6,139 results match your criteria Bacteroides Infection

Clearance of Clostridioides difficile Colonization Is Associated with Antibiotic-Specific Bacterial Changes.

mSphere 2021 May 5;6(3). Epub 2021 May 5.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

The gut bacterial community prevents many pathogens from colonizing the intestine. Previous studies have associated specific bacteria with clearing colonization across different community perturbations. However, those bacteria alone have been unable to clear colonization. Read More

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Dietary Fiber Drives IL-1β-Dependent Peritonitis Induced by via Activation of the NLRP3 Inflammasome.

J Immunol 2021 May 3;206(10):2441-2452. Epub 2021 May 3.

Laboratório de Imunologia Molecular e Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

Intestinal barrier is essential for dietary products and microbiota compartmentalization and therefore gut homeostasis. When this barrier is broken, cecal content overflows into the peritoneal cavity, leading to local and systemic robust inflammatory response, characterizing peritonitis and sepsis. It has been shown that IL-1β contributes with inflammatory storm during peritonitis and sepsis and its inhibition has beneficial effects to the host. Read More

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What we actually know about the pathogenicity of Bacteroides pyogenes.

Med Microbiol Immunol 2021 May 2. Epub 2021 May 2.

Department of Medical Microbiology, Medical University of Warsaw, Chalubinskiego 5 Str, 02-004, Warsaw, Poland.

The aim of the study was to evaluate the pathogenic potential of Bacteroides pyogenes, rarely identified in clinical laboratories anaerobic bacteria. To increase the knowledge about this poorly understood anaerobic microorganism, the study also includes cases of infections described so far in the literature. Only the use of 16S rRNA sequencing and mass spectrometry technique allowed the identification of B. Read More

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Protective Effects of Cinnamaldehyde on the Inflammatory Response, Oxidative Stress, and Apoptosis in Liver of -Challenged Mice.

Molecules 2021 Apr 16;26(8). Epub 2021 Apr 16.

State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China.

infection is associated with gastrointestinal disorder and cellular injury in the liver of both humans and animals. Cinnamaldehyde, the main component of essential oil from cinnamon, has been reported to have anti-inflammatory, anti-oxidative, and anti-apoptotic effects. However, it remains unknown whether cinnamaldehyde can alleviate infection-induced liver injury in mice. Read More

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Surveillance of Antimicrobial Susceptibility of Anaerobe Clinical Isolates in Southeast Austria: Group Is on the Fast Track to Resistance.

Antibiotics (Basel) 2021 Apr 21;10(5). Epub 2021 Apr 21.

Diagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, A 8010 Graz, Austria.

Anaerobic bacteria play an important role in human infections. spp. are some of the 15 most common pathogens causing nosocomial infections. Read More

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Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease.

Liver Int 2021 Apr 25. Epub 2021 Apr 25.

Department of Hepatology and Gastroenterology, Charité University Medicine, Campus Virchow Clinic and Campus Charité Mitte, Berlin, Germany.

Background And Aims: Non-alcoholic fatty liver disease (NAFLD) is a global health burden. Risk factors for disease severity include older age, increased body mass index (BMI), diabetes, genetic variants, dietary factors and gut microbiota alterations. However, the interdependence of these factors and their individual impact on disease severity remain unknown. Read More

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Microbiota of Endodontically Infected Primary and Permanent Teeth.

Pediatr Dent 2021 Mar;43(2):102-110

Dr. Ulger is an associate professor, Department of Medical Microbiology, Faculty of Medicine, Mersin University, Mersin, Turkey.

Differences in the endodontic microbiome of permanent and primary teeth during the mixed dentition period are still unknown. The purpose of this study was to examine bacterial diversity in endodontically infected primary and permanent teeth using 16S rRNA gene sequencing and the QIIME 2 (Quantitative Insights Into Microbial Ecology 2) bioinformatics pipeline. Microbial samples from endodontically infected primary ( equals 15) and permanent ( equals 15) maxillary or mandibular molar teeth were subjected to next-generation sequencing analysis based on examination of the hypervariable V3 to V4 region of the 16S rRNA gene. Read More

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Antibiotic resistance pattern of Bacteroides fragilis isolated from clinical and colorectal specimens.

Ann Clin Microbiol Antimicrob 2021 Apr 23;20(1):27. Epub 2021 Apr 23.

Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Poursina Street, Engelab-e-Eslami Avenue, Tehran, Iran.

Background: Bacteroides fragilis is a part of the normal gastrointestinal flora, but it is also the most common anaerobic bacteria causing the infection. It is highly resistant to antibiotics and contains abundant antibiotic resistance mechanisms.

Methods: The antibiotic resistance pattern of 78 isolates of B. Read More

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Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort.

Gut Microbes 2021 Jan-Dec;13(1):1-14

Department of Medical Biosciences, Pathology, Umeå University, Ireland.

Experimental evidence has implicated genotoxic () and enterotoxigenic (ETBF) in the development of colorectal cancer (CRC). However, evidence from epidemiological studies is sparse. We therefore assessed the association of serological markers of and ETBF exposure with odds of developing CRC in the European Prospective Investigation into Nutrition and Cancer (EPIC) study. Read More

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Gut Microbiome Changes with Acute Diarrheal Disease in Urban Versus Rural Settings in Northern Ecuador.

Am J Trop Med Hyg 2021 Apr 19. Epub 2021 Apr 19.

4School of Public Health, University of Washington, Seattle, Washington.

Previous studies have reported lower fecal bacterial diversity in urban populations compared with those living in rural settings. However, most of these studies compare geographically distant populations from different countries and even continents. The extent of differences in the gut microbiome in adjacent rural versus urban populations, and the role of such differences, if any, during enteric infections remain poorly understood. Read More

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The impact of urine microbiota in patients with lower urinary tract symptoms.

Ann Clin Microbiol Antimicrob 2021 Apr 15;20(1):23. Epub 2021 Apr 15.

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Introduction: Inflammation and infection are causative factors of benign prostatic hyperplasia (BPH). Urine is not sterile, and urine microbiota identified by DNA sequencing can play an important role in the development of BPH and can influence the severity of lower urinary tract symptoms (LUTS).

Materials And Methods: We collected mid-stream voided urine samples from BPH patients and control participants and stored them in a freezer at - 80 °C. Read More

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-Induced Necrotizing Fasciitis Complicated by Multidrug-Resistant Infection: Efficacy of Chemical Necrectomy Using 40% Benzoic Acid.

Int J Low Extrem Wounds 2021 Apr 15:15347346211004305. Epub 2021 Apr 15.

University Hospital Brno, Masaryk University, Jihomoravský, Czech Republic.

Necrotizing fasciitis is a life-threatening skin and soft tissue infection associated with high morbidity and mortality in adult patients. This infection can present as either type 1 infection caused by a mixed microflora (, , sp., and sp. Read More

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Association Between the Mode of Delivery and Infant Gut Microbiota Composition Up to 6 Months of Age: A Systematic Literature Review Considering the Role of Breastfeeding.

Nutr Rev 2021 Apr 9. Epub 2021 Apr 9.

Affiliation: L. Princisval, A.C. Coimbra, L. Crovesy, A.L. Ferreira, and G. Kac are with the Department of Social and Applied Nutrition, Federal University of Rio de Janeiro, Josué de Castro Nutrition Institute, Rio de Janeiro, RJ Brazil. B.L. Williams is with the Department of Epidemiology, Columbia University, Center for Infection and Immunity, New York, NY, USA. F. Rebelo is with the Oswaldo Cruz Foundation, National Institute of Women, Children and Adolescents Health Fernandes Figueira, Clinical Research Unit, Rio de Janeiro, RJ, Brazil.

Context: Cesarean section (CS), breastfeeding, and geographic location can influence the infant microbiota.

Objective: In this systematic review, evidence of the association between mode of delivery and infant gut microbiota up to 6 months of age was evaluated, as was the role of breastfeeding in this association, according to PRISMA guidelines.

Data Source: The Pubmed, Web of Science, Scopus, Embase, Medical Database, and Open Grey databases were searched. Read More

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Pharmacokinetics of Levornidazole Tablet in Healthy Chinese Subjects and Proposed Dosing Regimen Based on Pharmacokinetic/Pharmacodynamic Analysis.

Infect Dis Ther 2021 Apr 7. Epub 2021 Apr 7.

Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Introduction: Levornidazole is a novel nitroimidazole antimicrobial agent active against anaerobes. We aimed to investigate the pharmacokinetic (PK) profile of levornidazole after single and multiple oral doses of levornidazole tablets in healthy Chinese subjects and propose the dosing regimen based on pharmacokinetic/pharmacodynamic (PK/PD) analysis.

Methods: A single-center, randomized, double-blind, placebo-controlled study was conducted with a single ascending dose (250, 500, 1000, and 1500 mg) and multiple doses of 500 mg levornidazole q12h for 7 days. Read More

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Multicentre study of the burden of multidrug-resistant bacteria in the aetiology of infected diabetic foot ulcers.

Afr J Lab Med 2021 23;10(1):1261. Epub 2021 Mar 23.

Department of Medical Microbiology and Parasitology, Obafemi Awolowo University Teaching Hospitals, Ile-Ife, Nigeria.

Background: Infected diabetic foot ulcer (IDFU) is a public health issue and the leading cause of non-traumatic limb amputation. Very few published data on IDFU exist in most West African countries.

Objective: The study investigated the aetiology and antibacterial drug resistance burden of IDFU in tertiary hospitals in Osun state, Nigeria, between July 2016 and April 2017. Read More

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First case of abdominal infection caused by Bacteroides fluxus.

Anaerobe 2021 Apr 2;69:102363. Epub 2021 Apr 2.

Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de Las Nieves, Granada, Spain.

Bacteroides fluxus is a Gram-negative anaerobic bacillus isolated from human faeces in healthy individuals. Until now, this bacterium had not been involved in human diseases. We report the first case of abdominal infection due to this microorganism in an elderly patient. Read More

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Frequency and associated factors for carbapenem-non-susceptible Bacteroides fragilis group bacteria colonization in hospitalized patients: Case control study in a university hospital in Turkey.

Indian J Med Microbiol 2021 Mar 31. Epub 2021 Mar 31.

Department of Microbiology, Marmara University School of Medicine, Istanbul, Turkey. Electronic address:

Purpuse: The carbapenem-resistant Bacteroides fragilis group (CR-BFG) bacteria have been reported in several countries recently with increasing global attention. The high incidence of CR-BFG isolated from our hospitalized patients has become an important problem. Therefore, we aimed to determine the frequency and associated factors for intestinal colonization by carbapenem-non-susceptible BFG (CNS-BFG) among adult patients hospitalized at intensive care units, neurosurgery and internal medicine wards in our hospital. Read More

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Clindamycin-Based 3D-Printed and Electrospun Coatings for Treatment of Implant-Related Infections.

Materials (Basel) 2021 Mar 17;14(6). Epub 2021 Mar 17.

Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, SI 2000 Maribor, Slovenia.

This study presents the development and characterisation of two novel bioactive coatings deposited on TiAlV and AISI 316LVM substrates. The coatings were prepared using 3D printing and electrospinning. The 3D-printed coating consisted of the cellulose nanofibril suspension, alginate, and carboxymethylcellulose (CMC), while CMC and polyethylene oxide were used to prepare the electrospun coating. Read More

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Change in antimicrobial susceptibility of pathogens isolated from surgical site infections over the past decade in Japanese nation-wide surveillance study.

J Infect Chemother 2021 Mar 29. Epub 2021 Mar 29.

Department of Infection Control and Prevention, Kagoshima University Hospital, Kagoshima, Japan.

Inappropriate antimicrobial therapy for surgical site infections (SSIs) can lead to poor outcomes and an increased risk of antibiotic resistance. A nationwide survey was conducted in Japan from 2018 to 2019 to investigate the antimicrobial susceptibility of pathogens isolated from SSIs. The data were compared with those obtained in 2010 and 2014-2015 surveillance studies. Read More

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Whipworm-Associated Intestinal Microbiome Members Consistent Across Both Human and Mouse Hosts.

Front Cell Infect Microbiol 2021 11;11:637570. Epub 2021 Mar 11.

Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States.

The human whipworm infects 289 million people worldwide, resulting in substantial morbidity. Whipworm infections are difficult to treat due to low cure rates and high reinfection rates. Interactions between whipworm and its host's intestinal microbiome present a potential novel target for infection control or prevention but are very complicated and are identified using inconsistent methodology and sample types across the literature, limiting their potential usefulness. Read More

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Microbiota in Gut, Oral Cavity, and Mitral Valves Are Associated With Rheumatic Heart Disease.

Front Cell Infect Microbiol 2021 9;11:643092. Epub 2021 Mar 9.

Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Rheumatic heart disease refers to the long-term damage of heart valves and results from an autoimmune response to group A infection. This study aimed to analyze the microbiota composition of patients with rheumatic heart disease and explore potential function of microbiota in this disease. First, we revealed significant alterations of microbiota in feces, subgingival plaques, and saliva of the patients compared to control subjects using 16S rRNA gene sequencing. Read More

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L. johnsonii, L. plantarum, and L. rhamnosus alleviated Enterohaemorrhagic Escherichia coli-induced diarrhoea in mice by regulating gut microbiota.

Microb Pathog 2021 Mar 22;154:104856. Epub 2021 Mar 22.

College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China. Electronic address:

Enterohaemorrhagic Escherichia coli (EHEC) is a prominent foodborne pathogen that causes infectious intestinal diarrhoea. Lactobacillus is a recognized probiotic that inhibits intestinal pathogens and maintains the balance of the intestinal flora. The purpose of this study was to investigate the regulatory effects of three Lactobacillus strains, L. Read More

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Dissecting Individual Interactions between Pathogenic and Commensal Bacteria within a Multispecies Gut Microbial Community.

mSphere 2021 03 24;6(2). Epub 2021 Mar 24.

Warwick Medical School, University of Warwick, Coventry, United Kingdom

Interactions of commensal bacteria within the gut microbiota and with invading pathogens are critical in determining the outcome of an infection. While murine studies have been valuable, we lack models to monitor community responses to pathogens at a single-species level. We have developed a multispecies community of nine representative gut species cultured together as a mixed biofilm and tracked numbers of individual species over time using a quantitative PCR (qPCR)-based approach. Read More

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Nano-peroxidase a Promising Anti-inflammatory and Antibacterial Agent Against Bacteria and Inflammation Related to Colorectal Cancer.

J Gastrointest Cancer 2021 Mar 19. Epub 2021 Mar 19.

Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, Egypt.

Background: Colorectal cancer (CRC) is one of the most common causes of cancer death in the world. Although genes are considered the most importantcauses that contribute to CRC, the intestinal microorganisms are an important player. Recently, various studies ensured the role of microbial infection and the ensuing inflammation in colon cancer initiation and progression. Read More

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In-laboratory quality control of nutrients for automatic bacteriology analyzer YUNON®Labstar 50.

Klin Lab Diagn 2021 Mar;66(2):110-114

Regional Children's Clinical Hospital, clinical microbiology laboratory.

The quality of culture media for blood culture was checked: nutrient medium for children with an antibiotic neutralizer for the cultivation of aerobes, nutrient medium with an antibiotic neutralizer for the cultivation of anaerobes, a nutrient medium with an antibiotic neutralizer for the cultivation of aerobes, nutrient medium for the cultivation of aerobes UNONA® used in the automatic bacteriological analyzer JUNONA ®Labstar 50 (SCENKER Biological Technology Co., Ltd. China). Read More

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[Analysis of correlation between fecal and alveolar lavage fluid flora of ventilator-associated pneumonia patients based on 16S rRNA sequencing technology].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 Feb;33(2):169-173

Department of Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China. Corresponding author: Yang Xiaojun, Email:

Objective: To investigate the changes and correlation of intestinal and pulmonary microecological structures in patients with ventilator-associated pneumonia (VAP).

Methods: A prospective observational study was conducted. Thirty-one patients with VAP admitted to the department of critical care medicine of General Hospital of Ningxia Medical University from May 1st 2019 to May 1st 2020 were enrolled. Read More

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February 2021

Low Abundance in the Lower Gut Microbiota Is Associated With -Related Gastric Ulcer and Gastric Cancer.

Front Microbiol 2021 26;12:631140. Epub 2021 Feb 26.

Rajiv Gandhi Centre for Biotechnology, Trivandrum, India.

infection in stomach leads to gastric cancer, gastric ulcer, and duodenal ulcer. More than 1 million people die each year due to these diseases, but why most -infected individuals remain asymptomatic while a certain proportion develops such severe gastric diseases remained an enigma. Several studies indicated that gastric and intestinal microbiota may play a critical role in the development of the -associated diseases. Read More

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February 2021

Bacterial community analysis of purulent material from liver abscesses of crossbred cattle and Holstein steers fed finishing diets with or without tylosin.

J Anim Sci 2021 Apr;99(4)

Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506, USA.

Liver abscesses in feedlot cattle are polymicrobial infections. Culture-based studies have identified Fusobacterium necrophorum as the primary causative agent, but a number of other bacterial species are frequently isolated. The incidence of liver abscesses is highly variable and is affected by a number of factors, including cattle type. Read More

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The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases.

J Biol Chem 2021 Mar 5:100519. Epub 2021 Mar 5.

Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany. Electronic address:

Endo-β-N-acetylmuramidases, commonly known as lysozymes, are well-characterized antimicrobial enzymes that catalyze an endo-lytic cleavage of peptidoglycan; i.e. they hydrolyze the β-1,4-glycosidic bonds connecting N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc). Read More

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Protective Effects of 16 and Paenibacillus polymyxa 10 Against Infection in Broilers.

Front Immunol 2020 18;11:628374. Epub 2021 Feb 18.

Key Laboratory of Molecular Animal Nutrition of the Ministry of Education, College of Animal Sciences, Institute of Feed Science, Zhejiang University, Hangzhou, China.

This study aimed to investigate the protective effects of 16 (Lac16) and a 10 (BSC10) against (Cp) infection in broilers. A total of 720 one-day-old chicks were randomly divided into four groups. The control and Cp group were only fed a basal diet, while the two treatment groups received basal diets supplemented with Lac16 (1 × 10 cfu·kg) and BSC10 (1 × 10 cfu·kg) for 21 days, respectively. Read More

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February 2021