3,875 results match your criteria Benign Gastric Tumors


Adenoma Malignum Diagnosed Postoperatively in a Case of Fibroid Uterus: Case Report with Review of Literature.

J Midlife Health 2018 Oct-Dec;9(4):219-221

Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

"Minimal deviation adenocarcinoma" of the uterine cervix (MDA), historically known as Adenoma Malignum, is a rare variant of cervical adenocarcinoma. Both the clinicians and pathologists must be vigilant about this entity as it could be mistaken for a benign pathology both clinically and microscopically, which can prove disastrous to the patient as these tumors behave like adenocarcinomas We hereby report an incidentally detected case of AM which was diagnosed in a post-menopausal female postoperatively. We discuss the intraoperative complications, histopathological diagnosis, post-operative management and follow up. Read More

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http://dx.doi.org/10.4103/jmh.JMH_102_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332719PMC
January 2019

Serum chromogranin A for the diagnosis of gastroenteropancreatic neuroendocrine neoplasms and its association with tumour expression.

Oncol Lett 2019 Feb 5;17(2):1497-1504. Epub 2018 Dec 5.

Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China.

The aim of the present study was to assess the clinical value of serum chromogranin A (CgA) levels in patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) and to compare them with tumour expression of CgA. A total of 109 consecutive patients with confirmed GEP-NENs were enrolled in this prospective study between December 2012 and August 2016, including 73 patients with primary or recurrent GEP-NENs and 36 patients with GEP-NENs that were treated following surgery. Furthermore, 30 patients with benign gastrointestinal diseases and 30 healthy volunteers served as control groups. Read More

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http://dx.doi.org/10.3892/ol.2018.9795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341841PMC
February 2019
1 Read

Giant Brunner's gland hamartoma causing retrograde jejuno-duodenal intussusception: A case report.

Ann Med Surg (Lond) 2019 Feb 4;38:37-41. Epub 2019 Jan 4.

Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia.

Brunner's gland hamartoma is a rare benign duodenal tumor. It occurs in Brunner's glands, which are found in the duodenum and produce secretions that protect the duodenum from pancreatic enzymes, gastric acid, and other agents. Endoscopic or surgical resection is required for these hamartomas. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327855PMC
February 2019
1 Read

Pediatric plexiform fibromyxoma: A PRISMA-compliant systematic literature review.

Medicine (Baltimore) 2019 Jan;98(3):e14186

Department of Pathology, National Hospital Organization Beppu Medical Center, 1473 Oaza-Uchikamado, Beppu, Oita, Japan.

Background: Plexiform fibromyxoma (PF) is a rare gastric mesenchymal tumor, with approximately 80 cases reported to date. Gastrointestinal stromal tumor, the most common primary mesenchymal tumor of the stomach, shows different biological and clinical characteristics between adult and pediatric patients.

Objectives: This systematic literature review was conducted to elucidate the pathological and clinical features of pediatric PF compared to adult PF. Read More

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http://dx.doi.org/10.1097/MD.0000000000014186DOI Listing
January 2019
1 Read

Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer.

Gut Liver 2018 Dec 19. Epub 2018 Dec 19.

Department of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.

Background/aims: Fundic gland polyps (FGPs), hyperplastic polyps (HPs) and xanthomas (XTs) are common benign gastric lesions that can be diagnosed by endoscopic appearance alone in most cases. The aim of this study was to evaluate associations between gastric cancer and these benign lesions.

Methods: Two expert endoscopists reviewed a series of gastroscopy images. Read More

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http://www.gutnliver.org/journal/view.html?doi=10.5009/gnl17
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http://dx.doi.org/10.5009/gnl17136DOI Listing
December 2018
5 Reads

Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.

Biomed Res Int 2018 25;2018:6124927. Epub 2018 Nov 25.

Centre for Osteonecrosis and Joint-Preserving & Reconstruction, Orthopaedic Department, China-Japan Friendship Hospital, Chaoyang District, Beijing, China.

Background: Previous literatures have investigated the change of miR-20a expression level in the progression of multiple cancers and its influence on patients' survival outcome, but results of now-available evidence are inconsistent.

Objective: To elucidate the prognostic value of circulating and tissue-based miR-20a for patients with various cancers.

Methods: A systematic search and review of eligible publications were carried out in three electronic databases including the Cochrane Library, PubMed, and Embase, and the methodological quality of included studies was assessed according to Newcastle-Ottawa Scale (NOS). Read More

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http://dx.doi.org/10.1155/2018/6124927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286746PMC
November 2018
6 Reads

Clinical Value of Positron Emission Tomography-Computed Tomography Combined with Ultrasound in Detection of Primary Tumors in Patients with Malignant Ascites.

Cancer Biother Radiopharm 2018 Dec 26. Epub 2018 Dec 26.

1 Department of Medical Ultrasound, The Affiliated Hospital of Chengdu Medical College , Chengdu, China .

Objective: To investigate and discuss the clinical value of positron emission tomography-computed tomography (PET-CT) combined with ultrasound in detection of primary tumors in patients with malignant ascites (MA).

Materials And Methods: A total of 122 malignant tumor patients with ascites as the initial symptom and 48 patients with benign ascites were enrolled in this study. All patients underwent PET-CT and abdominal B-ultrasound examinations. Read More

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http://dx.doi.org/10.1089/cbr.2018.2630DOI Listing
December 2018
2 Reads
1.381 Impact Factor

Plexiform fibromyxoma of the small bowel: A case report.

World J Clin Cases 2018 Dec;6(15):1067-1072

Department of Endoscopy, the Affiliated Hospital of Guizhou Medical University, Guiyang 550001, Guizhou Province, China.

Background: Plexiform fibromyxoma is a rare, special type of mesenchymal tumor. The most common presenting symptoms are anemia, hematemesis, and hematochezia, without sex or age predilection. The reported cases have mainly occurred in the gastric antrum and pylorus region, with some cases in the duodenum. Read More

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http://www.wjgnet.com/2307-8960/full/v6/i15/1067.htm
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http://dx.doi.org/10.12998/wjcc.v6.i15.1067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288503PMC
December 2018
10 Reads

Gastric schwannoma: report of two cases and review of the literature.

Int J Surg Case Rep 2018 3;53:495-499. Epub 2018 Nov 3.

1st Propaedeutic Surgery Department, AHEPA University Hospital of Thessaloniki, Greece.

Introduction: Gastrointestinal schwannomas are benign, slow-growing and usually asymptomatic tumors. In some cases bleeding, epigastric pain and palpable mass may be occurring. Preoperative diagnosis is challenging due to the difficulty of differentiation from other submucosal tumors. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279989PMC
November 2018
1 Read

A novel reconstructive strategy for pancreaticoduodenectomy following Roux-en-Y distal gastrectomy.

G Chir 2018 Nov-Dec;39(6):399-402

The rate of pancreaticoduodenectomy (PD) performed for both benign and malignant periampullary diseases has increased. In addition, Roux-en-Y reconstruction after distal gastrectomy for cancer or ulcer is still widely used. Therefore, a surgeon may be confronted with a partially- gastrectomized patient who needs a PD. Read More

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December 2018
6 Reads

Self-expanding metal stent procedure for afferent loop syndrome with ascending cholangitis caused by remnant gastric cancer: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13072

Department of Surgery, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju.

Rationale: Self-expanding metal stent placement is a useful procedure for intestinal obstruction. Afferent loop syndrome after gastrectomy is an uncommon complication of gastroenterostomy reconstruction. Ascending cholangitis caused by afferent loop syndrome is a potential, but rare, complication. Read More

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http://dx.doi.org/10.1097/MD.0000000000013072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320138PMC
December 2018
3 Reads

Apatinib inhibits tumor growth and angiogenesis in PNET models.

Endocr Connect 2019 Jan;8(1):8-19

Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, People's Republic of China.

Angiogenesis has a pivotal role in the growth and metastasis of pancreatic neuroendocrine tumors (PNETs). Apatinib inhibits angiogenesis as a highly selective KDR inhibitor and has been used to treat advanced gastric cancer and malignancies in clinical settings. However, the efficacy of apatinib in PNETs remains unclear. Read More

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http://dx.doi.org/10.1530/EC-18-0397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330719PMC
January 2019
14 Reads

The value of oral contrast ultrasonography in the diagnosis of gastric cancer in elderly patients.

World J Surg Oncol 2018 Dec 7;16(1):233. Epub 2018 Dec 7.

Department of Ultrasonography, Chongming branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 25 South Gate Road, Cheng Qiao Town, Chongming District, Shanghai, 202150, China.

Background: This study aims to investigate the value of oral contrast ultrasonography (OCUS) in the diagnosis of gastric cancer in elderly patients.

Methods: OCUS data obtained from patients ≥ 60 years old were retrospectively analyzed and compared with gastroscopy results.

Results: Among the 12,716 subjects examined by OCUS, 5021 subjects were ≥ 60 years old, which accounted for 39. Read More

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http://dx.doi.org/10.1186/s12957-018-1527-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286526PMC
December 2018
2 Reads

Pathologic analyses of peritoneal nodules in gastric cancer patients during surgery-A single cancer center experience with diagnostic pitfalls.

Pathol Res Pract 2019 Jan 15;215(1):195-199. Epub 2018 Nov 15.

Department of Pathology & Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81, Irwon-ro, Gangnam-Gu, Seoul, 06351, Republic of Korea. Electronic address:

Background: Gastric carcinoma (GC) is the second most common cause of cancer-related deaths worldwide. During operations, nodular lesions of the peritoneum are often sent for frozen section (FS). For pathologists, FS of the peritoneum is challenging due to sparse and discohesive tumor cells in a fibrotic background. Read More

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http://dx.doi.org/10.1016/j.prp.2018.11.013DOI Listing
January 2019
1 Read

Evaluating Clinical Genome Sequence Analysis by Watson for Genomics.

Front Med (Lausanne) 2018 9;5:305. Epub 2018 Nov 9.

Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.

Oncologists increasingly rely on clinical genome sequencing to pursue effective, molecularly targeted therapies. This study assesses the validity and utility of the artificial intelligence Watson for Genomics (WfG) for analyzing clinical sequencing results. This study identified patients with solid tumors who participated in in-house genome sequencing projects at a single cancer specialty hospital between April 2013 and October 2016. Read More

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https://www.frontiersin.org/article/10.3389/fmed.2018.00305/
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http://dx.doi.org/10.3389/fmed.2018.00305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237914PMC
November 2018
10 Reads

Solitary fibrous tumor of the stomach with high-grade sarcomatous dedifferentiation.

J Surg Case Rep 2018 Nov 19;2018(11):rjy307. Epub 2018 Nov 19.

Department of Surgery, Creighton University Medical Center, Omaha, NE, USA.

Solitary fibrous tumors (SFT) are uncommon fibroblastic mesenchymal neoplasms that display a wide range of histologic behaviors. These tumors, which are estimated to account for 2% of all soft tissue neoplasms, typically follow a benign clinical course. However, it is estimated that 10-30% of SFTs are malignant and demonstrate aggressive behavior with local recurrence and metastasis up to several years after surgical resection. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjy30
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http://dx.doi.org/10.1093/jscr/rjy307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240737PMC
November 2018
9 Reads

Clinicopathological characteristics and prognosis of primary appendiceal stromal tumors.

World J Surg Oncol 2018 Nov 16;16(1):225. Epub 2018 Nov 16.

Department of Gastric Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, No.44 Xiaoheyan Road, Dadong District, Shenyang, 110042, Liaoning Province, People's Republic of China.

Background: Gastrointestinal stromal tumors (GISTs) account for less than 1% of all gastrointestinal tumors. The biological behaviors of GISTs vary from benign to malignant. GISTs are common in the stomach (55. Read More

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https://wjso.biomedcentral.com/articles/10.1186/s12957-018-1
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http://dx.doi.org/10.1186/s12957-018-1524-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240235PMC
November 2018
12 Reads

Detection of gastric cancer and its histological type based on iodine concentration in spectral CT.

Cancer Imaging 2018 Nov 9;18(1):42. Epub 2018 Nov 9.

Department of Radiology, the First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou, 450052, Henan, China.

Background: Computed tomography (CT) imaging is the most common imaging modality for the diagnosis and staging of gastric cancer. The aim of this study is was to prospectively explore the ability of quantitative spectral CT parameters in the detection of gastric cancer and its histologic types.

Methods: A total of 87 gastric adenocarcinoma (43 poorly and 44 well-differentiated) patients and 36 patients with benign gastric wall lesions (25 inflammation and 11 normal), who underwent dual-phase enhanced spectral CT examination, were retrospectively enrolled in this study. Read More

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http://dx.doi.org/10.1186/s40644-018-0176-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230291PMC
November 2018
1 Read

Diagnostic challenges in differentiating intramural gastric abscess from gastric cancer: Two case reports.

Medicine (Baltimore) 2018 Oct;97(43):e12756

Department of Gastroenterology, Zhejiang Provincial People's Hospital.

Rationale: Intramural gastric abscess is a rare clinical condition. It is frequently neglected because of the absence of specific clinical symptoms and misdiagnosed due to the difficulty in differentiating a benign lesion from a malignant one on the gastric wall. Several imaging techniques are helpful for identifying an intramural gastric abscess. Read More

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http://dx.doi.org/10.1097/MD.0000000000012756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221696PMC
October 2018
32 Reads

Endoscopic Enucleation Is Effective and Relatively Safe in Small Gastric Subepithelial Tumors Originating from Muscularis Propria.

Dig Dis Sci 2019 Feb 3;64(2):524-531. Epub 2018 Nov 3.

Division of Gastroenterology, Department of Internal Medicine, Inha University College of Medicine, Inha University Hospital, 27, Inhang-ro, Jung-Gu, Incheon, 22332, Republic of Korea.

Background: Gastric subepithelial tumors originating from muscularis propria (MP) are usually benign, but some have malignant potential.

Aims: The aim of this study was to evaluate the utility of endoscopic enucleation for the diagnosis and treatment of MP tumors.

Patients And Methods: From January 2010 to February 2018, eighty patients with gastric MP tumors underwent endoscopic enucleation at our hospital. Read More

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http://link.springer.com/10.1007/s10620-018-5348-1
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http://dx.doi.org/10.1007/s10620-018-5348-1DOI Listing
February 2019
9 Reads

A Newborn with Gastric Hemangioma Treated Using Propranolol.

Pediatr Gastroenterol Hepatol Nutr 2018 Oct 10;21(4):341-346. Epub 2018 Oct 10.

Division of Neonatology, Department of Pediatrics, Turgut Ozal Medical Center, Inonu University School of Medicine, Malatya, Turkey.

Gastric hemangiomas are rare benign vascular tumors that can cause severe gastrointestinal system bleeding. We presented the case of a neonate with fresh bleeding and melena from the orogastric tube and detected gastric hemangioma in esophagogastroduodenoscopic examination. Propranolol is widely used in treatment of cutaneous hemangiomas and non-gastric gastrointestinal system hemangiomas. Read More

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http://dx.doi.org/10.5223/pghn.2018.21.4.341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182481PMC
October 2018
2 Reads

D1359Y mutation in a patient with gastric polyposis and cancer susceptibility: A case report and review of literature.

World J Gastroenterol 2018 Oct;24(38):4412-4418

Division of Hematology and Medical Oncology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei 10491, Taiwan.

Gastric polyposis is a rare disease. Not all polyps progress to cancer. Monoallelic mutation in Fanconi anemia (FA) genes, unlike biallelic gene mutations that causes typical FA phenotype, can increase risks of cancers in a sporadic manner. Read More

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http://dx.doi.org/10.3748/wjg.v24.i38.4412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189845PMC
October 2018
3 Reads

Clinical prediction of solitary pulmonary nodule after a curative resection for gastric cancer.

Jpn J Clin Oncol 2018 Dec;48(12):1083-1087

Division of Thoracic Surgery, National Cancer Center Hospital East, Chiba, Japan.

Background: Gastric cancer metastasis to the lung can rarely manifest as solitary pulmonary nodule. The surgical strategies are different between metastasis from gastric cancer and primary lung cancer; therefore, the clinical prediction of solitary pulmonary nodule is important.

Methods: Between September 2006 and September 2016, 38 patients with a history of curative resection for gastric cancer who subsequently underwent lung resection for solitary pulmonary nodule at our institution were evaluated. Read More

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https://academic.oup.com/jjco/advance-article/doi/10.1093/jj
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http://dx.doi.org/10.1093/jjco/hyy146DOI Listing
December 2018
10 Reads

Clinical Comparison of Spleen-Preserving Distal Pancreatectomy With or Without Splenic Vessel Preservation: A Systematic Review and Meta-analysis.

J Laparoendosc Adv Surg Tech A 2018 Oct 12. Epub 2018 Oct 12.

1 Department of General Surgery, Shanghai Tenth People's Hospital, Tongji University of Medicine , Shanghai, China .

Objectives: Spleen-preserving distal pancreatectomy with splenic vessel preservation (SVP) and only the save of short gastric and left gastroepiploic vessels called the Warshaw technique (WT) are the optimal procedures to resect benign or borderline malignant tumors of the left pancreas. The aim of this meta-analysis was to assess the intra- and postoperative outcomes between SVP and the WT.

Methods: We searched studies that compared the intra- and postoperative outcomes between SVP and the WT from PubMed, Embase, and the Cochrane Library (2004-2017). Read More

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http://dx.doi.org/10.1089/lap.2018.0135DOI Listing
October 2018
1 Read

Characterization of subepithelial lesions of the stomach and esophagus by contrast-enhanced EUS: A retrospective study.

Endosc Ultrasound 2018 Sep 26. Epub 2018 Sep 26.

Endoscopic Unit, Paoli Calmettes Institute, Marseille, France.

Background And Objectives: Subepithelial lesions (SELs) of the upper part of the digestive tract are rare, and it can be difficult to characterize them. Recently, contrast-enhanced endosonography (EUS) and elastometry have been reported as useful adjuncts to EUS and EUS-guided fine needle aspiration (EUS-FNA) in cases of pancreatic mass and lymph node involvement. The aim of this retrospective analysis was to evaluate whether contrast-enhanced EUS can discriminate benign submucosal lesions from malignant ones. Read More

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http://dx.doi.org/10.4103/eus.eus_89_17DOI Listing
September 2018
5 Reads

Giant symptomatic gastric lipoma: A case report and literature review.

Int J Surg Case Rep 2018 9;51:313-317. Epub 2018 Sep 9.

Division of Surgical Oncology, DeWitt Daughtry Family Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA; Sylvester Comprehensive Cancer Center, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA. Electronic address:

Introduction: Lipomas are uncommon tumors of the gastrointestinal tract; gastric lipomas account for <1% of all gastric tumors encountered (Nickloes and Sutphin [1]). Giant gastric lipomas, defined as ≥10 cm, are exceedingly rare with only 6 cases reported since 1980 (Cappell et al., Termos et al. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183036
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http://dx.doi.org/10.1016/j.ijscr.2018.08.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154433PMC
September 2018
13 Reads

Life-threatening giant esophageal neurofibroma with severe tracheal stenosis: a case report.

Surg Case Rep 2018 Sep 3;4(1):107. Epub 2018 Sep 3.

Department of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama, Kanagawa, 230-0012, Japan.

Background: Benign esophageal tumors are relatively rare, and a neurofibroma in the esophagus is extremely rare. Dysphagia is the most common clinical manifestation in patients with esophageal neurofibroma, and no cases of giant esophageal neurofibroma with severe tracheal stenosis have been reported.

Case Presentation: A 73-year-old woman presented with shortness of breath, and computed tomography scan exhibited a giant mediastinal tumor causing severe tracheal stenosis. Read More

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http://dx.doi.org/10.1186/s40792-018-0517-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120858PMC
September 2018
13 Reads

Prevalence and risk factors for upper gastrointestinal diseases in health check-up subjects: a nationwide multicenter study in Korea.

Scand J Gastroenterol 2018 Aug 31;53(8):910-916. Epub 2018 Aug 31.

j Department of Internal Medicine , Seoul National University Bundang Hospital , Seongnam , South Korea.

Objectives: The prevalence of upper gastrointestinal disease is expected to change following advances in socioeconomic status and improved hygiene in Korea. The aim of this study was to investigate the recent trends in upper gastrointestinal diseases based on endoscopic findings and Helicobacter pylori (H. pylori) seroprevalence in subjects undergoing health check-up at tertiary centers in Korea. Read More

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http://dx.doi.org/10.1080/00365521.2018.1487992DOI Listing
August 2018
13 Reads
2.330 Impact Factor

[Chinese Consensus on Endoscopic Diagnosis and Management of Gastrointestinal Submucosal Tumor(Version 2018)].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Aug;21(8):841-852

Surgical Section of Chinese Society of Digestive Endoscopology; Chinese Physicians Association Endoscope Branch Digestive Endoscopy Professional Committee; Gastrointestinal Surgery Section of Chinese Society of Surgery.

The Chinese Consensus on Endoscopic Diagnosis and Management of Gastrointestinal Submucosal Tumors is the first guideline in the area of gastrointestinal submucosal tumors(SMT) in China. SMTs of the Gastrointestinal tract are bulge lesions that originate from muscularis mucosa, submucosa, or muscularis propria. Endoscopic treatment of SMT is an effective way to improve the quality of life for patients, to reduce the burden on patients' families and the society, and to save national medical resources. Read More

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August 2018
3 Reads

[Option for different surgeries in treating small gastrointestinal stromal tumors].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Jul;43(7):767-771

Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, China.

Objective: To explore the differences in biological characteristics for the small gastrointestinal stromal tumors and the incidence of complications and recurrence between the traditional surgical treatment and endoscopic treatment.
 Methods: We collected the relevant clinical and pathological data from patients who were diagnosed as gastrointestinal stromal tumors with the diameter less than 2 cm by the Department of Pathology of Xiangya Hospital from January 2009 to December 2015. The complications and recurrence after the surgical treatment were analyzed. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.07.011DOI Listing
July 2018
12 Reads

Atypical anastomotic malignancies of small bowel after subtotal gastrectomy with Billorth II gastroenterostomy for peptic ulcer: Report of three cases and review of the literature.

World J Gastrointest Oncol 2018 Jul;10(7):194-201

Fourth Surgical Department, Medical School, Aristotle University of Thessaloniki, Thessaloniki 57010, Greece.

Aim: To present patients who developed small-bowel malignancy at the level of the gastrointestinal anastomosis decades after a subtotal gastrectomy for ulcer, to review relevant literature, and to attempt to interpret the reasons those cancers developed to these postsurgical non-gastric sights.

Methods: For the current retrospective study and review of literature, the surgical and histopathological records dated from January 1, 1993 to December 31, 2017 of our department were examined, searching for patients who have undergone surgical treatment of small-bowel malignancy to identify those who have undergone subtotal gastrectomy for benign peptic ulcer. A systematic literature search was also conducted using PubMed, EMBASE, and Cochrane Library to identify similar cases. Read More

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http://dx.doi.org/10.4251/wjgo.v10.i7.194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068855PMC
July 2018
3 Reads

Endoscopically Assisted Laparoscopic Gastric Resection for Benign and Malignant Lesions: A Report of Two Cases.

Am J Case Rep 2018 Jul 28;19:884-890. Epub 2018 Jul 28.

Digestive System Endoscopy Unit, Democritus University of Thrace, Alexandroupoli, Greece.

BACKGROUND The first gastric resection for stomach cancer was performed in 1879, and the first gastric resection for gastric ulcer disease was performed in 1882. During the 1990s, the first laparoscopic gastrostomies were reported. During the past decade, laparoscopic techniques have developed rapidly, gaining wide clinical acceptance. Read More

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http://dx.doi.org/10.12659/AJCR.909387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078009PMC
July 2018
2 Reads

Gastrointestinal schwannomas: a rare but important differential diagnosis of mesenchymal tumors of gastrointestinal tract.

BMC Surg 2018 Jul 25;18(1):47. Epub 2018 Jul 25.

Department of Surgery, University Hospital Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Germany.

Background: Schwannomas of gastrointestinal tract are rare, mostly benign and notably different neoplasms from conventional schwannomas that arise in soft tissue or the central nervous system. These tumors are of clinical importance since they should always be considered in the differential diagnosis of submucosal lesions of gastrointestinal tract.

Methods: Seven patients with a pathologically proven gastrointestinal schwannoma were identified in our series of mesenchymal tumors and reviewed retrospectively. Read More

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http://dx.doi.org/10.1186/s12893-018-0379-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060462PMC
July 2018
5 Reads

Safety and efficacy of a minimally invasive cell sampling device ('Cytosponge') in the diagnosis of esophageal pathology: a systematic review.

Eur J Gastroenterol Hepatol 2018 11;30(11):1261-1269

Department of Medicine.

Esophageal adenocarcinoma is an increasingly common cause of morbidity and mortality in developed countries. Most cases are considered the consequence of chronic gastroesophageal reflux disease, with subsequent Barrett's metaplasia and dysplasia. Because progression from Barrett's metaplasia to cancer occurs over many years, endoscopic screening and surveillance programs have been established, albeit with little or no consideration for cost-effectiveness. Read More

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http://dx.doi.org/10.1097/MEG.0000000000001210DOI Listing
November 2018
2 Reads

Self-expandable metallic stent application for the management of upper gastrointestinal tract disease.

Turk J Surg 2018 30;34(2):101-105. Epub 2018 Apr 30.

Department of General Surgery, Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey.

Objective: The aim of the present study was to share our experiences of the use of self-expandable metallic stent for the upper gastrointestinal tract disease.

Material And Methods: We retrospectively reviewed the medical records of 18 patients who underwent self-expandable metallic stent implantation procedure for anastomosis stricture, anastomosis leak, or spontaneous fistula of the upper gastrointestinal tract at two different surgery clinics. Self-expandable metallic stent implantation procedures were performed while keeping the patient under sedation and the correct stent localization was verified using fluoroscopy. Read More

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http://dx.doi.org/10.5152/turkjsurg.2017.3740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048644PMC
April 2018
4 Reads

Current clinical management of gastrointestinal stromal tumor.

World J Gastroenterol 2018 Jul;24(26):2806-2817

Department of Gastroenterology, Aso Iizuka Hospital, Iizuka 820-8505, Japan.

Gastrointestinal stromal tumors (GISTs) are the most common malignant subepithelial lesions (SELs) of the gastrointestinal tract. They originate from the interstitial cells of Cajal located within the muscle layer and are characterized by over-expression of the tyrosine kinase receptor KIT. Pathologically, diagnosis of a GIST relies on morphology and immunohistochemistry [KIT and/or discovered on gastrointestinal stromal tumor 1 (DOG1) is generally positive]. Read More

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http://dx.doi.org/10.3748/wjg.v24.i26.2806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048423PMC
July 2018
2 Reads

Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues.

Ann Surg Oncol 2018 Sep 12;25(9):2767-2775. Epub 2018 Jul 12.

Department of Surgery, Stony Brook University Hospital, New York, USA.

Background: Organoids are three-dimensional in vitro models of human disease developed from benign and malignant gastrointestinal tissues with tremendous potential for personalized medicine applications. We sought to determine whether gastric cancer patient-derived organoids (PDOs) could be safely established from endoscopic biopsies for rapid drug screening.

Methods: Patients underwent esophagogastroduodenoscopy (EGD) for surveillance or staging and had additional forceps biopsies taken for PDO creation. Read More

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http://dx.doi.org/10.1245/s10434-018-6662-8DOI Listing
September 2018
9 Reads

A Simple Method to Aid Safe Resection Margin During Sleeve Gastrectomy in Patients With Incidental Gastric Lesions.

Surg Laparosc Endosc Percutan Tech 2018 Dec;28(6):e106-e108

İstanbul Bariatrics, Obesity Center, İstanbul, Turkey.

In contrast to colonic tattooing, data on dye-marking before gastric operations are scarce. A simple method of gastric tattooing before sleeve gastrectomy (SG) is presented. SG, under tattoo guidance has never been reported. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000553DOI Listing
December 2018

Increased number of arginase 1-positive cells in the stroma of carcinomas compared to precursor lesions and nonneoplastic tissues.

Pathol Res Pract 2018 Aug 28;214(8):1179-1184. Epub 2018 Jun 28.

Department of Pathology, Dongguk University College of Medicine, Gyeongju, Republic of Korea.

Arginase 1 (Arg1) is involved in dampening the response of antitumor T lymphocytes. Arg1 expression has been reported in a variety of cancer cell lines and tumor-associated myeloid-derived cells. However, its examination in situ in tumor microenvironment is poorly investigated. Read More

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http://dx.doi.org/10.1016/j.prp.2018.06.016DOI Listing
August 2018
12 Reads

URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion.

Biomed Res Int 2018 31;2018:4060728. Epub 2018 May 31.

Department of Urology, Sun Yat-sen Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

Upregulated gene 11 (URG11), a new gene upregulated by hepatitis B virus X protein, is involved in the development and progression of several tumors, including liver, stomach, lung, and colon cancers. However, the role of URG11 in prostate cancer remains yet to be elucidated. By determined expression in human prostate cancer tissues, URG11 was found significantly upregulated and positively correlated with the severity of prostate cancer, compared with that in benign prostatic hyperplasia tissues. Read More

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http://dx.doi.org/10.1155/2018/4060728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000846PMC
January 2019
15 Reads

Invasive inflammatory fibroid polyp of the stomach: a case report and literature review.

BMC Gastroenterol 2018 May 31;18(1):74. Epub 2018 May 31.

Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan.

Background: Inflammatory fibroid polyps (IFPs) are rare mesenchymal lesions that affect the gastrointestinal tract. IFPs are generally considered benign, noninvasive lesions; however, we report a case of an invasive gastric IFP. To the best of our knowledge, this is only the second case report of an invasive gastric IFP. Read More

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http://dx.doi.org/10.1186/s12876-018-0808-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984322PMC
May 2018
3 Reads

Gastric Schwannoma: A Case Report and Review of the Literature for Gastric Submucosal Masses Distinction.

Case Rep Med 2018 10;2018:1230285. Epub 2018 Apr 10.

Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Schwannomas origin from Schwann cells sheath and generally are benign, slow-growing, and asymptomatic neoplasms which frequently appear in the head and neck. Although gastrointestinal schwannoma is really rare, the most affected organ in GI system is the stomach. Gastric schwannoma forms 0. Read More

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https://www.hindawi.com/journals/crim/2018/1230285/
Publisher Site
http://dx.doi.org/10.1155/2018/1230285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914132PMC
April 2018
8 Reads

Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia.

Clin Med Insights Gastroenterol 2018 18;11:1179552218778627. Epub 2018 May 18.

Department of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC, USA.

Background: Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients.

Aim: To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men. Read More

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http://dx.doi.org/10.1177/1179552218778627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960842PMC
May 2018
5 Reads

[Progress and controversy on diagnosis and treatment of gastric stump cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):588-592

Department of Gastrointestinal Surgery, Laboratory of Surgical Oncology, Peking University People's Hospital, Beijing 100044, China.

Gastric stump cancer (GSC) is a carcinoma arising from the remnant stomach following gastric surgery for benign or malignant disease, and is more common in men. The risk of morbidity has an obvious time dependence. GSC incidence is likely to rise with lengthening of the initial operation interval. Read More

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May 2018
3 Reads

[Risk factor analysis and prediction model establishment of lymph node metastasis in remnant gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):541-545

Department of Gastric Surgery, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

Objective: To explore the risk factors and establish an effective model to predict lymph node metastasis (LNM) for remnant gastric cancer (RGC).

Methods: Clinicopathological characteristics of 91 RGC patients undergoing radical gastrectomy at Sun Yat-sen University Cancer Center from January 2000 to December 2017 were retrospectively analyzed. RGC was defined as cancer detected in the remnant stomach >5 years for primary benign diseases or >10 years for malignant diseases following distal gastrectomy. Read More

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May 2018
3 Reads

[Clinicopathological characteristics and prognosis analysis of 217 patients with carcinoma in the remnant stomach].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):535-540

Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, Qingdao 266003, China.

Objective: To evaluate the clinicopathological features and prognostic factors of carcinoma in the remnant stomach (CRS).

Methods: Clinicopathological data of 217 consecutive CRS patients from January 2000 to March 2017 at Department of Gastrointestinal Surgery, The Affiliated Hospital of Qingdao University were retrospectively analyzed. CRS was defined as the primary cancer arising from the remnant stomach following gastrectomy, regardless of the initial disease or operation, and at no special time interval. Read More

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May 2018
9 Reads

[Clinicopathological characteristics and prognostic factor analysis of carcinoma in remnant stomach cancer at Peking University Cancer Hospital].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):522-528

Department of Gastrointestinal Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing 100142,China.

Objective: To investigate the interval time to canceration, clinicopathological characteristics and prognostic factors of carcinoma in remnant stomach (CRS) in patients with primary benign diseases or primary malignant tumors.

Methods: Based on the criteria of the definition of CRS proposed by Japanese Gastric Cancer Association in 2017, a retrospective analysis was conducted on clinicopathological characteristics of patients diagnosed with CRS at Peking University Cancer Hospital from March 1992 to March 2017. Between patients with primary benign diseases (CBS-B group) and primary malignant tumors (CBS-M group), continuous variables were compared using the Student's t-test or the Mann-Whitney U test; categorical variables were compared using the chi-square test or Fisher's exact test. Read More

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May 2018
3 Reads

[Pathological staging criteria for carcinoma in the remnant stomach: an exploratory study].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):514-521

Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing 100044, China.

Objective: To explore the prognostic value of the tumor-ratio-metastasis (TRM) staging system for carcinoma in the remnant stomach(CRS).

Methods: Clinicopathological data of 91 CRS patients who underwent surgery at Peking University People's Hospital between March 1992 and December 2017 were retrospectively analyzed. According to the ratio of metastatic lymph node to dissected lymph node, the R staging was obtained, and the pN staging was replaced by the R staging to create the TRM staging. Read More

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May 2018
1 Read

[Advertent problems about gastric stump cancer surgery].

Authors:
Han Liang

Zhonghua Wei Chang Wai Ke Za Zhi 2018 May;21(5):502-506

Department of Stomach Cancer, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.

Due to different disease background of gastric stump cancer(GSC) patients (benign or malignant lesion, reconstruction of digestive tract, etc.), the GSC surgical procedure and the difficulty of lymphadenectomy are also different. The extent of radical lymphadenectomy for gastric stump cancer should extend beyond D2 lymphadenectomy, according to the different backgrounds of initial disease, reconstructions, and tumor location. Read More

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May 2018
1 Read