2,258,089 results match your criteria Behavior Modification[Journal]


A coordinate-based meta-analysis comparing brain activation between ADHD and total sleep deprivation.

Sleep 2018 Dec 12. Epub 2018 Dec 12.

Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Study Objectives: Sleep disruption is common in attention-deficit-hyperactivity-disorder (ADHD). Likewise, deficits in attention are a hallmark of sleep deprivation in healthy individuals. Whether ADHD and sleep deprivation modulate common, or disparate, neural systems is unknown. Read More

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December 2018

Factors that can influence the survival rates of coral snakes (Micrurus corallinus) for antivenom production.

J Anim Sci 2018 Dec 12. Epub 2018 Dec 12.

Laboratório de Herpetologia do Instituto Butantan, Av. Vital Brazil, São Paulo - Brasil.

Envenoming and deaths resulting from snakebites are a particularly important public health problem in rural tropical areas of Africa, Asia, Latin America and New Guinea. In 2015 The Lancet highlighted snake-bite envenoming as a neglected tropical disease and urged the world to increase antivenom production. In Brazil around 20,000 snakebites occur per year affecting mostly agricultural workers and children, of which 1% are caused by coral snakes (Micrurus sp). Read More

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December 2018

Maximum Time Between Tests: A Digital Biomarker to Detect Therapy Compliance and Assess Schedule Quality in Measurement-Based eHealth Systems for Alcohol Use Disorder.

Alcohol Alcohol 2018 Dec 12. Epub 2018 Dec 12.

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

Aim: To evaluate, in a breathalyzer-based eHealth system, whether the time-based digital biomarker 'maximum time between tests' (MTBT) brings valuable information on alcohol consumption patterns as confirmed by correlation with blood phosphatidyl ethanol (PEth), serum carbohydrate deficient transferrin (CDT) and timeline follow-back data.

Method: Data on 54 patients in follow-up for treatment of alcohol use disorder were analysed.

Results: The model of weekly averages of 24-log transformed MTBT adequately described timeline follow-back data (P  <  0. Read More

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December 2018

Electrical transport and gas sensing characteristics of dielectrophoretically aligned MBE grown catalyst free InAs nanowires.

Nanotechnology 2018 Dec 12. Epub 2018 Dec 12.

DRDO Solid State Physics Laboratory, Lucknow Road, Timarpur, Delhi, Delhi, 110054, INDIA.

In this report, the precise alignment of catalyst free InAs nanowires (NWs) on pre-patterned Au microelectrodes by dielectrophoresis (DEP) technique for gas sensing applications is presented. The catalyst free InAs NWs have been grown on Si (111) substrate by molecular beam epitaxy (MBE) technique. The effect of dispersing solvents, electrode geometries and gaps, magnitude, frequency and duration of applied voltage etc. Read More

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December 2018

Effect of the anchoring strength on the phase behaviour of discotic liquid crystals under face-on confinement.

J Phys Condens Matter 2018 Dec 12. Epub 2018 Dec 12.

Universidad Nacional Autonoma de Mexico Instituto de Investigaciones en Materiales, Mexico D.F., Coyoacan, MEXICO.

In this study we have performed molecular dynamics simulations to study a Gay-Berne discotic fluid confined in a slab geometry for a fixed confinement length. Four different anchoring strengths with a homeotropic (face-on) configuration were studied. We found that changing the anchoring strength changes the normal component of the stress tensor, which in turn changes de density of the system's bulk. Read More

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December 2018

Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.

Cell Rep 2018 Dec;25(11):3194-3203.e4

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

5-hydroxymethylcytosine (5hmC) is enriched in brain and has been recognized as an important DNA modification. However, the roles of 5hmC and its writers, ten-eleven translocation (Tet) proteins, in stress-induced response have yet to be elucidated. Here, we show that chronic restraint stress (CRS) induced depression-like behavior in mice and resulted in a 5hmC reduction in prefrontal cortex (PFC). Read More

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December 2018

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.

Cell Rep 2018 Dec;25(11):3123-3135.e6

National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu Natal, Durban 4041, South Africa. Electronic address:

Antibodies that bind residue K169 in the V2 region of the HIV-1 envelope correlated with reduced risk of infection in the RV144 vaccine trial but were restricted to two ED-motif-encoding light chain genes. Here, we identify an HIV-infected donor with high-titer V2 peptide-binding antibodies and isolate two antibody lineages (CAP228-16H/19F and CAP228-3D) that mediate potent antibody-dependent cell-mediated cytotoxicity (ADCC). Both lineages use the IGHV5-51 heavy chain germline gene, similar to the RV144 antibody CH58, but one lineage (CAP228-16H/19F) uses a light chain without the ED motif. Read More

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December 2018

Electroluminescence Generation in PbS Quantum Dot Light Emitting Field Effect Transistors with Solid State Gating.

ACS Nano 2018 Dec 12. Epub 2018 Dec 12.

The application of light emitting field effect transistors (LEFET) is an elegant way of combining electrical switching and light emission in a single device architecture instead of two. This allows for a higher degree of miniaturisation and integration in future opto-electronic applications. Here, we report on a LEFET based on lead sulphide quantum dots processed from solution. Read More

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December 2018

Utility of time-lapse photography in studies of seabird ecology.

PLoS One 2018 12;13(12):e0208995. Epub 2018 Dec 12.

School of Environmental Sciences, University of Liverpool, Liverpool, United Kingdom.

Marine ecosystems are heavily influenced by a wide range of human-related impacts, and thus monitoring is essential to preserve and manage these sensitive habitats. Seabirds are considered important bioindicators of the oceans, but accessing breeding populations can be difficult, expensive and time consuming. New technologies have been employed to facilitate data collection on seabirds that can reduce costs and minimize disturbance. Read More

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December 2018
1 Read

Patients who leave Emergency Department without being seen or during treatment in the Lazio Region (Central Italy): Determinants and short term outcomes.

PLoS One 2018 12;13(12):e0208914. Epub 2018 Dec 12.

Department of Epidemiology, Lazio Regional Health Service, Rome, Italy.

Background And Aims: Patients who leave Emergency Department before physician's visit (LWBS) or during treatment (LDT) represent a useful indicator of the emergency care's quality. The profile of patients LWBS was described: they are generally males, young, with lower urgency triage allocation and longer waiting time. They have a greater risk of ED re-admission compared to discharged patients, but effect on hospitalization and mortality are more controversial. Read More

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December 2018

Inferring symmetric and asymmetric interactions between animals and groups from positional data.

PLoS One 2018 12;13(12):e0208202. Epub 2018 Dec 12.

Department of Mathematics and Statistics, University of Western Australia, Nedlands, Perth, WA, Australia.

Interactions between domestic and wild species has become a global problem of growing interest. Global Position Systems (GPS) allow collection of vast records of time series of animal spatial movement, but there is need for developing analytical methods to efficiently use this information to unravel species interactions. This study assesses different methods to infer interactions and their symmetry between individual animals, social groups or species. Read More

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December 2018

Eye blinks are perceived as communicative signals in human face-to-face interaction.

PLoS One 2018 12;13(12):e0208030. Epub 2018 Dec 12.

Language and Cognition Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.

In face-to-face communication, recurring intervals of mutual gaze allow listeners to provide speakers with visual feedback (e.g. nodding). Read More

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December 2018
3 Reads

Age threshold for recommending higher protein intake to prevent age-related muscle weakness: A cross-sectional study in Japan.

PLoS One 2018 12;13(12):e0208169. Epub 2018 Dec 12.

Departments of Health and Social Behavior, School of Public Health, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Although insufficient dietary protein intake is a known risk factor for age-related muscle weakness, the optimal age at which higher protein intake is required to prevent muscle weakness is yet to be determined. Using a population-based panel survey of community-dwelling people aged 50-75 years, this cross-sectional study aimed to find the age threshold at which a higher protein intake is associated with higher muscle strength. We utilized a dataset from the Japanese Study of Aging and Retirement conducted between 2007 and 2011. Read More

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December 2018

Quality and quantity of leaf litter: Both are important for feeding preferences and growth of an aquatic shredder.

PLoS One 2018 12;13(12):e0208272. Epub 2018 Dec 12.

Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, Spain.

The study of leaf litter as a resource for shredders has emerged as a key topic in trophic links in ecology. However, thus far, most studies have emphasized the leaf quality as one of the main determinants of shredder behaviour and growth without simultaneously considering the leaf quantity availability. Nevertheless, the combined effects of leaf quantity and quality on shredder behaviour and growth is particularly crucial to further understand how ecosystem functioning may respond to the increasing flow intermittency due to climate change. Read More

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December 2018

New skeletal material sheds light on the palaeobiology of the Pleistocene marsupial carnivore, Thylacoleo carnifex.

PLoS One 2018 12;13(12):e0208020. Epub 2018 Dec 12.

Ecology and Evolution, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

The extinct marsupial 'lion' Thylacoleo carnifex was Australia's largest mammalian carnivore. Despite being the topic of more discussion than any other extinct Australian marsupial (excepting perhaps the Thylacine), basic aspects of its palaeobiology, including its locomotory repertoire, remain poorly understood. Recent discoveries allowed the first reconstruction of an entire skeleton including the first complete tail and hitherto-unrecognised clavicles. Read More

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December 2018

Evidence for encounter-conditional, area-restricted search in a preliminary study of Colombian blowgun hunters.

PLoS One 2018 12;13(12):e0207633. Epub 2018 Dec 12.

University of California Davis, Department of Anthropology, Davis, CA, United States of America.

Active search for prey is energetically costly, so understanding how foragers optimize search has been central to foraging theory. Some theoretical work has suggested that foragers of randomly distributed prey should search using Lévy flights, while work on area-restricted and intermittent search strategies has demonstrated that foragers can use the information provided by prey encounters to more effectively adapt search direction and velocity. Previous empirical comparisons of these search modes have tended to rely on distribution-level analyses, due to the difficulty of collecting event-level data on encounters linked to the GPS tracks of foragers. Read More

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December 2018

Divergent effects of brief contemplative practices in response to an acute stressor: A randomized controlled trial of brief breath awareness, loving-kindness, gratitude or an attention control practice.

PLoS One 2018 12;13(12):e0207765. Epub 2018 Dec 12.

Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States of America.

Mindfulness practices are increasingly being utilized as a method for cultivating well-being. The term mindfulness is often used as an umbrella for a variety of different practices and many mindfulness-based interventions (MBIs) contain multiple styles of practice. Despite the diversity of practices within MBIs, few studies have investigated whether constituent practices produce specific effects. Read More

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December 2018

Prey of killer whales (Orcinus orca) in Iceland.

PLoS One 2018 12;13(12):e0207287. Epub 2018 Dec 12.

Marine and Freshwater Research Institute, Skúlagata, Reykjavík, Iceland.

Killer whales have a cosmopolitan distribution and as a species are generalists, feeding on a variety of prey. However, local populations tend to specialise on specific prey types. In Icelandic waters, killer whales are generally associated with herring and, thus, have been presumed to be herring specialists. Read More

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December 2018

Susceptibility and resilience to cyber threat: Findings from a scenario decision program to measure secure and insecure computing behavior.

PLoS One 2018 12;13(12):e0207408. Epub 2018 Dec 12.

Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, United States of America.

Interest in the individual differences underlying end user computer security behavior has led to the development of a multidisciplinary field of research known as behavioral information security. An important gap in knowledge and the motivation for this research is the development of ways to measure secure and insecure cyber behavior for research and eventually practice. Here we report a study designed to develop a technique for assessing secure and insecure cyber behavior for broad research use. Read More

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December 2018

Application of the ConNECT Framework to Precision Health and Health Disparities.

Nurs Res 2018 Dec 12. Epub 2018 Dec 12.

Professor and Associate Vice Dean of Research, University of South Florida College of Nursing, Tampa, FL Founding Director, Center of Community Alliance for Research Education, Professor, Department of Population Sciences, Beckman Research Institute, City of Hope Medical Center, Duarte, CA Associate Professor, The Ohio State University, College of Nursing, Columbus, OH Department of Health Outcomes and Behavior, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612 Assistant Professor, College of Nursing, University of Utah, Salt Lake City, UT Professor, Department of Psychological Science, University of North Carolina at Charlotte, Charlotte, NC Senior Member, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL Department of Health Disparities Research, MD Anderson Cancer Center, Houston, TX Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute & Department of Oncological Sciences, University of South Florida, College of Medicine, Tampa, FL Assistant Professor, Department of Oncology Sciences, Icahn School of Medicine at Mount Sinai, New York, NY Assistant Professor, Department of Community Health Sciences, Boston University School of Public Health and Department of Social and Behavioral Sciences, and Harvard T.H. Chan School of Public Health, Boston, MA Assistant Professor, Department of Medical Social Sciences and Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, Chicago, IL Associate Professor, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR Staff Scientist, Project Director, Biobehavioral Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA Strategic Director of Health Disparities Research, Behavioral Research Center, American Cancer Society, Atlanta, GA.

Background: An emphasis on precision health (PH) has stimulated precision medicine studies to focus on the interplay of biological, behavioral, and environmental factors with disease risks, treatments, prognoses, and outcomes affecting health disparities. It is imperative, as well, that improving health equity among underserved populations remains central to the efforts and aims of PH.

Objectives: Apply the transdisciplinary ConNECT Framework: A model for advancing behavioral medicine science and practice to foster health equity to PH by integrating a population health agenda for reducing health disparities. Read More

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December 2018

Voluntary wheel running reveals sex specific nociceptive factors in murine experimental autoimmune encephalomyelitis.

Pain 2018 Dec 11. Epub 2018 Dec 11.

Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB, Canada, T6G 2E1.

Multiple Sclerosis (MS) is an inflammatory, neurodegenerative autoimmune disease associated with sensory and motor dysfunction. Although estimates vary, ∼50% of patients with MS experience pain during their disease. The mechanisms underlying the development of pain are not fully understood and no effective treatment for MS related pain is available. Read More

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December 2018

Automated homecage training of mice in a hold-still center-out reach task.

J Neurophysiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Neurobiology and Behavior, Cornell University, United States.

An obstacle to understanding neural mechanisms of movement is the complex, distributed nature of the mammalian motor system. Here we present a novel behavioral paradigm for high-throughput dissection of neural circuits underlying mouse forelimb control. Custom touch-sensing joysticks were used to quantify mouse forelimb trajectories with micron-millisecond spatiotemporal resolution. Read More

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December 2018
1 Read

Poor estimates of motor variability are associated with longer grooved pegboard times for middle-aged and older adults.

J Neurophysiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Integrative Physiology, University of Colorado, United States.

Goal-directed movements that involve greater motor variability are performed with an increased risk that the intended goal will not be achieved. The ability to estimate motor variability during such actions varies across individuals and influences how people decide to move about their environment. The purpose of our study was to identify the decision-making strategies used by middle-aged and older-adults when performing two goal-directed motor tasks and to determine if these strategies were associated with the time to complete the grooved pegboard test. Read More

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December 2018

The transfer function of the rhesus macaque oculomotor system for small-amplitude slow motion trajectories.

J Neurophysiol 2018 Dec 12. Epub 2018 Dec 12.

Werner Reichardt Centre for Integrative Neuroscience, Germany.

Two main types of small eye movements occur during gaze fixation: microsaccades and slow ocular drifts. While microsaccade generation has been relatively well-studied, ocular drift control mechanisms are unknown. Here we explored the degree to which monkey smooth eye movements, on the velocity scale of slow ocular drifts, can be generated systematically. Read More

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December 2018

Phase shifts in high beta and low gamma band local field potentials predict the focus of visual spatial attention.

J Neurophysiol 2018 Dec 12. Epub 2018 Dec 12.

Neuroscience, University of Rochester School of Medicine, United States.

The local field potential (LFP) contains rich information about activity in local neuronal populations. However, it has been challenging to establish direct links between LFP modulations and task-relevant behavior or cognitive processes, such as attention. We sought to determine whether LFP amplitude or phase modulations were predictive of the allocation of visual spatial attention. Read More

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December 2018
1 Read

Markov Chain Modelling of Surfactant Critical Micelle Concentration and Surface Composition.

Langmuir 2018 Dec 12. Epub 2018 Dec 12.

A Markov chain (MC) model has been used to model the following binary surfactant mixtures: linear alkylbenzene sulfonate (LAS4)/octaethylene glycol monododecyl ether (C12E8) at 10oC and 25oC, LAS6/acidic sophorolipid (AS), C12 betaine/C12 maltoside, sodium lauryl ether sulfate (SLES2)/C12E8, and rhamnolipid (R1)/LAS6. The critical micellar concentration and the composition of the adsorbed layer, for each system, can be modelled using the same monomer reactivity ratio values, g1 and g2. This implies that the interactions between the surfactants in the bulk solution and at the interface are the same, within error. Read More

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December 2018

Designing spatially distributed gene regulatory networks to elicit contrasting patterns.

ACS Synth Biol 2018 Dec 12. Epub 2018 Dec 12.

Pattern formation and differential interactions are important for microbial consortia to divide labor and perform complex functions. To obtain further insight into such interactions, we present a computational method for simulating physically separated microbial colonies each implementing different gene regulatory networks. We validate our theory by experimentally demonstrating control over gene expression patterns in a diffusion-mediated lateral inhibition circuit. Read More

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December 2018

Fundamentally Different Distance Dependences of Electron-Transfer Rates for Low and High Driving Forces.

Inorg Chem 2018 Dec 12. Epub 2018 Dec 12.

Department of Chemistry , University of Basel , St. Johanns-Ring 19 , 4056 Basel , Switzerland.

The distance dependences of electron-transfer rates ( k) in three homologous series of donor-bridge-acceptor compounds with reaction free energies (Δ G) of ca. -1.2, -1. Read More

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December 2018

Lasing Supraparticles Self-Assembled from Nanocrystals.

ACS Nano 2018 Dec 12. Epub 2018 Dec 12.

One of the most attractive foreseen commercial applications of semiconductor nanocrystals (NCs) is their use in lasers. Thanks to their high quantum yield, tunable optical properties, photostability and wet-chemical processability, NCs have arisen as promising gain material. Most of these applications, however, rely on incorporation of NCs in lasing cavities separately produced using sophisticated fabrication methods and often difficult to manipulate. Read More

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December 2018

Real-time Mobile Monitoring of the Dynamic Associations Among Motor Activity, Energy, Mood, and Sleep in Adults With Bipolar Disorder.

JAMA Psychiatry 2018 Dec 12. Epub 2018 Dec 12.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Importance: Biologic systems involved in the regulation of motor activity are intricately linked with other homeostatic systems such as sleep, feeding behavior, energy, and mood. Mobile monitoring technology (eg, actigraphy and ecological momentary assessment devices) allows the assessment of these multiple systems in real time. However, most clinical studies of mental disorders that use mobile devices have not focused on the dynamic associations between these systems. Read More

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December 2018

Self-Preferred Initial Position Could Be a Viable Alternative to the Standard Squat Jump Testing Procedure.

J Strength Cond Res 2018 Nov;32(11):3267-3275

Department of Neurophysiology, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.

Petronijevic, MS, Garcia Ramos, A, Mirkov, DM, Jaric, S, Valdevit, Z, and Knezevic, OM. Self-preferred initial position could be a viable alternative to the standard squat jump testing procedure. J Strength Cond Res 32(11): 3267-3275, 2018-The purpose of this study was to compare both the magnitude and reliability of different variables (knee angle, squat depth, jump height [Hmax], maximum force [Fmax], and maximum power [Pmax]) between the standardized squat jump (SJ) and the SJ performed from the self-preferred position. Read More

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November 2018

Reactive oxygen species regulate activity-dependent neuronal plasticity in .

Elife 2018 Dec 12;7. Epub 2018 Dec 12.

Department of Zoology, University of Cambridge, Cambridge, United Kingdom.

Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the nervous system under non-pathological conditions has remained poorly understood. Working with the larval locomotor network, we show that in neurons ROS act as obligate signals required for neuronal activity-dependent structural plasticity, of both pre- and postsynaptic terminals. Read More

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December 2018

The effect of leisure coping on depressive symptoms among individuals with depression: examination of potential confounding effects of physical activity and extraversion.

Psychol Health Med 2018 Dec 12:1-13. Epub 2018 Dec 12.

c School of Public Health , Indiana University , Bloomington , IN , USA.

Clinically significant depression has been consistently identified as a phenomenon directly linked to stress and stress coping. Leisure behavior as purposeful coping strategy (i.e. Read More

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December 2018

Structural and Luminescence Properties of Anthracene- and Biphenyl-Based Lanthanide Bisphosphonate Ester Coordination Polymers.

Inorg Chem 2018 Dec 12. Epub 2018 Dec 12.

Institute of Chemistry and Center for Interdisciplinary Nanostructure Science and Technology , University of Kassel , Heinrich-Plett-Strasse 40 , 34132 Kassel , Germany.

Coordinative networks containing lanthanide ions attached via phosphonate ester functionalities provide remarkable luminescence properties. On the basis of ditopic phosphonic ester ligands with biphenylene and 9,10-anthracenylene bridges, a series of compounds with formal composition {[M(NO)]L} or {[M(NO)](L1)} (L = CHOP; L1 = CHOP) with M = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, and Y have been synthesized, structurally characterized, and the luminescence behavior was explored in the visible and NIR spectral regions, where applicable. In contrast to closely related networks based on biphenyl bisphosphonate esters from previous work, no evidence for ligand-to-metal energy transfer could be observed, despite strong near-infrared emission in some cases. Read More

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December 2018

Squamous cell carcinoma of the tongue in patients older than 45 years.

Braz Oral Res 2018 Dec 6;32:e123. Epub 2018 Dec 6.

Hospital General de México "Eduardo Liceaga", Department of Pathology, México City, México.

This study aims to evaluate the clinicopathological features, TNM status, AJCC staging and behavior of squamous cell carcinoma of the tongue (SCCT) in patients older than 45 years. The files of the Department of Pathology of the Hospital General de México were reviewed and all cases of SCCT in patients older than 45 years were selected. Clinicopathological features, treatment, follow-up, microscopic diagnosis, and IJCC and TNM staging were retrieved. Read More

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December 2018

ANALYSIS OF RISK FACTORS AND POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH CROHN'S DISEASE.

Arq Gastroenterol 2018 Jul-Sep;55(3):252-257

Universidade Estadual Paulista (UNESP), Faculdade de Medicina, Departamento de Cirurgia e Ortopedia, Botucatu, SP, Brasil.

Background: The post-operative complications rate is greater in patients with Crohn's disease than in other abdominal surgeries due to other benign conditions. Prevention and management of such complications are important factors in the care of these patients.

Objective: The objectives of this research are to analyze the rate of postoperative complications and the major risk factors in patients with Crohn's disease. Read More

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February 2018

From anatomy to function: the role of the somatosensory cortex in emotional regulation.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

Mood Disorders Program, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Canada.

 : Since the pioneering work of Penfield and his colleagues in the 1930s, the somatosensory cortex, which is located on the postcentral gyrus, has been known for its central role in processing sensory information from various parts of the body. More recently, a converging body of literature has shown that the somatosensory cortex also plays an important role in each stage of emotional processing, including identification of emotional significance in a stimulus, generation of emotional states, and regulation of emotion. Importantly, studies conducted in individuals suffering from mental disorders associated with abnormal emotional regulation, such as major depression, bipolar disorder, schizophrenia, post-traumatic stress disorder, anxiety and panic disorders, specific phobia, obesity, and obsessive-compulsive disorder, have found structural and functional changes in the somatosensory cortex. Read More

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December 2018

Brazilian guidelines for the management of psychomotor agitation. Part 1. Non-pharmacological approach.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

Comissão de Emergências Psiquiátricas, Associação Brasileira de Psiquiatria (ABP), Rio de Janeiro, RJ, Brazil.

Objective: To present the essential guidelines for non-pharmacological management of patients with psychomotor agitation in Brazil.

Methods: These guidelines were developed based on a systematic review of articles published from 1997 to 2017, retrieved from MEDLINE (PubMed), Cochrane Database of Systematic Review, and SciELO. Other relevant articles identified by searching the reference lists of included studies were also used to develop these guidelines. Read More

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December 2018

Early childhood maltreatment experience and later sexual behavior in Brazilian adults undergoing treatment for substance dependence.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

Departamento de Psiquiatria,Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

Objective: To investigate the prevalence of early childhood maltreatment and associations with later sexual behavior among adult substance users.

Methods: A cross-sectional study enrolled 134 substance dependents who sought outpatient care in São Paulo, Brazil. Childhood trauma prevalence was assessed using the Childhood Trauma Questionnaire (CTQ). Read More

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December 2018

[Insufficient levels of physical activity of adolescents associated with sociodemographic, environmental and school factors].

Cien Saude Colet 2018 Dec;23(12):4277-4288

Centro de Ciências da Saúde e do Esporte, Universidade do Estado de Santa Catarina. R. Paschoal Simoni 358, Coqueiros. 88080-350 Florianópolis SC Brasil.

This study investigated the associations between the level of physical activity with sociodemographic, environmental and academic factors of adolescents. Two thousand five hundred and forty-five adolescents aged between 14 and 18 from Florianópolis and neighboring cities participated in this study. The short version of the International Physical Activity Questionnaire (IPAQ) was used. Read More

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December 2018

Eating patterns and nutrient intake for older people: analysis with different methodological approaches.

Cien Saude Colet 2018 Dec;23(12):4085-4094

Departamento de Bioestatística, Instituto de Biociências de Botucatu, Unesp. Botucatu SP Brasil.

This study aims to analyse the eating patterns and nutrient intake in different eating patterns of elderly persons. This is a cross-sectional study with elderly people from Botucatu, São Paulo state, Brazil. The mean daily nutrient intake of individuals with high adherence to the eating patterns identified by factor analysis was analysed, comparing the intake by analysis of variance. Read More

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December 2018

Voluntary wheel running: patterns and physiological effects in mice.

Braz J Med Biol Res 2018 Dec 10;52(1):e7830. Epub 2018 Dec 10.

Departamento de Bioquímica e Biologia Tecidual, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil.

Exercise can prevent and improve the pathophysiology of diseases and promote healthy aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise may lead to the development of new strategies to enhance quality of life and to counteract chronic diseases. Voluntary wheel running is an interesting model to study the effects of exercise in mice. Read More

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December 2018

Risk behaviors contributing to recent serious unintentional injuries among school-going adolescent boys in Kolkata: Application of zero-inflated count model.

Indian J Public Health 2018 Oct-Dec;62(4):265-270

Post-Graduate Trainee, Department of Community Medicine, Medical College and Hospital, Kolkata, West Bengal, India.

Background: Unintentional injuries have become a major noncommunicable disease burden, especially among the adolescents.

Objective: The current study was conducted to estimate the effect of different aspects of daily activities of adolescence for sustaining serious unintentional injuries in the past 1 year.

Methods: A cross-sectional survey with multistage sampling with validated pretested questionnaire was done among the school-going adolescent boys in Kolkata. Read More

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December 2018

PTEN and SHIP: Impact on lymphatic metastasis in breast cancer.

J Cancer Res Ther 2018 Dec;14(Supplement):S937-S941

Department of Breast Surgery, Affliated Hospital of Taishan Medical University, Tai'an, China.

Lymph node metastasis is the most common form of metastasis in breast cancer and a crucial indicator influencing breast cancer treatment results. The biological process of lymph node metastasis involves deficiency and mutation of tumor suppressor genes. PTEN and SHIP are critical indicators used to detect occurrence, development, invasion, and metastasis of breast cancer. Read More

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December 2018

imaging of structural, metabolic and functional brain changes in glaucoma.

Neural Regen Res 2019 Mar;14(3):446-449

NYU Langone Eye Center, Department of Ophthalmology, NYU School of Medicine, NYU Langone Health; Department of Radiology, NYU School of Medicine, NYU Langone Health; Center for Neural Science, Faculty of Arts and Science, New York University, New York, NY, USA.

Glaucoma, the world's leading cause of irreversible blindness, is a condition for which elevated intraocular pressure is currently the only modifiable risk factor. However, the disorder can continue to progress even at reduced intraocular pressure. This indicates additional key factors that contribute to the etiopathogenesis. Read More

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March 2019
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Beneficial effects of leptin substitution on impaired eating behavior in lipodystrophy are sustained beyond 150 weeks of treatment.

Cytokine 2019 Jan 24;113:400-404. Epub 2018 Oct 24.

Department of Medicine, University Hospital Leipzig, 04103 Leipzig, Germany. Electronic address:

Aim: Metreleptin treatment in lipodystrophy patients improves eating behavior with increased satiety and reduced hunger. However, no data are available whether effects are maintained beyond 52 weeks of treatment.

Methods: A prospective study with measurements at baseline and at >150 weeks of metreleptin treatment was performed. Read More

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January 2019

Dynamic prediction of transition to psychosis using joint modelling.

Schizophr Res 2018 Dec 7;202:333-340. Epub 2018 Jul 7.

Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Australia; Centre for Youth Mental Health, The University of Melbourne, Australia.

Considerable research has been conducted seeking risk factors and constructing prediction models for transition to psychosis in individuals at ultra-high risk (UHR). Nearly all such research has only employed baseline predictors, i.e. Read More

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December 2018

Family burden predicts functional outcome in the early course of schizophrenia beyond psychiatric symptoms and baseline functioning.

Schizophr Res 2018 Dec 7;202:328-332. Epub 2018 Jul 7.

UCLA Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Room 2240, Los Angeles, CA 90095, USA; UCLA Department of Psychology, UCLA, USA. Electronic address:

The goal of this study was to determine if family burden experienced by the families of individuals with a recent-onset of schizophrenia is associated with whether the individual is able to work or attend school during the first year of treatment. Forty-one participants with a recent first episode of schizophrenia and their families enrolled in two NIMH-funded protocols through the UCLA Aftercare Research Program completed a measure of family burden at baseline. Amount of work during this time was also recorded. Read More

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December 2018
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