5,434 results match your criteria Benign Cervical Lesions


Presentation of External Ear Rosai-Dorfman Disease With Laryngeal Involvement.

Ear Nose Throat J 2021 May 11:1455613211016704. Epub 2021 May 11.

Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.

Rosai-Dorfman disease (RDD) is a rare benign systemic histiocytic proliferation characterized by massive lymph node enlargement and sometimes associated with extranodal involvement. Even though it is considered to be benign, death can occur depending on the extent and location. Our case highlights a primary extranodal site of the right pinna with extension through the Eustachian tube to the subglottis. Read More

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Scalp malignant trichilemmal tumour with bony erosion: a new clinical entity.

BMJ Case Rep 2021 May 10;14(5). Epub 2021 May 10.

Oral and Maxillofacial Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.

Trichilemmoma is a benign tumour which arises from the hair follicle root sheath, and commonly occurs in the head and neck area. Malignant transformation and locally aggressive growth of these tumours are very rare. Surgical excision remains the mainstay of management, with scarce evidence for other treatment modalities. Read More

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The current value of quantitative shear wave sonoelastography in parotid gland tumors.

Gland Surg 2021 Apr;10(4):1374-1386

Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsklinikum Erlangen, University of Erlangen-Nürnberg (FAU), Erlangen, Germany.

Background: The preoperative differentiation between salivary gland tumor entities using computed tomography, magnetic resonance imaging (MRI) and ultrasound (US) is still limited. Biopsies are often regarded as indispensable for properly characterizing these various lesions. The aim of this study was to analyze the value of acoustic radiation force impulse (ARFI) sonoelastography as an US differentiation tool when examining parotid gland (PG) lesions. Read More

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Pediatric intraosseous schwannoma in maxillary sinus: A case report with review of literature.

J Oral Maxillofac Pathol 2020 Sep-Dec;24(3):542-547. Epub 2021 Jan 9.

Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Andhra Pradesh, India.

Neurilemmoma has been defined as a benign, encapsulated neoplasm that arises in the nerve fiber. It originates from the proliferation of Schwann cells in the perineurium causing displacement and compression of the adjacent nerve. This neoplasm is composed primarily of Schwann cells in a poorly collagenized stroma. Read More

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January 2021

A rare case of intramuscular angioma involving the medial rectus muscle.

Orbit 2021 May 6:1-6. Epub 2021 May 6.

Department of Ophthalmology and Pathology, University of Ottawa and the Ottawa Hospital, Ottawa, Ontario, Canada.

Benign benign vascular tumors (e.g., hemangiomas) and malformations are commonly encountered lesions in all ages of life, especially in infancy and childhood. Read More

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Intramuscular hemangioma in the zygomaticus minor muscle: a case report and literature review.

Arch Craniofac Surg 2021 Apr 20;22(2):115-118. Epub 2021 Apr 20.

TN Plastic and Reconstructive Surgery Clinic, Seoul, Korea.

Intramuscular hemangioma is a rare vascular benign proliferation that can occur within any muscle, particularly in the trunk and extremities. In the head and neck region, the masseter muscle is most commonly involved, followed by the periorbital and sternocleidomastoid muscles. Diagnosing intramuscular hemangioma is challenging because there are no characteristic symptoms; instead, magnetic resonance imaging is the best imaging modality to diagnose these lesions. Read More

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Neurothekeoma: Another differential in the diagnosis of a subungual swelling.

Foot (Edinb) 2021 Apr 19;47:101809. Epub 2021 Apr 19.

Department of Pathology, Altnagelvin Hospital, Glenshane Road, Londonderry, Northern Ireland, BT47 6SB, UK.

Case: Lesions, which commonly grow and protrude beneath the distal end of a toe nail and present to the podiatrist or foot and ankle surgeon, include subungual exostosis or enchondroma and a Nora lesion. Neurothekeoma is a benign dermal tumour of the peripheral nerve sheath that usually affects the skin of the head, neck, shoulders and arms. It occurs less commonly in the lower limbs and has only been reported twice in a subungual location. Read More

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The genetic diversity of human papillomavirus types from the species Gammapapillomavirus 15: HPV135, HPV146, and HPV179.

PLoS One 2021 6;16(5):e0249829. Epub 2021 May 6.

Faculty of Medicine, Institute of Microbiology and Immunology, University of Ljubljana, Ljubljana, Slovenia.

Objectives: To determine the prevalence, viral load, tissue tropism, and genetic variability of novel human papillomavirus (HPV) type 179, which is etiologically associated with sporadic cases of common warts in immunocompromised patients, and phylogenetically related HPV types 135 and 146.

Methods: The representative collection of 850 HPV-associated clinical samples (oral/nasopharyngeal/anal, archival specimens of oral/oropharyngeal/conjunctival/cervical/skin cancer, benign lesions of the larynx/conjunctiva/skin, and eyebrows), obtained from immunocompetent individuals, was tested for the presence of HPV179, HPV135, and HPV146 using type-specific real-time PCRs. To assess the genetic diversity of the HPVs investigated in the non-coding long control region (LCR), several highly sensitive nested PCR protocols were developed for each HPV type. Read More

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Cervical intradural intramedullary collision tumor of schwannoma and hemangioblastoma origin.

Surg Neurol Int 2021 14;12:155. Epub 2021 Apr 14.

Department of Neurosurgery, Mayo Clinic, Scottsdale, Arizona, United States.

Background: Primary spinal tumors are rare benign lesions that represent around 2-4% of all central nervous system neoplasms.[1,2] Intradural intramedullary tumors are predominately glial in origin and are most commonly astrocytomas or ependymomas. Intradural extramedullary tumors, on the other hand, are usually neurofibromas, schwannomas, or meningiomas. Read More

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Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Follicular Differentiation.

Int J Mol Sci 2021 Apr 30;22(9). Epub 2021 Apr 30.

Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.

Neoplasms derived from follicular tissue are extremely rare. Clinically, they are reported as non-symptomatic, slow-growing nodules. These lesions are mainly benign, but the malignant type can occur. Read More

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Accuracy, predictability and prognostic implications of fine needle aspiration biopsy for parotid gland tumors: A retrospective case series.

Clin Otolaryngol 2021 May 4. Epub 2021 May 4.

Department of Otolaryngology - Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel.

Objective: To evaluate the precision and utility of Fine-needle aspiration (FNA) in differentiating between benign and malignant parotid tumors, and the implications of FNA results on management and outcomes.

Design: Retrospective case series.

Setting: Tertiary medical center. Read More

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Application of ultrasound elastography in obstetrics and gynecology

Orv Hetil 2021 05 2;162(18):690-695. Epub 2021 May 2.

3 Eastern Virginia Medical School, Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Norfolk, VA, United States of America.

Összefoglaló. Az ultrahang-elasztográfia az elmúlt évek során egyre növekvő figyelmet kapott a lágyszövetek elaszticitásának vizsgálatában. A módszer használatát az teszi szükségessé, hogy egyes, a mechanikai tulajdonságaikban különböző szövetek hasonló echogenitásúak lehetnek, valamint hogy egy adott szövet megváltozott struktúrája vagy mechanikai tulajdonsága nem minden esetben jár együtt a szövet hagyományos ultrahangképének megváltozásával. Read More

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Vertebral pneumatocyst - A systematic review.

World Neurosurg 2021 Apr 29. Epub 2021 Apr 29.

Neurochirurgische Praxis Bad Homburg Zeppelinstr. 24 61352 Bad Homburg Germany.

Introduction: Intraosseous pneumatocyst refers to gas-filled cystic lesions inside bone. While ilium and sacrum are the commonest locations for pneumatocysts, vertebral pneumatocysts are rare. Various theories have proposed to explain the etiopathogenesis of vertebral pneumatocysts and the most widely accepted theory is the extension of air from intervertebral disc or joint spaces into the pneumatocyst cavity. Read More

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Using Dynamic Features for Automatic Cervical Precancer Detection.

Diagnostics (Basel) 2021 Apr 17;11(4). Epub 2021 Apr 17.

Signal Processing Laboratory (LTS5), École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Cervical cancer remains a major public health concern in developing countries due to financial and human resource constraints. Visual inspection with acetic acid (VIA) of the cervix was widely promoted and routinely used as a low-cost primary screening test in low- and middle-income countries. It can be performed by a variety of health workers and the result is immediate. Read More

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Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix.

Cancers (Basel) 2021 Apr 6;13(7). Epub 2021 Apr 6.

Molecular Pathology of Cancer Group, Navarrabiomed, Complejo Hospitalario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, 31008 Pamplona, Spain.

No therapeutic targets and molecular biomarkers are available in cervical cancer (CC) management. In other cancer types, micro-RNA-877-3p (miR-877-3p) has been associated with events relevant for CC development. Thus, we aimed to determine miR-877-3p role in CC. Read More

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Expression of Oncogene in Benign, Malignant and Borderline Melanocytic Tumors-Unmasking the Wolf in Sheep's Clothing?

Cancers (Basel) 2021 Apr 1;13(7). Epub 2021 Apr 1.

Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, D-66421 Homburg, Germany.

oncogene located at chromosomal region 3q26 encodes for a transmembrane protein of the endoplasmic reticulum (ER) and is expressed at high levels in numerous human malignancies. overexpression has been associated with worse prognosis and high risk for lymphatic and distant metastases in head and neck cancer, cervical cancer, hepatocellular cancer, and lung cancer. However, its role in the development and tumor biology of melanocytic lesions has not been investigated so far. Read More

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[Clinicopathological features and prognosis of nodal nevi].

Zhonghua Bing Li Xue Za Zhi 2021 May;50(5):494-499

Department of Pathology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University; Institute of Pathology, Fudan University, Shanghai 200032, China.

To investigate the clinicopathological characteristics, differential diagnosis and prognosis of nodal nevi (NN). Eighteen cases of NN diagnosed at Fudan University Shanghai Cancer Center, Shanghai, China from 2009 to 2019 were collected. The clinicopathological characteristics and follow-up data were retrospectively analyzed. Read More

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Oncocytic papillary cystadenoma of the larynx: comparative study of ten cases and review of the literature.

Eur Arch Otorhinolaryngol 2021 Apr 28. Epub 2021 Apr 28.

Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine in Hradec Kralove, Charles University, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.

Objective: Oncocytic papillary cystadenomas (OPCs) of the larynx are rare benign cystic lesions that usually present as supraglottic masses arising from the laryngeal ventricles. OPCs are found in patients older than 60 years, with a female predominance. Symptoms vary from asymptomatic to hoarseness, dyspnea, and dysphagia; often, they mimic a laryngocele. Read More

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Diagnostic Accuracy of Fine-Needle Aspiration Cytology in Head and Neck Lesions from a Tertiary Health Facility in Southwestern Nigeria.

Niger Med J 2020 Nov-Dec;61(6):303-306. Epub 2020 Dec 19.

Department of Pathology, University of Ibadan/University College Hospital, Ibadan, Nigeria.

Background: Fine-needle aspiration cytology (FNAC) is widely employed as an initial investigative tool in the diagnosis of various lesions in the body, however, it is limited in the provision of precise architectural detail of lesions. This is said to be responsible for the wide variation in the documented usefulness and accuracy relative to histopathology. This study aimed to correlate cytopathological and histopathological examination (HPE) of head and neck lesions, and assess the usefulness and accuracy of FNAC in our center. Read More

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December 2020

Correlation Between Fine Needle Aspiration Cytology (FNAC) and Permanent Histopathology Results in Salivary Gland Masses.

Cureus 2021 Mar 18;13(3):e13976. Epub 2021 Mar 18.

College of Medicine, Department of Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU.

Objective Fine-needle aspiration cytology (FNAC) has been widely accepted as a diagnostic safe method for preoperative assessment of salivary gland lesions. This diagnostic tool is inexpensive, easy to perform, relatively painless and it provides useful information to differentiate between benign and malignant salivary gland tumors that helps in the management and surgical planning. This study was undertaken to compare FNAC results with permanent histopathological findings of salivary gland tumors in order to assess its diagnostic accuracy. Read More

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Branchial Cleft Cyst Harbors Metastatic Papillary Thyroid Carcinoma.

Cureus 2021 Mar 17;13(3):e13940. Epub 2021 Mar 17.

Department of Otolaryngology, Ear, Nose and Throat (ENT) South, Dothan, USA.

Branchial cleft cysts are congenital anomalies which develop in utero, most commonly arising from the second branchial cleft. They are often asymptomatic lateral neck masses but can enlarge and become symptomatic in the setting of infection. The cystic cavity can form a potential space which can harbor infection and, in rare cases, malignant spread of primary tumors. Read More

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Diverse clinical presentations of tubercular parotitis in children: case series with review of literature.

Sudan J Paediatr 2021 ;21(1):67-75

Department of Otolaryngology and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India.

Tuberculosis of the parotid gland is a rare entity in children. Manifestations can vary from acute parotitis to indolent benign parotid lesions, abscesses and fistulas in the parotid region. Diagnosis is challenging in the absence of constitutional symptoms and essentially non-contributory test reports. Read More

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January 2021

Multimodal ultrasound imaging of primary thyroid schwannoma: A case report.

Medicine (Baltimore) 2021 Apr;100(16):e25517

Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, China.

Rationale: Primary schwannoma of the thyroid gland is very rare, and its preoperative diagnosis is difficult.

Patient Concerns: We report the case of a thyroid nodule in an 18-year-old woman, who presented with a mass in her left neck with stiffness and normal thyroid function. However, the patient complained of numbness in her left upper extremity, and ultrasound (US) features were suspicious of malignancy. Read More

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An updated review of the epidemiological factors associated with recurrent respiratory papillomatosis.

Laryngoscope Investig Otolaryngol 2021 Apr 28;6(2):226-233. Epub 2021 Jan 28.

Department of Head and Neck Surgery Ronald Reagan UCLA Medical Center Los Angeles California USA.

Objectives: To identify studies evaluating the epidemiology of recurrent respiratory papillomatosis (RRP), including patient demographics, human papillomavirus (HPV) immunology, clinical course, surgical and medical treatments, and psychosocial factors.

Methods: A systematic literature search through PubMed was performed to identify studies evaluating the epidemiological factors associated with RRP. All studies were screened through a priori selection criteria using the titles and abstracts. Read More

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Magnetic resonance imaging of salivary gland tumours: Key findings for imaging characterisation.

Eur J Radiol 2021 Apr 10;139:109716. Epub 2021 Apr 10.

Department of Experimental and Clinical Biomedical Sciences, Radiodiagnostic Unit n. 2, Careggi University Hospital, Largo Brambilla 3, Florence, 50134, Italy. Electronic address:

Salivary gland tumours are rare, representing only 3% of all head and neck neoplasms, with the parotid gland being the most common site (80 %). The risk of malignancy is inversely proportional to the size of the gland: lesions arising in the sublingual or minor salivary glands are more likely to be malignant, whereas parotid gland neoplasms are mostly benign. Fine needle aspiration cytology and core needle biopsy are considered the most accurate modalities for the diagnosis of a salivary gland neoplasm; however, they are not always conclusive due to procedural sampling errors and for the presence of a cytological / histological overlap between benign and malignant tumours. Read More

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[Cranio-facial-cervical and subglottic hemangioma with respiratory symptoms. A therapeutic emergency].

An Sist Sanit Navar 2021 Apr 28;44(1):113-117. Epub 2021 Apr 28.

Cirugía Pediátrica. Complejo Hospitalario de Navarra. Pamplona. España..

We describe the case of a 41-day-old infant with a left craniofacial cervical and subglottic hemangioma with respira-tory symptoms. Although infantile hemangiomas are occasional benign vascular tumors that appear predominantly on the skin, 1-2% of patients may have airway lesions that can sometimes cause potentially life-threatening respiratory condi-tions. The decision was made to immediately commence treatment with propranolol, without waiting to complete the exten-sion and syndromic diagnoses. Read More

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[HPV vaccination and the prevention of genital warts and precancerous lesions-current evidence and evaluation].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2021 May 13;64(5):590-599. Epub 2021 Apr 13.

Lehrstuhl für Epidemiologie, Fakultät für Sport- und Gesundheitswissenschaften, Technische Universität München, Georg-Brauchle-Ring 56, 80992, München, Deutschland.

Human papillomaviruses (HPVs) can cause both benign and malignant tumors. To date, more than 200 HPV types have been discovered, of which 12 are currently classified as high risk for cervical cancer. HPV types that affect the anogenital tract are sexually transmitted. Read More

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Is Transoral Robotic Surgery the Best Surgical Treatment for Lingual Thyroid?: A Case-Report and Literature Review.

Ann Otol Rhinol Laryngol 2021 Apr 10:34894211007251. Epub 2021 Apr 10.

Otorhinolaryngology and Head and Neck Surgery Department, Toulouse University Hospital, Hôpital Larrey, Toulouse, France.

Objectives: To highlight the specific outcomes of the current surgical procedures for lingual thyroid excision, for benign and malignant lesions.

Methods: We carried out a systematic review of surgical treatments of lingual thyroid, according to the PRISMA method. We conducted our literature search in PubMed and Ovid. Read More

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Laryngeal Manifestations of Intractable Singultus.

Cureus 2021 Mar 6;13(3):e13730. Epub 2021 Mar 6.

Otolaryngology - Head and Neck Surgery, Mayo Clinic, Jacksonville, USA.

Hiccup is a common phenomenon experienced by almost everyone in life. Although the exact physiology of this phenomenon remains unknown, it is associated with multiple central and peripheral etiologic causes. Vocal fold granulomas are benign laryngeal lesions typically caused by iatrogenic trauma, voice misuse, or chronic irritation. Read More

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Patterns of Recurrence of Phonotraumatic Vocal Fold Lesions Suggest Distinct Mechanisms of Injury.

Laryngoscope 2021 Apr 9. Epub 2021 Apr 9.

The Sean Parker Institute for the Voice, Department of Otolaryngology-Head & Neck Surgery, Weill Cornell Medicine, New York, New York, USA.

Objectives/hypothesis: To examine patterns of recurrence of benign phonotraumatic vocal fold lesions over time for insights into pathophysiology.

Study Design: Case series with mathematical modeling.

Methods: Medical records and stroboscopic exams of adults who underwent microlaryngoscopic resection of phonotraumatic vocal fold lesions over a 13-year period were reviewed for time to recurrence after surgery. Read More

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