4,217 results match your criteria Benign Gastric Tumors


Gastric Schwannoma, a benign neoplasm hiding as gastrointestinal stromal tumour.

J Pak Med Assoc 2022 Jun;72(6):1211-1213

Department of Pathology, Liaquat National Hospital, Karachi, Pakistan.

Gastric Schwannomas are rare, submucosal mesenchymal tumours arising from the nerve plexus of the Gut wall. They have an incidence rate of 0.2% of all Gastric tumours. Read More

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Endoscopic Ultrasonography-guided Gastrojejunostomy for Patients with Gastric Outlet Obstruction and Pyloric Metal Stent Dysfunction.

Korean J Gastroenterol 2022 Jun;79(6):260-264

Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.

A 52-year-old woman with a gastric outlet obstruction (GOO) caused by pyloric cancer underwent pyloric endoscopic self-expandable metal stent (SEMS) insertion. She presented with abdominal distension 40 days later. The SEMS was dysfunctional, and endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) was performed using an endoscopic nasobiliary drainage tube. Read More

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Accessory Spleen: A Rare and Incidental Finding in the Stomach Wall.

Cureus 2022 May 13;14(5):e24977. Epub 2022 May 13.

Gastroenterology and Hepatology, MetroHealth Medical Center, Cleveland, USA.

An accessory spleen is splenic tissue located separately from the anatomical location of the spleen and is a rare phenomenon. It can be found within the gastrointestinal tract. Clinically, accessory spleens are benign but can be misidentified as reactive lymph nodes or malignant gastrointestinal tumors. Read More

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Gastrointestinal tract schwannomas and brief review of literature.

Turk J Surg 2021 Dec 31;37(4):408-412. Epub 2021 Dec 31.

Department of Pathology, University of Health Sciences Istanbul Training and Research Hospital, Istanbul, Turkey.

Schwannomas originating from Schwann cells arise from the peripheral nerve sheath and are slow-growing, benign tumors that originate mostly from the mesenchyme. It appears equally in both sexes. Schwannomas are often seen in the 3rd and 5th decades of life. Read More

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December 2021

Gastric Schwannoma: A Case Report and Literature Review.

Cureus 2022 May 6;14(5):e24785. Epub 2022 May 6.

Gastroenterology, Parkview Medical Center, Pueblo, USA.

Gastric schwannomas (GS) are very rare spindle cell, submucosal mesenchymal tumors that arise from Schwann cells of nerve plexuses in the stomach wall. They are usually benign but can become malignant and metastasize to other organs. Surgical resection with biopsy is the gold standard for diagnosis and management of GS. Read More

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Laparoscopic-assisted endoscopic full-thickness resection of a large gastric schwannoma: A case report.

World J Gastrointest Surg 2022 Apr;14(4):362-369

Department of Gastroenterology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310000, Zhejiang Province, China.

Background: Schwannomas, also known as neurinomas, are benign tumors derived from Schwann cells. Gastrointestinal schwannomas are rare and are most frequently reported in the stomach. They are usually asymptomatic and are difficult to diagnose preoperatively; however, endoscopy and imaging modalities can provide beneficial preliminary diagnostic data. Read More

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Gastric Glomus Tumor: A Rare Cause of Acute Blood Loss Anemia.

Cureus 2022 Apr 26;14(4):e24511. Epub 2022 Apr 26.

Hospital Medicine, Albert Einstein College of Medicine, New York City, USA.

Gastric glomus tumors (GGTs) are rare mesenchymal neoplasms that arise from cells of the glomus body. These occur in the submucosa of the gastric wall and are usually benign in nature. However, it is difficult to predict tumor behavior due to the lack of reliable histological features. Read More

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Difference in the prevalence of advanced colon adenoma between patients with gastric neoplasm and healthy people: A STROBE-compliant study.

Medicine (Baltimore) 2022 May 27;101(21):e29308. Epub 2022 May 27.

Department of Internal Medicine, Dong-A University Hospital, Dong-A University College of Medicine, Busan, South Korea.

Abstract: We compared the prevalence of adenoma and cancerous colon polyps in patients undergoing endoscopic removal or gastric surgery for gastric adenoma or gastric cancer and in healthy individuals.The medical records of 707 patients with gastric neoplasm and 798 age- and sex-matched healthy subjects were retrospectively analyzed between January 2010 and July 2018. The clinicopathological characteristics, prevalence of colorectal neoplasm diagnosed by colonoscopy, and risk factors for colorectal polyps were also investigated. Read More

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Splenic vessels preserving versus Warshaw technique in spleen preserving distal pancreatectomy: A systematic review and meta-analysis.

Int J Surg 2022 Jul 20;103:106686. Epub 2022 May 20.

Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, Sichuan Province, China. Electronic address:

Background: Spleen-preserving distal pancreatectomy is widely used to remove benign or low-grade malignant neoplasms located in the pancreatic body and tail. Both splenic vessels preserving (SVP-DP) and splenic vessels ligating (Warshaw technique [WT]) distal pancreatectomy are safe and effective methods but which technique is superior remains controversial. Thus, this study aimed to evaluate the clinical outcomes of patients who underwent both methods. Read More

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Differential expression of metallothionein and p21 in gastric cancer and some precursor lesions.

Eur Rev Med Pharmacol Sci 2022 May;26(9):3100-3108

Department of Pathology, Department of Hepatology and Gastroenterology, Theodor Bilharz Research Institute (TBRI), Giza, Egypt.

Objective: Gastric cancer (GC) is a heterogeneous disease with molecular diversity between and within tumors; therefore, searching for altered genes within this cancer is mandatory to reach the proper individualized targeted therapy. Expressions of Metallothionein (MT) and p21 are not uniform in various types of cancers and their predictive value in GC is controversial. This study aimed to assess the role of MT and p21 in intestinal-type GC and some of its precursor lesions. Read More

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Small intestinal myxoma presented with bowel obstruction, a rare case report.

Int J Surg Case Rep 2022 Jun 14;95:107180. Epub 2022 May 14.

Department of Pathology, Medical School, Fasa University of Medical Sciences, Fasa, Iran. Electronic address:

Introduction: Myxomas are rare benign mesenchymal neoplasms and mostly occur in cardiac atrium and with lower prevalence, appear in sinonasal tract, gnathic bone, skin and joints. Benign primary tumors of the small intestine are quite unusual accounting about 3% of all the gastrointestinal tract neoplasms.

Presentation Of Case: In this report, we present a rare case of small intestinal myxoma in a 43-year-old man complicated by ileoileal intussusception causing bowel obstruction. Read More

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Value of F-FDG PET/CT for differentiating diagnosis between malignant and benign primary gastric gastrointestinal mesenchymal tumors: a single-center retrospective study.

J Gastrointest Oncol 2022 Apr;13(2):637-646

Department of Nuclear Medicine, Fujian Medical University Cancer Hospital & Fujian Cancer Hospital, Fuzhou, China.

Background: Malignant primary gastric gastrointestinal stromal tumors (gGISTs) without treatment with imatinib are prone to bleeding and peritoneum implantation during operation. Therefore, preoperative assessment of the malignant potential of gGIST is essential. The use of F-fluorodeoxyglucose (F-FDG) positron emission tomography (PET) combined with computed tomography (PET/CT) as a non-invasive tool for diagnosis, staging and prognosis evaluation in oncology, may also be useful for gGISTs. Read More

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[A case of juvenile gastric polyposis with gastric cancer successfully treated by laparoscopic total gastrectomy -review of 36 reported cases in Japan].

Nihon Shokakibyo Gakkai Zasshi 2022 ;119(5):438-445

Department of Surgery, Yodogawa Christian Hospital.

A 43-year-old woman was suffering from epigastric pain. Her gastroscopy revealed polyposis of the stomach, and her biopsy revealed a hyperplastic polyp. During the 18-month follow-up, the polyps proliferated, and the patient was referred to our institute for further investigation and treatment. Read More

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Clinicopathological study of gastric schwannoma and review of related literature.

BMC Surg 2022 May 10;22(1):159. Epub 2022 May 10.

General Surgery, Cancer Center, Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China, 310014.

Background: This study aimed to investigate the clinical features, diagnostic criteria, treatment options, and prognosis of patients with gastric schwannoma (GS).

Methods: We collected the clinical data of all patients pathologically diagnosed with GS in Zhejiang Provincial People's Hospital from May 2012 to October 2021.

Results: A total of 26 cases of GS were analyzed clinicopathologically, where the sizes of the tumor were found to be in the range of 1-6 cm (mean: 3. Read More

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Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.

Gastroenterology 2022 Jun 26;162(7):2063-2085. Epub 2022 Apr 26.

Veterans Affairs Medical Center, White River Junction, Vermont; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.

The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis syndrome, the PTEN hamartoma tumor syndrome (including Cowden's syndrome and Bannayan-Riley-Ruvalcaba syndrome), and hereditary mixed polyposis syndrome. Diagnoses are based on clinical criteria and, in some cases, confirmed by demonstrating the presence of a germline pathogenic variant. Read More

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Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer.

Gastrointest Endosc 2022 Jun 26;95(6):1025-1047. Epub 2022 Apr 26.

Veterans Affairs Medical Center, White River Junction, Vermont; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.

The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis syndrome, the PTEN hamartoma tumor syndrome (including Cowden's syndrome and Bannayan-Riley-Ruvalcaba syndrome), and hereditary mixed polyposis syndrome. Diagnoses are based on clinical criteria and, in some cases, confirmed by demonstrating the presence of a germline pathogenic variant. Read More

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Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.

Am J Gastroenterol 2022 06 26;117(6):846-864. Epub 2022 Apr 26.

Veterans Affairs Medical Center, White River Junction, Vermont, USA.

The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis syndrome, the PTEN hamartoma tumor syndrome (including Cowden's syndrome and Bannayan-Riley-Ruvalcaba syndrome), and hereditary mixed polyposis syndrome. Diagnoses are based on clinical criteria and, in some cases, confirmed by demonstrating the presence of a germline pathogenic variant. Read More

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Diagnosis value of miR-181, miR-652, and CA72-4 for gastric cancer.

J Clin Lab Anal 2022 Jun 21;36(6):e24411. Epub 2022 Apr 21.

Department of Gastroenterology, First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.

Purpose: To find a useful disease marker for early diagnosis of gastric cancer, we tried to explore the expression of serum miR-181, miR-652, and carbohydrate antigen 72-4 (CA72-4).

Patients And Methods: According to clinical pathologic stages, 112 patients with gastric cancer were divided into early gastric cancer group (n = 60) and advanced gastric cancer group (n = 52), stage I-II (n = 65), and stage III-IV (n = 47). Another 50 cases of gastric benign lesions and 40 healthy controls were also selected. Read More

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Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases.

JAMA Oncol 2022 Jun;8(6):835-844

Center for Precision Medicine, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Knowledge about the spectrum of diseases associated with hereditary cancer syndromes may improve disease diagnosis and management for patients and help to identify high-risk individuals.

Objective: To identify phenotypes associated with hereditary cancer genes through a phenome-wide association study.

Design, Setting, And Participants: This phenome-wide association study used health data from participants in 3 cohorts. Read More

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Computed tomography features and clinicopathological characteristics of gastric glomus tumor.

BMC Gastroenterol 2022 Apr 9;22(1):174. Epub 2022 Apr 9.

Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou, 450052, Henan Province, China.

Background: Gastric glomus tumor (GGT) is a rare neoplasm that is difficult to distinguish from other gastric submucosal tumors due to a lack of diagnostic experience. The goal of this study was to better understand GGT by looking at its clinicopathological features, computed tomography (CT) features, and differential diagnosis.

Methods: The clinical data and CT findings of 21 pathologically confirmed GGT patients were examined. Read More

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Imaging findings of gastrointestinal tract tumors in children and adolescents.

Insights Imaging 2022 Mar 22;13(1):51. Epub 2022 Mar 22.

Department of Radiology/Subdivision of Pediatric Radiology, Hacettepe University School of Medicine Ankara, Sıhhiye, 06100, Ankara, Turkey.

Gastrointestinal (GI) tract tumors are rarely seen in children and adolescents, and can easily be misdiagnosed. Lymphoma is the most frequent GI tract tumor, and the common locations are ileum and ileocecal area. GI tract tumors may present as large heterogeneous mass lesions. Read More

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infection treatment in the United States: clinical consequences and costs of eradication treatment failure.

Expert Rev Gastroenterol Hepatol 2022 Apr 1;16(4):341-357. Epub 2022 Apr 1.

Division of Gastroenterology, University of California San Diego, La Jolla, California, USA.

Introduction: (Hp) is causal in benign and malignant gastrointestinal diseases. Accordingly, current guidelines recommend Hp eradication in patients with active infection. Unfortunately, treatment failure is common, exposing patients to complications associated with persistent Hp infection and consequences of repeated treatment, including promotion of antibiotic resistance. Read More

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Endoscopic Resection of Upper Gastrointestinal Subepithelial Tumours: Our Clinical Experience and Results.

Prague Med Rep 2022 ;123(1):20-26

Department of General Surgery, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey.

Upper gastrointestinal subepithelial tumours (SETs) are generally asymptomatic and clinically insignificant and have malign, borderline and benign variants. In advanced endoscopic procedures, histopathological diagnosis and endoscopic resection are possible and feasible. In this study, we examined our approach to upper gastrointestinal subepithelial tumours and our clinical results. Read More

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Oxaliplatin related multiple focal nodular hyperplasia mimicking metastasis from a gastric cancer.

J Oncol Pharm Pract 2022 Feb 28:10781552221084617. Epub 2022 Feb 28.

Department of Radiology, 103564Hospital Universitario "Dr José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.

Introduction: The FOLFOX6 scheme is a combination drug chemotherapy that contains calcium leucovorin (folinic acid), fluorouracil, and oxaliplatin, the chronic use of chemotherapy with oxaliplatin can progress to focal nodular hyperplasia (FNH), which is a benign hepatic lesion.

Case Report: We present a case of a 26- year-old female diagnosed with an ovarian mixed germ cell tumor with extension to the peritoneum, treated with 12 cycles in 9 months with neoadjuvant chemotherapy FOLFOX 6 scheme and oophorectomy. A three-year follow-up CT showed three nodular and hypervascular hepatic lesions suspicious of metastatic disease; an MRI with liver-specific contrast confirmed the diagnosis of FNH. Read More

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February 2022

Gastric polyps: a 10-year analysis of 18,496 upper endoscopies.

BMC Gastroenterol 2022 Feb 19;22(1):70. Epub 2022 Feb 19.

Gastroenterology and Hepatology Department, Habib Thameur Hospital, Tunis, Tunisia.

Background/aims: Gastric polyps (GPs) are usually asymptomatic lesions of the upper gastrointestinal tract observed in 1-3% of esophagogastroduodenoscopies (EGD). Most GPs are benign. The aim of this study was to precise the frequency of different types of gastric polyps in our population, and to analyze their possible association with other factors. Read More

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February 2022

Diagnostic Value of Tumor Markers in Peritoneal Lavage Fluid for Peritoneal Metastasis from Colorectal Cancer.

Ann Clin Lab Sci 2022 Jan;52(1):95-100

Department of General Surgery, Jiujiang University Clinical Medical College, Jiujiang University Hospital, Jiujiang City, Jiangxi Province, China

Objective: To investigate the diagnostic value of tumor markers in peritoneal lavage fluid in the diagnosis of peritoneal metastasis from colorectal cancer.

Methods: One hundred eighty-six patients with colorectal cancer and 15 patients with benign disease who underwent surgical treatment were included. The abdominal cavity and pelvis of the patients were lavaged with 200 ml of normal saline immediately after abdominal cavity incision or pneumoperitoneum establishment. Read More

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January 2022

Endoscopic management of subepithelial lesions including neuroendocrine neoplasms: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Endoscopy 2022 04 18;54(4):412-429. Epub 2022 Feb 18.

Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

1: ESGE recommends endoscopic ultrasonography (EUS) as the best tool to characterize subepithelial lesion (SEL) features (size, location, originating layer, echogenicity, shape), but EUS alone is not able to distinguish among all types of SEL.Strong recommendation, moderate quality evidence. 2: ESGE suggests providing tissue diagnosis for all SELs with features suggestive of gastrointestinal stromal tumor (GIST) if they are of size > 20 mm, or have high risk stigmata, or require surgical resection or oncological treatment. Read More

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[Clinicopathological characteristics of natural killer cell enteropathy: report of two cases and review of literature].

Zhonghua Bing Li Xue Za Zhi 2022 Feb;51(2):108-113

Department of Pathology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To study the clinicopathological and genetic features of natural killer (NK)-cell enteropathy for better understanding of this rare disease and prevention of its misdiagnosis. Two cases of NK-cell enteropathy were diagnosed in the First Affiliated Hospital of Zhengzhou University, China from October 2017 to February 2021. The clinical characteristics, morphology, immunohistochemistry, Epstein-Barr virus-encoded RNA (EBER) in situ hybridization and T cell receptor gene rearrangement were analyzed. Read More

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February 2022

Robotic-assisted surgery for esophageal submucosal tumors: a single-center case series.

Updates Surg 2022 Jun 11;74(3):1043-1054. Epub 2022 Feb 11.

Mainz University, Johannes Gutenberg Universitat Mainz, Mainz, Germany.

Esophageal submucosal tumors (SMTs) are rare heterogenous clinical entities. The surgical resection can be performed in different surgical approaches. However, the robotic surgical strategy is poorly documented in the treatment of SMTs. Read More

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