Matrix Metalloproteinases Are Differentially Regulated and Responsive to Compression Therapy in a Red Duroc Model of Hypertrophic Scar.
- Taryn E Travis,
- Pejhman Ghassemi,
- Nicholas J Prindeze,
- Lauren T Moffatt,
- Bonnie C Carney,
- Abdulnaser Alkhalil,
- Jessica C Ramella-Roman,
- Jeffrey W Shupp
Eplasty 2018 5;18:e1. Epub 2018 Jan 5.
The Burn Center, Department of Surgery, MedStar Washington Hospital Center, Washington, DC.
Proteins of the matrix metalloproteinases family play a vital role in extracellular matrix maintenance and basic physiological processes in tissue homeostasis. The function and activities of matrix metalloproteinases in response to compression therapies have yet to be defined. Here, a swine model of hypertrophic scar was used to profile the transcription of all known 26 matrix metalloproteinases in scars treated with a precise compression dose. Read More