13,107 results match your criteria Bailliere\'s clinical rheumatology[Journal]


Efficacy of febuxostat versus allopurinol and the predictors of achieving target serum urate in a cohort of Thai people with gout.

Clin Rheumatol 2020 Jun 30. Epub 2020 Jun 30.

Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine, Thammasat University (Rangsit Campus), 99/209 Paholyotin Road, Khlong Luang, Pathum Thani, 12120, Thailand.

Objective: The objectives of our study were to compare the efficacy of febuxostat with allopurinol in Thai subjects with gout, as well as to determine the predictive factors of responsiveness to urate-lowering agents and to evaluate the safety of febuxostat in a real-world setting.

Methods: The study was a retrospective cohort study; a total of 354 gout patients were recruited from February 2015 to November 2018. The patients were categorized according to prescription of allopurinol or febuxostat. Read More

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http://dx.doi.org/10.1007/s10067-020-05262-6DOI Listing

Effectiveness of platelet-rich plasma in the management of hip osteoarthritis: a systematic review and meta-analysis.

Clin Rheumatol 2020 Jun 30. Epub 2020 Jun 30.

Department of Nursing and Physical Therapy, Faculty of Health Sciences, University of Alcala, Alcala, Spain.

The effectiveness of platelet-rich plasma (PRP) injections for osteoarthritis (OA) is still controversial. Previous research supports the use of intra-articular PRP injections to promote a favorable environment for joint tissue healing and to delay the progression of OA. The purpose of this review is to investigate the effectiveness of PRP in the management of hip osteoarthritis (HOA). Read More

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http://dx.doi.org/10.1007/s10067-020-05241-xDOI Listing

Anti-Cyclic Citrullinated Peptide Antibodies Correlate to Ultrasound Synovitis in Rheumatoid Arthritis Better Than C-Reactive Protein.

J Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

From the Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, National Taiwan University Hospital.

Objectives: The aim of this study was to compare ultrasound (US) grading and laboratory measures in patients with rheumatoid arthritis.

Methods: Two-hundred four patients with rheumatoid arthritis who received US evaluation for synovitis were included after excluding those using tocilizumab. Ultrasound grading of synovial hypertrophy (SH) and power Doppler (PD) at the most severe site were recorded. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001499DOI Listing

Protrusio Acetabuli.

J Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

From the Clinical Immunology and Rheumatology Unit, Department of Internal Medicine, Nehru Hospital, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1097/RHU.0000000000001468DOI Listing

Angiokeratomas-A Mimic to Remember.

J Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

From the Section of Pediatric Rheumatology, SRCC Children's Hospital, Mahalaxmi, Mumbai, India.

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http://dx.doi.org/10.1097/RHU.0000000000001471DOI Listing

Different Components of Subjective Well-being Are Associated With Chronic Nondisabling and Disabling Knee Pain: ELSA-Brasil Musculoskeletal Cohort.

J Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

From the Faculty of Medicine.

Background/objective: Chronic knee pain (CKP) is a common pain complaint in older adults that is often associated with disability. This study investigated the relationship between 2 components of subjective well-being (depressive symptoms and life satisfaction) and CKP phenotypes based on the presence of knee disability.

Methods: A cross-sectional study was performed at baseline of ELSA-Brasil Musculoskeletal cohort (2012-2014). Read More

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http://dx.doi.org/10.1097/RHU.0000000000001472DOI Listing

Rheumatic Diseases Associated With Posterior Reversible Encephalopathy Syndrome.

J Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

From the Division of Rheumatology, Rush University Medical Center.

Objective: Posterior reversible encephalopathy syndrome (PRES) is an acute neurological syndrome. There are many reports of PRES occurring in the setting of rheumatic diseases. However, it remains uncertain whether rheumatic diseases are truly a risk factor for PRES, as the literature consists of case reports and small clinical series. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001470DOI Listing

Bilateral swelling of the forearms revealing muscular sarcoidosis: a case-based review.

Clin Rheumatol 2020 Jun 27. Epub 2020 Jun 27.

Rheumatology Department, Mohammed V University, Rabat, Morocco.

Muscular sarcoidosis is rarely symptomatic and mainly affects proximal muscles of the lower extremities. However, the distal localization in the upper extremities is rare. We used systematic approach to analyze all relevant literature review and we identified only three cases of muscular sarcoidosis of the upper extremities. Read More

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http://dx.doi.org/10.1007/s10067-020-05259-1DOI Listing

Clinical image: chronic skin ulcers in a patient with rheumatoid arthritis on immunosuppressant therapy.

Clin Rheumatol 2020 Jun 26. Epub 2020 Jun 26.

Department of Internal Medicine, University of Iowa Hospitals & Clinics, 200 Hawkins Drive, SW34 GH, Iowa, IA, USA.

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http://dx.doi.org/10.1007/s10067-020-05251-9DOI Listing

Correction to: Late-onset Pneumocystis jirovecii pneumonia (PJP) in patients with ANCA-associated vasculitis.

Clin Rheumatol 2020 Jun 26. Epub 2020 Jun 26.

Renal Unit, Aberdeen Royal Infirmary, Aberdeen, UK.

The family name of the corresponding author on the original version of this article was incorrectly spelled as "Mariana Philipos". Read More

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http://dx.doi.org/10.1007/s10067-020-05242-wDOI Listing

Distinct gene network in skin lesion of patients with diffuse cutaneous systemic sclerosis.

Authors:
Jun Inamo

Clin Rheumatol 2020 Jun 25. Epub 2020 Jun 25.

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1007/s10067-020-05245-7DOI Listing

Serum levels of leptin, osteopontin, and sclerostin in patients with and without knee osteoarthritis.

Clin Rheumatol 2020 Jun 25. Epub 2020 Jun 25.

Department of Sports Medicine and Adult Reconstructive Surgery, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.

Objective: To investigate the relationship between leptin, osteopontin (OPN), sclerostin (SOST) and severity of knee osteoarthritis (KOA).

Methods: The study included 148 consecutive patients with knee OA and 101 non-KOA subjects enrolled in this cross-sectional study. All patients fulfilled the American College of Rheumatology criteria for primary knee OA. Read More

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http://dx.doi.org/10.1007/s10067-020-05150-zDOI Listing

A theory-based intervention to promote medication adherence in patients with rheumatoid arthritis: A randomized controlled trial.

Clin Rheumatol 2020 Jun 25. Epub 2020 Jun 25.

Social Determinants of Health Research Center, Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Shahid Bahounar BLV, Qazvin, 3419759811, Iran.

Introduction/objectives: Adherence to prescribed medication regimens is fundamental to the improvement and maintenance of the health of patients with rheumatoid arthritis. It is therefore important that interventions are developed to address this important health behavior issue. The aim of the present study was to design and evaluate a theory-based intervention to improve the medication adherence (primary outcome) among rheumatoid arthritis patients. Read More

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http://dx.doi.org/10.1007/s10067-020-05224-yDOI Listing

Potential and prognostic factor for belimumab-free remission in patients with systemic lupus erythematosus: a single-center retrospective analysis.

Clin Rheumatol 2020 Jun 24. Epub 2020 Jun 24.

Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan.

Belimumab is an effective and safe treatment option for systemic lupus erythematosus (SLE). However, data on treatment cessation are lacking. Thus, we investigated belimumab-free remission in SLE patients. Read More

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http://dx.doi.org/10.1007/s10067-020-05052-0DOI Listing

Diplopia and ocular pain due to orbital myositis.

Clin Rheumatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Rheumatology, Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Nuevo Leon, Mexico.

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http://dx.doi.org/10.1007/s10067-020-05147-8DOI Listing

Preconceived notions about biosimilars-a French experience.

Clin Rheumatol 2020 Jun 22. Epub 2020 Jun 22.

Law and Health Economics Department, Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité, 4 avenue de l'Observatoire, 75006, Paris, France.

Since the arrival of the first biosimilar monoclonal antibodies into the market, many information has been circulating, leading to preconceived notions for patients and healthcare professionals. In a pressing economic context and faced with a growing number of available biosimilars, we (clinician, patient association, biologist, pharmacists, health economists) propose to take stock by trying to distinguish facts from misconceptions. Read More

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http://dx.doi.org/10.1007/s10067-020-05229-7DOI Listing

Correction to: Anti-cyclic citrullinated peptide antibody in the cerebrospinal fluid in patients with rheumatoid arthritis who have central nervous system involvement.

Clin Rheumatol 2020 Jun 22. Epub 2020 Jun 22.

Department of Connective Tissue Diseases, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan.

The authors regret that the original published version of the above article contained errors. The authors requested that these be noted. Read More

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http://dx.doi.org/10.1007/s10067-020-05223-zDOI Listing

Similar risk of cardiovascular events in idiopathic inflammatory myopathy and rheumatoid arthritis in the first 5 years after diagnosis.

Clin Rheumatol 2020 Jun 22. Epub 2020 Jun 22.

Centre for Rheumatic Diseases, King's College London, London, UK.

Objectives: To estimate the incidence of cardiovascular (CV) events in idiopathic inflammatory myopathy (IIM) compared to patients with rheumatoid arthritis (RA) and the general population. To explore the contribution of traditional CV risk factors to any difference observed.

Methods: A retrospective matched population-based cohort study was conducted using UK Clinical Practice Research Datalink (CPRD) from 1987 to 2013. Read More

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http://dx.doi.org/10.1007/s10067-020-05237-7DOI Listing

LARS study: Latin American rheumatologist survey.

Clin Rheumatol 2020 Jun 22. Epub 2020 Jun 22.

Universidad de Especialidades Espíritu Santo, Guayaquil, Ecuador.

Background/objective: Latin America has scarce information related to rheumatologist's education, working conditions, productivity, and job satisfaction. The purpose of this survey was to describe the training and clinical practice characteristics of the rheumatology community in Latin America.

Methods: This is a cross-sectional study. Read More

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http://dx.doi.org/10.1007/s10067-020-05240-yDOI Listing

Holistic Treatment of Fibromyalgia Based on Physiopathology: An Expert Opinion.

J Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

From the Rheumatology Department, National Institute of Cardiology, Mexico City, Mexico.

Patients suffering from fibromyalgia have many vexing symptoms; in contrast, physicians do not have a logical physiopathological framework to explain the multiple complaints. The objective of this writing is to discuss a patient-centered holistic fibromyalgia therapy based on a coherent physiopathological model.The rationale proposing fibromyalgia as stress-related sympathetically maintained neuropathic pain syndrome has solid research foundations. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001455DOI Listing

Thai Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Outcomes and Risk Factors for Mortality.

J Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

From the Allergy and Rheumatology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, HatYai, Songkhla, Thailand.

Background/objective: Patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) have an increased risk of premature death. Different subtypes, predictors, and ethnicities may affect the overall survival. However, the overall survival of Thai AAV patients has not been reported. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001456DOI Listing

Kikuchi-Fujimoto Disease in a Young Hispanic Male.

J Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

Rheumatology, Allergy and Immunology, Virginia Commonwealth University, Richmond, VA.

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http://dx.doi.org/10.1097/RHU.0000000000001452DOI Listing

Reduction of Myeloperoxidase-Antineutrophil Cytoplasmic Antibody by Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis.

J Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

From the Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/RHU.0000000000001453DOI Listing

Ultrasonography Reliability in the Detection of Inflammatory and Structural Abnormalities: An Exercise in Multiple Joints.

J Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Rheumatology Department, Hospital Egas Moniz, Centro Hospitalar de Lisboa Ocidental. E.P.E., Lisboa.

Background: Ultrasonography is an image technique that allows rheumatologists to visualize structural and inflammatory changes within a joint. The objective of this study was to assess the interobserver and intraobserver reliability of musculoskeletal ultrasound (US) in the detection of inflammatory and destructive joint changes in patients with polyarthritis.

Methods: A Delphi exercise was undertaken to standardize and adapt the EULAR-OMERACT elementary US definitions of inflammatory lesions (effusion, synovial hypertrophy, power Doppler, bone erosions, and synovitis) for each joint. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001440DOI Listing

Sleep Disturbance in Scleroderma.

J Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

From the Mackenzie Evangelical School of Medicine of Paraná, Curitiba, Brazil.

Introduction: Sleep quality may be impaired in systemic scleroderma (SSc) patients and contribute to loss of life quality.

Aim: The aims of this study were to study the prevalence of sleep disturbance in SSc patients and its possible association with epidemiological, clinical and laboratory data, treatment used, and depression, and to verify the association of sleep disturbance and quality of life in this group of patients.

Methods: This is a cross-sectional study including 60 SSc patients. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001437DOI Listing

A Rare Cause of Microcrystalline Arthritis in a Young Adult.

J Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

From the Rheumatology Department, Unidade Local de Saúde do Alto Minho, Ponte de Lima.

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http://dx.doi.org/10.1097/RHU.0000000000001439DOI Listing

Serum Urate Levels of Hemodialyzed Renal Patients Revisited.

J Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Clinical Medicine Department, Miguel Hernandez University.

Objectives: The need of maintaining serum urate (SU)-lowering agents in hemodialysis (HD) patients is an understudied area that requires a review, as it is a common practice. The aims were to assess the SU reduction achieved under HD and to analyze the kinetics of SU in a week of intermittent HD.

Methods: The serum urate levels were prospectively determined before and after HD sessions in 96 consecutive patients with end-stage renal disease, and the average SU reduction was assessed. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001438DOI Listing

Comment on "Colchicine may not be effective in COVID-19 infection; it may even be harmful?"

Authors:
Senol Kobak

Clin Rheumatol 2020 Jun 20. Epub 2020 Jun 20.

Department of Internal Medicine and Rheumatology, Liv Hospital, Istinye University Faculty of Medicine, Canan sokak No. 5 Ulus, Istanbul, Turkey.

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http://dx.doi.org/10.1007/s10067-020-05233-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305478PMC

The clinical efficacy of urate-lowering therapy in acute gout: a meta-analysis of randomized controlled trials.

Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Department of general medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Background: Gout is a common chronic disease with a high recurrence rate. To date, the debate continues about the best time for using urate lowering therapy (ULT) during an acute gout attack.

Objective: This updated meta-analysis is designed to assess the clinical efficacy of ULT in the management of acute exacerbations of gout. Read More

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http://dx.doi.org/10.1007/s10067-020-05215-zDOI Listing

F-FDG PET/CT plays a unique role in the management of Takayasu arteritis patients with atypical manifestations.

Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Department of Hypertension, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, North Lishi Road, Xicheng District, Beijing, 100037, China.

Objective: The present study aimed to evaluate the value of F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) aiding in diagnosing and evaluating disease activity in Takayasu arteritis (TA) patients with atypical clinical manifestations.

Methods: A retrospective study of 22 TA patients was conducted. All the participants were classified into two groups. Read More

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http://dx.doi.org/10.1007/s10067-020-05028-0DOI Listing

A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab.

Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Department of Rheumatology and Immunology, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.

Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA). Tocilizumab was applied and intended to target both COVID-19 and RA. However, disease of this patient aggravated after usage of tocilizumab. Read More

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http://dx.doi.org/10.1007/s10067-020-05234-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303585PMC

Moyamoya syndrome related to systemic lupus erythematosus developing during pregnancy: a case-based review.

Clin Rheumatol 2020 Jun 19. Epub 2020 Jun 19.

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.

Moyamoya syndrome (MMS) is a chronic cerebrovascular disorder characterized by occlusion or stenosis of the internal carotid arteries with the formation of abnormal collateral vascular networks. Moreover, the development of MMS, which is a distinct category from "moyamoya disease," is attributed to the underlying disease, while some cases of MMS related to systemic lupus erythematosus (SLE) have been previously reported. Herein, we present the case of a 29-year-old Japanese woman with SLE in whom intracranial hemorrhage ascribable to MMS developed during pregnancy. Read More

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http://dx.doi.org/10.1007/s10067-020-05246-6DOI Listing

Spinal Urate Deposition in a Patient With Gout and Nonspecific Low Back Pain: Response to Initiation of Gout Therapy.

J Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

From the Department of Medicine, Division of Rheumatology, NYU Grossman School of Medicine.

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http://dx.doi.org/10.1097/RHU.0000000000001444DOI Listing

Marantic Endocarditis in a Long-Standing Untreated Rheumatoid Arthritis Patient.

J Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

From the Department of Medicine, University of California School of Medicine, Davis.

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http://dx.doi.org/10.1097/RHU.0000000000001441DOI Listing

Carotid Artery Dissection: A Rare Presenting Manifestation of Takayasu Arteritis.

J Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

From the Departments of Rheumatology and Allergy.

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http://dx.doi.org/10.1097/RHU.0000000000001446DOI Listing

A Meta-analysis and Systematic Review of Valvular Heart Disease in Systemic Lupus Erythematosus and Its Association With Antiphospholipid Antibodies.

J Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

From the John H. Stroger Hospital of Cook County, Chicago.

Background: Valvular heart disease (VHD) is a known cardiac manifestation of systematic lupus erythematosus (SLE). This systematic review aims to pool data from studies to estimate the frequency of valvular lesions in SLE patients. It also aims to demonstrate the association between VHD in SLE and antiphospholipid antibodies positivity. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001464DOI Listing

A Dramatic Presentation of Immune-Mediated Necrotizing Myopathy.

J Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

Division of Immunology, Department of Internal Medicine, University of Iowa Hospitals & Clinics, Iowa City, IA.

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http://dx.doi.org/10.1097/RHU.0000000000001443DOI Listing

Interleukin-29 and interleukin-28A induce migration of neutrophils in rheumatoid arthritis.

Clin Rheumatol 2020 Jun 15. Epub 2020 Jun 15.

Department of Rheumatology and Immunology, China-Japan Union Hospital of Jilin University, No.126 Xiantai Street, Changchun, Jilin, 130033, China.

Objectives: Type III Interferons, interleukin (IL)-29 and IL-28A, have been implicated in the inflammatory response of rheumatoid arthritis (RA). Increasing evidence suggests an important role of neutrophils in the pathogenesis of RA. However, the underlying mechanism remains unclear. Read More

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http://dx.doi.org/10.1007/s10067-020-05211-3DOI Listing

Multisystemic manifestations of IgA vasculitis.

Clin Rheumatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Chinese Medicine, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No. 56 Nanlishi Road, Beijing, 100045, China.

Immunoglobulin A vasculitis (IgAV), also known as Henoch-Schönlein Purpura, is one of the most common kind of systemic vasculitis in children, and due to the involvement of small blood vessels throughout the body, this disease can cause a variety of symptoms in different organs. Our aim was to review the data on various systemic manifestations of IgAV. A research of the literature was performed in PubMed database, utilizing the MeSH terms "IgA vasculitis" and "Henoch Schönlein Purpura". Read More

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http://dx.doi.org/10.1007/s10067-020-05166-5DOI Listing

Associations of FKBP4 and FKBP5 gene polymorphisms with disease susceptibility, glucocorticoid efficacy, anxiety, depression, and health-related quality of life in systemic lupus erythematosus patients.

Clin Rheumatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, No. 81, Meishan Rd, Shushan District, Hefei, 230032, Anhui, China.

Objectives: To explore the associations of FKBP4 and FKBP5 gene polymorphisms with disease susceptibility, glucocorticoid (GC) efficacy, anxiety, depression, and health-related quality of life (HRQOL) in systemic lupus erythematosus (SLE) patients.

Methods: All subjects were collected from the First and the Second Affiliated Hospital of Anhui Medical University in Hefei, China, during 2011 to 2015. In the case-control study, 541 SLE patients and 543 controls were recruited. Read More

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http://dx.doi.org/10.1007/s10067-020-05195-0DOI Listing

Urinary ferritin creatinine ratio, a potential biomarker for lupus nephritis activity.

Clin Rheumatol 2020 Jun 16. Epub 2020 Jun 16.

Department of Rheumatology and Immunology, First Affiliated Hospital, China Medical University, Shenyang, 110001, People's Republic of China.

Introduction/objective: Ferritin has gained increasing attention in systemic lupus erythematosus (SLE).This study aimed to investigate the clinical significance of urinary ferritin/creatinine ratio in lupus nephritis (LN).

Method: Samples from 62 SLE patients (35 with LN and 27 without LN) and 62 healthy controls were evaluated. Read More

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http://dx.doi.org/10.1007/s10067-020-05214-0DOI Listing

Non-anti-TNF biologic agents are associated with slower worsening of interstitial lung disease secondary to rheumatoid arthritis.

Clin Rheumatol 2020 Jun 16. Epub 2020 Jun 16.

Instituto de Investigación Biomédica de Málaga (IBIMA), 29010, Málaga, Spain.

Objectives: To analyze the effect of disease-modifying antirheumatic drugs (DMARDs) on the outcome of interstitial lung disease secondary to rheumatoid arthritis (RA-ILD).

Patients And Methods: We performed a multicenter, prospective, observational study of patients with RA-ILD receiving DMARDs between 2015 and 2017. The patients were assessed using high-resolution computed tomography and pulmonary function tests at baseline and at 24 months. Read More

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http://dx.doi.org/10.1007/s10067-020-05227-9DOI Listing

COVID-19 and Kawasaki disease: an analysis using Google Trends.

Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

Institute of Life Course and Medical Sciences, University of Liverpool, William Henry Duncan Building, 6 West Derby Street, Liverpool, L7 8TX, UK.

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http://dx.doi.org/10.1007/s10067-020-05231-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298164PMC

Ancestral contribution of the muscle-specific creatine kinase (CKM) polymorphism rs4884 in the knee osteoarthritis risk: a preliminary study.

Clin Rheumatol 2020 Jun 17. Epub 2020 Jun 17.

Synovial Fluid Laboratory, Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", Calzada México-Xochimilco 289, Colonia Arenal de Guadalupe, Tlalpan, 14389, Mexico City, Mexico.

Introduction/objectives: Articular cartilage and periarticular muscle tissues are strongly affected during knee osteoarthritis (OA). Creatine kinase (CK) is an enzyme expressed in several tissues, but the isoform CK-MM is specific of skeletal muscle, and its serum concentration is used as a biomarker of muscle damage. Genetic variants of the CKM gene have been associated with various pathologies, but to date, there are no reports of association with OA. Read More

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http://dx.doi.org/10.1007/s10067-020-05238-6DOI Listing
June 2020
1.774 Impact Factor

Colchicine as a possible therapeutic option in COVID-19 infection.

Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

Research Institute, Fundación Universitaria de Ciencias de la Salud, Institución, Cra. 19 N 8ª-32, Bogotá, Colombia.

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http://dx.doi.org/10.1007/s10067-020-05247-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301347PMC

The prevalence of fabella and its association with the osteoarthritic severity of the knee in Korea.

Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, 222-1 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Republic of Korea.

The clinical relevance of the fabella, a sesamoid bone, has recently been investigated. Although many studies have documented the prevalence of the fabella, few large-scale studies have been conducted in an Asian, especially Korean, population. We conducted a retrospective survey of Koreans to determine the prevalence and distribution of the fabella and its association with osteoarthritic severity of the knee. Read More

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http://dx.doi.org/10.1007/s10067-020-05078-4DOI Listing

PON-1 haplotype (-108C>T, L55M, and Q192R) modulates the serum levels and activity PONase promoting an atherogenic lipid profile in rheumatoid arthritis patients.

Clin Rheumatol 2020 Jun 18. Epub 2020 Jun 18.

Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, CP. 39090, Chilpancingo, Guerrero, México.

Introduction/objective: Paraoxonase 1 (PON1) promotes antioxidant and antiatherogenic activity related to the hydrolysis of oxidized lipids of low-density lipoproteins. In rheumatoid arthritis (RA) patients, it has been reported that low PON1 activity is related to an impaired lipid profile, increasing cardiovascular risk (CVR). The goal of this study was to analyze the effect of common PON1 polymorphisms and haplotypes on enzymatic activity, PON1 serum levels (PON1s), and lipid parameters related to atherogenic profile in RA patients. Read More

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http://dx.doi.org/10.1007/s10067-020-05218-wDOI Listing