29,205 results match your criteria Bacterial Infections and Pregnancy


Isolation and characterization of Listeria monocytogenes among women attending Jimma University medical center, Southwest Ethiopia.

BMC Infect Dis 2021 Jun 12;21(1):564. Epub 2021 Jun 12.

School of Medical Laboratory Sciences, Jimma University, Jimma, Ethiopia.

Background: Listeria monocytogenes (LM) has come to be a major public health issue of at-risk groups, causing high morbidity and mortality. Despite this data, studies are very limited in developing countries like Ethiopia. Thus, we aimed to isolate and characterize LM in terms of antibiogram and biofilm formation among pregnant women with fever, women with a history of spontaneous abortion, women with a history of fetal loss, and women with preterm delivery at Jimma University Medical Center (JUMC), southwest Ethiopia. Read More

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State-level trends in sudden unexpected infant death and immunization in the United States: an ecological study.

BMC Pediatr 2021 06 11;21(1):274. Epub 2021 Jun 11.

Institute for Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

Background: Sudden unexpected infant death (SUID) continues to be a major contributor to infant mortality in the United States. The objective was to analyze time trends in SUID and their association with immunization coverage.

Methods: The number of deaths and live births per year and per state (1992-2015) was obtained from the Centers for Disease Control and Prevention (CDC). Read More

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Vaccination in Pregnancy.

Dtsch Arztebl Int 2021 Apr;118(15):262-268

Gynecologist's office, Munich; Member of STIKOGynecologist's office, MunichDepartment of Pediatrics, University Hospital WürzburgInstitute of Virology, Ulm University Hospital, Ulm; Member of STIKOWorking Group Vaccination in Pregnancy, German Professional Association of Gynecologists, Munich.

Background: Vaccination during pregnancy can protect both the expecting mother and the unborn and newborn child from infectious diseases.

Methods: This review is based on publications retrieved by a selective literature search on the immunological particularities of infectious diseases affecting pregnant women, unborn children, and neonates, with particular attention to the guidelines of the German Standing Committee on Vaccinations (Ständige Impfkommission, STIKO) and the pertinent guidelines.

Results: Vaccination during pregnancy protects the expecting mother from a severe course of a number of different infectious diseases. Read More

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Paired Testing of Sexually Transmitted Infections With Urine Pregnancy Tests in Incarcerated Women.

Sex Transm Dis 2021 08;48(8S):S20-S25

Parkland Health and Hospital Systems, Correctional Health.

Background: In correctional facilities, sexually transmitted infections (STIs) are common, are often asymptomatic, and may lead to adverse outcomes such as infertility and increased HIV acquisition. In January 2020, testing for Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) was paired with routine urine pregnancy tests among women entering a large county jail to increase testing and detection of STIs.

Methods: The results of all GC/CT urine tests in the Dallas County Jail were collected from October 2019 to February 2020. Read More

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Diagnostic Performance of Various Methodologies for Group B S Screening in Pregnant Woman in China.

Front Cell Infect Microbiol 2021 24;11:651968. Epub 2021 May 24.

Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Maternal vaginal/rectal colonization of group B streptococcus (GBS) is a main risk for neonatal invasive infection. Efficient determination of GBS colonization in pregnant women is crucial. This study aimed to investigate the prevalence of GBS carriage and evaluate the diagnostic performance of six methodologies for GBS screening conducted in China, including blood agar plate, liquid chromogenic medium, and loop-mediated isothermal amplification (LAMP) without pre-enrichment, chromogenic agar plate with pre-enrichment, and GBS antigen detection without and with pre-enrichment in comparison with the standard reference method (Lim broth-enriched subculture with plating on 5% sheep blood agar). Read More

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Tuberculosis in pregnancy.

J Med Life 2021 Mar-Apr;14(2):165-169

Department of Obstetrics and Gynecology, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania.

Tuberculosis (TB) in pregnancy is not only a matter of the past; it is also a current problem. These days, TB appears through mass migration and tourism in countries where it was believed that this condition is eradicated. Adequate knowledge about the medical history of patients, risk factors, diagnosis and treatment of tuberculosis should be part of the armamentarium of each physician involved in clinical practice. Read More

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Methodologic approaches in studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women: A scoping review.

Vaccine 2021 06 2;39(29):3814-3824. Epub 2021 Jun 2.

US Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, Maryland, USA.

Objective: This scoping review mapped studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women.

Introduction: In the US, two vaccines are recommended for all pregnant women to prevent illness in the infant: inactivated influenza vaccine (recommended since 2004), and the combined tetanus-diphtheria-acellular pertussis (Tdap) vaccine (recommended since 2013). This scoping review maps the studies conducted to date that address questions about pediatric safety and effectiveness of vaccines administered during pregnancy and provides a knowledge base for evaluating the use of RWD to study this issue. Read More

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Factors influencing acceptance of vaccination during pregnancy in The Gambia and Senegal.

Vaccine 2021 06 1;39(29):3926-3934. Epub 2021 Jun 1.

Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, Gambia; The Vaccine Centre, Faculty of Infectious and Tropical Diseases, Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom. Electronic address:

Background: Vaccination during pregnancy can protect pregnant women and their babies from infectious diseases. Tetanus vaccine, also known as tetanus toxoid, is the only vaccine given to pregnant women in The Gambia and Senegal, where it is given by antenatal care providers as part of the Expanded Programme on Immunization. A qualitative study was undertaken to explore factors influencing acceptance of vaccination during pregnancy in The Gambia and Senegal. Read More

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Staphylococcus saprophyticus and Escherichia coli: Tracking from sperm fertility potential to assisted reproductive outcomes.

Clin Exp Reprod Med 2021 Jun 26;48(2):142-149. Epub 2021 May 26.

Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran.

Objective: Bacteriospermia and urogenital infections are common problems in male infertility. This study aimed to evaluate the effects of bacteriospermia on sperm parameters and clinical outcomes in semen samples infected with two common bacteria (Staphylococcus saprophyticus and Escherichia coli) in northern Iran.

Methods: Microbiological tests were performed to isolate and identify organisms from 435 semen samples from infertile couples. Read More

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Bacterial vaginosis in pregnancy: prevalence and outcomes in a tertiary care hospital.

Afr J Reprod Health 2021 Feb;25(1):49-55

Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.

Bacterial Vaginosis (BV) has recently emerged as a global health issue especially in pregnant women because of its adverse outcomes. Various studies have shown the impact of BV on both mother and baby as well as overall reproductive health of women. The study intended to assess the prevalence of BV in pregnant women visiting our hospital and estimate the risk of associated complications. Read More

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February 2021

Serosurvey and Risk Factors Associated with Infection in High Risk Occupations from District Lahore and Kasur of Punjab, Pakistan.

Pathogens 2021 May 18;10(5). Epub 2021 May 18.

Institute of Bacterial Infections and Zoonoses, Friedrich-Loeffler-Institut, Naumburger Str. 96a, 07743 Jena, Germany.

Brucellosis is a neglected zoonotic disease, and occupations with a high risk of infection exist. Limited information is available on brucellosis for these employees at high risk in Pakistan. A total of 459 persons with high-risk occupations, i. Read More

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From Infection to Pregnancy Complications: Key Role of the Immune Response of Placental Cells.

Pathogens 2021 May 19;10(5). Epub 2021 May 19.

Aix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.

The infection of pregnant animals and women by , an intracellular bacterium, compromises both maternal health and foetal development. The placenta is targeted by as demonstrated by bacteriological and histological evidence. It now appears that placental strains of   are highly virulent compared to reference strains and that placental injury involves different types of placental cells. Read More

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A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders.

J Transl Med 2021 05 31;19(1):230. Epub 2021 May 31.

iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Background: Infections are a major disease burden worldwide. While they are caused by external pathogens, host genetics also plays a part in susceptibility to infections. Past studies have reported diverse associations between human leukocyte antigen (HLA) alleles and infections, but many were limited by small sample sizes and/or focused on only one infection. Read More

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Disseminated nontuberculous mycobacteriosis and fungemia after second delivery in a patient with MonoMAC syndrome/GATA2 mutation: a case report.

BMC Infect Dis 2021 May 29;21(1):502. Epub 2021 May 29.

Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.

Background: Heterozygous mutations in the transcription factor GATA2 result in a wide spectrum of clinical phenotypes, including monocytopenia and Mycobacterium avium complex (MAC) infection (MonoMAC) syndrome. Patients with MonoMAC syndrome typically are infected by disseminated nontuberculous mycobacteria, fungi, and human papillomavirus, exhibit pulmonary alveolar proteinosis during late adolescence or early adulthood, and manifest with decreased content of dendritic cells (DCs), monocytes, and B and natural killer (NK) cells.

Case Presentation: A 39-year-old woman was diagnosed with MonoMAC syndrome postmortem. Read More

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A one-year descriptive epidemiology of zoonotic abortifacient pathogen bacteria in farm animals in Turkey.

Comp Immunol Microbiol Infect Dis 2021 Aug 15;77:101665. Epub 2021 May 15.

Selcuk University, Department of Microbiology, Faculty of Veterinary Medicine, Konya, Turkey. Electronic address:

This study aimed to investigate the epidemiology of 10 suspicious pathogenic bacteria in 250 stomach contents of aborted calf, lamb, and goat foetuses in 2019. The 155 positive samples obtained from PCR consisted of 53 (58.88 %) bacteria from 90 lamb samples, 10 (43. Read More

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Gut and vaginal microbiomes on steroids: implications for women's health.

Trends Endocrinol Metab 2021 08 25;32(8):554-565. Epub 2021 May 25.

Neuroscience Department, Wellesley College, Wellesley, MA 02481, USA. Electronic address:

This review discusses the interactions of steroids with the gut and vaginal microbiomes within each life phase of adult women and the implications for women's health. Each phase of a woman's life is characterized by distinct hormonal states which drive overall physiology of both host and commensal microbes. These host-microbiome interactions underlie disease pathology in disorders that affect women across their lifetime, including bacterial vaginosis, gestational diabetes, polycystic ovary syndrome (PCOS), anxiety, depression, and obesity. Read More

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Safety of vaccines used for routine immunization in the United States: An updated systematic review and meta-analysis.

Vaccine 2021 06 25;39(28):3696-3716. Epub 2021 May 25.

RAND Corporation, 1776 Main Street, Santa Monica, CA 90401, United States; Southern California Evidence Review Center, University of Southern California, Keck School of Medicine, 2001 N Soto Street, Los Angeles, CA 90033, United States.

Background: Understanding the safety of vaccines is critical to inform decisions about vaccination. Our objective was to conduct a systematic review of the safety of vaccines recommended for children, adults, and pregnant women in the United States.

Methods: We searched the literature in November 2020 to update a 2014 Agency for Healthcare Research and Quality review by integrating newly available data. Read More

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Prevalence of group B streptococcus colonization in pregnant women in Jiangsu, East China.

BMC Infect Dis 2021 May 27;21(1):492. Epub 2021 May 27.

Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, 211102, China.

Background: Group B streptococcus (GBS) is the leading cause of early-onset neonatal sepsis. However, GBS was infrequently reported in the developing world in contrast to western countries. This study assessed the prevalence of GBS colonization among pregnant women in Jiangsu, East China, and revealed the difference of GBS infection between culture and PCR. Read More

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Trend of Bacterial Uropathogens and Their Susceptibility Pattern: Study of Single Academic High-Volume Center in Italy (2015-2019).

Int J Microbiol 2021 21;2021:5541706. Epub 2021 Apr 21.

Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi 84081, SA, Italy.

Urinary tract infections (UTIs) are a very widespread infection that can occur in disparate age range, in both sexes and in pregnancy/menopause state. Treatment of UTIs is difficult due to the emergence of antibiotic-resistant bacterial strains. The present study shows five years of data collected on patients admitted at the University Hospital "San Giovann di Dio e Ruggi d'Aragona" in Salerno, Italy. Read More

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Isolation of Brucella melitensis biovar 1 from human milk confirms breastfeeding as a possible route for infant infection.

Microb Pathog 2021 Aug 21;157:104958. Epub 2021 May 21.

Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.

Brucellosis during pregnancy is associated with major concerns for mothers but, it is still not clear whether the infection could be transmitted through breastfeeding to newborns. This study aimed at evaluating the shedding of Brucella melitensis through human milk. We describe phenotypic and genotypic characterization of Brucella isolate from human milk. Read More

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Chlamydia, gonorrhea, and incident HIV infection during pregnancy predict preterm birth despite treatment.

J Infect Dis 2021 May 23. Epub 2021 May 23.

Department of Pediatrics, University of Washington, Seattle, WA, USA.

Background: Identifying predictors of preterm birth (PTB) in high burden regions is important as PTB is the leading cause of global child mortality.

Methods: This analysis was nested in a longitudinal study of peripartum HIV incidence in Kenya. HIV-seronegative women enrolled in pregnancy were screened with nucleic acid amplification tests (chlamydia and gonorrhea), RPR (syphilis), wet mount microscopy (Trichomonas and yeast), and Gram stain (bacterial vaginosis); sexually transmitted infection (STI) treatment was provided. Read More

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Prenatal infection and schizophrenia: A decade of further progress.

Schizophr Res 2021 May 17. Epub 2021 May 17.

Department of Psychiatry, New York State Psychiatric Institute, Columbia University Irving Medical Center, New York, NY, USA; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA. Electronic address:

Epidemiologic studies have provided evidence that prenatal exposure to maternal infection is associated with an increased risk of developing schizophrenia in the offspring. Research over the past decade has added further to our understanding of the role of prenatal infection in schizophrenia risk. These investigations include several well-powered designs, and like some earlier studies, measured maternal antibodies to specific infectious agents in stored serum samples and large registers to identify clinically diagnosed infections during pregnancy. Read More

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Factors associated with prematurity in reported cases of congenital syphilis.

Rev Saude Publica 2021 17;55:28. Epub 2021 May 17.

Universidade Federal do Espírito Santo. Departamento de Medicina Social. Vitoria, ES, Brasil.

Objective: To analyze the factors associated with prematurity in reported cases of congenital syphilis in the city of Fortaleza, Ceará, Brazil.

Methods: Cross-sectional study conducted in ten public maternity hospitals in Fortaleza, Ceará, Brazil. A total of 478 reported cases of congenital syphilis were included in 2015, and data were collected from notification forms, from mothers' and babies' medical records and from prenatal cards. Read More

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Brazilian Protocol for Sexually Transmitted Infections 2020: acquired syphilis.

Rev Soc Bras Med Trop 2021 17;54(suppl 1):e2020616. Epub 2021 May 17.

Ministério da Saúde, Secretaria de Vigilância em Saúde, Brasilia, DF, Brasil.

The Clinical Protocol and Therapeutic Guidelines for Comprehensive Care of People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020, includes updates concerning acquired syphilis. The document comprises rapid test use, safety and efficacy of benzathine benzylpenicillin, case follow-up, neurosyphilis clinical and laboratory management, approaching sex partners, assistance and monitoring of diagnosed pregnant women, and syphilis and HIV co-infection specificities, as well as a case notification summary. Health managers and professionals must be continuously trained so as to integrate care and surveillance, to strengthen actions for efficient control of syphilis, to broaden the search for sex partners, and to expand access of most vulnerable populations to health services. Read More

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Brazilian Protocol for Sexually Transmitted infections, 2020: pelvic inflammatory disease.

Rev Soc Bras Med Trop 2021 17;54(suppl 1):e2020602. Epub 2021 May 17.

Ministério da Saúde, Secretaria de Vigilância em Saúde, Brasilia, DF, Brasil.

Pelvic Inflammatory Disease is a topic included in the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020. Pelvic inflammatory disease is an upper female genital tract acute infection due to canalicular spread of endogenous cervicovaginal microorganisms and especially the sexually transmitted microorganisms. Standing out among the etiological agents involved are Chlamydia trachomatis and Neisseria gonorrhoeae. Read More

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Brazilian Protocol for Sexually Transmitted Infections, 2020: congenital syphilis and child exposed to syphilis.

Rev Soc Bras Med Trop 2021 17;54(suppl 1):e2020597. Epub 2021 May 17.

Universidade de Pernambuco, Departamento Materno-Infantil, Recife, PE, Brazil.

The topics of congenital syphilis and children exposed to syphilis compose the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020. Such document was elaborated based on scientific evidence and validated in discussions with specialists. This article provides guidelines for syphilis in pregnant women and congenital syphilis clinical management, emphasizing the vertical transmission of Treponema pallidum prevention. Read More

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Brazilian Protocol for Sexually Transmitted Infections 2020: epidemiological surveillance.

Rev Soc Bras Med Trop 2021 17;54(suppl 1):e2020549. Epub 2021 May 17.

Secretaria de Estado da Saúde de São Paulo, Centro de Referência e Treinamento de Doenças Sexualmente Transmissíveis e Aids, São Paulo, SP, Brazil.

This article summarizes the chapter on epidemiological surveillance of sexually transmitted infections (STI) that comprises the 2020 Clinical Protocol and Therapeutic Guidelines (PCDT) for Comprehensive Care for People with STI, published by the Health Surveillance Department of the Brazilian Ministry of Health. It presents some reflections on the new case definitions for surveillance of acquired syphilis, syphilis in pregnant women, and congenital syphilis. The 2020 PCDT-IST was elaborated grounded on scientific evidence and validated in discussions with specialists. Read More

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Spectrum of uropathogens and their susceptibility to antimicrobials in pregnant women: a retrospective analysis of 5-year hospital data.

J Int Med Res 2021 May;49(5):3000605211006540

Department of Internal Medicine, School of Medicine, The University of Jordan, Amman, Jordan.

Objective: Urinary tract infections (UTI) are common during pregnancy. Identification of antimicrobial susceptibility patterns of microorganisms in pregnant women is important to select the most appropriate antimicrobial. We assessed common uropathogens in pregnant women with UTI and antimicrobial susceptibility, to guide empirical antibiotic selection. Read More

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Emerging progress on diagnosis and treatment of female genital tuberculosis.

J Int Med Res 2021 May;49(5):3000605211014999

Department of Respiratory Medicine, Jingzhou Chest Hospital, Jingzhou, Hubei, China.

Female genital tuberculosis (FGTB) is an infection caused by and usually occurs secondary to pulmonary tuberculosis (TB) through the blood circulation, lymph circulation, or direct spreading from abdominal TB. FGTB is an uncommon type of TB that can destroy genital organs, and lead to menstrual disorders and infertility. The diagnosis of FGTB is often made by detection of acid-fast bacilli under microscopy, culture with endometrial biopsy, or histopathological examination of epithelioid granuloma on a biopsy. Read More

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