.

Adv Exp Med Biol 2021 ;1308:55-89

Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Malignant conditions of the gastrointestinal tract and accessory organs of digestion, including the oral cavity, esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus, are referred to as gastrointestinal cancers. Curcumin is a natural compound derived from turmeric with a wide range of biological activities. Several in vitro and in vivo studies have investigated the effects of curcumin on gastrointestinal cancers. Read More

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