654 results match your criteria Benign Lesions of the Ovaries


Factors Associated With Ovarian Preservation in Children and Adolescents With Primary Tumors of Ovary.

Indian Pediatr 2020 Jun;57(6):515-518

University of Split, School of Medicine, Soltanska 2, 21 000 Split, Croatia and Department of Pathology, University Hospital of Split, Spinciceva 1, 21 000 Split, Croatia.

Objective: To determine management of pediatric ovarian masses and identify the factors associated with ovarian preservation.

Methods: From January, 2002 to January, 2019 the case records of 72 patients (median age 14 y), who underwent surgery for ovarian tumors were retrospectively reviewed.

Results: Tumors were most common in the age group 14-17 yrs (58. Read More

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Evaluation of the usefulness of laparoscopy in the diagnosis and treatment of adnexal pathologies in the pediatric population.

Wideochir Inne Tech Maloinwazyjne 2020 Jun 28;15(2):366-376. Epub 2020 Mar 28.

Department of Children's Developmental Defects Surgery and Traumatology, Medical University of Silesia in Katowice, Zabrze, Poland.

Introduction: The current trend in adnexal surgery in children is to minimize the invasiveness of diagnostic and therapeutic procedures, reduce the number of complications and reduce the risk of infertility.

Aim: Evaluation of the usefulness and effectiveness of laparoscopy in diagnostics and treatment of pathological lesions of adnexa in the pediatric population and evaluation of the correlation of imaging with the intraoperative diagnosis during laparoscopy.

Material And Methods: The study included 89 patients aged 0-18 years (mean: 12. Read More

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http://dx.doi.org/10.5114/wiitm.2020.93998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233164PMC

Expression, Epigenetic, and Genetic Changes of HNF1B in Colorectal Lesions: an Analysis of 145 Cases.

Pathol Oncol Res 2020 Jun 1. Epub 2020 Jun 1.

Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studnickova 2, 12800, Prague 2, Czech Republic.

Hepatocyte nuclear factor 1 beta (HNF1B) is transcription factor which plays a crucial role in the regulation of the development of several organs, but also seems to be implicated in the development of certain tumours, especially the subset of clear cell carcinomas of the ovary and kidney. Depending on the type of the tumour, HNF1B may act as either a tumour suppressor or an oncogene, although the exact mechanism by which HNF1B participates in the process of cancerogenesis is unknown. Using immunohistochemical approach and methylation and mutation analysis, we have investigated the expression, epigenetic, and genetic changes of HNF1B on 40 cases of colorectal adenomas and 105 cases of colorectal carcinomas. Read More

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http://dx.doi.org/10.1007/s12253-020-00830-2DOI Listing

Primary ovarian leiomyoma: Imaging in a rare entity.

Radiol Case Rep 2020 Jul 20;15(7):1066-1070. Epub 2020 May 20.

Consultant Radiologist, Head of Department, Nanavati super-speciality Hospital, Mumbai, India.

Primary ovarian leiomyoma is a very rare benign mesenchymal tumor arising from the smooth muscle of walls of ovarian blood vessels. It is usually seen between 20 65 years of age. Being asymptomatic in many patients, these are incidentally detected. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.04.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243055PMC

A sporadic gastric-type endocervical adenocarcinoma with endometrial involvement and bilateral ovarian metastasis, a case report.

Gynecol Oncol Rep 2020 May 18;32:100572. Epub 2020 Apr 18.

Department of Gynecologic Oncology, MCC, United States.

•Gastric type endocervical adenocarcinoma (GAS) is rare in the United States.•GAS is an aggressive tumor and can metastasize unusual sites including peritoneal surfaces and adnexa.•Metastatic lesions can mimic benign/borderline mucinous tumors of ovaries. Read More

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http://dx.doi.org/10.1016/j.gore.2020.100572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182719PMC

Ovarian solid tumors: MR imaging features with radiologic-pathologic correlation.

Jpn J Radiol 2020 Apr 27. Epub 2020 Apr 27.

Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago, Tottori, 683-8504, Japan.

Ovarian solid tumors have variable histological types including benign and malignant tumors. In addition, non-neoplastic lesions sometimes show a tumor-like appearance. It is important to differentiate benign from malignant tumors. Read More

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http://dx.doi.org/10.1007/s11604-020-00976-8DOI Listing

[A rare case of cystadenoma in the small intestine].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Apr;52(2):382-384

Department of Oncology, Hebei Hosptical of Traditional Chinese Medicine Affiliated to Hebei University of Traditional Chinese Medicine, Shijiazhuang 050011, China.

In recent years, there have been more and more reports about cystadenoma. Cystadenoma can occur in many parts of the body, and cystadenoma in different parts may show different clinical symptoms, however, some patients with cystadenoma have no symptoms. The vast majority of cystadenomas are benign lesions, but a small number of cystadenomas can be malignant. Read More

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Robotic resection of a large ovarian leiomyoma.

Minerva Chir 2020 Apr;75(2):121-124

Division of General, Minimally Invasive and Robotic Surgery, University of Illinois at Chicago, Chicago, IL, USA.

Uterine leiomyomata are the most frequent leiomyomata. However, this benign tumor can also arise in unusual locations (e.g. Read More

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http://dx.doi.org/10.23736/S0026-4733.20.08253-XDOI Listing

Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Tourniquet as a Resource for Hepatic Transplant in Patient With Hepatic Adenomatosis: A Case Report.

Transplant Proc 2020 Mar 6;52(2):594-595. Epub 2020 Feb 6.

General and Digestive Surgery, Virgen de la Arrixaca Clinic and University Hospital, El Palmar, Murcia, Spain.

Background: Hepatic adenomatosis is defined as the presence of more than 10 adenomatous lesions seated on a healthy liver. The most frequent complication is bleeding, presenting a risk of malignant neoplasms of less than 10%.

Clinical Case: We present a case of a 28-year-old woman with polycystic ovary syndrome treated with oral contraceptives for 10 years. Read More

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http://dx.doi.org/10.1016/j.transproceed.2019.11.036DOI Listing

A rare case of trichilemmal ovarian carcinoma. Case report and review of the literature.

G Chir 2019 Jul-Aug;40(4):334-337

Trichilemmal ovarian carcinoma is very rare. A 52-years-old woman was admitted to University Hospital Department suffering from pain in the left iliaca fossa lasting for three months. Uterus was normal in size, painless as well as right adnexum. Read More

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[Borderline Ovarian Tumours: CNGOF Guidelines for Clinical Practice - Imaging].

Gynecol Obstet Fertil Senol 2020 03 28;48(3):260-276. Epub 2020 Jan 28.

Service de radiologie, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; ISCD, équipe médecine, Sorbonne université, université Paris 06, IUC, 75005 Paris, France. Electronic address:

Objective: To determine the place of imaging and the performance of different imaging techniques (transvaginal ultrasound with or without Doppler, scoring, CT, MRI) to differentiate benign tumour, borderline ovarian tumour (BOT) and malignant ovarian tumor. Differentiate the histological subtypes of BOT (serous, sero-mucinous, mucinous) and prediction in imaging of the possibility of conservative treatment.

Methods: The research was carried out over the last 16 years using the terms "MeSH" based on the query of the Medline® database and supplemented by the review of references contained in the meta-analyzes, systematic reviews and original articles included. Read More

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http://dx.doi.org/10.1016/j.gofs.2020.01.014DOI Listing

Clear Cell Papillary Cystadenoma of the Ovary Masquerading as Metastatic Clear Cell Renal Cell Carcinoma: A Case Report and Review of the Literature.

Int J Gynecol Pathol 2020 Jan 23. Epub 2020 Jan 23.

Department of Pathology, University of Chicago Medical Center, Chicago, Illinois (A.E.S., F.S.H., P.P., J.A.B., R.R.L.) Department of Pathology, Cooper University Hospital, Camden, New Jersey (J.E.B.).

Clear cell papillary cystadenoma of the epididymis is an uncommon benign neoplasm, usually seen in patients with von Hippel-Lindau disease. Morphologic and immunohistochemical examination aid in distinguishing clear cell papillary cystadenoma from malignant histologic mimics including low-grade mesothelial proliferations and metastatic clear cell renal cell carcinomas. Analogous lesions have been described in the female genital tract, often posing diagnostic challenges due to their low incidence. Read More

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http://dx.doi.org/10.1097/PGP.0000000000000666DOI Listing
January 2020

Genitourinary manifestations of endometriosis with emphasis on the urinary tract.

Abdom Radiol (NY) 2020 06;45(6):1711-1722

Department of Radiology, Mayo Clinic Arizona, Scottsdale, AZ, USA.

Endometriosis is a common benign condition affecting women. The disease has a broad spectrum of presentations from incidental lesions in asymptomatic women to causing significant and debilitating morbidity in others. Ectopic endometrial glands are located in predictable locations throughout the pelvis, including implantation on the ovaries and in the rectouterine cul-de-sac. Read More

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http://dx.doi.org/10.1007/s00261-019-02383-8DOI Listing

Highly differentiated follicular carcinoma of ovary: Use of imprint cytology at intraoperative consultation.

Diagn Cytopathol 2020 Apr 2;48(4):360-363. Epub 2019 Dec 2.

Department of pathology, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania.

Highly differentiated follicular carcinoma of ovary (HDFCO) is a rare entity known to arise in struma ovarii. Clinical presentation and radiological features mimic other cystic ovarian neoplasm. Thus, intraoperative diagnosis of this entity can be challenging. Read More

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http://dx.doi.org/10.1002/dc.24360DOI Listing

Adnexal incidentalomas on multidetector CT: how to manage and characterise.

J Obstet Gynaecol 2019 Dec 2:1-8. Epub 2019 Dec 2.

Department of Clinical Radiology, Medical School, University of Ioannina, Ioannina, Greece.

Although CT is not considered the examination of choice for the detection and characterisation of adnexal diseases, adnexal masses may be incidentally detected during CT examination performed for other clinical indications. Most adnexal incidentalomas are benign, and therefore may not require further investigation, follow-up or intervention; however, few of them may prove malignant. Multidetector CT has improved the diagnostic performance of the technique in the detection and differentiation of adnexal mass lesions. Read More

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http://dx.doi.org/10.1080/01443615.2019.1676214DOI Listing
December 2019

Hyperreactio luteinalis mimicking malignancy during pregnancy with elevated CA-125.

Taiwan J Obstet Gynecol 2019 Nov;58(6):885-887

Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, Taiwan; Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taiwan. Electronic address:

Objective: To report a case with benign bilateral ovarian tumor during pregnancy mimicking malignancy.

Case Report: A 32-year-old women at 20 weeks gestation with large bilateral adnexal masses found on prenatal ultrasound. The cysts had been growing gradually over the course of the pregnancy. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.07.033DOI Listing
November 2019

Ruptured primary mucinous cystadenoma of spleen leading to mucinous ascites.

BMJ Case Rep 2019 Nov 21;12(11). Epub 2019 Nov 21.

General Surgery, Indira Gandhi Medical College, Shimla, India

Mucinous cystadenoma are rare benign mucin-producing tumours. Primary mucinous neoplasms most commonly involve ovary, pancreas or appendix. They may rupture to produce mucous ascites/pseudomyxoma peritonei. Read More

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http://dx.doi.org/10.1136/bcr-2019-231212DOI Listing
November 2019

The Abnormal Ovary: Evolving Concepts in Diagnosis and Management.

Obstet Gynecol Clin North Am 2019 Dec 25;46(4):607-624. Epub 2019 Sep 25.

Department of Medical Imaging, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.

Ovarian lesions are common and require a consistent approach to diagnosis and management for best patient outcomes. In the past 20 years, there has been an evolution in the approach to abnormal ovarian lesions, with increasing emphasis on reducing surgery for benign disease, standardizing terminology, assessing risk of malignancy through use of evidence-based scoring systems, and triaging suspicious abnormalities to dedicated oncology centers. This article provides an evidence-based review of how these changes in diagnosis and management of ultrasound-detected abnormal ovarian lesions have occurred. Read More

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http://dx.doi.org/10.1016/j.ogc.2019.07.002DOI Listing
December 2019

Ovarian tumors: a survey of selected advances of note during the life of this journal.

Authors:
Robert H Young

Hum Pathol 2020 01 22;95:169-206. Epub 2019 Oct 22.

The James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

The author reviews highlights of advances in knowledge concerning ovarian tumor pathology since the time of an essay in the first issue of this Journal written by Dr Robert E. Scully, who, both before and for several decades after the Journal was instituted, made many original contributions to the field and was the major architect of the 1973 World Health Organization classification of ovarian tumors which was much more clear and logical than prior ones. The current review considers the neoplasms in essentially the same order as was done in the first issue of this journal and presents a personal look at the highlights of new information concerning various well-known categories, surface epithelial, germ cell, sex cord-stromal, metastatic neoplasms and briefly, benign so-called tumor-like lesions. Read More

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http://dx.doi.org/10.1016/j.humpath.2019.09.002DOI Listing
January 2020
2 Reads

Metachronous Second Primary Malignancies in Known Breast Cancer Patients on 18F-Fluoro-2-Deoxyglucose Positron Emission Tomography-Computerized Tomography in a Tertiary Care Center.

Indian J Nucl Med 2019 Oct-Dec;34(4):284-289

Department of Nuclear Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Introduction: Breast cancer is the most common malignancy among women all over the world, which accounts to 25% of all cancers. In known cases of breast cancer, the risk of developing another denovo malignancy is more when compared to low risk groups, which might be due to common environmental risk factors, treatment induced risk factors, Genetic susceptibility for mutations, presence of cancer syndromes or better detection due to close surveillance.

Objective: To study the profile of Metachronous 2 primary malignancies suspected on 18F-FDG PET CT in known Breast cancer patients. Read More

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http://dx.doi.org/10.4103/ijnm.IJNM_78_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771210PMC
October 2019
2 Reads

Expression of SMAD4 is Retained in Most Gynecologic Tumors with Mucinous Differentiation.

Int J Gynecol Pathol 2019 Sep 27. Epub 2019 Sep 27.

University of Miami/Jackson Health System, Jackson Memorial Hospital (S.A., K.A.) Miller School of Medicine, University of Miami (A.P.) Miami, Florida.

SMAD4 is a tumor suppressor gene that plays a role in cancer initiation and progression. A few studies have explored the value of immunohistochemistry for SMAD4 in gynecologic neoplasms, mainly in the ovary. However, literature is sparse when it comes to other sites such as endometrium and cervix, as well as in benign and borderline ovarian mucinous neoplasms. Read More

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http://dx.doi.org/10.1097/PGP.0000000000000637DOI Listing
September 2019
3 Reads

Uterus-like mass in the right broad ligament: A case report.

Medicine (Baltimore) 2019 Sep;98(38):e17246

Department of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong, PR China.

Rationale: Uterus-like masses (ULMs) are rare benign lesions that resemble the uterus.

Patient Concerns: Here, we describe the case of a woman with a ULM in the right broad ligament. A 51-year-old woman with a 2-month history of irregular vaginal bleeding was found to have a mass in the right broad ligament. Read More

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http://dx.doi.org/10.1097/MD.0000000000017246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756688PMC
September 2019
2 Reads
5.723 Impact Factor

Can preoperative findings help to interpret neoplastic and non-neoplastic lesions of ovary and affect surgical decisions in children and adolescents?

Arch Argent Pediatr 2019 10;117(5):294-400

Gaziantep University Faculty Of Medicine Department Of Pediatric Surgery, Gaziantep, Turkey.

Background: Ovarian masses are common in all pediatric age groups. Ovarian-sparing surgery is favored since most cases are benign or functional cysts. Detection of a few malignant cases prevents morbidity and mortality. Read More

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http://dx.doi.org/10.5546/aap.2019.eng.294DOI Listing
October 2019
1 Read

Amide proton transfer imaging for differentiating benign ovarian cystic lesions: Potential of first time right.

Eur J Radiol 2019 Nov 7;120:108656. Epub 2019 Sep 7.

Departments of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Purpose: To investigate whether amide proton transfer (APT) imaging is useful to differentiate benign ovarian cystic lesions.

Materials And Methods: This prospective study enrolled a total of 19 lesions in 18 patients with benign ovarian cystic lesion: serous cystadenoma (SCA), n = 4; mucinous cystadenoma (MCA), n = 9; or functional cyst (FC), n = 6. APT imaging was performed with three different presaturation pulse durations: 0. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.108656DOI Listing
November 2019
3 Reads

Role of a novel circulatory RNA-based biomarker panel expression in ovarian cancer.

IUBMB Life 2019 12 13;71(12):2031-2047. Epub 2019 Sep 13.

Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Ovarian cancer (OC) is considered the sixth commonest cancer affecting women globally. We choose novel integrated specific ovarian cancer RNA biomarker panel; pellino E3 ubiquitin protein ligase family member 3 (PELI3) gene expressions along with its selected epigenetic regulators (microRNA (miR-361-3p) and long noncoding RNA (lncRNA RP5-837J1.2) by bioinformatic methods. Read More

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http://dx.doi.org/10.1002/iub.2153DOI Listing
December 2019
1 Read
3.143 Impact Factor

Surgically treated ovarian lesions in preadolescent girls.

Acta Obstet Gynecol Scand 2020 01 6;99(1):105-111. Epub 2019 Sep 6.

Department of Pediatric Surgery, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland.

Introduction: The purpose of this study was to investigate the epidemiology and characteristics of surgically treated ovarian lesions in preadolescent girls.

Material And Methods: This was a retrospective cohort study including all 0- to 11-year-old girls operated at a single center from 1999 to 2016 for ovarian cysts, neoplasms or torsions. Patient charts were reviewed for symptoms, preoperative radiological imaging, operative details and histopathology. Read More

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http://dx.doi.org/10.1111/aogs.13717DOI Listing
January 2020
2 Reads

Tumors of the reproductive tract of sheep and goats: A review of the current literature and a report of vaginal fibroma in an Awassi ewe.

Vet World 2019 Jun 11;12(6):778-782. Epub 2019 Jun 11.

Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.

Aims: This study aimed to provide a summary of all online available literature of published clinical and histopathological data regarding tumors affecting the reproductive tract of female sheep and goats. In addition, a detailed description of the clinical history, clinical findings, and gross and histopathological findings of one case of vaginal fibroma in an adult Awassi sheep is provided for the first time.

Materials And Methods: Internet search engines such as PubMed, ResearchGate, Scopus, ScienceDirect, and Google Scholar were used to collect all published articles in refereed journals from 2000 to 2018 regarding tumors and tumor-like lesions involving the reproductive tract of ewes and does. Read More

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http://dx.doi.org/10.14202/vetworld.2019.778-782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661476PMC
June 2019
6 Reads

Immunohistochemical expression of CD44v9 and 8-OHdG in ovarian endometrioma and the benign endometriotic lesions adjacent to clear cell carcinoma.

J Obstet Gynaecol Res 2019 Nov 14;45(11):2260-2266. Epub 2019 Aug 14.

Department of Obstetrics and Gynecology, Nara Medical University, Nara, Japan.

Aim: Expression of CD44 variant isoforms (CD44v) promotes the synthesis of reduced glutathione and contributes to reactive oxygen species defense through up-regulation of the intracellular antioxidant. The aim of the study was to investigate the expression of CD44v9 and oxidative DNA damage marker, 8-OHdG, in benign ovarian endometrioma (OE) and OE harboring clear cell carcinomas (CCC).

Methods: A retrospective study was performed at the Department of Gynecology, Nara Medical University hospital from January 2006 to December 2012. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jog.14093
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http://dx.doi.org/10.1111/jog.14093DOI Listing
November 2019
2 Reads

Novel diagnosis of mesenteric endometrioma: Case report.

Medicine (Baltimore) 2019 Jul;98(29):e16432

Department of Obstetrics Gynecology, Carol Davila University of Medicine and Pharmacy.

Rationale: Mesenteric cysts are benign gastrointestinal cystic lesions, with an incidence of <1/100 000. They usually develop in the small bowel mesentery, mesocolon (24%), retroperitoneum (14.5%), and very rarely originate from the sigmoid mesentery. Read More

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http://dx.doi.org/10.1097/MD.0000000000016432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709129PMC
July 2019
4 Reads

It Is Necessary to Purpose an Add-on to the American Classification of Endometriosis? This Disease Can Be Compared to a Malignant Proliferation While Remaining Benign in Most Cases. EndoGram® Is a New Profile Witness of Its Evolutionary Potential.

Front Surg 2019 7;6:27. Epub 2019 Jun 7.

Department of Gynecology and Obstetrics, HFR, Fribourg Cantonal Hospital, Friborg, Switzerland.

Endometriosis is a curious pathology that has been the topic of many international publications. Its etiology remains mysterious but seems to have multiple causes. It is a complex disease whose lesions are very heterogeneous in where they can occur (deep endometriosis, superficial, ovarian cyst), extent, associated symptoms, evolution or aggressiveness of the disease, and response to treatments. Read More

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http://dx.doi.org/10.3389/fsurg.2019.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566301PMC
June 2019
15 Reads

Factors Associated With Management of Pediatric Ovarian Neoplasms.

Pediatrics 2019 07 4;144(1). Epub 2019 Jun 4.

Division of Pediatric Surgery, Department of Surgery and the Research Institute and

Background: Available evidence supports ovary-sparing surgery for benign ovarian neoplasms; however, preoperative risk stratification of pediatric ovarian masses can be difficult. Our objective of this study was to characterize the surgical management of pediatric ovarian neoplasms across 10 children's hospitals and to identify factors that could potentially aid in the preoperative risk stratification of these lesions.

Methods: A retrospective review of girls and women aged 2 to 21 years who underwent surgery for an ovarian neoplasm between 2010 and 2016 at 10 children's hospitals was performed. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-2537DOI Listing
July 2019
27 Reads

Performance of IOTA ADNEX model in evaluating adnexal masses in a gynecological oncology center in China.

Ultrasound Obstet Gynecol 2019 Dec 11;54(6):815-822. Epub 2019 Nov 11.

Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China.

Objective: To evaluate the diagnostic accuracy of the International Ovarian Tumor Analysis (IOTA) Assessment of Different NEoplasias in the adneXa (ADNEX) model in the preoperative diagnosis of adnexal masses using data from a gynecological oncology center in China.

Methods: This was a single-center, retrospective diagnostic accuracy study based on ultrasound data collected prospectively, between May and December 2017, from 278 patients with at least one adnexal (ovarian, paraovarian or tubal) mass. Clinical and pathologic information, serum CA 125 level and ultrasonographic findings were collected. Read More

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http://dx.doi.org/10.1002/uog.20363DOI Listing
December 2019
8 Reads

Classification of human ovarian cancer using functional, spectral, and imaging features obtained from in vivo photoacoustic imaging.

Biomed Opt Express 2019 May 8;10(5):2303-2317. Epub 2019 Apr 8.

Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.

We report in this pilot study the diagnostic results of in vivo imaging of patients with ovarian lesions, using a co-registered photoacoustic and ultrasound (PAT/US) system. A total of 39 ovaries from 24 patients were imaged in vivo. PAT functional features, i. Read More

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http://dx.doi.org/10.1364/BOE.10.002303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524604PMC
May 2019
7 Reads

Mucinous cystadenocarcinoma in the renal pelvis: primary or secondary? Case report and literature review.

Acta Chir Belg 2019 Sep 9:1-8. Epub 2019 Sep 9.

Department of Radiology, AZ Sint-Blasius , Dendermonde , Belgium.

: Cystic lesions in the renal pelvis may cause a diagnostic dilemma. These lesions may be benign or (pre)malignant and primary of secondary. : A 65-year-old woman presents with a complex cystic mass in the lower pole of the left kidney measuring approximately 16 cm in size and classified as Bosniak type 2F with minimally thickened septa and thick calcifications on non-contrast-enhanced computed tomography. Read More

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http://dx.doi.org/10.1080/00015458.2019.1617515DOI Listing
September 2019
8 Reads

Benign ovarian lesions with restricted diffusion.

Radiol Bras 2019 Mar-Apr;52(2):106-111

Instituto Português de Oncologia de Lisboa Francisco Gentil - Radiologia, Lisboa, Portugal.

Developments in magnetic resonance imaging have expanded its role in the assessment of the female pelvis, including the diagnosis of ovarian lesions. In this setting, diffusion-weighted imaging has proven its diagnostic value, which is particularly important in differentiating between benign and malignant ovarian tumors. In general, the latter show restricted diffusion, whereas the former do not. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
Publisher Site
http://dx.doi.org/10.1590/0100-3984.2018.0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472866PMC
April 2019
110 Reads

Analysis of Prophylactic Salpingo-oophorectomy at the Time of Hysterectomy for Benign Lesions.

J Midlife Health 2019 Jan-Mar;10(1):29-32

Department of Obstetrics and Gynecology, NKP Salve Institute of Medical Sciences and Research Centre, Nagpur, Maharashtra, India.

Background: Prophylactic salpingo-oophorectomy refers to the removal of clinically normal ovaries at the time of hysterectomy for benign lesions, to reduce the risk of ovarian and breast cancer in future. This risk reduction holds true for high-risk women, i.e. Read More

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http://dx.doi.org/10.4103/jmh.JMH_70_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459073PMC
April 2019
3 Reads

High prevalence of benign mammary tumors in a rat model of polycystic ovary syndrome during postmenopausal period.

Gynecol Endocrinol 2019 Aug 16;35(8):679-684. Epub 2019 Apr 16.

a Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in reproductive-age women. Significant associations between PCOS and benign breast diseases (BBD) and a possibly potential association between PCOS and breast cancer have been reported. The etiology of these events of mammary glands in PCOS remains unclear. Read More

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http://dx.doi.org/10.1080/09513590.2019.1576613DOI Listing
August 2019
8 Reads

Spectrum of magnetic resonance imaging findings in ovarian torsion.

Pol J Radiol 2018 18;83:e588-e599. Epub 2018 Dec 18.

Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Purpose: Ovarian torsion is the twisting of the ovary on its vascular pedicle resulting in vascular compromise. Diagnosis of ovarian torsion is challenging in patients who have atypical clinical or ultrasound (US) findings. The objective of our study was to demonstrate the magnetic resonance imaging (MRI) features of ovarian torsion to help radiologists make a conclusive diagnosis when the clinical and US findings are unclear. Read More

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http://dx.doi.org/10.5114/pjr.2018.81157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384404PMC
December 2018
9 Reads

Diagnostic accuracy of CA125 and HE4 in ovarian carcinoma patients and the effect of confounders on their serum levels.

Curr Probl Cancer 2019 10 16;43(5):450-460. Epub 2019 Jan 16.

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Zagazig City, Al Sharqia Governorate, Egypt.

Objectives: To evaluate the diagnostic accuracy of serum cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) in the prediction of malignant ovarian masses then to analyze the effect of personal criteria and medical diseases on this accuracy.

Study Design: This prospective study was performed in Zagazig University Hospital. The eligibility criteria for inclusion were; consecutive women, at any age ≥18 years, with established diagnosis of ovarian mass based on symptoms, signs, and imaging techniques. Read More

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http://dx.doi.org/10.1016/j.currproblcancer.2018.12.004DOI Listing
October 2019
7 Reads

[Sex cord-stromal tumors of the ovary : Current aspects with a focus on granulosa cell tumors, Sertoli-Leydig cell tumors, and gynandroblastomas].

Authors:
F Kommoss H-A Lehr

Pathologe 2019 Feb;40(1):61-72

Institut für Pathologie, Medizin Campus Bodensee, Röntgenstr. 2, 88048, Friedrichshafen, Deutschland.

Sex cord-stromal tumors of the ovary (SCSTO) comprise a heterogeneous and fascinating group of neoplasms with diverse clinicopathological features, including benign lesions as well as tumors with malignant potential. Clinically, SCSTO may be associated with hyperestrogenic or androgenic function as a result of steroid hormone production by the tumor cells.Histological diagnosis may be challenging due to complex and sometimes overlapping morphological features of the various tumor types. Read More

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http://dx.doi.org/10.1007/s00292-018-0562-3DOI Listing
February 2019
14 Reads

High-grade serous ovarian carcinoma with mucinous differentiation: report of a rare and unique case suggesting transition from the "SET" feature of high-grade serous carcinoma to the "STEM" feature.

Diagn Pathol 2019 Jan 12;14(1). Epub 2019 Jan 12.

Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, 501-1194, Japan.

Background: High-grade serous carcinoma, a representative high-grade ovarian carcinoma, is believed to be closely associated with a TP53 mutation. Recently, this category of ovarian carcinoma has gained increasing attention owing to the recognition of morphological varieties of TP53-mutated high-grade ovarian carcinoma. Herein, we report the case of a patient with high-grade serous carcinoma with mucinous differentiation. Read More

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https://diagnosticpathology.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13000-019-0781-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330567PMC
January 2019
30 Reads

Pitfalls of Frozen Section in Gynecological Pathology: A Case of Ovarian Serous Surface Papillary Adenofibroma Imitating Malignancy.

Int J Surg Pathol 2019 May 18;27(3):268-270. Epub 2018 Dec 18.

1 Rutgers-New Jersey Medical School, Newark, NJ, USA.

Serous cystadenofibromas are uncommon benign ovarian lesions, consisting of both fibrous and epithelial components, that are usually cystic but may contain solid or papillary architecture that can be confused with a malignancy on imaging. Papillary architecture seen on frozen section may also falsely steer the pathologist in the direction of a diagnosis of a borderline serous tumor. Overcalling the lesion may lead to more aggressive surgery than necessary, so extensive tissue sampling and consideration of this entity is important in possibly avoiding this mistake. Read More

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http://dx.doi.org/10.1177/1066896918818894DOI Listing
May 2019
5 Reads

Adnexal torsion in symptomatic women: a single-centre retrospective study of diagnosis and management.

J Obstet Gynaecol 2019 Apr 8;39(3):349-354. Epub 2018 Nov 8.

a Department of Gynaecology , Fernandez Hospital , Hyderabad , India.

This retrospective study aimed to evaluate the sonographic diagnosis and management strategy of symptomatic adnexal torsion at a teaching hospital in Hyderabad, India. All women with abdominal pain and preoperative or operative diagnosis of adnexal torsion from January 2011 to December 2015 were included. A total of 76 women with 78 episodes were included; 28 (36%) occurred during pregnancy. Read More

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https://www.tandfonline.com/doi/full/10.1080/01443615.2018.1
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http://dx.doi.org/10.1080/01443615.2018.1494702DOI Listing
April 2019
20 Reads

Torsion Ovary, an Unusual Presentation of Carcinoma Appendix Detected in Whole-Body F-18 2-Fluoro 2-deoxy Glucose Positron Emission Tomography/Computed Tomography Scan.

Indian J Nucl Med 2018 Oct-Dec;33(4):331-333

Department of Nuclear Medicine, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.

Torsion ovary is one of the common emergencies in gynecology requiring surgery. Torsion ovary is generally caused by cystic lesions of ovary and benign tumors. Malignant tumors rarely present as torsion ovary. Read More

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http://www.ijnm.in/text.asp?2018/33/4/331/242954
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http://dx.doi.org/10.4103/ijnm.IJNM_97_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194758PMC
November 2018
37 Reads

Role of perfusion CT in the evaluation of adnexal masses.

J Obstet Gynaecol 2019 Feb 27;39(2):218-223. Epub 2018 Sep 27.

c Department of Cytology and Gynecological Pathology , Post Graduate Institute of Medical Education and Research , Chandigarh , India.

The objective of this study was to evaluate the role of perfusion computed tomography (PCT) in differentiating benign from malignant adnexal masses. Twenty patients, each of pathologically proven malignant and benign adnexal masses who had undergone PCT on 64-slice CT scanner, were included in the study. The PCT parameters, viz. Read More

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https://www.tandfonline.com/doi/full/10.1080/01443615.2018.1
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http://dx.doi.org/10.1080/01443615.2018.1479382DOI Listing
February 2019
40 Reads

Multiple Synchronous Lesions in the Genital Tract of a Female: A Rare Combination with Unrelated Histogenesis.

J Menopausal Med 2018 Aug 31;24(2):133-137. Epub 2018 Aug 31.

Department of Pathology, MES Medical College, Perinthalmanna, Kerala, India.

Presenting a case of endometrioid adenocarcinoma of the endometrium, benign cystic teratoma of one ovary, fibrothecoma in the other ovary and adenomyosis in the uterus. Such a combination of synchronous lesion is very rare and is not reported in the English medical literature. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.6118/jmm.2018.24
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http://dx.doi.org/10.6118/jmm.2018.24.2.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127024PMC
August 2018
9 Reads

Clinicopathological Characteristics of Ovarian Metastasis from Colorectal and Pancreatobiliary Carcinomas Mimicking Primary Ovarian Mucinous Tumor.

Anticancer Res 2018 Sep;38(9):5465-5473

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

Background/aim: A subset of carcinomas metastatic to the ovary can exhibit growth patterns closely resembling ovarian mucinous cystadenoma and borderline tumor. They can be misinterpreted as underlying primary ovarian mucinous tumors and can be erroneously used to suggest that the carcinomatous component arises from mucinous precursor lesions.

Materials And Methods: We investigated the clinicopathological characteristics of 11 cases of metastatic carcinoma that had metastasized from colorectal and pancreatobiliary carcinoma and mimicked primary ovarian mucinous tumors. Read More

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http://dx.doi.org/10.21873/anticanres.12879DOI Listing
September 2018
13 Reads

Adnexal lesions: Imaging strategies for ultrasound and MR imaging.

Diagn Interv Imaging 2019 Oct 1;100(10):635-646. Epub 2018 Sep 1.

Departments of Radiology, hôpital Tenon, Sorbonne universités, UPMC université Paris 06, Institut universitaire de cancérologie, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75020 Paris, France.

Adnexal lesions are routinely encountered in general practice. Ultrasound is the first line of investigation in determining the benign or malignant potential of an adnexal lesion. In the cases of classic simple cysts, hemorrhagic cysts, endometriomas, dermoids and obviously malignant lesions, ultrasound may be sufficient for management recommendations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22115684183015
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http://dx.doi.org/10.1016/j.diii.2018.06.003DOI Listing
October 2019
8 Reads