2,305,111 results match your criteria Behavioral sleep medicine[Journal]


Effects of Light Treatment on Sleep, Cognition, Mood, and Behavior in Alzheimer's Disease: A Systematic Review.

Dement Geriatr Cogn Disord 2018 Dec 11;46(5-6):371-384. Epub 2018 Dec 11.

Department of Biomedical and NeuroMotor Sciences, Functional MR Unit, University of Bologna, Bologna,

Background: Bright light treatment is a therapeutic intervention mainly used to treat sleep and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of studies also focused on the effect on cognition and behavior. Conflicting findings are reported in the literature, and no definite conclusions have been drawn about its specific therapeutic effect. Read More

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December 2018

Cortisol Stress Reactivity to the Trier Social Stress Test in Obese Adults.

Obes Facts 2018 Dec 11;11(6):491-500. Epub 2018 Dec 11.

Objective: Approximately 600 million adults worldwide suffer from obesity. In addition to individual's eating behavior and lack of physical activity in the development of obesity and overweight, psychosocial stress as well as hormonal stress reactivity must also be considered as important contributing factors. In the current study we compared the cortisol stress response pathway in a psychosocial stress induction (Trier Social Stress Test; TSST) with obese individuals and normal-weight controls. Read More

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December 2018
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Disclosing odd symmetry, strain driven magnetic response of Co on Pt/PMN-PT (011).

J Phys Condens Matter 2018 Dec 11. Epub 2018 Dec 11.

ALBA Synchrotron Light Source, Cerdanyola del Valles, SPAIN.

An odd-symmetry magnetic response of multiferroic composites comprising ultrathin Co layers on Pt electrode (20 nm) on PMN-PT (011) piezoelectric substrates is observed upon electrical poling of the PMN-PT substrates: The magnetic easy axis of the Co rotates by 90 degrees in-plane between oppositely poled ferroelectric states, mimicking the signature of a surface polarization charge driven effect, which however can be excluded from the presence of the thick Pt interlayer. The origin for this unexpected behavior is as an odd symmetry piezoelectric response of the PMN-PT substrate, as indicated by X-ray diffraction with applied poling, in combination with conventional magnetoelastic coupling. Ferroelectric characterization reveals corresponding features, possibly related to an unswitchable polarization component. Read More

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December 2018

Six-year outcome for children with ODD or CD treated with the coping power program.

Psychiatry Res 2018 Dec 4;271:454-458. Epub 2018 Dec 4.

The University of Alabama, Tuscaloosa, AL USA.

Children with severe aggressive behavioral problems are one of the groups most frequently referred to mental health clinics, and they engage in behaviors that put them at risk for substance use problems and a host of other negative outcomes. The present study aimed to assess the long-term outcome (six-year follow up) of the Coping Power Program delivered in a mental health hospital for children with behavioral disorders. We recruited one hundred and twenty children (mean age = 9. Read More

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December 2018

Differences in perceptions of e-cigarettes across daily and non-daily users.

Addict Behav 2018 Dec 5;90:415-420. Epub 2018 Dec 5.

Department of Psychology, University of Houston, Houston, TX, United States; Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Health Institute, University of Houston, Houston, TX, United States. Electronic address:

Objective: E-cigarette use has increased significantly over the past decade. Among the growing population of e-cigarette users, several pattern-based subgroups have emerged, including daily and non-daily users. Daily users are at greater risk for experiencing negative health consequences from use. Read More

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December 2018
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Brief reaching training with "sticky mittens" in preterm infants: Randomized controlled trial.

Hum Mov Sci 2018 Dec 8;63:138-147. Epub 2018 Dec 8.

Physical Therapy Section, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. Electronic address:

Objective: To examine whether a brief reaching training with sticky mittens was effective to improve reaching behavior in newly reaching preterm infants.

Methods: In this randomized controlled trial, twenty four 5-month-old (±16-week-old corrected age) preterm infants were randomly allocated into experimental or control groups. Infants were assessed three times in a single session: pretraining (immediately before training), posttraining (immediately after training), and retention (4 min after the posttraining). Read More

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December 2018

Abuse disclosures of youth with problem sexualized behaviors and trauma symptomology.

Child Abuse Negl 2018 Dec 8;88:201-211. Epub 2018 Dec 8.

Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States; The Ohio State University College of Medicine, Department of Pediatrics, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States. Electronic address:

Background: The majority of youth with problem sexualized behaviors (PSB) have substantiated experiences of abuse or exposures to violence (Silovsky & Niec, 2002). Little is known about specific abuse experiences that may differentiate youth with PSB from those without. Few studies have examined the types of abuse associated with post-traumatic stress symptomology. Read More

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December 2018
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A roadmap towards a functional paradigm for learning & memory in plants.

J Plant Physiol 2018 Nov 8;232:209-215. Epub 2018 Nov 8.

Institute of Applied Biosciences, Center for Research & Technology (CERTH), Thessaloniki, Greece.

In plants, the acquisition, processing and storage of empirical information can result in the modification of their behavior according to the nature of the stimulus, and yet this area of research remained relatively understudied until recently. As the body of evidence supporting the inclusion of plants among the higher organisms demonstrating the adaptations to accomplish these tasks keeps increasing, the resistance by traditional botanists and agricultural scientists, who were at first cautious in allowing the application of animal models onto plant physiology and development, subsides. However, the debate retains much of its heat, a good part of it originating from the controversial use of nervous system terms to describe plant processes. Read More

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November 2018

Adsorption and mechanistic study for phosphate removal by magnetic FeO-doped spent FCC catalysts adsorbent.

Chemosphere 2018 Nov 21;219:183-190. Epub 2018 Nov 21.

State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai, 200237, China.

The waste materials utilization has attained increasing attention due to the generation of a large number of spent materials. In the current study, a practical magnetic adsorbent (FeO-doped spent Fluid Catalytic Cracking catalysts, abbreviated as FCC@(Fe)-O) was prepared, liable to be separated. The batch experiments were employed to investigate the phosphate removal behavior. Read More

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November 2018

Cardiovascular toxicity and anxiety-like behavior induced by deltamethrin in zebrafish (Danio rerio) larvae.

Chemosphere 2018 Dec 5;219:155-164. Epub 2018 Dec 5.

State Key Laboratory of Medicinal Chemical Biology, The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin, 300071, China. Electronic address:

Deltamethrin is widely used because of its low toxicity and high efficiency. Although its potential toxicity has been reported, its effects on cardiovascular system and motor behavior and its underlying mechanisms have remained unclear. In this study, the effects of deltamethrin on the development, cardiovascular system and motor behavior of zebrafish larvae and their possible mechanisms were evaluated using the transgenic zebrafish Tg (kdrl:mCherry) and Tg(myl7:GFP). Read More

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December 2018

Green synthesis of reduced graphene oxide using bagasse and its application in dye removal: A waste-to-resource supply chain.

Chemosphere 2018 Dec 3;219:148-154. Epub 2018 Dec 3.

School of Environmental Science and Engineering, Fujian Normal University, Fuzhou 350007, Fujian Province, China. Electronic address:

Graphene is usually synthesized through deoxygenation of graphene oxide (GO) by hydrazine which functions as a reducing agent, but the production of graphene via this method suffers a high cost and is often regarded to be not environmental-friendly. In this work, we developed a simple and efficient method for the green reduction of GO to reduced graphene oxide (rGO) dispersed on sugarcane bagasse derived from rGO/bagasse material. The rGO/bagasse was characterized by Scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, Thermogravimetric analysis, X-ray photoelectron spectroscopy and X-ray diffraction analysis. Read More

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December 2018

Children engage in competitive altruism.

J Exp Child Psychol 2018 Dec 8;179:176-189. Epub 2018 Dec 8.

Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA.

Humans cultivate their reputations as good cooperators, sometimes even competing with group mates, to appear most cooperative to individuals during the process of selecting partners. To investigate the ontogenetic origins of such "competitive altruism," we presented 5- and 8-year-old children with a dyadic sharing game in which both children simultaneously decided how many rewards to share with each other. The children were either observed by a third-person peer or not. Read More

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December 2018

Topological design, permeability and mechanical behavior of additively manufactured functionally graded porous metallic biomaterials.

Acta Biomater 2018 Dec 8. Epub 2018 Dec 8.

Department of Biomechanical Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.

Recent advances in additive manufacturing (AM) have enabled the fabrication of functionally graded porous biomaterials (FGPBs) for application as orthopedic implants and bone substitutes. Here, we present a step-wise topological design of FGPB based on diamond unit cells to mimic the structure of the femoral diaphysis. The FGPB was manufactured from Ti-6Al-4V powder using the selective laser melting (SLM) technique. Read More

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December 2018
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Explaining consumers' intentions towards purchasing green food in Qingdao, China: The amendment and extension of the theory of planned behavior.

Appetite 2018 Dec 8. Epub 2018 Dec 8.

Department of Organic Food Quality and Food Culture, Faculty of Organic Agricultural Sciences, University of Kassel, Nordbahnhofstrasse 1A, 37213, Witzenhausen, Germany.

This study aims to investigate consumers' green food purchase intentions using a survey conducted in Qingdao, Shandong Province, China. Based on the Theory of Planned Behavior (TPB), it models the influences of Chinese culture and consumer characteristics towards purchasing green food products. According to TPB, the behavioral intention is determined by attitude, subjective norms and perceived behavioral control, whereas subjective norms vary according to differences in cultural systems. Read More

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December 2018

Distinct roles of GluA2-lacking AMPA receptor expression in dopamine D1 or D2 receptor neurons in animal behavior.

Neuroscience 2018 Dec 8. Epub 2018 Dec 8.

Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, United States. Electronic address:

Dopaminergic signaling in the central nervous system regulates several aspects of animal behavior. In the dopaminergic circuits, there are two classes of neurons that can be differentiated by their expression of dopamine receptors, D1 or D2 receptors (D1Rs or D2Rs). Notably, Ca-permeable GluA2-lacking glutamate AMPA receptors (CP-AMPARs) are important for gating synaptic plasticity and gene expression in neurons, and their expression particularly in the striatum affects various forms of animal behavior. Read More

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December 2018

Sex differences in the temporal neuromolecular and synaptogenic effects of the rapid-acting antidepressant drug ketamine in the mouse brain.

Neuroscience 2018 Dec 8. Epub 2018 Dec 8.

Department of Biology & Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton, Dayton, Ohio, USA. Electronic address:

Preclinical evidence suggests that ketamine's rapid and sustained antidepressant actions are due to the induction of synaptogenesis in the medial prefrontal cortex (mPFC) and the hippocampus (HIPP), two brain regions implicated in the pathophysiology of major depression. However, research on the neurobiological effects of ketamine has focused almost exclusively on males. Findings from our group and others indicate that female rodents are more reactive to ketamine's antidepressant effects, since they respond to lower doses in antidepressant-predictive behavioral models. Read More

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December 2018

Hyperexcitability of hippocampal CA1 pyramidal neurons in male offspring of a rat model of autism spectrum disorder (ASD) induced by prenatal exposure to valproic acid: a possible involvement of Ih channel current.

Brain Res 2018 Dec 8. Epub 2018 Dec 8.

Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Autism spectrum disorder (ASD) is a common neuropsychiatric disorder, which is characterized by impairment in social interaction and cognitive behaviors. However, there is not much electrophysiological data available on alterations of neuronal excitability in autism. Here, we assessed the pattern of neuronal excitability and the possible contribution of Ih current to the altered excitability of hippocampal CA1 pyramidal neurons in a rat model of VPA-induced ASD-like behavior. Read More

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December 2018

Clinicopathologic and prognostic significance of MKK4 and MKK7 in resectable pancreatic ductal adenocarcinoma.

Hum Pathol 2018 Dec 8. Epub 2018 Dec 8.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100730, China. Electronic address:

Mitogen-activated protein kinase kinase 4 (MKK4) and mitogen-activated protein kinase kinase 7 (MKK7) were shown to regulate biological behavior in many malignancies. In pancreatic ductal adenocarcinoma (PDAC), it remains controversial whether MKK4 and MKK7 have pro-oncogenic or tumor-suppressive activities. Furthermore, their clinicopathologic and prognostic implications are unknown. Read More

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December 2018

Strain State Dependent Anisotropic Viscoelasticity of Tendon-to-Bone Insertion.

Math Biosci 2018 Dec 8. Epub 2018 Dec 8.

Mechanical and Aerospace Engineering Department, North Carolina State University, R3158 Engineering Building 3, Campus Box 7910, 911 Oval Drive, Raleigh, NC 27695. Electronic address:

Tendon-to-bone insertion tissues may be considered as functionally-graded connective tissues, providing a gradual transition from soft tendon to hard bone tissue, and functioning to alleviate stress concentrations at the junction of these tissues. The tendon-to-bone insertion tissues demonstrate pronounced viscoelastic behavior, like many other biological tissues, and are designed by the nature to alleviate stress at physiological load rates and strains states. In this paper we present experimental data showing that under biaxial tension tendon-to-bone insertion demonstrates rate-dependent behavior and that stress-strain curves for the in-plane components of stress and strain become less steep when strain rate is increased, contrary to a typical viscoelastic behavior, where the opposite trend is observed. Read More

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December 2018

Microglia in the developing prefrontal cortex of rats show dynamic changes following neonatal disconnection of the ventral hippocampus.

Neuropharmacology 2018 Dec 8. Epub 2018 Dec 8.

Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Québec, Canada. Electronic address:

Impaired ventral hippocampal (VH)-prefrontal cortex (PFC) connectivity is implicated in many cognitive and behavioral disorders. Excitotoxic neonatal VH (nVH) lesion in rat pups has been shown to induce synaptic pruning in the PFC as well as behavioral changes of relevance to developmental neuropsychiatric disorders. In the current study, we hypothesized that microglia, immune cells required for proper brain development and plasticity, may play a role in the development of abnormal behaviors in the nVH-lesioned animals. Read More

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December 2018
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Microbiota modulation by eating patterns and diet composition: impact on food intake.

Am J Physiol Regul Integr Comp Physiol 2018 Dec 19;315(6):R1254-R1260. Epub 2018 Sep 19.

Foods and Nutrition, University of Georgia , Athens, Georgia.

There is accumulating evidence that the gut microbiota and its composition dynamics play a crucial role in regulating the host physiological functions and behavior. Diet composition is the primary modulator of bacterial richness and abundance in the gastrointestinal (GI) tract. Macronutrient (fat, sugar, and protein) and fiber contents are especially important in determining microbiota composition and its effect on health outcomes and behavior. Read More

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December 2018
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Elevated resting blood pressure augments autonomic imbalance in posttraumatic stress disorder.

Am J Physiol Regul Integr Comp Physiol 2018 Dec 10;315(6):R1272-R1280. Epub 2018 Oct 10.

Renal Division, Department of Medicine, Emory University School of Medicine , Atlanta, Georgia.

Posttraumatic stress disorder (PTSD) is characterized by increased sympathetic nervous system (SNS) activity, blunted parasympathetic nervous system (PNS) activity, and impaired baroreflex sensitivity (BRS), which contribute to accelerated cardiovascular disease. Patients with PTSD also have chronic stress-related elevations in resting blood pressure (BP), often in the prehypertensive range; yet, it is unclear if elevated resting blood pressure (ERBP) augments these autonomic derangements in PTSD. We hypothesized that compared with normotensive PTSD (N-PTSD), those with ERBP (E-PTSD) have further increased SNS, decreased PNS activity, and impaired BRS at rest and exaggerated SNS reactivity, PNS withdrawal, and pressor responses during stress. Read More

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December 2018

A clay-based formulation of the herbicide imazaquin containing exclusively the biologically active enantiomer.

Pest Manag Sci 2018 Dec 10. Epub 2018 Dec 10.

Instituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS, CSIC), Avenida Reina Mercedes 10, 41012 Sevilla, Spain.

Background: Imazaquin is a chiral herbicide which displays high mobility in soils. Like other imidazolinones, imazaquin is available for use only as racemic mixture of its enantiomers. In this work, several clay materials were assayed as adsorbents of imazaquin, and then the most suitable material was selected to prepare a clay-based slow release imazaquin nanoformulation containing exclusively the biologically active R-enantiomer. Read More

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December 2018

The role of sleeping sites in the predator-prey dynamics of leopards and olive baboons.

Am J Primatol 2018 Dec;80(12):e22932

Department of Anthropology, University of California, Davis, California.

Predation is widely recognized as an important selective pressure on prey animals such as baboons (Papio spp.), which face high leopard (Panthera pardus) predation risk, particularly at night. Baboons regularly sleep on cliff faces and in trees at night, ostensibly to avoid such predators. Read More

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December 2018
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Diel and infradian (7-day) activity rhythms in Mexican spider monkeys (Ateles geoffroyi) kept with and without visitor contact.

Am J Primatol 2018 Dec;80(12):e22933

Department of Animal Physiology, Institute for Zoology, University of Tübingen, Tübingen, Germany.

Diel activity rhythms in mammals are regulated by an endogenous (circadian) timing system which is synchronized by environmental 24-hr periodicities called zeitgebers. Additional direct responses to stochastic environmental factors ensure the fine-tuning to the actual situation and may mask the circadian time course. Following an observational study on behavioral effects of visitor activities in a group of spider monkeys (Ateles geoffroyi) kept free-ranging on a small island of Lake Catemaco, Veracruz, Mexico, we analyzed the effect of weekly varying numbers of visiting tourist boats on the monkeys' diel activity rhythm. Read More

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December 2018

Genotype and phenotype correlations for SHANK3 de novo mutations in neurodevelopmental disorders.

Am J Med Genet A 2018 Dec 9. Epub 2018 Dec 9.

Center for Medical Genetics & Hunan Provincial Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.

SHANK3 has been identified as the causative gene of 22q13.3 microdeletion syndrome phenotype. De novo mutations (DNMs) of SHANK3 were subsequently identified in patients with several neurodevelopmental disorders, including autism spectrum disorders (ASDs), schizophrenia (SCZ), a Rett syndrome-like phenotype, and intellectual disability (ID). Read More

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December 2018
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Living 3,4-(Co)Polymerization of Isoprene/Myrcene and One-Pot Synthesis of Polyisoprene Blend Catalyzed by Binuclear Rare Earth Complexes Bearing the Bridged Amidinate Ligand.

Chemistry 2018 Dec 7. Epub 2018 Dec 7.

Fudan University, Department of Chemistry, No.2005 Songhu Road, Yangpu District,, 200438, Shanghai, CHINA.

Mononuclear amidinate yttrium complex C₄H₉C(NR)₂Y(o-CH₂C₆H₄NMe₂)₂ (R = 2,6-iPr₂C₆H₃) and a series of binuclear rare-earth-metal complexes bearing a bridged amidinate ligand [(RN)₂C(CH₂)₄C(NR)₂][Ln(CH₂C₆H₄(o-NMe₂))₂]₂(R = 2,6-iPr₂C₆H₃, Ln = Y, Lu, Sc) were synthesized and fully characterized. The catalytic behavior of these complexes for (co)polymerization of conjugated dienes such as isoprene and myrcene in the presence of cocatalyst [Ph₃C][B(C₆F₅)₄] was investigated. These catalytic systems show impressive high activity and 3,4 regio-selectivity in livingness fashion. Read More

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December 2018

Predictors of hypomanic and/or manic switch among patients who initially diagnosed unipolar major depression during acute phase antidepressants treatment.

Psychiatry Clin Neurosci 2018 Dec 9. Epub 2018 Dec 9.

Department of Health Promotion of Human Behavior and Clinical Epidemiology, Kyoto University Graduate School of Medicine / School of Public Health.

Most patients with bipolar disorder have depressive onset polarity. There is, however, very few studies investigating predictors of hypomanic and/or manic change for patients with major depression in Japan. We preliminary explored predictors of hypomanic and/or manic switch during acute phase antidepressants treatment by using the data of the SUND trial that is a multi-center randomized controlled clinical trial. Read More

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December 2018

Brain glutamate, GABA, and glutamine levels and associations with recent drinking in treatment-naïve individuals with Alcohol Use Disorder versus light drinkers.

Alcohol Clin Exp Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry and Behavioral Sciences.

Background: Proton Magnetic Resonance Spectroscopy ( H-MRS) studies have demonstrated abnormal levels of a variety of neurometabolites in inpatients/outpatients with Alcohol Use Disorder (AUD) following acute alcohol withdrawal relative to healthy controls. In contrast, few studies have compared neurometabolite levels between less severe, treatment-naïve AUD individuals and light drinkers or related them to recent alcohol consumption. The present study compared neurometabolite levels between treatment-naïve AUD and LD individuals. Read More

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December 2018

Patterns of infiltration and local recurrences of various types of cutaneous sarcomas following three-dimensional histology.

J Dtsch Dermatol Ges 2018 Dec;16(12):1434-1442

Department of Dermatology, Eberhardt Karls University, Tübingen Germany.

Background: Cutaneous sarcomas are rare and characterized by pathogenetic heterogeneity. Knowledge about local infiltration patterns and recurrence rates may be useful in improving patient care and outcomes. The objective of the present study was to compare these two characteristics in sarcomas that had been treated using the identical surgical procedure. Read More

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December 2018
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Multicomponent analysis of T relaxation in bovine articular cartilage at low magnetic fields.

Magn Reson Med 2018 Dec 10. Epub 2018 Dec 10.

Ilmenau University of Technology, Ilmenau, Germany.

Purpose: The multi-exponential character of T relaxation in bovine articular cartilage was investigated at low magnetic fields below 0.5 T. The ultimate aim was to identify a parameter based on the T relaxation time distribution as a biomarker to biochemical features of osteoarthritis. Read More

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December 2018

Aerodigestive and communicative behaviors in anencephalic and hydranencephalic infants.

Birth Defects Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Linguistics, University of British Columbia, Vancouver, Canada.

The aerodigestive and communicative behaviors of anencephalic and hydranencephalic patients are assessed from literature sources and are compared with documented neural structures present in the brainstem, subcortical, and cortical regions of the brain. Much of the data analyzed corroborate previous neurological studies, which focus on central pattern generators and development in model organisms. However, findings suggest that further research is necessary to determine which components of these systems support these behaviors. Read More

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December 2018

Management of persistent juvenile angiofibroma after endoscopic resection: Analysis of a single institution series of 74 patients.

Head Neck 2018 Dec 10. Epub 2018 Dec 10.

Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Brescia, Italy.

Background: Management of persistent juvenile angiofibroma (pJA) after transnasal endoscopic resection is controversial. To better understand its behavior, optimize treatment, and minimize morbidity, we report our experience in pJA focusing on follow-up strategies and disease progression.

Methods: A retrospective review of clinical records of all JA cases treated with endoscopic surgery at the Unit of Otorhinolaryngology of the University of Brescia between January 1994 and October 2015 was performed. Read More

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December 2018
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Extreme adaptation in caves.

Anat Rec (Hoboken) 2018 Dec 11. Epub 2018 Dec 11.

Department of Biological Sciences, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, AL 35899.

Cave adaptation leads to unique anatomical specializations in many taxonomic groups. As the role of vision is reduced or disappears in a subterranean environment, other specializations arise to allow the organism to successfully detect and interact with their environment. A suite of unique, convergent phenotypes associated with subterranean adaptation has emerged (termed troglomorphy), with reduction or loss of pigmentation and eyes being the most conspicuous. Read More

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December 2018

Oleoylethanolamide: A novel pharmaceutical agent in the management of obesity-an updated review.

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Nutrition, Nutrition Research Center, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.

Obesity as a multifactorial disorder has been shown a dramatically growing trend recently. Besides genetic and environmental factors, dysregulation of the endocannabinoid system tone is involved in the pathogenesis of obesity. This study reviewed the potential efficacy of Oleoylethanolamide (OEA) as an endocannabinoid-like compound in the energy homeostasis and appetite control in people with obesity. Read More

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December 2018
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Relative Cost Effectiveness of In-Person and Internet Interventions for Relationship Distress.

Fam Process 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychology, University of Miami, Coral Gables, FL.

While the efficacy of couple therapy has been repeatedly demonstrated, most distressed couples do not seek treatment. To improve reach and overcome barriers to therapy, Integrative Behavioral Couple Therapy (IBCT) was translated into a web-based program, OurRelationship (OR). While both IBCT and OR have been shown to improve relationship and individual functioning, the goal of the present study was to compare the relative cost effectiveness of these two treatment modalities. Read More

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December 2018

Four structural variants associated with human-directed sociability in dogs are not found in tame red foxes (Vulpes vulpes).

Anim Genet 2018 Dec 10. Epub 2018 Dec 10.

Department of Animal Science, College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

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December 2018

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells.

Eur J Immunol 2018 Dec 7. Epub 2018 Dec 7.

Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Under homeostatic conditions, dendritic cells (DCs) continuously patrol the intestinal lamina propria. Upon antigen encounter, DCs initiate C-C motif chemokine receptor 7 (CCR7) expression and migrate into lymph nodes to direct T cell activation and differentiation. The mechanistic underpinnings of DC migration from the tissues to lymph nodes have been largely elucidated, contributing greatly to our understanding of DC functionality and intestinal immunity. Read More

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December 2018

The Nomological Network of a Behavioral Distress Tolerance Task in Veterans.

J Trauma Stress 2018 Dec 11. Epub 2018 Dec 11.

Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.

There is a relative lack of research on distress tolerance (DT) in veteran samples. The aims of the study were to (a) evaluate convergent and discriminant validity of a behavioral measure of DT compared to theoretically similar (i.e. Read More

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December 2018

Microglial cell activation and senescence are characteristic of the pathology FXTAS.

Mov Disord 2018 Dec 10. Epub 2018 Dec 10.

MIND Institute, UC Davis Medical Center, Sacramento, California, USA.

Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with premutation alleles of the FMR1 gene. Expansions of more than 200 CGG repeats give rise to fragile X syndrome, the most common inherited form of cognitive impairment. Fragile X-associated tremor/ataxia syndrome is characterized by cerebellar tremor and ataxia, and the presence of ubiquitin-positive inclusions in neurons and astrocytes. Read More

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December 2018
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From nodes to networks: How methods for defining nodes influence inferences regarding network interactions.

Hum Brain Mapp 2018 Dec 7. Epub 2018 Dec 7.

Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, Florida.

Functional connectivity (FC) analysis of fMRI data typically rests on prior identification of network nodes from activation profiles. We compared Activation Likelihood Estimate (ALE) and the Experimentally Derived Estimate (EDE) approaches to network node identification and functional inference for both verbal and visual forms of working memory. ALE arrives at canonical activation maxima that are assumed to reliably represent peaks of brain activity underlying a psychological process (e. Read More

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December 2018

Ting-Kai Li: In Memoriam.

Alcohol Clin Exp Res 2018 Dec 10. Epub 2018 Dec 10.

Indiana University School of Medicine, Dept. of Biochemistry and Molecular Biology, 635 Barnhill Drive, MS4063, Indianapolis, Indiana.

Ting-Kai (T-K) Li, MD died on November 18, 2018, just five days after his 84 birthday. T-K had a wonderful and distinguished academic and public service career, spanning almost five decades. Born in Nanjing, China, T-K fled with his family to South Africa during World War II, while a young boy. Read More

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December 2018

The Fyn kinase inhibitor, AZD0530, suppresses mouse alcohol self-administration and seeking.

Addict Biol 2018 Dec 7. Epub 2018 Dec 7.

Department of Neurology, University of California San Francisco, San Francisco, California.

Fyn is a member of the Src family of protein tyrosine kinases (PTKs) that plays an important role not only in normal synaptic functions but also in brain pathologies including alcohol use disorder. We previously reported that repeated cycles of binge drinking and withdrawal activate Fyn in the dorsomedial striatum (DMS) of rodents, and that Fyn signaling in the DMS contributes to rat alcohol intake and relapse. Here, we used AZD0530, a CNS penetrable inhibitor of Src PTKs developed for the treatment of Alzheimer disease and cancer and tested its efficacy to suppress alcohol-dependent molecular and behavioral effects. Read More

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December 2018

Pathways of Superoxide Decay in Oxygen Reduction Reaction on Carbon-based Catalysts Evidenced by Theoretical Calculations.

ChemSusChem 2018 Dec 11. Epub 2018 Dec 11.

Guangzhou University, School of Chemistry and Chemical Engineering, 230 Wai Huan Xi Road,Guangzhou Higher Education Mega Center, 510006, Guangzhou, CHINA.

The superoxide decay behavior is evaluated by contrastive potential energy surface analyses from theoretical calculations. The presence of carbon surface enhances the superoxide decay via disproportionation instead of electroreduction, which is a non-electrochemical reaction impeding the increase in energy efficiency for relevant energy conversion applications. Nitrogen doping in carbon effectively retards the disproportionation by influencing the oxygen stretching vibration and changing the proton coupled electron transfer trend. Read More

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December 2018

Nurses' organizational communication satisfaction, emotional labor, and prosocial service behavior: A cross-sectional study.

Nurs Health Sci 2018 Dec 10. Epub 2018 Dec 10.

Red Cross College of Nursing, Chung-Ang University, Seoul, Korea.

In this study, we investigated nurses' organizational communication satisfaction and emotional labor in an attempt to identify the factors that influence nurses' prosocial service behavior in Korea. A cross-sectional study was conducted on 145 nurses at two Korean tertiary hospitals in 2017. Most participants (89%) were female, and the mean age was 28. Read More

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December 2018

Determining the motivations of family members to undertake cardiopulmonary resuscitation training through grounded theory.

J Adv Nurs 2018 Dec 10. Epub 2018 Dec 10.

Capital Medical University, School of Nursing.

Aims: To explore the motivation of family members of patients at high risk for sudden cardiac death for undertaking cardiopulmonary resuscitation (CPR) training.

Background: Home cardiac arrests are associated with poor outcomes because few family members learn CPR. Little is known about factors that motivate family members to participate in CPR training. Read More

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December 2018

Ultra high performance liquid chromatography with tandem mass spectrometry method for determination of four compounds in rat plasma after oral administration of Xanthii fructus and stir-fried Xanthii fructus extracts.

Biomed Chromatogr 2018 Dec 9:e4464. Epub 2018 Dec 9.

Engineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, China.

Xanthii fructus (XF), the fruit of Xanthium sibiricum Patr. is a traditional Chinese materia medica commonly used to treat allergic rhinitis (AR) and other rhinitis diseases. To uncover the mechanism of stir frying process and its effect on pharmacokinetic behavior of active compounds in model rats, four active compounds including chlorogenic acid, 4-caffeoylquinic acid, 1,5-O-dicaffeoylquinic acid and apigenin were selected based on previous spectrum-effect experiments. Read More

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December 2018
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