1,015 results match your criteria Behavioural Neurology[Journal]


Frontal Anatomical Correlates of Cognitive and Speech Motor Deficits in Amyotrophic Lateral Sclerosis.

Behav Neurol 2019 13;2019:9518309. Epub 2019 Mar 13.

Sunnybrook Research Institute, Hurvitz Brain Sciences Program, Toronto, Canada.

The goal of this study was to identify neurostructural frontal lobe correlates of cognitive and speaking rate changes in amyotrophic lateral sclerosis (ALS). 17 patients diagnosed with ALS and 12 matched controls underwent clinical, bulbar, and neuropsychological assessment and structural neuroimaging. Neuropsychological testing was performed via a novel computerized frontal battery (ALS-CFB), based on a validated theoretical model of frontal lobe functions, and focused on testing energization, executive function, emotion processing, theory of mind, and behavioral inhibition via antisaccades. Read More

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http://dx.doi.org/10.1155/2019/9518309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436339PMC

The Clinical and Vascular Characteristics of RNF213 c.14576G>A Variant-Related Intracranial Major Artery Disease in China.

Behav Neurol 2019 12;2019:7908392. Epub 2019 Mar 12.

Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

Background And Purpose: Recently, several studies indicated the c.14576G>A variant on the ring finger protein 213 (RNF213), a founder variant of moyamoya diseases (MMD), was associated with non-MMD intracranial major artery stenosis/occlusion (non-MMD ICASO). We proposed that RNF213 variant-related ICASO including MMD might be a special entity with its own characteristics based on a genetic background. Read More

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https://www.hindawi.com/journals/bn/2019/7908392/
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http://dx.doi.org/10.1155/2019/7908392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434291PMC
March 2019
1 Read

The Incidence of Diagnosis of Munchausen Syndrome, Other Factitious Disorders, and Malingering.

Behav Neurol 2019 3;2019:3891809. Epub 2019 Mar 3.

Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

Background: Systematic studies on factitious disorders and malingering in large populations are rare. To address this issue, we performed a nationwide epidemiological study in Norway on the incidence of these diagnoses in an unselected patient population. In particular, we tried to confirm the diagnoses and to estimate the contribution of Munchausen syndrome to the spectrum of factitious disorders. Read More

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http://dx.doi.org/10.1155/2019/3891809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421757PMC
March 2019
1 Read

Traumatic Brain Injury by Weight-Drop Method Causes Transient Amyloid- Deposition and Acute Cognitive Deficits in Mice.

Behav Neurol 2019 3;2019:3248519. Epub 2019 Mar 3.

Laboratory of Neurobiophysics, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki 769-2193, Japan.

There has been growing awareness of the correlation between an episode of traumatic brain injury (TBI) and the development of Alzheimer's disease (AD) later in life. It has been reported that TBI accelerated amyloid- (A) pathology and cognitive decline in the several lines of AD model mice. However, the short-term and long-term effects of TBI by the weight-drop method on amyloid- pathology and cognitive performance are unclear in wild-type (WT) mice. Read More

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https://www.hindawi.com/journals/bn/2019/3248519/
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http://dx.doi.org/10.1155/2019/3248519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421814PMC
March 2019
3 Reads

A Repeated Measures Pilot Comparison of Trajectories of Fluctuating Endogenous Hormones in Young Women with Traumatic Brain Injury, Healthy Controls.

Behav Neurol 2019 12;2019:7694503. Epub 2019 Feb 12.

Department of Physical Medicine and Rehabilitation, University of Pittsburgh, PA, USA.

Objective: To compare baseline and 72-hour hormone levels in women with traumatic brain injury (TBI) and controls.

Setting: Hospital emergency department.

Participants: 21 women ages 18-35 with TBI and 21 controls. Read More

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https://www.hindawi.com/journals/bn/2019/7694503/
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http://dx.doi.org/10.1155/2019/7694503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390250PMC
February 2019
4 Reads

Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury.

Behav Neurol 2019 10;2019:1312934. Epub 2019 Feb 10.

Neurological Institute, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.

Background: Empathy has been conceptualized as comprising a cognitive and an emotional component, the latter being further divided into direct and indirect aspects, which refer, respectively, to the explicit evaluation of the observer's feelings while attending someone in an emotional situation and to the physiological response of the observer. Empathy has been previously investigated in several neurological disorders.

Objective: This study is aimed at investigating empathy in patients with spinal cord injury (SCI). Read More

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http://dx.doi.org/10.1155/2019/1312934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387693PMC
February 2019
1 Read

The Effect of Metformin in Experimentally Induced Animal Models of Epileptic Seizure.

Behav Neurol 2019 4;2019:6234758. Epub 2019 Feb 4.

Mekelle University, College of Health Sciences, Department of Pharmacology and Toxicology, Ethiopia.

Background: Epilepsy is one of the common neurological illnesses which affects millions of individuals globally. Although the majority of epileptic patients have a good response for the currently available antiepileptic drugs (AEDs), about 30-40% of epileptic patients are developing resistance. In addition to low safety profiles of most of existing AEDs, there is no AED available for curative or disease-modifying actions for epilepsy so far. Read More

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http://dx.doi.org/10.1155/2019/6234758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378775PMC
February 2019
1 Read

Assessing Treatment Fidelity within an Epilepsy Randomized Controlled Trial: Seizure First Aid Training for People with Epilepsy Who Visit Emergency Departments.

Behav Neurol 2019 3;2019:5048794. Epub 2019 Feb 3.

Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

Purpose: To measure fidelity with which a group seizure first aid training intervention was delivered within a pilot randomized controlled trial underway in the UK for adults with epilepsy who visit emergency departments (ED) and informal carers. Estimates of its effects, including on ED use, will be produced by the trial. Whilst hardly ever reported for trials of epilepsy interventions-only one publication on this topic exists-this study provides the information on treatment fidelity necessary to allow the trial's estimates to be accurately interpreted. Read More

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http://dx.doi.org/10.1155/2019/5048794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378079PMC
February 2019
6 Reads

Screening for Problematic Internet Use May Help Identify Impulse Control Disorders in Parkinson's Disease.

Behav Neurol 2019 3;2019:4925015. Epub 2019 Feb 3.

Department of Neurology, University of Pécs Medical School, Pécs, Hungary.

Background: Impulse control disorders in Parkinson's disease (PD) represent emerging problems with potentially devastating consequences. The standard screening methods for impulse control disorders are clinically imperfect. Although it is rarely reported, many patients utilize the Internet to fulfill their compulsive behaviors because of its easy accessibility. Read More

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http://dx.doi.org/10.1155/2019/4925015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378069PMC
February 2019

Influence of Environmental Factors on Social Participation Post-Stroke.

Behav Neurol 2019 16;2019:2606039. Epub 2019 Jan 16.

Department of Occupational Therapy, MGH Institute of Health Professions, Boston MA, USA.

Objectives: For rehabilitation professionals to adequately address meaningful participation in social activities with their patients after a stroke, there must be a better understanding of neurobehavior, that is, how neurological impairment and its sequelae and environmental factors support or limit social participation. The current study examines how stroke severity (NIH Stroke Scale), its impact on perceived mobility (Stroke Impact Scale mobility domain), and the environment (MOS Social Support-Positive Social Interactions scale and Measure of Stroke Environment receptivity and built environment domains) influence social participation (Activity Card Sort: ACS).

Methods: A correlational, cross-sectional design examined the relationships among neurological impairment, perceived limitations in activity, environmental factors, and social participation. Read More

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http://dx.doi.org/10.1155/2019/2606039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360065PMC
January 2019
5 Reads

Molecular Mechanisms of Neurodegeneration Related to Hexanucleotide Repeat Expansion.

Behav Neurol 2019 15;2019:2909168. Epub 2019 Jan 15.

Department of Neuroscience, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia.

Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. The neuropathological correlate of FTD is frontotemporal lobar degeneration (FTLD), characterized by tau-, TDP-43-, and FUS-immunoreactive neuronal inclusions. An earlier discovery that a hexanucleotide repeat expansion mutation in chromosome 9 open reading frame 72 () gene causes ALS and FTD established a special subtype of ALS and FTLD with TDP-43 pathology (C9FTD/ALS). Read More

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http://dx.doi.org/10.1155/2019/2909168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350563PMC
January 2019
4 Reads
1.642 Impact Factor

Visuoperceptual Impairment in Children with NF1: From Early Visual Processing to Procedural Strategies.

Behav Neurol 2019 13;2019:7146168. Epub 2019 Jan 13.

Developmental Neurology Division, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133 Milan, Italy.

Visual-spatial impairment has long been considered a hallmark feature of neurofibromatosis type 1 (NF1). No study investigating the cognitive and neuropsychological profile of NF1 used the Rey Complex Figure Test (RCFT) task as the primary measure of visual-perceptual abilities taking into consideration all functions involved including the strategic processing style. We compared 18 children with NF1, 17 siblings (S), and 18 typically developing children (TD) at intelligence scale and RCFT copy, recall, and recognition trials; we also evaluated the copy strategy as a measure of a visual-processing style. Read More

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http://dx.doi.org/10.1155/2019/7146168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348799PMC
January 2019

Psychiatric Assessment in Patients with Mild Temporal Lobe Epilepsy.

Behav Neurol 2019 14;2019:4139404. Epub 2019 Jan 14.

Neurology Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy.

Objectives: The findings of previous studies focused on personality disorders in epileptic patients are difficult to interpret due to nonhomogeneous samples and noncomparable methods. Here, we aimed at studying the personality profile in patients with mild temporal lobe epilepsy (mTLE) with psychiatric comorbidity.

Materials And Methods: Thirty-five patients with mTLE (22 males, mean age 40. Read More

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https://www.hindawi.com/journals/bn/2019/4139404/
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http://dx.doi.org/10.1155/2019/4139404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348858PMC
January 2019
19 Reads

A Randomized Clinical Trial of a Functional Electrical Stimulation Mimic to Gait Promotes Motor Recovery and Brain Remodeling in Acute Stroke.

Behav Neurol 2018 18;2018:8923520. Epub 2018 Dec 18.

Department of Rehabilitation Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Functional electrical stimulation can improve motor function after stroke. The mechanism may involve activity-dependent plasticity and brain remodeling. The aim of our study was to investigate the effectiveness of a patterned electrical stimulation FES mimic to gait in motor recovery among stroke survivors and to investigate possible mechanisms through brain fMRI. Read More

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http://dx.doi.org/10.1155/2018/8923520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312612PMC
December 2018
2 Reads

Psychometric Properties of the Dental Activities Test: An Exploratory Factor Analysis in Older Adults with Cognitive Impairment.

Authors:
Xi Chen Wen Liu

Behav Neurol 2018 17;2018:8625916. Epub 2018 Dec 17.

College of Nursing, University of Iowa, Iowa City, Iowa, USA.

Objective: The Dental Activities Test (DAT) was developed to be used by dental, nursing, and other health professionals to assess the ability of persons with dementia to perform oral health-related activities and aid care planning. The instrument was designed as a unitary scale and has excellent internal consistency, test-retest reliability, interrater reliability, and construct validity. This study examines the underlying factor structure of the DAT among older adults in assisted living settings. Read More

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http://dx.doi.org/10.1155/2018/8625916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311855PMC
December 2018
1 Read

System Framework of Robotics in Upper Limb Rehabilitation on Poststroke Motor Recovery.

Behav Neurol 2018 13;2018:6737056. Epub 2018 Dec 13.

Baoxing Hospital, Shenzhen 518100, China.

Neurological impairments such as stroke cause damage to the functional mobility of survivors and affect their ability to perform activities of daily living. Recently, robotic treatment for upper limb stroke rehabilitation has received significant attention because it can provide high-intensity and repetitive movement therapy. In this review, the current status of upper limb rehabilitation robots is explored. Read More

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https://www.hindawi.com/journals/bn/2018/6737056/
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http://dx.doi.org/10.1155/2018/6737056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311736PMC
December 2018
9 Reads

Sociodemographic, Electrophysiological, and Biochemical Profiles in Children with Attention Deficit Hyperactivity Disorder and/or Epilepsy.

Behav Neurol 2018 29;2018:8932817. Epub 2018 Nov 29.

Clinical Physiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt.

Attention deficit hyperactivity disorder (ADHD) is among the most prevalent neurobehavioral disorders affecting children worldwide. The prevalence of ADHD is higher in children with epilepsy. Despite the plethora of conducted work, the precise cause of ADHD is not identified yet. Read More

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http://dx.doi.org/10.1155/2018/8932817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305032PMC
April 2019
1 Read

Sociodemographic, Clinical Variables, and Quality of Life in Patients with Epilepsy in Mekelle City, Northern Ethiopia.

Behav Neurol 2018 2;2018:7593573. Epub 2018 Dec 2.

Department of Pharmacology and Toxicology, School of Pharmacy, Mekelle University, Ethiopia.

Background: Epilepsy is a chronic neurological disorder characterized by unprovoked recurrent seizure episodes. The disease has detrimental effects on social, cognitive, psychological, and physical components of life consequently quality of life of the patients. The level of the effect of the disease on quality life is influenced by different factors including the use of antiepileptic medications. Read More

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https://www.hindawi.com/journals/bn/2018/7593573/
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http://dx.doi.org/10.1155/2018/7593573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305035PMC
April 2019
9 Reads

Practice Variability Combined with Task-Oriented Electromyographic Biofeedback Enhances Strength and Balance in People with Chronic Stroke.

Behav Neurol 2018 26;2018:7080218. Epub 2018 Nov 26.

School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.

Objectives: To investigate the effects of practice variability combined with task-oriented electromyographic biofeedback (EMGBFB) on strength and balance in people with chronic stroke.

Methods: Thirty-three participants were randomly assigned into the constant force EMGBFB tibialis anterior (TA) exercise (constant) group, the variable force EMGBFB tibialis anterior exercise (variable) group, or the upper extremity exercise without EMGBFB (control) group. Subjects in each group received 6 weekly sessions of exercise training (18 sessions, 40 minutes each). Read More

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http://dx.doi.org/10.1155/2018/7080218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287124PMC

Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs: Focus on Topiramate, Levetiracetam, and Perampanel.

Behav Neurol 2018 15;2018:2064027. Epub 2018 Nov 15.

Department of Clinical Chemistry and Pharmacology, Skåne University Hospital, Lund, Sweden.

Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). Knowledge of the incidence, risk factors, and the underlying mechanisms of AB induced by AEDs may help to facilitate management and reduce the risk of such side effects. The exact incidence of AB as an adverse effect of AEDs is difficult to estimate, but frequencies up to 16% have been reported. Read More

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http://dx.doi.org/10.1155/2018/2064027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276511PMC
April 2019
1 Read

Behavioural and Cognitive Changes in Lewy Body Dementias.

Behav Neurol 2018;2018:2404191. Epub 2018 Nov 11.

Department of Exercise and Health Promotion, College of Education, Chinese Culture University, Taipei, Taiwan.

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https://www.hindawi.com/journals/bn/2018/2404191/
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http://dx.doi.org/10.1155/2018/2404191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252200PMC
November 2018
19 Reads

Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients.

Behav Neurol 2018 31;2018:5969137. Epub 2018 Oct 31.

Department of Neurology, Eleanor and Lou Gehrig MD/ALS Research Center, CUMC, USA.

Objective: To evaluate longitudinal cognitive/behavioral change over 12 months in participants enrolled in the ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS).

Methods: We analyzed data from 294 ALS participants, 134 of whom were studied serially. Change over time was evaluated controlling for age, sex, symptom duration, education, race, and ethnicity. Read More

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https://www.hindawi.com/journals/bn/2018/5969137/
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http://dx.doi.org/10.1155/2018/5969137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234441PMC
April 2019
19 Reads
1.642 Impact Factor

Therapeutic Strategies for Poststroke Neurological Behavior: From Molecular to Cellular.

Behav Neurol 2018;2018:6215348. Epub 2018 Oct 28.

Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1155/2018/6215348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230415PMC
October 2018

Apathy Is Correlated with Widespread Diffusion Tensor Imaging (DTI) Impairment in Amyotrophic Lateral Sclerosis.

Behav Neurol 2018 22;2018:2635202. Epub 2018 Oct 22.

Department of Psychology, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.

Apathy is recognized as the most common behavioral change in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), a multisystem neurodegenerative disorder. Particularly, apathy has been reported to be associated with poor ALS prognosis. However, the brain microstructural correlates of this behavioral symptom, reported as the most common in ALS, have not been completely elucidated. Read More

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https://www.hindawi.com/journals/bn/2018/2635202/
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http://dx.doi.org/10.1155/2018/2635202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217902PMC
April 2019
17 Reads

Intravenous Immunoglobulin Therapy Administered Early after Narcolepsy Type 1 Onset in Three Patients Evaluated by Clinical and Polysomnographic Follow-Up.

Behav Neurol 2018 15;2018:1671072. Epub 2018 Oct 15.

Department of Neurology, Sleep Disorders Center, CIRCSom, Hôpital Civil, 1 place de l'Hôpital, 67091 Strasbourg, France.

Narcolepsy type 1 is a rare disabling sleep disorder mainly characterized by excessive daytime sleepiness and cataplexy, an emotion-triggered sudden loss of muscle tone. Patients have a selective degeneration of hypocretin-producing neurons in the dorsolateral posterior hypothalamus with growing evidence supporting the hypothesis of an autoimmune mechanism. Few case studies that reported intravenous immunoglobulin therapy (IVIg) suggest the efficacy of IVIg when administered early after disease onset, but the results are controversial. Read More

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https://www.hindawi.com/journals/bn/2018/1671072/
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http://dx.doi.org/10.1155/2018/1671072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205306PMC
April 2019
14 Reads

Cognitive-Enhancing Effect of a Hydroethanolic Extract of against Memory Impairment Induced by Aluminum Chloride in BALB/c Mice.

Behav Neurol 2018 4;2018:2057219. Epub 2018 Oct 4.

Drug and Toxicology Information Service (DaTIS), School of Pharmacy and Department of Clinical Pharmacology, College of Health Sciences, University of Zimbabwe, P.O. Box A 178, Avondale, Harare, Zimbabwe.

is a bulbous plant indigenous to many parts of Southern Africa. Extracts of have gained interest since the discovery of various alkaloids, few of which possess acetylcholinesterase inhibitory activity. The present study was performed to evaluate the effect of a crude hydroethanolic extract of against aluminum chloride-induced memory impairment in mice using the Morris water maze and the novel object recognition task. Read More

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https://www.hindawi.com/journals/bn/2018/2057219/
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http://dx.doi.org/10.1155/2018/2057219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193330PMC
April 2019
13 Reads

Stroke Survivor and Caregiver Perspectives on Post-Stroke Visual Concerns and Long-Term Consequences.

Behav Neurol 2018 4;2018:1463429. Epub 2018 Oct 4.

Division of Rehabilitation Sciences, School of Health Professions, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA.

Approximately 800,000 people in the United States have a stroke annually. Up to two thirds of stroke survivors have some visual problems, which result in disability and can affect survivors' overall rehabilitation outcomes. Although some post-stroke visual impairments can be corrected and respond well to intervention, ocular signs can be subtle and may not be recognized or reported by the stroke survivor but rather by a vigilant caregiver. Read More

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https://www.hindawi.com/journals/bn/2018/1463429/
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http://dx.doi.org/10.1155/2018/1463429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193320PMC
April 2019
12 Reads
1.642 Impact Factor

Associations between Attention-Deficit Hyperactivity Disorder (ADHD) Treatment and Patient Nutritional Status and Height.

Behav Neurol 2018 2;2018:7341529. Epub 2018 Oct 2.

Pediatrics Department, School of Medicine, University of Sao Paulo, Av. Dr. Enéas Carvalho de Aguiar, 647, 05403.000, São Paulo, SP, Brazil.

Attention-deficit hyperactivity disorder (ADHD) has been found to co-occur frequently with obesity, although the reasons for this association are unknown. The aim of this study was to compare the nutritional profile of a Brazilian cohort of ADHD patients with that of the general population and to analyze the association between ADHD drug treatment (with methylphenidate), nutritional status, and height of these individuals. In the first phase of the study, we designed the nutritional and height profile of 93 ADHD patients (5. Read More

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http://dx.doi.org/10.1155/2018/7341529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189682PMC
April 2019
1 Read

Comparing Sensitivity and Specificity of Addenbrooke's Cognitive Examination-I, III and Mini-Addenbrooke's Cognitive Examination in Parkinson's Disease.

Behav Neurol 2018 2;2018:5932028. Epub 2018 Oct 2.

Institute of Behavioral Sciences, University of Pécs, Pécs, Hungary.

Background: Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by numerous motor and nonmotor symptoms. Neurocognitive disorders (NCD) are one of the most troublesome problems and their diagnosis is often challenging.

Methods: We compared the sensitivity and specificity of several versions of Addenbrooke Cognitive Examination (ACE, ACE-III, and Mini-ACE) on 552 subjects with PD. Read More

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http://dx.doi.org/10.1155/2018/5932028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189663PMC
January 2019
25 Reads

Effects of (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats.

Behav Neurol 2018 30;2018:5751864. Epub 2018 Sep 30.

Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon.

The present work was undertaken to evaluate the ability of aqueous extract and its major component 7-methoxycoumarin (MC) to improve scopolamine-induced spatial memory impairment in ovariectomized Wistar rats. For this to be done, 10 sham-operated and 30 postmenopausal-like rats were randomly distributed in eight groups ( = 5) and treated with distilled water (2 mL/250 g), estradiol valerate (1 mg/kg BW), piracetam (1.5 mg/kg BW), aqueous extract (50 and 200 mg/kg BW), or MC (1 mg/kg BW) for 21 consecutive days. Read More

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https://www.hindawi.com/journals/bn/2018/5751864/
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http://dx.doi.org/10.1155/2018/5751864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186347PMC
January 2019
2 Reads
1.642 Impact Factor

Gait and Conditioned Fear Impairments in a Mouse Model of Comorbid TBI and PTSD.

Behav Neurol 2018 20;2018:6037015. Epub 2018 Sep 20.

VA Portland Health Care System, Portland, OR, USA.

Study Objectives: Traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) commonly cooccur. Approaches to research and treatment of these disorders have been segregated, despite overlapping symptomology. We and others have hypothesized that comorbid TBI + PTSD generates worse symptoms than either condition alone. Read More

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https://www.hindawi.com/journals/bn/2018/6037015/
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http://dx.doi.org/10.1155/2018/6037015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171258PMC
January 2019
11 Reads

The Long-Term Efficacy and Safety of Carotid Artery Stenting among the Elderly: A Single-Center Study in China.

Behav Neurol 2018 12;2018:4707104. Epub 2018 Sep 12.

Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.

Compared to carotid endarterectomy, carotid artery stenting (CAS) is reportedly associated with higher perioperative risks in elderly patients. To verify the long-term safety and efficacy of CAS with embolic protection in elderly patients, we retrospectively reviewed the medical records of patients with carotid stenosis treated between January 2003 and March 2010 at the Department of Neurology of a large university hospital in China. We included patients with symptomatic, moderate, or severe carotid stenosis of atherosclerotic etiology (other etiologies were excluded), with a disability score ≤ 3 on the modified Rankin Scale, and who received CAS instead of carotid endarterectomy. Read More

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https://www.hindawi.com/journals/bn/2018/4707104/
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http://dx.doi.org/10.1155/2018/4707104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157176PMC
January 2019
1 Read
1.642 Impact Factor

Scoping Review: The Trajectory of Recovery of Participation Outcomes following Stroke.

Behav Neurol 2018 9;2018:5472018. Epub 2018 Sep 9.

Occupational Therapy, Department of Community and Clinical Allied Health, School of Allied Health, La Trobe University, Melbourne, VIC, Australia.

Participation is a central concept in health and well-being and healthcare, yet operationalizing this concept has been difficult. Its definition, uses in healthcare, and impacts on recovery require ongoing research. Our review question goes like this: from the longitudinal evidence investigating participation among stroke survivors, what are the patterns of participation recovery in stroke survivors over time, and what interventions are used to improve participation? To fully understand these questions, we also ask, how is participation defined in the stroke literature, and what are the measures of participation used in the stroke literature? A systematic scoping review was undertaken using the search terms "stroke," "longitudinal," "participation," and "outcome" in seven databases. Read More

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https://www.hindawi.com/journals/bn/2018/5472018/
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http://dx.doi.org/10.1155/2018/5472018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151208PMC
January 2019
12 Reads

Altered Small-World Networks in First-Episode Schizophrenia Patients during Cool Executive Function Task.

Behav Neurol 2018 5;2018:2191208. Epub 2018 Sep 5.

School of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, China.

At present, little is known about brain functional connectivity and its small-world topologic properties in first-episode schizophrenia (SZ) patients during cool executive function task. In this paper, the Trail Making Test-B (TMT-B) task was used to evaluate the cool executive function of first-episode SZ patients and electroencephalography (EEG) data were recorded from 14 first-episode SZ patients and 14 healthy controls during this cool executive function task. Brain functional connectivity between all pairs of EEG channels was constructed based on mutual information (MI) analysis. Read More

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http://dx.doi.org/10.1155/2018/2191208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145160PMC
January 2019

Scoping Review of the Driving Behaviour of and Driver Training Programs for People on the Autism Spectrum.

Behav Neurol 2018 28;2018:6842306. Epub 2018 Aug 28.

School of Occupational Therapy Social Work and Speech Pathology, Faculty of Health Sciences, Curtin University, GPO Box U1987, Perth, WA 6845, Australia.

Gaining a driver's licence represents increased independence and can lead to improved quality of life for individuals and their families. Learning to drive a motor vehicle and maintaining safe on-road skills are often more difficult for people on the autism spectrum. Many countries currently have no autism-specific licencing requirements for learner drivers, and there is a general lack of ASD-specific support and training packages for individuals, their families, and driving instructors. Read More

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http://dx.doi.org/10.1155/2018/6842306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136574PMC
January 2019
3 Reads
1.642 Impact Factor

Indication of Disrupted Temporal Structure in the Case of Thought Blocks in Schizophrenia: The Role of the Metastable Balance.

Behav Neurol 2018 2;2018:4031207. Epub 2018 Sep 2.

Medical School, 1st Psychiatric Department, Eginition Hospital, Athens University, 72-74 Vas. Sofias Ave., 115 28 Athens, Greece.

This study is aimed at investigating probable disruption of the metastable balance relevant to a disruption of the mental processes observed in the neurophenomenal level. This disruption was found to occur under dense auditory verbal hallucinations (AVHs) which are accompanied by thought blocking (TB) phenomena. The entropy that quantifies the complexity of the spontaneous coupling has been used to describe the observed transitions. Read More

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https://www.hindawi.com/journals/bn/2018/4031207/
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http://dx.doi.org/10.1155/2018/4031207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139220PMC
January 2019
17 Reads

Effect of Carotid Artery Morphological Variations on Cognitive Function.

Behav Neurol 2018 16;2018:7290431. Epub 2018 Aug 16.

Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.

Background: Carotid artery morphological variations (CAMV) are common variations on medical imaging; the effects of CAMV on cognition were still unknown. This study is aimed at investigating whether carotid artery morphological variations (CAMV) cause cognitive impairment.

Methods: Hospitalized patients from March 2017 to October 2017 who underwent digital subtract angiography (DSA) were divided into non-CAMV group, T-type group, K-type group, and C-type group according to their carotid artery morphology. Read More

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http://dx.doi.org/10.1155/2018/7290431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116395PMC
January 2019
11 Reads

Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice.

Behav Neurol 2018 12;2018:6583267. Epub 2018 Aug 12.

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.

Objectives: To investigate the role of Scriptaid in reducing brain injury after intracerebral hemorrhage (ICH) in mice.

Methods: An ICH model was constructed by injecting autologous blood into the right basal ganglia in mice. The animals were administered 3. Read More

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http://dx.doi.org/10.1155/2018/6583267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109529PMC
October 2018
17 Reads

Hypertriglyceridemia Is Associated with Reduced Leukoaraiosis Severity in Patients with a Small Vessel Stroke.

Behav Neurol 2018 9;2018:1361780. Epub 2018 Aug 9.

Department of Radiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.

Intracranial hemorrhage or microbleeds and leukoaraiosis have an overlap in biology. Hyperlipidemia may reduce the risk of ICH or cerebral microbleeds; studies focusing on the relationship between different lipid profiles and severity of periventricular hyperintensities (PVH) and subcortical white matter lesions (SWMLs) in the cerebral small vessel disease are limited. . Read More

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https://www.hindawi.com/journals/bn/2018/1361780/
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http://dx.doi.org/10.1155/2018/1361780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109573PMC
October 2018
13 Reads

Inhibiting of GRASP65 Phosphorylation by DL-3-N-Butylphthalide Protects against Cerebral Ischemia-Reperfusion Injury via ERK Signaling.

Behav Neurol 2018 1;2018:5701719. Epub 2018 Aug 1.

Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Background And Purpose: The aim of this study was to explore the role of DL-3-n-butylphthalide (NBP) in cerebral ischemia-reperfusion injury (CIRI) mice model. The involvement of extracellular signal-regulated kinase (ERK) signaling pathway was also investigated.

Methods: All mice were divided into five groups: sham-operated group, CIRI group, NBP pretreatment group, NBP treatment group, and NBP pretreatment + treatment group. Read More

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http://dx.doi.org/10.1155/2018/5701719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093058PMC
October 2018
25 Reads

Ceftriaxone Treatment for Neuronal Deficits: A Histological and MEMRI Study in a Rat Model of Dementia with Lewy Bodies.

Behav Neurol 2018 1;2018:4618716. Epub 2018 Aug 1.

Division of Urology, Department of Surgery, Tungs' Taichung Metroharbor Hospital, Taichung 43503, Taiwan.

Dementia with Lewy bodies (DLB) is characterized by neuronal deficits and -synuclein inclusions in the brain. Ceftriaxone (CEF), a -lactam antibiotic, has been suggested as a therapeutic agent in several neurodegenerative disorders for its abilities to counteract glutamate-mediated toxicity and to block -synuclein polymerization. By using manganese-enhanced magnetic resonance imaging (MEMRI) and immunohistochemistry, we measured the effects of CEF on neuronal activity and -synuclein accumulation in the brain in a DLB rat model. Read More

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http://dx.doi.org/10.1155/2018/4618716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092970PMC
October 2018
16 Reads
1.642 Impact Factor

Exploring the Neuroplastic Effects of Biofeedback Training on Smokers.

Behav Neurol 2018 29;2018:4876287. Epub 2018 Jul 29.

Lab of Medical Physics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki (AUTH), 54124 Thessaloniki, Greece.

Smoking and stress cooccur in different stages of a nicotine addiction cycle, affecting brain function and showing additive impact on different physiological responses. Resting-state functional connectivity has shown potential in identifying these alterations. Nicotine addiction has been associated with detrimental effects on functional integrity of the central nervous system, including the organization of resting-state networks. Read More

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http://dx.doi.org/10.1155/2018/4876287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087614PMC
October 2018
1 Read

Behavioural and Cognitive Changes in Neurodegenerative Diseases and Brain Injury.

Behav Neurol 2018 25;2018:4935915. Epub 2018 Jul 25.

Department of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.

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http://dx.doi.org/10.1155/2018/4935915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083604PMC
January 2019
15 Reads

The Pathogenesis of Necroptosis-Dependent Signaling Pathway in Cerebral Ischemic Disease.

Behav Neurol 2018 22;2018:6814393. Epub 2018 Jul 22.

Department of Neurology, First Affiliated Hospital of Wannan Medical College, No. 2, ZheShanXi Road, Wuhu 241001, China.

Necroptosis is the best-described form of regulated necrosis at present, which is widely recognized as a component of caspase-independent cell death mediated by the concerted action of receptor-interacting protein kinase 1 (RIPK1) and receptor-interacting protein kinase 3 (RIPK3). Mixed-lineage kinase domain-like (MLKL) was phosphorylated by RIPK3 at the threonine 357 and serine 358 residues and then formed tetramers and translocated onto the plasma membrane, which destabilizes plasma membrane integrity leading to cell swelling and membrane rupture. Necroptosis is downstream of the tumor necrosis factor (TNF) receptor family, and also interaction with NOD-like receptor pyrin 3 (NLRP3) induced inflammasome activation. Read More

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http://dx.doi.org/10.1155/2018/6814393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081565PMC
October 2018
21 Reads

PPAR- Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage.

Behav Neurol 2018 9;2018:7646104. Epub 2018 Jul 9.

Department of Neurology, The Second Hospital, Shanxi Medical University, 382 WuYi St., Taiyuan, Shanxi 030001, China.

Background And Purpose: PPAR- is a transcriptional factor which is associated with promoting hematoma clearance and reducing neurological dysfunction after intracerebral hemorrhage (ICH). Haptoglobin- (Hp-) hemoglobin- (Hb-) CD163 acts as a main pathway to Hb scavenging after ICH. The effect of PPAR- on the Hp-Hb-CD163 signaling pathway has not been reported. Read More

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http://dx.doi.org/10.1155/2018/7646104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079602PMC
October 2018
6 Reads

Corrigendum to "Mechanism of Restoration of Forelimb Motor Function after Cervical Spinal Cord Hemisection in Rats: Electrophysiological Verification".

Behav Neurol 2018 18;2018:5627890. Epub 2018 Jul 18.

Department of Orthopaedic Surgery, Kyorin University, 6-20-2 Shinkawa, Mitaka-shi, Tokyo 181-0004, Japan.

[This corrects the article DOI: 10.1155/2017/7514681.]. Read More

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http://dx.doi.org/10.1155/2018/5627890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079613PMC
July 2018
1 Read

Increased Risk of Dementia in Patients with Antidepressants: A Meta-Analysis of Observational Studies.

Behav Neurol 2018 10;2018:5315098. Epub 2018 Jul 10.

Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

Antidepressants are the most commonly and widely used medication for its effectiveness in the treatment of anxiety and depression. A few epidemiological studies have documented that antidepressant is associated with increased risk of dementia so far. Here, our aim is to assess the association between antidepressant use and risk of dementia in elderly patients. Read More

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http://dx.doi.org/10.1155/2018/5315098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079596PMC
October 2018
4 Reads
1.642 Impact Factor

Quality of Life in Patients with Dementia with Lewy Bodies.

Behav Neurol 2018 5;2018:8320901. Epub 2018 Jul 5.

Department of Neurology, Mackay Memorial Hospital, Taipei, Taiwan.

Dementia with Lewy bodies (DLB) is a complex, multisymptom disorder. When making decisions regarding the treatment of DLB, the patient's quality of life (QoL) should always be the main consideration. To our knowledge, this is the first review article focusing on the QoL in DLB patients. Read More

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http://dx.doi.org/10.1155/2018/8320901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057352PMC
October 2018
8 Reads

Hand Dexterity Impairment in Patients with Cervical Myelopathy: A New Quantitative Assessment Using a Natural Prehension Movement.

Behav Neurol 2018 4;2018:5138234. Epub 2018 Jul 4.

Department of Integrative Physiology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan.

Cervical myelopathy (CM) caused by spinal cord compression can lead to reduced hand dexterity. However, except for the 10 sec grip-and-release test, there is no objective assessment system for hand dexterity in patients with CM. Therefore, we evaluated the hand dexterity impairment of patients with CM objectively by asking them to perform a natural prehension movement. Read More

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http://dx.doi.org/10.1155/2018/5138234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057419PMC
October 2018
1 Read

COGEVIS: A New Scale to Evaluate Cognition in Patients with Visual Deficiency.

Behav Neurol 2018 25;2018:4295184. Epub 2018 Jun 25.

AP-HP, Department of Neurology, Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A), Hôpital de la Pitié-Salpêtrière, 75013 Paris, France.

We evaluated the cognitive status of visually impaired patients referred to low vision rehabilitation (LVR) based on a standard cognitive battery and a new evaluation tool, named the COGEVIS, which can be used to assess patients with severe visual deficits. We studied patients aged 60 and above, referred to the LVR Hospital in Paris. Neurological and cognitive evaluations were performed in an expert memory center. Read More

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http://dx.doi.org/10.1155/2018/4295184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036847PMC
October 2018
1 Read