31,116 results match your criteria Bedside Ultrasonography Cardiac Evaluation

Automated detection of artefacts in neonatal EEG with residual neural networks.

Comput Methods Programs Biomed 2021 May 24;208:106194. Epub 2021 May 24.

Brain Modelling Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia; BaBA center, Department of Children's Clinical Neurophysiology, Children's hospital, HUS Medical Imaging center, Helsinki University Central Hospital and University of Helsinki, Finland. Electronic address:

Background And Objective: To develop a computational algorithm that detects and identifies different artefact types in neonatal electroencephalography (EEG) signals.

Methods: As part of a larger algorithm, we trained a Residual Deep Neural Network on expert human annotations of EEG recordings from 79 term infants recorded in a neonatal intensive care unit (112 h of 18-channel recording). The network was trained using 10 fold cross validation in Matlab. Read More

View Article and Full-Text PDF

Exploring family members' and health care professionals' perceptions on ICU diaries: a systematic review and qualitative data synthesis.

Intensive Care Med 2021 Jun 12. Epub 2021 Jun 12.

Intensive Care Unit of the Hospital da Mulher, Rua Barão de Cotegipe, 1153, Roma, Salvador, BA, 40411-900, Brazil.

Purpose: Although the intensive care unit (ICU) diary has been proposed as a tool for preventing psychiatric symptoms in survivors of critical illness, relatives and health care providers may benefit from it too. This study aims to summarize the current qualitative evidence on families' and health care professionals' experiences of writing in and reading the ICU diaries.

Methods: We searched MEDLINE, OVID, Embase, and EBSCOhost from inception to February 2021, and included all the studies that presented any qualitative finding regarding relatives' and health care providers' experiences of writing in and reading an ICU diary. Read More

View Article and Full-Text PDF

Lung ultrasound score based on the BLUE-plus protocol is associated with the outcomes and oxygenation indices of intensive care unit patients.

J Clin Ultrasound 2021 Jun 11. Epub 2021 Jun 11.

Department of Critical Care Medicine, Xiangya Hospital, Central South University, National Clinical Research Center for Geriatric Disorders, Hunan Provincial Clinical Research Center for Critical Care Medicine, Changsha, Hunan Province, China.

Purpose: The primary objective was to demonstrate the relationship between lung ultrasound (LUS) manifestations and the outcomes of intensive care unit (ICU) patients. The secondary objective was to determine the characteristics of LUS manifestations in different subgroups of ICU patients.

Methods: This prospective multi-center cohort study was conducted in 17 ICUs. Read More

View Article and Full-Text PDF

Discordance Between Respiratory Drive and Sedation Depth in Critically Ill Patients Receiving Mechanical Ventilation.

Crit Care Med 2021 Jun 9. Epub 2021 Jun 9.

Center for Acute Respiratory Failure, Columbia University College of Physicians and Surgeons and New York-Presbyterian Hospital, New York, NY. Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Taibah University, Medina, Saudi Arabia. Department of Pharmacy, UC San Diego Health, San Diego, CA. Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY.

Objectives: In mechanically ventilated patients, deep sedation is often assumed to induce "respirolysis," that is, lyse spontaneous respiratory effort, whereas light sedation is often assumed to preserve spontaneous effort. This study was conducted to determine validity of these common assumptions, evaluating the association of respiratory drive with sedation depth and ventilator-free days in acute respiratory failure.

Design: Prospective cohort study. Read More

View Article and Full-Text PDF

Step-by-step inpatient rehabilitation for critical illness after coronavirus disease 2019: A CARE-compliant case report.

Medicine (Baltimore) 2021 Jun;100(23):e26317

Department of Rehabilitation Medicine, Kyungpook National University Hospital.

Introduction: Since the coronavirus disease (COVID-19) outbreak in Wuhan, China, in December 2019, COVID-19 has become a worldwide pandemic. Muscle weakness and deconditioning caused by COVID-19-induced critical illness requires rehabilitation.

Patient Concerns: A 74-year-old male patient complained of general weakness after COVID-19, requiring ventilator treatment. Read More

View Article and Full-Text PDF

Multimodality imaging of the ischemic right ventricle: an overview and proposal of a diagnostic algorithm.

Int J Cardiovasc Imaging 2021 Jun 10. Epub 2021 Jun 10.

Department of Cardiovascular Diseases, University of Siena, Siena, Italy.

Right ventricular (RV) involvement is frequently detected in patients presenting with acute left ventricular myocardial infarction. The ischemic right ventricle carries a dismal outcome by predisposing the heart to arrhythmic events and mechanical or hemodynamic complications. A comprehensive RV evaluation by multimodality imaging could guide clinical practice but has always been a conundrum for the imagers. Read More

View Article and Full-Text PDF

Long QT syndrome - Bench to bedside.

Heart Rhythm O2 2021 Feb 22;2(1):89-106. Epub 2021 Jan 22.

Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio.

Long QT syndrome (LQTS) is a cardiovascular disorder characterized by an abnormality in cardiac repolarization leading to a prolonged QT interval and T-wave irregularities on the surface electrocardiogram. It is commonly associated with syncope, seizures, susceptibility to torsades de pointes, and risk for sudden death. LQTS is a rare genetic disorder and a major preventable cause of sudden cardiac death in the young. Read More

View Article and Full-Text PDF
February 2021

Lung Ultrasound Score as a Predictor of Mortality in Patients With COVID-19.

Front Cardiovasc Med 2021 25;8:633539. Epub 2021 May 25.

Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Lung injury is a common condition among hospitalized patients with coronavirus disease 2019 (COVID-19). However, whether lung ultrasound (LUS) score predicts all-cause mortality in patients with COVID-19 is unknown. The aim of the present study was to explore the predictive value of lung ultrasound score for mortality in patients with COVID-19. Read More

View Article and Full-Text PDF

[Application progress of ultrasound monitoring of diaphragm function in clinic].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 May;33(5):638-640

Department of Anesthesiology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.

In recent years, point of care ultrasound (POCUS) has developed rapidly in the fields of anesthesia and critical care. POCUS is widely used in clinic to monitor the function of human tissues and organs such as the heart, lungs, and diaphragm due to its visual, non-invasive, portable, and repeatable characters at the bedside. Diaphragm is an important structure to maintain respiratory function. Read More

View Article and Full-Text PDF

Early recovery of frontal EEG slow wave activity during propofol sedation predicts outcome after cardiac arrest.

Resuscitation 2021 Jun 7. Epub 2021 Jun 7.

Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Aim Of The Study: EEG slow wave activity (SWA) has shown prognostic potential in post-resuscitation care. In this prospective study, we investigated the accuracy of continuously measured early SWA for prediction of the outcome in comatose cardiac arrest (CA) survivors.

Methods: We recorded EEG with a disposable self-adhesive frontal electrode and wireless device continuously starting from ICU admission until 48 h from return of spontaneous circulation (ROSC) in comatose CA survivors sedated with propofol. Read More

View Article and Full-Text PDF

Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease.

Circ Res 2021 Jun 10;128(12):1927-1943. Epub 2021 Jun 10.

Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, CA (T.A., N.J.L.).

Peripheral arterial disease is a growing worldwide problem with a wide spectrum of clinical severity and is projected to consume >$21 billion per year in the United States alone. While vascular researchers have brought several therapies to the clinic in recent years, few of these approaches have leveraged advances in high-throughput discovery screens, novel translational models, or innovative trial designs. In the following review, we discuss recent advances in unbiased genomics and broader omics technology platforms, along with preclinical vascular models designed to enhance our understanding of disease pathobiology and prioritize targets for additional investigation. Read More

View Article and Full-Text PDF

Pressure ulcer risk assessment-registered nurses´ experiences of using PURPOSE T: A focus group study.

J Clin Nurs 2021 Jun 9. Epub 2021 Jun 9.

Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.

Aim: To evaluate the clinical usability of PURPOSE T among registered nurses in Sweden.

Background: Pressure ulcers are an adverse event and a problem worldwide. Risk assessment is a cornerstone, and a first step in pressure ulcer prevention is to identify possible risk patients and/or pressure ulcers. Read More

View Article and Full-Text PDF

Use of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Analysis of Serum Peptidome to Classify and Predict Coronavirus Disease 2019 Severity.

Open Forum Infect Dis 2021 Jun 2;8(6):ofab222. Epub 2021 May 2.

Servicios Científico-Técnicos, Universidad de las Islas Baleares, Palma de Mallorca, Spain.

Background: Classification and early detection of severe coronavirus disease 2019 (COVID-19) patients is required to establish an effective treatment. We tested the utility of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) to classify and predict the severity of COVID-19.

Methods: We used MALDI-TOF MS to analyze the serum peptidome from 72 patients with COVID-19 (training cohort), clinically classified as mild (28), severe (23), and critical (21), and 20 healthy controls. Read More

View Article and Full-Text PDF


J Trauma Acute Care Surg 2021 Apr 8. Epub 2021 Apr 8.

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, CA.

Background: Focused Assessment with Sonography for Trauma (FAST) has supplanted Diagnostic Peritoneal Lavage (DPL) as the preferred bedside evaluation for traumatic hemoperitoneum. Diagnostic Peritoneal Aspiration (DPA) is a simpler, faster modification of DPL with an unclear role in contemporary practice. This study delineated modern roles for DPA and defined its diagnostic yield. Read More

View Article and Full-Text PDF

An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke.

Sci Transl Med 2021 Jun;13(597)

Translational Research Institute of Brain and Brain-Like Intelligence and Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, Tongji University School of Medicine, Shanghai 200434, China.

Studies have failed to translate more than 1000 experimental treatments from bench to bedside, leaving stroke as the second leading cause of death in the world. Thrombolysis within 4.5 hours is the recommended therapy for stroke and cannot be performed until neuroimaging is used to distinguish ischemic stroke from hemorrhagic stroke. Read More

View Article and Full-Text PDF

Early diagnosis of mortality using admission CT perfusion in severe traumatic brain injury patients (ACT-TBI): protocol for a prospective cohort study.

BMJ Open 2021 Jun 9;11(6):e047305. Epub 2021 Jun 9.

Department of Radiology, University of Manitoba Faculty of Health Sciences, Winnipeg, Manitoba, Canada

Introduction: Severe traumatic brain injury (TBI) is a catastrophic neurological condition with significant economic burden. Early in-hospital mortality (<48 hours) with severe TBI is estimated at 50%. Several clinical examinations exist to determine brain death; however, most are difficult to elicit in the acute setting in patients with severe TBI. Read More

View Article and Full-Text PDF

[Abdominal Pain Caused by Viral Infection Is Not Always Trivial].

Praxis (Bern 1994) 2021 Jun;110(8):449-451

Zentrale Notaufnahme, Departement Interdisziplinäre Dienste, Kantonsspital St. Gallen, St. Gallen.

Abdominal Pain Caused by Viral Infection Is Not Always Trivial We report on a 28-year-old previously healthy patient with initially elevated temperature and cough and developing most severe epigastric pain and peritonism in the right upper abdomen. A "bedside" sonography revealed a portal vein thrombosis, the CT additionally partial thromboses of the vena lienalis, vena mesenterica superior. During the examination, a SARS-CoV-2 infection (IgM, IgG) was confirmed. Read More

View Article and Full-Text PDF

Closed-loop artificial endocrine pancreas from Japan.

Artif Organs 2021 Jun 9. Epub 2021 Jun 9.

Departments of Surgery, Kochi Medical School, Kochi University, Kochi, Japan.

The development of a closed-loop artificial pancreas (AP) in the Western countries and Japan is different. In Western countries, wearable AP with a closed-loop glycemic control system has been developed as a treatment for patients with type 1 and type 2 diabetes. On the contrary, in Japan, bedside closed-loop AP explored by a Japanese company (Nikkiso, Tokyo, Japan) has developed as perioperative glycemic control device in surgical patients and acute care patients with emergency. Read More

View Article and Full-Text PDF

Canadian Airway Focus Group updated consensus-based recommendations for management of the difficult airway: part 2. Planning and implementing safe management of the patient with an anticipated difficult airway.

Can J Anaesth 2021 Jun 8. Epub 2021 Jun 8.

Department of Anesthesia & Perioperative Medicine, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, University of Western Ontario, 339 Windermere Rd., LHSC- University Hospital, London, ON, N6A 5A5, Canada.

Purpose: Since the last Canadian Airway Focus Group (CAFG) guidelines were published in 2013, the published airway management literature has expanded substantially. The CAFG therefore re-convened to examine this literature and update practice recommendations. This second of two articles addresses airway evaluation, decision-making, and safe implementation of an airway management strategy when difficulty is anticipated. Read More

View Article and Full-Text PDF

Contrast echocardiography facilitates appropriate management of hospitalized patients with coronavirus disease 2019 (COVID-19) and suspected right ventricular masses: case series.

Eur Heart J Case Rep 2021 Mar 10;5(3):ytaa575. Epub 2021 Mar 10.

Northwick Park Hospital, Department of Cardiology and Cardiac Research Charity, Northwick Park Hospital, Harrow, UK.

Background: Coronavirus disease 2019 (COVID-19) infection is associated with a coagulopathy with high incidence of venous thrombo-embolism. However, bleeding risk is also significant, causing difficulty in initiating and adjusting anticoagulation therapy in case of suspected thrombi. Cardiac masses can be challenging to be identified properly in the context of this disease. Read More

View Article and Full-Text PDF

Rapid Intensive Care Unit Onboarding in Response to a Pandemic.

J Med Educ Curric Dev 2021 Jan-Dec;8:23821205211020741. Epub 2021 May 31.

Division of Pulmonary & Critical Care Medicine, Baystate Medical Center and University of Massachusetts Medical School, Springfield, MA, USA.

Background: In the wake of the coronavirus disease 2019 (COVID-19) pandemic, hospital resources have been stretched to their limits. We introduced an innovative course to rapidly on-board a group of non-intensive care unit (ICU) nurse practitioners as they begin to practice working in a critical care setting.

Objective: To assess whether a brief educational course could improve non-ICU practitioners' knowledge and comfort in practicing in an intensive care setting. Read More

View Article and Full-Text PDF

Massive Pulmonary Embolism and Deep Vein Thrombosis in COVID-19 Pneumonia: Two Case Reports.

Cureus 2021 May 4;13(5):e14833. Epub 2021 May 4.

Diagnostic Radiology, St. Joseph Mercy Oakland Hospital, Pontiac, USA.

Coronavirus disease 2019 (COVID-19) is known to cause a severe acute respiratory syndrome with increased morbidity and mortality due to multiorgan involvement. COVID-19 is associated with an increased risk of venous thromboembolism (VTE), ranging from asymptomatic to potentially fatal presentations. Predictors of VTE in COVID-19 are not fully defined, and the role of anticoagulation in these patients is debatable. Read More

View Article and Full-Text PDF

Early diagnosis of diaphragm palsy after pediatric cardiac surgery and outcome after diaphragm plication - A single-center experience.

Ann Pediatr Cardiol 2021 Apr-Jun;14(2):178-186. Epub 2021 Feb 16.

Department of Cardiovascular and Thoracic Surgery, U.N. Mehta Institute of Cardiology and Research Center, Ahmedabad, Gujarat, India.

Objective: The aims of our prospective observational study were to evaluate the (1) reliability of clinical signs in the early detection of diaphragm palsy (DP); (2) reliability of ultrasonography using echo machine as a bedside tool for the diagnosis of DP; and (3) does early diaphragm plication result in the improved outcome? We also sought to determine the incidence and predominant risk factors for DP and diaphragm plication at our center.

Materials And Methods: This prospective observational study included patients with suspected DP from January 2015 to December 2018. Patients with suspected DP were initially evaluated by bedside ultrasonography using echo machine and confirmed by fluoroscopy. Read More

View Article and Full-Text PDF
February 2021

Surgical Site Infections and Inflammatory Reaction After Cardiac Surgery; Bedside Artificial Pancreas Versus Conventional Insulin Therapy: A Propensity Score-Matched Analysis.

J Cardiothorac Vasc Anesth 2021 May 12. Epub 2021 May 12.

Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Objectives: Perioperative hyperglycemia is associated with poor postoperative recovery, including compromised immune function and increased risk of infection. A closed-loop glycemic control system (artificial pancreas) has demonstrated strict safe perioperative glycemic control without hypoglycemia risk. The authors hypothesized that the artificial pancreas would reduce surgical site infections (SSIs) and postoperative inflammatory reactions. Read More

View Article and Full-Text PDF

Contrast-Enhanced Ultrasound in Small Intestinal Ischemia: Proof of Concept.

J Ultrasound Med 2021 Jun 8. Epub 2021 Jun 8.

Department of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Background: Small intestinal ischemia is a challenging diagnosis to make, even with the combination of imaging, laboratory analysis, and physical exam. This pilot study investigated the role of CEUS in evaluating small bowel wall vascularity in participants with suspected ischemia.

Methods: In this IRB-approved pilot study, CEUS using perflutren lipid microspheres (DEFINITY®; Lantheus Medical Imaging Inc. Read More

View Article and Full-Text PDF

Peripheral vascular disease: Preclinical models and emerging therapeutic targeting of the vascular endothelial growth factor ligand-receptor system.

Expert Opin Ther Targets 2021 Jun 8. Epub 2021 Jun 8.

Dept of Medicine and Vascular Biology Center, Augusta University, USA.

Introduction: Vascular endothelial growth factor (VEGF)-A is a sought therapeutic target for the treatment of PAD because of its potent role in angiogenesis. However, no therapeutic benefit was achieved in VEGF-A clinical trials, suggesting that our understanding of VEGF-A biology and ischemic angiogenic processes needs development. Alternate splicing in VEGF-A produces pro- and anti-angiogenic VEGF-A isoforms; the only difference being a 6-amino acid switch in the C-terminus of the final 8 exon of the gene. Read More

View Article and Full-Text PDF

Are we fit to teach? A survey in physicians of the in- and outpatient departments of internal medicine at a Swiss university hospital.

Swiss Med Wkly 2021 May 7;151:w20505. Epub 2021 Jun 7.

Division of Internal Medicine, University Hospital Basel and University of Basel, Switzerland.

Aim Of The Study: Teaching is one of the three pillars of medical-academic activity, alongside patient care and research. The aim of our study was to assess current teaching practice in the medical departments of the University Hospital Basel, Switzerland, in order to organise a faculty development programme tailored to local needs.

Methods: We performed a cross-sectional online survey among the teaching faculty and the residents. Read More

View Article and Full-Text PDF

Seemingly inconsequential yet catastrophic: the importance of wound washout with minute depressed skull fracture from a dog bite.

Childs Nerv Syst 2021 Jun 7. Epub 2021 Jun 7.

Section of Pediatric Neurosurgery, Department of Neurological Surgery, Riley Hospital for Children, Indiana University School of Medicine, 705 Riley Hospital Drive, Rm 1601C, Indianapolis, IN, 46202, USA.

Depressed skull fractures from dog bites are common pediatric head injuries which are contaminated with native skin and canine oral flora. Outcomes can potentially be catastrophic. Thus, these injuries require proper initial management to prevent future complications. Read More

View Article and Full-Text PDF

The assessment of cognitive and behavioural disturbances in vascular cognitive impairment (VCI) - recommendations of an expert working group.

Neurol Neurochir Pol 2021 Jun 7. Epub 2021 Jun 7.

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

With newer research-based classification systems, the term Vascular Cognitive Impairment (VCI) is now preferred to vascular dementia. VCI is an umbrella term that includes all forms of cognitive deficits ranging from mild cognitive impairment of vascular origin (VaMCI) to vascular dementia (VaD). The new VCI construct takes into account the fact that in addition to single strategic infarcts, multiple infarcts, and leukoaraiosis, there are other mechanisms of cerebrovascular disease such as chronic hypoperfusion that might account for the pattern of cognitive deficits associated with vascular dementia. Read More

View Article and Full-Text PDF