1,445 results match your criteria Bee Stings

Clinical effects and factors associated with adverse clinical outcomes of hymenopteran stings treated in a Thai Poison Centre: a retrospective cross-sectional study.

Clin Toxicol (Phila) 2021 May 7:1-7. Epub 2021 May 7.

Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Objective: To describe clinical effects and outcomes of hymenopteran stings and to explore the non-laboratory factors associated with adverse clinical outcomes, a composite outcome including death, respiratory failure requiring intubation, acute kidney injury (AKI) requiring dialysis and hypotension requiring vasopressor use.

Methods: A retrospective cross-sectional study was performed at the Ramathibodi Poison Center, a poison centre of a tertiary care hospital in Thailand. All cases of hymenopteran sting consultations from January 2015 to June 2019 were consecutively enrolled, and charts were reviewed. Read More

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In vivo neutralization of bee venom lethality by IgY antibodies.

Mol Immunol 2021 Apr 27;135:183-190. Epub 2021 Apr 27.

Instituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina; Instituto de Patobiología Veterinaria, UEDD INTA-CONICET, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina. Electronic address:

Bee venom is a complex mixture of molecules, among which melittin and phospholipase A (PLA) are the toxic components involved in envenoming accidents with multiple honeybee stings. Traditionally, the treatment of envenomings has been based on the administration of specific antibodies to neutralize the deleterious effects of toxins. An alternative to mammalian polyclonal antibodies is the use of egg yolk immunoglobulins (IgY) due to their advantages regarding animal welfare and lower costs of production as compared to the conventional production methods. Read More

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Delayed Acute Coronary Syndrome Caused by Multiple Bee Stings: A Rare Case of Kounis Syndrome.

Cureus 2021 Mar 26;13(3):e14120. Epub 2021 Mar 26.

Department of Cardiology, University Hospital of Larissa, Larissa, GRC.

A 51-year-old female patient was admitted to our hospital for medical evaluation and treatment of a syncopal episode following multiple bee stings. The syncopal episode was attributed to an allergic reaction and the patient was treated with intravenous hydration and anti-histamines. Twenty-four hours later, the patient manifested an acute coronary syndrome with chest discomfort, electrocardiographic disorders, and myocardial enzyme motility (including troponin). Read More

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[Treatment report of three cases of multiple wasp stings].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2021 Apr;39(4):310-312

Department of Emergency, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

From September to November 2019, three patients with Hornet stings were admitted to hospital with acute anaphylaxis and various degrees of organ dysfunction. After hemoperfusion combined with continuous hemodialysis and hormone pulse therapy, 1 patient was successfully treated and 2 patients were not cured. Bee Stings can cause systemic allergic reactions and toxic reactions. Read More

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Epinephrine Auto-Injection After Allergic Reaction Leading to Gas Gangrene of the Leg.

Am J Case Rep 2021 Apr 21;22:e930889. Epub 2021 Apr 21.

Department of Pharmacy, Mercy Health - St. Elizabeth Youngstown Hospital, Youngstown, OH, USA.

BACKGROUND Clostridial myonecrosis, also known as gas gangrene, is a highly lethal necrotizing soft tissue infection. While commonly associated with trauma, clostridial myonecrosis may be the result of parenteral injection of medications. Epinephrine is the most commonly reported medication leading to gas gangrene. Read More

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Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.

Front Immunol 2021 23;12:653151. Epub 2021 Mar 23.

Department of Infectology, Dermatology, Imaging Diagnosis and Radiotherapy, Botucatu Medical School (FMB), São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, Brazil.

We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee () Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. Participants received 2 to 10 vials of AAV depending on the number of stings they suffered, or a predefined adjuvant, symptomatic, and complementary treatment. The primary safety endpoint was the occurrence of early adverse reactions within the first 24 h of treatment. Read More

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Omalizumab ensures compatibility to bee venom immunotherapy (VIT) after VIT-induced anaphylaxis in a patient with systemic mastocytosis.

Allergol Select 2021 11;5:128-132. Epub 2021 Mar 11.

Interdisciplinary Allergy Outpatient Clinic, Department of Pneumology, University of Luebeck.

Background: Systemic reactions and anaphylaxis due to Hymenoptera venoms occur in up to 7.5% of the European population. Fatal sting reactions are very rare. Read More

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Bienenstich ins Auge!

MMW Fortschr Med 2021 03;163(4):25

FA f. Innere Medizin, München, Deutschland.

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Epidemiology of accidents involving venomous animals in the State of Ceará, Brazil (2007-2019).

Rev Soc Bras Med Trop 2021 10;54:e05112020. Epub 2021 Feb 10.

Universidade Federal do Ceará, Núcleo de Pesquisa e Desenvolvimento de Medicamentos, Laboratório de Farmacologia de Venenos e Toxinas, Fortaleza, CE, Brasil.

Introduction: Envenomation remains a neglected public health problem in most tropical countries. Epidemiological studies on accidents caused by venomous animals are scarce in the Northeast region of Brazil, mainly in the state of Ceará. The present study aimed to describe the epidemiological features of envenomation cases involving venomous animals in the State of Ceará, Northeastern Brazil, from 2007 to 2019. Read More

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February 2021

Understanding the binding mechanism of succinic acid against phospholipase A from bee venom.

J Biochem Mol Toxicol 2021 Apr 13;35(4):e22715. Epub 2021 Feb 13.

Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, Tamil Nadu, India.

Phospholipase A (PLA ) is responsible for the release of fatty acids from glycerophospholipids. PLA is commonly found in mammalian tissues. It is also found in venom from different animals ranging from insects, arachnid, and snakes. Read More

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Deep Vein Thrombosis After a Wild Bee Sting.

J Pediatr Hematol Oncol 2021 Jan 27. Epub 2021 Jan 27.

Departments of Pediatric Hematology Pediatrics Pediatric Infectious Disease, Cukurova University Medical Faculty Department of Radiology, Adana City Training and Research Hospital, Adana, Turkey.

Allergic reactions from insect bites are mostly observed with bee stings. Bee sting reactions can be classified into 3 main headings: local, systemic, and rare reactions. Vascular thrombosis is considered both in rare and systemic reactions. Read More

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January 2021

Human Fatalities Caused by Hornet, Wasp and Bee Stings in Spain: Epidemiology at State and Sub-State Level from 1999 to 2018.

Xesús Feás

Biology (Basel) 2021 Jan 20;10(2). Epub 2021 Jan 20.

Academy of Veterinary Sciences of Galicia, Edificio EGAP, Rúa Madrid, No. 2-4, 15707 Santiago de Compostela (A Coruña), Spain.

Epidemiology of fatalities in Spain due to hornet, wasp, and bee stings (Cause Code of Death: X23) is described. Over a 20-year period (1999-2018), a total of 78 fatalities were recorded, mostly occurring in males (85.9%), of 65 years and older (52. Read More

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January 2021

Venom immunotherapy for Hymenoptera allergy in a dog.

Vet Dermatol 2021 Apr 13;32(2):206-e52. Epub 2021 Jan 13.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 260, Zurich, 8057, Switzerland.

A 1.5-year-old male castrated dog was presented in anaphylactic shock after suffering an apparent bee sting. Immunotherapy with bee venom was initiated based upon history, skin testing and serological testing for allergen-specific immunoglobulin (Ig)E. Read More

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Brachial artery thrombosis following bee sting, case report.

Int J Surg Case Rep 2021 Jan 2;78:184-186. Epub 2020 Dec 2.

Department of Cardiovasculer Surgery, Kırıkkale State Hospital, Yahsihan, Kırıkkale, Turkey.

Introduction: Bee stings are the most common among insect emergencies.

Presentation Of Case: We present a 47-year-old male patient who was admitted to the emergency department with complaints of pallor, chills, numbness and bruising on the left palm one hour after a bee sting on his left leg, and a very rare case of brachial artery stenosis in Dopler ultrasonography.

Discussion: Often bee stings occur only with local allergic reactions; sometimes it can also cause myocardial infarction, pulmonary edema, bleeding, hemolytic anemia, and kidney disease and neurological manifestations. Read More

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January 2021

Prevalence and characteristics of Hymenoptera venom allergy in urban school children aged 6 to 18 years living in Trabzon.

Turk J Med Sci 2020 Dec 28. Epub 2020 Dec 28.

Background: Hymenoptera venom allergy is one of the leading causes of systemic allergic reactions in both adults and children. The present study was conducted to evaluate the prevalence and characteristics of Hymenoptera venom allergy in urban school children aged 6 to 18 years living in Trabzon.

Materials And Methods: In this cross-sectional, two-level survey study, children were recruited using random sampling of public primary and secondary schools. Read More

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December 2020

Bee sting envenomation severe cases in Manaus, Brazilian Amazon: clinical characteristics and immune markers of case reports.

Rev Soc Bras Med Trop 2020 21;54:e20200319. Epub 2020 Dec 21.

Universidade do Estado do Amazonas, Programa de Pós-Graduação em Medicina Tropical, Manaus, AM, Brasil.

Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. Read More

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December 2020

Corneal Bee Sting.

N Engl J Med 2020 Dec 28;383(23):2274. Epub 2020 Nov 28.

Kasturba Medical College Mangalore, Mangalore, India

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December 2020

Management of Secondary Keratouveitis in a Wasp Sting Patient in a Jungle Region of Peru.

Int Med Case Rep J 2020 20;13:663-666. Epub 2020 Nov 20.

Department of Ophthalmology, Research Department Clinica La Luz, Lima, Peru.

Wasp stings are considered an ophthalmological emergency as they can be complicated when they occur near the eyelids or especially on the cornea. Due to type I hypersensitivity response, such as epithelial defect, corneal edema, loss of endothelial cells, anterior uveitis, optic neuritis and, therefore, permanent loss of vision due to anterior segment ischemia. It warns that the wasp stinger has a saw-shaped texture, contains toxins that inflame the area where it stings. Read More

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November 2020

Corneal bee sting: improvement in the acute stage in the absence of treatment.

Pan Afr Med J 2020 14;37:54. Epub 2020 Sep 14.

Penn State College of Medicine, Hershey, Pennsylvania.

Bee sting injuries to the eye are relatively uncommon. The outcomes of corneal bee sting injuries are highly variable, and there is no consensus on the management at the time of initial presentation. We report a case of a 17-year-old male with a corneal bee sting injury that significantly improved in the acute stage without any treatment, which to the best of our knowledge is the first report in the literature documenting the natural history of a corneal bee sting injury in the acute stage. Read More

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January 2021

[Wasp and bee stings with serious consequences].

Ned Tijdschr Geneeskd 2020 11 12;164. Epub 2020 Nov 12.

Tergooi, afd. Intensive Care, Hilversum/Blaricum.

Wasp and bee stings can lead to allergic reactions, anaphylaxis, Kounis syndrome, toxicity, organ failure and, in rare cases, cardiac arrest. In the Netherlands, fatal complications as a result of wasp or bee stings are rare; here we describe three recent severe cases. We diagnosed two patients with anaphylactic shock due to multiple wasp stings, resulting in cardiac arrest and death. Read More

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November 2020

Corneal bee sting in a Bengal cat.

JFMS Open Rep 2020 Jul-Dec;6(2):2055116920962431. Epub 2020 Oct 28.

Saint-Martin Hospital Veterinary Centre, Saint Martin Bellevue, France.

Case Summary: A 6-month-old female Bengal cat was referred for a suspected vegetal foreign body (FB) in the mid-stroma of the right cornea. A small dark linear FB was identified in the dorsal aspect of the cornea, with associated cell infiltrate. Ophthalmic examination was otherwise normal, with no inflammatory reaction of the anterior uvea, and no abnormalities of the lens or fundus. Read More

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October 2020

Anaphylaxis-related hemoperitoneum in 11 dogs.

J Vet Emerg Crit Care (San Antonio) 2021 Jan 29;31(1):80-85. Epub 2020 Oct 29.

Hill Country Veterinary Specialists, Spicewood, TX.

Objective: To describe the unique complication of hemoperitoneum associated with anaphylaxis.

Design: Retrospective case series from September 2012 to August 2017.

Setting: Two private emergency and specialty referral hospitals. Read More

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January 2021

Beekeepers who tolerate bee stings are not protected against SARS-CoV-2 infections.

Toxicon 2020 Nov 6;187:279-284. Epub 2020 Oct 6.

Ortenau Klinikum Offenburg-Kehl, Ebertplatz 12, 77654, Offenburg, Germany. Electronic address:

A survey on 5115 beekeepers and 121 patients treated with bee venom by an apitherapy clinic in the Hubei province, the epicenter of COVID-19 in China, reported that none of the beekeepers developed symptoms associated with COVID-19, the new and devastating pandemic. The hypothesis that immunity to bee venom could have a preventive effect was expressed and the authors of the Chinese survey suggested that the next step should be animal experiments on monkeys. We believed that before starting such studies, a second independent survey should verify the findings and define the hypothesis more clearly. Read More

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November 2020

The effect of hymenoptera venom immunotherapy on neutrophils, interleukin 8 (IL-8) and interleukin 17 (IL-17).

Int J Occup Med Environ Health 2020 Oct 30;33(6):811-817. Epub 2020 Sep 30.

Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland (Department of Allergology, Clinical Immunology and Internal Diseases).

Objectives: Venom immunotherapy (VIT) is an effective treatment method and is addressed to patients with a history of an anaphylactic reaction to Hymenoptera stings. However, the immunological mechanisms of protection have not been explained yet. The objective of this study was to analyze neutrophils, interleukin 8 (IL-8) and interleukin 17 (IL-17) before and after the initial phase of the immunotherapy. Read More

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October 2020

Sensitization to Hymenoptera venom in pollen allergic patients: Frequency and involvement of cross-reacting carbohydrate determinants (CCD).

PLoS One 2020 8;15(9):e0238740. Epub 2020 Sep 8.

Department of Rheumatology, Immunology and Allergology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Sensitization to Hymenoptera venom in patients without a history of systemic allergic reactions to Hymenoptera stings is frequently found and can be due to the presence of specific IgE to cross-reactive carbohydrate determinants (CCD). This study investigates 105 pollen allergic subjects for the presence of specific IgE to honeybee or wasp venom, pollen, the MUXF3 carbohydrate epitope from bromelain and recombinant Hymenoptera venom components. In addition, in a subgroup of patients (n = 10) a basophil activation test (BAT) using bee and wasp venom was performed. Read More

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November 2020

A Case Report on Rhabdomyolysis After Multiple Bee Stings.

Cureus 2020 Jul 31;12(7):e9501. Epub 2020 Jul 31.

Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, USA.

Envenoming syndrome is an uncommon condition associated with significant morbidity and mortality following multiple Hymenoptera stings. We review the case of a 90-year-old male who presented after receiving greater than 100 bee stings and was found to have rhabdomyolysis with concomitant acute kidney injury. Physicians should consider envenoming syndrome in all patients presenting with greater than 50 bee stings, despite hemodynamically stability upon initial presentation. Read More

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Clinical Effectiveness and Adverse Events of Bee Venom Therapy: A Systematic Review of Randomized Controlled Trials.

Toxins (Basel) 2020 08 29;12(9). Epub 2020 Aug 29.

Department of Preventive Medicine, College of Korean Medicine, Woosuk University, Jeonju 54986, Jeollabuk-do, Korea.

Bee venom has been used to treat many diseases because of its anti-inflammatory and analgesic effects. However, the secretions of bee venom can also cause life-threatening adverse reactions. The objective of this paper was to review the clinical effectiveness of bee venom and adverse events induced by bee venom, regardless of the disease. Read More

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Parvovirus Infection in a Child Presenting with Erythema Multiforme and Vasculitis after a Yellow Jacket Bee Sting.

J Trop Pediatr 2020 Jul 10. Epub 2020 Jul 10.

Department of Pediatric Nephrology, Trakya University Faculty of Medicine, Edirne, Turkey.

Parvovirus B19 has a wide spectrum of clinical manifestations. Erythema multiforme and vasculitis are rarely reported with parvovirus B19 infections. Reactions to insect stings can range from local swelling to life-threatening systemic reactions. Read More

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Envenomations during pregnancy reported to the national poison data system, 2009-2018.

Toxicon 2020 Oct 6;186:78-82. Epub 2020 Aug 6.

New Mexico Poison Center, University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Department of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. Electronic address:

Envenomations during pregnancy have consequences affecting both maternal and fetal outcomes. U.S. Read More

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October 2020

Editorial: Novel Immunotherapies Against Envenomings by Snakes and Other Venomous Animals.

Front Immunol 2020 22;11:1004. Epub 2020 May 22.

Departamento de Bioquímica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

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