2,472 results match your criteria Behavior Genetics [Journal]


Using Variation in Heritability Estimates as a Test of G × E in Behavioral Research: A Brief Research Note.

Behav Genet 2019 Feb 8. Epub 2019 Feb 8.

Criminology and Criminal Justice, Saint Louis University, Saint Louis, MO, USA.

Better characterization of the sources of phenotypic variation in human behavioural traits-stemming from genetic and environmental influences-will allow for more informed decisions about how to approach a range of challenges arising from variation, ranging from societal issues to the treatment of diseases. In particular, understanding how the environment moderates genetic influence on phenotypes (i.e. Read More

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http://dx.doi.org/10.1007/s10519-019-09948-9DOI Listing
February 2019

The Problem of Non-Shared Environment in Behavioral Genetics.

Behav Genet 2019 Feb 6. Epub 2019 Feb 6.

Department of General Psychology, Saint Petersburg State University, Universitetskaya emb. 7/9, 199034, Saint Petersburg, Russia.

The role of non-shared environment (NSE) in the development of psychological traits is usually comparable with that of the genotype. However, no specific factors of NSE with significant impact on such traits have been discovered so far. We propose that the current failures in understanding the origin of NSE are at least partly due to the fact that behavioral genetics has left out one of the key sources of phenotypic variation. Read More

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http://dx.doi.org/10.1007/s10519-019-09950-1DOI Listing
February 2019

The Gene CG6767 Affects Olfactory Behavior in Drosophila melanogaster.

Behav Genet 2019 Feb 1. Epub 2019 Feb 1.

Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, 45221-0006, USA.

Chemosensory systems mediate some of the most vital animal behaviors. However, our knowledge of the genetic mechanisms that underlie behavioral responses to olfactory cues remains fragmented. Genome-wide association mapping has greatly advanced our ability to identify candidate loci associated with variation in olfactory behavior, but functional validation of these candidates remain a necessary next step in understanding the mechanisms by which these genes influence chemoreception. Read More

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http://dx.doi.org/10.1007/s10519-019-09949-8DOI Listing
February 2019

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms.

Behav Genet 2019 Jan 18. Epub 2019 Jan 18.

Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.

We aimed to detect Attention-deficit/hyperactivity (ADHD) risk-conferring genes in adults. In children, ADHD is characterized by age-inappropriate levels of inattention and/or hyperactivity-impulsivity and may persists into adulthood. Childhood and adulthood ADHD are heritable, and are thought to represent the clinical extreme of a continuous distribution of ADHD symptoms in the general population. Read More

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http://link.springer.com/10.1007/s10519-018-09947-2
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http://dx.doi.org/10.1007/s10519-018-09947-2DOI Listing
January 2019
5 Reads

Etiological Distinction Across Dimensions of Math Anxiety.

Behav Genet 2019 Jan 18. Epub 2019 Jan 18.

Department of Psychology, The Ohio State University, Columbus, OH, 43210, USA.

Analyses have suggested math anxiety is a multidimensional construct. However, previous behavioral genetic work examining math anxiety was unidimensional. Thus, the purpose of the present study was to examine different approaches for specifying behavioral genetic models of math anxiety as a multidimensional construct. Read More

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http://link.springer.com/10.1007/s10519-018-09946-3
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http://dx.doi.org/10.1007/s10519-018-09946-3DOI Listing
January 2019
6 Reads

Did I Inherit My Moral Compass? Examining Socialization and Evocative Mechanisms for Virtuous Character Development.

Behav Genet 2019 Jan 17. Epub 2019 Jan 17.

Child Study Center, Yale University School of Medicine, New Haven, CT, USA.

Virtuous character development in children is correlated with parenting behavior, but the role of genetic influences in this association has not been examined. Using a longitudinal twin/sibling study (N = 720; Time 1 (T1) M = 12-14 years, Time 3 (T3) M = 25-27 years), the current report examines associations among parental negativity/positivity and offspring responsibility during adolescence, and subsequent young adult conscientiousness. Findings indicate that associations among parental negativity and offspring virtuous character during adolescence and young adulthood are due primarily to heritable influences. Read More

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http://link.springer.com/10.1007/s10519-018-09945-4
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http://dx.doi.org/10.1007/s10519-018-09945-4DOI Listing
January 2019
4 Reads

Physical and Cultural Inheritance Enhance Agency, but What are the Origins of this Concern to Establish a Legacy? A Nationally-Representative Twin Study of Erikson's Concept of Generativity.

Behav Genet 2019 Jan 16. Epub 2019 Jan 16.

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

Generativity-showing concern to establish and guide future generations-has been argued to be a biological adaptation central to cumulative culture and survival, but also, in turn, to be a cultural adaptation dependent on norms. From the perspective of human agency, concern for the future has played a key role in raising agency for generations that follow by creating infrastructure and cultural inheritance. Here, in a population-representative sample of 756 twin-pairs, we present the first test of the genetic and environmental structure of generativity using the Loyola Generativity Scale (short). Read More

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http://dx.doi.org/10.1007/s10519-018-9943-xDOI Listing
January 2019
5 Reads

Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies.

Behav Genet 2019 Jan 2. Epub 2019 Jan 2.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

Offspring outcomes are a function of maternal genetics operating on the intrauterine and postnatal environment, offspring genetics and environmental factors. Partitioning genetic effects into maternal and offspring components requires genotyped mother-offspring pairs or genotyped individuals with phenotypic information on themselves and their offspring. We performed asymptotic power calculations and data simulations to estimate power to detect maternal and offspring genetic effects under a range of different study designs and models. Read More

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http://dx.doi.org/10.1007/s10519-018-9944-9DOI Listing
January 2019
1 Read

Type I Error Rates and Parameter Bias in Multivariate Behavioral Genetic Models.

Behav Genet 2019 01 20;49(1):99-111. Epub 2018 Dec 20.

Department of Psychiatry and Human Genetics, Virginia Commonwealth University, Richmond, USA.

For many multivariate twin models, the numerical Type I error rates are lower than theoretically expected rates using a likelihood ratio test (LRT), which implies that the significance threshold for statistical hypothesis tests is more conservative than most twin researchers realize. This makes the numerical Type II error rates higher than theoretically expected. Furthermore, the discrepancy between the observed and expected error rates increases as more variables are included in the analysis and can have profound implications for hypothesis testing and statistical inference. Read More

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http://link.springer.com/10.1007/s10519-018-9942-y
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http://dx.doi.org/10.1007/s10519-018-9942-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345547PMC
January 2019
2 Reads

Genetically Informative Mediation Modeling Applied to Stressors and Personality-Disorder Traits in Etiology of Alcohol Use Disorder.

Behav Genet 2019 01 7;49(1):11-23. Epub 2018 Dec 7.

Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.

A statistical mediation model was developed within a twin design to investigate the etiology of alcohol use disorder (AUD). Unlike conventional statistical mediation models, this biometric mediation model can detect unobserved confounding. Using a sample of 1410 pairs of Norwegian twins, we investigated specific hypotheses that DSM-IV personality-disorder (PD) traits mediate effects of childhood stressful life events (SLEs) on AUD, and that adulthood SLEs mediate effects of PDs on AUD. Read More

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http://dx.doi.org/10.1007/s10519-018-9941-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377430PMC
January 2019
2 Reads

The Nature of the Shared Environment.

Behav Genet 2019 01 8;49(1):1-10. Epub 2018 Dec 8.

Center for Primary Health Care Research, Lund University, Malmö, Sweden.

While a standard part of twin modeling, the magnitude of shared environment (c) is rarely examined by comparing estimates obtained using other methods. To clarify these effects on familial resemblance, we estimated c for 20 diverse phenotypes in: (i) monozygotic and dizygotic twins, (ii) all step-siblings, and (iii) reared together and apart half-siblings, ascertained from the Swedish general population. The mean c estimates (± 95% CIs) differed across methods and were higher from twins (0. Read More

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http://link.springer.com/10.1007/s10519-018-9940-0
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http://dx.doi.org/10.1007/s10519-018-9940-0DOI Listing
January 2019
10 Reads

SES-of-Origin and BMI in Youth: Comparing Germany and Minnesota.

Behav Genet 2019 01 29;49(1):24-48. Epub 2018 Nov 29.

Department of Psychology, University of Minnesota, Minneapolis, USA.

Increasing obesity is a world-wide health concern. Its most commonly used indicator, body mass index (BMI), consistently shows considerable genetic and shared environmental variance throughout life, the latter particularly in youth. Several adult studies have observed less total and genetically influenced variance with higher attained SES. Read More

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http://dx.doi.org/10.1007/s10519-018-9938-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326974PMC
January 2019
2 Reads

Interpreting Behavior Genetic Models: Seven Developmental Processes to Understand.

Behav Genet 2018 Nov 22. Epub 2018 Nov 22.

Department of Psychology, University of Illinois at Urbana-Champaign, 603 East Daniel Street, Champaign, IL, 61820, USA.

Behavior genetic findings figure in debates ranging from urgent public policy matters to perennial questions about the nature of human agency. Despite a common set of methodological tools, behavior genetic studies approach scientific questions with potentially divergent goals. Some studies may be interested in identifying a complete model of how individual differences come to be (e. Read More

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http://dx.doi.org/10.1007/s10519-018-9939-6DOI Listing
November 2018
12 Reads

Symbiont-Driven Male Mating Success in the Neotropical Drosophila paulistorum Superspecies.

Behav Genet 2019 01 19;49(1):83-98. Epub 2018 Nov 19.

Department of Cell and Developmental Biology, Center of Anatomy and Cell Biology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090, Vienna, Austria.

Microbial symbionts are ubiquitous associates of living organisms but their role in mediating reproductive isolation (RI) remains controversial. We addressed this knowledge gap by employing the Drosophila paulistorum-Wolbachia model system. Semispecies in the D. Read More

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http://dx.doi.org/10.1007/s10519-018-9937-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327003PMC
January 2019
7 Reads

The Coherence Problem: Finding Meaning in GWAS Complexity.

Behav Genet 2018 Nov 16. Epub 2018 Nov 16.

Department of Psychiatry and the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298, USA.

Genome wide association studies (GWAS) for behavioral traits and psychiatric disorders have inspired both confident optimism and withering criticism. Although many recent findings from well powered GWAS have been replicated in independent data sets, the genes identified have pinned down few if any underlying causal mechanisms. Therefore, a key issue is whether or not the genes implicated by GWAS form a coherent story on their own and thus could in principle lead to insight into the biological mechanisms underlying the trait or disorder. Read More

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http://link.springer.com/10.1007/s10519-018-9935-x
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http://dx.doi.org/10.1007/s10519-018-9935-xDOI Listing
November 2018
14 Reads

A Fast Method for Estimating Statistical Power of Multivariate GWAS in Real Case Scenarios: Examples from the Field of Imaging Genetics.

Behav Genet 2019 01 15;49(1):112-121. Epub 2018 Nov 15.

Queensland Brain Institute, The University of Queensland, Brisbane, 4072, Australia.

In GWAS of imaging phenotypes (e.g., by the ENIGMA and CHARGE consortia), the growing number of phenotypes considered presents a statistical challenge that other fields are not experiencing (e. Read More

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http://link.springer.com/10.1007/s10519-018-9936-9
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http://dx.doi.org/10.1007/s10519-018-9936-9DOI Listing
January 2019
10 Reads

The Role of Emergence in Genetically Informed Relationships Research: A Methodological Analysis.

Behav Genet 2018 Oct 24. Epub 2018 Oct 24.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

This paper provides a critical analysis of genetically informed research on relationships, with an emphasis on relationships among unrelated individuals (e.g., spouses). Read More

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http://link.springer.com/10.1007/s10519-018-9934-y
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http://dx.doi.org/10.1007/s10519-018-9934-yDOI Listing
October 2018
11 Reads

Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster.

Behav Genet 2019 01 19;49(1):60-82. Epub 2018 Oct 19.

Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.

Circadian rhythms influence physiological processes from sleep-wake cycles to body temperature and are controlled by highly conserved cycling molecules. Although the mechanistic basis of the circadian clock has been known for decades, the extent to which circadian rhythms vary in nature and the underlying genetic basis for that variation is not well understood. We measured circadian period (Ʈ) and rhythmicity index in the Drosophila Genetic Reference Panel (DGRP) and observed extensive genetic variation in both. Read More

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http://link.springer.com/10.1007/s10519-018-9932-0
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http://dx.doi.org/10.1007/s10519-018-9932-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326971PMC
January 2019
13 Reads

I Smell a Mouse: Indirect Genetic Effects on Voluntary Wheel-Running Distance, Duration and Speed.

Behav Genet 2019 01 15;49(1):49-59. Epub 2018 Oct 15.

Department of Biology, University of Ottawa, Ottawa, ON, Canada.

Indirect genetic effects (IGEs; the heritable influence of one organism on a conspecific) can affect the evolutionary dynamics of complex traits, including behavior. Voluntary wheel running is an important model system in quantitative genetic studies of behavior, but the possibility of IGEs on wheel running and its components (time spent running and average running speed) has not been examined. Here, we analyze a dataset from a replicated selection experiment on wheel running (11,420 control and 26,575 selected mice measured over 78 generations) in which the standard measurement protocol allowed for the possibility of IGEs occurring through odors because mice were provided with clean cages attached to a clean wheel or a wheel previously occupied by another mouse for 6 days. Read More

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http://link.springer.com/10.1007/s10519-018-9930-2
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http://dx.doi.org/10.1007/s10519-018-9930-2DOI Listing
January 2019
10 Reads

Free Will, Determinism, and Intuitive Judgments About the Heritability of Behavior.

Behav Genet 2018 Oct 12. Epub 2018 Oct 12.

Department of Psychology, University of Minnesota Twin Cities, 75 East River Rd., Minneapolis, MN, 55455, USA.

The fact that genes and environment contribute differentially to variation in human behaviors, traits and attitudes is central to the field of behavior genetics. Perceptions about these differential contributions may affect ideas about human agency. We surveyed two independent samples (N = 301 and N = 740) to assess beliefs about free will, determinism, political orientation, and the relative contribution of genes and environment to 21 human traits. Read More

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http://link.springer.com/10.1007/s10519-018-9931-1
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http://dx.doi.org/10.1007/s10519-018-9931-1DOI Listing
October 2018
3 Reads

Behavior Genetics Association 48th Annual Meeting Abstracts.

Authors:

Behav Genet 2018 Oct 4:454-526. Epub 2018 Oct 4.

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http://dx.doi.org/10.1007/s10519-018-9929-8DOI Listing
October 2018
1 Read

Parent- and Observer-Rated Positive Affect in Early Childhood: Genetic Overlap and Environmental Specificity.

Behav Genet 2018 11 26;48(6):432-439. Epub 2018 Sep 26.

Department of Psychological & Brain Sciences, Boston University, 64 Cummington Mall, Room 100, Boston, MA, 02215, USA.

The sources of individual differences in both observed and parent-rated positive affect (PA) were examined in a sample of 304 3-year-old twin pairs (140 MZ, 164 DZ). Based on model-fitting analyses, individual differences in observed PA were attributed to moderate genetic and high nonshared environmental factors, but not shared environmental factors. In contrast, shared environmental effects accounted for over half of the variance in parent-rated PA and genetic and nonshared environmental effects were more modest. Read More

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http://dx.doi.org/10.1007/s10519-018-9924-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186175PMC
November 2018
9 Reads

Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization.

Behav Genet 2018 11 21;48(6):421-431. Epub 2018 Sep 21.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, P.O. Box 980126, Richmond, VA, 23298-0126, USA.

The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Read More

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http://dx.doi.org/10.1007/s10519-018-9923-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233884PMC
November 2018
4 Reads

Effects of Repeated Treatment with Midazolam in SHR and SLA16 Rat Strains in the Triple Test.

Behav Genet 2018 11 19;48(6):440-450. Epub 2018 Sep 19.

Laboratório de Genética do Comportamento, Departamento de Biologia Celular, Embriologia e Genética, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, BEG, bloco C, 3° andar, sala 310C, Florianópolis, SC, CEP 88.040-900, Brazil.

We exposed male and female rats of SHR (Spontaneously Hypertensive Rats) and SLA16 (SHR.LEW-Anxrr16) strains, in a non-drugged state, for five consecutive days to the Triple Test (experiment 1); or after repeated treatment with midazolam (MDZ), for four consecutive days. The fifth day was performed without treatment (experiment 2). Read More

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http://dx.doi.org/10.1007/s10519-018-9922-2DOI Listing
November 2018
1 Read

Correction to: Behavioral Genetics and Attributions of Moral Responsibility.

Behav Genet 2018 Sep 8. Epub 2018 Sep 8.

Center for Research on Ethical, Legal and Social Implications of Psychiatric, Neurologic and Behavioral Genetics, Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.

The original version of this article unfortunately contained a few mistakes in the Introduction section. Read More

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http://dx.doi.org/10.1007/s10519-018-9921-3DOI Listing
September 2018
1 Read

Understanding "What Could Be": A Call for 'Experimental Behavioral Genetics'.

Behav Genet 2018 Aug 13. Epub 2018 Aug 13.

Department of Psychology, Michigan State University, 107D Psychology Building, East Lansing, MI, 48824, USA.

Behavioral genetic (BG) research has yielded many important discoveries about the origins of human behavior, but offers little insight into how we might improve outcomes. We posit that this gap in our knowledge base stems in part from the epidemiologic nature of BG research questions. Namely, BG studies focus on understanding etiology as it currently exists, rather than etiology in environments that could exist but do not as of yet (e. Read More

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http://dx.doi.org/10.1007/s10519-018-9918-yDOI Listing
August 2018
2 Reads

Nurturing Our Better Nature: A Proposal for Cognitive Integrity as a Foundation for Autonomous Living.

Behav Genet 2018 Aug 12. Epub 2018 Aug 12.

Department of Philosophy, University of Birmingham, Birmingham, UK.

As we account for the genetic and environmental influences on morally-relevant character traits like intellectual honesty, industriousness, and self-control, do we risk becoming ever less accountable to ourselves? Behavioral genetic research suggests that about half the variance in such character traits is likely attributable to heredity, and a small fraction to the shared family environment. The remaining 40-60% is explained by neither genes nor family upbringing. This raises the question: how active a role can individuals play in shaping their own character? What, if anything, can and should one do to take responsibility for the kind of person one becomes? This paper sketches a novel theoretical proposal for addressing these questions, by drawing on several previously disparate lines of research within behavior genetics, philosophy, and experimental psychology. Read More

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http://dx.doi.org/10.1007/s10519-018-9919-xDOI Listing
August 2018
13 Reads

Behavioral Genetics and Attributions of Moral Responsibility.

Behav Genet 2018 Aug 9. Epub 2018 Aug 9.

Center for Research on Ethical, Legal and Social Implications of Psychiatric, Neurologic and Behavioral Genetics, Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.

While considerable research has examined how genetic explanations for behavior impact assessments of moral responsibility, results across studies have been inconsistent. Some studies suggest that genetic accounts diminish ascriptions of responsibility, but others show no effect. Nonetheless, conclusions from behavior genetics are increasingly mobilized on behalf of defendants in court, suggesting a widespread intuition that this sort of information is relevant to assessments of blameworthiness. Read More

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http://dx.doi.org/10.1007/s10519-018-9916-0DOI Listing
August 2018
2 Reads

Characterizing the Relation Between Expression QTLs and Complex Traits: Exploring the Role of Tissue Specificity.

Behav Genet 2018 09 20;48(5):374-385. Epub 2018 Jul 20.

Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Measurement of gene expression levels and detection of eQTLs (expression quantitative trait loci) are difficult in tissues with limited sample availability, such as the brain. However, eQTL overlap between tissues might be high, which would allow for inference of eQTL functioning in the brain via eQTLs detected in readily accessible tissues, e.g. Read More

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http://dx.doi.org/10.1007/s10519-018-9914-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097736PMC
September 2018
5 Reads

Resting Heart Rate Variability (HRV) in Adolescents and Young Adults from a Genetically-Informed Perspective.

Behav Genet 2018 Jul 11. Epub 2018 Jul 11.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 800 E. Leigh St, Biotech One, Suite 101, Richmond, VA, 23219, USA.

Reduced heart rate variability (HRV) is associated with cardiac morbidity, mortality, and negative psychopathology. Most research concerning genetic influences on HRV has focused on adult populations, with fewer studies investigating the developmental period of adolescence and emerging adulthood. The current study estimated the genetic and environmental contributions to resting HRV in a sample of twins using various HRV time domain metrics to assess autonomic function across two different time measurement intervals (2. Read More

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http://dx.doi.org/10.1007/s10519-018-9915-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345603PMC
July 2018
6 Reads

Revisiting the Children-of-Twins Design: Improving Existing Models for the Exploration of Intergenerational Associations.

Behav Genet 2018 09 30;48(5):397-412. Epub 2018 Jun 30.

Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College, De Crespigny Park, Box PO80, SE5 8AF, London, UK.

Datasets comprising twins and their children can be a useful tool for understanding the nature of intergenerational associations between parent and offspring phenotypes. In the present article we explore structural equation models previously used to analyse Children-of-Twins data, highlighting some limitations and considerations. We then present new variants of these models, showing that extending the models to include multiple offspring per parent addresses several of the limitations discussed. Read More

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http://dx.doi.org/10.1007/s10519-018-9912-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097723PMC
September 2018
7 Reads

The Influence of Dyslexia Candidate Genes on Reading Skill in Old Age.

Behav Genet 2018 09 29;48(5):351-360. Epub 2018 Jun 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, UK.

A number of candidate genes for reading and language impairment have been replicated, primarily in samples of children with developmental disability or delay, although these genes are also supported in adolescent population samples. The present study used a systematic approach to test 14 of these candidate genes for association with reading assessed in late adulthood (two cohorts with mean ages of 70 and 79 years). Gene-sets (14 candidates, axon-guidance and neuron migration pathways) and individual SNPs within each gene of interest were tested for association using imputed data referenced to the 1000 genomes European panel. Read More

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http://dx.doi.org/10.1007/s10519-018-9913-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097729PMC
September 2018
8 Reads

Sex Differences in the Genetic and Environmental Influences on Self-Reported Non-aggressive and Aggressive Conduct Disorder Symptoms in Early and Middle Adolescence.

Behav Genet 2018 07 11;48(4):271-282. Epub 2018 Jun 11.

Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.

Decades of research into the etiology of conduct disorder (CD) has yet to yield a consensus on the existence of sex differences in underlying genetic and environmental influences. This may be partly due to the failure of many previous studies to make a distinction between non-aggressive and aggressive CD symptoms or test for potential developmental changes in sex differences in the etiology of conduct problems. To address these gaps, we fit a series of univariate and bivariate biometric sex-difference models to self-reported non-aggressive and aggressive CD symptoms in a community-based sample of twins (N = 1548, ages 9-17 year), grouped into ages 9-13 and 14-17 years. Read More

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http://dx.doi.org/10.1007/s10519-018-9907-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051422PMC
July 2018
3 Reads

Indirect Genetic Effects for Growth in Pigs Affect Behaviour and Weight Around Weaning.

Behav Genet 2018 Jun 19. Epub 2018 Jun 19.

Adaptation Physiology Group, Wageningen University and Research, Wageningen, The Netherlands.

Selection for indirect genetic effects (IGE), i.e. the genetic effect of an individual on a trait of another individual, is a promising avenue to increase trait values in plant and animal breeding. Read More

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http://dx.doi.org/10.1007/s10519-018-9911-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097724PMC
June 2018
3 Reads

Causal Reasoning About Human Behavior Genetics: Synthesis and Future Directions.

Behav Genet 2018 Jun 19. Epub 2018 Jun 19.

Department of Philosophy and Charles Perkins Centre, University of Sydney, Sydney, NSW, 2006, Australia.

When explaining the causes of human behavior, genes are often given a special status. They are thought to relate to an intrinsic human 'essence', and essentialist biases have been shown to skew the way in which causation is assessed. Causal reasoning in general is subject to other pre-existing biases, including beliefs about normativity and morality. Read More

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http://dx.doi.org/10.1007/s10519-018-9909-zDOI Listing
June 2018
3 Reads

Genetic and Environmental Influences on Verbal Fluency in Middle Age: A Longitudinal Twin Study.

Behav Genet 2018 Jun 19. Epub 2018 Jun 19.

Department of Psychiatry, Center for Behavior Genetics of Aging, University of California, San Diego, 9500 Gilman Dr. (MC 0738), La Jolla, CA, 92093, USA.

Mounting evidence suggests that measures of phonemic fluency and semantic fluency are differentially associated with other cognitive and health phenotypes, but few studies have examined their shared and unique variance, especially using genetically-informative designs. In this study, 1464 middle-aged twins completed six fluency subtests at up to two time-points (mean age 56 and 62 years). Confirmatory factor analyses supported a two-factor solution: a General Fluency latent factor explained variation in all six subtests and a Semantic-Specific factor accounted for additional variance in semantic subtests. Read More

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http://dx.doi.org/10.1007/s10519-018-9910-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301139PMC
June 2018
3 Reads

Neurocognitive Functioning in Patients with 22q11.2 Deletion Syndrome: A Meta-Analytic Review.

Behav Genet 2018 Jun 19. Epub 2018 Jun 19.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

The 22q11.2 deletion syndrome (22q11.2DS) is a known risk factor for development of schizophrenia and is characterized by a complex neuropsychological profile. Read More

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http://dx.doi.org/10.1007/s10519-018-9903-5DOI Listing
June 2018
4 Reads

Genes and Virtue: Exploring How Heritability Beliefs Shape Conceptions of Virtue and Its Development.

Behav Genet 2018 Jun 19. Epub 2018 Jun 19.

Department of Psychology, The Pennsylvania State University, 431 Moore Building, University Park, PA, 16802, USA.

In this paper, we provide an overview of our ongoing project in the Genetics and Human Agency Initiative sponsored by the John Templeton Foundation. Our project focuses on the ways that lay beliefs about the heritability of virtue influence reasoning about the nature of virtue, parenting behaviors, and the development of virtue in children. First, we provide philosophical perspectives on the nature of virtue and suggest that viewing virtue as a malleable skill may have important advantages. Read More

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http://dx.doi.org/10.1007/s10519-018-9908-0DOI Listing
June 2018
3 Reads

High Incidence of Copy Number Variants in Adults with Intellectual Disability and Co-morbid Psychiatric Disorders.

Behav Genet 2018 Jun 7. Epub 2018 Jun 7.

Genetics lab, UDIAT-centre diagnostic. Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí I3PT. Universitat Autònoma de Barcelona, C/Parc Tauli,1, 08208, Sabadell, Barcelona, Spain.

A genetic analysis of unexplained mild-moderate intellectual disability and co-morbid psychiatric or behavioural disorders is not systematically conducted in adults. A cohort of 100 adult patients affected by both phenotypes were analysed in order to identify the presence of copy number variants (CNVs) responsible for their condition identifying a yield of 12.8% of pathogenic CNVs (19% when including clinically recognizable microdeletion syndromes). Read More

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http://dx.doi.org/10.1007/s10519-018-9902-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028865PMC
June 2018
25 Reads

Extending Causality Tests with Genetic Instruments: An Integration of Mendelian Randomization with the Classical Twin Design.

Behav Genet 2018 Jun 7. Epub 2018 Jun 7.

Department of Biological Psychology, Vrije Universiteit Amsterdam, Transitorium 2B03, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.

Although experimental studies are regarded as the method of choice for determining causal influences, these are not always practical or ethical to answer vital questions in health and social research (e.g., one cannot assign individuals to a "childhood trauma condition" in studying the causal effects of childhood trauma on depression). Read More

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http://dx.doi.org/10.1007/s10519-018-9904-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028857PMC
June 2018
17 Reads

Correlates of Positive Parenting Behaviors.

Behav Genet 2018 Jun 6. Epub 2018 Jun 6.

Department of Psychology and Neuroscience, University of Colorado Boulder, 345 UCB Muenzinger D244, Boulder, CO, 80309-0345, USA.

The present study examined the influence of maternal and child characteristics on parenting behaviors in a genetically informative study. The participants were 976 twins and their mothers from the Colorado Longitudinal Twin Study and the Twin Infant Project. Indicators of positive parenting were coded during parent-child interactions when twins were 7-36 months old. Read More

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http://dx.doi.org/10.1007/s10519-018-9906-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281807PMC
June 2018
26 Reads
3.210 Impact Factor

The Relationship Between Personality and Somatic and Psychological Distress: A Comparison of Chinese and Australian Adolescents.

Behav Genet 2018 Jun 5. Epub 2018 Jun 5.

Tianjin University, Tianjin, People's Republic of China.

The extent to which correlations between personality domains and physical and psychological health generalize cross-culturally is unclear. We compared the strength of associations between the personality domains and somatic and psychological distress in Chinese (N = 2069) and a genetically informative sample of Australian (N = 2936) adolescents. We also examined the genetic and environmental etiology between personality, somatic and psychological distress in an Australian sample of 390 monozygotic twins and 698 dizygotic twins. Read More

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http://link.springer.com/10.1007/s10519-018-9905-3
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http://dx.doi.org/10.1007/s10519-018-9905-3DOI Listing
June 2018
5 Reads

Sociability in Fruit Flies: Genetic Variation, Heritability and Plasticity.

Behav Genet 2018 05 23;48(3):247-258. Epub 2018 Apr 23.

Animal Behaviour Group, Department of Psychology, Neuroscience & Behaviour, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada.

Sociability, defined as individuals' propensity to participate in non-aggressive activities with conspecifics, is a fundamental feature of behavior in many animals including humans. However, we still have a limited knowledge of the mechanisms and evolutionary biology of sociability. To enhance our understanding, we developed a new protocol to quantify sociability in fruit flies (Drosophila melanogaster). Read More

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http://link.springer.com/10.1007/s10519-018-9901-7
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http://dx.doi.org/10.1007/s10519-018-9901-7DOI Listing
May 2018
6 Reads

Etiology of Stability and Growth of Internalizing and Externalizing Behavior Problems Across Childhood and Adolescence.

Behav Genet 2018 07 20;48(4):298-314. Epub 2018 Apr 20.

Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.

Internalizing and externalizing behaviors are heritable, and show genetic stability during childhood and adolescence. Less work has explored how genes influence individual differences in developmental trajectories. We estimated ACE biometrical latent growth curve models for the Teacher Report Form (TRF) and parent Child Behavior Checklist (CBCL) internalizing and externalizing scales from ages 7 to 16 years in 408 twin pairs from the Colorado Longitudinal Twin Study. Read More

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http://dx.doi.org/10.1007/s10519-018-9900-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026557PMC
July 2018
4 Reads

Social Support and Strain Across Close Relationships: A Twin Study.

Behav Genet 2018 05 12;48(3):173-186. Epub 2018 Apr 12.

Division of Health Data and Digitalization, Center for Fertility and Health and Department of Genetics and Bioinformatics, The Norwegian Institute of Public Health, PO Box 4404, 0403, Oslo, Norway.

Social relationships play a critical role in health and well-being throughout life. We analyzed the genetic and environmental variance co-variance structure for social support and strain across four sets of relationships including with one's co-twin, spouse/partner, family and friends. The sample included 5288 Norwegian twins aged 40-80. Read More

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http://dx.doi.org/10.1007/s10519-018-9899-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934464PMC
May 2018
4 Reads

Facilitatory Effect of IL-6 Deficiency on Long-Term Spatial Memory in Young Adult Mice.

Behav Genet 2018 05 4;48(3):236-246. Epub 2018 Apr 4.

Department of General and Experimental Pathology, Medical University of Bialystok, Mickiewicza 2c, 15-222, Bialystok, Poland.

The significance of interleukin 6 (IL-6) in long-term reference memory was tested in the Morris water maze (MWM) in 4-month-old C57BL/6J IL-6-deficient (IL-6 KO) and control mice. Three-day learning measured by escape latency time to find the hidden platform was comparable in both genotypes. In a single probe trial performed 7 days later, without the platform, latency to the platform site and path length to the target place were significantly shorter (p < 0. Read More

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http://dx.doi.org/10.1007/s10519-018-9896-0DOI Listing
May 2018
4 Reads

Genetic and Environmental Influences on Language Ability in Older Adults: Findings from the Older Australian Twins Study.

Behav Genet 2018 05 4;48(3):187-197. Epub 2018 Apr 4.

Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.

We used a sub-sample from the Older Australian Twins Study to estimate the heritability of performance on three tests of language ability: Boston Naming Test (BNT), Letter/Phonemic Fluency (FAS) and Category/Semantic Fluency (CFT) Tests. After adjusting for age, sex, education, mood, and global cognition (GC), heritability estimates obtained for the three tests were 0.35, 0. Read More

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http://dx.doi.org/10.1007/s10519-018-9897-zDOI Listing
May 2018
4 Reads