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    Ultrastructural analysis of early toxic effects produced by bee venom phospholipase A2 and melittin in Sertoli cells in rats.
    Toxicon 2018 Jan 8;141:94-103. Epub 2017 Dec 8.
    Department of Cell and Molecular Biology, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. Electronic address:
    In this study, we aimed to investigate the testicular toxicity of two molecules derived from bee venom (BV): phospholipase A2 (PlA2) and melittin (Mlt). Ultrastructural effects of purified BV PlA2 and Mlt were assessed consecutive to repeated dose (30 days) and acute toxicity studies. For the subchronic treatment, PlA2 and Mlt were injected in daily doses equivalent to those released by a bee sting (105 μg PlA2/kg/day and 350 μg Mlt/kg/day), while in the acute treatment their doses corresponded to those released by 100 bee stings (9. Read More

    Immunological differences between insect venom-allergic patients with and without immunotherapy and asymptomatically sensitized subjects.
    Allergy 2017 Nov 23. Epub 2017 Nov 23.
    Department of Dermatology and Venerology, Medical University of Graz, Graz, Austria.
    Background: Currently available tests are unable to distinguish between asymptomatic sensitization and clinically relevant Hymenoptera venom allergy. A reliable serological marker to monitor venom immunotherapy (VIT) does also not exist. Our aim was to find reliable serological markers to predict tolerance to bee and vespid stings. Read More

    Relapse of nephrotic syndrome triggered by Kawasaki disease.
    CEN Case Rep 2017 Nov 15. Epub 2017 Nov 15.
    Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, Fukushima, 960-1295, Japan.
    Minor infections, allergies, insect bites, and bee stings are commonly reported causes of nephrotic syndrome (NS). Herein, we report, to the best of our knowledge, the first case of NS relapse due to Kawasaki disease (KD). An 8-year-old boy presented with high fever of 4-day duration. Read More

    The sting of a honey bee: An unusual subconjunctival foreign body.
    Indian J Ophthalmol 2017 Nov;65(11):1226-1228
    Tej Kohli Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India.
    Ocular foreign bodies (FBs) are often encountered in clinical practices. However, there are cases in which the presence of the FB is difficult to diagnose based on mere history taking and/or clinical examination. We herein present a case of unusual subconjunctival foreign body in the form of the sting of a honey bee in a 63-year-old farmer. Read More

    Bee or Wasp Sting.
    Wounds 2017 Sep;29(9):E70-E72
    University of Calgary, Calgary, Alberta, Canada; and Alberta Children's Hospital, Calgary, Alberta, Canada.
    While jogging in a local park in Hong Kong, a 55-year-old, previously healthy man was stung on the ventral aspect of his right wrist. The tiny stinger was gently removed with nail cutters and examined under a microscope at 80x magni cation; plucking the stinger is ill- advised as this may inject more venom into the wounded site. Two days after stinging, the microscopic appearance of the stinger con rmed the diagnosis to be from a bee instead of a wasp or other insect. Read More

    Larval honey bees infected with Nosema ceranae have increased vitellogenin titers as young adults.
    Sci Rep 2017 Oct 26;7(1):14144. Epub 2017 Oct 26.
    Section of Ecology, Behavior, and Evolution, Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, MC0116, La Jolla, CA 92093, USA.
    Nosema ceranae is a pervasive and widespread honey bee pathogen that is associated with colony declines and has recently been shown to infect larval honey bees. In adult bees, Nosema infection is known to alter levels of a key protein, vitellogenin (Vg), which is necessary for egg-laying in queens, brood food production in workers, and proper immune function in all female bees. We therefore tested the effects of larval worker infection on hemolymph Vg titers. Read More

    A honey bee can threat ear: Sudden sensorineural hearing loss.
    Am J Emerg Med 2017 Nov 2;35(11):1788.e1-1788.e3. Epub 2017 Aug 2.
    Yüzüncü Yıl University, Faculty of Medicine, Department of Otorhinolaryngology, Van, Turkey.
    Sudden sensorineural hearing loss is an otologic emergency. Many etiological factors can lead to this pathology. Honey bee (Apis mellifera) sting may lead to local and systemic reactions due to sensitization of the patient. Read More

    Individual perception of bees: Between perceived danger and willingness to protect.
    PLoS One 2017 29;12(6):e0180168. Epub 2017 Jun 29.
    Department of Biology Education, University of Bayreuth, Bayreuth, Germany.
    The current loss of biodiversity has found its way into the media. Especially the loss of bees as pollinators has recently received much attention aiming to increase public awareness about the consequence of pollinator loss and strategies for protection. However, pollinating insects like bees often prompt considerable anxiety. Read More

    Acute kidney injury complicating bee stings - a review.
    Rev Inst Med Trop Sao Paulo 2017 Jun 1;59:e25. Epub 2017 Jun 1.
    Universidade Federal do Ceará, Faculdade de Medicina, Departamento de Medicina Clínica, Fortaleza, Ceará, Brazil.
    Bee stings can cause severe reactions and have caused many victims in the last years. Allergic reactions can be triggered by a single sting and the greater the number of stings, the worse the prognosis. The poisoning effects can be systemic and can eventually cause death. Read More

    Safety and efficacy of venom immunotherapy: a real life study.
    Postepy Dermatol Alergol 2017 Apr 13;34(2):159-167. Epub 2017 Apr 13.
    Clinical Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland.
    Introduction: Venom immunotherapy (VIT) is recommended as the first-line treatment for patients allergic to Hymenoptera venom.

    Aim: To analyze the safety and efficacy of VIT in a real life setting.

    Material And Methods: One hundred and eighty patients undergoing VIT were studied to evaluate the safety, efficacy, incidence and nature of symptoms after field stings and adverse reactions to VIT. Read More

    Component Resolved Diagnosis in Hymenoptera Anaphylaxis.
    Curr Allergy Asthma Rep 2017 Jun;17(6):38
    Department of Dermatology and Allergy Biederstein, Technische Universität München, Biedersteiner Straße 29, 80802, Munich, Germany.
    Purpose Of Review: Hymenoptera anaphylaxis is one of the leading causes of severe allergic reactions and can be fatal. Venom-specific immunotherapy (VIT) can prevent a life-threatening reaction; however, confirmation of an allergy to a Hymenoptera venom is a prerequisite before starting such a treatment. Component resolved diagnostics (CRD) have helped to better identify the responsible allergen. Read More

    Long-Term Follow-Up of Children after Venom Immunotherapy: Low Adherence to Anaphylaxis Guidelines.
    Int Arch Allergy Immunol 2017 6;172(3):167-172. Epub 2017 Apr 6.
    Division of Pediatric Pneumology and Allergy, University Hospital for Children and Adolescents, Leipzig, Germany.
    Background: Data on the long-term outcome of children after specific venom immunotherapy (VIT) are limited. Therefore, we assessed sting recurrence and anaphylaxis relapse rates as well as adherence to anaphylaxis guidelines with regard to the availability of emergency equipment and education status.

    Methods: For this long-term survey, data of 311 children with a history of anaphylactic reactions to hymenoptera stings were collected by chart review. Read More

    A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom.
    J Venom Anim Toxins Incl Trop Dis 2017 16;23:14. Epub 2017 Mar 16.
    Department of Tropical Diseases, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, SP Brazil.
    Background: Envenomation caused by multiple stings from Africanized honeybees Apis mellifera constitutes a public health problem in the Americas. In 2015, the Brazilian Ministry of Health reported 13,597 accidents (incidence of seven cases per 100,000 inhabitants) with 39 deaths (lethality of 0.25%). Read More

    Pharmacist use of the electronic medical record to identify adults at risk for anaphylaxis without epinephrine for self-administration.
    J Am Pharm Assoc (2003) 2017 May - Jun;57(3):369-374.e2. Epub 2017 Mar 8.
    Objectives: To describe an innovative pharmacist-led approach, with the use of electronic medical record (EMR) data, to identify patients at risk of anaphylaxis in need of epinephrine auto-injector (EAI) for self-administration.

    Setting: An urban free health care center for an uninsured indigent adult population in Pittsburgh, PA.

    Practice Innovation: In this pilot service, patients with allergy history fields containing the words "anaphylaxis," "nut," "bee," or "shellfish" were screened for inclusion. Read More

    Kidney injury in a dog following bee sting-associated anaphylaxis.
    Can Vet J 2017 Mar;58(3):265-269
    University of Florida College of Veterinary Medicine - Small Animal Clinical Sciences, Gainesville, Florida, USA (Buckley, Corrie, Schaer); Canada West Veterinary Specialists - Emergency & Critical Care, Vancouver, British Columbia (Bandt).
    This report describes a case of honeybee envenomation in a dog that developed anaphylaxis after being stung by approximately 10 bees. The dog subsequently developed acute kidney injury. The dog had a previous mild increase in blood urea nitrogen with normal creatinine, possibly indicating an insidious chronic renal degenerative process that went into acute decompensation at the time of bee envenomation. Read More

    Late Onset of Acute Urticaria after Bee Stings.
    Case Rep Dermatol 2016 Sep-Dec;8(3):341-343. Epub 2016 Dec 1.
    Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.
    Here we report the cases of five patients with a late onset of acute urticaria after a bee sting. The ages of the five Japanese patients ranged from 33 to 86 years (median: 61). All patients had no history of an allergic reaction to bee stings. Read More

    Pre-hospital treatment of bee and wasp induced anaphylactic reactions: a retrospective study.
    Scand J Trauma Resusc Emerg Med 2017 Jan 14;25(1). Epub 2017 Jan 14.
    Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Sdr. Boulevard 29, Odense, DK-5000, Denmark.
    Background: Bee and wasp stings are among the most common triggers of anaphylaxis in adults representing around 20% of fatal anaphylaxis from any cause. Data of pre-hospital treatment of bee and wasp induced anaphylactic reactions are sparse. This study aimed to estimate the incidence of bee and wasp induced anaphylactic reactions, the severity of the reactions and to correlate the pre-hospital treatment with the severity of the anaphylactic reaction. Read More

    IgE-Api m 4 Is Useful for Identifying a Particular Phenotype of Bee Venom Allergy.
    J Investig Allergol Clin Immunol 2016;26(6):355-361
    Maimonides Biomedical Research Institute of Cordoba (IMIBIC).
    Background And Objective: Different clinical behaviors have been identified in patients allergic to bee venom. Compound-resolved diagnosis could be an appropriate tool for investigating these differences. The aims of this study were to analyze whether specific IgE to Api m 4 (sIgE-Api m 4) can identify a particular kind of bee venom allergy and to describe response to bee venom immunotherapy (bVIT). Read More

    Morphology of rare exogenous materials in dermatopathology.
    J Cutan Pathol 2017 Mar 12;44(3):237-248. Epub 2017 Jan 12.
    Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
    Dermatopathologists are occasionally challenged by exogenous materials found in their biopsies. Recognition of most of the structures and morphological parts of foreign materials is not always easy because most of the literature thus far has focused on the study of the histological and histopathological aspects of human tissues, as well as on the granulomatous response elicited by such foreign bodies. However, there are some cases of rare exogenous material in biopsies, mainly published as case reports; and dermatopathologists often lose precious time searching for information about such cases. Read More

    Simplification of intradermal skin testing in Hymenoptera venom allergic children.
    Ann Allergy Asthma Immunol 2017 03 13;118(3):326-332. Epub 2016 Dec 13.
    Department of Pediatrics, Icahn School of Medicine at Mount Sinai, Jaffe Food Allergy Institute, New York, New York.
    Background: The direct comparison between children and adults with Hymenoptera venom anaphylaxis (HVA) has never been extensively reported. Severe HVA with IgE-documented mechanism is the recommendation for venom immunotherapy, regardless of age.

    Objective: To determine the differences in the basic diagnostic profile between children and adults with severe HVA and its practical implications. Read More

    Poison and alarm: the Asian hornet Vespa velutina uses sting venom volatiles as an alarm pheromone.
    J Exp Biol 2017 02 6;220(Pt 4):645-651. Epub 2016 Dec 6.
    Division of Biological Sciences, Section of Ecology, Behavior and Evolution, University of California, San Diego, La Jolla, CA 92093, USA.
    In colonial organisms, alarm pheromones can provide a key fitness advantage by enhancing colony defence and warning of danger. Learning which species use alarm pheromone and the key compounds involved therefore enhances our understanding of how this important signal has evolved. However, our knowledge of alarm pheromones is more limited in the social wasps and hornets compared with the social bees and ants. Read More

    Acute ischemic stroke and severe multiorgan dysfunction due to multiple bee stings.
    Turk J Emerg Med 2016 Sep 29;16(3):126-128. Epub 2016 Sep 29.
    Department of Internal Medicine, Samsun Training and Research Hospital, Samsun, Turkey.
    Various manifestations after bee sting have been described. Local reactions, such as pain, wheal, flare, edema and swelling, are common and generally self-limiting. Uncommonly manifestations like vomiting, diarrhea, dyspnea, generalized edema, acute renal failure, anaphylactic shock, myocardial infarction, hypotension, collapse, pulmonary hemorrhage, acute hemorrhagic pancreatitis, and atrial fibrillation may occur. Read More

    Safety of essential bee venom pharmacopuncture as assessed in a randomized controlled double-blind trial.
    J Ethnopharmacol 2016 Dec 10;194:774-780. Epub 2016 Nov 10.
    Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, 858 Eonju-ro, Gangnam-gu, Seoul, Republic of Korea. Electronic address:
    Ethnopharmacological Relevance: While bee venom (BV) pharmacopuncture use is common in Asia, frequent occurrence of allergic reactions during the treatment process is burdensome for both practitioner and patient.

    Aim Of The Study: This study compared efficacy and safety in isolated and purified essential BV (eBV) pharmacopuncture filtered for phospholipase A2 (PLA2) and histamine sections, and original BV to the aim of promoting safe BV pharmacopuncture use.

    Materials And Methods: In in vitro, we examined the effect of BV and eBV on nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW 264. Read More

    Possible complication of bee stings and a review of the cardiac effects of bee stings.
    BMJ Case Rep 2016 Nov 1;2016. Epub 2016 Nov 1.
    Department of Cardiology, Medical College Hospital, Trivandrum, Trivandrum, Kerala, India.
    We report the case of a patient who, ∼3 weeks after multiple bee stings, developed a prolonged heart block, syncope and cardiac arrest. This required a temporary pacemaker to be implanted, which was later replaced with a permanent pacemaker. An ECG taken following surgery for a fractured humerus 6 years earlier was reportedly normal. Read More

    Dose-dependence of protection from systemic reactions to venom immunotherapy by omalizumab.
    Clin Mol Allergy 2016 24;14:14. Epub 2016 Oct 24.
    Allergy Unit, Sant'Anna Hospital, ASST Lariana, Via Napoleona 60, 22100 Como, Italy.
    Background: Systemic reactions (SR) to venom immunotherapy (VIT) are rare but may occur, with a rate significantly higher for honeybee than for vespid VIT. In patients with repeated SRs to VIT it is difficult to reach the maintenance dose of venom and pre-treatment with omalizumab is indicated, as shown by some studies reporting its preventative capacity, when antihistamines and corticosteroids are ineffective.

    Case Presentation: We present the case of a 47 years old woman allergic to bee venom who experienced two severe SRs after bee stings and several SRs to VIT with bee venom. Read More

    [Insect venom allergies : Update 2016 for otorhinolaryngologists].
    HNO 2016 Dec;64(12):927-942
    Zentrum für Rhinologie und Allergologie, An den Quellen 10, 65183, Wiesbaden, Deutschland.
    Due to the increasing incidence of hymenoptera venom allergies and the potentially life-threatening reactions, it is important for otolaryngologists working in allergology to have an understanding of modern diagnostic and treatment standards for this allergic disease. Molecular diagnosis with recombinant single allergens from bee and wasp venom components improves the diagnostics of insect venom allergies, particularly in patients with double-positive extract-based test results. Detection of specific sensitizations to bee or wasp venom enables double sensitizations to be better distinguished from cross-reactivity. Read More

    [Mortal poisoning by bee stings in a child: Study of a case observed in the regional hospital of Maradi (Niger)].
    Bull Soc Pathol Exot 2016 Dec 13;109(5):325-328. Epub 2016 Oct 13.
    Service de pédiatrie, hôpital national de Lamordé, université Abdou-Moumouni-Dioffo, Niamey, Niger.
    We report a fatal case due to a massive attack by a swarm of bees in a nine-year-old child. The accident was fatal because of two aggravating factors: the cephalic location and the large number of stings (about 300). Complications were coagulopathy, anemia, hemorrhage, coma, and oligoanuria. Read More

    Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case-control study.
    BMC Public Health 2016 Sep 29;16(1):1021. Epub 2016 Sep 29.
    INSERM U1169, Hôpital Bicêtre, Université Paris-Sud, Kremlin-Bicêtre, France.
    Background: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the study was to unravel environmental markers associated with T1D.

    Methods: Cases were children with T1D from the French Isis-Diab cohort. Read More

    Honey Bee Swarms Aboard the USNS Comfort: Recommendations for Sting Prevention, Swarm Removal, and Medical Readiness on Military Ships.
    US Army Med Dep J 2016 Oct-Dec(3-16):29-37
    Navy and Marine Corps Public Health Center, Portsmouth, Virginia.
    The article provides observations of multiple honey bee (Apis mellifera) swarms aboard the USNS Comfort (TAH-20) during the Continuing Promise 2015 mission. A brief overview of swarming biology is given along with control/removal recommendations to reduce sting exposures. The observations suggest that preventive medicine personnel should provide adequate risk communications about the potential occurrence of bee swarms aboard military ships, and medical department personnel should be prepared for the possibility of treating of multiple sting exposures, especially in the Southern Command Area of Operations where the Africanized genotype of A mellifera is common. Read More

    Insect Sting Reactions and Specific IgE to Venom and Major Allergens in a General Population.
    Int Arch Allergy Immunol 2016 3;170(3):194-200. Epub 2016 Sep 3.
    Allergy Clinic, Copenhagen University Hospital Gentofte, Hellerup, Denmark.
    Background: Insect sting reactions are frequently reported, but population studies documenting the frequency and the relation to IgE-sensitization and serum tryptase are scarce.

    Methods: Questionnaire data and results from measurements of specific IgE against venom, major allergens and cross-reacting carbohydrate determinants (CCDs) were collected from 2,090 adult participants in a cross-sectional survey.

    Results: 13% of the population reported symptoms of sting reactions and about half were systemic in nature. Read More

    Use of sIgE/T-IgE in Predicting Systemic Reactions: Retrospective Analysis of 54 Honeybee Venom Allergy Cases in North China.
    Chin Med J (Engl) 2016 09;129(17):2091-5
    Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
    Background: Venom allergy is significantly underestimated in China. Venom-specific IgE may not provide accurate clinical reactions. Our conducted retrospective analysis observes alternative diagnostic considerations in assessing confirmation and severity of honeybee venom allergy. Read More

    Specific IgE sensitization to honey bee venom and auto-injector adrenaline prescriptions for Japanese beekeepers.
    Allergol Int 2017 Jan 8;66(1):149-151. Epub 2016 Aug 8.
    Department of Respiratory Medicine and Clinical Immunology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan.

    The correlation between anti phospholipase A2 specific IgE and clinical symptoms after a bee sting in beekeepers.
    Postepy Dermatol Alergol 2016 Jun 17;33(3):206-10. Epub 2016 Jun 17.
    Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Poznan, Poland.
    Introduction: Beekeepers are a group of people with high exposure to honeybee stings and with a very high risk of allergy to bee venom. Therefore, they are a proper population to study the correlations between clinical symptoms and results of diagnostic tests.

    Aim: The primary aim of our study was to assess the correlations between total IgE, venom- and phospholipase A2-specific IgE and clinical symptoms after a bee sting in beekeepers. Read More

    [Not Available].
    Lakartidningen 2016 Aug 4;113. Epub 2016 Aug 4.
    Futurum - Akademin för hälsa och vård - Länssjukhuset Ryhov Jönköping, Sweden Futurum - Akademin för hälsa och vård - Länssjukhuset Ryhov Jönköping, Sweden.
    Bee and wasp stings can cause allergic reactions. Although the local reactions are more frequent, anaphylaxis due to insect stings can be potentially fatal. Rapid recognition of anaphylaxis is therefore critical and reactions should immediately be treated with i. Read More

    Significant Traumatic Intracranial Hemorrhage in the Setting of Massive Bee Venom-Induced Coagulopathy: A Case Report.
    Wilderness Environ Med 2016 Sep 15;27(3):405-8. Epub 2016 Jul 15.
    Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, NY. Electronic address:
    Bees and wasps of the Hymenoptera order are encountered on a daily basis throughout the world. Some encounters prove harmless, while others can have significant morbidity and mortality. Hymenoptera venom is thought to contain an enzyme that can cleave phospholipids and cause significant coagulation abnormalities. Read More

    Multiple bee stings resulting in ST elevation myocardial infarction (the Kounis syndrome).
    Proc (Bayl Univ Med Cent) 2016 Jul;29(3):298-300
    Departments of Emergency Medicine (Pelli, Wieters) and Internal Medicine (Montalvo), Baylor Scott & White Hospital, Temple, Texas; and Texas A&M Medical School (Firozgary).
    Kounis syndrome consists of angina pectoris or myocardial infarction that is triggered by the release of inflammatory mediators in the setting of an allergic reaction. We present the case of a 61-year-old man who presented to the emergency department with anaphylaxis after being stung by >100 bees. During resuscitation, he subsequently developed ST elevation myocardial infarction. Read More

    EPIDEMIOLOGY OF HONEYBEE STING CASES IN THE STATE OF CEARÁ, NORTHEASTERN BRAZIL.
    Rev Inst Med Trop Sao Paulo 2016 24;58:40. Epub 2016 May 24.
    Centro de Educação e Saúde, Universidade Federal de Campina Grande, Paraíba, Brasil.
    In the American continent, honeybee envenomation is a public health problem due to the high incidence and severity of the cases. Despite its medical importance, there is a lack of epidemiological studies on this topic in Brazil, especially referring to the Northeastern states. The present study has aimed to describe the epidemiological features of honeybee envenomation cases in the state of the Ceará, Northeastern Brazil, from 2007 to 2013. Read More

    First Reported Case of Fatal Stinging by the Large Carpenter Bee Xylocopa tranquebarica.
    Wilderness Environ Med 2016 Jun 6;27(2):262-5. Epub 2016 Apr 6.
    Department of Parasitology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka (Dr Weerakoon).
    In the order Hymenoptera, bees, hornets, and wasps are well-known stinging insects whose envenoming can be fatal. Their stinging attacks are common in rural and forested areas of Sri Lanka. However, fatal stinging by the large-bodied carpenter bees is unreported. Read More

    Myocardial infarction following a bee sting: A case report of Kounis syndrome.
    Ann Card Anaesth 2016 Apr-Jun;19(2):375-8
    Department of Emergency Medicine, School of Medicine, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
    In this case report study a 41-year-old man envenomed by a bee sting and diagnosed as Kounis syndrome secondary to hymenoptera envenomation. The patient developed a typical course of myocardial infarction, but the electrocardiogram changes were reversed to almost normal limits. He had a nonsignificant mild lesion in the proximal port of right coronary artery in coronary angiography. Read More

    Safety of Ultrarush Venom Immunotherapy: Comparison Between Children and Adults.
    J Investig Allergol Clin Immunol 2016 ;26(1):40-7
    Background: The ultrarush protocol is an attractive approach in the buildup phase of venom immunotherapy (VIT-UR). However, the degree of risk of VIT-UR in children remains unknown. The objective of this study was to compare the safety of VIT-UR in children and adults. Read More

    Immune and clinical response to honeybee venom in beekeepers.
    Ann Agric Environ Med 2016 ;23(1):120-4
    Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Poland.
    Objective: The aim of the study was to assess immune response to honeybee venom in relation to the degree of exposure, time after a sting and clinical symptoms.

    Materials And Method: Fifty-four volunteers were divided into 2 groups: beekeepers and a control group. The serum levels of total IgE (tIgE), bee venom-specific IgE (venom sIgE), phospholipase A2-specific IgE (phospholipase A2 sIgE), tryptase and venom-specific IgG4 (venom sIgG4) were determined. Read More

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