5,430 results match your criteria Babesiosis

High Asymptomatic Cases of Babesiosis in Dogs and Comparison of Diagnostic Performance of Conventional PCR vs Blood Smears.

Acta Parasitol 2022 May 25. Epub 2022 May 25.

Department of Zoology, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka.

Purpose: Babesiosis is one of the most important globally extended and quickly spreading tick-borne infections of dogs. Diagnosis of babesiosis in Sri Lanka is based on clinical signs followed by thin blood smears which could be error-prone due to undetected early infections, absence of clinical signs or low parasitemia. The present study investigated the prevalence of babesiosis in dogs presented to the Veterinary Teaching Hospital (VTH) at the Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, for treatments, vaccinations, and regular check-ups, and compared the diagnosis methods of microscopy and molecular analysis. Read More

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Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada.

Emerg Infect Dis 2022 Jun;28(6):1292-1294

In July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections. Read More

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A 6-year retrospective report of livestock parasitic diseases in the Eastern Cape Province, South Africa.

Open Vet J 2022 Mar-Apr;12(2):204-211. Epub 2022 Mar 28.

Department of Livestock and Pasture Sciences, Faculty of Science and Agriculture, University of Fort Hare, P/Bag X1314, Alice 5700, South Africa.

Background: Parasites contribute significantly to the decline of livestock production and productivity and consequently hamper the availability of protein food resources.

Aim: This study aims to report the prevalence of parasitic diseases in the Eastern Cape Province (ECP), South Africa.

Method: Retrospective data of animal diseases in the ECP from 2013 to 2018 was obtained from the veterinary unit of the Department of Rural and Agrarian Reform database, decoded analyzed, and interpreted. Read More

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Prevalence of bovine Babesia spp., Anaplasma marginale, and their co-infections in Latin America: Systematic review-meta-analysis.

Ticks Tick Borne Dis 2022 May 14;13(4):101967. Epub 2022 May 14.

Curso de Pós-Graduação em Produção e Sanidade Animal (PPGPSA), Instituto Federal Catarinense (IFC), Campus Araquari, Santa Catarina 89245-000, Brazil. Electronic address:

Bovine parasitic sadness, comprised of the diseases babesiosis and anaplasmosis, has a large impact on cattle farming in several countries, as it compromises animal productivity. Using systematic review (SR)-meta-analysis (MA) methodology, our objective was to summarize and to investigate study characteristics associated with prevalence of Babesia spp. and Anaplasma marginale infection in Latin American cattle herds. Read More

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Extraordinary high level of propagation of in severe human babesiosis.

Parasitology 2022 May 20:1-15. Epub 2022 May 20.

Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, Russia.

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Splenic artery embolization for spontaneous splenic rupture due to Babesiosis: a case report.

Radiol Case Rep 2022 Jul 5;17(7):2304-2308. Epub 2022 May 5.

Radiology Department, Norwalk Hospital, 34 Maple St, Norwalk, CT, USA.

Babesiosis incidence in the United States has been increasing with an 11% rise between 2018 and 2019 based on the latest CDC annual summary, reaching its highest ever reported incidence. This primarily tick-borne disease is particularly prevalent in New England. Despite predominantly nonspecific and at times subtle symptoms, life-threatening complications do occur. Read More

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A case report of fatal feline babesiosis caused by Babesia canis in north western Spain.

BMC Vet Res 2022 May 14;18(1):177. Epub 2022 May 14.

Investigación en Sanidad Animal: Galicia (Grupo INVESAGA), Facultade de Veterinaria, Universidade de Santiago de Compostela, Pabellón I. Campus Universitario S/N, 27002, Lugo, Spain.

Background: In Europe, Babesia infections in cats are sporadic and only partial knowledge is currently available since the number of described cases including both the clinical presentation and the molecular identification of the Babesia species involved is limited. In the present case report, the clinical signs, the epidemiological data and the molecular results suggest that this is the first reported fatal case of feline babesiosis caused by Babesia canis.

Case Presentation: A six month old female European shorthair cat from north-western Spain died after being hospitalized for two days. Read More

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Establishment and Application of an Indirect Enzyme-Linked Immunosorbent Assay for Measuring GPI-Anchored Protein 52 (P52) Antibodies in -Infected Dogs.

Animals (Basel) 2022 May 6;12(9). Epub 2022 May 6.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

is a malaria-like protozoan that parasitizes the red blood cells of canids to cause babesiosis. Due to its high expression and essential function in the survival of parasites, the Glycosylphosphatidylinositol (GPI) anchor protein family is considered an excellent immunodiagnostic marker. Herein, we identified a novel GPI-anchored protein named as BgGPI52-WH with a size of 52 kDa; the recombinant BgGPI52-WH with high antigenicity and immunogenicity was used as a diagnostic antigen to establish a new iELISA method. Read More

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Tick-borne haemoparasitic diseases in small ruminants in Pakistan: Current knowledge and future perspectives.

Saudi J Biol Sci 2022 Apr 29;29(4):2014-2025. Epub 2021 Dec 29.

Department of Biology and Parasitology, Medical University of Lublin, Radziwillowska, Poland.

Livestock industry is an essential part of Pakistan's economy, and a variety of ruminants (including sheep and goats) are reared for the increasing demand of milk, meat and hide products. Haemoparasitic illnesses such as , and are a significant health risk for small ruminants in our country. Information regarding distribution patterns, the tick species involved and effective strategies to control tick-borne diseases (TBD) in goats and sheep of Pakistan is limited. Read More

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caused clinical babesiosis in a female Shih Tzu dog.

Vet Res Forum 2021 Dec 15;12(4):519-522. Epub 2021 Dec 15.

Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

A 2-year-old female Shih Tzu dog was submitted with the history of anorexia and depression for one week and no prior surgery. Fever and pale mucosa were noticed in physical examination. Microscopic examination of the Giemsa-stained blood smear disclosed large form of  and single to four pear-shaped merozoites within erythrocytes (RBCs). Read More

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December 2021

Molecular survey of Babesia parasites in Kenya: first detailed report on occurrence of Babesia bovis in cattle.

Parasit Vectors 2022 May 7;15(1):161. Epub 2022 May 7.

Department of Biochemistry, Faculty of Science and Technology, University of Nairobi, Nairobi, Kenya.

Background: Among protozoan parasites in the genus Babesia, Babesia bigemina is endemic and widespread in the East African region while the status of the more pathogenic Babesia bovis remains unclear despite the presence of the tick vector, Rhipicephalus microplus, which transmits both species. Recent studies have confirmed the occurrence of R. microplus in coastal Kenya, and although B. Read More

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[Role of systemic infections in canine kidney diseases].

Tierarztl Prax Ausg K Kleintiere Heimtiere 2022 Apr 6;50(2):124-136. Epub 2022 May 6.

Medizinische Kleintierklinik, Zentrum für klinische Tiermedizin, Ludwig-Maximilians-Universität München.

Kidney diseases represent a common problem as well as a frequent cause of death in dogs. Infectious agents may be responsible for glomerulopathies and acute kidney injuries. Many infections commonly associated with the development of immune complex glomerulonephritis in central and southern Europe are important as travel-associated diseases in Germany. Read More

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Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control .

Front Cell Infect Microbiol 2022 19;12:870852. Epub 2022 Apr 19.

Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA, United States.

is a tick-borne apicomplexan hemoprotozoan responsible for bovine babesiosis. The current drugs used for bovine babesiosis treatment have several drawbacks, including toxicity, the lack of effectiveness to clear the parasite, and potential to develop resistance. Identifying compounds that target essential and unique parasite metabolic pathways is a rational approach toward finding alternative drug treatments. Read More

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Babesia duncani as a model organism to study the development, virulence and drug susceptibility of intraerythrocytic parasites in vitro and in vivo.

J Infect Dis 2022 May 4. Epub 2022 May 4.

Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, USA.

Human babesiosis is a malaria-like illness caused by tick-borne intraerythrocytic Babesia parasites of the Apicomplexa phylum. Whereas several species of Babesia can cause severe disease in humans, the ability to propagate B. duncani both in vitro in human erythrocytes and in mice makes it a unique pathogen to study Babesia biology and pathogenesis. Read More

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Molecular survey and phylogenetic analysis of Babesia vogeli in dogs.

Sci Rep 2022 Apr 28;12(1):6988. Epub 2022 Apr 28.

Department of Pharmacy Practice, College of Pharmacy, Jazan University, Jizan, 82722, Saudi Arabia.

Canine babesiosis is a life-threatening haemoparasitic disease in dogs that is prevalent worldwide. In this study, the prevalence of Babesia vogeli (B. vogeli) was investigated in dogs from Egypt by using Polymerase Chain Reaction (PCR) assay, and associated risk factors were evaluated. Read More

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Severe Babesiosis With Heavy Parasitemia in an Immunocompetent Patient Treated Successfully With Red Cell Exchange Transfusion.

Cureus 2022 Mar 20;14(3):e23344. Epub 2022 Mar 20.

Pulmonary and Critical Care Medicine, Nassau University Medical Center, East Meadow, USA.

Babesiosis is a zoonotic disease caused by a protozoa . It is transmitted through a tick vector and affects red blood cells. The clinical manifestation of Babesiosis varies and can range from asymptomatic infection to fatal multi-organ failure and death. Read More

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Establishment of a Transient and Stable Transfection System for Using a Homologous Recombination Strategy.

Front Cell Infect Microbiol 2022 6;12:844498. Epub 2022 Apr 6.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.

Genetic modification provides an invaluable molecular tool to dissect the biology and pathogenesis of pathogens. However, no report is available about the genetic modification of , a pathogen responsible for human babesiosis that is widespread in North America, suggesting the necessity to develop a genetic manipulation method to improve the strategies for studying and understanding the biology of protozoan pathogens. The establishment of a genetic modification method requires promoters, selectable markers, and reporter genes. Read More

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and Human Babesiosis.

Pathogens 2022 Mar 25;11(4). Epub 2022 Mar 25.

Parasitology Reference and Research Laboratory, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.

is a genus of intraerythrocytic protozoan parasites belonging to the exclusively parasitic phylum Apicomplexa [... Read More

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The distribution of Dermacentor reticulatus in the Czech Republic re-assessed: citizen science approach to understanding the current distribution of the Babesia canis vector.

Parasit Vectors 2022 Apr 18;15(1):132. Epub 2022 Apr 18.

Department of Pathology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary Sciences, Brno, Czech Republic.

Background: The range of the ornate dog tick Dermacentor reticulatus is rapidly expanding in Europe. This tick species is the vector of canine babesiosis, caused by Babesia canis, and also plays a role in the transmission of Theileria equi and Babesia caballi in equids.

Methods: The geographic range of D. Read More

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Molecular investigation of Babesia caballi in horses from the state of Rio de Janeiro, Brazil: Epidemiological aspects associated with the infection.

Vet Parasitol Reg Stud Reports 2022 05 19;30:100709. Epub 2022 Feb 19.

Department of Animal Parasitology, Federal Rural University of Rio de Janeiro (UFRRJ), BR 465, Km 7, Seropedica, RJ 23890-000, Brazil.

The epidemiological aspects of Babesia caballi infection were evaluated in 516 horse samples from Rio de Janeiro, Brazil. The presence and infestation level of ticks on horses, breed conditions, and animal management were evaluated on each farm through an epidemiological questionnaire. The gene that codes for rhoptry-associated protein-1 (RAP-1) of B. Read More

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Babesiosis in cattle and ixodid tick distribution in Dasenech and Salamago Districts, southern Ethiopia.

Sci Rep 2022 Apr 16;12(1):6385. Epub 2022 Apr 16.

Jinka Town Municipal Abattoir Animal Health Team Leader, South Omo Zone, Jinka, Southern Ethiopia, Ethiopia.

Babesiosis, caused by protozoan parasites of the genus Babesia, and ixodid ticks are considered to be one of the most important causes that result in significant economic losses in cattle production worldwide, including in Ethiopia. A cross-sectional study was undertaken in the Dasenech and Salamago Districts of South Omo zone Ethiopia to determine the prevalence and associated risk factors of babesia infection and ixodid ticks of cattle using Giemsa-stained thin and thick film techniques and morphological identification keys for babesia species and tick identification, respectively. Out of 470 examined cattle, 102 (21. Read More

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Invasive raccoon (Procyon lotor) and raccoon dog (Nyctereutes procyonoides) as potential reservoirs of tick-borne pathogens: data review from native and introduced areas.

Parasit Vectors 2022 Apr 11;15(1):126. Epub 2022 Apr 11.

Department of Parasitology, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.

In recent decades, populations of the raccoon (Procyon lotor) and the raccoon dog (Nyctereutes procyonides) have increased and adapted to peri-urban and urban environments in many parts of the world. Their ability to rapidly colonize new territories, high plasticity and behavioral adaptation has enabled these two species to be considered two of the most successful invasive alien species. One of the major threats arising from continually growing and expanding populations is their relevant role in maintaining and transmitting various vector-borne pathogens among wildlife, domestic animals and humans. Read More

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Update on prevalence of Babesia canis and Rickettsia spp. in adult and juvenile Dermacentor reticulatus ticks in the area of Poland (2016-2018).

Sci Rep 2022 04 6;12(1):5755. Epub 2022 Apr 6.

Department of Eco-Epidemiology of Parasitic Diseases, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096, Warsaw, Poland.

Ornate dog tick, Dermacentor reticulatus is an important vector of Babesia canis, and Rickettsia spp. and other pathogens of veterinary and public health interest. The current study is the first to investigate the long-term changes in prevalence of these pathogens in expanding tick populations in Central Europe. Read More

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A Five-Week-Old Twin With Profound Anemia: A Case Report of Asymmetric Congenital Babesiosis.

Cureus 2022 Mar 2;14(3):e22774. Epub 2022 Mar 2.

Emergency Medicine, Baystate Medical Center, Springfield, USA.

We present a case report and review of the literature of congenital transmission of babesiosis in a five-week-old twin neonate evaluated for lethargy and difficulty with feeding. On presentation to the pediatric emergency department, the patient appeared pale and was found to be profoundly anemic with intraerythrocytic ringed parasites consistent with visible on a thin smear. The patient received a blood transfusion and was treated with a regimen of atovaquone and azithromycin with full recovery. Read More

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Active surveillance of ticks in peri-domestic areas of Indiana, Midwest United States.

J Vector Borne Dis 2021 Oct-Dec;58(4):352-358

Department of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington, Indiana, USA.

Background & Objectives: The incidence of Borreliosis, Anaplasmosis, Babesiosis and other tick-borne diseases acquired from private residential/peri-domestic areas has increased over the decades. However, tick activity and proportion of private residential properties with established tick populations remain unknown. The purpose of the current study was to determine the predictors of tick activity in peri-domestic areas. Read More

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Effect of methanolic extract from against the multiplication of several species and on cultures, and in mice.

Vet World 2022 Jan 20;15(1):76-82. Epub 2022 Jan 20.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan.

Background And Aim: Piroplasmosis is a serious disease that infects animals, inflicting significant economic losses in the livestock industry and animal trade worldwide. Anti-piroplasm drugs now on the market have demonstrated host toxicity and parasite resistance. As a result, developing more effective and safer anti-piroplasm drugs becomes an urgent issue. Read More

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January 2022

Unraveling the Complexity of the Rhomboid Serine Protease 4 Family of Using Bioinformatics and Experimental Studies.

Pathogens 2022 Mar 12;11(3). Epub 2022 Mar 12.

Instituto de Patobiología Veterinaria (IPVET), Centro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria-Consejo Nacional de Investigaciones Científicas y Técnicas (INTA-CONICET), Hurlingham 1686, Argentina.

, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans and , rhomboid serine protease 4 (ROM4) fulfills an essential role in host cell invasion. We thus investigated ROM4 coding genes; their genomic organization; their expression in in vitro cultured asexual (AS) and sexual stages (SS); and strain polymorphisms. Read More

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Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood.

Front Microbiol 2022 7;13:837621. Epub 2022 Mar 7.

Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York City, NY, United States.

Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting tick-borne agents, to test 158 whole blood specimens obtained from the Lyme Disease Biobank. These included samples from 98 individuals with signs and symptoms of acute Lyme disease, 25 healthy individuals residing in Lyme disease endemic areas, and 35 samples collected from patients admitted to the Massachusetts General Hospital or referred to the infectious disease clinic. Read More

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The Etiology, Incidence, Pathogenesis, Diagnostics, and Treatment of Canine Babesiosis Caused by Infection.

Animals (Basel) 2022 Mar 16;12(6). Epub 2022 Mar 16.

Small Animal Clinic, University of Veterinary Medicine and Pharmacy, 04001 Košice, Slovakia.

is one of the small species and the infection this pathogen causes is usually asymptomatic, which complicates the capture of potential parasite carriers. In endemic areas, especially in Asia, occurs quite often due to direct transmission by way of a tick vector. Due to the absence of vectors, its occurrence is described only sporadically in Europe; but, it is increasingly occurring in predisposed, so-called fighting breeds, especially the American pit bull terrier. Read More

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