5,319 results match your criteria Basal Cell Carcinoma* Dermatology


Matrical Carcinoma with Melanocytic Hyperplasia Mimicking Nodular Melanoma in an Elderly Mexican Male.

J Cutan Pathol 2019 Feb 20. Epub 2019 Feb 20.

Department of Dermatology, University of California, Irvine.

Matrical carcinoma with melanocytic hyperplasia (MCMH), previously referred to as malignant melanocytic matricoma, is a rare variant of the uncommon pilomatrical carcinoma, which occurs most often on the head/neck and upper backs of middle-aged men. Nodular lesions may resemble pigmented basal cell carcinoma or melanoma clinically. We present a case of MCMH in a Hispanic patient with history of melanoma. Read More

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http://dx.doi.org/10.1111/cup.13445DOI Listing
February 2019

Nodular Cystic Variant of Basal Cell Carcinoma: Perfect Correlation Between Histopathology and Confocal Microscopy.

Dermatol Pract Concept 2019 Jan 31;9(1):67-68. Epub 2019 Jan 31.

Department of Dermatology and Venereology, Hospital Universitario Fundación Alcorcón, Madrid, Spain.

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http://dx.doi.org/10.5826/dpc.0901a15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368071PMC
January 2019

Vulvar basal cell carcinoma: clinical features and treatment outcomes from a tertiary-care centre.

Singapore Med J 2019 Feb 18. Epub 2019 Feb 18.

Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore.

We retrospectively reviewed the clinical features, management and outcomes of patients diagnosed with basal cell carcinoma (BCC) of the vulva at the Gynaecological Cancer Centre, KK Women's and Children's Hospital, Singapore, between 1 January 2000 and 28 February 2014. Patients with vulvar BCC were identified from the cancer registry, and their medical records reviewed and analysed. A total of 11 patients with vulvar BCC were identified. Read More

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http://dx.doi.org/10.11622/smedj.2019014DOI Listing
February 2019

Insight into Imiquimod Skin Permeation and Increased Delivery Using Microneedle Pre-treatment.

Eur J Pharm Biopharm 2019 Feb 13. Epub 2019 Feb 13.

Division of Advanced Materials and Healthcare Technologies, School of Pharmacy, The University of Nottingham, NG7 2RD, UK. Electronic address:

Basal cell carcinoma (BCC) is the most common skin cancer in humans. Topical treatment with imiquimod provides a non-invasive, self-administered treatment with relatively low treatment cost. Despite displaying excellent efficacy, imiquimod is only licensed by the FDA for superficial BCC. Read More

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http://dx.doi.org/10.1016/j.ejpb.2019.02.006DOI Listing
February 2019
1 Read

Live remote control of an in vivo reflectance confocal microscope allows diagnosis of basal cell carcinoma at the bedside on a patient 2,500 miles away: A novel tele-RCM approach.

J Am Acad Dermatol 2019 Feb 13. Epub 2019 Feb 13.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.02.016DOI Listing
February 2019
1 Read

Successful Utilization of Optical Coherence Tomography as a Non-Invasive, Bedside Imaging Technique To Identify Residual Nodular Basal Cell Carcinoma at Well-Healed and Clinically Unidentifiable Biopsy Site.

J Am Acad Dermatol 2019 Feb 13. Epub 2019 Feb 13.

Laser & Skin Surgery Center of New York, New York, NY; The Ronald O. Perelman Department of Dermatology, New York University, New York, NY.

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http://dx.doi.org/10.1016/j.jaad.2019.02.012DOI Listing
February 2019

A 14-year review of a UK teledermatology service: experience of over 40 000 teleconsultations.

Clin Exp Dermatol 2019 Feb 14. Epub 2019 Feb 14.

Medway NHS Foundation Trust, Gillingham, Kent, UK.

Background: There is a paucity of published evidence of established teledermatology (TD) services in the UK. An in-house TD service using store-and-forward technology was set up at a large regional dermatology department in 2004.

Aim: To review the TD service at our centre, including teleconsultation numbers, coding of diagnoses and patient outcomes. Read More

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http://dx.doi.org/10.1111/ced.13928DOI Listing
February 2019

S2k Guidelines for Cutaneous Basal Cell Carcinoma - Part 2: Treatment, Prevention and Follow-up.

J Dtsch Dermatol Ges 2019 Feb;17(2):214-230

Department of Dermatology, Mainz University Medical Center, Mainz, Germany.

Basal cell carcinoma (BCC) is the most common malignant tumor among fair-skinned individuals, and its incidence had been steadily rising in the past decades. In order to maintain the highest quality of patient care possible, the German S2k guidelines were updated following a systematic literature search and with the participation of all professional societies and associations involved in the management of the disease. Part 2 addresses issues such as proper risk stratification, the various therapeutic approaches, and prevention as well as follow-up of patients with basal cell carcinoma. Read More

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http://doi.wiley.com/10.1111/ddg.13755
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http://dx.doi.org/10.1111/ddg.13755DOI Listing
February 2019
3 Reads

Algorithms for ascertaining keratinocyte carcinomas using health insurance claims and prescription records.

J Eur Acad Dermatol Venereol 2019 Feb 14. Epub 2019 Feb 14.

Department of Dermatology and Skin Science, University of British Columbia.

Skin cancer is the most common human malignancy with an ongoing continual increase in global incidence. Despite their high prevalence, keratinocyte carcinomas (KCs), namely basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are often excluded from population-based cancer registries. As there are over 3000 defined skin disease varieties that can be diagnosed, robust ascertainment methods are needed to capture KC cases for epidemiologic purposes. Read More

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http://dx.doi.org/10.1111/jdv.15490DOI Listing
February 2019

Locally destructive metastatic basal cell carcinoma.

Cutis 2019 Jan;103(1):E23-E25

Department of Dermatology, College of Medicine, Texas AM Health Science Center, and Baylor Scott and White Health, Temple, USA.

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January 2019

Diagnosis and Management of Basal Cell Carcinoma.

Authors:
Keiji Tanese

Curr Treat Options Oncol 2019 Feb 11;20(2):13. Epub 2019 Feb 11.

Department of Dermatology, Keio University School of Medicine, Shinanomachi 35, Shinjuku, Tokyo, 160-8582, Japan.

Opinion Statement: Basal cell carcinomas (BCCs) are common skin cancers that tend to appear on sun-exposed skin. Pathobiologically, activation of the Hedgehog signaling pathway characterizes the majority of cases. In general, BCCs are slow-growing and rarely metastasize. Read More

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http://link.springer.com/10.1007/s11864-019-0610-0
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http://dx.doi.org/10.1007/s11864-019-0610-0DOI Listing
February 2019
2 Reads

PRISModegib: the use of the PRISM test to assess the Health-Related Quality of Life of patients with Locally Advanced Basal Cell Carcinoma undergoing Hedgehog Pathway Inhibitor Therapy.

Br J Dermatol 2019 Feb 9. Epub 2019 Feb 9.

Department of Dermatology, ASST degli Spedali Civili, Spedali Civili di Brescia, Brescia, Italy.

Vismodegib is an Hedgehog Pathway Inhibitor Therapy (HPIT) for patients affected by Locally Advanced Basal Cell Carcinoma (laBCC) and Metastatic Basal Cell Carcinoma (mBCC) not eligible for surgery and/or radiotherapy . The efficacy of Vismodegib has been reported by several studies; likewise, treatment-emergent adverse effects (AEs) have been reported for 95-100% of the patients . It has been observed that patients who achieved complete or partial response often discontinued HPIT because of a grade 1 or 2 AEs. Read More

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http://dx.doi.org/10.1111/bjd.17754DOI Listing
February 2019

Coffee, tea, caffeine, and risk of non-melanoma skin cancer in a Chinese population: The Singapore Chinese Health Study.

J Am Acad Dermatol 2019 Feb 4. Epub 2019 Feb 4.

Health Services and Systems Research, Duke-NUS Medical School, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address:

Background: While epidemiological studies in populations of European-descent suggest possible chemo-protective effect of caffeine against non-melanoma skin cancer (NMSC), data in Asian populations are lacking.

Objectives: We examined the relations between coffee, tea and caffeine consumption, and NMSC risk among Chinese in Singapore.

Methods: We used data from the Singapore Chinese Health Study, a prospective cohort of 63,257 men and women aged 45-74 years at recruitment from 1993 to 1998. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.01.084DOI Listing
February 2019
1 Read

Cutaneous shrinkage after surgical resection of facial skin tumors: a prospective study on 100 surgical specimens.

Clin Exp Dermatol 2019 Feb 7. Epub 2019 Feb 7.

Aix Marseille University, APHM, Hôpital Nord, Department of Oral and Maxillofacial Surgery, 13015, Marseille, France.

Histological reports of skin tumor excisions frequently describe a lesser margin than the clinical excision margin. This study was aimed to evaluate the degree of shrinkage occurring in facial cutaneous specimens after excision and formalin fixation, and to assess the role of potentially influential factors. Our prospective study on 100 surgical specimens from 06/01/2017 to 10/31/2017 showed a mean shrinkage from in vivo (before excision) to in vitro (after 24h formalin fixation) of 12. Read More

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http://dx.doi.org/10.1111/ced.13945DOI Listing
February 2019

Dermoscopy for the diagnosis of eyelid margin tumours.

Br J Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Ophthalmology, University Hospital of Saint-Etienne, 42055 Saint-Etienne Cedex 2, France.

There are only case reports concerning dermoscopy of eyelid margin tumours. We evaluated the clinical and dermoscopic features of 165 eyelid margin tumours of 145 consecutive patients (77 females, 68 males, mean age 64·3 years, standard deviation - SD 17·94, range 10 - 95 years) recruited at the Dermatology Department of the University Hospital of Saint-Etienne, France, between September 1st, 2013 and January 30th, 2017 to exclude malignant tumours. This article is protected by copyright. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.17743
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http://dx.doi.org/10.1111/bjd.17743DOI Listing
February 2019
2 Reads

Micrographic controlled surgery of basal cell carcinomas - Rapid Lump Examination (RLE) in comparison to H&E-stained paraffin sections.

Br J Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, University Hospital, Liebermeisterstraße 25, D-72076, Tuebingen.

The most common skin cancer is basal cell carcinoma (BCC). As the incidence of BCC is increasing, it is of major interest to optimize diagnostic and therapeutic options. The most effective option for complete clearance is through surgical treatment. Read More

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http://dx.doi.org/10.1111/bjd.17740DOI Listing
February 2019

Patterns of proliferation and apoptosis in different subtypes of basal cell carcinoma, adjacent epidermis, and recurrent forms.

An Bras Dermatol 2019 Jan-Feb;94(1):108-110

Dermatology Course, Department of Dermatology and Radiotherapy, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu (SP), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20198165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360986PMC
February 2018

Study of skin neoplasms in a university hospital: integration of anatomopathological records and its interface with the literature.

An Bras Dermatol 2019 Jan-Feb;94(1):42-46

Service of Dermatology, Hospital Escola Álvaro Alvim, Campos dos Goytacazes (RJ), Brazil.

Background: Skin cancer is a highly prevalent condition with a multifactorial etiology resulting from genetic alterations, environmental and lifestyle factors. In Brazil, among all malignant tumors, skin cancers have the highest incidences.

Objective: To retrospectively evaluate the incidence, prevalence and profile of basal cell carcinoma, squamous cell carcinoma and cutaneous melanoma in Campos dos Goytacazes and region. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20197357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360975PMC
June 2017
1 Read

Mohs Appropriate Use Criteria for Superficial Basal Cell Carcinoma-Reply.

JAMA Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, University of California, Irvine, Irvine, California.

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http://dx.doi.org/10.1001/jamadermatol.2018.5664DOI Listing
February 2019

Mohs Appropriate Use Criteria for Superficial Basal Cell Carcinoma.

Authors:
Jonathan Kantor

JAMA Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1001/jamadermatol.2018.4572DOI Listing
February 2019

Mohs Appropriate Use Criteria for Superficial Basal Cell Carcinoma.

JAMA Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Scientific Advisory Committee, ACMS, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1001/jamadermatol.2018.5661DOI Listing
February 2019

Reply to Woltsche N. et al. Managing adverse effects by dose reduction during routine treatment of locally advanced basal cell carcinoma with the hedgehog inhibitor vismodegib: a single center experience.

J Eur Acad Dermatol Venereol 2019 Feb 5. Epub 2019 Feb 5.

Department of Dermatology, University of Naples Federico II, Naples, Italy.

We read with great interest the article entitled "Managing adverse effects by dose reduction during routine treatment of locally advanced basal cell carcinoma (laBCC) with the hedgehog inhibitor vismodegib: a single center experience" recently published in your journal and we want to report also our experience regarding the effect of dose reduction of hedgehog inhibitor vismodegib treatment as a new therapeutic option in order to reduce the high frequency of adverse events and increase patients compliance. This article is protected by copyright. All rights reserved. Read More

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http://dx.doi.org/10.1111/jdv.15469DOI Listing
February 2019

Peritumoral clefting as a key feature in differentiating basal cell carcinoma from trichoblastoma through in-vivo reflectance confocal microscopy.

J Eur Acad Dermatol Venereol 2019 Feb 5. Epub 2019 Feb 5.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Italy.

Adnexal tumors represent one of the most troublesome differential diagnosis when dealing with skin lesions with clinical and dermoscopic criteria suggestive for basal cell carcinoma (BCC). Among these, benign follicular tumors, and in particular trichoblastoma and trichoepithelioma, deserve a special mention as BCC mimickers. These are benign tumors showing differentiation toward the outer follicular sheath. Read More

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http://dx.doi.org/10.1111/jdv.15467DOI Listing
February 2019
10 Reads

CD103 negative memory T cells may play important roles in making regulatory T cell-enriched environments in skin tumors.

J Eur Acad Dermatol Venereol 2019 Feb 5. Epub 2019 Feb 5.

Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Human skin contains resident memory T cells (T ) and central memory T cells (T ) . T are characterized by CD69 expression and can be divided into 2 subpopulations: CD103 T and CD103 T . Although both T and T showed antitumor efficacy in a mouse model , little is known about their role in human skin cancer. Read More

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http://dx.doi.org/10.1111/jdv.15478DOI Listing
February 2019

Basal Cell Carcinoma Pathology Requests and Reports Are Lacking Important Information.

J Skin Cancer 2019 3;2019:4876309. Epub 2019 Jan 3.

Department of Dermatology, Jordan University of Science and Technology, P.O. Box 3030, Irbid, Jordan.

Introduction: Basal cell carcinoma (BCC) is the most common cancer affecting humans. Luckily it has negligible risk for metastasis; however it can be locally destructive to surrounding tissue. The diagnosis of this tumor relies on clinical and dermoscopic features; however confirmation requires biopsy and histologic examination. Read More

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http://dx.doi.org/10.1155/2019/4876309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335659PMC
January 2019
1 Read

Koebner phenomenon: pemphigus vulgaris following Mohs micrographic surgery.

Dermatol Online J 2019 Jan 15;25(1). Epub 2019 Jan 15.

The Thomas Jefferson University, Department of Dermatology, Philadelphia, Pennsylvania.

Koebnerization of pemphigus vulgaris (PV) is an infrequently reported reaction. We present a 65-year-old man with Koebnerized pemphigus vulgaris after Mohs microscopic surgery for a basal cell carcinoma. We present this case to heighten awareness of the phenomenon in the dermatological community. Read More

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January 2019
6 Reads

Tissue-sparing properties of Mohs micrographic surgery for infiltrative basal cell carcinoma.

J Am Acad Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands; Department of Dermatology, Roosevelt Clinic, Leiden, the Netherlands. Electronic address:

Background: Mohs micrographic surgery (MMS) should lead to tissue sparing of healthy skin compared to standard surgical excision, because smaller surgical margins are used.

Objective: To quantify the tissue-sparing properties of MMS in primary basal cell carcinoma (BCC) with an infiltrative growth pattern.

Methods: A prospective study including 256 primary BCC with an infiltrative growth pattern was performed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622193016
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http://dx.doi.org/10.1016/j.jaad.2019.01.057DOI Listing
January 2019
7 Reads

Understanding roofers' sun protection behaviour: A qualitative study.

J Eur Acad Dermatol Venereol 2019 Feb 1. Epub 2019 Feb 1.

Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.

The incidence of keratinocyte carcinoma (KC), which includes squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and actinic keratosis (AK), has steadily increased in the last few decades; moreover, KC is the most common malignancy in Caucasians worldwide. As exposure to solar ultraviolet radiation (UVR) is the main risk factor for KC, outdoor workers bear a high risk for KC. Therefore, SCC and AK were officially recognised as occupational diseases in Germany in 2015. Read More

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http://dx.doi.org/10.1111/jdv.15460DOI Listing
February 2019
1 Read

Loss of primary cilia drives switching from Hedgehog to Ras/MAPK pathway in resistant basal cell carcinoma.

J Invest Dermatol 2019 Jan 29. Epub 2019 Jan 29.

Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford CA, United States of America. Electronic address:

Basal cell carcinomas (BCCs) rely on Hedgehog (HH) pathway growth signal amplification by the microtubule-based organelle, the primary cilium. Despite naïve tumors responsiveness to Smoothened inhibitors (Smo), resistance in advanced tumors remains frequent. While the resistant BCCs usually maintain HH pathway activation, squamous cell carcinomas with Ras/MAPK pathway activation also arise, with the molecular basis of tumor type and pathway selection still obscure. Read More

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http://dx.doi.org/10.1016/j.jid.2018.11.035DOI Listing
January 2019

What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 2: Epidemiology, aetiology and risk factors.

Clin Exp Dermatol 2019 Jan 31. Epub 2019 Jan 31.

Centre of Evidence Based Dermatology, University of Nottingham, King's Meadow Campus, Lenton Lane, Nottingham, UK.

This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It presents the key findings from 14 systematic reviews published in 2016, focusing on AE epidemiology, aetiology and risk factors. For systematic reviews on the treatment and prevention of AE and for nomenclature and outcome assessments, see Parts 1 and 3 of this update, respectively. Read More

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http://dx.doi.org/10.1111/ced.13853DOI Listing
January 2019
1 Read

Risk Factors for Keratinocyte Carcinoma Skin Cancer In Nonwhite Individuals: A Retrospective Analysis.

J Am Acad Dermatol 2019 Jan 28. Epub 2019 Jan 28.

Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA. Electronic address:

Background: As the majority of the U.S. population will consist of nonwhite individuals by the year 2043, it is essential that both physicians and patients are educated about skin cancer in nonwhite individuals. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.01.038DOI Listing
January 2019
1 Read

Facial site distribution of basal cell carcinoma in Japanese.

Exp Dermatol 2019 Feb;28 Suppl 1:69-71

Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Basal cell carcinoma (BCC) occurs preferentially on the face. We retrospectively analyzed 200 cases of BCC treated at Nagoya City University Hospital from April 2004 to October 2015 and examined regional features based on modified facial aesthetic units. BCC occurred more frequently on the cheek, nasal and orbital areas. Read More

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http://dx.doi.org/10.1111/exd.13829DOI Listing
February 2019

Metaplastic basal cell carcinoma developing into syringomatous carcinoma: An enigmatic case report.

J Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Department of Dermatology, Kansai Medical University Medical Center, Osaka, Japan.

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http://dx.doi.org/10.1111/1346-8138.14793DOI Listing
January 2019
1 Read

A systematic review on the use of cryotherapy versus other treatments for basal cell carcinoma.

Dermatol Online J 2018 Nov 15;24(11). Epub 2018 Nov 15.

Department of Dermatology, University of California Davis, Sacramento, CA.

Background: Cryotherapy is a commonly discussed method for treatment of basal cell carcinoma skin cancer. Some uncertainty remains about its efficacy relative to other modalities.

Objective: To determine the efficacy and adverse events profile of cryotherapy for the treatment of basal cell carcinoma compared to other therapeutic options or non-intervention. Read More

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November 2018

Sonic Hedgehog Pathway Inhibitors: from Clinical Trials to Clinical Practice.

Br J Dermatol 2019 Jan 28. Epub 2019 Jan 28.

Memorial Sloan Kettering Cancer Center, Dermatology Service 16 E. 60th Street, 4th Floor Dermatology, New York, NY, 10022.

Basal cell carcinoma (BCC) is the most common malignancy. It can rarely become locally advanced (laBCC) or metastasize (mBCC). For recurrent, inoperable, laBCC and/or mBCC, Sonic Hedgehog (Shh) pathway inhibitors, vismodegib and sonidegib, are treatment options. Read More

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http://doi.wiley.com/10.1111/bjd.17692
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http://dx.doi.org/10.1111/bjd.17692DOI Listing
January 2019
1 Read

Mast Cells Are a Marked Source for Complement C3 Products That Associate with Increased CD11b-Positive Cells in Keratinocyte Skin Carcinomas.

Cancer Invest 2019 Jan 28:1-12. Epub 2019 Jan 28.

a Department of Dermatology , Kuopio University Hospital, University of Eastern Finland , Kuopio , Finland.

By using immunohistochemistry and antibodies that identify complement C3c (in C3 and C3b) or CD11b receptor, we report that the proportion C3c mast cells and the number of CD11b cells are increased in basal cell carcinoma (BCC). Instead, only CD11b cells are increased in squamous cell carcinoma/Bowen's disease, and only slightly so in actinic keratosis. Only C3c mast cells are increased in psoriasis. Read More

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http://dx.doi.org/10.1080/07357907.2019.1565765DOI Listing
January 2019
1 Read

Commentary on BRCA1-Associated Protein-1 Tumor Predisposition Syndrome in a Patient With Numerous Basal Cell Carcinomas.

Authors:
Joshua Arbesman

Dermatol Surg 2019 Feb;45(2):319-320

Department of Dermatology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

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http://dx.doi.org/10.1097/DSS.0000000000001627DOI Listing
February 2019

A trichogenic tumor with aggressive features initially diagnosed as basal cell carcinoma.

Dermatol Online J 2018 Sep 15;24(9). Epub 2018 Sep 15.

Department of Dermatology, University School of Medicine, Durham, North Carolina.

Trichoblastic carcinoma is a rare carcinoma often arising in a pre-existing trichoblastoma. It may resemble basal cell carcinoma, posing a diagnostic challenge. Trichoblastic carcinoma is divided into low-grade and high-grade tumors. Read More

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September 2018

Basal cell carcinoma with intravascular invasion: A case report and review of the literature.

Dermatol Online J 2018 Oct 15;24(10). Epub 2018 Oct 15.

Carilion Clinic Dermatology and Mohs Surgery, Roanoke, Virginia.

The significance of basal cell carcinoma (BCC) invading the intravascular space is unknown. We report a case of an infiltrative BCC on the scalp that showed evidence of both intravascular and perineural invasion. The tumor locally recurred in the bone marrow space 4. Read More

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October 2018

Dermatology on YouTube - an update and analysis of new trends.

Dermatol Online J 2018 Dec 15;24(12). Epub 2018 Dec 15.

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado Dermatology Service, US Department of Veteran Affairs, Eastern Colorado Health Care System, Denver, Colorado.

Because YouTube is one of the most popular search engines, it is an instrumental tool to stay up to date on the most relevant dermatology trends and content in order to better direct patients and improve health outcomes. Twelve select terms (i.e. Read More

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December 2018
6 Reads

SOX2 knockdown inhibits the migration and invasion of basal cell carcinoma cells by targeting the SRPK1-mediated PI3K/AKT signaling pathway.

Oncol Lett 2019 Feb 7;17(2):1617-1625. Epub 2018 Dec 7.

Department of Dermatology, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China.

Basal cell carcinoma (BCC) is the most common type of human skin cancer, which is driven by the aberrant activation of Hedgehog signaling. Previous evidence indicated that sex determining region Y-box 2 (SOX2) is associated with the tumor metastasis. However, the expression and role of SOX2 in BCC remain unknown. Read More

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http://dx.doi.org/10.3892/ol.2018.9810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341784PMC
February 2019
0.987 Impact Factor

Cell phone usefulness to improve the skin cancer screening: preliminary results and critical analysis of mobile app development.

Rural Remote Health 2019 Jan 24;19(1):4895. Epub 2019 Jan 24.

Barretos Cancer Hospital, Street Antenor Duarte Villela, 1331 - Dr. Paulo Prata, Barretos - SP, 14784-400, Brazil

Introduction: The high incidence of skin cancer in Brazil has resulted in an urgent need for more efficient methods of reducing the time between initial diagnosis and therapy. Such delays are significant in large countries like Brazil, where a considerable proportion of the population live in remote areas with limited access to specialized medical care. To address this problem the use of mobile phones as screening devices for suspicious skin lesions has been incorporated as long-distance teledermatology services. Read More

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https://www.rrh.org.au/journal/article/4895
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http://dx.doi.org/10.22605/RRH4895DOI Listing
January 2019
4 Reads

Comment on "Diagnostic accuracy of ex vivo fluorescence confocal microscopy for Mohs surgery of basal cell carcinomas: A prospective study on 753 margins".

Br J Dermatol 2019 Jan 23. Epub 2019 Jan 23.

Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.

We read with interest the paper by Longo C. et al. regarding the diagnostic accuracy of ex vivo fluorescence confocal microscopy (FCM) for Mohs surgery (MMS) of basal cell carcinomas and we appreciated the potential of this imaging tool. Read More

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http://dx.doi.org/10.1111/bjd.17686DOI Listing
January 2019
1 Read

Diagnostic impact of reflectance confocal microscopy as a second-level examination for facial skin lesions.

J Dtsch Dermatol Ges 2019 Jan 22. Epub 2019 Jan 22.

Department of Dermatology, Medical University of Graz, Graz, Austria.

Background And Objective: Benign and malignant facial skin lesions may be difficult to differentiate clinically and with dermoscopy. The present study aimed to evaluate the potential utility of in vivo reflectance confocal microscopy (RCM) as a second-level examination for facial skin neoplasms.

Patients And Methods: Retrospective and blinded evaluation of 160 consecutive facial lesions was carried out in two separate steps. Read More

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http://doi.wiley.com/10.1111/ddg.13748
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http://dx.doi.org/10.1111/ddg.13748DOI Listing
January 2019
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Trends in the treatment and prevention of keratinocyte carcinoma (non-melanoma skin cancer).

Authors:
Alexander Zink

Curr Opin Pharmacol 2019 Jan 17;46:19-23. Epub 2019 Jan 17.

Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany; Clinical Unit Allergology, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Neuherberg, Germany. Electronic address:

Keratinocyte carcinoma (KC), previously also known as non-melanoma skin cancer, is the most common malignancy worldwide. It comprises basal cell carcinoma, squamous cell carcinoma (SCC), and actinic keratoses as carcinoma in situ or precursors of SCC. With solar ultraviolet radiation being the main risk factor, several countries have accepted KC as an occupational disease of outdoor professions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14714892183009
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http://dx.doi.org/10.1016/j.coph.2018.12.002DOI Listing
January 2019
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Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

Oncol Lett 2019 Jan 8;17(1):927-932. Epub 2018 Nov 8.

Department of Pathology, Dongying People's Hospital, Dongying, Shandong 257091, P.R. China.

The expression levels of seven types of cytokeratin (CK) in different kinds of skin adnexal tumors were evaluated. One hundred and thirty-two patients with different kinds of skin adnexal tumors admitted and treated in the Department of Dermatology of Dongying People's Hospital from May 2013 to May 2015 were selected and underwent tissue section staining. Another 20 cases of normal skin were enrolled as the control group. Read More

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http://dx.doi.org/10.3892/ol.2018.9679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312935PMC
January 2019
1 Read

How to Improve Compliance With Dermatologic Screening in Liver Transplant Recipients: Experience in a (Spoke) Peripheral Center for Follow-up.

Transplant Proc 2019 Jan - Feb;51(1):184-186. Epub 2018 Jun 30.

Unit for Liver Transplant Management (SATTE), AORN Sant'Anna e San Sebastiano, Caserta, Italy.

Annual dermatologic examination is required in all transplant recipients because of the high risk of skin cancers. Nevertheless, if the transplant recipient is merely advised to have a dermatologic consultation, the adherence usually appears to be poor. We analyzed our population of liver transplant recipients in 2 periods: in 2014 (group 1) and in 2016 (group 2), when we had organized the presence of a dermatologist at scheduled intervals to annually examine the entire liver transplant population we actively follow-up. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.02.215DOI Listing
June 2018
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Complete response is reversible upon vismodegib withdrawal and re-inducible upon vismodegib re-administration in a patient with locally advanced BCC.

J Eur Acad Dermatol Venereol 2019 Jan 17. Epub 2019 Jan 17.

Dermato-Oncology Unit, 1st Department of Dermatology, University of Athens, Andreas Sygros Hospital, Athens, Greece.

Recurrence after the discontinuation of Hedgehog pathway inhibitor (HPI) treatment in responding patients with advanced basal cell carcinoma (BCC) is an emerging clinical challenge. A 54-year old female patient presented in 2016 with an histologically proven BCC on the right peri-auricular area, extending to the ear, that was present for 6 years (Figure 1, upper panel). Due to considerable deformity expected with surgery, the patient was treated with vismodegib 150 mg/day. Read More

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http://dx.doi.org/10.1111/jdv.15428DOI Listing
January 2019

Skin Cancer Associated Genodermatoses: A Literature Review.

Acta Derm Venereol 2019 01 17. Epub 2019 Jan 17.

Department of Dermatology and Allergy Centre, Odense University Hospital, DK-5000 Odense, Denmark.

Skin cancer has become the most common type of cancer worldwide as a result of environmental exposure and medical treatments. A small group of patients are genetically predisposed to skin cancer and this article is intended as a diagnostic tool when encountering patients with multiple skin cancer lesions. The disorders are described with clinical characteristics, genetics and management. Read More

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http://dx.doi.org/10.2340/00015555-3123DOI Listing
January 2019
7 Reads