3,990 results match your criteria Benign Gastric Tumors


Pancreaticoduodenectomy for the treatment of pancreatic neoplasms in children: A Pediatric Surgical Oncology Research Collaborative study.

Pediatr Blood Cancer 2020 Jul 13:e28425. Epub 2020 Jul 13.

Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.

Background: To better characterize short-term and long-term outcomes in children with pancreatic tumors treated with pancreaticoduodenectomy (PD).

Methods: Patients 21 years of age or younger who underwent PD at Pediatric Surgical Oncology Collaborative (PSORC) hospitals between 1990 and 2017 were identified. Demographic, clinical information, and outcomes (operative complications, long-term pancreatic function, recurrence, and survival) were collected. Read More

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http://dx.doi.org/10.1002/pbc.28425DOI Listing

Immunohistochemical analysis of beta-catenin, E-cadherin and p53 in canine gastrointestinal epithelial tumors.

J Vet Med Sci 2020 Jul 13. Epub 2020 Jul 13.

Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo.

Wnt/beta-catenin signaling, E-cadherin and p53 reportedly play important roles in the development and/or progression of human gastrointestinal cancer. The present study evaluated the roles of beta-catenin, E-cadherin and p53 in canine gastrointestinal tumors. Endoscopic biopsy or surgically resected samples, a total of 131, including 38 gastric, 13 small intestinal and 80 large intestinal tumors, were obtained from 95 dogs. Read More

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http://dx.doi.org/10.1292/jvms.20-0297DOI Listing

Endoscopic Management of Ganglioneuroma in the Stomach.

ACG Case Rep J 2020 May 6;7(5):e00382. Epub 2020 May 6.

Division of Gastroenterology and Hepatology, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH.

Ganglioneuromas are rare benign tumors of neuroblastic origin that can occur anywhere along the sympathetic chain. They are rarely found in the gastrointestinal tract and can appear as solitary polypoid lesions or diffuse as part of a familial syndrome. They are often asymptomatic but may present with nonspecific symptoms depending on their anatomic location. Read More

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http://dx.doi.org/10.14309/crj.0000000000000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289278PMC

Diagnosing Gastric Mesenchymal Tumors by Digital Endoscopic Ultrasonography Image Analysis.

Clin Endosc 2020 Jun 18. Epub 2020 Jun 18.

Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

Gastric mesenchymal tumors (GMTs) are incidentally discovered in national gastric screening programs in Korea. Endoscopic ultrasonography (EUS) is the most useful diagnostic modality for evaluating GMTs. The differentiation of gastrointestinal stromal tumors from benign mesenchymal tumors, such as schwannomas or leiomyomas, is important to ensure appropriate clinical management. Read More

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http://dx.doi.org/10.5946/ce.2020.061DOI Listing

More than Just a Hole in the Wall: Evolving Management and Treatment Paradigms of Suppurative Gastritis.

Dig Dis Sci 2020 Jun 12. Epub 2020 Jun 12.

Division of Gastroenterology & Hepatology, Medical College of Georgia, Digestive Health Center, Augusta University, 1120 15th St., Augusta, GA, 30912, USA.

Suppurative gastritis is an uncommon lesion and often an occult cause of upper abdominal pain without florid signs of a septic focus. There are two main phenotypic forms: (1) localized, also referred to as gastric abscess; and (2) diffuse, in which the differential diagnosis includes a more diverse range of benign and malignant lesions. Cross-section imaging such as CT allows for rapid diagnosis and demonstrates the location and extent, but not the specific etiology, of the lesion. Read More

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http://dx.doi.org/10.1007/s10620-020-06356-6DOI Listing

Gastric schwannoma.

Clin Case Rep 2020 May 21;8(5):925-926. Epub 2020 Feb 21.

UTHSC College of Medicine Memphis TN USA.

Gastric Schwannomas are rare benign slow-growing tumors and warrant treatment/resection only when symptomatic. Watchful waiting is recommended for incidental or asymptomatic schwannomas. Read More

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http://dx.doi.org/10.1002/ccr3.2747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250990PMC

Robotic-assisted versus open distal pancreatectomy for benign and low-grade malignant pancreatic tumors: a propensity score-matched study.

Surg Endosc 2020 May 26. Epub 2020 May 26.

Pancreatic Surgery Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Huangpu District, Shanghai, 200025, China.

Background: This study aimed to compare the short-term outcomes of open and robotic-assisted distal pancreatectomy (ODP and RDP) for benign and low-grade malignant tumors.

Methods: The patients who underwent RDP and ODP for benign or low-grade malignant pancreatic tumors at our center were included. After PSM at a 1:1 ratio, the perioperative variations in the two cohorts were compared. Read More

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http://dx.doi.org/10.1007/s00464-020-07639-9DOI Listing

Serous Microcystic Cystadenocarcinoma of the Pancreas with Synchronous Liver Metastases: Clinical Characteristics and Management.

Cureus 2020 Apr 17;12(4):e7707. Epub 2020 Apr 17.

2nd Department of Surgery, "Aretaeio" Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.

Serous cystadenocarcinoma of the pancreas is a rare but well-established entity. The origin and evolution of this disorder remain unclear, but even metastatic cases have an excellent prognosis. These tumors are very similar to benign serous cystic neoplasms (SCNs) of the pancreas, except that they tend to be larger, are locally invasive, and present distant metastasis. Read More

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http://dx.doi.org/10.7759/cureus.7707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233488PMC

The first malignant primary hepatic glomus tumor: A case report.

Int J Surg Case Rep 2020 11;70:197-200. Epub 2020 May 11.

Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

Introduction: Glomus tumors (GTs) are rare neoplasms that originate from the modified smooth muscle cells of glomus bodies and occasionally arise from visceral primary sites. All previously reported primary hepatic GTs were benign. Here we report the first malignant primary hepatic GT. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229426PMC

Which size is the best cutoff for primary small gastric gastrointestinal stromal tumor?

J Gastrointest Oncol 2020 Apr;11(2):402-410

Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510000, China.

Background: The biological behavior of primary small gastric gastrointestinal stromal tumor (gGIST) is indolent. The cutoff size categorizing small gGIST continues to be controversial. To date, there is no consensus regarding whether it should be 1 cm, 2 cm, or another size. Read More

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http://dx.doi.org/10.21037/jgo.2020.03.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212102PMC

A sporadic gastric-type endocervical adenocarcinoma with endometrial involvement and bilateral ovarian metastasis, a case report.

Gynecol Oncol Rep 2020 May 18;32:100572. Epub 2020 Apr 18.

Department of Gynecologic Oncology, MCC, United States.

•Gastric type endocervical adenocarcinoma (GAS) is rare in the United States.•GAS is an aggressive tumor and can metastasize unusual sites including peritoneal surfaces and adnexa.•Metastatic lesions can mimic benign/borderline mucinous tumors of ovaries. Read More

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http://dx.doi.org/10.1016/j.gore.2020.100572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182719PMC

Gastric Glomus Tumor: A Clinicopathologic and Immunohistochemical Study of 21 Cases.

Biomed Res Int 2020 3;2020:5637893. Epub 2020 Apr 3.

Department of Pathology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.

Gastric glomus tumors (GGTs) are rare mesenchymal tumors. Most glomus tumors occur in the distal parts of the extremities. Here, we retrospectively analyzed the features of GGTs from two institutions. Read More

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http://dx.doi.org/10.1155/2020/5637893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157787PMC

Characteristics and Early Diagnosis of Gastric Cancer Discovered after Eradication.

Gut Liver 2020 Apr 24. Epub 2020 Apr 24.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

The prevalence of gastric cancer after eradication (GCAE) is increasing dramatically in Japan. GCAE has characteristic features, and we must understand these features in endoscopic examinations. Differentiated cancer types were frequently found after eradication and included characteristic endoscopic features such as reddish depression (RD). Read More

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http://dx.doi.org/10.5009/gnl19418DOI Listing

Clinical significance of serum neuron-specific enolase in gastric adenocarcinoma.

Medicine (Baltimore) 2020 Apr;99(16):e19829

China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.

As a biomarker, neuron-specific enolase (NSE) has been widely recognized in the diagnosis of benign diseases and malignant tumors. This study aimed to investigate the potential diagnostic value of NSE in patients with gastric adenocarcinoma.Serum levels of the NSE were compared between 219 patients with gastric adenocarcinoma and 298 healthy individuals, NSE and clinicopathological parameters were analyzed. Read More

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http://dx.doi.org/10.1097/MD.0000000000019829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220193PMC

[Comparison of short-term efficacy between robotic and 3D laparoscopic-assisted D2 radical distal gastrectomy for gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Apr;23(4):350-356

School of Medicine, Nankai University, Tianjin 300071, China; Department of General Surgery, Institute of General Surgery, Chinese PLA General Hospital, Beijing 100853, China.

To compare short-term efficacy of robotic versus 3D laparoscopic-assisted D2 radical distal gastrectomy in gastric cancerpatients and those with different body mass index (BMI). A retrospective cohort study was performed. Inclusion criteria:(1) gastric cancer proved by preoperative pathological results and tumor location was suitable for D2 radical distal gastrectomy; (2) no distal metastases such as in liver, kidney or abdominal cavity, and no direct invasion to the pancreas or colon on preoperative imaging; (3) postoperative pTNM stage ranged from I to III; (4) no conversion to open surgery or change of surgical procedure during operation; (5) complete clinicopathological data. Read More

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http://dx.doi.org/10.3760/cma.j.cn.441530-20200224-00085DOI Listing

Hispanic/Latino Patients with Gastric Adenocarcinoma Have Distinct Molecular Profiles Including a High Rate of Germline Variants.

Cancer Res 2020 Jun 8;80(11):2114-2124. Epub 2020 Apr 8.

Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

Hispanic/Latino patients have a higher incidence of gastric cancer and worse cancer-related outcomes compared with patients of other backgrounds. Whether there is a molecular basis for these disparities is unknown, as very few Hispanic/Latino patients have been included in previous studies. To determine the genomic landscape of gastric cancer in Hispanic/Latino patients, we performed whole-exome sequencing (WES) and RNA sequencing on tumor samples from 57 patients; germline analysis was conducted on 83 patients. Read More

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2918DOI Listing
June 2020
9.329 Impact Factor

Outcomes of Gastric Resection in the Establishment of a Comprehensive Oncologic Robotic Program.

J Surg Res 2020 Aug 26;252:30-36. Epub 2020 Mar 26.

H. Lee Moffitt Cancer Center & Research Institute, Department of Gastrointestinal Oncology, Tampa, Florida. Electronic address:

Background: Robotic-assisted gastrectomy is increasingly utilized for the treatment of gastric malignancies. However, the benefits of robotic surgery have been questioned. This study describes short-term outcomes in the establishment of a comprehensive robotic program for gastric malignancies. Read More

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http://dx.doi.org/10.1016/j.jss.2020.01.023DOI Listing

Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature.

BMC Med Genet 2020 03 14;21(1):52. Epub 2020 Mar 14.

Section of General Surgery and Gastrointestinal Surgery, Department of Surgery I, Faculdade de Medicina do ABC, Avenida Lauro Gomes, 2000, Santo André/São Paulo, CEP 09060-870, Brazil.

Background: Birt-Hogg-Dubé syndrome (BHDS) is a rare autosomal dominant genodermatosis characterized by benign growth of the hair follicles, the presence of pulmonary cysts, spontaneous pneumothorax, and bilateral renal tumors that are usually hybrid oncocytic or multifocal chromophobe renal cell carcinoma. The diagnosis is confirmed by the presence of a pathogenic variant in the tumor suppressor folliculin (FLCN) gene mapped at 17p11.2. Read More

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http://dx.doi.org/10.1186/s12881-020-0991-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071710PMC

[A Case of Laparoscopic Local Resection of the Stomach for an Inflammatory Myofibroblastic Tumor].

Gan To Kagaku Ryoho 2019 Dec;46(13):2054-2056

Dept. of Surgery, Funabashi Chuo Hospital.

A 52-year-old man underwent upper gastrointestinal endoscopy screening that identified a submucosal tumor in the gastric fornix, and a solid tumor with a maximum diameter of 35mm was suspected based on abdominal computed tomography. An endoscopic ultrasound-guided fine needle aspiration biopsy showed spindle-shaped cells with KIT, CD34, desmin, and S-100 all testing negative. Based on the diagnosis of a gastrointestinal stromal tumor, subtotal gastrectomy was performed laparoscopically. Read More

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December 2019

A case of a gastric granular cell tumor preoperatively diagnosed and successfully treated by single-incision laparoscopic surgery.

Surg Case Rep 2020 Feb 27;6(1):44. Epub 2020 Feb 27.

Department of Surgery, Kindai University Faculty of Medicine, 377-2 Ohno-higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

Background: Granular cell tumors (GCT) in the gastrointestinal tract are rare. Herein, we describe a case of a gastric GCT diagnosed preoperatively by endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNAB) and successfully resected by single-incision laparoscopic surgery (SILS).

Case Presentation: A 46-year-old Japanese woman had a tumor located in the angle of the stomach that was approximately 1. Read More

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http://dx.doi.org/10.1186/s40792-020-00809-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046852PMC
February 2020

Is subtotal gastrectomy feasible for the treatment of gastric stump cancer located at the anastomotic site after distal gastrectomy for benign lesions?

World J Surg Oncol 2020 Feb 27;18(1):43. Epub 2020 Feb 27.

Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Beijing, 100021, China.

Background: Total gastrectomy (TG) is a widely accepted procedure for treating gastric stump cancer (GSC). However, subtotal gastrectomy (SG) would benefit elective patients with GSC. The aim of this study was to clarify the safety and long-term prognosis of SG in treating GSC after distal gastrectomy for benign lesions. Read More

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http://dx.doi.org/10.1186/s12957-020-01821-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047362PMC
February 2020

[Treatment strategy for gastrointestinal tumor under the outbreak of novel coronavirus pneumonia in China].

Authors:
Y H Chen J S Peng

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Feb;23(2):I-IV

Department of Gastrointestinal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China.

The outbreak of the novel coronavirus pneumonia (NCP) has become a public health emergency in China. Chinese authorities and health agencies had devoted great efforts to control this disease. As surgeons specialized in the treatment of gastrointestinal tumors, we should always be aware of the prevention for NCP and incorporate this awareness into every detail of clinical practice. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1671-0274.2020.02.001DOI Listing
February 2020

[Calcifying fibrous tumor: a clinicopathological analysis of 32 cases].

Zhonghua Bing Li Xue Za Zhi 2020 Feb;49(2):129-133

Department of Pathology, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou 450003, China.

To investigate the clinicopathological characteristics, histogenesis, immunophenotypes, molecular genetic characteristics, diagnosis and differential diagnosis of calcifying fibrous tumors (CFT). A total of 32 cases of CFT (22 cases from Henan Provincial People's Hospital and 10 cases from PLA Army Medical Center) diagnosed between June 2009 and February 2019 were reviewed. The clinical and pathologic data were analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2020.02.005DOI Listing
February 2020

Gastric schwannoma with giant ulcer and lymphadenopathy mimicking gastric cancer: a case report.

BMC Gastroenterol 2020 Feb 14;20(1):36. Epub 2020 Feb 14.

Department of Nuclear Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.

Background: Gastric schwannomas are rare benign tumors originating from the intramuscular plexus of the stomach and account for just 2.6% of gastric mesenchymal tumors. Gastric schwannoma (GS) with a surface ulcer is very rare. Read More

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http://dx.doi.org/10.1186/s12876-020-01186-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023701PMC
February 2020

Mutation Analysis of Colorectal and Gastric Carcinomas Originating from Adenomas: Insights into Genomic Evolution Associated with Malignant Progression.

Cancers (Basel) 2020 Jan 31;12(2). Epub 2020 Jan 31.

Department of Medical Informatics, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul 06591, Korea.

Small malignant tumor foci arising from benign lesions are rare but offer a unique opportunity to investigate the genomic evolution that occurs during malignant transformation. In this study, we analyzed 11 colorectal and 10 gastric adenoma-carcinoma pairs, each of which represented malignant tumors (carcinomas) embedded in benign lesions (adenomas) found in the same patient. Whole-exome sequencing revealed that mutation abundance was variable across different cases, but comparable between adenoma-carcinoma pairs. Read More

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http://dx.doi.org/10.3390/cancers12020325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072232PMC
January 2020

Gastric schwannoma: a diagnosis that should be known in 2019.

J Surg Case Rep 2020 Jan 13;2020(1):rjz382. Epub 2020 Jan 13.

General Surgery Department, Military Hospital Mohamed V, Rabat 10000, Morocco.

Gastric schwannoma (GS) is a rare neoplasm of the stomach deriving from Schwann cells of the peripheral nerves in the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing and asymptomatic. Read More

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http://dx.doi.org/10.1093/jscr/rjz382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963168PMC
January 2020

Diagnostic value of negative enrichment and immune fluorescence hybridization for intraperitoneal free cancer cells of gastric cancer.

Chin J Cancer Res 2019 Dec;31(6):945-954

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.

Objective: To explore the intraperitoneal free cancer cell (IFCC) detection value of negative enrichment and immune fluorescence hybridization (NEimFISH) on chromosomes (CEN) 8/17.

Methods: To verify the reliability of NEimFISH, 29 gastric cancer tumors, their adjacent tissues and greater omental tissues were tested. Our study then included 105 gastric cancer patients for IFCC. Read More

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http://dx.doi.org/10.21147/j.issn.1000-9604.2019.06.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955163PMC
December 2019
0.932 Impact Factor

A Novel Method of Nasojejunal Feeding and Gastric Decompression Using a Double Lumen Silicone Tube for Upper Gastrointestinal Obstruction.

Surg Laparosc Endosc Percutan Tech 2020 Apr;30(2):106-110

Department of Surgery, Hospital Sultanah Aminah, Johor Bahru.

Background: Provision of enteral nutrition with jejunal feeding in upper gastrointestinal obstruction is highly recommended. Access to jejunum can be obtained surgically, percutaneously, or endoscopically. Our institution routinely and preferentially utilizes a silicone nasojejunal tube that is inserted past the obstruction endoscopically. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000754DOI Listing
April 2020
0.938 Impact Factor

[Gastrointestinal glomus tumors: a clinicopathological analysis of fifteen cases].

Zhonghua Bing Li Xue Za Zhi 2020 Jan;49(1):22-27

Department of Pathology, the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

To investigate the clinicopathological features, diagnosis and differential diagnosis of gastrointestinal glomus tumors (GIGT). Totally 15 cases of GIGT were collected at the First Affiliated Hospital, Zhengzhou University, from January 2011 to June 2018. The clinicopathological features, immunophenotype, BRAF V600E mutation and prognosis were retrospectively analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2020.01.005DOI Listing
January 2020

Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients.

Yonsei Med J 2020 Jan;61(1):15-19

Department of Clinical Laboratory, Binhai County People's Hospital, Jiangsu, China.

Purpose: The purpose of this study was to assess the diagnostic and prognostic value of serum progastrin-releasing peptide (ProGRP) in patients with gastric cancer (GC).

Materials And Methods: A total of 150 patients with GC (89 males and 61 females) were recruited, including those with stage I (n=28), stage II (n=33), stage III (n=50), and stage IV (n=39) disease; 50 healthy controls and 66 patients with benign gastric diseases were also enrolled. Levels of serum ProGRP, carcinoembryonic antigen (CEA), and carbohydrate antigen 72-4 (CA72-4) were measured in all subjects. Read More

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http://dx.doi.org/10.3349/ymj.2020.61.1.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938777PMC
January 2020
1.263 Impact Factor

Gastric gastrointestinal stromal tumours (2-5 cm): Correlation of CT features with malignancy and differential diagnosis.

Eur J Radiol 2020 Feb 11;123:108783. Epub 2019 Dec 11.

Department of General Surgery, Peking University First Hospital, Peking University, 8 Xi ShiKu Street, Beijing 100034, People's Republic of China. Electronic address:

Purpose: The purpose of this study was to investigate the computed tomography (CT) features of 2-5 cm gastric gastrointestinal stromal tumors (GISTs), schwannomas and leimyomas which have close relationship with malignancy evaluation and differential diagnosis.

Method: Seventy-six patients with pathologically confirmed gastric submucosal tumors (SMTs) between 2-5 cm were included in this study, including 60 GISTs, 10 schwannomas and 6 leiomyomas. CT imaging features were reviewed and quantitative parameters including CT values during nonenhanced phase (CTV-N), portal phase (CTV-P) and delayed phase (CTV-D) were recorded. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.108783DOI Listing
February 2020

[Clinical application of convolutional neural network in pathological diagnosis of metastatic lymph nodes of gastric cancer].

Zhonghua Wai Ke Za Zhi 2019 Dec;57(12):934-938

Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, Qingdao 266055, China.

To examine the value and clinical application of convolutional neural network in pathological diagnosis of metastatic lymph nodes of gastric cancer. Totally 124 patients with advanced gastric cancer who underwent radical gastrectomy plus D2 lymphadenectomy at Affiliated Hospital of Qingdao University from July 2016 to December 2018 were selected in the study. According to the chronological order, the first 80 cases were served as learning group. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2019.12.012DOI Listing
December 2019

[Gastric neuroendocrine tumors].

Khirurgiia (Mosk) 2019 (12):111-120

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia PA, USA.

Gastrointestinal neuroendocrine tumors are rare neoplasms. Currently, incidence of gastric neuroendocrine tumors (gNETs) is being significantly increased. There are 3 groups of gNETs: types I, II and III. Read More

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http://dx.doi.org/10.17116/hirurgia2019121111DOI Listing
December 2019

Multiparametric MRI and F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions.

Eur Radiol 2020 Mar 28;30(3):1634-1643. Epub 2019 Nov 28.

Department of Radiology, Seoul National University Hospital, 101 Daehakro, Jongno-gu, Seoul, Korea.

Objectives: To investigate whether multiparametric magnetic resonance imaging (MRI) and F-fluorodeoxyglucose positron emission tomography (PET) can be helpful in differentiating gastrointestinal stromal tumors (GISTs) from non-GISTs and high-risk GISTs from low-risk GISTs.

Methods: This retrospective study included 56 patients with pathologically confirmed GISTs (n = 39), leiomyoma (n = 8), schwannoma (n = 5), heterotopic pancreas (n = 3), and glomus tumor (n = 1) who underwent MRI and/or PET examinations. Two radiologists reviewed MRI regarding location, shape, contour, growth pattern, margin, signal intensity (SI) on T1- (T1WI) and T2-weighted images (T2WI), degree and pattern of enhancement, hemorrhage, and necrosis. Read More

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http://dx.doi.org/10.1007/s00330-019-06534-9DOI Listing

Posterior enucleation of the pancreatic head: an alternative route of access for parenchyma-sparing pancreatic resection.

Langenbecks Arch Surg 2019 Dec 11;404(8):1023-1028. Epub 2019 Nov 11.

Department of Surgery, Klinik Beau-Site, Hirslanden, Schänzlihalde 1, 3013, Bern, Switzerland.

Background: Enucleation has become an alternative treatment in benign or low-malignant cystic tumors, including intraductal papillary mucinous neoplasms (IPMN). For enucleation to be a safe alternative to the standard procedures, there must be good access to the resection area. In this report, we present such a route for dorsally situated IPMNs. Read More

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http://dx.doi.org/10.1007/s00423-019-01835-5DOI Listing
December 2019

Prognostic Nutritional Index and Neutrophil-to-Lymphocyte Ratio Are Respectively Associated with Prognosis of Gastric Cancer with Liver Metatasis Undergoing and without Hepatectomy.

Biomed Res Int 2019 7;2019:4213623. Epub 2019 Oct 7.

Department of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, 150 Haping Road, Nangang District, Harbin 150081, China.

To clarify the efficacy of hepatectomy for gastric cancer liver metastasis (GCLM) and to investigate the association between prognostic nutrition index (PNI) or neutrophil-to-lymphocyte ratio (NLR) and prognosis of GCLM undergoing or without hepatectomy. We retrospectively studied 374 patients with GCLM. The ROC curve was used to determine the optimal cut-off of PNI and NLR. Read More

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http://dx.doi.org/10.1155/2019/4213623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800959PMC

Plasma desacyl ghrelin-to-acyl ghrelin ratio is a predictor of postoperative complications and prognosis after pancreaticoduodenectomy.

Oncol Lett 2019 Nov 6;18(5):4974-4983. Epub 2019 Sep 6.

Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki 889-1692, Japan.

The current study aimed to clarify the significance of the preoperative desacyl ghrelin (DG)-to-acyl ghrelin (AG) ratio in patients undergoing pancreaticoduodenectomy (PD). Ghrelin, a peptide hormone mainly produced in the stomach, possesses unique functions. Recently, studies have determined the involvement of plasma gherlin in certain postoperative outcomes, particularly in surgical resections of the stomach. Read More

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http://dx.doi.org/10.3892/ol.2019.10821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781775PMC
November 2019
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Expression of SMAD4 is Retained in Most Gynecologic Tumors with Mucinous Differentiation.

Int J Gynecol Pathol 2019 Sep 27. Epub 2019 Sep 27.

University of Miami/Jackson Health System, Jackson Memorial Hospital (S.A., K.A.) Miller School of Medicine, University of Miami (A.P.) Miami, Florida.

SMAD4 is a tumor suppressor gene that plays a role in cancer initiation and progression. A few studies have explored the value of immunohistochemistry for SMAD4 in gynecologic neoplasms, mainly in the ovary. However, literature is sparse when it comes to other sites such as endometrium and cervix, as well as in benign and borderline ovarian mucinous neoplasms. Read More

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http://dx.doi.org/10.1097/PGP.0000000000000637DOI Listing
September 2019
3 Reads

Management of gastric glomus tumor: A case report.

Medicine (Baltimore) 2019 Sep;98(38):e16980

Department of General Surgery, The People's Hospital of Suzhou New District, Suzhou, Jiangsu, China.

Rationale: Gastric glomus tumor (GGT) is a rare gastrointestinal tumor and its preoperative imaging features are significant to make a correct diagnosis, while the assessment of the pathological and immunohistochemical characteristics of the specimen are the main methods used for its diagnosis. This study introduces the clinical uniqueness, endoscopic ultrasonography, radiology, histology and immunohistochemistry results of a patient with GGT to discuss the imaging and clinico-pathological features, diagnosis and differential diagnosis of GGT.

Patient Concerns: The patient expressed a complaint concerning an "intermittent abdominal pain for 4 months". Read More

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http://dx.doi.org/10.1097/MD.0000000000016980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756591PMC
September 2019
2 Reads

Clinical characteristics and surgical treatment of schwannomas of the esophagus and stomach: A case series and systematic review.

World J Gastrointest Oncol 2019 Sep;11(9):750-760

Department of Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City14080,

Background: Gastrointestinal schwannomas are slow-growing benign mesenchymal neoplasms that originate from Schwann cells of the nerve sheath of Auerbach´s plexus or less frequently from Meissner´s plexus. The main differential diagnosis of gastric schwannomas are the gastrointestinal stromal tumors (GISTs), which are classified by their immunohistochemistry. The treatment of choice for gastric schwannomas is surgery where laparoscopy plays an important role. Read More

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http://dx.doi.org/10.4251/wjgo.v11.i9.750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755107PMC
September 2019
4 Reads

Risk factors for Mallory-Weiss Tear during endoscopic submucosal dissection of superficial esophageal neoplasms.

World J Gastroenterol 2019 Sep;25(34):5174-5184

Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.

Background: Adverse events during endoscopic submucosal dissection (ESD) of superficial esophageal neoplasms, such as perforation and bleeding, have been well-documented. However, the Mallory-Weiss Tear (MWT) during esophageal ESD remains under investigation.

Aim: To investigate the incidence and risk factors of the MWT during esophageal ESD. Read More

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http://dx.doi.org/10.3748/wjg.v25.i34.5174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747285PMC
September 2019
1 Read

Association Between Intra-Tumoral Immune Response and Programmed Death Ligand 1 (PD-L1) in Gastric Cancer.

Med Sci Monit 2019 Sep 14;25:6916-6921. Epub 2019 Sep 14.

Central Laboratory, Bayannur Hospital, Linhe, Inner Mongolia, China (mainland).

BACKGROUND Targeting of PD-1/PD-L1 immune checkpoints exhibits excellent clinical outcomes in numerous types of solid tumors, including gastric cancer. However, the tumor microenvironment of gastric cancer is very complex and the association of PD-L1 with the tumor microenvironment in gastric cancer is still not clear. MATERIAL AND METHODS This study analyzed the characteristics of PD-L1 expression and used immunohistochemistry to assess CD8 and CD4 tumor-infiltrating leucocytes (TILs) in 478 cases of gastric cancer compared with the expression patterns in 70 matched adjacent tissues, and 32 cases of benign gastric tissues. Read More

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http://dx.doi.org/10.12659/MSM.916432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759503PMC
September 2019
2 Reads

Pediatric gastroenteropancreatic neuroendocrine tumor: A case report and review of the literature.

Medicine (Baltimore) 2019 Sep;98(37):e17154

Gastroenterology and Endoscopy Unit, University Hospital of Parma, University of Parma, Parma, Italy.

Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of epithelial neoplasms originating from the diffuse neuroendocrine cell system of the gastrointestinal tract and pancreas. They are very rare, especially in pediatric age, and vary widely in terms of clinical presentation, malignant potential, and prognosis.

Patient Concerns: A 9 years' old, white female child presented with abdominal pain and diarrhea mixed with bright red blood lasting 2 days followed by hematemesis. Read More

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http://dx.doi.org/10.1097/MD.0000000000017154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750332PMC
September 2019
4 Reads

Exosomal miR-1246 in serum as a potential biomarker for early diagnosis of gastric cancer.

Int J Clin Oncol 2020 Jan 10;25(1):89-99. Epub 2019 Sep 10.

Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, No.121, Jiangjiayuan Road, Nanjing, 210011, China.

Background: Gastric cancer (GC) patients are usually diagnosed in advanced stages which results in high mortality. This study aimed to identify novel circulating miRNAs as biomarkers for the early detection of GC.

Methods: Candidate miRNA was identified after integrated analysis of two Gene Expression Omnibus (GEO) datasets and clinical serum samples. Read More

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http://dx.doi.org/10.1007/s10147-019-01532-9DOI Listing
January 2020

Benign gastrobronchial fistula following oesophagectomy in a patient presenting with respiratory failure.

BMJ Case Rep 2019 Sep 4;12(9). Epub 2019 Sep 4.

Intensive Care Department, Universitair Ziekenhuis Gent, Gent, Belgium.

Benign gastrobronchial fistula (GBF) is a rare but potentially life-threatening complication of oesophagectomy for malignancy. We present a case of GBF post Ivor-Lewis surgery manifesting as pulmonary sepsis and type II respiratory failure. Clues to the diagnosis were persistent hypercapnia despite high minute ventilation, aspiration of gastric content through the endotracheal tube and accumulation of air in the nasogastric drainage bag. Read More

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http://dx.doi.org/10.1136/bcr-2018-228537DOI Listing
September 2019
1 Read

INTRODUCTION OF THE NEW LYMPHOPARIETAL INDEX FOR GASTRIC CANCER PATIENTS.

Arq Bras Cir Dig 2019 Aug 26;32(2):e1441. Epub 2019 Aug 26.

Department of Surgery, Universidad de Chile Clinical Hospital, Santiago, Chile.

Background: The identification of prognostic factors of gastric cancer (GC) has allowed to predict the evolution of patients.

Aim: Assess the reliability of the lymphoparietal index in the prediction of long-term survival in GC treated with curative intent.

Method: Prospective study of the Universidad de Chile Clinical Hospital, between May 2004 and May 2012. Read More

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http://dx.doi.org/10.1590/0102-672020190001e1441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713052PMC
August 2019
2 Reads

Automated classification of gastric neoplasms in endoscopic images using a convolutional neural network.

Endoscopy 2019 12 23;51(12):1121-1129. Epub 2019 Aug 23.

Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.

Background: Visual inspection, lesion detection, and differentiation between malignant and benign features are key aspects of an endoscopist's role. The use of machine learning for the recognition and differentiation of images has been increasingly adopted in clinical practice. This study aimed to establish convolutional neural network (CNN) models to automatically classify gastric neoplasms based on endoscopic images. Read More

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http://dx.doi.org/10.1055/a-0981-6133DOI Listing
December 2019
4 Reads
5.053 Impact Factor

Incidental Finding of Gastric Schwannoma in a Renal Failure Patient - Managed by a Minimally Invasive Procedure: Report of a Rare Case.

Am J Case Rep 2019 Aug 22;20:1241-1244. Epub 2019 Aug 22.

Department of Surgery, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ, USA.

BACKGROUND Schwannomas are benign tumors originating from any nerve with a Schwann cell sheath. It is an extremely rare tumor, accounting for 0.2% of all gastrointestinal tumors and 4% of all benign tumors of the stomach. Read More

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http://dx.doi.org/10.12659/AJCR.916487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717397PMC
August 2019
7 Reads

Efficacy of Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Gastric Subepithelial Tumors Located in the Cardia.

Dig Dis Sci 2020 02 13;65(2):583-590. Epub 2019 Aug 13.

Department of Gastroenterology, Asan Medical Center, Asan Digestive Disease Research Institute, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.

Background: In cases of subepithelial tumors (SETs) located in the cardiac area, a preoperative histologic diagnosis might be helpful in determining the requirement of surgery.

Aim: To investigate the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) in gastric SETs located in the cardia.

Methods: The data of 107 patients who underwent EUS-FNB, from 2012 to 2017, for tissue sampling of gastric SETs located in the cardia were collected. Read More

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http://dx.doi.org/10.1007/s10620-019-05774-5DOI Listing
February 2020
6 Reads

Oxyntic gland neoplasm of the stomach: expanding the spectrum and proposal of terminology.

Mod Pathol 2020 02 2;33(2):206-216. Epub 2019 Aug 2.

Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Gastric neoplasms exhibiting oxyntic gland differentiation typically are composed of cells with mild cytonuclear atypia differentiating to chief cells and to a lesser extent, parietal cells. Such tumors with atypical features have been reported also and terminology for this entity remains a matter of considerable debate. We analyzed and classified 26 tumors as oxyntic gland neoplasms within mucosa (group A, eight tumors) and with submucosal invasion. Read More

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http://dx.doi.org/10.1038/s41379-019-0338-1DOI Listing
February 2020
6 Reads