1,086 results match your criteria Behavioural Neurology[Journal]


Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors.

Behav Neurol 2020 7;2020:4813616. Epub 2020 Jun 7.

Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Methods: Mouse neonates were exposed to MS paradigm 3 hours daily from postnatal days (PND) 2 to 14. The control and MS mice were divided separately into 16 groups ( = 8) (8 groups for each set) including mice that received normal saline, mice that received rutin at doses of 10, 50, and 100 mg/kg, mice that received NMDA at a dose of 150 mg/kg, mice that received ketamine (NMDA antagonist) at a dose of 0.25 mg/kg, mice that received NMDA antagonist plus a subeffective dose of rutin, and mice that received NMDA plus an effective dose of rutin. Read More

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http://dx.doi.org/10.1155/2020/4813616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296444PMC

Factors Associated with Anxiety and Depression among Diabetes, Hypertension, and Heart Failure Patients at Dessie Referral Hospital, Northeast Ethiopia.

Behav Neurol 2020 16;2020:3609873. Epub 2020 May 16.

Department of Nursing, School of Nursing and Midwifery, Wollo University, Dessie, Ethiopia.

Background: Anxiety and depression are common in patients with diabetes, hypertension, and heart failure. However, they are usually unrecognized and untreated especially in developing countries. Identifying factors associated with anxiety and depression is helpful for early screening and management. Read More

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http://dx.doi.org/10.1155/2020/3609873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246401PMC

A Novel PRRT2 Variant in Chinese Patients Suffering from Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsion.

Behav Neurol 2020 18;2020:2097059. Epub 2020 May 18.

Department of Biology, School of Basic Medicine, Jiamusi University, Jiamusi City, Heilongjiang Province, 154007, China.

PRRT2 mutations are the major causative agent of paroxysmal kinesigenic dyskinesia with infantile convulsion (PKD/IC). The study is aimed at screening PRRT2 gene mutations in patients who suffered from PKD/IC in Chinese population. Thirteen Chinese patients with PKD/IC were screened randomly for coding exons of the PRRT2 gene mutation along with 50 ethnically coordinated control people. Read More

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http://dx.doi.org/10.1155/2020/2097059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251426PMC

Word Processing Is Faster than Picture Processing in Alzheimer's Disease.

Behav Neurol 2020 25;2020:9541869. Epub 2020 Jan 25.

Geriatric Behavioral Neurology Project, Tohoku University New Industry Hatchery Center (NICHe), 4-1, Seiryo-machi, Aoba-ku, IDAC, 980-8575 Sendai, Japan.

Objective: Alzheimer's disease (AD) is characterized by a slow progressive impairment of episodic memory. Many studies have shown that AD exhibits deterioration of semantic memory during the course of disease progression. We previously reported that AD patients exhibited severe access disorders in the semantic memory system, using the Momentary Presentation Task (20 or 300 ms). Read More

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http://dx.doi.org/10.1155/2020/9541869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204340PMC
January 2020

Small Fiber Neuropathy: Clinicopathological Correlations.

Behav Neurol 2020 2;2020:8796519. Epub 2020 Jan 2.

Department of Neurology, University of Pécs, Medical School, Pécs, Hungary.

Small fiber neuropathy develops due to the selective damage of the thin fibers of peripheral nerves. Many common diseases can cause this condition, including diabetes, infections, autoimmune and endocrine disorders, but it can occur due to genetic alterations, as well. Eighty-five skin biopsy-proven small-fiber neuropathy cases were analyzed. Read More

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http://dx.doi.org/10.1155/2020/8796519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199601PMC
January 2020

Social Cognition in Rehabilitation Context: Different Evolution of Affective and Cognitive Theory of Mind in Mild Cognitive Impairment.

Behav Neurol 2020 4;2020:5204927. Epub 2020 Jan 4.

Department of Human and Social Science, Università degli Studi di Bergamo, Bergamo, Italy.

Maintaining social skills such as Theory of Mind (ToM) competences is important to counteract the conversion into dementia in Mild Cognitive Impairment (MCI). Multidimensional nonpharmacological interventions demonstrated their potential in improving cognitive and behavioral abilities; however, little is known about the long-term effect of such interventions on social skills in people with MCI. The aim of this longitudinal study was to monitor ToM competences considering both cognitive and affective domains in an amnestic MCI (aMCI) sample involved in a home-based multistimulation treatment (MST@H). Read More

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http://dx.doi.org/10.1155/2020/5204927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199603PMC
January 2020

Neuropsychological Changes in Complex Regional Pain Syndrome (CRPS).

Behav Neurol 2020 14;2020:4561831. Epub 2020 Jan 14.

Centre for Pain Research, University of Bath, Claverton Down Road, Bath BA2 7AY, UK.

Complex Regional Pain Syndrome (CRPS) is a poorly understood chronic pain condition of multifactorial origin. CRPS involves sensory, motor, and autonomic symptoms primarily affecting one extremity. Patients can also present with neuropsychological changes such as reduced attention to the CRPS-affected extremity, reminiscent of hemispatial neglect, yet in the absence of any brain lesions. Read More

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http://dx.doi.org/10.1155/2020/4561831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201816PMC
January 2020

Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study.

Behav Neurol 2020 2;2020:6250524. Epub 2020 Jan 2.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taiwan.

Background: Action observation therapy and mirror therapy, two promising rehabilitation strategies, are aimed at enhancing the motor learning and functional improvement of stroke patients through different patterns of visual feedback and observation.

Objective: This study investigated and compared the treatment effects of the action observation therapy, mirror therapy, and active control intervention on motor and functional outcomes of stroke patients.

Methods: Twenty-one patients with subacute stroke were recruited in this study. Read More

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http://dx.doi.org/10.1155/2020/6250524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199557PMC
January 2020

"Olfactory Three-Needle" Enhances Spatial Learning and Memory Ability in SAMP8 Mice.

Behav Neurol 2020 2;2020:2893289. Epub 2020 Jan 2.

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.

As one of the most important therapies in complementary and alternative medicine, acupuncture has been used in the treatment of Alzheimer's disease (AD). Acupuncture of "olfactory three-needle" manipulation can improve the cognitive ability of AD patients. However, the mechanism of "olfactory three-needle" in AD remains largely unknown. Read More

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http://dx.doi.org/10.1155/2020/2893289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199563PMC
January 2020

Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia.

Behav Neurol 2020 14;2020:4683573. Epub 2020 Apr 14.

Faculty of Psychology, University of Salamanca, Salamanca, Spain.

This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer's disease are also present during the disorder's preclinical stages. Read More

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http://dx.doi.org/10.1155/2020/4683573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178534PMC

Primary Cognitive Factors Impaired after Glioma Surgery and Associated Brain Regions.

Behav Neurol 2020 25;2020:7941689. Epub 2020 Mar 25.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan.

Previous studies have shown that cognitive impairments in patients with brain tumors are not severe. However, to preserve the postsurgical QOL of patients with brain tumors, it is important to identify "primary" cognitive functions and associated brain regions that are more vulnerable to cognitive impairments following surgery. The objective of this study was to investigate primary cognitive factors affecting not only simple cognitive tasks but also several other cognitive tasks and associated brain regions. Read More

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http://dx.doi.org/10.1155/2020/7941689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132357PMC

Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review.

Behav Neurol 2020 25;2020:2536319. Epub 2020 Mar 25.

Department of Neurosurgery, University Hospital of Basel, Basel, Switzerland.

In recent years, neuroendoscopic treatment of hydrocephalus and various ventricular pathologies has become increasingly popular. It is considered by many as the first-choice treatment for the majority of these cases. However, neurocognitive complications following ventricular neuroendoscopic procedures may occur leading mostly to amnesia, which might have a grave effect on the patient's quality of life. Read More

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http://dx.doi.org/10.1155/2020/2536319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132360PMC

Chronic Pain Hurts the Brain: The Pain Physician's Perspective.

Behav Neurol 2020 21;2020:3786562. Epub 2020 Mar 21.

Somogy County Kaposi Mór Teaching Hospital, Kaposvár, Hungary.

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http://dx.doi.org/10.1155/2020/3786562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115041PMC

Too Real to Be Virtual: Autonomic and EEG Responses to Extreme Stress Scenarios in Virtual Reality.

Behav Neurol 2020 12;2020:5758038. Epub 2020 Mar 12.

Far Eastern Regional Scientific Centre of the Russian Academy of Education, Vladivostok, Russia.

The evolution of virtual reality (VR) technologies requires setting boundaries of its use. In this study, 3 female participants were experiencing VR scenarios with stressful content and their activity of the autonomic nervous system and EEG were recorded. It has been discovered that virtual reality can evoke acute stress reactions accompanied by activation of the sympathetic nervous system and a decrease in the activity of the parasympathetic nervous system. Read More

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http://dx.doi.org/10.1155/2020/5758038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091527PMC

Changes in Physiological and Pathological Behaviours Produced by Deep Microelectrode Implantation Surgery in Rats: A Temporal Analysis.

Behav Neurol 2020 9;2020:4385706. Epub 2020 Mar 9.

Laboratory of Neurophysiology, Department of Cellular and Molecular Biology, CUCBA, University of Guadalajara, Mexico.

Physiological behaviours such as the sleep-wake cycle and exploratory behaviours are important parameters in intact and sham-operated animals and are usually thought to be unaffected by experimental protocols in which neurosurgery is performed. However, there is insufficient evidence in the literature on the behavioural and cognitive effects observed after deep microelectrode implantation surgery in animal models of neurological diseases. Similarly, in studies that utilize animal models of neurological diseases, the impact of surgery on the pathological phenomena being studied is often minimized. Read More

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http://dx.doi.org/10.1155/2020/4385706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085361PMC

Maternal Separation Early in Life Alters the Expression of Genes and in Adult Female Mice: Correlation with Social Behavior.

Behav Neurol 2020 3;2020:7830469. Epub 2020 Mar 3.

Laboratory of Gene Expression Regulation, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russia.

Early-life stress affects neuronal plasticity of the brain regions participating in the implementation of social behavior. Our previous studies have shown that brief and prolonged separation of pups from their mothers leads to enhanced social behavior in adult female mice. The goal of the present study was to characterize the expression of genes (which are engaged in synaptic plasticity) , , , and in the prefrontal cortex and dorsal hippocampus of adult female mice with a history of early-life stress. Read More

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http://dx.doi.org/10.1155/2020/7830469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072106PMC

Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats.

Behav Neurol 2020 20;2020:9370891. Epub 2020 Feb 20.

Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China.

Objective: Propofol is a classical anesthetic and induces consciousness loss, and gamma-aminobutyric-acid-type-A (GABA-A) receptor is its target. Righting reflex is associated with conscious response. The nucleus basalis (NB) acts as a major relay between the reticular activating system and the frontal cortex (FC). Read More

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http://dx.doi.org/10.1155/2020/9370891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053451PMC
February 2020

False Memory in Alzheimer's Disease.

Behav Neurol 2020 19;2020:5284504. Epub 2020 Feb 19.

Unité de Gériatrie, Centre Hospitalier de Tourcoing, Tourcoing, France.

Patients with Alzheimer's Disease (AD) not only are suffering from amnesia but also are prone to memory distortions, such as experiencing detailed and vivid recollections of episodic events that have never been encountered (i.e., false memories). Read More

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http://dx.doi.org/10.1155/2020/5284504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049840PMC
February 2020

Personality Factors and Subjective Cognitive Decline: The FACEHBI Cohort.

Behav Neurol 2020 19;2020:5232184. Epub 2020 Feb 19.

Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.

Individuals with subjective cognitive decline (SCD) have the perception of memory problems without showing impairment on standardized cognitive tests. SCD has been associated with an increased risk of developing Alzheimer's disease (AD). Neuroticism and openness personality dimensions have also been associated with SCD and AD. Read More

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http://dx.doi.org/10.1155/2020/5232184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049847PMC
February 2020

Potential Benefits of Physical Activity in MCI and Dementia.

Behav Neurol 2020 12;2020:7807856. Epub 2020 Feb 12.

VA Greater Los Angeles Medical Center, Los Angeles, CA, USA.

Physical activity improves overall health and reduces the risk of many negative health outcomes and may be effective in improving cognition, independent functioning, and psychological health in older adults. Given the evidence linking physical activity with improvements in various aspects of health and functioning, interventions exploring pathways for decreasing risk of dementia in those with mild cognitive impairment (MCI) and improving outcomes for those with dementia are of critical importance. The present review highlights the work examining physical activity interventions in order to achieve a comprehensive understanding of the potential benefits of physical activity for individuals experiencing cognitive decline. Read More

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http://dx.doi.org/10.1155/2020/7807856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037481PMC
February 2020

Associations between Age-Related Changes in the Core Vestibular Projection Pathway and Balance Ability: A Diffusion Tensor Imaging Study.

Behav Neurol 2020 11;2020:2825108. Epub 2020 Feb 11.

Department of Physical Therapy, College of Health Sciences, Dankook University, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 31116, Republic of Korea.

Objective: We investigated the changes of the vestibulospinal tract (VST) and parietoinsular vestibular cortex (PIVC) using diffusion tensor imaging (DTI) and relation to balance between old and young healthy adults.

Methods: This study recruited eleven old adults (6 males, 5 females; mean age 63.36 ± 4. Read More

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http://dx.doi.org/10.1155/2020/2825108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036129PMC
February 2020

Framingham Risk Stratification of Middle-Aged Migraineurs.

Behav Neurol 2020 7;2020:7351214. Epub 2020 Feb 7.

Centre for Occupational Medicine, Medical School, University of Pécs, Pécs, Hungary.

. Migraine is a common primary headache disorder involving about 10-15% of the whole population. Several epidemiological and prospective studies showed a link between migraine (especially migraine with aura) and cardio- and cerebrovascular events. Read More

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http://dx.doi.org/10.1155/2020/7351214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029267PMC
February 2020

Associations of Alpha and Beta Interhemispheric EEG Coherences with Indices of Attentional Control and Academic Performance.

Behav Neurol 2020 5;2020:4672340. Epub 2020 Feb 5.

Department of Basic Sciences, American University of Antigua College of Medicine, Antigua and Barbuda.

. Heretofore, research on optimizing academic performance has suffered from an inability to translate what is known about an individual's learning behaviors to how effectively they are able to use the critical nodes and hubs in their cerebral cortex for learning. A previous study from our laboratory suggests that lower theta-beta ratios (TBRs) measured by EEG may be associated with higher academic performance in a medical school curriculum. Read More

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http://dx.doi.org/10.1155/2020/4672340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025044PMC
February 2020

Behavioural Changes in Mice after Getting Accustomed to the Mirror.

Behav Neurol 2020 3;2020:4071315. Epub 2020 Feb 3.

Department of Psychiatry, Kawasaki Medical School, Kurashiki 701-0192, Japan.

Patients with brain function disorders due to stroke or dementia may show inability to recognize themselves in the mirror. Although the cognitive ability to recognize mirror images has been investigated in many animal species, the animal species that can be used for experimentation and the mechanisms involved in recognition remain unclear. We investigated whether mice have the ability to recognize their mirror images. Read More

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http://dx.doi.org/10.1155/2020/4071315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023847PMC
February 2020

MST4 Kinase Inhibitor Hesperadin Attenuates Autophagy and Behavioral Disorder via the MST4/AKT Pathway in Intracerebral Hemorrhage Mice.

Behav Neurol 2020 3;2020:2476861. Epub 2020 Feb 3.

Key Laboratory of Noncoding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), The First Affiliated Hospital of Wannan Medical College, Wuhu, 241000 Anhui, China.

Background: The aim of this study was to explore the role of hesperadin in intracerebral hemorrhage (ICH) mice, with the involvement of the mammalian ste20-like kinase 4 (MST4)/AKT signaling pathway.

Methods: All mice were divided into four groups: sham group, sham+hesperidin group, ICH group, and ICH+hesperadin group. The effects of hesperadin were assessed on the basis of brain edema and neurobehavioral function. Read More

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http://dx.doi.org/10.1155/2020/2476861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023841PMC
February 2020

Effects of DCM Leaf Extract of (Fresen) on Locomotor Activity, Anxiety, and Exploration-Like Behaviors in High-Fat Diet-Induced Obese Rats.

Behav Neurol 2019 20;2019:7359235. Epub 2019 Dec 20.

Department of Biochemistry, Microbiology and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844-00100, Nairobi, Kenya.

Obesity is the main component of metabolic syndromes involving distinct etiologies that target different underlying behavioral and physiological functions within the brain structures and neuronal circuits. An alteration in the neuronal circuitry stemming from abdominal or central obesity stimulates a cascade of changes in neurochemical signaling that directly or indirectly mediate spontaneously emitted behaviors such as locomotor activity patterns, anxiety, and exploration. Pharmacological agents available for the treatment of neurologic disorders have been associated with limited potency and intolerable adverse effects. Read More

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http://dx.doi.org/10.1155/2019/7359235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942765PMC

Polysomnographic Findings in Fragile X Syndrome Children with EEG Abnormalities.

Behav Neurol 2019 3;2019:5202808. Epub 2019 Dec 3.

Department of Medical and Surgical Sciences, University "Magna Graecia", Catanzaro, Italy.

Fragile X syndrome (FXS) is a genetic syndrome with intellectual disability due to the loss of expression of the FMR1 gene located on chromosome X (Xq27.3). This mutation can suppress the fragile X mental retardation protein (FMRP) with an impact on synaptic functioning and neuronal plasticity. Read More

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http://dx.doi.org/10.1155/2019/5202808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915005PMC

Long-Term Voluntary Physical Exercise Exerts Neuroprotective Effects and Motor Disturbance Alleviation in a Rat Model of Parkinson's Disease.

Behav Neurol 2019 5;2019:4829572. Epub 2019 Dec 5.

Neuroscience Research Center, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan.

Background: Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder affecting 7-10 million individuals. The pathologic hallmark of PD is nigrostriatal dopaminergic neuron loss, leading to several motor and nonmotor disturbances, such as akinesia, gait disturbance, depression, and anxiety. Recent animal studies have demonstrated that physical exercise improves behavioral and neuropathological deficits in PD. Read More

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http://dx.doi.org/10.1155/2019/4829572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915149PMC

Therapeutic Approaches for Peripheral and Central Neuropathic Pain.

Behav Neurol 2019 21;2019:8685954. Epub 2019 Nov 21.

Department of Neurology, Interdisciplinary Excellence Centre, Faculty of Medicine, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.

Neuropathic pain is a chronic secondary pain condition, which is a consequence of peripheral or central nervous (somatosensory) system lesions or diseases. It is a devastating condition, which affects around 7% of the general population. Numerous etiological factors contribute to the development of chronic neuropathic pain. Read More

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http://dx.doi.org/10.1155/2019/8685954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906810PMC

Diverse Linguistic Development in Prelingually Deaf Children with Cochlear Implants.

Behav Neurol 2019 21;2019:1630718. Epub 2019 Nov 21.

Medical Centre of Phoniatrics, Padova, Italy.

The advent of cochlear implants has enormously improved the quality of sensory perception in deaf children. Notwithstanding these advantages, the current literature shows a substantial variability in language proficiency among implanted children. This case series explores the variability of language acquisition in congenitally deaf children with cochlear implants. Read More

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http://dx.doi.org/10.1155/2019/1630718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906843PMC

Feeding Behavior of Mice under Different Food Allocation Regimens.

Behav Neurol 2019 2;2019:1581304. Epub 2019 Dec 2.

Department of Psychiatry, Kawasaki Medical School, Okayama 701-0192, Japan.

Social interaction, a basic survival strategy for many animal species, helps maintain a social environment that has limited conflict. Social dominance has a dramatic effect on motivation. Recent evidence suggests that some primate and nonprimate species display aversive behavior toward food allocation regimens that differ from their peers. Read More

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http://dx.doi.org/10.1155/2019/1581304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913290PMC

Parkinson's Symptoms and Caregiver Burden and Mental Health: A Cross-Cultural Mediational Model.

Behav Neurol 2019 1;2019:1396572. Epub 2019 Dec 1.

Hospital Civil Fray Antonio Alcalde, Mexico.

Informal caregivers are critical in the care of individuals with Parkinson's disease (PD) and spend substantial time providing care, which may be associated with negative caregiver outcomes such as burden and mental health issues. Although research in the United States and Europe has generally supported these relations, there is very limited research on PD caregiving in Latin America. The current study examined the following connections in a sample of PD caregivers from the United States ( = 105) and Mexico ( = 148): (a) PD-related impairments (motor and nonmotor symptoms) and caregiver burden, (b) caregiver burden and caregiver mental health, and (c) PD-related impairments and mental health through caregiver burden. Read More

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http://dx.doi.org/10.1155/2019/1396572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913294PMC

Community's Perception and Attitude towards People with Epilepsy in Ethiopia.

Behav Neurol 2019 7;2019:4681958. Epub 2019 Nov 7.

Psychiatry Department, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Introduction: Most people with epilepsy suffer from a dual burden. In one hand, they struggle with the symptoms and disabilities on the other hand from misconceptions and stigma associated with it. But there are no recent studies which assess the community's perception and attitude. Read More

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http://dx.doi.org/10.1155/2019/4681958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878795PMC

CZYH Alleviates -Amyloid-Induced Cognitive Impairment and Inflammation Response via Modulation of JNK and NF-B Pathway in Rats.

Behav Neurol 2019 4;2019:9546761. Epub 2019 Nov 4.

Key Laboratory of Basic Pharmacology of Ministry of Education, Department of Pharmacology, Zunyi Medical University, Zunyi, Guizhou 563000, China.

Cu-Zhi-Yi-Hao (CZYH), an empirical formula of traditional Chinese medicine (TCM), has been used for amnesia treatment in clinical practice. However, its underlying pharmacological mechanism has not been fully illuminated. The current study was designed to investigate the neuroprotective effect of CZYH on a -amyloid 25-35- (A-) induced learning and memory deficit rat model. Read More

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http://dx.doi.org/10.1155/2019/9546761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875391PMC

Validation of a New Cognitive Screening Method for Stroke Patients.

Behav Neurol 2019 6;2019:2943603. Epub 2019 Nov 6.

University of Jyväskylä, Department of Psychology, Finland.

Objective: Two million adults under fifty years of age have a cerebral stroke every year worldwide. Neuropsychological assessment is the best way to identify poststroke cognitive dysfunction, but it is often time-consuming and can be tiring for the patient, and hospitals vary in their availability of neuropsychological expertise. A valid and reliable cognitive screening method could be advantageous in identifying patients who need comprehensive neuropsychological examination. Read More

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http://dx.doi.org/10.1155/2019/2943603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875250PMC

A Neuropsychological Rehabilitation Program for Cognitive Impairment in Psychiatric and Neurological Conditions: A Review That Supports Its Efficacy.

Behav Neurol 2019 21;2019:4647134. Epub 2019 Oct 21.

Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Avenida de las Universidades, 24, 48007 Bilbao, Biscay, Spain.

Neuropsychological rehabilitation has been the focus of much scientific research over the past decades due to its efficacy in different pathologies. Advances in the neuropsychology field have led to improvements and changes in neuropsychological interventions, which in turn have given rise to different approaches and rehabilitation programs. REHACOP is an integrative neuropsychological rehabilitation program designed by specialist neuropsychologists. Read More

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http://dx.doi.org/10.1155/2019/4647134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854258PMC

Epidemiology of Alzheimer's Disease and Dementia in Arab Countries: A Systematic Review.

Behav Neurol 2019 29;2019:3935943. Epub 2019 Oct 29.

Epidemiology and Biostatistics Section, Health Sciences Research Centre, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Background/objectives: Contrary to popular belief, the condition of dementia is not an actual discrete disease, but rather a group of symptoms, most notable of which is the disturbance of memory and social ability, often severe enough to impair daily functioning. As a result, it has been a major cause of functional deterioration among varying populations in the world. This study is aimed at reviewing the epidemiology of dementia in Arab countries in terms of its prevalence, distribution, and risk factors. Read More

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http://dx.doi.org/10.1155/2019/3935943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854962PMC
April 2020
1.642 Impact Factor

Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model.

Behav Neurol 2019 21;2019:1068260. Epub 2019 Oct 21.

Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China.

Objective: To explore the effects of sevoflurane on the latency and error times of the passive avoidance and levels of PSD-95 and AMPA receptors in the hippocampus. We evaluated the effects of sevoflurane on short-term memory in adult mice and explored the possible mechanism.

Methods: 144 Kunming mice (2-3 months, 30-35 g) were randomly divided into two groups A ( = 64) and B ( = 80) and received the dark-avoidance (DA) and step-down avoidance (SA) tests, respectively. Read More

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http://dx.doi.org/10.1155/2019/1068260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854262PMC

Behavioral and Neural Changes Induced by a Blended Essential Oil on Human Selective Attention.

Behav Neurol 2019 15;2019:5842132. Epub 2019 Oct 15.

School of Psychology and Cognitive Science, Shanghai Changning-ECNU Mental Health Center, East China Normal University, Shanghai 200062, China.

Selective attention refers to the selecting and preferential processing of specific information while simultaneously suppressing irrelevant distractors, activities linked to various cognitive skills and academic achievements. The influence of essential oils on the cognition of humans has been extensively explored. However, the effects of essential oils on human selective attention and the underlying neural mechanisms remain unclear. Read More

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http://dx.doi.org/10.1155/2019/5842132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815549PMC

Recent Medico-Legal Developments on the Issue of Epilepsy and Driver's License Requirements in the Italian and European Legislation.

Behav Neurol 2019 30;2019:7127956. Epub 2019 Sep 30.

Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Università "La Sapienza", 00161 Roma, Italy.

Epilepsy is a condition that comprises a group of neurological disorders characterized by seizures. Forms of epilepsy that produce abrupt bouts that cause lapses in consciousness may pose a major road safety problem for drivers who, while going through a seizure, could seriously harm themselves as well as others. A fundamental strategy for the purpose of reducing the risk of car accidents caused by epileptic drivers is constituted by prevention, in addition to adequate pharmacological therapies. Read More

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http://dx.doi.org/10.1155/2019/7127956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791238PMC

Prevalence and Associated Factors of Depressive Symptoms in Patients with Myasthenia Gravis: A Cross-Sectional Study of Two Tertiary Hospitals in Riyadh, Saudi Arabia.

Behav Neurol 2019 15;2019:9367453. Epub 2019 Sep 15.

Department of Internal Medicine, King Saud University Medical City and College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Objectives: This study is aimed at elucidating the prevalence of depression in patients with myasthenia gravis (MG) and examining the risk factors associated with depression.

Methods: We evaluated adult patients with MG who were recruited from two tertiary hospitals in the central region (Riyadh) of Saudi Arabia. Data were collected with a two-part standardized questionnaire: the first part included data on sociodemographic and clinical features of MG including disease type and duration, therapies, prednisolone dose, time of the last relapse, previous critical care unit admissions, MG status (controlled, partially controlled, or uncontrolled), and comorbid diseases; the second part included items from the previously validated Arabic version of the Patient Health Questionnaire-9 (PHQ-9). Read More

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http://dx.doi.org/10.1155/2019/9367453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766166PMC
February 2020

Social Aspects of Dementia Prevention from a Worldwide to National Perspective: A Review on the International Situation and the Example of Italy.

Authors:
Giovanna Ricci

Behav Neurol 2019 8;2019:8720904. Epub 2019 Sep 8.

School of Law, University of Camerino, Camerino, Italy.

At the moment, dementia is affecting around 47 million people worldwide, with a forecast amount of 135 million affected people in 2050. Dementia is a growing health concern worldwide with no treatment currently available, but only symptomatic medication. Effective interventions in the prevention and management of dementia are urgently needed to contain direct and indirect costs of this disease. Read More

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http://dx.doi.org/10.1155/2019/8720904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754867PMC
February 2020

Emotional Intelligence in Children with Severe Sleep-Related Breathing Disorders.

Behav Neurol 2019 5;2019:6530539. Epub 2019 Sep 5.

Department of Psychology, Educational Science and Human Movement, University of Palermo, Italy.

Background: Obstructive sleep apnea syndrome (OSAS) affects up to 4% of a pediatric population, with many comorbidities in the medium-long term. Functional alterations in the prefrontal cortex (PFC) may explain why OSAS impacts aspects such as executive functions, memory, motor control, attention, visual-spatial skills, learning, and mood regulation. Emotional intelligence (EI) is a complex neuropsychological function that could be impaired in many clinical conditions. Read More

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http://dx.doi.org/10.1155/2019/6530539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748194PMC
February 2020
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Efficacy and Safety of Intravenous Thrombolysis in Patients with Unknown Onset Stroke: A Meta-Analysis.

Behav Neurol 2019 3;2019:5406923. Epub 2019 Sep 3.

Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui Province, China.

Objectives: Unknown onset stroke (UOS) is usually excluded from intravenous thrombolysis concerning the unclear symptom onset time. Attempts have been done to use thrombolytic therapy in these patients. The current meta-analysis was done to examine the efficacy and safety of intravenous thrombolysis in UOS. Read More

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http://dx.doi.org/10.1155/2019/5406923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745097PMC
February 2020
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Using Partial Directed Coherence to Study Alpha-Band Effective Brain Networks during a Visuospatial Attention Task.

Behav Neurol 2019 3;2019:1410425. Epub 2019 Sep 3.

School of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, China.

Previous studies have shown that the neural mechanisms underlying visual spatial attention rely on top-down control information from the frontal and parietal cortexes, which ultimately amplifies sensory processing of stimulus occurred at the attended location relative to those at unattended location. However, the modulations of effective brain networks in response to stimulus at attended and unattended location are not yet clear. In present study, we collected event-related potentials (ERPs) from 15 subjects during a visual spatial attention task, and a partial directed coherence (PDC) method was used to construct alpha-band effective brain networks of two conditions (targets at attended and nontargets at unattended location). Read More

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http://dx.doi.org/10.1155/2019/1410425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745104PMC
February 2020
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Effects of Systematic Categorization Training on Cognitive Performance in Healthy Older Adults and in Adults with Traumatic Brain Injury.

Behav Neurol 2019 29;2019:9785319. Epub 2019 Jul 29.

Department of Psychology and Center for Applied Neuroscience, University of Cyprus, Nicosia, Cyprus.

This study investigated the effects of hierarchical cognitive training using the categorization program (CP), designed initially for adults with cognitive deficits associated with traumatic brain injury (TBI). Fifty-eight participants were included: a group of fifteen young adults with TBI (ages 18-48), another group of fifteen noninjured young adults (ages 18-50), and two groups of adults over 60 randomly assigned into the experimental group ( = 14) or the control group ( = 14). Following neuropsychological testing, the two young adult groups and the experimental older adult group received the CP training for 10-12 weeks. Read More

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http://dx.doi.org/10.1155/2019/9785319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732608PMC
February 2020

Long-Term Follow-Up of Disability, Cognitive, and Emotional Impairments after Severe Traumatic Brain Injury.

Behav Neurol 2019 27;2019:9216931. Epub 2019 Aug 27.

Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, Umeå, Sweden.

Aim: To assess the clinical course of disability, cognitive, and emotional impairments in patients with severe TBI (s-TBI) from 3 months to up to 7 years post trauma.

Methods: A prospective cohort study of s-TBI in northern Sweden was conducted. Patients aged 18-65 years with acute Glasgow Coma Scale 3-8 were assessed with the Glasgow Outcome Scale Extended (GOSE), the Hospital Anxiety and Depression Scale (HADS), and the Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) at 3 months, 1 year, and 7 years after the injury. Read More

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http://dx.doi.org/10.1155/2019/9216931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732613PMC
February 2020