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    26490 results match your criteria Bacterial Infections and Pregnancy

    1 OF 530

    Role of tumor necrosis factor-α in Gram-negative bacterial lipopolysaccharides induced implantation failure.
    Reprod Med Biol 2005 Mar 7;4(1):79-88. Epub 2005 Mar 7.
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, and.
    Gram-negative bacterial lipopolysaccharides (LPS) are known causative agents for pregnancy loss in mothers with genital tract infections. In this study, we attempt to test the role of tumor necrosis factor-α (TNF-α) in the normal physiological processes of preimplantation embryonic development and LPS induced pregnancy loss in mice. Since the preimplantation mouse embryos grow in an unattached state for a considerable period (day 1-4. Read More

    Adverse effects of maternal enterovirus infection on the pregnancy outcome: a prospective and retrospective pilot study.
    Virol J 2018 04 16;15(1):70. Epub 2018 Apr 16.
    Service de gynécologie et obstétrique and Risk in pregnancy university department, Hôpital Louis-Mourier, Assistance publique-Hôpitaux de Paris, 178, rue des Renouillers, 92700, Colombes, France.
    Background: Enteroviruses account for about one billion infections worldwide each year, the majority remain asymptomatic. Data on enterovirus infections during pregnancy appear to be very rare. Several cases have been reported in the literature of fetal and neonatal complications attributed to these viruses, but prospective data on these infections during pregnancy are not available. Read More

    Honey Bee as Alternative Medicine to Treat Eleven Multidrug-Resistant Bacteria Causing Urinary Tract Infection during Pregnancy.
    Sci Pharm 2018 Apr 13;86(2). Epub 2018 Apr 13.
    Department of Biology, Faculty of Biology, University 8 May 1945, 24000 Guelma, Algeria.
    Medicinal benefits of honey bee have been recognized in the medical community since ancient times as a remedy for many diseases and infections. This study aimed to investigate the susceptibility of 11 multidrug-resistant bacterial strains, isolated from urinary tract infections of pregnant women, to six honey samples collected from different localities in the east of Algeria. The evaluation of the antibacterial activity was performed by the well method followed by the broth dilution method using two-fold dilutions of each honey sample ranging from 2. Read More

    Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection.
    J Clin Invest 2018 Apr 9. Epub 2018 Apr 9.
    Department of Global Health, University of Washington, Seattle, Washington, USA.
    Thirteen percent of pregnancies result in preterm birth or stillbirth, accounting for fifteen million preterm births and three and a half million deaths annually. A significant cause of these adverse pregnancy outcomes is in utero infection by vaginal microorganisms. To establish an in utero infection, vaginal microbes enter the uterus by ascending infection; however, the mechanisms by which this occurs are unknown. Read More

    The Threat of Aerobic Vaginitis to Pregnancy and Neonatal Morbidity.
    Afr J Reprod Health 2017 Jun;21(2):108-118
    Microbial Endogenous Infections Studies, Department of Medical Biosciences, University of the Western Cape, Bellville, South Africa.
    Aerobic vaginitis (AV) is an endogenous opportunistic infection brought about by the disruption of the normal vaginal microbiota. Its early diagnosis and treatment during pregnancy may reduce the risk of negative pregnancy outcomes. The aim of this review was to report on the aerobic bacteria most prevalent in AV and to provide evidence of the threat of untreated AV on pregnancy outcomes. Read More

    [Features of local immunity in local inflammatory reactions in pregnant, depending on the implementation of intrauterine infection].
    Wiad Lek 2018 ;71(1 pt 2):168-172
    Kharkiv National Medical University, Kharkiv, Ukraine.
    Objective: Introduction: Vaginal protective systems function independently of other systemic mechanisms and impairments of local immune mechanisms of the vaginal mucosa are the cause of infectious disorders of the reproductive system The aim: To assess characteristics of local immunity in local inflammatory reactions in pregnant, depending on the implementation of intrauterine infection.

    Patients And Methods: Materials and methods: The study comprised Group 1 of pregnant women with the presence of bacterial infections with and without implementation of IUI, Group 2 with the presence of viral infections with and without implementation of IUI, Group 3 with the presence of infections of combined polyetiological structure with and without implementation of IUI and control group included pregnant women with physiological pregnancy. The study implied evaluation of the number of leukocytes in vaginal contents, concentration of IgA, IgM, IgG, sIgA, concentration of cytokines-IL-1 β , IL-6, IL-10, TNF- α in vaginal swabs. Read More

    Antepartum urinary tract infection and postpartum depression in Taiwan - a nationwide population-based study.
    BMC Pregnancy Childbirth 2018 Mar 27;18(1):79. Epub 2018 Mar 27.
    Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
    Background: Urinary tract infections (UTIs) are among the most common bacterial infections in pregnant women due to anatomic and physiologic changes in the female urinary tract during pregnancy, and antepartum UTIs can cause adverse pregnancy outcomes that may induce mental stress. There have only been a few studies, however, investigating antepartum UTIs and mental stress. As such, the present study was conducted in order to investigate the association between antepartum UTIs and postpartum depression (PPD). Read More

    Management of herpes zoster (shingles) during pregnancy.
    J Obstet Gynaecol 2018 Mar 22:1-8. Epub 2018 Mar 22.
    a Medical College of Georgia , Augusta University , Augusta , GA , USA.
    An infection with the varicella-zoster virus (VZV) causes both varicella and herpes zoster (HZ). Although rare, the development of HZ does occur during pregnancy. Maternal HZ does not result in increased foetal mortality, and the passage of VZV to the foetus rarely occurs. Read More

    [Treatment of perineal wounds during the post partum period: evaluation of whether or not antibiotic should be systematically prescribed].
    Pan Afr Med J 2017 16;28:144. Epub 2017 Oct 16.
    Département de Gynécologie et Obstétriques de la Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé I, Unité de Gynécologie et d'Obstétrique de l'Hôpital Central de Yaoundé, Cameroun.
    Introduction: Genital tract integrity is not always mantained during childbirth. No treatment protocol for post-partum perineal wounds (tears and episiotomies) existed in our Department, thus their management depends upon clinician. This study aimed to establish the role of antibiotic in the treatment of post-partum perineal wounds as well as the impact of antibioprophylaxis on wound healing and on prevention of infectious complications after repair. Read More

    Effect of maternal infection on gestational weight gain in an urban community of Uganda.
    Pan Afr Med J 2017 16;28:145. Epub 2017 Oct 16.
    Department of Biochemistry and Sports Science, School of Biolsciences, Makerere University, Kampala, Uganda.
    Introduction: Maternal infection has been associated with undesirable effects during pregnancy such as; hyperemesis gravidarum, anemia, intrauterine fetal growth restriction and miscarriage. Our aim was to document the effect of infection on gestational weight gain (GWG) in a low-income urban setting in Uganda.

    Methods: This was a prospective cohort study conducted in Kampala between May 2012 and May 2013. Read More

    [Causes of abortion in horses - overview of the literature and own evaluations].
    Tierarztl Prax Ausg G Grosstiere Nutztiere 2018 Feb 21;46(1):35-42. Epub 2018 Feb 21.
    The aim of this study was to summarize the current status of the possible causes, clinical symptoms and pathogenesis of abortion in the mare and to evaluate the frequency of varying causes of abortion in German thoroughbred breeding. An analysis of the literature using electronic libraries, journals and textbooks was performed. In addition, the results of examinations of 123 abortions of thoroughbred breeding in central Germany were evaluated. Read More

    [Second Austrian consensus on the safe use of anti-TNFα-antibodies in patients with inflammatory bowel diseases].
    Z Gastroenterol 2018 03 12;56(3):275-302. Epub 2018 Mar 12.
    Universitätsklinik für Innere Medizin III, Klinische Abteilung für Gastroenterologie und Hepatologie, Medizinische Universität Wien, Wien.
    Anti-TNFα-antibodies have revolutionized the therapy of inflammatory bowel diseases and other immune-mediated inflammatory diseases. Due to the increasing application of these substances, the Working Group of Inflammatory Bowel Diseases of the Austrian Association of Gastroenterology and Hepatology intended to update their consensus report on the safe use of Infliximab (published in 2010) and to enlarge its scope to cover all anti-TNFα-antibodies. The present consensus report summarizes the current evidence on the safe use of anti-TNFα-antibodies and covers the following topics: general risk of infection, bacterial infections (i. Read More

    Aminomethyl spectinomycins as therapeutics for drug-resistant gonorrhea and chlamydial co-infections.
    Antimicrob Agents Chemother 2018 Feb 26. Epub 2018 Feb 26.
    Microbiotix, Inc., Worcester, MA, USA.
    Bacterial sexually transmitted infections are widespread and common, with (gonorrhea) and (chlamydia) being the two most frequent causes. If left untreated, both infections can cause pelvic inflammatory disease, infertility, ectopic pregnancy and other sequelae. The recommended treatment for gonorrhea is ceftriaxone plus azithromycin (to empirically treat chlamydial co-infections). Read More

    Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term.
    J Matern Fetal Neonatal Med 2018 Mar 12:1-9. Epub 2018 Mar 12.
    c Fred Hutchinson Cancer Research Center , Seattle, Washington , DC , USA.
    Background: The majority of early preterm births are associated with intrauterine infections, which are thought to occur when microbes traffic into the uterus from the lower genital tract and seed the placenta. Bacterial vaginosis (BV) is associated with heterogeneous bacterial communities in the vagina and is linked to preterm birth. The extent to which trafficking into the uterus of normal and BV-associated vaginal bacteria occurs is unknown. Read More

    Antibiotics for treating gonorrhoea in pregnancy.
    Cochrane Database Syst Rev 2018 02 21;2:CD011167. Epub 2018 Feb 21.
    Departamento de Obstetricia y Ginecología, Universidad de Carabobo, Urbanización Fundación Mendoza calle 19, 5ta etapa N° 22-40, Valencia, Estado Carabobo, Venezuela, 2001.
    Background: Gonorrhoea is a sexually transmitted infection that is caused by Neisseria gonorrhoeae, and is a major public health challenge today. N gonorrhoeae can be transmitted from the mother's genital tract to the newborn during birth, and can cause gonococcal ophthalmia neonatorum as well as systemic neonatal infections. It can also cause endometritis and pelvic sepsis in the mother. Read More

    Prevalence of Streptococcus agalactiae colonization in pregnant women from the 18th Health Region of Paraná State.
    Rev Inst Med Trop Sao Paulo 2018 15;60:e2. Epub 2018 Feb 15.
    Departamento de Pós Graduação em Ciências da Saúde, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
    Introduction The aim of this study was to determine the prevalence of GBS colonization in pregnant women in a public health service. Methods A study of 496 pregnant women at 35-37 gestational weeks was conducted from September 2011 to March 2014 in 21 municipalities of the 18th Health Region of Paraná State. Vaginal and anorectal samples of each woman were plated on sheep blood agar, and in HPTH and Todd-Hewitt enrichment broths. Read More

    Haemolytic-uremic syndrome due to infection with adenovirus: A case report and literature review.
    Medicine (Baltimore) 2018 Feb;97(7):e9895
    Lucian Blaga University of Sibiu, Faculty of Medicine Sibiu, Romania.
    Rationale: Haemolytic-uremic syndrome is a rare but serious complication of bacterial and viral infections, which is characterized by the triad of: acute renal failure, microangiopathic haemolytic anemia and thrombocytopenia, sometimes severe, requiring peritoneal dialysis. In Europe, hemolytic-uremic syndrome (HUS) in paediatric pathology is primarily caused by Shiga toxin-producing Escherichia coli (STEC) O157, followed by O26. Beside these etiologies, there are other bacterial and viral infections, and also noninfectious ones that have been associated to lead to HUS as well: in the progression of neoplasia, medication-related, post-transplantation, during pregnancy or associated with the antiphospholipid syndrome, systemic lupus erythematosus or family causes with autosomal dominant or recessive inheritance. Read More

    Human cervical mucus plugs exhibit insufficiencies in antimicrobial activity towards Group B Streptococcus.
    J Infect Dis 2018 Feb 7. Epub 2018 Feb 7.
    Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States of America.
    Preterm birth is a leading cause of neonatal mortality and lacks an effective therapy. Ascending microbial infections from the lower genital tract lead to infection of the placenta, amniotic fluid and fetus causing preterm birth or stillbirth. Directly in the path of an ascending infection is the cervical mucus plug (CMP), a dense mucoid structure in the cervical canal with potential antimicrobial properties. Read More

    Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models.
    Sci Rep 2018 Feb 7;8(1):2593. Epub 2018 Feb 7.
    GSK, Siena, Italy.
    Group B Streptococcus (GBS) is a normal inhabitant of recto-vaginal mucosae in up to 30% of healthy women. Colonization is a major risk factor for perinatal infection which can lead to severe complications such as stillbirth and neonatal invasive disease. Intra-partum antibiotic prophylaxis in colonized women is a safe and cost-effective preventive measure against early-onset disease in the first days of life, but has no effect on late-onset manifestations or on early maternal infection. Read More

    Urinary tract infection during pregnancy: current concepts on a common multifaceted problem.
    J Obstet Gynaecol 2018 Feb 6:1-6. Epub 2018 Feb 6.
    a 3rd Department of Obstetrics and Gynaecology , Aristotle University of Thessaloniki , Thessaloniki , Greece.
    Urinary tract infections (UTIs) are the most common bacterial infection in pregnancy, increasing the risk of maternal and neonatal morbidity and mortality. Urinary tract infections may present as asymptomatic bacteriuria, acute cystitis or pyelonephritis. Escherichia coli is the most common pathogen associated with both symptomatic and asymptomatic bacteriuria. Read More

    The global maternal sepsis study and awareness campaign (GLOSS): study protocol.
    Reprod Health 2018 Jan 30;15(1):16. Epub 2018 Jan 30.
    UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
    Background: Maternal sepsis is the underlying cause of 11% of all maternal deaths and a significant contributor to many deaths attributed to other underlying conditions. The effective prevention, early identification and adequate management of maternal and neonatal infections and sepsis can contribute to reducing the burden of infection as an underlying and contributing cause of morbidity and mortality. The objectives of the Global Maternal Sepsis Study (GLOSS) include: the development and validation of identification criteria for possible severe maternal infection and maternal sepsis; assessment of the frequency of use of a core set of practices recommended for prevention, early identification and management of maternal sepsis; further understanding of mother-to-child transmission of bacterial infection; assessment of the level of awareness about maternal and neonatal sepsis among health care providers; and establishment of a network of health care facilities to implement quality improvement strategies for better identification and management of maternal and early neonatal sepsis. Read More

    Applications for Bacteriophage Therapy during Pregnancy and the Perinatal Period.
    Front Microbiol 2017 11;8:2660. Epub 2018 Jan 11.
    Division of Obstetrics and Gynecology, School of Medicine, The University of Western Australia, Crawley, WA, Australia.
    Pregnant women and their unborn children are a population that is particularly vulnerable to bacterial infection. Physiological changes that occur during pregnancy affect the way women respond to such infections and the options that clinicians have for treatment. Antibiotics are still considered the best option for active infections and a suitable prophylaxis for prevention of potential infections, such as vaginal/rectal colonization prior to birth. Read More

    Invasive bacterial disease trends and characterization of group B streptococcal isolates among young infants in southern Mozambique, 2001-2015.
    PLoS One 2018 19;13(1):e0191193. Epub 2018 Jan 19.
    Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, United States of America.
    Background: Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease (IBD) trends among infants <90 days in rural Mozambique during 2001-2015, with a focus on GBS epidemiology and strain characteristics. Read More

    Colonization of the cervicovaginal space with Gardnerella vaginalis leads to local inflammation and cervical remodeling in pregnant mice.
    PLoS One 2018 18;13(1):e0191524. Epub 2018 Jan 18.
    Maternal Child Health Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    The role of the cervicovaginal (CV) microbiome in regulating cervical function during pregnancy is poorly understood. Gardnerella vaginalis (G. vaginalis) is the most common bacteria associated with the diagnosis of bacterial vaginosis (BV). Read More

    A silent epidemic: the prevalence, incidence and persistence of Mycoplasma genitalium among young, asymptomatic high-risk women in the United States.
    Clin Infect Dis 2018 Jan 12. Epub 2018 Jan 12.
    Department of Medicine, Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill.
    Background: Mycoplasma genitalium (MG) is a sexually transmitted infection (STI) that can result in pelvic inflammatory disease and adverse pregnancy outcomes. We analyzed data collected from a prospective study of asymptomatic bacterial vaginosis (BV) to determine the natural history of MG.

    Methods: Women aged 15-25 years, with ≥2 STI risk factors and asymptomatic BV were recruited from 10 sites throughout the United States. Read More

    Antibiotics Dispensed to Privately Insured Pregnant Women with Urinary Tract Infections - United States, 2014.
    MMWR Morb Mortal Wkly Rep 2018 Jan 12;67(1):18-22. Epub 2018 Jan 12.
    Urinary tract infections (UTIs) occur in about 8% of pregnant women, and untreated UTIs can have serious consequences, including pyelonephritis, preterm labor, low birth weight, and sepsis (1). Pregnant women are typically screened for UTIs during early pregnancy, and those with bacteriuria are treated with antibiotics (1,2). Antibiotic stewardship is critical to improving patient safety and to combating antibiotic resistance. Read More

    Surveillance of listeriosis in the Tel Aviv District, Israel, 2010-2015.
    Epidemiol Infect 2018 Feb 8;146(3):283-290. Epub 2018 Jan 8.
    Central Laboratories,Israel Ministry of Health,POB 34410,Jerusalem,94467,Israel.
    This study analyses the epidemiologic, clinical and molecular findings of all culture-confirmed cases of listeriosis notified from 2010 to 2015 in the Tel Aviv District, which is known to have high rates of listeriosis. All clinical isolates of Listeria monocytogenes were subtyped using two-enzyme pulsed-field gel electrophoresis. During the studied period, 102 cases of listeriosis were notified, including 23 pregnancy-associated cases (23%). Read More

    Combined evaluation of sexually transmitted infections in HIV-infected pregnant women and infant HIV transmission.
    PLoS One 2018 5;13(1):e0189851. Epub 2018 Jan 5.
    David Geffen UCLA School of Medicine, Los Angeles, CA, United States of America.
    Background: Sexually transmitted infections (STIs) including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP), and cytomegalovirus (CMV) may lead to adverse pregnancy and infant outcomes. The role of combined maternal STIs in HIV mother-to-child transmission (MTCT) was evaluated in mother-infant pairs from NICHD HPTN 040.

    Methodology: Urine samples from HIV-infected pregnant women during labor were tested by polymerase chain reaction (PCR) for CT, NG, and CMV. Read More

    Non-protective immunity against tetanus in primiparous women and newborns at birth in rural and urban settings in Ibadan, Nigeria.
    Pan Afr Med J 2017 23;27(Suppl 3):26. Epub 2017 Jun 23.
    Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
    Introduction: Nigeria remains among the few countries that are yet to achieve eradication of neonatal tetanus in the world despite the availability of an effective vaccine. This study investigated immunity against tetanus in primiparous mothers and neonates at birth, and identified associated factors.

    Methods: This cross-sectional study involved consecutive selection of 244 primiparous mother-neonate pairs (119 from rural areas, 125 from urban areas, 137 male neonates and 107 female neonates) delivered at primary healthcare facilities in Ibadan, Nigeria Socio-demographic characteristics, obstetric history, immunisation and birthweight were obtained from mothers by interview. Read More

    Strategies to increase immunization coverage of tetanus vaccine among women in Sub Saharan Africa: a systematic review.
    Pan Afr Med J 2017 22;27(Suppl 3):25. Epub 2017 Jun 22.
    Ministry of Public Health, Yaoundé, Cameroon.
    World Health Organization (WHO) estimated in 2013 that 49,000 deaths all over the world were caused by neonatal tetanus. Only as recently as the year 2000, neonatal tetanus was a public health problem in 59 countries, but since then it has been eliminated in 36 of the countries concerned. The objective of this piece of work, therefore, was to investigate which strategies intended to increase demand for vaccination are effective in increasing anti-tetanus vaccination coverage of women in Sub Saharan Africa. Read More

    Progress towards achieving and maintaining maternal and neonatal tetanus elimination in the African region.
    Pan Afr Med J 2017 22;27(Suppl 3):24. Epub 2017 Jun 22.
    Centers for Disease Control and Prevention, Global Immunization Division, Atlanta, GA, USA.
    Despite the availability of effective tetanus prevention strategies, as of 2016, Maternal and Neonatal Tetanus Elimination (MNTE) has not yet been achieved in 18 countries globally. In this paper, we review the status of MNTE in the World Health Organization African Region (AFR),and provide recommendations for achieving and maintaining MNTE in AFR. As of November 2016, 37 (79%) AFR countries have achieved MNTE, with 10 (21%) countries remaining. Read More

    Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens.
    Vaccines (Basel) 2017 Dec 25;6(1). Epub 2017 Dec 25.
    Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA.
    is the most common cause of bacterial sexually transmitted infections worldwide. While infections resolve with antibiotic treatment, this is often neglected in women due to frequent asymptomatic infections, leading to disease progression and severe sequelae (pelvic inflammatory disease, ectopic pregnancy, infertility). Development of a vaccine against is crucial. Read More

    Serological prevalence of Coxiella burnetii in dairy goats and ewes diagnosed with adverse pregnancy outcomes in Greece.
    Ann Agric Environ Med 2017 Dec 19;24(4):702-705. Epub 2017 Dec 19.
    Laboratory of Animal Husbandry, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.
    Introduction: Coxiella burnetii is an obligatory intracellular bacterial pathogen causing the zoonotic disease Q fever. The most common reservoirs of C. burnetii are wild mammals, birds and ticks. Read More

    Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial.
    BMC Infect Dis 2017 12 28;17(1):799. Epub 2017 Dec 28.
    London School of Hygiene and Tropical Medicine, London, UK.
    Background: Vertical transmission can result in neonatal infection and disease. Reducing the transmission of bacterial pathogens from mother to infant may be an effective means of preventing neonatal infection, including bacterial conjunctivitis.

    Methods: In a double-blind, randomized trial, we assessed the effect of administering a single dose of oral azithromycin to women in labour on bacterial colonization of the neonate. Read More

    Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants Used for Treatment of Foot, Ankle, and Lower Leg Fractures: A Randomized Clinical Trial.
    JAMA 2017 12;318(24):2438-2445
    Trauma Unit, Department of Surgery, Academic Medical Center Amsterdam, the Netherlands.
    Importance: Following clean (class I, not contaminated) surgical procedures, the rate of surgical site infection (SSI) should be less than approximately 2%. However, an infection rate of 12.2% has been reported following removal of orthopedic implants used for treatment of fractures below the knee. Read More

    The magnitude of syphilis: from prevalence to vertical transmission.
    Rev Inst Med Trop Sao Paulo 2017 Dec 21;59:e78. Epub 2017 Dec 21.
    Universidade do Estado do Rio de Janeiro, Faculdade de Ciências Médicas, Rio de Janeiro, Rio de Janeiro, Brazil.
    Introduction: In 2013, the World Health Organization (WHO) reported that 1.9 million pregnant women were infected with syphilis worldwide, of which 66.5% had adverse fetal effects in cases of untreated syphilis. Read More

    Development of a Chlamydia trachomatis vaccine for urogenital infections: novel tools and new strategies point to bright future prospects.
    Expert Rev Vaccines 2018 Jan 21;17(1):57-69. Epub 2017 Dec 21.
    b Faculty of Science, Health, Education and Engineering , University of the Sunshine Coast , Maroochydore DC , Australia.
    Introduction: The "cloaked" bacterial pathogen that is Chlamydia trachomatis continues to cause sexually transmitted infections (STIs) that adversely affect the health and well-being of children, adolescents and adults globally. The reproductive disease sequelae follow unresolved or untreated chronic or recurrent asymptomatic C.trachomatis infections of the lower female genital tract (FGT) and can include pelvic pain, pelvic inflammatory disease (PID) and ectopic pregnancy. Read More

    The clinical impact of antimicrobial resistance genomics in competition with she-camels recurrent mastitis metabolomics due to heterogeneous field isolates.
    Vet World 2017 Nov 20;10(11):1353-1360. Epub 2017 Nov 20.
    Department of Food Hygiene, Animal Health Research Institute, Agriculture Research Centre, Dokki, Giza, Egypt.
    Background And Aim: Recently, cases of mastitis refractory to treatment have been reported frequently. There are limited routine laboratory investigations on Camelidae infections. Mastitis has been estimated to affect more than 25% of lactating she-camel with up to 70% milk loss. Read More

    Effects of ciprofloxacin and quercetin on fetal brain development: a biochemical and histopathological study.
    J Matern Fetal Neonatal Med 2018 Jan 10:1-9. Epub 2018 Jan 10.
    e Department of Biochemistry, Faculty of Medicine , Inonu University , Malatya , Turkey.
    Purpose: Teratogens cause birth defects and malformations while human development is being completed. In pregnancy, urinary tract infection (UTI) is a common health problem caused by bacteria. The fluoroquinolones such as ciprofloxacin, levofloxacin, moxifloxacin, and gemifloxacin can treat various types of bacterial infections successfully. Read More

    Factors associated with four atypical cases of congenital syphilis in England, 2016 to 2017: an ecological analysis.
    Euro Surveill 2017 Dec;22(49)
    HIV & STI Department, Public Health England, Colindale, London, United Kingdom.
    Four isolated cases of congenital syphilis born to mothers who screened syphilis negative in the first trimester were identified between March 2016 and January 2017 compared with three cases between 2010 and 2015. The mothers were United Kingdom-born and had no syphilis risk factors. Cases occurred in areas with recent increases in sexually-transmitted syphilis among women and men who have sex with men, some behaviourally bisexual, which may have facilitated bridging between sexual networks. Read More

    Periapical infection may affect birth outcomes via systemic inflammation.
    Oral Dis 2017 Dec 12. Epub 2017 Dec 12.
    Center for Child Health Research, University of Tampere Faculty of Medicine and Life Sciences and Tampere University Hospital, Tampere, Finland.
    Objectives: Maternal dental periapical infections are associated with preterm birth and intrauterine growth restriction. This study investigates whether the association is mediated through bacterial spread from periapical lesions to placenta (direct pathway) or systemic inflammatory reaction (indirect pathway).

    Materials And Methods: We compared birth outcomes in Malawian mothers with and without periapical infection. Read More

    [Nosocomial urinary tract and surgical site infection rates in the Maternity Ward at the General Referral Hospital in Katuba, Lubumbashi, Democratic Republic of the Congo].
    Pan Afr Med J 2017 21;28:57. Epub 2017 Sep 21.
    Ecole de Santé Publique, Université de Lubumbashi, République Démocratique du Congo.
    Introduction: In Intertropical Africa hospitalized patients are exposed to a risk of nosocomial infections. The dearth of published data on this subject limits the descriptive analysis of the situation. This study aimed to determine the incidence, the germs responsible for these infections and the risk factors of nosocomial infections in the Maternity Ward at the General Referral Hospital in Katuba, Lubumbashi, Democratic Republic of the Congo. Read More

    Assessing stakeholder perceptions of the acceptability and feasibility of national scale-up for a dual HIV/syphilis rapid diagnostic test in Malawi.
    Sex Transm Infect 2017 12;93(S4):S59-S64
    Division of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
    Objectives: The WHO recommends pregnant women receive both HIV and syphilis testing at their first antenatal care visit, as untreated maternal infections can lead to severe, adverse pregnancy outcomes. One strategy for increasing testing for both HIV and syphilis is the use of point-of-care (rapid) diagnostic tests that are simple, proven effective and inexpensive. In Malawi, pregnant women routinely receive HIV testing, but only 10% are tested for syphilis at their first antenatal care visit. Read More

    Bacterial, fungal, parasitological and pathological analyses of abortions in small ruminants from 2012-2016.
    Schweiz Arch Tierheilkd 2017 Dec;159(12):647-656
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern.
    Introduction: Abortion in small ruminants presents a clinical and economic problem with legal implications regarding animal health and zoonotic risk by some of the abortive pathogens. Several bacteria, fungi and parasites can cause abortion, but cost-orientated routine diagnostics only cover the most relevant epizootic agents. To cover a broad-range of common as well as underdiagnosed abortifacients, we studied 41 ovine and 36 caprine abortions by Stamp's modification of the Ziehl-Neelsen stain, culture for classical and opportunistic abortive agents, real-time PCR for C. Read More

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