Ophthalmic Plast Reconstr Surg 2021 Jan 19. Epub 2021 Jan 19.
Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania; Department of Oculoplastics, Wills Eye Hospital, Philadelphia, Pennsylvania Department of Ocular Pathology, Wills Eye Hospital, Philadelphia, Pennsylvania.
Carcinosarcoma is a malignant mixed tumor composed of epithelial and mesenchymal components which arises in a variety of tissues, including, in rare cases, the orbit. A 75-year-old male with a history of basal cell carcinoma of the left medial canthus, previously treated with surgical resection and adjuvant radiation therapy, presented with a recurrent 3 cm nodule of the left medial canthus. He underwent surgical resection of the left superior and inferior eyelid with pathology revealing invasive squamous cell carcinoma of upper and lower eyelids with deep orbital tissue involvement and undifferentiated pleomorphic sarcoma involving the dermis and periosteum, consistent with carcinosarcoma. Read More