1,231 results match your criteria Bacterial Overgrowth Syndrome


Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

Front Immunol 2019 31;10:55. Epub 2019 Jan 31.

Fourth Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Hemophagocytic lymphohistocytosis (HLH) is characterized by fulminant cytokine storm leading to multiple organ dysfunction and high mortality. HLH is classified into familial (fHLH) and into secondary (sHLH). fHLH is rare and it is due to mutations of genes encoding for perforin or excretory granules of natural killer (NK) cells of CD8-lymphocytes. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365431PMC
January 2019

Risk factors for upper and lower functional gastrointestinal disorders in Persian Gulf War Veterans during and post-deployment.

Neurogastroenterol Motil 2019 Jan 29:e13533. Epub 2019 Jan 29.

Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.

Background: Gastroenteritis is a risk factor for irritable bowel syndrome (IBS), but its role in other functional gastrointestinal disorders (FGIDs) is less clear. The aim of this study was to determine the prevalence of FGIDs in Gulf War (GW) Veterans before, during, and after deployment and to determine whether gastroenteritis was a risk factor for upper and lower FGIDs.

Methods: The Veterans who served during the Persian GW were mailed validated questionnaires inquiring about their bowel habits, psychological and extra-intestinal symptoms, and quality of life (QOL). Read More

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http://doi.wiley.com/10.1111/nmo.13533
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http://dx.doi.org/10.1111/nmo.13533DOI Listing
January 2019
4 Reads

The Spectrum of Small Intestinal Bacterial Overgrowth (SIBO).

Curr Gastroenterol Rep 2019 Jan 15;21(1). Epub 2019 Jan 15.

Lynda K and David M Underwood Center for Digestive Disorders, Division of Gastroenterology and Hepatology, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX, USA.

Purpose Of Review: To critically review recent (past 3 years) literature on the definition, diagnosis, and management of small intestinal bacterial overgrowth (SIBO).

Recent Findings: While various series continue to illustrate the occurrence of SIBO in disease states where well-known risk factors for its occurrence are present (hypochlorhydria, disorders of intestinal structure or motor function, pancreatic insufficiency, and chronic liver disease, for example), the current challenge is in defining the limits of SIBO. Is SIBO truly common among those with "functional" gastrointestinal symptoms where there is no evidence of maldigestion or malabsorption; the original hallmarks of SIBO? Our attempts to address this question continue to be hampered by the limitations of our diagnostic tool kit. Read More

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http://dx.doi.org/10.1007/s11894-019-0671-zDOI Listing
January 2019
6 Reads

The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study.

Gastroenterol Res Pract 2018 6;2018:8791916. Epub 2018 Dec 6.

Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon, Republic of Korea.

Backgrounds: Recent studies suggest that diarrhea-predominant irritable bowel syndrome (IBS) is associated with intestinal bacterial microflora, colonic inflammation, and small intestinal bacterial overgrowth (SIBO). The purpose of this study was to evaluate the effect of a multistrain probiotic intake on these associated factors in patients with diarrhea-predominant IBS.

Methods: The recruited volunteers were adults who were diagnosed with diarrhea-predominant IBS according to the Rome III criteria. Read More

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http://dx.doi.org/10.1155/2018/8791916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304810PMC
December 2018

Changes in Fecal Calprotectin After Rifaximin Treatment in Patients With Nonconstipated Irritable Bowel Syndrome.

Am J Med Sci 2019 Jan 13;357(1):23-28. Epub 2018 Nov 13.

Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon, Gyeonggi-do, Republic of Korea. Electronic address:

Background: Fecal calprotectin, an indicator of colonic inflammation, is associated with nonconstipated irritable bowel syndrome. Rifaximin is an antibiotic used to treat nonconstipated irritable bowel syndrome. We performed a retrospective review of patient charts to investigate the changes in fecal calprotectin levels and intestinal symptoms following treatment with rifaximin in patients with nonconstipated irritable bowel syndrome with elevated fecal calprotectin. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029629183041
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http://dx.doi.org/10.1016/j.amjms.2018.11.004DOI Listing
January 2019
7 Reads

Bowel-associated dermatosis-arthritis syndrome (BADAS) in a patient with cystic fibrosis.

JAAD Case Rep 2019 Jan 5;5(1):37-39. Epub 2018 Dec 5.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1016/j.jdcr.2018.08.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287091PMC
January 2019

Bifidobacterium infantis M-63 improves mental health in victims with irritable bowel syndrome developed after a major flood disaster.

Benef Microbes 2018 Dec 10:1-10. Epub 2018 Dec 10.

1 School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu 16150, Kelantan, Malaysia.

Individuals in a community who developed irritable bowel syndrome (IBS) after major floods have significant mental health impairment. We aimed to determine if Bifidobacterium infantis M-63 was effective in improving symptoms, psychology and quality of life measures in flood-affected individuals with IBS and if the improvement was mediated by gut microbiota changes. Design was non-randomised, open-label, controlled before-and-after. Read More

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http://dx.doi.org/10.3920/BM2018.0008DOI Listing
December 2018
1 Read

Retracing our STEPs: Four decades of progress in intestinal lengthening procedures for short bowel syndrome.

Am J Surg 2018 Nov 27. Epub 2018 Nov 27.

Section of Pediatric Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, 06520, USA. Electronic address:

The surgical management of intestinal failure secondary to short bowel syndrome has undergone tremendous evolution in the last several decades. From the landmark description of an intestinal lengthening procedure by Bianchi in 1980 to the multidisciplinary modern care paradigm known as intestinal rehabilitation, innovative new treatments in this field have vastly improved patient outcomes. Initial attempts to treat short bowel syndrome surgically saw the birth of reversed intestinal segments, artificial valves and colonic transposition, all aimed at decreasing transit time and thus increasing absorption. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2018.11.025DOI Listing
November 2018
2 Reads

Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical study.

Transl Gastroenterol Hepatol 2018 25;3:72. Epub 2018 Sep 25.

Internal Medicine & Gastroenterology Department, University Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Background: Bloating is a common symptom reported by around 16% to 31% of the general population. Functional bloating is diagnosed in patients with recurrent symptoms of bloating who do not meet the diagnostic criteria of irritable bowel syndrome or other functional gastrointestinal disorders.

Methods: This double-blind, multicentre, randomised study compared the safety and efficacy of APT036 (xyloglucan plus tyndallized and ; Aprotecol) and simethicone in treating functional bloating in adults. Read More

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http://dx.doi.org/10.21037/tgh.2018.09.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256934PMC
September 2018
2 Reads

Prevalence of Clostridium perfringens netE and netF toxin genes in the feces of dogs with acute hemorrhagic diarrhea syndrome.

J Vet Intern Med 2019 Jan 30;33(1):100-105. Epub 2018 Nov 30.

Department of Clinical Veterinary Medicine, Clinic of Small Animal Internal Medicine, Ludwig Maximilian University of Munich, Munich, Germany.

Background: Recently, novel pore-forming toxin genes designated netE and netF were identified in a Clostridium perfringens type A strain isolated from a dog with acute hemorrhagic diarrhea.

Objectives: Pore-forming toxins could play an important role in the disease pattern of acute hemorrhagic diarrhea syndrome (AHDS) in dogs. Thus, we aimed to determine the prevalence of C. Read More

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http://dx.doi.org/10.1111/jvim.15361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335515PMC
January 2019
2 Reads

Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays.

Curr Top Med Chem 2018 ;18(19):1641-1655

Department of Psychiatry and Medical Psychology, Medical Faculty, Medical University of Plovdiv, Plovdiv, Bulgaria.

Background: Increased intestinal permeability with heightened translocation of Gramnegative bacteria, also known as "leaky gut", is associated with the pathophysiology of neuroimmune disorders, such as Major Depressive Disorder (MDD), Chronic Fatigue Syndrome (CSF) and (deficit) schizophrenia, as well as with general medical disorders, including irritable bowel syndrome. This review aims to summarize clinical biochemistry and molecular immunology tests that may aid in the recognition of leaky gut in clinical practice.

Methods: We searched online libraries, including PubMed/MEDLINE, Google Scholar and Scopus, with the key words "diagnosis" or "biomarkers" and "leaky gut", "bacterial translocation", and "intestinal permeability" and focused on papers describing tests that may aid in the clinical recognition of leaky gut. Read More

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http://dx.doi.org/10.2174/1568026618666181115100610DOI Listing
January 2018
15 Reads

Double-Blind Placebo-Controlled Study of Rifaximin and Lactulose Hydrogen Breath Test in Gulf War Veterans with Irritable Bowel Syndrome.

Dig Dis Sci 2018 Oct 28. Epub 2018 Oct 28.

Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.

Background: Irritable bowel syndrome (IBS) occurs in up to 33% of Gulf War (GW) Veterans. Alterations in gut microflora including small intestinal bacterial overgrowth (SIBO) during deployment may play a role in development of IBS. Rifaximin is a minimally absorbed antibiotic speculated to improve IBS symptoms, in part, by restoring normal gut microflora. Read More

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http://link.springer.com/10.1007/s10620-018-5344-5
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http://dx.doi.org/10.1007/s10620-018-5344-5DOI Listing
October 2018
4 Reads

Parkinson's Disease and Current Treatments for Its Gastrointestinal Neurogastromotility Effects.

Curr Treat Options Gastroenterol 2018 Dec;16(4):489-510

Carolinas Healthcare-Charlotte, UNC School of Medicine, Charlotte Campus, 1025 Morehead Medical Dr. Suite 300, Charlotte, NC, 28204, USA.

Purpose Of Review: Gastrointestinal disturbances are seen in nearly all patients with Parkinson's disease and lead to impaired quality of life, affect drug pharmacodynamics, and potentially worsen patient's existing motor fluctuations, leading to further disability. Recent evidence links abnormal accumulations of α-synuclein aggregates in the periphery (gut) as seen in the cortex which causes dysfunctions impacting every level of the gastrointestinal tract from the esophagus, to the stomach, small bowel, colon, and rectum and can even predate the onset of the central neurologic disorder itself. Many treatments exist for the clinical phenotypes that result from the autonomic dysfunction and neuropathy involved in this neurodegenerative disorder. Read More

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http://dx.doi.org/10.1007/s11938-018-0201-3DOI Listing
December 2018
10 Reads

Virginity-sparing management of blind hemivagina in obstructed hemivagina and ipsilateral renal anomaly syndrome.

Fertil Steril 2018 Oct;110(5):976-978

Department of Obstetrics and Gynecology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio.

Objectives: To demonstrate the hymen-sparing management of a blind hemivagina in obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome with the use of transrectal ultrasound (TRUS)-guided vaginoscopic septoplasty supported by pre- and postoperative diagnostics with the use of a novel ultrasound technique: 3-dimensional saline-solution infusion contrast sonovaginocervicography (3D-SVC) with virtual speculoscopy.

Design: Video presentation of surgical and ultrasound techniques.

Setting: University hospital and two private centers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00150282183057
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http://dx.doi.org/10.1016/j.fertnstert.2018.07.007DOI Listing
October 2018
4 Reads

Purple urine bag syndrome: A startling phenomenon of purple urine in a urine drainage bag. A primary care approach and literature review.

Authors:
Ywe Wong N Abdullah

Malays Fam Physician 2018 31;13(2):42-44. Epub 2018 Aug 31.

MBBS (Mal), MMed (FamMed) (Mal), Department of Primary Care Medicine, University of Malaya Medical Centre (UMMC) Malaysia.

Purple urine bag syndrome (PUBs) is a rare and startling phenomenon of purple discolouration in the urine or urinary catheter and bag. It is reported in chronically debilitated elderly patients, mostly in women on long-term urinary catheters. Its prevalence is strikingly more common in nursing home residents. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173963PMC

Therapeutic efficacy of amoxicillin and rifaximin in patients with small intestinal bacterial overgrowth and infection.

Prz Gastroenterol 2018 12;13(3):213-217. Epub 2018 Mar 12.

Department of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.

Introduction: Small intestinal bacterial overgrowth (SIBO) may coexist with infection, which can be the cause of chronic gastrointestinal complaints.

Aim: Evaluation of the therapeutic efficacy of amoxicillin and rifaximin in the treatment of these diseases.

Material And Methods: The lactulose hydrogen breath test (LHBT) and the urea breath test (C-UBT) were performed in 116 patients. Read More

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http://dx.doi.org/10.5114/pg.2018.74228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173078PMC
March 2018
3 Reads

Gut Microbiota Imbalance Can Be Associated with Non-malabsorptive Small Bowel Shortening Regardless of Blind Loop.

Obes Surg 2019 Feb;29(2):369-375

Department of Surgery and Experimental Research Laboratory, Federal University of Sao Paulo, Sao Paulo, Brazil.

Introduction: Some traditional bariatric surgery procedures may lead to functional gut shortening, which may unsettle the fine-tuned gastrointestinal physiology and affect gut microbiota balance.

Purpose: Evaluate the gut microbiota behavior in rat models facing gut shortening due to intestinal bypass.

Materials And Methods: Wistar rats (n = 17) were randomly distributed in three groups: (1) sham group (n = 5); (2) blind loop group (n = 6); and (3) resection group (n = 6). Read More

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http://dx.doi.org/10.1007/s11695-018-3540-1DOI Listing
February 2019

Short-course therapy for diarrhea-predominant irritable bowel syndrome: understanding the mechanism, impact on gut microbiota, and safety and tolerability of rifaximin.

Clin Exp Gastroenterol 2018 24;11:335-345. Epub 2018 Sep 24.

New Mexico VA Health Care System, Division of Gastroenterology and Hepatology, Albuquerque, NM, USA,

Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) disorder characterized by abdominal pain that occurs with defecation or alterations in bowel habits. Further classification is based on the predominant bowel habit: constipation-predominant IBS, diarrhea-predominant IBS (IBS-D), or mixed IBS. The pathogenesis of IBS is unclear and is considered multifactorial in nature. Read More

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http://dx.doi.org/10.2147/CEG.S167031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160288PMC
September 2018
3 Reads

Circular RNAs in Metabolic Diseases.

Adv Exp Med Biol 2018;1087:275-285

Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, School of Life Science, Shanghai University, Shanghai, China.

Metabolic diseases include diabetes mellitus (DM), obesity, metabolic syndrome, and non-alcoholic fatty liver disease (NAFLD). Circular RNA is a new type of RNA that is different from traditional linear RNA and has a closed loop structure. However, the function of circular RNA is not yet well elucidated in metabolic diseases. Read More

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http://dx.doi.org/10.1007/978-981-13-1426-1_22DOI Listing
February 2019
1 Read

Blind Pouch Syndrome in Gastrojejunostomy.

N Z Med J 2018 Aug 31;131(1481):74-77. Epub 2018 Aug 31.

Consultant General and Upper GI Surgeon, Department of General Surgery, Gisborne Hospital, Gisborne.

Blind pouch syndrome is a rare complication of a gastrojejunostomy. Its presentation may differ from blind pouches at other locations in that a small pouch can cause significant symptoms of mechanical obstruction before it is large enough to develop bacterial overgrowth. The effect of a small pouch may be overlooked at endoscopy and a high clinical index of suspicion is required. Read More

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August 2018
4 Reads

Coeliac disease.

Paediatr Int Child Health 2018 Aug 13:1-9. Epub 2018 Aug 13.

a Division of Gastroenterology and Hepatology , Beth Israel Deaconess Medical Center , Boston , Massachusetts , USA.

Coeliac disease (CD) develops in genetically susceptible individuals who, in response to unclear environmental triggers, develop an immune response triggered by gluten ingestion. It is now recognised as a global disease affecting about 0.7% of the world's population. Read More

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http://dx.doi.org/10.1080/20469047.2018.1504431DOI Listing
August 2018
5 Reads

Fecal Microbiota Alterations Associated With Diarrhea-Predominant Irritable Bowel Syndrome.

Front Microbiol 2018 25;9:1600. Epub 2018 Jul 25.

Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Altered gut microbiota are assumed to be involved in the pathogenesis of irritable bowel syndrome (IBS). However, gut microbiota alterations reported in different studies are divergent and sometimes even contradictory. To better elucidate the relationship between altered gut microbiota and IBS, we characterized fecal microbiota of diarrhea-predominant IBS (IBS-D) patients and further explored the effect of rifaximin on gut microbiota using bacterial 16S rRNA gene-targeted pyrosequencing. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2018.01600
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http://dx.doi.org/10.3389/fmicb.2018.01600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068233PMC
July 2018
4 Reads
3.940 Impact Factor

Remnant Small Bowel Length in Pediatric Short Bowel Syndrome and the Correlation with Intestinal Dysbiosis and Linear Growth.

J Am Coll Surg 2018 Oct 2;227(4):439-449. Epub 2018 Aug 2.

Department of Surgery, Washington University, School of Medicine, St Louis, MO. Electronic address:

Background: Pediatric short bowel syndrome (SBS) is a malabsorptive state placing patients at risk for malnutrition, dehydration, and bacterial overgrowth. These patients are often dependent on parenteral nutrition (PN) while intestinal adaptation is underway. The aim of this study was to characterize the effect of remnant small bowel length on the gut microbiome. Read More

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http://dx.doi.org/10.1016/j.jamcollsurg.2018.07.657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162148PMC
October 2018
4 Reads

Treatment of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review.

Rheumatology (Oxford) 2018 10;57(10):1802-1811

Department of Medicine, McMaster University, Hamilton, ON, Canada.

Objectives: Almost all patients with SSc have gastrointestinal manifestations. Small intestinal bacterial overgrowth (SIBO) occurs in 30-60% of patients and leads to malnutrition and impaired quality of life. Recent systematic reviews have reported efficacy of treatments for SIBO, but these are not specific to patients with SSc. Read More

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http://dx.doi.org/10.1093/rheumatology/key175DOI Listing
October 2018
33 Reads

Bacteria, Bones, and Stones: Managing Complications of Short Bowel Syndrome.

Nutr Clin Pract 2018 Aug 21;33(4):454-466. Epub 2018 Jun 21.

Department of Internal Medicine and Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.

Short bowel syndrome (SBS) occurs in patients who have had extensive resection. The primary physiologic consequence is malabsorption, resulting in fluid and electrolyte abnormalities and malnutrition. Nutrient digestion, absorption, and assimilation may also be diminished by disturbances in the production of bile acids and digestive enzymes. Read More

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http://dx.doi.org/10.1002/ncp.10113DOI Listing
August 2018
18 Reads

Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis.

Clin Transl Gastroenterol 2018 06 19;9(6):162. Epub 2018 Jun 19.

Division of Gastroenterology/Hepatology, Department of Internal Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Background: D-lactic acidosis is characterized by brain fogginess (BF) and elevated D-lactate and occurs in short bowel syndrome. Whether it occurs in patients with an intact gut and unexplained gas and bloating is unknown. We aimed to determine if BF, gas and bloating is associated with D-lactic acidosis and small intestinal bacterial overgrowth (SIBO). Read More

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http://www.nature.com/articles/s41424-018-0030-7
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http://dx.doi.org/10.1038/s41424-018-0030-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006167PMC
June 2018
37 Reads

Pharmacokinetic drug evaluation of rifaximin for treatment of diarrhea-predominant irritable bowel syndrome.

Expert Opin Drug Metab Toxicol 2018 Jul 22;14(7):753-760. Epub 2018 Jun 22.

a Department of Translational Medical Science , 'Federico II' University of Naples 80131 , Naples , Italy.

Introduction: Rifaximin is a poorly absorbable antibiotic with a broad-spectrum activity against both Gram-negative and -positive bacteria. It is active in the small intestine due to its high bile solubility, whereas in the aqueous environment of the colon, it shows limited efficacy against highly susceptible bacteria. These unique pharmacokinetic properties limit its systemic effects and can correct gut microflora imbalances. Read More

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http://dx.doi.org/10.1080/17425255.2018.1488964DOI Listing
July 2018
2 Reads

Small intestinal bacterial overgrowth (SIBO) and vitamin K-responsive coagulopathy: a previously unrecorded association.

BMJ Case Rep 2018 Jun 6;2018. Epub 2018 Jun 6.

Internal Medicine, Radiology Division, Ribeirao Preto Medical School-University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil.

A 17-year-old woman, with a history of three operations on the upper gut in early life and intermittent diarrhoea, presented with a history of epistaxis and leg ecchymosis for the previous 3 months. Initial investigation revealed mild anaemia, low serum albumin, moderately elevated aminotransferases and an exceedingly prolonged prothrombin time (PT) which was promptly shortened to normal by intravenous vitamin K. Additional investigations revealed a grossly abnormal glucose hydrogen breath test, a dilated duodenum and deficiencies of vitamins A, D and E. Read More

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http://dx.doi.org/10.1136/bcr-2017-223531DOI Listing
June 2018
3 Reads

[Development and features of infection in patients with acute-on-chronic liver failure and its influence on disease progression and prognosis].

Authors:
Z J Cao Q Xie

Zhonghua Gan Zang Bing Za Zhi 2018 Jan;26(1):6-9

Shanghai Jiaotong University School of Medicine, Ruijin Hospital, Shanghai 200025, China.

Acute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by acute decompensation of chronic liver disease associating with multiple organ failures and high short- term mortality. Patients with ACLF are highly susceptible to infection due to the pathophysiology features including immune function disorder (overlap of excessive inflammatory reaction and immune dysfunction), gut bacterial overgrowth/dysbiosis and translocation of gut microbiota/products. Appropriate empirical antibiotics plays a pivotal role in the management of ACLF with infection. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2018.01.003DOI Listing
January 2018
13 Reads

Resolution of late-onset heart and liver failures after reversion of jejuno-ileal bypass: a case report.

Scand J Gastroenterol 2018 Jun - Jul;53(7):891-894. Epub 2018 May 23.

c Unit of Surgery , University Hospital of Parma , Parma , Italy.

Objectives: Jejuno-ileal bypass (JIB) was a kind of bariatric surgery performed from 1960s to 1980s, able to induce sustainable weight loss by creating a surgical short bowel syndrome.

Materials And Methods: We report a case of an octogenarian woman who underwent in the early eighties this kind of surgery with consequent 40 kg weight loss. After 27 years, she first developed a reversible metabolic cardiomyopathy that began with signs and symptoms of heart failure. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1
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http://dx.doi.org/10.1080/00365521.2018.1474944DOI Listing
November 2018
16 Reads

Starch Tolerance and the Short Bowel.

J Pediatr Gastroenterol Nutr 2018 Jun;66 Suppl 3:S68-S71

Department of General Pediatrics and Neonatology, Justus Liebig University Giessen, Giessen.

Short bowel syndrome with intestinal failure is a rare disease with a massive impairment in quality of life, requiring a multidisciplinary team approach to medical, surgical, and nutritional therapy. Current pharmacological and surgical therapeutic options are limited; an important cornerstone is enteral and parenteral nutrition. The changed physiology of carbohydrate digestion plays a major role in the adaptation process and can be a target for specific enteral nutrition interventions. Read More

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http://dx.doi.org/10.1097/MPG.0000000000001962DOI Listing
June 2018
9 Reads

Prevalence and predictors of small intestinal bacterial overgrowth in irritable bowel syndrome: a systematic review and meta-analysis.

J Gastroenterol 2018 May 14. Epub 2018 May 14.

Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No.3 East Qingchun Road, Hangzhou, 310016, Zhejiang, China.

Background: The reported prevalence of small intestinal bacterial overgrowth (SIBO) among individuals with irritable bowel syndrome (IBS) is highly variable. The aim of the study is to estimate the prevalence and identify predictors of SIBO in IBS.

Methods: PubMed, Cochrane Library, and EMBASE through July 2017 were searched to identify studies evaluating the prevalence of SIBO in IBS. Read More

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http://dx.doi.org/10.1007/s00535-018-1476-9DOI Listing
May 2018
1 Read

[Dietetic treatment with fructose in a 5-year-old girl with recurrent D-lactic acidosis].

Nutr Hosp 2018 03 1;35(2):495-498. Epub 2018 Mar 1.

Servicio de Pediatría. Hospital Infantil Universitario Niño Jesús. Madrid..

D-lactic acidosis is an infrequent complication, mainly reported in patients with short bowel syndrome. It is characterized by recurrent episodes of encephalopathy with elevated serum D-lactic acid, usually associating metabolic acidosis. The presence of D-lactate-producing bacteria is necessary for the development of this complication. Read More

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http://dx.doi.org/10.20960/nh.1453DOI Listing
March 2018
1 Read

Evaluation of chronic diarrhea and irritable bowel syndrome with diarrhea in adults in the era of precision medicine.

Am J Gastroenterol 2018 May 1;113(5):660-669. Epub 2018 May 1.

Baylor University Medical Center, Dallas, TX, USA. Texas A & M College of Medicine, Dallas, TX, USA.

Chronic diarrhea is a common clinical problem, affecting roughly 5% of the population in any given year. Evaluation and management of these patients can be difficult due to the extensive differential diagnosis of this symptom. Many patients with chronic diarrhea have structural problems, such as inflammatory bowel disease or celiac disease, that can be readily identified. Read More

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http://dx.doi.org/10.1038/s41395-018-0032-9DOI Listing
May 2018
3 Reads

Bowel symptoms in patients that receive proton pump inhibitors. Results of a multicenter survey in Mexico.

Rev Gastroenterol Mex 2019 Jan - Mar;84(1):44-51. Epub 2018 Apr 17.

Alfa Wassermann S.A. de C.V., Ciudad de México, México; Medicina interna, Hospital Médica Sur, Ciudad de México, México.

Introduction: Proton pump inhibitors (PPIs) have been associated with small intestinal bacterial overgrowth (SIBO), which increases with prolonged PPI use, and SIBO has been associated with irritable bowel syndrome (IBS).

Objective: The aim of the present study was to study the prevalence of bowel symptoms in patients treated with PPIs in Mexico.

Methods: Gastroenterologists in 36 cities surveyed patients treated with PPIs, utilizing an ad hoc questionnaire to determine the presence of bowel symptoms and IBS. Read More

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http://dx.doi.org/10.1016/j.rgmx.2018.02.008DOI Listing
April 2018
1 Read

Clonidine modulates the activity of the subthalamic-supplementary motor loop: evidence from a pharmacological study combining deep brain stimulation and electroencephalography recordings in Parkinsonian patients.

J Neurochem 2018 Aug;146(3):333-347

Université de Lyon, Lyon, France.

Clonidine is an anti-hypertensive medication which acts as an alpha-adrenergic receptor agonist. As the noradrenergic system is likely to support cognitive functions including attention and executive control, other clinical uses of clonidine have recently gained popularity for the treatment of neuropsychiatric disorders like attention-deficit hyperactivity disorder or Tourette syndrome, but the mechanism of action is still unclear. Here, we test the hypothesis that the noradrenergic system regulates the activity of subthalamo-motor cortical loops, and that this influence can be modulated by clonidine. Read More

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http://doi.wiley.com/10.1111/jnc.14447
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http://dx.doi.org/10.1111/jnc.14447DOI Listing
August 2018
6 Reads

Restless legs syndrome in patients infected with Helicobacter pylori.

Neurol Res 2018 Jul 6;40(7):581-585. Epub 2018 Apr 6.

c Psychiatry, Psychosis Research Center , University of Social Welfare and Rehabilitation Sciences , Tehran , Iran.

Objective Although the etiology of restless legs syndrome (RLS) is yet to be discovered, some studies have mentioned the effect of infectious diseases in occurrence of RLS. This study aims to determine the association between common Helicobacter pylori (H. pylori) infection and occurrence of RLS. Read More

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https://www.tandfonline.com/doi/full/10.1080/01616412.2018.1
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http://dx.doi.org/10.1080/01616412.2018.1454704DOI Listing
July 2018
8 Reads

Correction to: Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

Probiotics Antimicrob Proteins 2018 Mar 28. Epub 2018 Mar 28.

Hepatogastroenterology Unit, 2nd Department of Internal Medicine-Propedeutic, Research Institute and Diabetes Center, National and Kapodistrian University of Athens, Athens, Greece.

The original version of this article contained mistakes, and the authors would like to correct them. The correct details are given below. Read More

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http://dx.doi.org/10.1007/s12602-018-9412-0DOI Listing
March 2018
15 Reads

Stoned-A Syndrome of D-Lactic Acidosis and Urolithiasis.

Nutr Clin Pract 2018 Dec 23;33(6):897-901. Epub 2018 Mar 23.

Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Short bowel syndrome (SBS) can lead to many complications related to the condition and its therapy. We describe 2 children with SBS who we believe are the second and third patients documented to have experienced both D-lactic acidosis and urolithiasis. We review aspects of these SBS complications and recent findings on the microbiome of patients with SBS that may predispose to these complications. Read More

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http://dx.doi.org/10.1002/ncp.10063DOI Listing
December 2018
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Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

Probiotics Antimicrob Proteins 2018 Mar 5. Epub 2018 Mar 5.

Hepatogastroenterology Unit, 2nd Department of Internal Medicine-Propedeutic, Research Institute and Diabetes Center, National and Kapodistrian University of Athens, Athens, Greece.

The effect of probiotics on small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome (IBS) has never been studied so far. In this prospective trial, five patients with IBS and SIBO and 21 patients with IBS without SIBO were administered an oral capsule containing Saccharomyces boulardii, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus plantarum (Lactolevure) every 12 h for 30 days. SIBO was defined by quantitative culture of the third part of the duodenum; IBS was defined by the Rome III criteria. Read More

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http://link.springer.com/10.1007/s12602-018-9401-3
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http://dx.doi.org/10.1007/s12602-018-9401-3DOI Listing
March 2018
8 Reads

[Review of the relation between gut microbiome, metabolic disease and hypertension].

Orv Hetil 2018 Mar;159(9):346-351

DVS Kft. Budapest.

Gut flora has personal characteristics for each individual, similar to the fingerprints, consisting of a special mixture of bacterial species living in the intestines, now referred to as the gut microbiome. There is a strong correlation between the loss of microbial diversity and the functional bowel disorders, obesity, type 2 diabetes and cardiovascular disease as well as many autoimmune disorders. With genetic testing of stool diversity of the gut microbiome and exact analysis of the species and phylogenetic classification of the gut flora, the changes of diversity can be identified and the overgrowth of some bacteria can be revealed. Read More

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http://dx.doi.org/10.1556/650.2018.30787DOI Listing
March 2018
3 Reads

Prevalence of Fructose Malabsorption in Patients With Irritable Bowel Syndrome After Excluding Small Intestinal Bacterial Overgrowth.

J Neurogastroenterol Motil 2018 Apr;24(2):307-316

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background/aims: Fructose malabsorption (FM) mimics symptoms of irritable bowel syndrome (IBS), and its prevalence has increased. Diagnosing FM in IBS is challenging because of its overlap with small intestinal bacterial overgrowth (SIBO). We assessed the prevalence of FM by comparing patients with IBS with asymptomatic control individuals after excluding SIBO using the glucose hydrogen breath test (HBT). Read More

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http://dx.doi.org/10.5056/jnm17044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885730PMC
April 2018
13 Reads
1 Citation
2.700 Impact Factor

Ileo-ileal fistula with severe malnutrition caused by strangulated ileus surgery while preserving ischemic ileum: A case report.

Int J Surg Case Rep 2018 28;43:4-8. Epub 2018 Jan 28.

Department of Surgery, Minami-Nara General Medical Center, 8-1 Fukugami, Oyodo-cho, Yoshino, 638-8551 Nara, Japan. Electronic address:

Introduction: Entero-enteric fistulas are rare complications that occur in patients with inflammatory bowel disease and other intestinal diseases. In this report, we present an ileo-ileal fistula accompanied by severe malnutrition caused by strangulated ileus surgery while preserving the ischemic ileum in a very elderly patient.

Case Presentation: A 90-year-old woman underwent emergency surgery without bowel resection for strangulated ileus in another hospital. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908384PMC
January 2018
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Nutritional Interventions in Chronic Intestinal Pseudoobstruction.

Gastroenterol Clin North Am 2018 Mar 6;47(1):209-218. Epub 2017 Dec 6.

Home Nutrition Support and Center for Gut Rehabilitation and Transplant, Center for Human Nutrition, Cleveland Clinic, 9500 Euclid Avenue/A100, Cleveland, OH 44195, USA.

Although chronic intestinal pseudo-obstruction (CIPO) is a rare disorder, it presents a wide spectrum of severity that ranges from abdominal bloating to severe gastrointestinal dysfunction. In the worst cases, patients may become dependent upon artificial nutrition via parenteral nutrition or choose to have an intestinal transplant. However, whatever the severity, a patient's quality of life can be seriously compromised. Read More

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http://dx.doi.org/10.1016/j.gtc.2017.09.005DOI Listing
March 2018
7 Reads

Small Intestinal Bacterial Overgrowth: Nutritional Implications, Diagnosis, and Management.

Gastroenterol Clin North Am 2018 Mar 7;47(1):193-208. Epub 2017 Dec 7.

Division of Gastroenterology and Hepatology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA. Electronic address:

Small intestinal bacterial overgrowth (SIBO), characterized by the presence of excessive bacteria in the small intestine, is typically described as a malabsorptive syndrome occurring in the context of gut stasis syndromes. SIBO is now considered to be a disorder associated with diverse clinical conditions without classic risk factors for SIBO and a cause of several nonspecific gastrointestinal and nongastrointestinal symptoms. Because there is currently no gold standard for diagnosing SIBO, its prevalence and role in the pathogenesis of other diseases remain uncertain; as does optimal treatment of patients with relapsing symptoms. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898553173012
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http://dx.doi.org/10.1016/j.gtc.2017.09.008DOI Listing
March 2018
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The characteristics of small intestinal bacterial overgrowth in patients with gallstone diseases.

J Gastroenterol Hepatol 2018 Aug 22;33(8):1477-1484. Epub 2018 Mar 22.

Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Background And Aim: Small intestinal bacterial overgrowth (SIBO) might be prevalent in gallstone disease, including cases involving cholecystectomy and gallstones. The study aimed to investigate the prevalence and characteristics of SIBO in patients with gallstone disease.

Methods: This prospective study evaluated 265 patients for gallstone disease (200, gallstones; 65, cholecystectomy) and 39 healthy controls. Read More

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http://doi.wiley.com/10.1111/jgh.14113
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http://dx.doi.org/10.1111/jgh.14113DOI Listing
August 2018
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Small Bowel Diverticulosis and Jejunal Perforation in Marfan Syndrome.

ACG Case Rep J 2018 17;5:e5. Epub 2018 Jan 17.

Center for Esophageal Disease and Swallowing, University of North Carolina School of Medicine, Chapel Hill, NC.

Marfan syndrome is an autosomal dominant disorder involving mutation in the gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal complications. We describe a man with Marfan syndrome with multiple small bowel diverticula leading to small intestinal bacterial overgrowth and recurrent small bowel perforations. Read More

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http://dx.doi.org/10.14309/crj.2018.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772063PMC
January 2018
4 Reads

Successful treatment of postural orthostatic tachycardia and mast cell activation syndromes using naltrexone, immunoglobulin and antibiotic treatment.

BMJ Case Rep 2018 Jan 11;2018. Epub 2018 Jan 11.

Department of Neurology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.

A patient with severe postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS) received immunotherapy with low-dose naltrexone (LDN) and intravenous immunoglobulin (IVIg) and antibiotic therapy for small intestinal bacterial overgrowth (SIBO). A dramatic and sustained response was documented. The utility of IVIg in autoimmune neuromuscular diseases has been published, but clinical experience with POTS is relatively unknown and has not been reported in MCAS. Read More

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http://dx.doi.org/10.1136/bcr-2017-221405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778345PMC
January 2018
41 Reads