4,209 results match your criteria Bartonellosis


Human Bartonellosis: An Underappreciated Public Health Problem?

Trop Med Infect Dis 2019 Apr 19;4(2). Epub 2019 Apr 19.

Division of Immunology, Tulane National Primate Research Center, Tulane University Health Sciences, Covington, LA 70433, USA.

spp. bacteria can be found around the globe and are the causative agents of multiple human diseases. The most well-known infection is called cat-scratch disease, which causes mild lymphadenopathy and fever. Read More

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http://dx.doi.org/10.3390/tropicalmed4020069DOI Listing

Bartonella diversity and zoonotic potential in indigenous Tete Veld rats (Aethomys ineptus) from South Africa.

Infect Genet Evol 2019 Apr 17;73:44-48. Epub 2019 Apr 17.

Mammal Research Institute (MRI), Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Hatfield 0028, South Africa. Electronic address:

Bartonellosis is a vector-borne disease that is often misdiagnosed due to a broad range of clinical symptoms, compounded by a lack of awareness regarding the prevalence, diversity and public health impacts of regional strains. Despite recent PCR-based confirmation of Bartonella in 9.7% of non-malarial, acute febrile patients in South Africa, data regarding reservoirs of infection are limited. Read More

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http://dx.doi.org/10.1016/j.meegid.2019.04.012DOI Listing

Genetic diversity and hematological and biochemical alterations in Alouatta primates naturally infected with hemoplasmas in Brazil.

Comp Immunol Microbiol Infect Dis 2019 Apr 23;63:104-111. Epub 2019 Jan 23.

Department of Veterinary Clinical Pathology, Centro Universitário Moura Lacerda, Ribeirão Preto, SP, Brazil.

Mycoplasma spp. and Bartonella spp. are Gram-negative bacteria transmitted by arthropod vectors that infect red blood cells of several mammal species. Read More

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http://dx.doi.org/10.1016/j.cimid.2019.01.011DOI Listing

A review on the occurrence of companion vector-borne diseases in pet animals in Latin America.

Parasit Vectors 2019 Mar 28;12(1):145. Epub 2019 Mar 28.

Institute of Parasitology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.

Companion vector-borne diseases (CVBDs) are an important threat for pet life, but may also have an impact on human health, due to their often zoonotic character. The importance and awareness of CVBDs continuously increased during the last years. However, information on their occurrence is often limited in several parts of the world, which are often especially affected. Read More

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http://dx.doi.org/10.1186/s13071-019-3407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438007PMC
March 2019
1 Read

Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome.

J Cent Nerv Syst Dis 2019 18;11:1179573519832014. Epub 2019 Mar 18.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.

Background: With the advent of more sensitive culture and molecular diagnostic testing modalities, spp. infections have been documented in blood and/or cerebrospinal fluid specimens from patients with diverse neurological symptoms. Pediatric acute-onset neuropsychiatric syndrome (PANS) is characterized by an unusually abrupt onset of cognitive, behavioral, or neurological symptoms. Read More

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http://journals.sagepub.com/doi/10.1177/1179573519832014
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http://dx.doi.org/10.1177/1179573519832014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423671PMC
March 2019
11 Reads

Carrion's disease: more than a neglected disease.

Parasit Vectors 2019 Mar 26;12(1):141. Epub 2019 Mar 26.

University Hospital, Goethe-University, Institute for Medical Microbiology and Infection Control, Frankfurt am Main, Germany.

Infections with Bartonella bacilliformis result in Carrion's disease in humans. In the first phase of infection, the pathogen causes a hemolytic fever ("Oroya fever") with case-fatality rates as high as ~90% in untreated patients, followed by a chronical phase resulting in angiogenic skin lesions ("verruga peruana"). Bartonella bacilliformis is endemic to South American Andean valleys and is transmitted via sand flies (Lutzomyia spp. Read More

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http://dx.doi.org/10.1186/s13071-019-3390-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434794PMC

Isolated conjunctival granuloma as a first manifestation of Parinaud's oculoglandular syndrome: A case report.

Am J Ophthalmol Case Rep 2019 Jun 23;14:58-60. Epub 2019 Feb 23.

Centro de la Visión Filial Clínica las Condes, Santiago, Chile.

Purpose: Parinaud's oculo-glandular syndrome (POGS) is the most frequent manifestation of ocular bartonellosis, and usually presents with local lymphadenopathies and systemic symptoms. We present a case of isolated conjunctival granuloma as the sole manifestation of ocular bartonellosis.

Observations: A 67-year-old female presented to the authors' eye clinic with complaints of a 2-week history of unilateral red eye and chemosis. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402948PMC
June 2019
1 Read

Metagenomic Approach to Characterizing Disease Epidemiology in a Disease-Endemic Environment in Northern Thailand.

Front Microbiol 2019 26;10:319. Epub 2019 Feb 26.

Department of Entomology, US Army Medical Directorate of the Armed Forces Research Institute of Medical Sciences (USAMD-AFRIMS), Bangkok, Thailand.

In this study, we used a metagenomic approach to analyze bacterial communities from diverse populations (humans, animals, and vectors) to investigate the role of these microorganisms as causative agents of disease in human and animal populations. Wild rodents and ectoparasites were collected from 2014 to 2018 in Nan province, Thailand where scrub typhus is highly endemic. Samples from undifferentiated febrile illness (UFI) patients were obtained from a local hospital. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399164PMC
February 2019
2 Reads

Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1.

Int J Gen Med 2019 18;12:101-119. Epub 2019 Feb 18.

Hudson Valley Healing Arts Center, Hyde Park, NY 12538, USA,

Purpose: We collected data from an online survey of 200 of our patients, which evaluated the efficacy of dapsone (diaminodiphenyl sulfone, ie, DDS) combined with other antibiotics and agents that disrupt biofilms for the treatment of chronic Lyme disease/post-treatment Lyme disease syndrome (PTLDS). We also collected aggregate data from direct retrospective chart review, including laboratory testing for Lyme, other infections, and associated tick-borne coinfections. This helped us to determine the frequency of exposure to other infections/coinfections among a cohort of chronically ill Lyme patients, evaluate the efficacy of newer "persister" drug regimens like DDS, and determine how other infections and tick-borne coinfections may be contributing to the burden of chronic illness leading to resistant symptomatology. Read More

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http://dx.doi.org/10.2147/IJGM.S193608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388746PMC
February 2019
2 Reads

Bartonella henselae- and quintana-associated uveitis: a case series and approach of a potentially severe disease with a broad spectrum of ocular manifestations.

Int Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.

Purpose: To evaluate the clinical manifestations of intraocular inflammation associated with Bartonella infection and describe the assessment and management of patients with cat-scratch disease (CSD).

Methods: This is a retrospective review of the clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2011 to 2018 in the Department of Ocular Inflammations and Infections of the University Eye Clinic of Ioannina (Greece). An analysis of the current literature concerning Bartonella-related intraocular infections was also carried out. Read More

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http://link.springer.com/10.1007/s10792-019-01096-7
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http://dx.doi.org/10.1007/s10792-019-01096-7DOI Listing
March 2019
18 Reads

Multimodality imaging of multifocal ocular bartonellosis with an optic nerve head mass.

Can J Ophthalmol 2019 Feb 19;54(1):e3-e6. Epub 2018 Jun 19.

James Paget University Hospital, Great Yarmouth, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00084182173131
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http://dx.doi.org/10.1016/j.jcjo.2018.02.019DOI Listing
February 2019
10 Reads

Bartonella henselae and Bartonella clarridgeiae infection, hematological changes and associated factors in domestic cats and dogs from an Atlantic rain forest area, Brazil.

Acta Trop 2019 May 27;193:163-168. Epub 2019 Feb 27.

Universidade Federal Fluminense, Faculdade de Veterinária, Departamento de Patologia e Clínica Veterinária, Rua Vital Brasil Filho, 64 - Santa Rosa, Niterói - RJ, 24230-340; Rio de Janeiro, Brazil. Electronic address:

Cats are considered main reservoir of Bartonella henselae, which is transmitted to other cats especially through Ctenocephalides felis fleas, and to humans through scratching and biting. Serra da Tiririca State Park (PESET) is an Atlantic Forest area that shelters a wide variety of endemic fauna. Recently, the park has been suffering due to irregular housing construction and domestic animal population that interacts with humans and wildlife. Read More

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http://dx.doi.org/10.1016/j.actatropica.2019.02.026DOI Listing
May 2019
1 Read

Seroprevalence of six pathogens transmitted by the Ixodes ricinus ticks in asymptomatic individuals with HIV infection and in blood donors.

Sci Rep 2019 Feb 14;9(1):2117. Epub 2019 Feb 14.

Department of Parasitology, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096, Warsaw, Poland.

The objective of our study was to estimate the seroprevalence of six pathogens transmitted by ticks in HIV-infected persons and blood donors in Poland (B. burgdorferi s.l. Read More

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http://dx.doi.org/10.1038/s41598-019-38755-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376038PMC
February 2019
3 Reads

Human Tick-Borne Diseases in Australia.

Front Cell Infect Microbiol 2019 28;9. Epub 2019 Jan 28.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

There are 17 human-biting ticks known in Australia. The bites of , and can cause paralysis, inflammation, and severe local and systemic reactions in humans, respectively. Six ticks, including , and may transmit , or subsp. Read More

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http://dx.doi.org/10.3389/fcimb.2019.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360175PMC
January 2019
7 Reads

False Negative Results in Bartonellosis Diagnosis.

Vector Borne Zoonotic Dis 2019 Feb 7. Epub 2019 Feb 7.

1 Department of Medicine, University of Campinas (UNICAMP), Campinas, Brazil.

We report a fatal case of Bartonella henselae bacteremic patient. He had negative serology and PCRs from whole blood and liquid culture; only ftsZ nested PCR was positive from the blood liquid culture. The isolate had positive PCRs. Read More

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https://www.liebertpub.com/doi/10.1089/vbz.2018.2378
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http://dx.doi.org/10.1089/vbz.2018.2378DOI Listing
February 2019
3 Reads
2.298 Impact Factor

Feline bartonellosis key issues and possible vectors

Ann Parasitol 2018;64(4):309-315

Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences, ul. Głęboka 30, 20-612 Lublin, Poland

Bartonellosis is a disease caused by Bartonella spp. microorganisms which belong to the Rickettsiales order. This disease is a zoonosis, B. Read More

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April 2019
3 Reads

Effectiveness of a 10% imidacloprid/4.5% flumethrin polymer matrix collar in reducing the risk of Bartonella spp. infection in privately owned cats.

Parasit Vectors 2019 Feb 1;12(1):69. Epub 2019 Feb 1.

Dipartimento di Medicina Veterinaria, Università degli Studi di Bari "Aldo Moro", Bari, Italy.

Background: Bartonella henselae, Bartonella clarridgeiae and the rare Bartonella koehlerae are zoonotic pathogens, with cats being regarded as the main reservoir hosts. The spread of the infection among cats occurs mainly via fleas and specific preventive measures need to be implemented. The effectiveness of a 10% imidacloprid/4. Read More

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http://dx.doi.org/10.1186/s13071-018-3257-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359753PMC
February 2019
5 Reads

Anti-NMDAR Encephalitis in Association with Herpes Simplex Virus and Viral and Bacterial Zoonoses.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):102-103

Department of Neurology, Kuala Lumpur Hospital, Jalan Pahang, 50586 Kuala Lumpur, Malaysia.

Multiple co-infections can predispose a patient to autoimmune encephalitis. Out of thirty cases of N-methyl-D-aspartate receptor (NMDAR) encephalitis seen at a single tertiary referral center, only two cases of co-infection with NMDAR encephalitis were identified. One of these cases was highly interesting due to the presence of more than one co-infections along with the presence of cortical dysfunction, seizures, and orofacial dyskinesias at the onset in a male in the absence of tumors, which was refractory to initial treatment. Read More

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http://www.annalsofian.org/text.asp?2019/22/1/102/248504
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http://dx.doi.org/10.4103/aian.AIAN_232_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327714PMC
January 2019
3 Reads

Comparative Ecology of and Infections in Wild Carnivores.

Front Vet Sci 2018 4;5:322. Epub 2019 Jan 4.

Centers for Disease Control and Prevention, Fort Collins, CO, United States.

Phylogenetic sister clades and within the order Rhizobiales present some common biological characteristics as well as evident differences in adaptations to their mammalian reservoirs. We reviewed published data on and infections in wild carnivores to compare the ecology of these bacteria in relatively similar host environments. Arthropod vectors are the main mechanism for species transmission between mammalian hosts. Read More

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http://dx.doi.org/10.3389/fvets.2018.00322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328487PMC
January 2019
3 Reads

Interaction of bacteria and stem cells in health and disease.

FEMS Microbiol Rev 2019 03;43(2):162-180

Institut für Medizinische Mikrobiologie und Krankenhaushygiene, University Hospital, Goethe University, Paul-Ehrlich-Str. 40, D-60596 Frankfurt am Main, Germany.

Adult stem and progenitor cells possess unique qualities of proliferative capacity and phenotypic plasticity making their potential interactions with pathogenic and commensal bacteria a significant factor in health and disease. This interaction may result in the hindrance of regenerative capacity and degenerative disease. In other contexts, bacterial-stem cell cross-talk plays an important role in regulating stem cell renewal and maintaining homeostasis. Read More

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https://academic.oup.com/femsre/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/femsre/fuz003DOI Listing
March 2019
8 Reads

Molecular Mechanisms of and Mammalian Erythrocyte Interactions: A Review.

Front Cell Infect Microbiol 2018 12;8:431. Epub 2018 Dec 12.

UMR BIPAR, INRA, ANSES, École Nationale Vétérinaire d'Alfort, Université Paris-Est Créteil Val-de-Marne, Maisons-Alfort, France.

Bartonellosis is an infectious disease caused by species that are distributed worldwide with animal and public health impact varying according to species, infection phase, immunological characteristics, and geographical region. is widely present in various mammals including cats, rodents, ruminants, and humans. At least 13 species or subspecies are zoonotic. Read More

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00431
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http://dx.doi.org/10.3389/fcimb.2018.00431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299047PMC
December 2018
9 Reads

Microbiome Analysis Reveals the Presence of spp. and spp. in Deer Keds ().

Front Microbiol 2018 20;9:3100. Epub 2018 Dec 20.

Institute for Medical Microbiology and Infection Control, University Hospital, Goethe-University, Frankfurt am Main, Germany.

The deer ked () is distributed in Europe, North America, and Siberia and mainly infests cervids as roe deer, fallow deer, and moose. From a one health perspective, deer keds occasionally bite other animals or humans and are a potential vector for . This bacterium belongs to a lineage of ruminant-associated spp. Read More

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http://dx.doi.org/10.3389/fmicb.2018.03100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306446PMC
December 2018
1 Read

Combination of microbiome analysis and serodiagnostics to assess the risk of pathogen transmission by ticks to humans and animals in central Germany.

Parasit Vectors 2019 Jan 7;12(1):11. Epub 2019 Jan 7.

University Hospital, Goethe-University, Institute for Medical Microbiology and Infection Control, Frankfurt am Main, Germany.

Background: Arthropod-borne diseases remain a major health-threat for humans and animals worldwide. To estimate the distribution of pathogenic agents and especially Bartonella spp., we conducted tick microbiome analysis and determination of the infection status of wild animals, pets and pet owners in the state of Hesse, Germany. Read More

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http://dx.doi.org/10.1186/s13071-018-3240-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322329PMC
January 2019
1 Read

Bartonella spp. Bloodstream Infection in a Canadian Family.

Vector Borne Zoonotic Dis 2019 Apr 27;19(4):234-241. Epub 2018 Dec 27.

1 Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Historically, Bartonella spp. have been associated with febrile illness (Oroya fever, trench fever, and cat scratch disease), endocarditis (numerous Bartonella spp.), and vasoproliferative lesions (Bartonella bacilliformis, Bartonella quintana, Bartonella henselae, and Bartonella vinsonii subsp. Read More

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http://dx.doi.org/10.1089/vbz.2018.2353DOI Listing
April 2019
3 Reads

Disseminated Bartonella henselae disease mimicking Langerhans' cell histiocytosis.

Pediatr Blood Cancer 2019 Apr 17;66(4):e27573. Epub 2018 Dec 17.

Infectious Disease Research Program, Center for Bone Marrow Transplantation, Department of Pediatric Hematology and Oncology, Children's University Hospital Münster, Münster, Germany.

Bartonella henselae, the causative agent of cat-scratch disease, has been recognized to be responsible for a broad range of clinical syndromes. We report the case of a patient with disseminated B. henselae infection mimicking Langerhans cell histiocytosis at presentation and its successful management with neurosurgery, prolonged antibacterial therapy, and observation. Read More

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http://dx.doi.org/10.1002/pbc.27573DOI Listing
April 2019
3 Reads
2.562 Impact Factor

Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA.

Ticks Tick Borne Dis 2019 02 27;10(2):360-364. Epub 2018 Nov 27.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University (NCSU), 1060 William Moore Drive, Raleigh, NC 27607, USA. Electronic address:

The objective of this work was to determine the prevalence of Borrelia and Bartonella species in Ixodes spp. ticks collected from 16 USA states. Genus PCR amplification and sequence analysis of Bartonella and Borrelia 16SsRNA-23SsRNA intergenic regions were performed on DNA extracted from 929 questing adult ticks (671 Ixodes scapularis, 155 Ixodes affinis, and 103 Ixodes pacificus). Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.11.015DOI Listing
February 2019
1 Read

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry as a useful tool for the rapid identification of wild flea vectors preserved in alcohol.

Med Vet Entomol 2018 Dec 5. Epub 2018 Dec 5.

Institut de Recherche pour le Développement (IRD), Assistance Publique-Hôpitaux de Marseille (AP-HM), Service de Santé des Armées (SSA), Vecteurs-Infections Tropicales et Méditerranéennes (VITROME), Institut Hospitalo-Universitaire (IHU) Méditerranée Infection, Aix Marseille University, Marseille, France.

Flea identification is a significant issue because some species are considered as important vectors of several human pathogens that have emerged or re-emerged recently, such as Bartonella henselae (Rhizobiales: Bartonellaceae) and Rickettsia felis (Rickettsiales: Rickettsiaceae). Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been evaluated in recent years for the identification of multicellular organisms, including arthropods. A preliminary study corroborated the usefulness of this technique for the rapid identification of fleas, creating a preliminary database containing the spectra of five species of flea. Read More

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http://dx.doi.org/10.1111/mve.12351DOI Listing
December 2018
3 Reads

Bartonella infections in cats and dogs including zoonotic aspects.

Parasit Vectors 2018 Dec 4;11(1):624. Epub 2018 Dec 4.

Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.

Bartonellosis is a vector-borne zoonotic disease with worldwide distribution that can infect humans and a large number of mammals including small companion animals (cats and dogs). In recent years, an increasing number of studies from around the world have reported Bartonella infections, although publications have predominantly focused on the North American perspective. Currently, clinico-pathological data from Europe are more limited, suggesting that bartonellosis may be an infrequent or underdiagnosed infectious disease in cats and dogs. Read More

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http://dx.doi.org/10.1186/s13071-018-3152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280416PMC
December 2018
4 Reads

Molecular detection and clinical characteristics of Bartonella bacilliformis, Leptospira spp., and Rickettsia spp. in the Southeastern Peruvian Amazon basin.

BMC Infect Dis 2018 Dec 4;18(1):618. Epub 2018 Dec 4.

School of Medicine. Faculty of Health Sciences. Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.

Background: Acute febrile illness (AFI) represent a significant health challenge in the Peruvian Amazon basin population due to their diverse etiologies and the unavailability of specific on-site diagnostic methods, resulting in underreporting of cases. In Peru, one of the most endemic regions to dengue and leptospirosis is Madre de Dios, a region also endemic to emergent bacterial etiologic agents of AFI, such as bartonellosis and rickettsiosis, whose prevalence is usually underreported. We aimed to molecularly identify the presence of Leptospira spp. Read More

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http://dx.doi.org/10.1186/s12879-018-3541-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280516PMC
December 2018
4 Reads

Human Exposure to Novel Bartonella Species from Contact with Fruit Bats.

Emerg Infect Dis 2018 12;24(12):2317-2323

Twice a year in southwestern Nigeria, during a traditional bat festival, community participants enter designated caves to capture bats, which are then consumed for food or traded. We investigated the presence of Bartonella species in Egyptian fruit bats (Rousettus aegyptiacus) and bat flies (Eucampsipoda africana) from these caves and assessed whether Bartonella infections had occurred in persons from the surrounding communities. Our results indicate that these bats and flies harbor Bartonella strains, which multilocus sequence typing indicated probably represent a novel Bartonella species, proposed as Bartonella rousetti. Read More

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http://dx.doi.org/10.3201/eid2412.181204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256376PMC
December 2018
40 Reads

Effectiveness of antibiotic therapy in pediatric patients with cat scratch disease.

Int J Clin Pharm 2018 Dec 16;40(6):1458-1461. Epub 2018 Nov 16.

College of Pharmacy, The Ohio State University, 500 W. 12th Ave, Columbus, OH, 43210, USA.

Background Appropriate antibiotic treatment of cat scratch disease (CSD) in pediatrics is not well established. Objective The purpose of this study was to evaluate the response rates of antibiotic therapy in pediatrics with CSD. Methods The electronic medical records of a cohort of pediatric patients with confirmed diagnosis of CSD (2006-2016) were reviewed, retrospectively. Read More

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http://dx.doi.org/10.1007/s11096-018-0746-1DOI Listing
December 2018
18 Reads

Global fingerprint of humans on the distribution of Bartonella bacteria in mammals.

PLoS Negl Trop Dis 2018 11 15;12(11):e0006865. Epub 2018 Nov 15.

Department of Biology, Stanford University, Stanford, California, United States of America.

As humans move and alter habitats, they change the disease risk for themselves, their commensal animals and wildlife. Bartonella bacteria are prevalent in mammals and cause numerous human infections. Understanding how this genus has evolved and switched hosts in the past can reveal how current patterns were established and identify potential mechanisms for future cross-species transmission. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006865
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http://dx.doi.org/10.1371/journal.pntd.0006865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237287PMC
November 2018
14 Reads

Survey and Phylogenetic Analysis of Rodents and Important Rodent-Borne Zoonotic Pathogens in Gedu, Bhutan.

Korean J Parasitol 2018 Oct 31;56(5):521-525. Epub 2018 Oct 31.

International Development Group, School of Veterinary Science, Massey University, Palmerston North, New Zealand.

Rodents are well-known reservoirs and vectors of many emerging and re-emerging infectious diseases, but little is known about their role in zoonotic disease transmission in Bhutan. In this study, a cross-sectional investigation of zoonotic disease pathogens in rodents was performed in Chukha district, Bhutan, where a high incidence of scrub typhus and cases of acute undifferentiated febrile illness had been reported in people during the preceding 4-6 months. Twelve rodents were trapped alive using wire-mesh traps. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
Publisher Site
http://dx.doi.org/10.3347/kjp.2018.56.5.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243181PMC
October 2018
21 Reads

Testing for Bartonella ssp. DNA in cerebrospinal fluid of dogs with inflammatory central nervous system disease.

J Vet Intern Med 2018 Nov 31;32(6):1983-1988. Epub 2018 Oct 31.

From the Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.

Background: Neurobartonellosis occurs in people. The role these organisms might play in inflammatory brain disease of dogs is unclear.

Hypothesis/objectives: That Bartonella spp. Read More

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http://doi.wiley.com/10.1111/jvim.15288
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http://dx.doi.org/10.1111/jvim.15288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271302PMC
November 2018
1 Read

Parinaud's Oculoglandular Syndrome in Cat Scratch Disease.

N Engl J Med 2018 Nov;379(18):e31

Universidad de Antioquia, Medellín, Colombia

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http://dx.doi.org/10.1056/NEJMicm1804942DOI Listing
November 2018
5 Reads

Plant-feeding phlebotomine sand flies, vectors of leishmaniasis, prefer .

Proc Natl Acad Sci U S A 2018 11 29;115(46):11790-11795. Epub 2018 Oct 29.

Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, The Kuvin Centre for the Study of Infectious and Tropical Diseases, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel;

Blood-sucking phlebotomine sand flies (Diptera: Psychodidae) transmit leishmaniasis as well as arboviral diseases and bartonellosis. Sand fly females become infected with parasites and transmit them while imbibing vertebrates' blood, required as a source of protein for maturation of eggs. In addition, both females and males consume plant-derived sugar meals as a source of energy. Read More

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http://dx.doi.org/10.1073/pnas.1810435115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243281PMC
November 2018
17 Reads

Neurological presentations of Bartonella henselae infection.

Neurol Sci 2019 Feb 27;40(2):261-268. Epub 2018 Oct 27.

Neurology Department, Complejo Hospitalario Universitario Pontevedra, Loureiro Crespo, 2, 36002, Pontevedra, Spain.

Objective: Neurological symptoms in patients with cat-scratch disease (CSD) have been rarely reported. The aim of this study is to analyze the frequency of neurological CSD (NCSD) and describe the disease clinical presentation, management and outcome.

Material And Methods: We retrospectively selected patients with a CSD syndrome and Bartonella IgG titers > 1:256. Read More

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http://link.springer.com/10.1007/s10072-018-3618-5
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http://dx.doi.org/10.1007/s10072-018-3618-5DOI Listing
February 2019
12 Reads

Untangling the knots: Co-infection and diversity of Bartonella from wild gerbils and their associated fleas.

Mol Ecol 2018 Dec 4;27(23):4787-4807. Epub 2018 Dec 4.

Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Based on molecular data, previous studies have suggested a high overall diversity and co-infection rates of Bartonella bacteria in wild rodents and their fleas. However, partial genetic characterization of uncultured co-infecting bacteria limited sound conclusions concerning intra- and inter-specific diversity of the circulating Bartonella. To overcome this limitation, Bartonella infections of wild populations of two sympatric gerbil species and their fleas were explored by multiple isolations of Bartonella organisms. Read More

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http://dx.doi.org/10.1111/mec.14906DOI Listing
December 2018
18 Reads

Bartonella quintana, past, present, and future of the scourge of World War I.

Authors:
Joaquim Ruiz

APMIS 2018 Nov;126(11):831-837

Independent Researcher, Barcelona, Spain.

During World War I, a mysterious new disease affected soldiers on both sides of battle field. The first reports described a relapsing fever of unknown origin with body lice being suggested as the vector. The outbreak affected >1 000 000 people, mostly soldiers fighting in front-line trenches. Read More

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http://doi.wiley.com/10.1111/apm.12895
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http://dx.doi.org/10.1111/apm.12895DOI Listing
November 2018
22 Reads

Current Status of Tick-Borne Diseases in South Korea.

Vector Borne Zoonotic Dis 2019 Apr 17;19(4):225-233. Epub 2018 Oct 17.

1 Department of Internal Medicine and Inha University School of Medicine, Incheon, Republic of Korea.

Background: Bites with tick-borne pathogens can cause various bacterial, viral, or parasitic diseases in humans. Tick-transmitted diseases are known as contributing factors to the increasing incidence and burden of diseases. The present article investigated the epidemiology of tick-borne diseases in South Korea. Read More

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http://dx.doi.org/10.1089/vbz.2018.2298DOI Listing
April 2019
10 Reads

Bartonella henselae in a dog with ear tip vasculitis.

Vet Dermatol 2018 Dec 14;29(6):537-e180. Epub 2018 Oct 14.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, 1050 William Moore Drive, Raleigh, NC, 27607, USA.

Background: Bartonella henselae, a Gram-negative, zoonotic, alpha-proteobacteria has been previously implicated in association with cutaneous vasoproliferative lesions (bacillary angiomatosis), nodular panniculitis and multifocal erythema (erythema multiforme) in dogs.

Objective: Describe clinical, microbiological and histological lesions in a dog with ear margin vasculitis and B. henselae infection. Read More

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http://dx.doi.org/10.1111/vde.12695DOI Listing
December 2018
4 Reads

ESCCAR international congress on Rickettsiae and other intracellular bacteria.

Microbes Infect 2018 Aug - Sep;20(7-8):392-400. Epub 2018 Oct 10.

Institute of Microbiology, University of Lausanne and University Hospital, Faculty of Biology and Medicine, Lausanne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S12864579183014
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http://dx.doi.org/10.1016/j.micinf.2018.08.001DOI Listing
March 2019
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Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs.

J Vet Intern Med 2018 Nov 11;32(6):1958-1964. Epub 2018 Oct 11.

Department of Clinical Sciences and the Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Because of poor sensitivity and questionable specificity of immunofluorescent antibody assays (IFAs), serological diagnosis of Bartonella species infections in dogs remains challenging. Despite limitations, IFA testing is the historical "gold standard" for Bartonella serodiagnosis in animals and humans. Because most diagnostic laboratories test against only 1 or 2 Bartonella spp. Read More

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http://dx.doi.org/10.1111/jvim.15301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271329PMC
November 2018
3 Reads

Identification of Leptospira and Bartonella among rodents collected across a habitat disturbance gradient along the Inter-Oceanic Highway in the southern Amazon Basin of Peru.

PLoS One 2018 9;13(10):e0205068. Epub 2018 Oct 9.

U.S. Naval Medical Research Unit No. 6, Callao, Peru.

Background: The southern Amazon Basin in the Madre de Dios region of Peru has undergone rapid deforestation and habitat disruption, leading to an unknown zoonotic risk to the growing communities in the area.

Methodology/principal Findings: We surveyed the prevalence of rodent-borne Leptospira and Bartonella, as well as potential environmental sources of human exposure to Leptospira, in 4 communities along the Inter-Oceanic Highway in Madre de Dios. During the rainy and dry seasons of 2014-2015, we captured a total of 97 rodents representing 8 genera in areas that had experienced different degrees of habitat disturbance. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205068PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177132PMC
March 2019
8 Reads

Bartonella henselae Infection in Sickle Cell Disease Mice Is Associated with Hyperalgesia.

Vector Borne Zoonotic Dis 2019 Feb 29;19(2):102-105. Epub 2018 Sep 29.

4 Laboratory Applied Research in Dermatology and Bartonella Infection, Division of Dermatology, Department of Medicine, University of Campinas (UNICAMP) , Campinas, Sao Paulo, Brazil .

Background: Sickle cell disease (SCD) is the most prevalent hematologic genetic disorder. Acute vaso-occlusive painful crisis is the hallmark of the disease and may be related to subclinical infections. Bartonellosis, a rare and neglected infection, is caused by Bartonella spp. Read More

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http://dx.doi.org/10.1089/vbz.2018.2331DOI Listing
February 2019
3 Reads
2.300 Impact Factor

Genetic diversity, infection prevalence, and possible transmission routes of Bartonella spp. in vampire bats.

PLoS Negl Trop Dis 2018 09 27;12(9):e0006786. Epub 2018 Sep 27.

Odum School of Ecology, University of Georgia, Athens, Georgia, United States of America.

Bartonella spp. are globally distributed bacteria that cause endocarditis in humans and domestic animals. Recent work has suggested bats as zoonotic reservoirs of some human Bartonella infections; however, the ecological and spatiotemporal patterns of infection in bats remain largely unknown. Read More

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https://dx.plos.org/10.1371/journal.pntd.0006786
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http://dx.doi.org/10.1371/journal.pntd.0006786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159870PMC
September 2018
17 Reads

Development of a Specific and Sensitive Enzyme-Linked Immunosorbent Assay as an Diagnostic Tool for Detection of Bartonella henselae Antibodies in Human Serum.

J Clin Microbiol 2018 Dec 27;56(12). Epub 2018 Nov 27.

University Hospital, Goethe-University, Institute for Medical Microbiology and Infection Control, Frankfurt am Main, Germany

causes cat scratch disease and several other clinical entities. Infections with are frequently occurring; however, the infection is only rarely diagnosed, mainly due to a lack of knowledge in the medical community. Microscopic immunofluorescence assays (IFA) are widely used for the serodiagnosis of infections but are laborious and time-consuming, and interpretation is subjective. Read More

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http://dx.doi.org/10.1128/JCM.01329-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258866PMC
December 2018
6 Reads

Bartonella quintana and Bartonella vinsonii subsp. vinsonii bloodstream co-infection in a girl from North Carolina, USA.

Med Microbiol Immunol 2019 Feb 24;208(1):101-107. Epub 2018 Sep 24.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Dr., Raleigh, NC, 27607, USA.

The genus Bartonella consists of globally distributed and highly diverse alpha-proteobacteria that infect a wide-range of mammals. Medically, Bartonella spp. constitute emerging, vector-borne, zoonotic, intravascular organisms that induce long-lasting bacteremia in reservoir-adapted (passive carrier of a microorganism) hosts. Read More

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http://link.springer.com/10.1007/s00430-018-0563-0
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http://dx.doi.org/10.1007/s00430-018-0563-0DOI Listing
February 2019
7 Reads

Zoonotic pathogens in fluctuating common vole (Microtus arvalis) populations: occurrence and dynamics.

Parasitology 2019 Mar 24;146(3):389-398. Epub 2018 Sep 24.

Instituto de Investigación en Recursos Cinegéticos,IREC (CSIC-UCLM-JCCM), Ronda de Toledo s/n, 13071, Ciudad Real,Spain.

Diseases and host dynamics are linked, but their associations may vary in strength, be time-lagged, and depend on environmental influences. Where a vector is involved in disease transmission, its dynamics are an additional influence, and we often lack a general understanding on how diseases, hosts and vectors interact. We report on the occurrence of six zoonotic arthropod-borne pathogens (Anaplasma, Bartonella, Borrelia, Coxiella, Francisella and Rickettsia) in common voles (Microtus arvalis) throughout a population fluctuation and how their prevalence varies according to host density, seasonality and vector prevalence. Read More

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http://dx.doi.org/10.1017/S0031182018001543DOI Listing
March 2019
4 Reads

Infections with Bartonella spp. in free-ranging cervids and deer keds (Lipoptena cervi) in Norway.

Comp Immunol Microbiol Infect Dis 2018 Jun 29;58:26-30. Epub 2018 Jun 29.

Vytautas Magnus University, Vileikos str. 8, LT-44404 Kaunas, Lithuania. Electronic address:

Bartonella bacteria are arthropod-borne and can cause long-term bacteremia in humans and animals. The predominant arthropod vectors and the mode of transmission for many novel Bartonella species remain elusive or essentially unstudied. The aim of this study was to investigate the prevalence of Bartonella spp. Read More

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http://dx.doi.org/10.1016/j.cimid.2018.06.003DOI Listing
June 2018
1 Read