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Nutr Hosp 2022 Jun 23. Epub 2022 Jun 23.

Instituto de Investigación Sanitaria La Paz (IdiPAZ). Hospital Universitario La Paz.

Obesity is a public health problem due to its high prevalence, high morbidity, and high mortality. The relationship between eating disorders (ED) and obesity is widely established. A healthcare professional that cares for people with obesity must take into account a series of best practices to minimize the risk of developing an ED in the course of treatment for weight loss. Read More

Nutr Diet 2022 Jun 23. Epub 2022 Jun 23.

Upper Gastrointestinal Surgery, St George Private Hospital, Sydney, New South Wales, Australia.

Aims: Bariatric surgery remains an effective treatment for the condition of obesity. However it predisposes patients to nutritional deficiencies and related complications. The aim of this study was to identify nutritional abnormalities, weight loss, adherence to supplements, and presence of gastrointestinal symptoms in a cohort of bariatric surgical patients. Read More

Nutrients 2022 Jun 14;14(12). Epub 2022 Jun 14.

Optometry and Vision Sciences Research Group, Aston University, Birmingham B4 7ET, UK.

The aim of the present research was to assess the effect of bariatric surgery-induced weight loss on the tear film and ocular surface of patients with obesity. A total of 29 participants with obesity (aged 47.2 ± 10. Read More

Nutrients 2022 Jun 8;14(12). Epub 2022 Jun 8.

Department of Research, Innlandet Hospital Trust, P.O. Box 104, N-2381 Brumunddal, Norway.

The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the two most commonly used procedures: gastric bypass (RYGB) and sleeve gastrectomy (SG). Adult patients with morbid obesity were assigned to receive either RYGB or SG. Read More

J Clin Med 2022 Jun 20;11(12). Epub 2022 Jun 20.

Department of Metabolic Diseases, Faculty of Medicine, Jagiellonian University Medical College, 30-688 Krakow, Poland.

The World Health Organization (WHO) has identified obesity and overweight as an epidemic of the 21st century [... Read More

J Clin Med 2022 Jun 14;11(12). Epub 2022 Jun 14.

Surgical Directorate, General University Hospital of Patras, 265 04 Rio, Greece.

We read with great interest the article by Zawadzka et al. [.. Read More

J Clin Med 2022 Jun 10;11(12). Epub 2022 Jun 10.

Department of Digestive, Oncologic and Bariatric Surgery, Hôpital Européen Georges Pompidou, AP-HP, F-75015 Paris, France.

Obesity is a global scourge, affecting over 15% of the world's population [... Read More

Int J Mol Sci 2022 Jun 20;23(12). Epub 2022 Jun 20.

Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.

Breast cancer-associated fibroblasts (BCAFs), the most abundant non-cancer stromal cells of the breast tumor microenvironment (TME), dramatically sustain breast cancer (BC) progression by interacting with BC cells. BCAFs, as well as myofibroblasts, display an up regulation of activation and inflammation markers represented by α-smooth muscle actin (α-SMA) and cyclooxygenase 2 (COX-2). BCAF aggregates have been identified in the peripheral blood of metastatic BC patients. Read More

Int J Environ Res Public Health 2022 Jun 9;19(12). Epub 2022 Jun 9.

Faculty of Psychology, Universidad Nacional de Educación a Distancia (UNED), 28040 Madrid, Spain.

Background: Bariatric surgery is the most effective method for achieving accelerated weight loss. However, in the short- and medium-term, between 20% and 40% of patients regain a significant percentage of the weight lost. Cognitive and attitudinal psychological variables contribute to explaining weight regain. Read More

Int J Environ Res Public Health 2022 Jun 9;19(12). Epub 2022 Jun 9.

Postgraduate Program in Neuroscience and Behavior, Federal University of Pará, Belém 66075-110, PA, Brazil.

Purpose: To analyze the correlation between anxiety symptoms and perceived quality of life in women more than 24 months after undergoing bariatric surgery.

Methods: Cross-sectional, descriptive and analytical study, carried out with women who underwent bariatric surgery after at least 24 months. To assess the level of anxiety symptoms, the Beck Inventory was used and to assess the perception of quality of life, the Item Short Form Healthy Survey was applied. Read More

Biomedicines 2022 May 31;10(6). Epub 2022 May 31.

Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA.

More than 30% of people in the United States (US) are classified as obese, and over 50% are considered significantly overweight. Importantly, obesity is a risk factor not only for the development of metabolic syndrome but also for many cancers, including pancreatic ductal adenocarcinoma (PDAC). PDAC is the third leading cause of cancer-related death, and 5-year survival of PDAC remains around 9% in the U. Read More

Microbiome 2022 Jun 24;10(1):96. Epub 2022 Jun 24.

Department of Internal Medicine I, Division of Endocrinology, Diabetes and Metabolism, University Medical Center Bonn, Bonn, Germany.

Background: Bariatric surgery remains the most effective therapy for adiposity reduction and remission of type 2 diabetes. Although different bariatric procedures associate with pronounced shifts in the gut microbiota, their functional role in the regulation of energetic and metabolic benefits achieved with the surgery are not clear.

Methods: To evaluate the causal as well as the inherent therapeutic character of the surgery-altered gut microbiome in improved energy and metabolic control in diet-induced obesity, an antibiotic cocktail was used to eliminate the gut microbiota in diet-induced obese rats after gastric bypass surgery, and gastric bypass-shaped gut microbiota was transplanted into obese littermates. Read More

J Transl Med 2022 Jun 23;20(1):283. Epub 2022 Jun 23.

School of Nutrition and Centre Nutrition, Santé et Société (NUTRISS)-Institut sur la nutrition et les aliments fonctionnels (INAF), Université Laval, Pavillon des Services (suite 2729K), 2440 Hochelaga Blvd, Quebec City, QC, G1V 0A6, Canada.

Background: Bariatric surgery is an effective therapy for individuals with severe obesity to achieve sustainable weight loss and to reduce comorbidities. Examining the molecular signature of subcutaneous adipose tissue (SAT) following different types of bariatric surgery may help in gaining further insight into their distinct metabolic impact.

Results: Subjects undergoing biliopancreatic diversion with duodenal switch (BPD-DS) showed a significantly higher percentage of total weight loss than those undergoing gastric bypass or sleeve gastrectomy (RYGB + SG) (41. Read More

Obes Surg 2022 Jun 23. Epub 2022 Jun 23.

Department of General Surgery, Bariatric Surgery Program, Hospital Privado Universitario de Córdoba, Av. Naciones Unidas 346, Córdoba Capital, Argentina.

Purpose: Obesity has an especial implication for women of childbearing age because of a higher risk of adverse outcomes during pregnancy and labor. This report aimed to analyze complications of pregnancy after sleeve gastrectomy (SG) concerning the time after surgery.

Methods: A retrospective descriptive-analytical study was conducted including women of childbearing age who underwent sleeve gastrectomy (SG) from 2006 to 2017. Read More

Obes Surg 2022 Jun 23. Epub 2022 Jun 23.

Department of Gastrointestinal and Pediatric Surgery, and Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, 4950 0424, Oslo, PB, Norway.

Purpose: After bariatric surgery, body contouring surgery (BCS) is thought to improve body image, weight loss, and mental health. Many patients desire but do not undergo BCS after bariatric surgery. This patient subset has rarely been studied. Read More

Obes Surg 2022 Jun 23. Epub 2022 Jun 23.

Biomedical Signals and Systems, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, 7522 NB, Enschede, The Netherlands.

Purpose: This study aims to (1) quantify physical behavior through self-reports and sensor-based measures, (2) examine the correlation between self-reported and sensor-based physical activity (PA) and (3) assess whether bariatric patients adhere to PA guidelines.

Methods: A Fitbit accelerometer was used to collect minute-to-minute step count and heart rate data for 14 consecutive days. Total physical activity levels (PAL), moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior (SB) were used to quantify physical behavior. Read More

Sci Rep 2022 Jun 23;12(1):10643. Epub 2022 Jun 23.

Department of Medical, Surgical and Neurological Sciences, UOC Endocrinology, University of Siena, Siena, Italy.

A single nucleotide polymorphism in the Type 2 deiodinase (DIO2) gene (p.Thr92Ala) was found to be associated with hypertension, type 2 diabetes mellitus (T2DM), insulin resistance, and body mass index (BMI). We retrospectively evaluated 182 patients to assess whether the DIO2 p. Read More

Surg Obes Relat Dis 2022 May 18. Epub 2022 May 18.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Curr Obes Rep 2022 Jun 23. Epub 2022 Jun 23.

Division of Pediatric Surgery, Children's National Hospital, 111 Michigan Ave. NW, Washington, DC, 20010, USA.

Purpose Of Review: Approximately 20% of children and adolescents in the USA suffer from obesity with significant long-term effects well into adulthood. Metabolic and bariatric surgery, although well adopted in the adult population, has been underutilized in children.

Recent Findings: There are four categories of weight loss devices regulated by the Food and Drug Administration for use in adults - gastric bands, gastric balloon systems, electrical stimulation systems, and gastric emptying systems. Read More

Surg Endosc 2022 Jun 23. Epub 2022 Jun 23.

Department of Surgery, Brigham and Woman's Hospital, c/o Surgery Education Office, 75 Francis Street, Boston, MA, 02120, USA.

Background: Recent data describing gastrointestinal (GI) symptoms experienced by patients after bariatric surgery is lacking, and previous studies in sleeve gastrectomy patients have been limited in scope of follow-up time or extent of GI symptoms examined. We sought to characterize the prevalence and time course of patient-reported eating-related symptoms in sleeve gastrectomy patients.

Methods: From July 2020 to July 2021, sleeve gastrectomy patients seen at three Boston area hospitals received electronic surveys and prospectively reported GI symptoms using the BODY-Q eating-related symptoms scale. Read More

Ann Med Surg (Lond) 2022 Jun 16;78:103787. Epub 2022 May 16.

Department of General Surgery, University Hospital Brandenburg an der Havel, Hochstraße 29, 14770, Brandenburg an der Havel, Germany.

Background: In bariatric surgery the laparoscopic Roux-en-Y gastric bypass (LRYGB) has been proven to be a safe and effective approach. Currently the optimal size of the linear-stapled gastrojejunostomy (GJ) and its impact on weight loss are not known due to a lack of clinical trials on that topic. We aimed to provide evidence on the impact of the GJ size in terms of gastric bypass weight loss. Read More

Ann Med Surg (Lond) 2022 Jun 20;78:103799. Epub 2022 May 20.

Department of Surgery, Rawalpindi Medical University, Block E Satellite Town, Rawalpindi, Pakistan.

Front Med (Lausanne) 2022 6;9:894465. Epub 2022 Jun 6.

Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Purpose: Obesity is associated with fat accumulation in ectopic sites such as the pancreas, the so-called pancreatic steatosis (PS). Bariatric surgery has been shown to be associated with reducing pancreatic fat. This study investigated the effect of laparoscopic sleeve gastrectomy (LSG) on pancreatic volume and its fat content and glucose homeostasis. Read More

Trials 2022 Jun 22;23(1):526. Epub 2022 Jun 22.

Center for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.

Background: The one anastomosis gastric bypass (OAGB) is being performed by an increasing number of bariatric centers over the world. However, the optimal length of the biliopancreatic (BP) limb remains a topic of discussion. Retrospective studies suggest the benefit of tailoring BP-limb length; however, randomized trials are lacking. Read More

Sci Rep 2022 Jun 22;12(1):10507. Epub 2022 Jun 22.

Department of Surgery, Minimally Invasive Surgery Research Center, Division of Minimally Invasive and Bariatric Surgery, Rasool-e Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

In patients with BMI ≥ 50 kg/m, it is difficult to select an appropriate procedure that can lead to optimum results. This study aims to evaluate mid-term weight loss outcomes in patients with BMI ≥ 50 kg/m following one anastomosis gastric bypass (OAGB) as a one-stage procedure. A prospective study was conducted on patients with BMI ≥ 50 kg/m, aged 18 years and above who had undergone primary OAGB from January 2016 to February 2019 with at least two years follow-ups. Read More

Int J Surg 2022 Jun 19;104:106716. Epub 2022 Jun 19.

Bariatric Surgery Service, Hospital Essalud Alberto Sabogal Sologuren, Lima, Peru.

Background: Nowadays, the high morbimortality of obesity is mainly related to diabetes, cancer, and hypertension. It is reported that obesity in patients with hypertension can lead to resistance to pressure reduction through pharmacological therapy and lifestyle changes, so bariatric surgery emerges as a proposed treatment for obesity.

Methods: We performed an umbrella review that included systematic reviews of clinical trials that evaluated patients with hypertension and non-morbid obesity. Read More

Sci Transl Med 2022 Jun 22;14(650):eabo4474. Epub 2022 Jun 22.

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Prediction of hepatocellular carcinoma (HCC) risk is an urgent unmet need in patients with nonalcoholic fatty liver disease (NAFLD). In cohorts of 409 patients with NAFLD from multiple global regions, we defined and validated hepatic transcriptome and serum secretome signatures predictive of long-term HCC risk in patients with NAFLD. A 133-gene signature, prognostic liver signature (PLS)-NAFLD, predicted incident HCC over up to 15 years of longitudinal observation. Read More

Obes Surg 2022 Jun 22. Epub 2022 Jun 22.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Oregon Health & Science University, Portland, OR, USA.

Purpose: Sex differences exist in the associations between obesity and the risk of colorectal cancer (CRC). However, limited data exist on how sex affects CRC risk after bariatric surgery.

Materials And Methods: This retrospective cohort study used the 2012-2020 MarketScan database. Read More

Surg Endosc 2022 Jun 22. Epub 2022 Jun 22.

Roy J. and Lucille A. Carver College of Medicine, MIS, Bariatric and GI Surgery, 200 Hawkins Drive 4634 JCP, Iowa City, IA, 52242-1086, USA.

Background: The COVID-19 epidemic imposed significant stressors on individuals and changed how medical care is delivered. The affect that this stress has placed on the field of bariatric surgery and the associated outcomes is not well established.

Methods: A retrospective review of a prospectively collected database from a single academic institution was conducted. Read More

J Laparoendosc Adv Surg Tech A 2022 Jun 22. Epub 2022 Jun 22.

Nutrition Department, Cardiology Institute, University Foundation of Cardiology, Porto Alegre, Brazil.

Staple line oversewing (SLO) is a prophylactic alternative due to its low cost and its effect of decreasing the incidence and severity of bleeding complications in sleeve gastrectomy (SG). However, this approach significantly increases the surgical time and may be associated with stenosis. The study aims to identify whether its usage was sufficient to optimize the surgical time in patients whose screening for the risk of occult bleeding was negative. Read More