2,304,934 results match your criteria Behaviour & Information Technology[Journal]


CIDR estrous synchronization in the Arabian Oryx (Oryx leucoryx).

Theriogenology 2019 Apr 15;132:113-117. Epub 2019 Apr 15.

Department of Biochemistry, Faculty of Veterinary Medicine, Alexandria University, Egypt; Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, King Faisal University, Saudi Arabia.

In Jordan, the Arabian Oryx (Oryx leucoryx) is considered among the most important wild ungulates. The Arabian Oryx is listed as vulnerable species according to the International Union for Conservation of Nature (IUCN). Based on author's knowledge, estrus synchronization in the Arabian Oryx has never been investigated. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2019.04.017DOI Listing

Improved electrocatalytic activity of Au@FeO magnetic nanoparticles for sensitive dopamine detection.

Colloids Surf B Biointerfaces 2019 Apr 16;180:1-8. Epub 2019 Apr 16.

Electroorganic Division, CSIR-Central Electrochemical Research Institute, Karaikudi 630003, India. Electronic address:

Substantially, noble metals are important for the development of low-cost, sensitive, selective, superior performance, and portable electrochemical sensors. Herein, we describe gold (Au) nanoparticles (NPs) systematically decorated with magnetic FeO nanocomposites on the fabrication of sensitive dopamine sensor is described. Magnetic Au@FeO nanocomposites were prepared by reducing HAuCl on the surfaces of FeO nanoparticles. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.034DOI Listing

The mechanical behavior of brain surrogates manufactured from silicone elastomers.

J Mech Behav Biomed Mater 2019 Apr 16;95:180-190. Epub 2019 Apr 16.

Department of Mechanical Engineering, Iowa State University of Science and Technology, 2529 Union Drive, Ames, IA, 50011, USA. Electronic address:

The ongoing conflict against terrorism has resulted in an escalation of blast-induced traumatic brain injuries (bTBI) caused by improvised explosive devices (IEDs). The destructive IEDs create a blast wave that travels through the atmosphere. Blast-induced traumatic brain injuries, attributed to the blast wave, can cause life-threatening injuries and fatalities. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17516161183167
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http://dx.doi.org/10.1016/j.jmbbm.2019.04.005DOI Listing
April 2019
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Newer vs. older CAD/CAM burs: Influence of bur experience on the fatigue behavior of adhesively cemented simplified lithium-disilicate glass-ceramic restorations.

J Mech Behav Biomed Mater 2019 Apr 9;95:172-179. Epub 2019 Apr 9.

Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp) - Institute of Science and Technology, São José dos Campos, Brazil. Electronic address:

This study evaluated the effect of the CAD/CAM burs experience (newer vs older as consequence of the milling sequence) on fatigue failure load (FFL), number of cycles for failure (CFF), and survival rates of lithium disilicate glass-ceramic simplified restorations adhesively cemented to a dentin analogue substrate. Three sets of CAD/CAM burs were used to mill disc-shaped ceramic specimens (1 bur set - 18 milled discs with 10 mm diameter and 1.5 mm thickness), considering the bur experience as a result of the milling sequence to compose the study groups: G1-6 - discs obtained from the 1st to 6th milling of each bur set; G7-12 - specimens from the 7th to 12th milling; G13-18 - discs from the 13th to 18th. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.002DOI Listing

The long-term stability of Fe-As coprecipitates at pH 4 and 7: Mechanisms controlling the arsenic behavior.

J Hazard Mater 2019 Apr 15;374:276-286. Epub 2019 Apr 15.

Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110016, China. Electronic address:

Hydrometallurgical Fe-As coprecipitates, which are amorphous in nature, could re-crystallize gradually and pose risks of contamination to the environment. However, the mechanisms controlling the As behavior when the Fe-As coprecipitates stored at different pHs is still not fully understood. This work systematically investigated the fate of As and the transformation process of the coprecipitates (Fe/As = ˜4) at different pHs and temperatures. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.04.054DOI Listing

Degradation studies of Ibrutinib under stress conditions: Characterisation and structural elucidation of novel degradants.

J Pharm Biomed Anal 2019 Apr 12;172:9-17. Epub 2019 Apr 12.

Department of Engineering Chemistry, Andhra University, Visakhapatnam, A.P., 530003, India.

The aim of the research work is to study the degradation behaviour of Ibrutinib (IBN) which is performed under different stress conditions according to International Conference on Harmonization guidelines (ICH). The study included monitoring degradation of the Ibrutinib drug under acidic, base, oxidation, thermal and photolytic conditions followed by isolation and characterisation of degradation products (DP) by Liquid Chromatography Mass Spectrometry (LCMS), High resolution Mass Spectrometry (HR-MS/MS) and Nuclear Magnetic Resonance (NMR) studies. The IBN drug is stable under oxidation, thermal and photolytic conditions. Read More

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http://dx.doi.org/10.1016/j.jpba.2019.04.010DOI Listing

Multi-environment evaluation of oil accumulation pattern parameters in olive.

Plant Physiol Biochem 2019 Apr 14;139:485-494. Epub 2019 Apr 14.

IFAPA Centro "Alameda del Obispo", Avda Menéndez Pidal s/n, 14004, Córdoba, Spain. Electronic address:

The pattern of olive oil accumulation is of paramount importance in olive because its influence in determining final oil yield and optimal harvesting date. In this work, we have evaluated the genetic and environment influence on the olive oil accumulation pattern. For that purpose, a set of cultivars and breeding selections planted in a multi-environment trial was evaluated in two consecutive harvest seasons. Read More

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http://dx.doi.org/10.1016/j.plaphy.2019.04.016DOI Listing

Impact of maternal depression trajectories on offspring socioemotional competences at age 11: 2004 Pelotas Birth Cohort.

J Affect Disord 2019 Mar 22;253:8-17. Epub 2019 Mar 22.

Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, 2nd floor, Sao Paulo, SP, CEP 01246-903, Brazil; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

Background: Maternal depression is associated with impairments in child behavioural and emotional development, although the effect of exposure to maternal depression until adolescence is underexplored in most studies. This longitudinal study examined the association between maternal depressive symptoms trajectories and offspring socioemotional competences at age 11.

Methods: We included 3,437 11-year-old adolescents from the 2004 Pelotas Birth Cohort Study. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.072DOI Listing

Altered whole brain functional connectivity pattern homogeneity in medication-free major depressive disorder.

J Affect Disord 2019 Apr 8;253:18-25. Epub 2019 Apr 8.

Key Laboratory of Adolescent Cyberpsycology and Behavior (CCNU) of Ministry of Education, Central China Normal University, Wuhan 430079, China; School of Psychology, Central China Normal University, Wuhan 430079, China. Electronic address:

Background: Many previous studies have revealed abnormal functional connectivity patterns between brain areas underlying the onset of major depressive disorder (MDD) using resting-state functional magnetic resonance imaging (rs-fMRI). However, how to exactly characterize the voxel-wise whole brain functional connectivity pattern changes in MDD remains unclear, which will provide more convincing evidence for localizing the exactly functional connectivity abnormality in MDD.

Methods: In this study, we employed our newly developed whole brain functional connectivity homogeneity (FcHo) method to identify the voxel-wise changes of functional connectivity patterns in 27 medication-free MDD patients and 34 gender-, age-, and education level-matched healthy controls (HC). Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.040DOI Listing

Genome-wide annotation and comparative analysis of cuticular protein genes in the noctuid pest Spodoptera litura.

Insect Biochem Mol Biol 2019 Apr 19. Epub 2019 Apr 19.

State Key Laboratory of Silkworm Genome Biology, Biological Science Research Center, Southwest University, Chongqing, 400716, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400716, China. Electronic address:

Insect cuticle is considered an adaptable and versatile building material with roles in the construction and function of exoskeleton. Its physical properties are varied, as the biological requirements differ among diverse structures and change during the life cycle of the insect. Although the bulk of cuticle consists basically of cuticular proteins (CPs) associated with chitin, the degree of cuticular sclerotization is an important factor in determining its physical properties. Read More

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http://dx.doi.org/10.1016/j.ibmb.2019.04.012DOI Listing

Experience-dependent mechanisms in the regulation of parental care.

Front Neuroendocrinol 2019 Apr 19. Epub 2019 Apr 19.

University of California, Davis, Department of Psychology, One Shields Ave. Davis, CA 95616.

Maternal behavior is a defining characteristic of mammals, which is regulated by a core, conserved neural circuit. However, mothering behavior is not always a default response to infant conspecifics. For example, initial fearful, fragmented or aggressive responses toward infants in laboratory rats and mice can give way to highly motivated and organized caregiving behaviors following appropriate hormone exposure or repeated experience with infants. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00913022183012
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http://dx.doi.org/10.1016/j.yfrne.2019.04.002DOI Listing
April 2019
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Behavioral profile of intermittent vs continuous access to a high fat diet during adolescence.

Behav Brain Res 2019 Apr 19. Epub 2019 Apr 19.

Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología, Universitat de València, Avda. Blasco Ibáñez, 21, 46010 Valencia, Spain. Electronic address:

Over the past few years, the effects of a high-fat diet (HFD) on cognitive functions have been broadly studied as a model of obesity, although no studies have evaluated whether these effects are maintained after the cessation of this diet. In addition, the behavioral effects of having a limited access to an HFD (binge-eating pattern) are mostly unknown, although they dramatically increase the vulnerability to drug use in contrast to having continuous access. Thus, the aim of the present study was to compare the effects of an intermittent versus a continuous exposure to an HFD during adolescence on cognition and anxiety-like behaviors, as well as to study the changes observed after the interruption of this diet. Read More

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http://dx.doi.org/10.1016/j.bbr.2019.04.005DOI Listing

Metabolic and Behavioral Responses of Predators to Prey Nutrient Content.

J Insect Physiol 2019 Apr 19. Epub 2019 Apr 19.

Department of Integrative Biology, Oklahoma State University, 501 Life Science West, Stillwater, Oklahoma, 74075, USA.

Predators feed on a diversity of prey that can vary widely in nutrient content. While prey nutrient content is known to have important consequences for life history traits, less is known about how it affects physiology and behavior. The purpose of this study was to test how diet affected the physiology and behavior of the wolf spider Hogna carolinensis. Read More

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http://dx.doi.org/10.1016/j.jinsphys.2019.04.006DOI Listing

Urotherapy in the treatment of children and adolescents with bladder and bowel dysfunction: a systematic review.

J Pediatr (Rio J) 2019 Apr 19. Epub 2019 Apr 19.

Universidade de Brasília (UnB), Departamento de Enfermagem, Brasília, DF, Brazil; Society for Pediatric Urology (SPU), United States; McGill University, Ingram School of Nursing, Quebec, Canada; Shriners Hospital for Children, Quebec, Canada.

Objective: To identify and describe the protocols and clinical outcomes of urotherapy interventions in children and adolescents with bladder bowel dysfunction.

Method: Systematic review carried out in June 2018 on MEDLINE/PubMed, CINAHL, EMBASE, SciELO, Cochrane, and PsycInfo databases. Clinical trials and quasi-experimental studies carried out in the last ten years in children and/or adolescents with bladder and bowel symptoms and application of at least one component of urotherapy were included. Read More

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http://dx.doi.org/10.1016/j.jped.2019.02.007DOI Listing

A Facial-Action Imposter: How Head Tilt Influences Perceptions of Dominance From a Neutral Face.

Psychol Sci 2019 Apr 22:956797619838762. Epub 2019 Apr 22.

Department of Psychology, The University of British Columbia.

Research on face perception tends to focus on facial morphology and the activation of facial muscles while ignoring any impact of head position. We raise questions about this approach by demonstrating that head movements can dramatically shift the appearance of the face to shape social judgments without engaging facial musculature. In five studies (total N = 1,517), we found that when eye gaze was directed forward, tilting one's head downward (compared with a neutral angle) increased perceptions of dominance, and this effect was due to the illusory appearance of lowered and V-shaped eyebrows caused by a downward head tilt. Read More

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http://dx.doi.org/10.1177/0956797619838762DOI Listing

Fish Collagen and Hydroxyapatite reinforced PLGA fibrous membrane for guided bone regeneration.

Biomacromolecules 2019 Apr 22. Epub 2019 Apr 22.

The purpose of this study was to fabricate a low-immunogenicity fish collagen (FC) and bioactive nano-hydroxyapatite (n-HA) enhanced poly (lactide-co-glycolide) (PLGA) nanofibrous membrane for guided bone regeneration (GBR) via electrospinning. The physicochemical properties and morphology study revealed that FC and n-HA particles were homogeneously dispersed in the PLGA fibrous matrix. Notably, the formation of enhanced polymeric chain network due to the interaction between FC and PLGA significantly improved the tensile strength of the PLGA membrane. Read More

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http://dx.doi.org/10.1021/acs.biomac.9b00267DOI Listing

Gas chromatography mass spectrometry analysis of non-hydrolyzed sulfated steroids by degradation product formation.

Drug Test Anal 2019 Apr 22. Epub 2019 Apr 22.

Department of Diagnostic Sciences, Doping Control Laboratory, Ghent University, Technologiepark 30 B, B-9052, Zwijnaarde, Belgium.

Steroid detection and identification remains a key issue in toxicology, drug testing, medical diagnostics, food safety control and doping control. In this study, we evaluate the capabilities and usefulness of analyzing non-hydrolyzed sulfated steroids with gas chromatography mass spectrometry (GC-MS) instead of the conventionally applied liquid chromatography MS (LC-MS) approach. Sulfates of 31 steroids were synthesized and their MS and chromatographic behavior was studied by chemical ionization GC triple quadrupole MS (CI GC-MS/MS) and low energy electron ionization GC quadrupole time-of-flight MS (LE-EI GC-QTOF-MS). Read More

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http://dx.doi.org/10.1002/dta.2606DOI Listing

Ambivalence in the Early Years of Marriage: Impact on Ambulatory Blood Pressure and Relationship Processes.

Ann Behav Med 2019 Apr 22. Epub 2019 Apr 22.

Mannheim Institute of Public Health, Universität Heidelberg, Heidelberg, Germany.

Background: Marriage is associated with lower cardiovascular morbidity and mortality, but quality matters. Marriages characterized by ambivalent behaviors (containing both highly positive and highly negative behaviors concurrently) may not confer the same cardiovascular benefits as characterized by purely positive behavior. Ambivalence is assumed to take time to develop but couples in the early years of marriage may already exhibit ambivalent behaviors and thus be at increased risk for future cardiovascular events. Read More

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https://academic.oup.com/abm/advance-article/doi/10.1093/abm
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http://dx.doi.org/10.1093/abm/kaz017DOI Listing

Confidence boosts serial dependence in orientation estimation.

J Vis 2019 Apr;19(4):25

University of Wisconsin-Madison, Department of Psychology and Department of Psychiatry, Madison, WI.

In the absence of external feedback, a decision maker must rely on a subjective estimate of their decision accuracy in order to appropriately guide behavior. Normative models of perceptual decision-making relate subjective estimates of internal signal quality (e.g. Read More

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http://jov.arvojournals.org/article.aspx?doi=10.1167/19.4.25
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http://dx.doi.org/10.1167/19.4.25DOI Listing
April 2019
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Pupylated proteins are subject to broad proteasomal degradation specificity and differential depupylation.

PLoS One 2019 22;14(4):e0215439. Epub 2019 Apr 22.

Institute of Molecular Biology and Biophysics, Department of Biology, ETHZ, Zurich, Switzerland.

In actinobacteria, post-translational modification of proteins with prokaryotic ubiquitin-like protein Pup targets them for degradation by a bacterial proteasome assembly consisting of the 20S core particle (CP) and the mycobacterial proteasomal ATPase (Mpa). Modification of hundreds of cellular proteins with Pup at specific surface lysines is carried out by a single Pup-ligase (PafA, proteasome accessory factor A). Pupylated substrates are recruited to the degradative pathway by binding of Pup to the N-terminal coiled-coil domains of Mpa. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215439PLOS

Bifidobacterium longum R0175 attenuates post-myocardial infarction depressive-like behaviour in rats.

PLoS One 2019 22;14(4):e0215101. Epub 2019 Apr 22.

CIUSSS du Nord-de-l'Île-de-Montréal, Hôpital Sacré-Cœur, Montréal, Canada.

Caspase-3 activation in the limbic system and depressive-like symptoms are observed after an acute myocardial infarction (MI) and studies suggest that inflammation may play a significant role. Combined treatment with the probiotic strains Bifidobacterium longum and Lactobacillus helveticus in rats has been shown to attenuate caspase-3 activation and depressive-like behaviour together with a reduction in pro-inflammatory cytokines. The present study was designed to determine the respective contribution of these two strains on caspase-3 activity in the limbic system and on depressive-like behaviour. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215101PLOS

Temporal pattern separation in hippocampal neurons through multiplexed neural codes.

PLoS Comput Biol 2019 Apr 22;15(4):e1006932. Epub 2019 Apr 22.

Department of Neuroscience, University of Wisconsin-Madison, WI, United States of America.

Pattern separation is a central concept in current theories of episodic memory: this computation is thought to support our ability to avoid confusion between similar memories by transforming similar cortical input patterns of neural activity into dissimilar output patterns before their long-term storage in the hippocampus. Because there are many ways one can define patterns of neuronal activity and the similarity between them, pattern separation could in theory be achieved through multiple coding strategies. Using our recently developed assay that evaluates pattern separation in isolated tissue by controlling and recording the input and output spike trains of single hippocampal neurons, we explored neural codes through which pattern separation is performed by systematic testing of different similarity metrics and various time resolutions. Read More

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http://dx.doi.org/10.1371/journal.pcbi.1006932DOI Listing

Finding the balance between model complexity and performance: Using ventral striatal oscillations to classify feeding behavior in rats.

PLoS Comput Biol 2019 Apr 22;15(4):e1006838. Epub 2019 Apr 22.

Department of Psychiatry, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, New Hampshire, United States of America.

The ventral striatum (VS) is a central node within a distributed network that controls appetitive behavior, and neuromodulation of the VS has demonstrated therapeutic potential for appetitive disorders. Local field potential (LFP) oscillations recorded from deep brain stimulation (DBS) electrodes within the VS are a pragmatic source of neural systems-level information about appetitive behavior that could be used in responsive neuromodulation systems. Here, we recorded LFPs from the bilateral nucleus accumbens core and shell (subregions of the VS) during limited access to palatable food across varying conditions of hunger and food palatability in male rats. Read More

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http://dx.doi.org/10.1371/journal.pcbi.1006838DOI Listing

Analyses of Livestock-Associated Pan-Genomes Suggest Virulence Is Not Primary Interest in Evolution of Its Genome.

OMICS 2019 Apr;23(4):224-236

1 Department of Animal Behaviour & Physiology, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamil Nadu, India.

is not only part of normal flora but also an opportunistic pathogen relevant to microbial genomics, public health, and veterinary medicine. In addition to being a well-known human pathogen, causes various infections in economically important livestock animals such as cows, sheep, goats, and pigs. There are very few studies that have examined the pan-genome of or the host-specific strains' pan-genomes. Read More

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http://dx.doi.org/10.1089/omi.2019.0005DOI Listing

QUANTIFYING THE SEVERITY OF GIRAFFE SKIN DISEASE VIA PHOTOGRAMMETRY ANALYSIS OF CAMERA TRAP DATA.

J Wildl Dis 2019 Apr 22. Epub 2019 Apr 22.

1   Research on the Ecology of Carnivores and Their Prey Laboratory, Department of Fisheries and Wildlife, Michigan State University, 480 Wilson Road, 13 Natural Resources Building, East Lansing, Michigan 48824, USA.

Developing techniques to quantify the spread and severity of diseases afflicting wildlife populations is important for disease ecology, animal ecology, and conservation. Giraffes () are in the midst of a dramatic decline, but it is not known whether disease is playing an important role in the broad-scale population reductions. A skin disorder referred to as giraffe skin disease (GSD) was recorded in 1995 in one giraffe population in Uganda. Read More

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Veterinary Behavior: Assessment of Veterinarians' Training, Experience, and Comfort Level with Cases.

J Vet Med Educ 2019 Apr 22:1-12. Epub 2019 Apr 22.

Studies of US animal shelters consistently indicate that behavior is often a major reason for relinquishment and, thereby, euthanasia of millions of dogs and cats annually. Even though this is an area in which veterinarians can intervene to support the human-animal bond, prior research has documented that they frequently do not bring the topic up during appointments. This study explored veterinarians' training in animal behavior and behavioral medicine, along with their level of comfort in treating common behavioral problems. Read More

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http://dx.doi.org/10.3138/jvme.0318-035r1DOI Listing
April 2019
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Combination of Carvacrol and Thymol: Antimicrobial Activity Against and Antioxidant Activity.

Foodborne Pathog Dis 2019 Apr 19. Epub 2019 Apr 19.

2 Department of Food Hygiene and Technology, University of León, Campus de Vegazana, León, Spain.

Plant and essential oil extracts have been used for some time as antimicrobials and antioxidants, although little is known about the interactions between the main components of these plant materials. This knowledge could help to design more potent antimicrobial and antioxidant mixtures. Carvacrol and thymol, the main components of the essential oils of the Lamiaceae family of plants, were assessed in combination to evaluate their antioxidant activity and antimicrobial effect against 19 strains of () of different origins (clinical, meat, milk, and other) and mostly (12) enterotoxin producers. Read More

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http://dx.doi.org/10.1089/fpd.2018.2594DOI Listing

Solvation Structure of Poly(benzyl methacrylate) in a Solvate Ionic Liquid: Preferential Solvation of Li-Glyme Complex Cation.

J Phys Chem B 2019 Apr 22. Epub 2019 Apr 22.

We report the solvation structure of a lower critical solution temperature (LCST)-type thermoresponsive polymer in a solvate ionic liquid (SIL, i.e., an ionic liquid comprising solvate ions) to elucidate the predominant interaction for dissolution of the thermoresponsive polymer in SIL at a low temperature. Read More

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http://dx.doi.org/10.1021/acs.jpcb.9b02458DOI Listing

Understanding Water Structure in an Ion-Pair Solvation Shell in the Vicinity of a Water/Membrane Interface.

J Phys Chem B 2019 Apr 22. Epub 2019 Apr 22.

The anomalous properties of interfacial water at the surface of a lipid membrane and their implications on nearby chemical processes are well recognized. However, we have found that ion pairing thermodynamics may not be significantly affected by interfacial water in a classical, non-polarizable force field. To trace the root cause of such a counter-intuitive finding, we performed atomistic molecular dynamics simulations to explore the impact of polarizable interactions and characterize the hydration structure of a sodium chloride (NaCl) ion pair at the surface of a model lipid membrane and in a bulk phase. Read More

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http://dx.doi.org/10.1021/acs.jpcb.9b01331DOI Listing

Law and Disorder: Special Stacking Units-Building the Intergrowth CeCoGe.

Inorg Chem 2019 Apr 22. Epub 2019 Apr 22.

Center for Nanophysics and Advanced Materials, Department of Physics , University of Maryland , College Park , Maryland 20742 , United States.

A new structure type of composition CeCoGe was grown out of a molten Sn flux. CeCoGe crystallizes in the orthorhombic space group Cmcm, with highly anisotropic lattice parameters of a = 4.3293(5) Å, b = 55. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.9b00350DOI Listing

Structures, Single-Molecule Magnets, and Fluorescent Properties of Four Dinuclear Lanthanide Complexes Based on 4-Azotriazolyl-3-hydroxy-2-naphthoic Acid.

Inorg Chem 2019 Apr 22. Epub 2019 Apr 22.

Guangzhou Key Laboratory for Environmentally Functional Materials and Technology, School of Chemistry and Chemical Engineering , Guangzhou University , Guangzhou 510006 , P. R. China.

Four isostructural dinuclear lanthanide complexes based on 4-azotriazolyl-3-hydroxy-2-naphthoic acid (HATNA) and 3-hydroxy-2-naphthoic acid (HNA) ligands, {[Ln(HATNA)(HNA)(HO)]·6DMF} (Ln = Dy (1), Tb (2), Sm (3), Eu (4); DMF = N, N-dimethylformamide) have been prepared and characterized by X-ray diffraction crystallography, dc/ac magnetic characterization, and fluorescent spectrometry. The crystallographic data reveal dinuclear lanthanide cores of complexes 1-4, bridged by phenoxo and μ carboxyl groups. Each nine-coordinated Ln(III) ion is located in a slightly distorted monocapped square antiprism. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.9b00260DOI Listing

Sexual cues influence cocaine-induced locomotion, anxiety and the immunoreactivity of estrogen receptor alpha and tyrosine hydroxylase in both sexes.

J Neuroendocrinol 2019 Apr 22:e12720. Epub 2019 Apr 22.

College of Biological Sciences and Engineering, North Minzu University, Yinchuan, Ningxia, 750021, China.

Dyadic physical social interaction influences cocaine-seeking behavior, but whether limited sexual cues (LSCs) from an opposite-sex partner influence behavioral responses to cocaine is unclear. We investigated this issue using a cylindrical wire cage containing a stimulus mouse (of the opposite sex); the subject mouse had access to this stimulus mouse during a "binge" injection pattern (injected with cocaine or saline vehicle twice a day, at 6-h intervals). Following the second injection, locomotion and anxiety-like behaviors were examined using the open-field and elevated plus-maze test, while estrogen receptor alpha (ERα) and tyrosine hydroxylase (TH) immunoreactivity were also examined. Read More

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http://dx.doi.org/10.1111/jne.12720DOI Listing

Homozygous stop mutation in AHR causes autosomal recessive foveal hypoplasia and infantile nystagmus.

Brain 2019 Apr 22. Epub 2019 Apr 22.

Molecular Genetics Laboratory, Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany.

Herein we present a consanguineous family with three children affected by foveal hypoplasia with infantile nystagmus, following an autosomal recessive mode of inheritance. The patients showed normal electroretinography responses, no signs of albinism, and no anterior segment or brain abnormalities. Upon whole exome sequencing, we identified a homozygous mutation (c. Read More

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https://academic.oup.com/brain/advance-article/doi/10.1093/b
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http://dx.doi.org/10.1093/brain/awz098DOI Listing
April 2019
1 Read

Association of Cumulative Socioeconomic and Health-Related Disadvantage With Disparities in Smoking Prevalence in the United States, 2008 to 2017.

JAMA Intern Med 2019 Apr 22. Epub 2019 Apr 22.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles.

Importance: Understanding emerging patterns of smoking disparities among disadvantaged populations can guide tobacco control policy.

Objective: To estimate disparities in smoking prevalence associated with the number of socioeconomic and health-related disadvantages faced by a population among US adults from 2008 to 2017.

Design, Setting, And Participants: Nationally representative cross-sectional annual household-based probability sample of US noninstitutionalized residents. Read More

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http://dx.doi.org/10.1001/jamainternmed.2019.0192DOI Listing

Swimming Induced Paralysis to Assess Dopamine Signaling in Caenorhabditis elegans.

J Vis Exp 2019 Apr 3(146). Epub 2019 Apr 3.

Harriet Wilkes Honors College, Florida Atlantic University, John D MacArthur Campus; Brain Institute, Florida Atlantic University; Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University;

The swimming assay described in this protocol is a valid tool to identify proteins regulating the dopaminergic synapses. Similar to mammals, dopamine (DA) controls several functions in C. elegans including learning and motor activity. Read More

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http://dx.doi.org/10.3791/59243DOI Listing

Behavioral Tracking and Neuromast Imaging of Mexican Cavefish.

J Vis Exp 2019 Apr 6(146). Epub 2019 Apr 6.

Department of Biology, University of Hawai'i at Mānoa;

Cave-dwelling animals have evolved a series of morphological and behavioral traits to adapt to their perpetually dark and food-sparse environments. Among these traits, foraging behavior is one of the useful windows into functional advantages of behavioral trait evolution. Presented herein are updated methods for analyzing vibration attraction behavior (VAB: an adaptive foraging behavior) and imaging of associated mechanosensors of cave-adapted tetra, Astyanax mexicanus. Read More

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http://dx.doi.org/10.3791/59099DOI Listing

An osteoclast-like giant cell tumor embedded in the mural nodule of a pancreatic mucinous cystic neoplasm: A case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15246

Peking University China-Japan Friendship School of Clinical Medicine.

Rationale: Mucinous cystic neoplasms (MCNs) are relatively rare lesions, accounting for 2%-5% of all exocrine pancreatic neoplasms. MCNs mainly occur in women (female:male ratio = 20:1), with a peak incidence in the 5th decade of life. Osteoclast-like giant cell tumors (OGCTs) are rare and relatively aggressive neoplasms, comprising <1% of all pancreatic carcinomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000015246DOI Listing

Where Do You Think You Are? A Grounded Theory Study of the Critical Factors Triggering the Existence and Fueling the Persistence of Incivility in Nursing.

Nurs Educ Perspect 2019 May/Jun;40(3):133-138

About the Authors The authors are faculty at Barry University College of Nursing and Health Sciences, Miami Shores, Florida. Roselle Ann Samson-Mojares, PhD, RN, is an assistant professor, Undergraduate Program. Claudette R. Chin, PhD, ARNP, is an assistant professor, Graduate Program. Mary K. Colvin, PhD, RN, CNE, is an associate professor and the program director, Undergraduate Program. Tony Umadhay, PhD, CRNA, ARNP, is an associate dean. This study was funded by the Florida Nurses Foundation, 2014 Undine Sams and Friends Research Grant Fund, and a Sigma Theta Tau International-Lambda Chi Chapter 2016 Research Grant. The authors are grateful to the RNs who volunteered to be part of this study. For more information, contact Dr. Samson-Mojares at

Background: Incivility in health care settings was first identified in 1976. The Institute of Medicine has called for a safer health care environment, and the Joint Commission emphasizes that disruptive behavior compromises patient safety. Incivility in nursing is a topic of interest, yet it had not been explored as a social process. Read More

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http://dx.doi.org/10.1097/01.NEP.0000000000000397DOI Listing

Imaging vs quantitative sensory testing to predict chronic pain treatment outcomes.

Authors:
Karen D Davis

Pain 2019 May;160 Suppl 1:S59-S65

Department of Surgery and Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

In this article, I review the concept of personalized pain management and consider how brain imaging and quantitative sensory testing can be used to derive biomarkers of chronic pain treatment outcome. I review how different modalities of brain imaging can be used to acquire information about brain structure and function and how this information can be linked to individual measures of pain. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001479DOI Listing

Hedonic drinking engages a supraspinal inhibition of thermal nociception in adult rats.

Pain 2019 05;160(5):1059-1069

Department of Neurobiology and Physiology, School of Dentistry, Dental Research Institute, Seoul National University, Seoul, Korea.

The taste of sucrose is commonly used to provide pain relief in newborn humans and is innately analgesic to neonatal rodents. In adulthood, sucrose remains a strong motivator to feed, even in potentially hazardous circumstances (ie, threat of tissue damage). However, the neurobiological mechanisms of this endogenous reward-pain interaction are unclear. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001482DOI Listing
May 2019
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High-Functioning Autism, Severe Anxiety, and Bullying in a 26 Year Old.

J Dev Behav Pediatr 2019 Apr 16. Epub 2019 Apr 16.

Research Institute in Developmental Medicine, Johannes Kepler University, Linz, Austria.

Case: Peter is a 26-year-old group home resident in Austria with a history of poor peer relationships, including being bullied, and previous diagnoses of attention-deficit hyperactivity disorder, Asperger syndrome, social anxiety, depression, and developmental coordination disorder. Consultation from our international neurodevelopmental team was requested for severe anxiety and avoidance of social interactions. He reported 4 or more spontaneous anxiety episodes per day. Read More

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http://dx.doi.org/10.1097/DBP.0000000000000674DOI Listing

Diagnosis and treatment of patients with comorbid substance use disorder and adult attention-deficit and hyperactivity disorder: a review of recent publications.

Curr Opin Psychiatry 2019 Apr 16. Epub 2019 Apr 16.

Amsterdam Institute of Addiction Research (AIAR), Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

Purpose Of Review: Attention-deficit and hyperactivity disorder (ADHD) often presents with comorbid substance use disorders (SUD). Due to similarities in key symptoms of both disorders and suboptimal efficacy of the available treatments, clinicians are faced with difficulties in the diagnosis and treatment of these patients with both disorders. This review addresses recent publications between 2017 and 2019 on the etiology, prevalence, diagnosis and treatment of co-occurring ADHD and SUD. Read More

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http://dx.doi.org/10.1097/YCO.0000000000000513DOI Listing

Associations between Physical Activity and Chronic Pain Severity in Youth With Chronic Abdominal Pain.

Clin J Pain 2019 Apr 18. Epub 2019 Apr 18.

Children's Mercy Hospital.

Objectives: The present study aimed to: (1) better understand physical activity levels in youth with chronic abdominal pain and (2) investigate the relationship between day-level physical activity related to next day pain intensity to identify any intra-individual heterogeneity.

Methods: Seventy-one youth (M=13.34▒y, SD=2. Read More

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http://dx.doi.org/10.1097/AJP.0000000000000716DOI Listing

Smartphone Apps Targeting Alcohol and Illicit Substance Use: Systematic Search in in Commercial App Stores and Critical Content Analysis.

JMIR Mhealth Uhealth 2019 Apr 22;7(4):e11831. Epub 2019 Apr 22.

Department of Population Health, New York University School of Medicine, New York, NY, United States.

Background: Smartphone apps promise to enhance the reach of evidence-based interventions (cognitive behavior therapy, contingency management and therapeutic education system) for populations with substance use disorders, with minimal disruption to health systems. However, further studies are needed to systematically evaluate smartphone apps targeting alcohol and illicit substances.

Objective: The aim of this study was to evaluate the functionality, aesthetics, and quality of information of free or low-cost apps claiming to target alcohol, benzodiazepine, cocaine, crack/cocaine, crystal methamphetamine, and heroin use using the validated Mobile App Rating Scale (MARS) and critical content analysis. Read More

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http://dx.doi.org/10.2196/11831DOI Listing

Exploring Associations Between the Self-Reported Values, Well-Being, and Health Behaviors of Finnish Citizens: Cross-Sectional Analysis of More Than 100,000 Web-Survey Responses.

JMIR Ment Health 2019 Apr 22;6(4):e12170. Epub 2019 Apr 22.

Smart Health, VTT Technical Research Centre of Finland Ltd, Tampere, Finland.

Background: Understanding the relationship between personal values, well-being, and health-related behavior could facilitate the development of engaging, effective digital interventions for promoting well-being and the healthy lifestyles of citizens. Although the associations between well-being and values have been quite extensively studied, the knowledge about the relationship between health behaviors and values is less comprehensive.

Objective: The aim of this study was to assess retrospectively the associations between self-reported values and commitment to values combined with self-reported well-being and health behaviors from a large cross-sectional dataset. Read More

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http://dx.doi.org/10.2196/12170DOI Listing

PPAR-δ Activation Ameliorates Diabetes-Induced Cognitive Dysfunction by Modulating Integrin-linked Kinase and AMPA Receptor Function.

J Am Coll Nutr 2019 Apr 22:1-10. Epub 2019 Apr 22.

a Department of Drug Discovery and Development, Harrison School of Pharmacy , Auburn University , Auburn , Alabama , USA.

An estimated 9% of the American population experiences type II diabetes mellitus (T2DM) due to diet or genetic predisposition. Recent reports indicate that patients with T2DM are at increased risk for cognitive dysfunctions, as observed in conditions like Alzheimer's disease (AD). In addition, AD is the leading cause of dementia, highlighting the urgency of developing novel therapeutic targets for T2DM-induced cognitive deficits. Read More

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http://dx.doi.org/10.1080/07315724.2019.1598307DOI Listing

Purpose in life and conflict-related neural responses during health decision-making.

Health Psychol 2019 Apr 22. Epub 2019 Apr 22.

Annenberg School for Communication, University of Pennsylvania.

Objective: Having a strong sense of purpose in life is associated with positive health behaviors. However, the processes through which purpose leads to health are unclear. The current study compared neural activity among individuals with higher versus lower purpose while they made health-related decisions in response to messages promoting health behavior change. Read More

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http://dx.doi.org/10.1037/hea0000729DOI Listing

Neural valuation of antidrinking campaigns and risky peer influence in daily life.

Health Psychol 2019 Apr 22. Epub 2019 Apr 22.

Annenberg School for Communication, Marketing Department, The Wharton School, University of Pennsylvania.

Objective: Health behavior is affected by competing sources of influence like media messages and peers. In the context of alcohol consumption, college students are targeted by antidrinking media messages, but tend to have proalcohol conversations with peers. How do humans integrate competing sources of influence on daily behavior? We observed individuals under exposure to antialcohol media messages and proalcohol conversations and tested a "common neural value" account of how contradictory influences are integrated to affect behavior. Read More

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http://dx.doi.org/10.1037/hea0000732DOI Listing

Distress tolerance trajectories following substance use treatment.

J Consult Clin Psychol 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill.

Objective: Distress tolerance (DT), the ability to withstand aversive internal states, represents an important risk factor for substance use relapse and a potential treatment target. Neurobiological research in substance using populations suggests that continued substance use could erode DT, whereas abstinence could bolster it. The current study characterized trajectories of behavioral and self-reported indices of DT and examined the prospective effect of substance use on DT trajectories among those seeking treatment for substance use. Read More

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http://dx.doi.org/10.1037/ccp0000403DOI Listing

Understanding cerebellum in vertebrate neuroethology: From sensing in sharks and electric fish to motor sequences in movement and birdsong.

Behav Neurosci 2019 Apr 22. Epub 2019 Apr 22.

Department of Neuroscience and Zuckerman Institute, Columbia University.

The elaborate structure of the cerebellum has been long known, although its contribution to a remarkable diversity of behavior is only recently appreciated. Taking an evolutionary perspective, we consider the wider function of the cerebellum based on insight from the function of so-called cerebellum-like structures. Cerebellum-like structures cancel the effects of self-stimulation, a function that has been well characterized in both elasmobranch and weakly electric fish. Read More

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http://dx.doi.org/10.1037/bne0000317DOI Listing
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