4,807 results match your criteria Benign Cervical Lesions


Watchful waiting in carefully selected metachronous cystadenolymphomas of the parotid gland: a reliable option?

Br J Oral Maxillofac Surg 2019 Apr 20. Epub 2019 Apr 20.

Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.

The aim of this study was to evaluate the potential of watchful waiting in the treatment of metachronous cystadenolymphomas, taking the experience of our department into consideration. All patients suspected of having a metachronous cystadenolymphoma, and who had a minimum follow-up time of 12 months, were studied (n = 26). Data about the growth rate, number of lesions, and symptoms of inflammation were recorded. Read More

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http://dx.doi.org/10.1016/j.bjoms.2018.12.018DOI Listing

Endoscopic Treatment of Isolated Sphenoid Sinus Disease in Children.

Ear Nose Throat J 2019 Apr 23:145561319841227. Epub 2019 Apr 23.

2 Imaging Center, Beijing Children's Hospital, Capital Medical University, Xi Cheng District, Beijing, People's Republic of China.

In this article, we explore the disease spectrum and clinical characteristics of and the diagnosis and endoscopic approach to treating isolated sphenoid sinus disease (ISSD) in children. To these ends, we review a case series of 19 patients (mean age: 8.1 ± 4. Read More

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http://dx.doi.org/10.1177/0145561319841227DOI Listing

Risk factors of malignant fluorodeoxyglucose-avid lymph node on preablation positron emission tomography in patients with papillary thyroid cancer undergoing radioiodine ablation therapy.

Medicine (Baltimore) 2019 Apr;98(16):e14858

Department of Nuclear Medicine, Chonnam National University Hospital.

F-18 fluorodeoxyglucose (FDG)-avid metastatic lesions are associated with a poor response to radioiodine ablation therapy (RIT) in papillary thyroid cancer (PTC). This study evaluated the significance of preablative FDG positron emission tomography (PET) for the assessment of risk factors and frequency of malignant FDG-avid lymph nodes in patients with PTC undergoing RIT.The study included 339 consecutive patients (mean age 46. Read More

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http://dx.doi.org/10.1097/MD.0000000000014858DOI Listing
April 2019
1 Read

Unique manifestation of a multifocal adult rhabdomyoma involving the soft palate-case report and review of literature.

J Surg Case Rep 2019 Apr 16;2019(4):rjz116. Epub 2019 Apr 16.

Department of Oral, Maxillofacial and Plastic Surgery, University Medical Center Mainz, Mainz, Germany.

Extracardiac adult rhabdomyoma is a rare benign tumor, which mainly occurs in the head and neck region and originates from striated muscle tissue. We report a 64-year-old male with simultaneous diagnosis of three adult rhabdomyomas including the soft palate and performed a review the literature on multifocal adult rhabdomyoma (mARM). Including the present case, 27 mARM with a range of 2-7 lesions per patient were collected. Read More

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http://dx.doi.org/10.1093/jscr/rjz116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465952PMC

Oral intramuscular hemangioma: report of three cases.

J Cutan Pathol 2019 Apr 21. Epub 2019 Apr 21.

Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.

Intramuscular hemangioma represents less than 1% of all hemangiomas. In the head and neck region, it occurs mostly in the masseter, temporalis and sternocleidomastoid muscles. Besides its infiltrative growth pattern and several worrisome histological features, such as increased mitotic activity, plumpness of the nuclei, intraluminal papillary projections or perineural infiltration, the lesion is benign, and complete surgical excision is the preferred treatment for such oral lesions. Read More

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http://dx.doi.org/10.1111/cup.13482DOI Listing

Multicentric, multifocal, and recurrent osteoid osteoma of the hip: first case report.

BMC Musculoskelet Disord 2019 Apr 16;20(1):171. Epub 2019 Apr 16.

Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy.

Background: Osteoid osteoma is a benign bone-forming tumour, which very unfrequently has multifocal or multicentric presentation. We report the first known case of a multicentric, multifocal and recurrent osteoid osteoma treated using radiofrequency ablation.

Case Presentation: A 39-year-old man with two-year history of left hip pain was admitted at our Institution. Read More

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12891-019-2552-xDOI Listing
April 2019
2 Reads

Air Injection and Transillumination in Phonosurgery: A Novel Technique.

J Voice 2019 Apr 12. Epub 2019 Apr 12.

Istanbul Training and Research Hospital, Otolaryngology Head and Neck Surgery Department Istanbul, Turkey.

Objectives/hypothesis: The goal of this study was to introduce two novel techniques in phonomicrosurgery, air injection (AIR), and transillumination (TI), to improve the diagnosis and surgical excision of pathological tissue in vocal folds during suspension laryngoscopy while preserving the healthy tissue as much as possible.

Study Design: Prospective clinical case series.

Methods: Thirty-four patients with benign vocal cord lesions who underwent phonomicrosurgery between January 2016 and May 2017 were evaluated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08921997183052
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http://dx.doi.org/10.1016/j.jvoice.2019.03.009DOI Listing
April 2019
2 Reads

The Management of Giant Cerviofacial Lymphatic Malformations in Children.

J Craniofac Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Otolaryngology-Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University.

Objective: Lymphatic malformations (LMs) are rare and benign diseases. This article aimed to present a series of surgically treated giant cervicofacial LMs in children.

Methods: A retrospective analysis of giant cervicofacial LMs (tumor diameter greater than 10 cm) in children over the past 8 years was performed in our department. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005520DOI Listing
April 2019
2 Reads

Comparison of micro-insulated needle radiofrequency and carbon dioxide laser ablation for the treatment of syringoma.

Dermatol Ther 2019 Apr 9:e12912. Epub 2019 Apr 9.

Department of Dermatology, National Medical Center, Seoul, Korea.

Syringoma is a benign adnexal tumor originating from the intradermal eccrine ducts and predominantly occurs in women at puberty or later in life. We present a case of a 30-year-old woman with a 2-year history of syringoma on her neck and axillar region. She was treated with two devices in a split manner. Read More

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http://dx.doi.org/10.1111/dth.12912DOI Listing
April 2019
1 Read

High-Resolution MRI Microscopy Coil Assessment of Parotid Masses.

Ear Nose Throat J 2019 Apr 8:145561319839898. Epub 2019 Apr 8.

1 Department of Radiology, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA.

The goal of this study was to determine whether high-resolution magnetic resonance imaging (MRI) microscopy coil imaging can improve the depiction parotid masses. A total of 14 parotid masses, including 7 salivary neoplasms, 2 abnormal lymph nodes, and 5 benign cystic lesions were imaged with T2-weighted and fat-suppressed postcontrast T1-weighted sequences using a 47-mm diameter microscopy coil in addition to conventional MRI sequences acquired with a conventional head and neck neurovascular coil. Compared to conventional parotid MRI sequences, microscopy coil images provided better definition of the margins of neoplasms, provide more detailed definition of lymph node morphology, and better depict certain cyst contents in the superficial portions of the parotid gland. Read More

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http://dx.doi.org/10.1177/0145561319839898DOI Listing
April 2019
4 Reads

Computer-Aided Design and Computer-Aided Manufacturing Versus Conventional Free Fibula Flap Reconstruction in Benign Mandibular Lesions: An Italian Cost Analysis.

J Oral Maxillofac Surg 2019 Mar 13. Epub 2019 Mar 13.

Practitioner in Maxillofacial Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Milan; Professor of Maxillofacial Surgery, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

Purpose: The cost of computer-aided design and computer-aided manufacturing (CAD-CAM) technology has created obstacles for its widespread use despite its several advantages. This study compared the cost of CAD-CAM technology with that of the conventional freehand technique in fibula reshaping for mandibular reconstruction.

Materials And Methods: A retrospective comparative study was conducted at the Maxillofacial and Dental Unit of the Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico (Milan, Italy). Read More

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http://dx.doi.org/10.1016/j.joms.2019.03.003DOI Listing
March 2019
1 Read

Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer.

EBioMedicine 2019 Apr 4. Epub 2019 Apr 4.

Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA; Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address:

Background: Trefoil factors (TFF1, TFF2, and TFF3) are small secretory molecules that recently have gained significant attention in multiple studies as an integral component of pancreatic cancer (PC) subtype-specific gene signature. Here, we comprehensively investigated the diagnostic potential of all the member of trefoil family, i.e. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.03.056DOI Listing
April 2019
2 Reads

Identification of Hürthle cell cancers: solving a clinical challenge with genomic sequencing and a trio of machine learning algorithms.

BMC Syst Biol 2019 Apr 5;13(Suppl 2):27. Epub 2019 Apr 5.

Department of Research & Development, Veracyte, Inc, 6000 Shoreline Court, Suite 300, South San Francisco, CA, 94080, USA.

Background: Identification of Hürthle cell cancers by non-operative fine-needle aspiration biopsy (FNAB) of thyroid nodules is challenging. Resultingly, non-cancerous Hürthle lesions were conventionally distinguished from Hürthle cell cancers by histopathological examination of tissue following surgical resection. Reliance on histopathological evaluation requires patients to undergo surgery to obtain a diagnosis despite most being non-cancerous. Read More

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https://bmcsystbiol.biomedcentral.com/articles/10.1186/s1291
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http://dx.doi.org/10.1186/s12918-019-0693-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450053PMC
April 2019
3 Reads

Primary intraosseous mucoepidermoid carcinoma of the mandible: radiographic evolution and clinicopathological features.

BMJ Case Rep 2019 Apr 3;12(4). Epub 2019 Apr 3.

Oral & Maxillofacial Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

Mucoepidermoid carcinoma (MEC) can be rarely found as a primarily intraosseous lesion and mistaken for other intraosseous or odontogenic pathology. A 65-year-old man had a poorly defined radiolucency distal to the left mandibular second molar root. Periapical radiographs demonstrated a minor radiolucency from 2. Read More

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http://dx.doi.org/10.1136/bcr-2018-224612DOI Listing
April 2019
2 Reads

Endoscopic anatomical study of the trans-lateral molar approach to the infratemporal fossa.

Eur Arch Otorhinolaryngol 2019 Apr 3. Epub 2019 Apr 3.

Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, 510630, Guangdong, China.

Background: The infratemporal fossa (ITF) is located deep in the skull base. Recently, the endoscopic transoral approach has enabled maxillofacial surgeons to access the ITF using a less invasive approach compared to the traditional transfacial and endonasal endoscopic approaches.

Objective: The present study aims to provide maxillofacial surgeons with new data concerning direct endoscopic measurement and precise anatomical topography features of the endoscopic trans-lateral molar approach to ITF by comparing the endoscopic and regional anatomy of ITF. Read More

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http://dx.doi.org/10.1007/s00405-019-05409-5DOI Listing
April 2019
5 Reads

Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.

Cancer Med 2019 Apr 1. Epub 2019 Apr 1.

Department of Diagnostic and Biomedical Sciences, University of Texas School of Dentistry at Houston, Houston, Texas.

Background: Matrix metalloproteinases-20 (MMP20) expression is widely regarded as tooth specific, with expression limited to dental hard tissues. Recently, we reported MMP20 expression and interaction with dentin sialophosphoprotein (DSPP), a member of the Small Integrin Binding Ligand N-linked Glycoproteins (SIBLINGs), in human oral squamous cell carcinoma (OSCC) and dysplastic oral premalignant lesions (OPLs), suggesting a role for MMP20-DSPP interaction in oral carcinogenesis.

Methods: This study aimed to survey the expression of MMP20 and its cognate DSPP partner in the breast, colon, prostate, thyroid, and cervical neoplasms. Read More

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http://dx.doi.org/10.1002/cam4.2117DOI Listing
April 2019
1 Read

Indeterminate nodules by the Bethesda system for reporting thyroid cytopathology in Israel: Frequency, and risk of malignancy after reclassification of follicular thyroid neoplasm with papillary-like features.

Eur J Surg Oncol 2019 Mar 15. Epub 2019 Mar 15.

Institute of Endocrinology, Metabolism, and Hypertension, Tel Aviv Sourasky Medical Center, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.

Objective: We aimed to determine the frequency and risk of malignancy (ROM) for indeterminate thyroid nodules, categories III (B3) and IV (B4) of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC), at a large institution in Israel. Additionally, we investigated the impact of redefining follicular neoplasm with papillary-like nuclear features (NIFTP) as non-malignant on malignancy rates.

Methods: In this retrospective study of all thyroid fine needle aspirations (FNAs) performed at Tel Aviv-Sourasky Medical Center between January 2013 and December 2015, we assessed ROM for B3 and B4 nodules. Read More

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http://dx.doi.org/10.1016/j.ejso.2019.03.015DOI Listing
March 2019
2 Reads

Adenomyosis:A Clinico-pathological Study.

West Afr J Med 2019 Jan-Apr;36(1):88-92

Department of Histopathology, Jos University Teaching Hospital, Jos, Plateau State, Nigeria.

Background: Adenomyosis is defined by the presence within the myometrium of benign endometrial glands and stroma. Several theories have evolved to explain the pathogenesis of adenomyosis. A third of adenomyosis cases are asymptomatic. Read More

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March 2019
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Office-Based 532-Nanometer Pulsed Potassium-Titanyl-Phosphate Laser Procedures in Laryngology.

Otolaryngol Clin North Am 2019 Mar 26. Epub 2019 Mar 26.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Voice Center, University of Texas Health Science Center-San Antonio, 8431 Fredricksburg Road, San Antonio, TX 78229, USA.

With fiber-based lasers that may be passed via the working channel of a flexible laryngoscope, in-office laser laryngeal surgery has become possible. The potassium-titanyl-phosphate laser has several features that make it ideal for laryngeal surgery, and it is now the laser of choice for in-office management of a variety of laryngeal lesions. Its applications have expanded significantly since its introduction, with reports of new indications continuing to appear in the literature. Read More

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http://dx.doi.org/10.1016/j.otc.2019.02.011DOI Listing
March 2019
1 Read

[Giant verrucous nevus in a 15-year old girl: about a case].

Pan Afr Med J 2018 24;31:50. Epub 2018 Sep 24.

CNAM (ex Institut Marchoux), Bamako, Mali.

Verrucous nevus is a benign tumor showing a linear pattern on Blaschko lines. It is caused by mosaic mutations of the receptor FGFR3 gene. It manifests as an aesthetic disfigurement, but individuals even experience functional complications due to itchiness. Read More

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http://dx.doi.org/10.11604/pamj.2018.31.50.11408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430852PMC
April 2019
1 Read

Dermatofibrosarcoma protuberans: clinicopathologic presentation in Nigerians.

Pan Afr Med J 2018 12;31:25. Epub 2018 Sep 12.

Department of Oral and Maxillofacial Surgery, College of Medicine University of Lagos, Nigeria.

Introduction: Dermatofibrosarcoma protuberance (DFSP) is in general a rare low grade malignant sarcoma and possesses a tendency for local recurrence. It has a site predilection for the trunk. Occurrence in the facial area is extremely rare. Read More

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http://dx.doi.org/10.11604/pamj.2018.31.25.13665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430858PMC
April 2019
1 Read

Cervical Lymph Node Schwannoma-An Unexpected Diagnosis.

Clin Pathol 2019 Jan-Dec;12:2632010X19829239. Epub 2019 Feb 27.

Department of Endocrinology, Diabetes and Metabolism, Santa Maria Hospital, Lisbon, Portugal.

Introduction: Schwannomas-Schwann cells-originating tumors-may develop in many locations. However, primary schwannomas arising within lymph nodes are extremely rare, with only a few cases described to this date in the English literature. For the intranodal location, most of the cases are described in the abdominal cavity. Read More

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http://dx.doi.org/10.1177/2632010X19829239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429639PMC
February 2019
1 Read

Unilateral internal jugular vein phlebectasia in an adult: Management and one year follow-up.

SAGE Open Med Case Rep 2019 18;7:2050313X19836351. Epub 2019 Mar 18.

Department of Family and Community Medicine, Unaizah College of Medicine, Qassim University, Unaizah, Saudi Arabia.

Phlebectasia describes an anomalous, fusiform dilatation of a vein. In the neck region, the internal and external jugular veins are mostly affected. To our knowledge, this is the first case in Saudi Arabia of internal jugular phlebectasia affecting an adult female. Read More

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http://dx.doi.org/10.1177/2050313X19836351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423680PMC
March 2019
4 Reads

Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group.

Int J Hyperthermia 2019 26;36(1):376-382. Epub 2019 Mar 26.

aa Division of Interventional Radiology , IEO, European Institute of Oncology IRCCS , Milan , Italy.

Benign thyroid nodules are a common clinical occurrence and usually do not require treatment unless symptomatic. During the last years, ultrasound-guided minimally invasive treatments (MIT) gained an increasing role in the management of nodules causing local symptoms. In February 2018, the Italian MIT Thyroid Group was founded to create a permanent cooperation between Italian and international physicians dedicated to clinical research and assistance on MIT for thyroid nodules. Read More

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http://dx.doi.org/10.1080/02656736.2019.1575482DOI Listing
March 2019
1 Read

The Role of Ancillary Techniques in Salivary Gland Cytopathology Specimens.

Acta Cytol 2019 Mar 25:1-11. Epub 2019 Mar 25.

Department of Pathology, Emory University, Atlanta, Georgia, USA,

Salivary gland tumor aspiration cytology is a useful preoperative test to guide the most appropriate clinical and surgical management for these patients. Although salivary gland cytology is often useful to distinguish between non-neoplastic lesions, benign neoplasms and malignant neoplasms, there remain many challenges in this area. Specifically, these tumors are uncommon and may have considerable morphologic overlap, especially in the setting of a malignant tumor. Read More

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https://www.karger.com/Article/FullText/497109
Publisher Site
http://dx.doi.org/10.1159/000497109DOI Listing
March 2019
10 Reads

Trichofolliculoma of the Eyelid Margin: A Case Report and Review of Literature.

Ophthalmic Plast Reconstr Surg 2019 Mar 22. Epub 2019 Mar 22.

Kanupriya Dalmia Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, MTC Campus, Bhubaneswar, India.

Trichofolliculoma is a rare benign tumor of the skin, with distinct pilar differentiation and a predilection for the head and neck. To the best of the author's knowledge, only 10 cases of eyelid trichofolliculoma has been described in the English literature. Moreover, these benign hair follicle lesions have been reported to clinically mimic eyelid malignancy. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001363DOI Listing
March 2019
1 Read

Bilateral antrochoanal polyp: report of a new case and systematic review of the literature.

J Surg Case Rep 2019 Mar 20;2019(3):rjz074. Epub 2019 Mar 20.

Department of Otorhinolaryngology, Head and Neck Surgery, King Hassan II University & Ibn Rochd Hospital, Morocco.

Antrochonal polyp (ACP) is a benign, rare, and generally unilateral tumor which originates from the maxillary sinus mucosa. Bilateral ACP is extremely rare. Only few cases have been documented in the literature until 2018. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjz07
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http://dx.doi.org/10.1093/jscr/rjz074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425157PMC
March 2019
3 Reads

Comparative analysis of human papillomavirus type 6 complete genomes originated from head and neck and anogenital disorders.

Infect Genet Evol 2019 Mar 21;71:140-150. Epub 2019 Mar 21.

Department of Medical Microbiology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Nagyerdei krt. 98, Hungary. Electronic address:

It is increasingly recognized that fundamental differences exist between high-risk and low-risk human papillomavirus (HPV) genotypes regarding interactions with the host. This study aims to join the recently emerging efforts to uncover these differences at the complete genome level and to study how they may influence the disease caused. Sixteen samples of thirteen patients with various HPV6-mediated benign mucosal disorders (nine recurrent respiratory papillomatoses with 2-8 recurrences, one condyloma acuminatum and three premalignant lesions of the genital mucosa) were sampled to determine the complete virus genomes. Read More

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http://dx.doi.org/10.1016/j.meegid.2019.03.019DOI Listing
March 2019
1 Read

In-Office Laryngology Injections.

Otolaryngol Clin North Am 2019 Mar 21. Epub 2019 Mar 21.

Department of Otolaryngology-Head and Neck Surgery, Brooke Army Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam, Houston, TX 78234, USA.

The ability to perform in-office vocal fold injections has been greatly enhanced by advances in videolaryngoscopy technology. With improved optics and thin, channeled flexible laryngoscopes, in-office laryngeal injections have expanded from vocal fold augmentation for glottic insufficiency, vocal cold immobility, and botulinum toxin injections for spasmodic dysphonia, to vocal fold steroid injections for benign vocal fold lesions and scars and various injections for neurogenic cough. Efficacy, approaches, post-procedure management, and common complications of in-office laryngeal injections are outlined and supporting evidence discussed. Read More

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http://dx.doi.org/10.1016/j.otc.2019.02.006DOI Listing
March 2019
1 Read

Ultrasound-guided percutaneous laser ablation for papillary thyroid microcarcinoma: a retrospective analysis of 37 patients.

Cancer Imaging 2019 Mar 20;19(1):16. Epub 2019 Mar 20.

Department of Ultrasound, The Affiliated Suzhou Hospital of Nanjing Medical University, No. 1 Lijiang Road, Suzhou, 215163, China.

Background: Over the past ten years, more papillary thyroid microcarcinoma (PTMC) has been diagnosed more frequently due to the development of imaging technology, and the incidence of PTMC has increased significantly. Ultrasound-guided percutaneous laser ablation (PLA) is mainly used for benign thyroid nodules, and few studies have been published on the use of PLA for PTMC. In the present study, a retrospective analysis was performed to explore the efficacy of PLA for PTMC. Read More

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http://dx.doi.org/10.1186/s40644-019-0204-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425672PMC
March 2019
1 Read

Management of benign vocal fold lesions: current perspectives on the role for voice therapy.

Authors:
Anna White

Curr Opin Otolaryngol Head Neck Surg 2019 Mar 18. Epub 2019 Mar 18.

Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Purpose Of Review: Benign vocal fold lesions (BVFLs) cause dysphonia by preventing full vocal fold closure, interrupting vibratory characteristics and increasing compensatory muscle tension. Management includes phonosurgery, voice therapy, pharmacological treatment or more commonly a combination of these interventions. This review aims to present current perspectives on the management of BVFLs, particularly exploring the role of voice therapy. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000536DOI Listing
March 2019
2 Reads

Association between laryngopharyngeal reflux and benign vocal folds lesions: A systematic review.

Laryngoscope 2019 Mar 20. Epub 2019 Mar 20.

Laryngopharyngeal Reflux Study Group of the Young Otorhinolaryngologists of International Federation of Otorhinolaryngological Societies (YO-IFOS), Marseille, France.

Objectives: To investigate the role of laryngopharyngeal reflux (LPR) in the development of benign lesions of the vocal folds (BLVF).

Methods: PubMed, Cochrane Library, and Scopus were searched by three independent investigators for articles published between January 1990 and November 2018 providing substantial information about the role of LPR in the development of nodules, polyps, cysts, Reinke's edema, and sulcus vocalis. Inclusion, exclusion, diagnostic criteria and clinical outcome evaluation of included studies were analyzed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Read More

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http://dx.doi.org/10.1002/lary.27932DOI Listing
March 2019
1 Read

Benign Fibro-Osseous Lesions of the Head and Neck.

Head Neck Pathol 2019 Mar 18. Epub 2019 Mar 18.

Department of Radiology, Naval Medical Center San Diego, San Diego, CA, USA.

Benign fibro-osseous lesions (BFOLs) are a particularly challenging set of diagnoses for the pathologist. This diverse collection of diseases includes fibrous dysplasia, ossifying fibroma and cemento-osseous dysplasia. While all three conditions have similar microscopic presentations, their treatment and prognosis differ, demanding an accurate and definitive diagnosis. Read More

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http://dx.doi.org/10.1007/s12105-018-0992-5DOI Listing
March 2019
2 Reads

Clinical impact of a cytological screening system using cyclin D1 immunostaining and genomic analysis for the diagnosis of thyroid nodules.

BMC Cancer 2019 Mar 18;19(1):245. Epub 2019 Mar 18.

Department of Pathology, National Cancer Center Hospital, Tokyo, Japan.

Background: Fine-needle aspiration (FNA) is the most reliable method for diagnosing thyroid nodules; however, some features such as atypia of undetermined significance or follicular lesion of undetermined significance can confound efforts to identify malignancies. Similar to BRAF, cyclin D1 may be a strong marker of cell proliferation.

Methods: One hundred two patients with thyroidal nodule were enrolled in this prospective study. Read More

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http://dx.doi.org/10.1186/s12885-019-5452-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423761PMC
March 2019
1 Read

Promoter Hypomethylation as Recurrence Predictive Marker in Well-Differentiated Thyroid Carcinomas.

Int J Mol Sci 2019 Mar 16;20(6). Epub 2019 Mar 16.

Department of Clinical Genetics, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, 7100 Vejle, Denmark.

Despite the low mortality rates, well-differentiated thyroid carcinomas (WDTC) frequently relapse. and mutations have been extensively related to prognosis in thyroid cancer. In this study, the methylation levels of selected CpGs (5-cytosine-phosphate-guanine-3) comprising a classifier, previously reported by our group, were assessed in combination with and mutations. Read More

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http://dx.doi.org/10.3390/ijms20061334DOI Listing
March 2019
1 Read

Papillary hemangioma in the spinal canal of a patient with a germline 12p microdeletion.

Histopathology 2019 Mar 18. Epub 2019 Mar 18.

Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Spinal hemangiomas, though frequent in the vertebrae, are rare in the spinal canal with only slightly over 100 purely epidural cases reported to date, most of them classified as either cavernous or capillary hemangiomas . Papillary hemangiomas are rare tumors that were previously described as distinctive benign cutaneous lesions that appear as solitary bluish papules in the head and neck . We describe the first report of this neoplasm arising in the spinal canal and discuss the cytogenetic findings of this rare, possibly syndromic, disease entity. Read More

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http://dx.doi.org/10.1111/his.13861DOI Listing
March 2019
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A retrospective study of oral and maxillofacial pathology lesions diagnosed at the Faculty of Dentistry, King Abdulaziz University.

Clin Cosmet Investig Dent 2019 4;11:45-52. Epub 2019 Mar 4.

Oral Diagnostic Science Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia,

Background: Oral and maxillofacial lesions (OMFL) comprise a broad spectrum of benign and malignant lesions that affect the oral cavity. However, few epidemiological studies have evaluated oral cavity lesions, and very few have focused on oral soft tissue pathology. The purpose of this study was to identify the prevalence and distribution of OMFL that had been diagnosed histologically at the Oral Pathology Laboratory, Faculty of Dentistry, King Abdulaziz University. Read More

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http://dx.doi.org/10.2147/CCIDE.S190092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404671PMC
March 2019
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What every dentist needs to know about liquid biopsies.

Gen Dent 2019 Mar-Apr;67(2):31-33

Integral components of the examination of the oral and maxillofacial region include the early detection of benign and malignant lesions and recognition of manifestations of systemic disorders. The gold standard for establishing a diagnosis has entailed excision of tissue and submission to a laboratory for histopathologic review or, to a lesser extent, microcollection of cells via a fine-needle aspiration biopsy. A revolutionary technology in the medical and dental fields, referred to as a liquid biopsy, involves the harvesting of fragments of DNA or RNA for surveillance of an array of pathological processes from various body fluids, such as blood, plasma, and saliva. Read More

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March 2019
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CT features of parathyroid carcinomas: comparison with benign parathyroid lesions.

Jpn J Radiol 2019 May 12;37(5):380-389. Epub 2019 Mar 12.

Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima City, 890-8544, Japan.

Purpose: To describe CT features of parathyroid carcinomas (PCs) by comparison with benign parathyroid lesions (BPs).

Methods: This retrospective study comprised 82 patients with 76 BPs (62 adenomas and 14 hyperplastic lesions) and 6 PCs. CT features (size, short-to-long axis ratio, shape, peritumoral infiltration, homogeneity, calcification, attenuation values on unenhanced CT, and contrast enhancement during arterial and venous phases) were compared between PCs and BPs. Read More

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http://dx.doi.org/10.1007/s11604-019-00825-3DOI Listing
May 2019
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New Insights into the Role of Human Papillomavirus in Anal Cancer and Anal Wart Development.

Acta Cytol 2019 12;63(2):118-123. Epub 2019 Mar 12.

Faculty of Medicine of the University of Porto, Porto, Portugal,

Human papillomavirus is associated with several anogenital and oropharyngeal lesions, including warts, premalignant lesions, and cancer. There are specific groups that were identified as high-risk groups for anal squamous cell carcinoma and anal human papillomavirus infection, namely HIV-positive patients, men who have sex with men, women with genital tract neoplasia, and solid organ transplant recipients. Condylomas have classically been considered to be a benign lesion, with an exception made for the Buschke-Loewenstein tumor, but several publications have shown that a high percentage of condylomas harbor high-grade lesions. Read More

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http://dx.doi.org/10.1159/000491815DOI Listing
March 2019
6 Reads

Transoral endoscopic thyroidectomy using vestibular approach: A single center experience.

J Postgrad Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Surgery, Seth GS Medical College, Parel, Mumbai, Maharashtra, India.

Background: Thyroid Natural Orifice Transluminal Endoscopic Surgery (NOTES) or transoral endoscopic thyroidectomy using vestibular approach is a recent advance embraced by the surgical community because of its potential for a scar-free thyroidectomy. In this article, we present our initial experience with this technique.

Materials And Methods: We used a three-port technique through the oral vestibule, one 10 mm port for the laparoscope and two additional 5 mm ports for the endoscopic instruments required. Read More

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http://dx.doi.org/10.4103/jpgm.JPGM_117_18DOI Listing
March 2019
2 Reads

Diffusion weighted imaging of esthesioneuroblastoma: Differentiation from other sinonasal masses.

Head Neck 2019 May 7;41(5):1161-1164. Epub 2019 Mar 7.

Department of Radiology, University of California San Francisco, San Francisco, California.

Background: Differentiating esthesioneuroblastoma (ENB) from other sinonasal tumors is difficult by MRI. We tested whether diffusion weighted imaging (DWI) could distinguish ENB from other sinonasal tumors.

Methods: Hundred forty-six patients underwent sinonasal MRI, 75 with technically successful DWI. Read More

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http://dx.doi.org/10.1002/hed.25365DOI Listing
May 2019
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Glottic Carcinoma in Young Patients.

Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):25S-32S

3 Department of Surgery, Harvard Medical School, Boston, MA, USA.

Introduction:: Recent reported evidence indicates that vocal cord carcinoma is evolving similarly to oropharyngeal cancer with an increasing number of patients without a smoking history having human papillomavirus (HPV) disease. Observations also suggest that an increasing number of patients who present with glottic carcinoma are younger than has been reported in the past. Therefore, an investigation was done to examine the incidence of glottic carcinoma in patients 30 years old (y/o) or younger. Read More

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http://dx.doi.org/10.1177/0003489418818852DOI Listing
March 2019
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Evolution Strategies in Transaxillary Robotic Thyroidectomy: Considerations on the First 449 Cases Performed.

J Laparoendosc Adv Surg Tech A 2019 Apr 21;29(4):433-440. Epub 2019 Mar 21.

3 Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.

Background: In the past 20 years, the fast spread of new surgical technologies has reached an important peak with the advent of the robotic surgery. Many studies have been run about a cosmetic desire to avoid neck scars after thyroid surgery and this has led to the development of remote access robotic thyroidectomy (RT). Among the various RT approaches, unilateral transaxillary access is one of the most widely used, reporting excellent results in terms of feasibility and patient's compliance. Read More

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http://dx.doi.org/10.1089/lap.2019.0021DOI Listing
April 2019
4 Reads

Osteoarticular lesion in xanthoma disseminatum treated with total hip arthroplasty: a case report.

J Med Case Rep 2019 Mar 5;13(1):51. Epub 2019 Mar 5.

Department of Orthopaedics Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

Introduction: Xanthoma disseminatum is a very rare disease classified as a benign non-Langerhans cell histiocytosis, which is rarely associated with osteoarticular lesions. There is only a report of tumor abrasion during treatment of osteoarticular lesions of this disease, artificial joint replacement has not been reported. We describe a patient in whom bilateral total joint replacement was performed for disseminated xanthoma lesions of the hip joints. Read More

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http://dx.doi.org/10.1186/s13256-019-2005-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399818PMC
March 2019
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Comprehensive evaluation of medullary thyroid carcinoma before surgery.

Chin Med J (Engl) 2019 Apr;132(7):834-841

Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Background: Medullary thyroid carcinoma (MTC) is a rare disease, but it exhibits more aggressive behaviors. The aim of this study was to improve the diagnostic accuracy of MTC before surgery by analyzing the clinical and ultrasonic data of patients with MTC.

Methods: The study included 71 patients (96 lesions) with histopathologically proven MTC between April 2011 and September 2016 in the Cancer Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000160DOI Listing
April 2019
4 Reads

[Management of Cervical Spondylosis by Neurologists].

Authors:
Tetsuo Ando

Brain Nerve 2019 Mar;71(3):239-248

Department of Neurology, Anjo Kosei Hospital.

Neurologists have to manage patients with cervical spondylosis, a common neurological disease in individuals over the age of 50 years. The diagnosis of cervical spondylosis requires a detailed neurological examination that takes into account cervical levels. To prevent misdiagnosis, it is important to integrate the levels of the lesions revealed by imaging with the clinical findings. Read More

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http://dx.doi.org/10.11477/mf.1416201249DOI Listing
March 2019
7 Reads

A case report of a giant mature teratoma of the thyroid gland in a young girl.

Medicine (Baltimore) 2019 Mar;98(9):e14703

Rationale: Teratomas are extremely rare in the thyroid gland. A cervical teratoma presenting as a cystic or mixed thyroid lesion can be easily confused with a thyroglossal duct cyst. It is difficult for pediatricians to differentiate between these 2 types of lesions. Read More

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http://dx.doi.org/10.1097/MD.0000000000014703DOI Listing
March 2019
1 Read