10,842 results match your criteria Belgian Journal Of Zoology[Journal]


Vascular function and cardiovascular risk in a HIV infected and HIV free cohort of African ancestry: baseline profile, rationale and methods of the longitudinal EndoAfrica-NWU study.

BMC Infect Dis 2020 Jul 3;20(1):473. Epub 2020 Jul 3.

Centre for Cardiometabolic Research in Africa, Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa.

Background: People living with the Human Immunodeficiency Virus (PLHIV) have an increased susceptibility to develop non-communicable diseases such as cardiovascular disease (CVD). Infection with HIV contributes to the development of CVD independent of traditional risk factors, with endothelial dysfunction being the central physiological mechanism. While HIV-related mortality is declining due to antiretroviral treatment (ART), the number of deaths due to CVD is rising in South Africa - the country with the highest number of PLHIV and the world's largest ART programme. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-05173-6DOI Listing

An evaluation of managed entry agreements in Belgium: A system with threats and (high) potential if properly applied.

Health Policy 2020 Jun 18. Epub 2020 Jun 18.

Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium.

Objective: To evaluate the strengths and weaknesses of managed entry agreements (MEAs) in Belgium.

Methods: All Belgian MEAs signed between 2010 and 2015 (n = 71) were studied, including the re-evaluations of 16 reimbursement requests for which the initial MEA had ended. The analysis was supported by the findings from a systematic literature review and structured interviews with Belgian stakeholders. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healthpol.2020.06.007DOI Listing

Checklist of the fresh and brackish water snails (Mollusca, Gastropoda) of Bénin and adjacent West African ecoregions.

Zookeys 2020 18;942:21-64. Epub 2020 Jun 18.

Royal Belgian Institute of Natural Sciences (RBINS), Vautierstraat 29, B-1000, Brussels, Belgium.

Currently no comprehensive checklist of fresh and brackish water gastropods from Bénin exists, and those for adjacent West African areas are outdated. Yet, such checklists provide essential biodiversity information and a consistent taxonomic and nomenclatural framework for that biodiversity. Here a first checklist of the fresh and brackish water gastropods from Bénin and adjacent West African ecoregions is presented, based on an extensive literature review and field surveys between September 2014 and June 2019 in six major fresh and brackish water ecosystems in Bénin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3897/zookeys.942.52722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316818PMC

Radioisotopes demonstrate changes in global atmospheric circulation possibly caused by global warming.

Sci Rep 2020 Jul 1;10(1):10695. Epub 2020 Jul 1.

Indiana University Bloomington, Bloomington, Indiana, USA.

In this paper, we present a new method to study global atmospheric processes and their changes during the last decade. A cosmogenic radionuclide measured at ground-level, beryllium-7, is utilized as a proxy to study atmospheric dynamics. Beryllium-7 has two advantages: First, this radionuclide, primarily created in the lower stratosphere, attaches to aerosols that are transported downwards to the troposphere and travel around the globe with the general atmospheric circulation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-66541-5DOI Listing

BSGIE survey on COVID-19 and gastrointestinal endoscopy in Belgium : results and recommendations.

Acta Gastroenterol Belg 2020 Apr-Jun;83(2):344-354

Cliniques Universitaires Saint-Luc, Brussels.

Background And Aims: With the first wave of the COVID-19 pandemic declining, activities in the gastrointestinal clinic are being recommenced after a period of stringent measures. Since a second COVID-19 wave is not entirely ruled out health care professionals might remain faced with the need to perform endoscopic procedures in patients with a confirmed positive or unknown COVID-19 status. With this report we aim to provide a practical relevant overview of preparation and protective measures for gastroenterologists based on the currently available guidelines and our local experience and results of a national Belgian survey, to guarantee a fast recall of an adequate infection prevention if COVID-19 reoccurs. Read More

View Article

Download full-text PDF

Source

Liver transplantation during the COVID-19 epidemic : recommendations from the Belgian Liver Intestine Transplant Committee (BeLIAC).

Acta Gastroenterol Belg 2020 Apr-Jun;83(2):340-343

KUL Liver Transplant Program, Universitair Ziekenhuis Gasthuisberg, Leuven, Belgium.

Since January 2020, the Novel Coronavirus Disease 2019 (COVID-19) pandemic has dramatically impacted the world. In March 2020, the COVID-19 epidemic reached Belgium creating uncertainty towards all aspects of life. There has been an impressive capacity and solidarity of all healthcare professionals to acutely reconvert facilities to treat these patients. Read More

View Article

Download full-text PDF

Source

Use of cardiac telerehabilitation during COVID-19 pandemic in Belgium.

Acta Cardiol 2020 Jun 30:1-4. Epub 2020 Jun 30.

Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Limburg, Belgium.

The COVID-19 pandemic has forced many cardiac rehabilitation centres to focus more on the remote delivery of cardiac rehabilitation (CR) components. This increased focus and the lessons learned from this period could enhance the implementation of telerehabilitation and increase the participation in CR in Belgium. We conducted a survey between April and May 2020 about the implementation of telerehabilitation services during the COVID-19 pandemic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00015385.2020.1786625DOI Listing

de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia.

Acta Neuropathol Commun 2020 Jun 29;8(1):94. Epub 2020 Jun 29.

Laboratory of Histology, Neuroanatomy and Neuropathology, Faculty of Medicine, Université Libre de Bruxelles, ULB Neuroscience Institute, 808 route de Lennik, Bldg GE, B-1070, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-020-00977-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325098PMC

Genetic characterization of Shigatoxigenic and enteropathogenic Escherichia coli O80:H2 from diarrheic and septicemic calves and relatedness to human Shigatoxigenic E. coli O80:H2.

J Appl Microbiol 2020 Jun 29. Epub 2020 Jun 29.

Bacteriology, Department of Infectious Diseases, Faculty of Veterinary Medicine, Centre for Fundamental and Applied Research for Animals and Health (FARAH), University of Liège (ULiège), Belgium.

Aim: The purpose of this work was to identify and genetically characterize enterohemorrhagic E. coli (EHEC) and enteropathogenic E. coli (EPEC) O80:H2 from diarrheic and septicemic calves in Belgium and to comparing them with human EHEC after whole genome sequencing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jam.14759DOI Listing

Safety of endoscopic retrograde cholangiopancreatography in the pediatric population: a multicentre study.

Endoscopy 2020 Jun 29. Epub 2020 Jun 29.

Regional University Hospital of Nancy, Hepato-Gastroenterology Department, Vandoeuvre-les-Nancy, France.

Introduction: The aims of this retrospective multicentre study were to assess the technical success and adverse events of ERCP procedures in children in French and Belgian centres.

Methods: All children aged one day to seventeen years who underwent ERCP between January 2008 and March 2019 in 15 tertiary care hospitals were retrospectively included.

Results: 271 children underwent 470 ERCP procedures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-1209-0155DOI Listing

Prenatal particulate air pollution exposure and expression of the miR-17/92 cluster in cord blood: Findings from the ENVIRONAGE birth cohort.

Environ Int 2020 Jun 26;142:105860. Epub 2020 Jun 26.

Center for Environmental Sciences, Hasselt University, Hasselt, Belgium. Electronic address:

Background: Air pollution exposure during pregnancy is an important environmental health issue. Epigenetics mediate the effects of prenatal exposure and could increase disease predisposition in later life. The oncogenic miR-17/92 cluster is involved in normal development and disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envint.2020.105860DOI Listing

Predicting patient nurse-level intensity for a subsequent shift in the intensive care unit: A single-centre prospective observational study.

Int J Nurs Stud 2020 Jun 2;109:103657. Epub 2020 Jun 2.

Leuven Institute for Healthcare Policy, KU Leuven - University of Leuven, Kapucijnenvoer 35, 3000 Leuven; Belgium & Quality Improvement Department, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

Background: A dynamic optimized nurse staffing model for the Intensive Care Unit (ICU), requires a tool for monitoring nurse-level intensity with validated cut-offs to identify patients requiring 1:1, 2:1 or 3:1 patient-to-nurse ratios.

Objectives: We aimed to determine the Nursing Activities Score (NAS) cut-off values which can best distinguish between high, average and lower nurse-level intensity as unanimously perceived by care providers, and to evaluate whether these NAS cut-offs allow to predict nurse-level intensity in the next shift or the same shift the next day.

Design: A prospective observational study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijnurstu.2020.103657DOI Listing

Travel preparation and health risks in Dutch and Belgian medical students during an elective in low- or middle-income countries: A prospective self-reporting cohort study.

Travel Med Infect Dis 2020 Jun 23:101779. Epub 2020 Jun 23.

Department of Nephrology, Leiden University Medical Center (LUMC), Leiden, the Netherlands; Department of Internal Medicine, Haga Teaching Hospital, The Hague, the Netherlands.

Background: Medical schools offer students the opportunity to perform international electives. This study aimed to assess health risks among medical students, to tailor institutional guidelines.

Methods: Multicenter study at Dutch and Belgian universities, among medical students who visited low- or middle-income countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tmaid.2020.101779DOI Listing

Jules Bordet: immunologist, bacteriologist and Nobel Prize winner.

Authors:
Harold Ellis

Br J Hosp Med (Lond) 2020 Jun 1;81(6):1-2. Epub 2020 Jun 1.

School of Medical Education, King's College London, London, UK.

This year marks the 150th anniversary of the birth of Jules Jean Baptiste Vincent Bordet, to give him his full name, the Belgian immunologist and bacteriologist. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12968/hmed.2020.0110DOI Listing

Bite force and its relation to jaw shape in domestic dogs.

J Exp Biol 2020 Jun 25. Epub 2020 Jun 25.

Mécanismes Adaptatifs et Evolution (MECADEV), Muséum national d'Histoire naturelle, CNRS ; 55 rue Buffon 75005 Paris, France.

Previous studies based on two-dimensional methods have suggested that the great morphological variability of cranial shape in domestic dogs has impacted bite performance. Here we use a three-dimensional biomechanical model based on dissection data to estimate the bite force of 47 dogs of various breeds at several bite points and gape angles. bite forces for three Belgian Shepherd dogs were used to validate our model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jeb.224352DOI Listing

Genome Sequence of a Pathogenic Vibrio cholerae O1 El Tor Strain Defective for the Entire Pathogenicity Island 1, Isolated in Eastern Democratic Republic of the Congo.

Microbiol Resour Announc 2020 Jun 25;9(26). Epub 2020 Jun 25.

Center for Applied Molecular Technologies, Institute of Clinical and Experimental Research, Université Catholique de Louvain, Brussels, Belgium

We report here a complete genome sequence of a O1 El Tor (Inaba; sequence type 515 [ST515]) strain isolated from a cholera patient in North Kivu Province, Democratic Republic of the Congo (DRC), which showed a complete deletion (∼80 kb) of the pathogenicity island 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MRA.00454-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317100PMC

Copper Resistance Mediates Long-Term Survival of in Wet Contact With Metallic Copper.

Front Microbiol 2020 3;11:1208. Epub 2020 Jun 3.

Microbiology Unit, Interdisciplinary Biosciences, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.

Metallic copper to combat bacterial proliferation in drinking water systems is being investigated as an attractive alternative to existing strategies. A potential obstacle to this approach is the induction of metal resistance mechanisms in contaminating bacteria, that could severely impact inactivation efficacy. Thus far, the role of these resistance mechanisms has not been studied in conditions relevant to drinking water systems. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2020.01208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284064PMC

Oyster Care: An Innovative Palliative Approach towards SPMI Patients.

Front Psychiatry 2020 8;11:509. Epub 2020 Jun 8.

KU Leuven, Leuven, Belgium.

Oyster Care is the result of the search by caregivers in Flanders, Belgium, to develop quality care for patients with a Severe and Persistent Mental Illness (SPMI). This article offers a conceptual analysis of the Oyster Care model, based on experiences, analysis, and reflection of the authors, and on several examples. The starting point of the development of this new care model is the complex and difficult context of the care for SPMI patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fpsyt.2020.00509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294963PMC

Long-Term Ranibizumab Treatment in Neovascular Age-Related Macular Degeneration: A Belgian Subanalysis from the Global Real-World LUMINOUS Study.

Clin Ophthalmol 2020 2;14:1473-1481. Epub 2020 Jun 2.

Novartis Pharma, Vilvoorde, Belgium.

Purpose: To evaluate long-term, real-world treatment patterns and outcomes of ranibizumab 0.5 mg for neovascular age-related macular degeneration (nAMD) in a Belgian cohort.

Patients And Methods: This Belgian (BE) cohort of the 5-year global observational LUMINOUS study included 229 patients with nAMD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/OPTH.S242547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277576PMC

Fibroblast growth factor 23: a biomarker of fibrosis and prognosis in heart failure with preserved ejection fraction.

ESC Heart Fail 2020 Jun 24. Epub 2020 Jun 24.

Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St. Luc, Avenue Hippocrate, 10, Brussels, 1200, Belgium.

Aims: Besides regulating calcium-phosphate metabolism, fibroblast growth factor 23 (FGF-23) has been associated with incident heart failure (HF) and left ventricular hypertrophy. However, data about FGF-23 in HF and preserved ejection fraction (HFpEF) remain limited. The aim of this study was to assess the association between FGF-23 levels, clinical and imaging characteristics, particularly diffuse myocardial fibrosis, and prognosis in HFpEF patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ehf2.12816DOI Listing

Medical assistance in dying and older persons in Belgium: trends, emerging issues and challenges.

Age Ageing 2020 Jun 22. Epub 2020 Jun 22.

Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.

In 2002, the Belgian Act on euthanasia came into effect, regulating the intentional ending of life by a physician at the patient's explicit request. Subsequently, the number of reported euthanasia deaths increased every year. Specifically, the proportion of euthanasia deaths in older persons has risen significantly in the last few years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ageing/afaa116DOI Listing

Prediction modelling studies for medical usage rates in mass gatherings: A systematic review.

PLoS One 2020 23;15(6):e0234977. Epub 2020 Jun 23.

Department of Public Health and Primary Care, Faculty of Medicine, KU Leuven, Leuven, Belgium.

Background: Mass gathering manifestations attended by large crowds are an increasingly common feature of society. In parallel, an increased number of studies have been conducted that developed and/or validated a model to predict medical usage rates at these manifestations.

Aims: To conduct a systematic review to screen, analyse and critically appraise those studies that developed or validated a multivariable statistical model to predict medical usage rates at mass gatherings. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234977PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310685PMC

The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries.

PLoS One 2020 23;15(6):e0234765. Epub 2020 Jun 23.

Leeds Institute for Medical Research, University of Leeds, Leeds, United Kingdom.

Background: To limit the spread of SARS-CoV-2, an evidence-based understanding of the symptoms is critical to inform guidelines for quarantining and testing. The most common features are purported to be fever and a new persistent cough, although the global prevalence of these symptoms remains unclear. The aim of this systematic review is to determine the prevalence of symptoms associated with COVID-19 worldwide. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234765PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310678PMC

Comparison of the disease activity score and the revised EUSTAR activity index in diffuse cutaneous systemic sclerosis patients.

Clin Exp Rheumatol 2020 Jun 15. Epub 2020 Jun 15.

Department of Rheumatology, Cliniques Universitaires Saint-Luc, Pôle de Pathologies Rhumatismales Inflammatoires et Systémiques, Université Catholique de Louvain, Brussels, Belgium.

Objectives: To compare the ability of the Disease Activity Score (DAS) and the Revised EUSTAR Activity Index (RAI) to detect diffuse cutaneous systemic sclerosis (dcSSc) patients requiring treatment intensification in a Belgian cohort.

Methods: We retrospectively compared the widely used DAS and the recently developed RAI in a longitudinal cohort (median follow-up of 42 months) of 62 dcSSc patients, of whom 30 with a disease duration ≤3 years at inclusion. Active disease was defined by a DAS ≥3/10 or a RAI ≥2. Read More

View Article

Download full-text PDF

Source

Satellite evidence for changes in the NO weekly cycle over large cities.

Sci Rep 2020 Jun 22;10(1):10066. Epub 2020 Jun 22.

Royal Netherlands Meteorological Institute, Satellite Observations, De Bilt, The Netherlands.

Anthropogenic activities, by far the largest source of NOx into the atmosphere, induce a weekly cycle of NO abundances in cities. Comprehensive analysis of the 2005-2017 OMI NO dataset reveals significant weekly cycles in 115 of the 274 cities considered. These results are corroborated by a full year of high-resolution TROPOMI NO observations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-66891-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308373PMC

A Stroll Along the Erroneous ePrescription Interactions Within the Belgian Pharmacy.

Stud Health Technol Inform 2020 Jun;270:803-807

Department of Public Health (GEWE), Vrije Universiteit Brussel, Belgium.

After the national introduction of the ePrescription in Belgium to the broader public in 2014, community pharmacists are still not satisfied completely. Reasons are (1) low acceptance of the implementation due to slow systems, (2) high reported downtimes, and (3) alert fatigue due to technical and incomprehensible error messages. Therefore, we investigated which technical errors occur in the flow of handling an ePrescription and how these errors can be avoided. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/SHTI200272DOI Listing

Levels of the Hemoglobin Adduct N-(2,3-Dihydroxypropyl)-valine in Cord and Maternal Blood: Prenatal Transfer of Glycidol in the ENVIRONAGE Birth Cohort.

Toxicol Lett 2020 Jun 19. Epub 2020 Jun 19.

Centre for Environmental Sciences, Hasselt University, Hasselt, Belgium. Electronic address:

Background: Glycidol, a probable human carcinogen, is a reactive chemical released in the gastrointestinal tract from glycidyl fatty acid esters, which are heat-induced dietary contaminants.

Objectives: To investigate the prenatal transfer of glycidol, a specific hemoglobin adduct was measured as a biomarker for internal glycidol exposure in paired cord and maternal blood samples.

Methods: In 100 mother-newborn pairs from the Belgian ENVIRONAGE (ENVIRonmental influence ON AGEing in early life) birth cohort, we studied the correlation between levels of the glycidol-derived hemoglobin adduct N-(2,3-dihydroxypropyl)-valine (2,3-diHOPr-Val) in paired cord and maternal blood samples. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxlet.2020.06.013DOI Listing

Data from the ERA-EDTA Registry was examined for trends in excess mortality in European adults on kidney replacement therapy.

Kidney Int 2020 Jun 19. Epub 2020 Jun 19.

ERA-EDTA Registry, Department of Medical Informatics, Amsterdam UMC, Academic Medical Center, Amsterdam Public Health Research Institute, University of Amsterdam, Amsterdam, the Netherlands.

The objective of this study was to investigate whether the improvement in survival seen in patients on kidney replacement therapy reflects the enhanced survival of the general population. Patient and general population statistics were obtained from the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry and the World Health Organization databases, respectively. Relative survival models were composed to examine trends over time in all-cause and cause-specific excess mortality, stratified by age and modality of kidney replacement therapy, and adjusted for sex, primary kidney disease and country. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.kint.2020.05.039DOI Listing

Patient-centered care coordination, education and counseling of patients treated with oral anticancer drugs: An importance-performance analysis.

Eur J Oncol Nurs 2020 May 4;47:101765. Epub 2020 May 4.

KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Clinical Pharmacology and Pharmacotherapy, Leuven, Belgium.

Purpose: To analyse the importance and performance of key elements in patient-centered care coordination, education and counseling of patients treated with oral anticancer drugs.

Method: In four Belgian non-academic hospitals, the importance and performance of a set of 82 key elements was cross-sectionally evaluated by primary and secondary healthcare professionals and by patients. These key elements were divided in 6 themes: coordination of care, style and content of patient contacts, medication counseling at treatment initiation, follow-up of treatment, psychosocial support, and involvement of family and friends. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejon.2020.101765DOI Listing

Model informed dosing of Hydroxycholoroquine in COVID-19 patients: Learnings from the recent experience, remaining uncertainties and Gaps.

Br J Clin Pharmacol 2020 Jun 19. Epub 2020 Jun 19.

Belgian Federal Agency for Medicines and Health Products, Brussels, Belgium.

Aims: In the absence of a commonly agreed dosing protocol based on pharmacokinetic considerations, the dose and treatment duration for hydroxychloroquine (HCQ) COVID-19 disease currently vary across national guidelines and clinical study protocols. We have used a model-based approach to explore the relative impact of alternative dosing regimens proposed in different dosing protocols for hydroxychloroquine in COVID-19.

Methods: We compared different PK exposures using Monte Carlo simulations based on a previously published population pharmacokinetic model in patients with rheumatoid arthritis, externally validated using both independent data in lupus erythematous patients and recent data in French COVID-19 patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bcp.14436DOI Listing

The added value of geriatric assessment in evaluating a patient's Health-Related Quality-of-Life: A study in ≥70-year-old early-stage invasive breast cancer patients.

Eur J Cancer Care (Engl) 2020 Jun 18:e13278. Epub 2020 Jun 18.

Laboratory of Experimental Oncology (LEO), Department of Oncology, KU Leuven, Leuven, Belgium.

Objective: The objective of this study was to assess the relationship between geriatric assessment (GA) and health-related Quality-of-Life (HRQOL) in older patients with breast cancer.

Methods: Patients were assigned either to adjuvant chemotherapy (CTG) or to a control group (CG). Spearman rank coefficients (ρ) calculated correlations between HRQOL and GA at baseline, 3 months and 1 year. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ecc.13278DOI Listing

Up to 5-year retention of abatacept in Belgian patients with moderate-to-severe rheumatoid arthritis: a sub-analysis of the international, observational ACTION study.

Rheumatol Int 2020 Jun 17. Epub 2020 Jun 17.

CHU Sart Tilman, Liège, Belgium.

Favorable efficacy and safety profiles have been demonstrated for abatacept in patients with rheumatoid arthritis (RA) in randomized controlled trials, but these data require validation during long-term follow-ups in routine clinical practice. This study explored long-term safety and retention rates in RA patients treated with intravenous abatacept in the Belgian cohort of the international AbataCepT In rOutiNe clinical practice (ACTION) study (NCT02109666). This non-interventional, observational, longitudinal study included Belgian patients aged ≥ 18 years with moderate-to-severe RA who started intravenous abatacept treatment as first- or second/further-line biologic therapy in routine clinical practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00296-020-04619-zDOI Listing

Detection of the 'systemic sentinel lymph node' in colorectal cancer using fluorescence imaging after indocyanine green intravenous injection: A feasibility study.

JMIR Res Protoc 2020 Jun 15. Epub 2020 Jun 15.

Institut Jules Bordet, Belgian Comprehensive Cancer Center, Université Libre de Bruxelles (ULB), BE 0257.981.101., Rue H. Bordet, 1, Brussels, BE.

Background: Nodal staging is a major concern in colorectal cancer (CRC) as it is an important prognostic factor. Several techniques have been developed to increase the accuracy of nodal staging that could potentially improve patient treatment and prognosis. Sentinel lymph node (SLN) detection has been shown to accurately reflect nodal status in various tumors and has become the standard procedure in nodal staging of breast cancer and melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2196/17976DOI Listing

Barriers and facilitators to participate in the colorectal cancer screening programme in Flanders (Belgium): a focus group study.

Acta Clin Belg 2020 Jun 18:1-8. Epub 2020 Jun 18.

Faculty of Medicine and Health Sciences, Department of Public Health and Primary Care, Ghent University , Ghent, Belgium.

Objective: In Flanders (Belgium), a population-based colorectal cancer (CRC) screening programme offers a faecal immunochemical test (FIT) biennially to Flemish citizens aged 50-74 years. A FIT uptake of only 51,5% in 2018 is significantly lower among men, lower income groups and among people with other than the Belgian nationality. The objective of this study was to identify attitudes, barriers and facilitators to participate in the Flemish CRC screening programme. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17843286.2020.1783906DOI Listing

The role of body image in sexual satisfaction among partnered older adults: a population-based study in four European countries.

Eur J Ageing 2020 Jun 6;17(2):163-173. Epub 2019 Nov 6.

University of Zagreb, Zagreb, Croatia.

Body image issues can affect all domains of sexual functioning. The aim of this study was to examine how, in a sociocultural context where physical and sexual attractiveness is equated with young and slim body ideals, appearance dissatisfaction and importance are related to sexual satisfaction in older adults in four European countries. A cross-sectional survey with probability samples of the population aged 60-75 years was used. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10433-019-00542-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292835PMC

Key Word Signing Has Higher Iconicity Than Sign Language.

J Speech Lang Hear Res 2020 Jun 16:1-7. Epub 2020 Jun 16.

Department of Neurosciences, Experimental Otorinolaryngology, KU Leuven, Belgium.

Purpose Key word signing (KWS) entails using manual signs to support the natural speech of individuals with normal hearing and who have communication difficulties. While manual signs from the local sign language may be used for this purpose, some KWS systems have opted for a distinct KWS lexicon. Distinct KWS lexicon typically aims for higher sign iconicity or recognizability to make the lexicon more accessible for individuals with intellectual disabilities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1044/2020_JSLHR-20-00034DOI Listing

Influence of Micro-Pore Connectivity and Micro-Fractures on Calcium Leaching of Cement Pastes-A Coupled Simulation Approach.

Materials (Basel) 2020 Jun 13;13(12). Epub 2020 Jun 13.

Institute of Construction and Building Materials, Technical University of Darmstadt, Franziska-Braun-Str 7, 64287 Darmstadt, Germany.

A coupled numerical approach is used to evaluate the influence of pore connectivity and microcracks on leaching kinetics in fully saturated cement paste. The unique advantage of the numerical model is the ability to construct and evaluate a material with controlled properties, which is very difficult under experimental conditions. Our analysis is based on two virtual microstructures, which are different in terms of pore connectivity but the same in terms of porosity and the amount of solid phases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma13122697DOI Listing

How to Communicate Food Safety after Radiological Contamination: The Effectiveness of Numerical and Narrative News Messages.

Int J Environ Res Public Health 2020 Jun 12;17(12). Epub 2020 Jun 12.

Department of Political Science, University of Antwerp, 2000 Antwerp, Belgium.

Food risk and the safety of foodstuffs in the aftermath of contamination are highly sensitive issues to communicate. Food risks receive extensive attention from the news media, which requires messages to be carefully drafted to minimize harm and avoid unnecessary boycotts. Once a food risk is deemed eliminated, communication efforts must rebuild trust among consumers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph17124189DOI Listing

Fibrinogen Increases Resveratrol Solubility and Prevents it from Oxidation.

Foods 2020 Jun 12;9(6). Epub 2020 Jun 12.

Center of Excellence for Molecular Food Sciences & Department of Biochemistry, Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia.

The French paradox describes a lower incidence of cardiovascular problems despite a high intake of saturated fats. This phenomenon was associated with higher consumption of red wine, as it was later discovered that the presence of antioxidants, including resveratrol, have beneficial effects. We hypothesized that resveratrol may have a more direct role in protection from harmful oxidation, presumably through binding to important proteins of the blood coagulation process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/foods9060780DOI Listing

Associations of barn air quality parameters with ultrasonographic lung lesions, airway inflammation and infection in group-housed calves.

Prev Vet Med 2020 Jun 9;181:105056. Epub 2020 Jun 9.

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.

Barn climate is believed to play a major role in the bovine respiratory disease complex. However, the exact air quality parameters associated with (sub)clinical pneumonia or airway inflammation in calves are currently unknown. The objective of this cross-sectional study was to assess associations of air quality parameters with clinical signs, lung consolidation, pulmonary inflammation and infection in group-housed calves. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prevetmed.2020.105056DOI Listing

Safety use of hydroxychloroquine and its combination with azithromycin in the context of Sars-CoV-2 outbreak: Clinical experience in a Belgian tertiary center.

Travel Med Infect Dis 2020 Jun 12:101788. Epub 2020 Jun 12.

Department of Internal Medicine and Infectious Diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tmaid.2020.101788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290202PMC

A genoserotyping system for a fast and objective identification of Salmonella serotypes commonly isolated from poultry and pork food sectors in Belgium.

Food Microbiol 2020 Oct 27;91:103534. Epub 2020 Apr 27.

Sciensano, Transversal Activities in Applied Genomics, B-1050, Brussels, Belgium.

Humans are mostly contaminated by Salmonella through the consumption of pork- and poultry-derived food products. Therefore, a strict monitoring of Salmonella serotypes in food-producing animals is needed to limit the transmission of the pathogen to humans. Additionally, Salmonella can lead to economic loss in the food sector. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fm.2020.103534DOI Listing
October 2020

Large-bodied sabre-toothed anchovies reveal unanticipated ecological diversity in early Palaeogene teleosts.

R Soc Open Sci 2020 May 13;7(5):192260. Epub 2020 May 13.

Department of Earth and Environmental Sciences, University of Michigan, Ann Arbor, MI, USA.

Many modern groups of marine fishes first appear in the fossil record during the early Palaeogene (66-40 Ma), including iconic predatory lineages of spiny-rayed fishes that appear to have originated in response to ecological roles left empty after the Cretaceous/Palaeogene extinction. The hypothesis of extinction-mediated ecological release likewise predicts that other fish groups have adopted novel predatory ecologies. Here, we report remarkable trophic innovation in early Palaeogene clupeiforms (herrings and allies), a group whose modern representatives are generally small-bodied planktivores. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rsos.192260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277248PMC

Real-life effectiveness and short-term (16-week) tolerance of guselkumab for psoriasis: a Belgian retrospective multicentre study.

J Eur Acad Dermatol Venereol 2020 Jun 14. Epub 2020 Jun 14.

Department of Dermatology, CHU-Centre-Ville, University of Liège, Liège, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdv.16715DOI Listing

Prevalence and Predictors of Sexual Difficulties and Associated Distress Among Partnered, Sexually Active Older Women in Norway, Denmark, Belgium, and Portugal.

Arch Sex Behav 2020 Jun 12. Epub 2020 Jun 12.

Department of Psychology, University of Oslo, Oslo, Norway.

There has been little comparative, cross-cultural research on sexual difficulties and associated distress, and factors associated with these, among older women. Therefore, the aim of this study was to investigate prevalence rates of sexual difficulties, distress related to these difficulties, and associated sociodemographic, relational, and health factors, among sexually active older women (60-75 years) in committed relationships across four European countries (Norway, Denmark, Belgium, and Portugal). These data could inform us about what differentiates women who do and do not experience distressing sexual difficulties and facilitate the identification of older women who might benefit from clinical interventions as well as the development of new interventions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10508-020-01742-7DOI Listing

Development of a flowchart reflecting the current attitude and approach towards idiopathic overactive bladder treatment in Belgium: A Delphi study.

Neurourol Urodyn 2020 Jun 12. Epub 2020 Jun 12.

Department of Urology, Ghent University Hospital, Ghent University, Ghent, Belgium.

Aims: Idiopathic overactive bladder syndrome (iOAB) is a prevalent condition in urological practice. The variability in management between specialists and between centers remains high. Even existing guidelines contain inconsistencies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/nau.24421DOI Listing

Programmed intermittent epidural bolus vs. patient-controlled epidural analgesia for maintenance of labour analgesia: a two-centre, double-blind, randomised study.

Anaesthesia 2020 Jun 12. Epub 2020 Jun 12.

Department of Cardiovascular Sciences, KU Leuven, Belgium.

The programmed intermittent epidural bolus technique has shown superiority to continuous epidural infusion techniques, with or without patient-controlled epidural analgesia for pain relief, reduced motor block and patient satisfaction. Many institutions still use patient-controlled epidural analgesia without a background infusion, and a comparative study between programmed intermittent epidural bolus and patient-controlled epidural analgesia without a background infusion has not yet been performed. We performed a randomised, two-centre, double-blind, controlled trial of these two techniques. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/anae.15149DOI Listing
June 2020
3.382 Impact Factor

Carbon isotopic characterization of prednisolone and prednisone pharmaceutical formulations: Implications in antidoping analysis.

Drug Test Anal 2020 Jun 11. Epub 2020 Jun 11.

Laboratorio Antidoping, Federazione Medico Sportiva Italiana, Rome, Italy.

Twenty-two pharmaceutical formulations containing prednisolone or prednisone commercially available in Italy, Belgium, Spain, Brazil, and India were analyzed through a specific gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) method. All of them showed typical non-endogenous δ C values, except for the Belgian nasal spray, Sofrasolone®, with a less depleted C content (-17.84 ± 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dta.2876DOI Listing

The WetNet: What the Oral Polio Vaccine Hypothesis Exposes about Globalized Interspecies Fluid Bonds.

Authors:
S Lochlann Jain

Med Anthropol Q 2020 Jun 12. Epub 2020 Jun 12.

Department of Anthropology, Stanford University.

The author analyzes the aftermath of Edward Hooper's suggestion that the trial of an oral polio vaccine (OPV) in the Belgian colonies of Africa engendered the pandemic form of the AIDS virus, HIV-1. In response to Hooper's book, The River (1999), the Royal Society in London held a conference to debate the origins of HIV. Examination of the quick dismissal of the OPV theory opens a space for legitimately challenging the widely held belief that the vaccine contamination question was convincingly resolved. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/maq.12587DOI Listing