4,642 results match your criteria Babesiosis


A 4-Yr Survey of the Range of Ticks and Tick-Borne Pathogens in the Lehigh Valley Region of Eastern Pennsylvania.

J Med Entomol 2019 Apr 23. Epub 2019 Apr 23.

Suppan LLC, 3870 Kreidersville Road, Northampton, PA.

Questing ticks were surveyed by dragging in forested habitats within the Lehigh Valley region of eastern Pennsylvania for four consecutive summers (2015-2018). A high level of inter-annual variation was found in the density of blacklegged tick nymphs, Ixodes scapularis Say, with a high density of host-seeking nymphs (DON) in summer 2015 and 2017 and a relatively low DON in summer 2016 and 2018. Very few American dog ticks (Dermacentor variabilis Say) and Ixodes cookei Packard were collected. Read More

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http://dx.doi.org/10.1093/jme/tjz043DOI Listing

Pharmacokinetics of imidocarb dipropionate in white-tailed deer (Odocoileus virginianus) after single intramuscular administration.

J Vet Pharmacol Ther 2019 Apr 1. Epub 2019 Apr 1.

Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

This study was designed to investigate the pharmacokinetics of imidocarb, a carbanilide derivative, in white-tailed deer (Odocoileus virginianus). The pharmacokinetic properties of a single intramuscular (IM) dose of imidocarb were determined in 10 deer. A single IM injection of 3. Read More

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http://dx.doi.org/10.1111/jvp.12760DOI Listing
April 2019
1 Read

Transfusion-Transmitted Infections Reported to the National Healthcare Safety Network Hemovigilance Module.

Transfus Med Rev 2019 Jan 25. Epub 2019 Jan 25.

Office of Blood, Organ, and Other Tissue Safety, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention.

Transfusion-transmitted infections (TTIs) can be severe and result in death. Transfusion-transmitted viral pathogen transmission has been substantially reduced, whereas sepsis due to bacterial contamination of platelets and transfusion-transmitted babesiosis may occur more frequently. Quantifying the burden of TTI is important to develop targeted interventions. Read More

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http://dx.doi.org/10.1016/j.tmrv.2019.01.001DOI Listing
January 2019
1 Read

Thromboelastographic platelet mapping in dogs with complicated Babesia rossi infection.

Vet Clin Pathol 2019 Mar;48(1):11-18

Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.

Background: Dogs with Babesia rossi infection display a normocoagulable thromboelastogram, despite being markedly thrombocytopenic, which is purportedly due to large-scale platelet activation. Thromboelastographic platelet mapping (TEG-PM) evaluates individual contributions of thrombin, fibrinogen, and platelets to clot formation, and may elucidate some of the pathomechanisms of thrombocytopenia-associated hemostatic alterations.

Objective: This study investigated potential differences in TEG-PM variables in dogs with complicated B rossi infection compared with healthy controls, and whether these variables correlated with platelet activation indices. Read More

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http://dx.doi.org/10.1111/vcp.12689DOI Listing
March 2019
1 Read

A review on the occurrence of companion vector-borne diseases in pet animals in Latin America.

Parasit Vectors 2019 Mar 28;12(1):145. Epub 2019 Mar 28.

Institute of Parasitology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.

Companion vector-borne diseases (CVBDs) are an important threat for pet life, but may also have an impact on human health, due to their often zoonotic character. The importance and awareness of CVBDs continuously increased during the last years. However, information on their occurrence is often limited in several parts of the world, which are often especially affected. Read More

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http://dx.doi.org/10.1186/s13071-019-3407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438007PMC
March 2019
1 Read

Establishment of Babesia vulpes n. sp. (Apicomplexa: Babesiidae), a piroplasmid species pathogenic for domestic dogs.

Parasit Vectors 2019 Mar 26;12(1):129. Epub 2019 Mar 26.

Instituto de Patobiología Veterinaria, (CICVyA), Instituto Nacional de Tecnología Agropecuaria (INTA), 1686, Hurlingham, Argentina.

Background: Canine babesiosis is a severe disease caused by several Babesia spp. A number of names have been proposed for the canine-infecting piroplasmid pathogen initially named Theileria annae Zahler, Rinder, Schein & Gothe, 2000. It was shown to be a member of the Babesia (sensu lato) group infecting carnivores and is also closely related to the Babesia microti group. Read More

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http://dx.doi.org/10.1186/s13071-019-3385-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434798PMC

A novel Babesia sp. associated with clinical signs of babesiosis in domestic cats in South Africa.

Parasit Vectors 2019 Mar 26;12(1):138. Epub 2019 Mar 26.

Vectors and Vector-borne Diseases Research Programme, Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.

Background: Feline babesiosis, sporadically reported from various countries, is of major clinical significance in South Africa, particularly in certain coastal areas. Babesia felis, B. leo, B. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-019-3395-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434806PMC
March 2019
2 Reads

The role of healthy dog carriers of Babesia microti-like piroplasms.

Parasit Vectors 2019 Mar 26;12(1):127. Epub 2019 Mar 26.

Department of Animal Health, Veterinary Faculty, Universidad Complutense de Madrid, Madrid, Spain.

Background: While in Europe Babesia canis has been traditionally held responsible for canine piroplasmosis, Babesia microti-like piroplasm (Bml) infection is being ever more observed in dogs, with the first clinical cases reported in northwestern Spain. This study examines the epidemiological role of healthy dogs living in endemic areas of Bml infection in Spain. The data obtained were used to describe the clinical status and map the geographical distribution of Bml infection in healthy dogs in northwestern Spain. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-019-3371-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434893PMC
March 2019
3 Reads

Development of a SNP barcode to genotype Babesia microti infections.

PLoS Negl Trop Dis 2019 03 25;13(3):e0007194. Epub 2019 Mar 25.

Broad Institute, Cambridge, Massachusetts, United States of America.

Babesia microti is tick-borne disease that is an emerging threat to public health due to increasing prevalence and expanding geographic range. Detection and constant surveillance of babesiosis is imperative for predicting pathogen expansion. Leveraging our whole genome sequence (WGS) analyses of B. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448979PMC

Babesiosis Masquerading as Evans Syndrome.

Am J Med 2019 Mar 20. Epub 2019 Mar 20.

Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.amjmed.2019.02.041DOI Listing
March 2019
1 Read

Morphological and physiological, biological and epidemiological features of acariana of the genus ixodes (latreille, 1795) - human ectoparasites in biogeocenoses of ternopil region.

Wiad Lek 2019 ;72(2):224-228

State Higher Educational Establishment Ivan Horbachevsky Ternopil State Medical University of Ministry of Public Health of Ukraine, Ternopil, Ukraine.

Objective: Introduction: Ixodine are an integral part of many biotopes, in particular rarefied deciduous and mixed forests, gardens, parks, squares, semi-steppe and steppe areas, etc. Over the past decade, the role of ticks has increased in the transfer of pathogens of many diseases of animals and humans. In particular, these are tick borelliosis, anaplasmosis, erlichiosis, babesiosis, and etc. Read More

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January 2019

A study on the long-term efficacy of Seresto® collars in preventing Babesia canis (Piana & Galli-Valerio, 1895) transmission to dogs by infected Dermacentor reticulatus (Fabricius, 1794) ticks.

Parasit Vectors 2019 Mar 22;12(1):139. Epub 2019 Mar 22.

Bayer Animal Health GmbH, Monheim, Germany.

Background: An imidacloprid/flumethrin collar (Seresto®) was previously shown to prevent infection with Babesia canis, transmitted by Dermacentor reticulatus, in dogs for up to 1 month after application. The present study evaluated the prevention of transmission throughout the claimed efficacy period of 8 months.

Methods: Eight animals each were randomly included in groups 1 (negative control) and 2 (Seresto® collar), respectively. Read More

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http://dx.doi.org/10.1186/s13071-019-3393-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431040PMC
March 2019
3.430 Impact Factor

Presence of and Sensu Stricto in a Tick and Dual Parasitism of and on a Bird in Canada.

Healthcare (Basel) 2019 Mar 20;7(1). Epub 2019 Mar 20.

Department of Biology, Georgia Southern University, Statesboro, GA 30458, USA.

Wild birds transport ticks into Canada that harbor a diversity of zoonotic pathogens. However, medical practitioners often question how these zoonotic pathogens are present in their locality. In this study, we provide the first report of an tick cofeeding with a blacklegged tick, , which parasitized a Veery, -a neotropical songbird. Read More

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http://dx.doi.org/10.3390/healthcare7010046DOI Listing
March 2019
1 Read

Increasing Babesiosis in Southeastern Pennsylvania, 2008-2017.

Open Forum Infect Dis 2019 Mar 11;6(3):ofz066. Epub 2019 Feb 11.

Department of Medicine, Main Line Health System, Bryn Mawr, Pennsylvania.

Tick-borne illnesses are increasing but are often underreported. Few cases of babesiosis have been reported from Pennsylvania. Our 4-hospital system in southeastern Pennsylvania saw a rise in cases from 7 or fewer yearly in 2008-2014 to 26 cases in 2015. Read More

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http://dx.doi.org/10.1093/ofid/ofz066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419987PMC
March 2019
2 Reads

Molecular detection and genetic diversity of Babesia canis canis in pet dogs in Henan Province, China.

Parasitol Int 2019 Mar 15;71:37-40. Epub 2019 Mar 15.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu 730046, China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonosis, Yangzhou University, Yangzhou 225009, China. Electronic address:

Canine babesiosis is an important tick-borne disease caused by Babesia spp. A total of 130 blood samples were randomly collected from pet dogs in Zhengzhou city, Henan Province, China, and screened for the presence of piroplasms with nested PCR and gene sequencing targeting the 18S rRNA gene. On the basis of blast analysis of the 18S rRNA gene sequences, our results revealed that seven dogs (5. Read More

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http://dx.doi.org/10.1016/j.parint.2019.03.011DOI Listing

Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1.

Int J Gen Med 2019 18;12:101-119. Epub 2019 Feb 18.

Hudson Valley Healing Arts Center, Hyde Park, NY 12538, USA,

Purpose: We collected data from an online survey of 200 of our patients, which evaluated the efficacy of dapsone (diaminodiphenyl sulfone, ie, DDS) combined with other antibiotics and agents that disrupt biofilms for the treatment of chronic Lyme disease/post-treatment Lyme disease syndrome (PTLDS). We also collected aggregate data from direct retrospective chart review, including laboratory testing for Lyme, other infections, and associated tick-borne coinfections. This helped us to determine the frequency of exposure to other infections/coinfections among a cohort of chronically ill Lyme patients, evaluate the efficacy of newer "persister" drug regimens like DDS, and determine how other infections and tick-borne coinfections may be contributing to the burden of chronic illness leading to resistant symptomatology. Read More

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http://dx.doi.org/10.2147/IJGM.S193608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388746PMC
February 2019
2 Reads

Babesia odocoilei and zoonotic pathogens identified from Ixodes scapularis ticks in southern Ontario, Canada.

Ticks Tick Borne Dis 2019 04 27;10(3):670-676. Epub 2019 Feb 27.

Ontario Veterinary College, University of Guelph, 50 Stone Rd. E, Guelph, ON, N1G 2W1, Canada; Southeastern Cooperative Wildlife Disease Study, University of Georgia, Athens, GA, 30602, United States.

Cervid babesiosis, caused by the protozoan hemoparasite Babesia odocoilei and transmitted by the blacklegged tick Ixodes scapularis, is an emerging disease of Canadian cervids. This pathogen has not yet been described in humans. Data are lacking on the role of migratory birds in the adventitious spread of Ba. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2019.02.016DOI Listing
April 2019
1 Read

Cathepsin L-a novel cysteine protease from Haemaphysalis flava Neumann, 1897.

Parasitol Res 2019 Mar 2. Epub 2019 Mar 2.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine Huazhong Agricultural University, Wuhan, 430070, Hubei, China.

Ixodid ticks are ectoparasites responsible for the transmission of a large number of bacterial, viral, and protozoan pathogens to animals and humans. As long-term blood-pool feeders, the digestion of host blood is critical to their development as well as to the establishment of the sexual cycle of hemoparasites such as Babesia parasites, the agents of human and animal babesiosis. Previous studies have demonstrated that cysteine proteases are involved in blood digestion, embryogenesis, and pathogen transmission in other species of ticks, but their characteristics and functions are still unidentified in Haemaphysalis flava. Read More

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http://dx.doi.org/10.1007/s00436-019-06271-4DOI Listing
March 2019
2 Reads

Development of unstable resistance to diminazene aceturate in Babesia bovis.

Int J Parasitol Drugs Drug Resist 2019 Apr 13;9:87-92. Epub 2019 Feb 13.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan. Electronic address:

Diminazene aceturate (DA) is commonly used in the treatment of bovine babesiosis caused by Babesia bovis. In this study, we attempted to develop resistance in B. bovis in vitro to DA and clofazimine (CF, a novel antibabesial agent) using short- and long-term drug pressures. Read More

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http://dx.doi.org/10.1016/j.ijpddr.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382846PMC
April 2019
2.514 Impact Factor

Human Babesiosis in China: a systematic review.

Parasitol Res 2019 Apr 15;118(4):1103-1112. Epub 2019 Feb 15.

Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, National Demonstration Center for Experimental Basic Medical Science Education, Xuzhou Medical University, 221004, Xuzhou, People's Republic of China.

Human babesiosis, a worldwide emerging tick-borne disease, is caused by the intraerythrocytic apicomplexan parasite, babesia. In recent years, the number of infected patients globally has continued to rise, and thus human babesiosis poses a significant public health threat. Therefore, stronger initiatives should be undertaken to prevent further spread and development of this disease. Read More

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http://dx.doi.org/10.1007/s00436-019-06250-9DOI Listing
April 2019
7 Reads

Human Tick-Borne Diseases in Australia.

Front Cell Infect Microbiol 2019 28;9. Epub 2019 Jan 28.

Neuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.

There are 17 human-biting ticks known in Australia. The bites of , and can cause paralysis, inflammation, and severe local and systemic reactions in humans, respectively. Six ticks, including , and may transmit , or subsp. Read More

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http://dx.doi.org/10.3389/fcimb.2019.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360175PMC
January 2019
7 Reads

Splenic infarction as a rare presentation of severe babesiosis.

IDCases 2019 23;15:e00491. Epub 2019 Jan 23.

Department of Medicine, St. Vincent's Medical Center, Bridgeport, CT; The Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT, United States.

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http://dx.doi.org/10.1016/j.idcr.2019.e00491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355617PMC
January 2019

Paralogs vs. genotypes? Variability of Babesia canis assessed by 18S rDNA and two mitochondrial markers.

Vet Parasitol 2019 Feb 18;266:103-110. Epub 2019 Jan 18.

CEITEC-VFU, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, 612 42, Brno, Czech Republic; Department of Pathological Morphology and Parasitology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, 612 42, Brno, Czech Republic; Biology Centre, Institute of Parasitology, Czech Academy of Sciences, Branišovská 31, 370 05, České Budějovice, Czech Republic.

Canine babesiosis caused by Babesia canis sensu stricto became an emerging disease of dogs across Europe calling for attention also in countries where it was an only rare imported disease. An easy accessibility of molecular methods and the growing amount of sequencing data led to the description of intraspecific variability in 18S rDNA sequences designated as "genotypes". Using material from a homogenous cohort of dogs with microscopically confirmed canine babesiosis caused by B. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.12.017DOI Listing
February 2019
3 Reads

Transgenic Babesia bovis lacking 6-Cys sexual-stage genes as the foundation for non-transmissible live vaccines against bovine babesiosis.

Ticks Tick Borne Dis 2019 04 25;10(3):722-728. Epub 2019 Jan 25.

Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA, USA; Animal Disease Research Unit, United States Department of Agricultural - Agricultural Research Service, Pullman, WA, USA. Electronic address:

Babesia bovis, a tick-borne apicomplexan parasite responsible for bovine babesiosis has a complex life cycle including sexual development in its Rhipicephalus microplus vector. Understanding the molecular mechanisms involved in sexual development is essential for developing future-generation transmission blocking vaccines (TBVs) and/or non-transmissible attenuated live vaccines. The widely conserved members of the 6-Cys gene family likely play roles in the development of sexual stages of B. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1877959X183022
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http://dx.doi.org/10.1016/j.ttbdis.2019.01.006DOI Listing
April 2019
9 Reads

The role of particular ticks developmental stages in the circulation of tick-borne pathogens in Central Europe. 6. Babesia.

Ann Parasitol 2018;64(4):265-284

Department of Biochemistry and Molecular Biology, University of Natural Sciences and Humanities, ul. Prusa 12, 08-110 Siedlce, Poland

In the Central European conditions, three species of Babesia have epidemiological significance as human pathogens – Babesia divergens, B. microti and B. venatorum. Read More

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Congenital Babesiosis From Maternal Exposure: A Case Report.

J Emerg Med 2019 Apr 29;56(4):e39-e41. Epub 2019 Jan 29.

Division of Pediatric Emergency Medicine, NYU Langone Medical Center, New York, New York.

Background: Babesiosis is a disease caused by parasites that infect red blood cells; in infants it can be acquired from tick bites, blood transfusions, or congenitally via vertical transmission. It can present with thrombocytopenia, fevers, and parasitemia.

Case Report: A case of vertically transmitted babesiosis in an infant is described. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.12.044DOI Listing
April 2019
1 Read

High co-infection rates of Babesia bovis, Babesia bigemina, and Anaplasma marginale in water buffalo in Western Cuba.

Parasitol Res 2019 Mar 28;118(3):955-967. Epub 2019 Jan 28.

Centro Nacional de Sanidad Agropecuaria, Apartado Postal 10, Carretera de Jamaica y Autopista Nacional, San José de Las Lajas, CP 32700, Mayabeque, Cuba.

Water buffalo is important livestock in several countries in the Latin American and Caribbean regions. This buffalo species can be infected by tick-borne hemoparasites and remains a carrier of these pathogens which represent a risk of infection for more susceptible species like cattle. Therefore, studies on the epidemiology of tick-borne hemoparasites in buffaloes are required. Read More

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http://dx.doi.org/10.1007/s00436-018-06194-6DOI Listing
March 2019
2 Reads

Human babesiosis.

Authors:
Peter J Krause

Int J Parasitol 2019 Feb 26;49(2):165-174. Epub 2019 Jan 26.

Yale School of Public Health and Yale School of Medicine, New Haven, CT, USA. Electronic address:

Babesiosis is a worldwide emerging tick-borne disease that is increasing in frequency and geographic range. It imposes a significant health burden, especially on those who are immunocompromised and those who acquire the infection through blood transfusion. Death from babesiosis occurs in up to 20 percent of these groups. Read More

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http://dx.doi.org/10.1016/j.ijpara.2018.11.007DOI Listing
February 2019

Unravelling the cellular and molecular pathogenesis of bovine babesiosis: is the sky the limit?

Int J Parasitol 2019 Feb 26;49(2):183-197. Epub 2019 Jan 26.

Department of Microbiology, Biomedicine Discovery Institute, Monash University, Victoria 3800, Australia. Electronic address:

The global impact of bovine babesiosis caused by the tick-borne apicomplexan parasites Babesia bovis, Babesia bigemina and Babesia divergens is vastly underappreciated. These parasites invade and multiply asexually in bovine red blood cells (RBCs), undergo sexual reproduction in their tick vectors (Rhipicephalus spp. for B. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00207519183030
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http://dx.doi.org/10.1016/j.ijpara.2018.11.002DOI Listing
February 2019
8 Reads

Vaccination against babesiosis using recombinant GPI-anchored proteins.

Int J Parasitol 2019 Feb 24;49(2):175-181. Epub 2019 Jan 24.

Vaccination Anti-Parasitaire (VAP), University of Montpellier, France; Department of Veterinary Tropical Diseases, Veterinary Faculty, University of Pretoria, South Africa. Electronic address:

The increase in human babesiosis is of major concern to health authorities. In the USA, most of these cases are due to infections with Babesia microti, whereas in Europe B. divergens is the major cause of clinical disease in humans. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00207519193000
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http://dx.doi.org/10.1016/j.ijpara.2018.12.002DOI Listing
February 2019
20 Reads

Babesial infection in the Madagascan flying fox, Pteropus rufus É. Geoffroy, 1803.

Parasit Vectors 2019 Jan 23;12(1):51. Epub 2019 Jan 23.

Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.

Background: Babesiae are erythrocytic protozoans, which infect the red blood cells of vertebrate hosts to cause disease. Previous studies have described potentially pathogenic infections of Babesia vesperuginis in insectivorous bats in Europe, the Americas and Asia. To date, no babesial infections have been documented in the bats of Madagascar, or in any frugivorous bat species worldwide. Read More

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http://dx.doi.org/10.1186/s13071-019-3300-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343336PMC
January 2019

PCR detection of Ehrlichia ruminantium and Babesia bigemina in cattle from Kwara State, Nigeria: unexpected absence of infection.

Parasitol Res 2019 Mar 17;118(3):1025-1029. Epub 2019 Jan 17.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, UK.

Ticks and tick-borne diseases (TBDs) continue to pose an insidious and ever-present threat to livestock and livelihoods across the globe. Two of the most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in Nigeria. Read More

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http://dx.doi.org/10.1007/s00436-019-06204-1DOI Listing
March 2019
1 Read
2.327 Impact Factor

Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites.

Parasit Vectors 2019 Jan 16;12(1):37. Epub 2019 Jan 16.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, Japan.

Background: Developing new antibabesial drugs with a low toxic effect to the animal and with no resistance from Babesia parasites is in urgent demand. In this concern, the antimalarial, anticancer and antioxidant effect of thymoquinone (TQ), a phytochemical compound found in the plant Nigella sativa, has been reported. Therefore, in the present study, the antibabesial effect of this compound was evaluated on the growth of piroplasm parasites. Read More

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http://dx.doi.org/10.1186/s13071-019-3296-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335684PMC
January 2019
3 Reads
3.430 Impact Factor

Inhibitory effects of the phytohormone inhibitors fluridone and inabenfide against Babesia gibsoni in vitro.

Vet Parasitol 2019 Jan 7;265:19-23. Epub 2018 Dec 7.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan. Electronic address:

Pharmacological options to treat canine babesiosis caused by Babesia gibsoni, are limited. To address this challenge, screening for novel drug candidates and drug targets against B. gibsoni is urgently needed. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.11.018DOI Listing
January 2019
4 Reads

Two Imported Cases of Babesiosis with Complication or Co-Infection with Lyme Disease in Republic of Korea.

Korean J Parasitol 2018 Dec 31;56(6):609-613. Epub 2018 Dec 31.

Department of Internal Medicine, Inha University School of Medicine, Incheon 22212, Korea.

Babesiosis, caused by Babesia microti and B. divergens, is transmitted by Ixodid ticks. Symptoms of babesiosis vary from a mild flu-like illness to acute, severe, and sometimes fatal and fulminant disease. Read More

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http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2018.56
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http://dx.doi.org/10.3347/kjp.2018.56.6.609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327201PMC
December 2018
6 Reads

Age-Related Differential Stimulation of Immune Response by and During Acute Phase of Infection Affects Disease Severity.

Front Immunol 2018 7;9:2891. Epub 2018 Dec 7.

Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ, United States.

Lyme disease is the most prominent tick-borne disease with 300,000 cases estimated by CDC every year while ~2,000 cases of babesiosis occur per year in the United States. Simultaneous infection with and are now the most common tick-transmitted coinfections in the U.S. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02891
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http://dx.doi.org/10.3389/fimmu.2018.02891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300717PMC
December 2018
10 Reads

Babesiosis prevalence in malaria-endemic regions of Colombia.

J Vector Borne Dis 2018 Jul-Sep;55(3):222-229

Malaria Group, Faculty of Medicine, University of Antioquia, Medellín, Colombia.

Background & Objectives: : The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity of the disease symptoms with malaria specially in the regions where malaria is endemic. The aim of the present work was to study the frequency of Babesia infection in humans, bovines and ticks in a malaria endemic region of Colombia, and explore the possible relationship of infection with host and the environmental factors. Read More

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http://www.jvbd.org/text.asp?2018/55/3/222/249480
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http://dx.doi.org/10.4103/0972-9062.249480DOI Listing
February 2019
9 Reads

What is your diagnosis? A feline blood smear.

Vet Clin Pathol 2019 03 7;48(1):128-130. Epub 2019 Jan 7.

Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada.

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http://dx.doi.org/10.1111/vcp.12682DOI Listing

Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation.

Parasit Vectors 2019 Jan 5;12(1). Epub 2019 Jan 5.

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164, USA.

Background: Rhipicephalus microplus is an efficient biological vector of Babesia bovis, a causative agent of bovine babesiosis. Babesia bovis is passed transovarially to the next generation of ticks, which then transmit the parasite to naïve animals. Due to the importance of the R. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13071-018-3270-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321724PMC
January 2019
2 Reads

Development and validation of a multiplex, real-time PCR assay for Babesia rossi and Babesia vogeli.

Ticks Tick Borne Dis 2019 02 14;10(2):421-432. Epub 2018 Dec 14.

Vector and Vector-borne Diseases Programme, Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa. Electronic address:

Canine babesiosis is caused by tick-transmitted intraerythrocytic protozoan parasites occurring worldwide. In southern Africa, babesiosis is caused by Babesia rossi and B. vogeli and is one of the most common and important infectious diseases affecting dogs. Read More

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http://dx.doi.org/10.1016/j.ttbdis.2018.12.004DOI Listing
February 2019
2 Reads

Identification and molecular characterization of a novel Babesia orientalis thrombospondin-related anonymous protein (BoTRAP1).

Parasit Vectors 2018 Dec 27;11(1):667. Epub 2018 Dec 27.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.

Background: The thrombospondin-related anonymous protein (TRAP) family, a kind of transmembrane protein, is widely distributed with a conserved feature of structure in all apicomplexan parasites and plays a crucial role in the gliding motility and survival of parasites.

Methods: The Babesia orientalis TRAP1 gene (BoTRAP1) was truncated and cloned into a pET-42b expression vector and expressed as a GST-tag fusion protein with a TEV protease site. Rabbit anti-rBoTRAP1 antibody was produced and purified using a protein A chromatography column. Read More

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http://dx.doi.org/10.1186/s13071-018-3245-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307320PMC
December 2018
3 Reads

Molecular study of transovarial transmission of Babesia canis in the Dermacentor reticulatus tick.

Ann Agric Environ Med 2018 Dec 26;25(4):669-671. Epub 2018 Sep 26.

Faculty of Biology, University of Warsaw, Poland.

The Dermacentor reticulatus tick is a main vector of Babesia canis in Europe. The risk of canine babesiosis is unpredictable, due to significant differences in the prevalence of B. canis between ticks originating from closely situated regions. Read More

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http://dx.doi.org/10.26444/aaem/94673DOI Listing
December 2018

Babesiosis as a cause of acute respiratory distress syndrome: a series of eight cases.

Postgrad Med 2019 Mar 26;131(2):138-143. Epub 2018 Dec 26.

a Division of Pulmonary, Critical Care, and Sleep Medicine , Westchester Medical Center , Valhalla , NY , USA.

Objectives: The characteristics of patients with Acute Respiratory Distress Syndrome (ARDS) as a complication of Babesia microti infection have not been systematically described.

Methods: Adult patients admitted to the medical intensive care unit (MICU) of a tertiary care hospital in the Lower Hudson Valley of New York from 1/1/2008 to 8/1/2016 were evaluated for ARDS complicating babesiosis.

Results: Of 22 patients with babesiosis in the MICU, eight (36. Read More

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https://www.tandfonline.com/doi/full/10.1080/00325481.2019.1
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http://dx.doi.org/10.1080/00325481.2019.1558910DOI Listing
March 2019
21 Reads

Molecular characterization of South Indian field isolates of bovine Babesia spp. and Anaplasma spp.

Parasitol Res 2019 Feb 17;118(2):617-630. Epub 2018 Dec 17.

Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, Pookode, Wayanad, Kerala, 673 576, India.

Ticks and tick-borne diseases (TTBDs) are considered major causes of economic loss in the livestock sector which incur an annual control cost estimated at US$ 498.7 million in India. Among these diseases, babesiosis, theileriosis and anaplasmosis are listed among the top ten livestock diseases in India and cause significant mortality and morbidity among cattle. Read More

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http://dx.doi.org/10.1007/s00436-018-6172-4DOI Listing
February 2019
1 Read

International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies.

Vox Sang 2019 Jan 6;114(1):17-27. Epub 2018 Dec 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background And Objectives: Globally, blood safety interventions have been successful in mitigating risk of the major transfusion-transmitted (TT) viruses. However, strategies that address risk from parasites are comparatively limited. TT parasites are often regional in nature, posing unique challenges; we sought to understand their impact on blood safety. Read More

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http://dx.doi.org/10.1111/vox.12727DOI Listing
January 2019
6 Reads

Babesiosis-Associated Splenic Rupture: Case Series from a Hyperendemic Region.

Clin Infect Dis 2018 Dec 12. Epub 2018 Dec 12.

Department of Medicine, Rhode Island Hospital and Alpert Medical School of Brown University.

Background: Spontaneous splenic rupture is an increasingly reported complication of babesiosis and has been described as a severe complication.

Methods: We performed a retrospective chart review in a high prevalence area to identify seven cases of babesiosis-related splenic rupture between 2014 - 2016.

Results: Splenic rupture occurred in approximately 1% of babesiosis cases. Read More

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http://dx.doi.org/10.1093/cid/ciy1060DOI Listing
December 2018
2 Reads

Transplacental transmission of Theileria equi in mules: Should we worry?

Vet Parasitol 2018 Dec 26;264:39-41. Epub 2018 Oct 26.

College of Veterinary Medicine and Animal Science, University of São Paulo, Department of Internal Medicine, São Paulo, Brazil. Electronic address:

Equine piroplasmosis, disease globally responsible for significant economic losses, is caused by the transmission of the hemoprotozoa Theileria equi and Babesia caballi by ticks. Transplacental transmission has been reported previously in horses, which is not the case for mules´ foals. The present study investigated, by Real Time-PCR (RT-PCR), the presence of both Theileria equi and Babesia caballi in newborn mules before the ingestion of colostrum. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.10.017DOI Listing
December 2018
3 Reads

Endochin-Like Quinolones Exhibit Promising Efficacy Against and in Experimentally Infected Pregnant Mice.

Front Vet Sci 2018 19;5:285. Epub 2018 Nov 19.

Vetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.

We report on the efficacy of selected endochin-like quinolones (ELQs) against tachyzoites grown in human foreskin fibroblasts (HFF), and in a pregnant BALB/c mouse model. Fourteen ELQs were screened against transgenic tachyzoites expressing β-galactosidase (Nc-βgal). Drugs were added concomitantly to infection and the values for 50% proliferation inhibition (IC) were determined after 3 days. Read More

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http://dx.doi.org/10.3389/fvets.2018.00285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252379PMC
November 2018
3 Reads