241 results match your criteria Balanitis Xerotica Obliterans


Abnormal dartos fascia in buried penis and hypospadias: Evidence from histopathology.

J Pediatr Urol 2018 Dec 21;14(6):536.e1-536.e7. Epub 2018 Jun 21.

Department of Urology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta Pusat, Indonesia.

Introduction: The importance of the pathology of the dartos fascia in hypospadias and buried penis is still debatable. Understanding the properties of connective tissue of dartos fascia in hypospadias and buried penis may give a clue to the underlying mechanism.

Objective: This study aimed to compare connective tissue and vascularization of dartos fascia between normal penis, buried penis, and hypospadias. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14775131183031
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http://dx.doi.org/10.1016/j.jpurol.2018.04.034DOI Listing
December 2018
14 Reads

Surgical management of genitourinary lichen sclerosus et atrophicus in boys in England: A 10-year review of practices and outcomes.

J Pediatr Urol 2019 Feb 29;15(1):45.e1-45.e5. Epub 2018 Mar 29.

Alder Hey Children's Hospital, Liverpool, UK. Electronic address:

Introduction: Circumcision has long been the mainstay of management for genitourinary lichen sclerosus et atrophicus (LS); however, there has been growing interest in surgical techniques that preserve the foreskin.

Objective: The aim of this study was to assess population-based surgical management of LS in England and determine surgical outcomes.

Study Design: Cases of LS treated in English NHS trusts (2002-2011) were extracted from the Hospital Episode Statistics (HES) Database. Read More

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http://dx.doi.org/10.1016/j.jpurol.2018.02.027DOI Listing
February 2019
3 Reads

Surgical management of buried penis in adults.

Cent European J Urol 2018 22;71(3):346-352. Epub 2018 Sep 22.

Luton and Dunstable Hospital, Department of Urology, Luton, United Kingdom.

Introduction: Buried penis is a condition that causes the penis to become hidden beneath the skin. It has a significant impact on quality of life and can present in a variety of ways, with lower urinary tract symptoms and erectile dysfunction being common. Whilst there are several causes, obesity is the most common in adults. Read More

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http://ceju.online/journal/2018/obesity-surgical-interventio
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http://dx.doi.org/10.5173/ceju.2018.1676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202613PMC
September 2018
9 Reads

Balanitis xerotica obliterans: a review of diagnosis and management.

Int J Dermatol 2018 Oct 12. Epub 2018 Oct 12.

Department of Dermatology, Royal North Shore Hospital, Sydney, Australia.

Balanitis xerotica obliterans (BXO), or penile lichen sclerosus, is a progressive sclerosing inflammatory dermatosis of the glans penis and foreskin. It is associated with significant morbidity and may result in impaired urinary and sexual function. It was initially described by Stuhmer in 1928, named after its pathological features, and is considered the male equivalent of vulvar lichen sclerosis (LS). Read More

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http://doi.wiley.com/10.1111/ijd.14236
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http://dx.doi.org/10.1111/ijd.14236DOI Listing
October 2018
5 Reads

Can lichen sclerosus be diagnosed by preputial appearance or symptoms?

Res Rep Urol 2018 18;10:89-94. Epub 2018 Sep 18.

Department of Pediatric Urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Japan,

Introduction: Lichen sclerosus (LS), or balanitis xerotica obliterans, is a chronic, inflammatory disease accompanied by cicatrizing skin conditions resulting in pathologic phimosis. LS can be detected clinically by the whitish appearance of the glans or the foreskin, thickened, nonretractable foreskin, dysuria, and spraying. However, diagnosis is confirmed histopathologically. Read More

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https://www.dovepress.com/can-lichen-sclerosus-be-diagnosed-
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http://dx.doi.org/10.2147/RRU.S173184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149835PMC
September 2018
25 Reads

Circumcision in the paediatric patient: A review of indications, technique and complications.

J Paediatr Child Health 2018 Dec 23;54(12):1299-1307. Epub 2018 Sep 23.

Department of Paediatric Surgery and Urology, Monash Children's Hospital, Melbourne, Victoria, Australia.

Circumcision is one of the most commonly performed surgical procedures in the world. Despite this, the practice of paediatric circumcision remains highly controversial, and continues to generate ongoing debate. This debate has become more relevant recently with the provisional guidelines from the Centers for Disease Control and Prevention recommending a change of practice. Read More

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http://doi.wiley.com/10.1111/jpc.14206
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http://dx.doi.org/10.1111/jpc.14206DOI Listing
December 2018
20 Reads

Evaluation and management of adult acquired buried penis.

Transl Androl Urol 2018 Aug;7(4):618-627

Department of Urology, University of California Irvine, Irvine, California, USA.

Adult acquired buried penis represents the clinical manifestation of a wide spectrum of pathology due to a variety of etiologies. It can be related to obesity, a laxity in connective tissue, lichen sclerosis (LS), complications from penile/scrotal enlargement surgery, scrotal lymphedema, or hidradenitis suppurativa (HS). Buried penis can be associated with poor cosmesis and hygiene, voiding dysfunction, and sexual dysfunction. Read More

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http://tau.amegroups.com/article/view/19702/20459
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http://dx.doi.org/10.21037/tau.2018.05.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127540PMC
August 2018
10 Reads

Dermoscopy of Inflammatory Genital Diseases: Practical Insights.

Dermatol Clin 2018 Oct;36(4):451-461

Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Via L. Ariosto 35, Ferrara 44121, Italy.

Diagnosis of genital inflammatory disorders may be difficult for several reasons, such as their similar appearance, possible misdiagnosis with infectious and malignant conditions, and peculiar anatomic conditions that may lead to modification of clinical features. Dermoscopy could be included as a part of the clinical inspection of genital diseases to support diagnosis, as well as to ideally avoid unnecessary invasive investigation. Practical guidance for the use of dermoscopy in the assessment of the main inflammatory genital diseases is provided, namely for lichen sclerosus, lichen planus, psoriasis, lichen simplex chronicus, and plasma cell mucositis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07338635183108
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http://dx.doi.org/10.1016/j.det.2018.05.013DOI Listing
October 2018
25 Reads

10 Years' Experience in Balanitis Xerotica Obliterans: A Single-Institution Study.

Eur J Pediatr Surg 2018 Aug 21. Epub 2018 Aug 21.

Department of Paediatric Surgery, Evelina London Children Hospital, London, United Kingdom.

Introduction:  Balanitis xerotica obliterans (BXO) is uncommon in children. Diagnosis of the condition is almost always clinical and supported by histology. Our aim was to evaluate the outcomes of children undergoing circumcision for BXO and explore the correlation between surgical and histological findings. Read More

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http://dx.doi.org/10.1055/s-0038-1668562DOI Listing
August 2018
8 Reads

Utility of uroflowmetry during the follow-up of children affected by balanitis xerotica obliterans (BXO).

Arch Ital Urol Androl 2018 Jun 30;90(2):123-126. Epub 2018 Jun 30.

Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", Unit of Paediatric Surgery, University of Messina.

Introduction: To evaluate the outcome of circumcised patients with balanitis xerotica obliterans (BXO) using uroflowmetry (UF).

Methods: Between 2011 and 2013, 180 children underwent a circumcision for phimosis. The foreskin was examined on microscopy. Read More

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http://dx.doi.org/10.4081/aiua.2018.2.123DOI Listing
June 2018
4 Reads

Lichen Sclerosus Accompanied by Urethral Squamous Cell Carcinoma: A Retrospective Study From a Urethral Referral Center.

Am J Mens Health 2018 09 21;12(5):1692-1699. Epub 2018 Jun 21.

1 Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

To evaluate the characteristics of lichen sclerosus (LS) accompanied by urethral squamous cell carcinoma (USCC) and to raise urologists' awareness about the early management of LS, a retrospective analysis was performed on the clinical features, diagnosis, treatment, and prognosis of 18 male genital LS accompanied by USCC patients who were referred to Shanghai Sixth People's Hospital between June 2000 and August 2014. All of the patients had a long-term history of LS, urethral strictures, and urethral dilatation. Seven patients are with distal (glanular or penile) USCC, 10 patients with proximal USCC, and one with entire USCC. Read More

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http://dx.doi.org/10.1177/1557988318782095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142166PMC
September 2018
25 Reads

Surgical Management of Fossa Navicularis and Distal Urethral Strictures.

Curr Urol Rep 2018 Apr 17;19(6):43. Epub 2018 Apr 17.

SUNY Upstate Medical University, Syracuse, NY, USA.

Purpose Of Review: Urethral reconstruction has evolved in the last several decades with the introduction of various techniques including fasciocutaneous skin flaps and buccal mucosal grafts. However, distal urethral strictures have continued to be a reconstructive challenge due to tendency for adverse cosmetic outcomes, risks of glans dehiscence or fistula formation, and stricture recurrence.

Recent Findings: The surgical options for treatment of distal urethral strictures have changed throughout the years; however, there is no one universally accepted technique for their treatment. Read More

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http://dx.doi.org/10.1007/s11934-018-0792-1DOI Listing
April 2018
2 Reads

Anti-Inflammatory and Tissue Regenerative Effects of Topical Treatment with Ozonated Olive Oil/Vitamin E Acetate in Balanitis Xerotica Obliterans.

Molecules 2018 Mar 13;23(3). Epub 2018 Mar 13.

Department of Human Pathology of Adult and Childhood "Gaetano Barresi", University of Messina, Via Consolare Valeria, 98123 Messina, Italy.

Balanitis xerotica obliterans (BXO) is a chronic inflammatory skin disorder, considered the male genital variant of lichen sclerosus. Anti-inflammatory drugs are commonly used in BXO. We evaluated the effects of an innovative formulation of ozonated olive oil with vitamin E acetate (OZOILE) on the inflammatory status and tissue remodeling in male children with BXO. Read More

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http://dx.doi.org/10.3390/molecules23030645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017296PMC
March 2018
16 Reads

Routine histopathological examination of the foreskin after circumcision for clinically suspected lichen sclerosus in children: Is it a waste of resources?

Can Urol Assoc J 2018 May 6;12(5):E231-E233. Epub 2018 Feb 6.

Division of Urology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.

Introduction: Circumcision is one of the most widely performed procedures in the world. One of the indications for circumcision is lichen sclerosis (LS). The natural history of LS in children is not as well-documented as in adult patients. Read More

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http://cuaj.ca/index.php/journal/article/view/4331
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http://dx.doi.org/10.5489/cuaj.4331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966935PMC
May 2018
15 Reads

Does application of topical steroids for lichen sclerosus (balanitis xerotica obliterans) affect the rate of circumcision? A systematic review.

J Pediatr Surg 2018 Nov 3;53(11):2225-2227. Epub 2018 Jan 3.

Department of Surgery, Alder Hey Children's Hospital, Liverpool, UK; University of Liverpool, Liverpool, United Kingdom. Electronic address:

Purpose: To determine whether treatment of lichen sclerosus et atrophicus (LS), with topical steroids reduces the rate of circumcision.

Methods: Two independent reviewers performed a literature search of studies reporting treatment of LS with topical steroids using EMBASE and MEDLINE database(s).

Inclusion Criteria: boys aged 0-18 years, clinical diagnosis of LS, treatment with topical steroids. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.12.021DOI Listing
November 2018
13 Reads

[Clinical and immunohistochemical correlation of balanitis xerotica obliterans].

Cir Pediatr 2017 Oct 25;30(4):211-215. Epub 2017 Oct 25.

Cirugía Pediátrica. Hospital Universitario Reina Sofía. Córdoba.

Aim: Balanitis xerotica obliterans (BXO) is a disease of the skin and mucosa of male genitals of unknown etiology that may affect children of any age. It has a low incidence (9-19%) and in adults is considered a potential premalignant lesion. The aim of our study is to establish the incidence of BXO in our center and to determine its correlation between the clinical and immunohistochemical (IHC) findings. Read More

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October 2017
3 Reads

Role of urethral plate and fossa navicularis biopsies in the detection of balanitis xerotica obliterans in boys undergoing redo hypospadias repair.

Arab J Urol 2017 Dec 15;15(4):326-330. Epub 2017 Sep 15.

Department of Urology, Faculty of Medicine, Menoufia University, Menoufia Governorate, Egypt.

Objectives: To evaluate the presence of balanitis xerotica obliterans (BXO), clinically and pathologically, in the urethra of boys with failed previous hypospadias repair and where surgical management was planned.

Patients And Methods: Between February 2010 and March 2015, boys with failed distal penile hypospadias repair who were planned for surgical management were evaluated for the presence of clinical and pathological evidence of BXO. Samples were obtained from the urethral plate and fossa navicularis, after obtaining informed consent and ethical approval. Read More

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http://dx.doi.org/10.1016/j.aju.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717454PMC
December 2017
8 Reads

The Association Between BXO and Obesity in Boys Undergoing Circumcision.

Glob Pediatr Health 2017 24;4:2333794X17742749. Epub 2017 Nov 24.

Nationwide Children's Hospital, Columbus, OH, USA.

This study investigated whether boys with balanitis xerotica obliterans (BXO) have increased rates of obesity compared with boys with no concern for BXO (NCB). Boys ≤18 years old with circumcision pathology-confirmed BXO were compared with an age-matched group who had NCB during circumcision. Boys with BXO were found to have a mean body mass index of 70. Read More

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http://dx.doi.org/10.1177/2333794X17742749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703089PMC
November 2017
6 Reads

Squamous Cell Carcinoma of the Bulbar Urethra Accompanied by Lichen Sclerosus: A Case Report.

Am J Mens Health 2018 03 28;12(2):493-497. Epub 2017 Nov 28.

1 Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Squamous cell carcinoma (SCC) of the bulbar urethra accompanied by lichen sclerosus (LS) is rarely reported. This study reports the case of a 56-year-old man with urethral squamous cell carcinoma (USCC) accompanied by a long history of genital LS. The man presented with a painful perineal mass and had a long-term history of urethral strictures and urethral dilatation. Read More

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http://dx.doi.org/10.1177/1557988317743386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818129PMC
March 2018
8 Reads

Single-stage urethroplasty with buccal mucosal inlay graft for stricture caused by balanitis xerotica obliterans in boys: Outcomes in the medium term.

J Pediatr Urol 2018 02 31;14(1):66.e1-66.e5. Epub 2017 Oct 31.

Leeds Teaching Hospitals NHS trust, Dept Paediatric Urology, Great George Street, Leeds, United Kingdom. Electronic address:

Introduction: Balanitis xerotica obliterans (BXO) is a common condition that can affect the foreskin, glans, meatus, and urethra, and rarely can also involve urethra leading to stricture. Numerous procedures have been suggested to treat urethral stricture secondary to BXO but these have had variable results.

Objective: We describe the first prospective study of a single stage buccal mucosal inlay grafting in children with urethral strictures resistant to existing remedies. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14775131173040
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http://dx.doi.org/10.1016/j.jpurol.2017.09.015DOI Listing
February 2018
17 Reads

Squamous Cell Carcinoma Penis in a Case of Urethral Stricture Due to Lichen Sclerosus Balanitis Xerotica Obliterans: A Case Report and Review of Literature.

J Clin Diagn Res 2017 Jul 1;11(7):PD17-PD18. Epub 2017 Jul 1.

Head, Department of Urology, Sri Sathya Sai Institute of Higher Medical Sciences, Prashantigram, Ananthpur, Andhra Pradesh, India.

Penile carcinoma is considered a delayed sequel of lichen sclerosus. It is important to recognize this not so uncommon complication in time as survival of patients with Squamous Cell Carcinoma (SCC) depends on early diagnosis and treatment. We describe a case of a 49-year-old male presenting with urethral stricture due to lichen sclerosus. Read More

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http://jcdr.net/article_fulltext.asp?issn=0973-709x&year
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http://dx.doi.org/10.7860/JCDR/2017/26330.10254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583896PMC
July 2017
11 Reads

Characteristics of Idiopathic Urethral Strictures: A Link to Remote Perineal Trauma?

Urology 2017 Dec 26;110:228-233. Epub 2017 Jul 26.

Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

Objective: To characterize the physical features and reconstructive outcomes of a series of idiopathic urethral strictures (IUS) in an effort to elucidate the nature of this common yet poorly understood entity.

Patients And Methods: We retrospectively reviewed our urethroplasty database to identify men undergoing initial urethral reconstruction from 2007 to 2014 at 1 of 3 hospitals (N = 514). Patients were stratified by stricture etiology, including IUS, acute trauma, iatrogenic, hypospadias, balanitis xerotica obliterans, and radiation. Read More

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http://dx.doi.org/10.1016/j.urology.2017.07.022DOI Listing
December 2017
7 Reads

The diagnosis and management of male genital lichen sclerosus: a retrospective review of 301 patients.

J Eur Acad Dermatol Venereol 2018 Jan 16;32(1):91-95. Epub 2017 Aug 16.

Department of Dermatology, University College London Hospitals, London, UK.

Introduction: Male genital lichen sclerosus (MGLSc) is an acquired, chronic, inflammatory skin disease that is associated with significant morbidity and squamous cell carcinoma of the penis (PSCC). However, some clinical, diagnostic and management controversies endure, including the relationship with penile intraepithelial neoplasia (PeIN).

Objectives: To clarify clinical presentations, diagnostic approaches, histological findings, response to treatment and the relationship with PeIN. Read More

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http://dx.doi.org/10.1111/jdv.14488DOI Listing
January 2018
1 Read

Balanitis xerotica obliterans: has its diagnostic accuracy improved with time?

JRSM Open 2017 Jun 5;8(6):2054270417692731. Epub 2017 Jun 5.

Department of Paediatric Surgery, University Hospitals Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK.

Objectives: We observed whether general practitioners are referring more appropriately for balanitis xerotica obliterans in regards to circumcision, especially at a time of clinical concern, and whether their discriminative abilities were affected by age. We also aimed to explore if balanitis xerotica obliterans was over-diagnosed by surgeons potentially leading to unnecessary circumcisions of healthy foreskins.

Design: Cross-sectional descriptive study. Read More

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http://dx.doi.org/10.1177/2054270417692731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464383PMC
June 2017
4 Reads

Response to commentary to 'Bleeding after circumcision is more likely in children with Lichen Sclerosus (Balanitis Xerotica Obliterans)'.

Authors:
Harriet Corbett

J Pediatr Urol 2017 04 9;13(2):210-211. Epub 2016 Dec 9.

Department of General Surgery, Alder Hey Children's Hospital, Eaton Road, Liverpool, L12 2AP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jpurol.2016.11.013DOI Listing
April 2017
11 Reads

Recurrence after management of meatal balanitis xerotica obliterans.

J Pediatr Urol 2017 Apr 23;13(2):204.e1-204.e6. Epub 2016 Nov 23.

PARC Urology, Frisco, TX, USA.

Introduction: We review outcomes after management of meatal balanitis xerotica obliterans (BXO). The primary outcome was recurrent meatal BXO.

Methods: A database comprising mostly hypospadias patients was queried for meatal BXO. Read More

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http://dx.doi.org/10.1016/j.jpurol.2016.10.014DOI Listing
April 2017
7 Reads

Bleeding after circumcision is more likely in children with lichen sclerosus (balanitis xerotica obliterans).

J Pediatr Urol 2017 Apr 9;13(2):208.e1-208.e4. Epub 2016 Dec 9.

Alder Hey Children's NHS Foundation Trust, Department of Paediatric Surgery, E Prescot Rd, Liverpool, L14 5AB, UK.

Introduction: Over 27,000 circumcisions were performed in England in 2012-13. The complication rate is generally perceived to be low, although published figures vary widely. Balanitis xerotica obliterans, more correctly termed Lichen Sclerosus et atrophicus (LS), is one of the commonest indications for medical circumcision. Read More

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http://dx.doi.org/10.1016/j.jpurol.2016.10.023DOI Listing
April 2017
9 Reads

Effect of Lichen Sclerosis on Success of Urethroplasty.

Urol Clin North Am 2017 Feb;44(1):77-86

Division of Urology, Department of Surgery, Duke University Medical Center, DUMC 3146, Durham, NC 27710, USA.

Lichen sclerosis (LS) is a chronic, relapsing disease with a variable presentation. In men, genitourinary LS may affect the penile foreskin, glans, meatus, and urethra. Treatment is multifaceted, ranging from pharmacotherapy to surgery. Read More

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http://dx.doi.org/10.1016/j.ucl.2016.08.004DOI Listing
February 2017
10 Reads

[Balanitis xerotica obliterans, underdiagnosed pathology of clinical relevance].

Cir Pediatr 2015 Jul 20;28(3):133-136. Epub 2015 Jul 20.

Servicio de Cirugía Pediátrica. Unidad de Urología. Hospital Universitario Son Espases. Palma de Mallorca.

Objectives: Balanitis xerotica obliterans (BXO) is a chronic inflamatory disease, a genital form of Lichen Sclerosus in males.

Material And Methods: This retrospective and descriptive analysis was carried out by rewiew of the medical records of boys who underwent circumcision from April 2013 to April 2014. The study group consisted of boys that were circumcised due it persistant phimosis at 4 years of age, urinary symptoms or painful erection. Read More

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July 2015
13 Reads

Two-stage hypospadias repair with a free graft for severe primary and revision hypospadias: A single surgeon's experience with long-term follow-up.

J Pediatr Urol 2017 Feb 29;13(1):35.e1-35.e7. Epub 2016 Sep 29.

Department of Paediatric Urology, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JN, United Kingdom.

Introduction: Repair of severe primary and revision hypospadias is a demanding procedure. Debate continues as to whether a two-stage approach or single-stage technique is superior. The two-stage procedure with a free graft involves penile straightening followed by application of a graft for the neourethral plate at stage one; with tubularization at stage two after graft maturation. Read More

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http://dx.doi.org/10.1016/j.jpurol.2016.08.014DOI Listing
February 2017
20 Reads

Clinical Features, Complications and Autoimmunity in Male Lichen Sclerosus.

Acta Derm Venereol 2017 Mar;97(3):365-369

Department of Dermatovenereology, Sahlgrenska University Hospital, Göteborg, Sweden.

Lichen sclerosus is a chronic inflammatory disease associated with substantial morbidity. Knowledge of the aetiology and progression of lichen sclerosus is therefore needed. In this cross-sectional study, 100 male patients diagnosed with lichen sclerosus were interviewed and examined. Read More

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http://dx.doi.org/10.2340/00015555-2537DOI Listing
March 2017
5 Reads

Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans.

Int J Mol Sci 2016 Sep 14;17(9). Epub 2016 Sep 14.

Department of Human Pathology of Adult and Childhood "Gaetano Barresi", University of Messina, Messina 98125, Italy.

Balanitis xerotica obliterans (BXO) is a chronic inflammatory skin disorder of unclear etiology. The etiology and the exact molecular mechanisms underlying the disease are still unknown. The human transglutaminase (TG) family consists of several proteins with catalytic activity essential for biological processes. Read More

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http://dx.doi.org/10.3390/ijms17091551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037824PMC
September 2016
13 Reads

Penile Circular Fasciocutaneous (McAninch) Flap as an Option for Complex Anterior Urethral Stricture in Case of Non-Viable Buccal Mucosal Graft.

J Clin Diagn Res 2016 Jul 1;10(7):PD09-11. Epub 2016 Jul 1.

Assistant Professor, Department of Urology, Institute of Nephro Urology , Bangalore, Karnataka, India .

The penile circular fasciocutaneous flap (FCF) is employed in the successful single stage reconstruction of long segment complex anterior urethral strictures especially when buccal mucosa is unavailable due to various reasons. A 65-year-old gentleman, chronic smoker and tobacco chewer, hypertensive on treatment, presented with obstructive lower urinary tract symptoms for 8 months. He had no prior urethral catheterization. Read More

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http://dx.doi.org/10.7860/JCDR/2016/20404.8117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020174PMC
July 2016
17 Reads

Foreskin Morbidity in Uncircumcised Males.

Pediatrics 2016 05 6;137(5). Epub 2016 Apr 6.

Department of Pediatric Surgery, Surgical Clinic C, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; and Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Objective: As a consequence of the discussion on whether the health benefits of newborn male circumcision outweigh the risks and the discrepancies in reported figures of complications, we evaluated the incidence and morbidity of foreskin surgery due to medical indications in boys from the Capital Region of Denmark in 2014.

Methods: Medical records from all boys operated on the foreskin due to medical reasons in the Capital Region in 2014 were reviewed. Patients with hypospadias, ritual circumcision, and redo-surgery because of complications to nontherapeutic circumcision were excluded. Read More

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http://pediatrics.aappublications.org/content/pediatrics/137
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http://dx.doi.org/10.1542/peds.2015-4340DOI Listing
May 2016
14 Reads

Lichen sclerosis: clinicopathological study of 60 cases from Lebanon.

Int J Dermatol 2016 Oct 27;55(10):1076-81. Epub 2016 May 27.

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Background: Lichen sclerosus (LS) is an uncommon idiopathic chronic inflammatory debilitating disease with predilection for the genital region. Our recent encounter with an LS case exhibiting perineural inflammation microscopically prompted us to assess the features of all patients diagnosed with LS at our institution.

Materials And Methods: All cases of LS diagnosed between 1990 and 2014 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1111/ijd.13336DOI Listing
October 2016
2 Reads

Diversity of patient profile, urethral stricture, and other disease manifestations in a cohort of adult men with lichen sclerosus.

Investig Clin Urol 2016 05 10;57(3):202-7. Epub 2016 May 10.

Department of Urology, University of Michigan, Ann Arbor, MI, USA.

Purpose: Lichen sclerosus (LS) in men is poorly understood. Though uncommon, it is often severe and leads to repeated surgical interventions and deterioration in quality of life. We highlight variability in disease presentation, diagnosis, and patient factors in male LS patients evaluated at a tertiary care center. Read More

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http://dx.doi.org/10.4111/icu.2016.57.3.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869564PMC
May 2016
12 Reads

Management of Vesicoureteral Reflux by Endoscopic Injection of Dextranomer/Hyaluronic Acid in Adults.

Rev Urol 2016 ;18(1):46-50

Department of Urology, University of Kentucky College of Medicine,Lexington, KY; 3Division of Urology, Veterans Affairs Medical Center, Cooper Drive Division,Lexington, KY.

A 74-year-old man presented for evaluation after discovery of a left bladder-wall tumor. He underwent transurethral resection of bladder tumor (TURBT) operation for treatment of low-grade, Ta urothelial cancer of the bladder. The patient developed recurrent disease and returned to the operating room for repeat TURBT, circumcision, and administration of intravesical mitomycin C. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859930PMC
May 2016
7 Reads

Common urological problems in children: prepuce, phimosis, and buried penis.

Authors:
I Hy Chan K Ky Wong

Hong Kong Med J 2016 Jun 6;22(3):263-9. Epub 2016 May 6.

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

Parents often bring their children to the family doctor because of urological problems. Many general practitioners have received little training in this specialty. In this review, we aimed to provide a concise and informative review of common urological problems in children. Read More

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http://dx.doi.org/10.12809/hkmj154645DOI Listing
June 2016
5 Reads

Intraurethral Steroids are a Safe and Effective Treatment for Stricture Disease in Patients with Biopsy Proven Lichen Sclerosus.

J Urol 2016 06 18;195(6):1790-6. Epub 2015 Dec 18.

School of Medicine, Duke University (BAP), Durham, North Carolina; Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Purpose: We investigated outcomes of the contemporary practice of administering intraurethral steroids to treat stricture disease in patients with biopsy proven lichen sclerosus.

Materials And Methods: We performed an institutional review board approved review of the records of patients with biopsy proven lichen sclerosus stricture disease from October 2010 to September 2015. Study inclusion criteria were age 18 years or greater and male gender. Read More

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http://dx.doi.org/10.1016/j.juro.2015.12.067DOI Listing
June 2016
20 Reads

Penile lichen sclerosus: An urologist's nightmare! - A single center experience.

Urol Ann 2015 Jul-Sep;7(3):303-8

Department of Urology, IPGMER and SSKM Hospital, Kolkata, India.

Purpose: Penile lichen sclerosus (LS) is a nagging condition and its progression result in devastating urinary and sexual problems and reduction in the quality-of-life. This study has been carried out to present our experience about this disease with simultaneous review of the available literature.

Materials And Methods: This retrospective study has been done at a tertiary care center of eastern India. Read More

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http://dx.doi.org/10.4103/0974-7796.150490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518363PMC
August 2015
5 Reads
2 Citations

Perineostomy: the last oportunity.

Int Braz J Urol 2015 Jan-Feb;41(1):91-8; discussion 99-100

Department of Urology, Reina Sofía Universitary Hospital, Córdoba, Spain.

Objective: To review the technique and outcome of perineal urethrostomy or urethral perineostomy and to identify factors related to the procedure failure.

Material And Methods: We studied 17 patients who underwent perineal urethrostomy between 2009-2013 in a single hospital. Success was defined as no need for additional surgical treatment or urethral dilatation. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752061PMC
http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.01.13DOI Listing
August 2015
53 Reads

Benign penile skin anomalies in children: a primer for pediatricians.

World J Pediatr 2015 Nov 9;11(4):316-23. Epub 2015 Mar 9.

, Padua, Italy.

Background: Abnormalities involving the skin coverage of the penis are difficult to define, but they can significantly alter penile appearance, and be a cause of parental concern.

Data Sources: The present review was based on a nonsystematic search of the English language medical literature using a combination of key words including "penile skin anomalies" and the specific names of the different conditions.

Results: Conditions were addressed in the following order, those mainly affecting the prepuce (phimosis, balanitis xerotica obliterans, balanitis, paraphimosis), those which alter penile configuration (inconspicuous penis and penile torsion), and lastly focal lesions (cysts, nevi and vascular lesions). Read More

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http://link.springer.com/content/pdf/10.1007%2Fs12519-015-00
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http://link.springer.com/10.1007/s12519-015-0015-5
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http://dx.doi.org/10.1007/s12519-015-0015-5DOI Listing
November 2015
5 Reads

Eosinophils in biopsy specimens of lichen sclerosus: a not uncommon finding.

J Cutan Pathol 2015 Jan 11;42(1):16-21. Epub 2014 Dec 11.

Department of Dermatology, University of Vermont, Burlington, VT, USA.

Background: Evolving lesions of lichen sclerosus (LS) pose a diagnostic challenge owing to an absence of classic findings of epidermal atrophy, dermal sclerosis, a band-like lymphocytic infiltrate and the presence of eosinophils.

Methods: Retrospective specimens of LS were reviewed. Demographic information, biopsy vs. Read More

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http://dx.doi.org/10.1111/cup.12445DOI Listing
January 2015
6 Reads

[Current diagnosis and treatment of male genital lichen sclerosus].

Zhonghua Nan Ke Xue 2014 Jul;20(7):579-85

Male genital lichen sclerosus (MGLSc) is a chronically relapsing disease characterized by a long course, gradual aggravation, and a tendency towards malignancy. Once called balanitis xerotica obliterans, MGLSc has a distinct predilection for the prepuce and glans, involving the urethra when aggravating, forming scarring tissues, and causing urethral stricture, which may seriously affect the patients'quality of life with such symptoms as urinary stream narrowing, dysuria, and painful penile erection. The etiology and pathogenesis of MGLSc have not yet been adequately explained though it is generally thought to be associated with autoimmune mechanism, genetic factors, infections, local trauma, and chronic urinary irritation. Read More

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July 2014
5 Reads

Meatal stenosis in boys following circumcision for lichen sclerosus (balanitis xerotica obliterans).

J Urol 2014 Dec 30;192(6):1784-8. Epub 2014 Jun 30.

Division of Child Health, University of Liverpool (PDL), Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom; Department of Surgery, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom. Electronic address:

Purpose: Of boys circumcised for penile lichen sclerosus, ie balanitis xerotica obliterans, 7% to 19% require late surgery for meatal stenosis. We review the management and outcomes of boys circumcised for lichen sclerosus.

Materials And Methods: Medical records of boys with clinical lichen sclerosus were reviewed for the period 2000 to 2010. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00225347140391
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http://dx.doi.org/10.1016/j.juro.2014.06.077DOI Listing
December 2014
22 Reads

Treatment of urethral strictures in balanitis xerotica obliterans (BXO) using circular buccal mucosal meatoplasy: experience of 15 cases.

Arch Ital Urol Androl 2014 Mar 28;86(1):23-5. Epub 2014 Mar 28.

Bakırkoy Dr. Sadi Konuk Training and Research Hospital, Department of Urology Istanbul.

Objectives: Balanitis xerotica obliterans (BXO) related strictures involving the external urethral meatus. We reviewed our result with the use of circular mucosal graft in the reconstruction of strictures.

Methods: Between March 1997 and January 2012, 15 patients underwent circular buccal mucosal urethroplasy for BXO related anterior urethral strictures. Read More

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http://dx.doi.org/10.4081/aiua.2014.1.23DOI Listing
March 2014
53 Reads

Steroid instillation for idiopathic urethritis in children: an 8-year experience.

Eur J Pediatr Surg 2015 Apr 28;25(2):212-5. Epub 2014 Mar 28.

Department of Paediatric Urology, University Hospitals Leicester, Leicester, East Midlands, United Kingdom.

Purpose: Idiopathic urethritis (IU) in children is of unknown etiology and treatment options are limited. We aim to report our experience with steroid instillation in IU in children.

Methods: Retrospective data collection of all male children diagnosed with IU over a period of 8 years. Read More

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http://dx.doi.org/10.1055/s-0034-1368800DOI Listing
April 2015
5 Reads

Isolated preputial reconstruction in distal hypospadias.

J Pediatr Urol 2014 Apr 21;10(2):399.e1-2. Epub 2013 Nov 21.

Department of Paediatric Urology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK. Electronic address:

Objective: The aim of this single centre study was to determine: a) the outcome of isolated preputial reconstruction in distal hypospadias and b) overall parental satisfaction.

Methods: A retrospective analysis of case notes was performed to determine outcome. Postal parent-satisfaction questionnaires were devised to quantify subjective assessment of care and outcome. Read More

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http://dx.doi.org/10.1016/j.jpurol.2013.10.022DOI Listing
April 2014
39 Reads