5,147 results match your criteria Babesiosis


Cattle ticks and associated tick-borne pathogens in Burkina Faso and Benin: Apparent northern spread of Rhipicephalus microplus in Benin and first evidence of Theileria velifera and Theileria annulata.

Ticks Tick Borne Dis 2021 May 1;12(4):101733. Epub 2021 May 1.

Federal Public Service Public Health, food safety & environment, President services, Research coordination, Place victor Horta 40, 1060 Brussels, Belgium. Electronic address:

Babesiosis, theileriosis, anaplasmosis, and heartwater are tick-borne diseases that threaten livestock production in sub-Saharan Africa including Burkina Faso and Benin. For over a decade, these two bordering countries have been facing an invasion of the livestock by the tick Rhipicephalus microplus, a major vector for babesiosis, accidentally introduced in Benin in 2004. The molecular identification of tick-borne pathogens in this border area is of particular interest due to animals seasonal migration between the two countries. Read More

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Climate and the seasonal abundance of the tick Dermacentor reticulatus.

Med Vet Entomol 2021 May 4. Epub 2021 May 4.

School of Biological Sciences, University of Bristol, Bristol, U.K.

Dermacentor reticulatus (Ixodida: Ixodidae, Fabricius 1794) is one of the most widely distributed and abundant tick species in central Europe and is a vector for a range of pathogens. Nevertheless, many aspects of its ecology and distribution remain poorly understood. To quantify the seasonal abundance of this species in the U. Read More

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Tafenoquine is a Promising Drug Candidate for the Treatment of Babesiosis.

Antimicrob Agents Chemother 2021 May 3. Epub 2021 May 3.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan

Due to drug resistance, commonly used anti- drugs have limited efficacy against babesiosis, and inflict severe side effects. Tafenoquine (TAF) was approved by the U.S. Read More

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Pathogenesis of Borrelia burgdorferi and Babesia microti in TLR4-Competent and TLR4-dysfunctional C3H Mice.

Cell Microbiol 2021 May 2:e13350. Epub 2021 May 2.

Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Toll-like receptors (TLRs) are a class of membrane-spanning proteins of host cells. TLR2 and TLR4 are displayed on the surface of macrophages, neutrophils and dendritic cells and recognize structurally conserved microbial signatures defined as Pathogen associated molecular patterns (PAMPs). C3H mice are susceptible to tick-borne pathogens; Lyme disease causing Borrelia burgdorferi that manifests arthritis and carditis and Apicomplexan protozoan, Babesia microti (Bm) that causes significant parasitemia associated with erythrocytopenia and haemoglobinuria. Read More

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Simulated dynamics of southern cattle fever ticks (Rhipicephalus (Boophilus) microplus) in south Texas, USA: investigating potential wildlife-mediated impacts on eradication efforts.

Parasit Vectors 2021 May 1;14(1):231. Epub 2021 May 1.

Knipling-Bushland U.S. Livestock Insects Research Laboratory and Veterinary Pest Genomics Center, United States Department of Agriculture - Agricultural Research Service, Kerrville, TX, 78028, USA.

Background: Cattle fever ticks (CFT), Rhipicephalus (Boophilus) annulatus and R. (B.) microplus, are vectors of microbes causing bovine babesiosis and pose a threat to the economic viability of the US livestock industry. Read More

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A historical review of Babesia spp. associated with deer in Europe: Babesia divergens/Babesia divergens-like, Babesia capreoli, Babesia venatorum, Babesia cf. odocoilei.

Authors:
Angela Fanelli

Vet Parasitol 2021 Apr 22;294:109433. Epub 2021 Apr 22.

Department of Veterinary Sciences, University of Turin, Grugliasco, Turin, Italy; Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy. Electronic address:

This review is intended to provide an overview of the occurrence and diversity of Babesia spp. in European deer. Babesiosis is an emerging vector-borne disease with negative implications on animal and public health. Read More

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Assessment of Babesia bovis 6cys A and 6cys B as components of transmission blocking vaccines for babesiosis.

Parasit Vectors 2021 Apr 20;14(1):210. Epub 2021 Apr 20.

Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.

Background: Babesia bovis reproduces sexually in the gut of its tick vector Rhipicephalus microplus, which involves expression of 6cys A and 6cys B proteins. Members of the widely conserved 6cys superfamily are candidates for transmission blocking vaccines (TBV), but intricacies in the immunogenicity of the 6cys proteins in the related Plasmodium parasites required the identification of transmission blocking domains in these molecules for vaccine design. Hereby, the immunogenic efficacy of recombinant (r) B. Read More

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Recombinase polymerase amplification with lateral flow strip for detecting Babesia microti infections.

Parasitol Int 2021 Apr 16;83:102351. Epub 2021 Apr 16.

State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei 430070, China; Key Laboratory of Animal Epidemical Disease and Infectious Zoonoses, Ministry of Agriculture, Huazhong Agricultural University, Wuhan, Hubei 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei 430070, China. Electronic address:

Babesia microti is one of the most important pathogens causing humans and rodents babesiosis-an emerging tick-borne disease that occurs worldwide. At present, the gold standard for the detection of Babesia is the microscopic examination of blood smears, but this diagnostic test has several limitations. The recombinase polymerase amplification with lateral flow (LF-RPA) assay targeting the mitochondrial cytochrome oxidase subunit I (cox I) gene of B. Read More

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Comparative epidemiology and pathophysiology of patent and latent babesiosis caused by Babesia bigemina in buffaloes and cattle from different agroclimatic zones of Punjab State, India.

Trop Anim Health Prod 2021 Apr 17;53(2):264. Epub 2021 Apr 17.

Department of Veterinary Parasitology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, 141004, India.

To conduct comparative epidemiology of parasitologically positive (patent) and polymerase chain reaction positive (latent) cases of bovine babesiosis in Bet Region (low-lying areas adjoining Sutlej, Beas, Ravi, and Ghaggar rivers of Punjab) of diverse agroclimatic zones of Punjab state in relation to haematobiochemical parameters as patho-physiological markers, blood samples from 783 dairy animals (487 buffaloes and 296 cattle) were analysed parasitologically by Giemsa-stained blood smears (GSBS) and by molecular-based polymerase chain reaction (PCR) targeting SpeI-AvaI restriction fragment of Babesia bigemina. We ruled out the endemicity of the disease with 2.17% patent and 3. Read More

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One man, three tick-borne illnesses.

BMJ Case Rep 2021 Apr 16;14(4). Epub 2021 Apr 16.

Department of Internal Medicine, Providence Health and Services Oregon and Southwest Washington, Portland, Oregon, USA.

A 70-year-old man presented to the emergency department with fevers, ankle edema and nausea following a presumed insect bite on his ankle 1 month prior. On examination, he was febrile and had left leg pain with passive range of motion. Laboratory studies revealed anemia, thrombocytopenia, acute kidney injury and elevated aminotransaminases. Read More

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Babesiosis in the Emergency Department: A Case Report.

J Emerg Med 2021 Apr 13. Epub 2021 Apr 13.

Department of Emergency Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Background: Babesiosis, a tick-borne illness spread by Ixodes scapularis, is an emerging infectious disease in the Northeastern and upper Midwestern United States. Infection can present as a flu-like illness with anemia, thrombocytopenia, and jaundice. This disease can even be fatal in the immunocompromised or highly infected patient. Read More

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Coinfection of Ixodes scapularis (Acari: Ixodidae) Nymphs With Babesia spp. (Piroplasmida: Babesiidae) and Borrelia burgdorferi (Spirochaetales: Spirochaetaceae) in Wisconsin.

J Med Entomol 2021 Apr 15. Epub 2021 Apr 15.

Department of Entomology, College of Agricultural and Life Sciences, University of Wisconsin-Madison, 1630 Linden Drive, Madison, WI 53706, USA.

Borrelia burgdorferi, the spirochete that causes Lyme disease, is endemic and widespread in Wisconsin. Research in the northeastern United States has revealed a positive association between Babesia microti, the main pathogen that causes babesiosis in humans, and Bo. burgdorferi in humans and in ticks. Read More

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Efficacy of a water-based botanical acaricide formulation applied in portable spray box against the southern cattle tick, Rhipicephalus (Boophilus) microplus (Acari: Ixodidae), infesting cattle.

Ticks Tick Borne Dis 2021 Apr 3;12(4):101721. Epub 2021 Apr 3.

USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, and Veterinary Pest Genomics Center, 2700 Fredericksburg Rd, Kerrville, TX, 78028, United States.

Ectoparasitism result in annual losses to livestock producers estimated to reach billions of dollars in tropical and subtropical parts of the world where the southern cattle tick, Rhipicephalus (Boophilus) microplus, is established because this invasive pest is also a vector of pathogens causing bovine babesiosis and anaplasmosis. Reintroduction of R. microplus could be economically devastating for the cattle industry in the United States. Read More

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SPECIFIC MOLECULAR DETECTION OF PIROPLASMS AND CHARACTERIZATION OF β-TUBULIN FOR A NOVEL SPECIES IN SIKA DEER ().

J Zoo Wildl Med 2021 Apr;52(1):200-205

Laboratory of Wildlife Biology and Medicine, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan,

Piroplasms, which include spp. and spp., are protozoan parasites carried by ticks and commonly cause disease in animals and humans. Read More

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Cross-priming amplification targeting the 18S rRNA gene for the rapid diagnosis of Babesia bovis infection.

Ticks Tick Borne Dis 2021 Mar 23;12(4):101713. Epub 2021 Mar 23.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu, 730046, PR China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonosis, Yangzhou University, Yangzhou 225009, PR China. Electronic address:

Babesia bovis is a known causative agent of bovine babesiosis and is widely distributed across China. Rapid detection and accurate identification of B. bovis is essential for follow-up management and epidemiological investigations. Read More

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Biosurveillance and Research Needs Involving Area-Wide Systematic Active Sampling to Enhance Integrated Cattle Fever Tick (Ixodida: Ixodidae) Eradication.

J Med Entomol 2021 Apr 2. Epub 2021 Apr 2.

USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, 2700 Fredericksburg Road, Kerrville, TX 78028, USA.

The one-host cattle fever tick, Rhipicephalus (Boophilus) annulatus (Say), and southern cattle fever tick, Rhipicephalus (Boophilus) microplus (Canestrini), are important ectoparasitic pests of cattle, Bos taurus L., mostly for transmitting the causal agents of bovine babesiosis. Bovine babesiosis inflicted substantial cattle production losses in the United States before the vectors were eliminated by 1943, with the exception of a Permanent Quarantine Zone in South Texas, a buffer along the Mexico border where the invasive ixodids remain. Read More

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BIOLOGICAL METHOD FOR BABESIOSIS DETECTION: THE UNIFIED VERSION IN VIVO.

Authors:
Inna I Torianyk

Wiad Lek 2021 ;74(2):268-272

STATE INSTITUTION «MECHNIKOV INSTITUTE OF MICROBIOLOGY AND IMMUNOLOGY OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KHARKIV, UKRAINE.

Objective: The aim is to establish a unified version of the biological method for babesiosis detection in vivo.

Patients And Methods: Materials and methods: samples (n=257) of biological material of different origin were examined. These included: blood samples from patients (n=6) and cattle (n=15); salivary gland homogenates (n=28) from 147 imagoes of ticks of the family Ixodidae, 32 imagoes of Ixodes ricinus and 115 imagoes of Dermacentor reticulates; spleen homogenates (n=63) from mouse-like rodents (Muridae) of the genera Myodes, Microtus, Apodemus and Sylvaemus. Read More

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MACROMICROSCOPIC ARGUMENTATION OF THE PATHOGENETIC SCENARIO OF BABESIOSIS IN THE COORDINATE SYSTEM «PATHOGEN-CARRIER-RESERVOIR».

Authors:
Inna I Torianyk

Wiad Lek 2021 ;74(3 cz 1):436-440

STATE INSTITUTION «MECHNIKOV INSTITUTE OF MICROBIOLOGY AND IMMUNOLOGY OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KHARKIV, UKRAINE.

Objective: The aim is to get a thorough argument for the babesiosis pathogenetic scenario in the coordinate system «pathogen (Babesia spp.) - carrier (ticks of the Ixodoidea superfamily of the Ixodidea family) - reservoir (a susceptible organism)» with the emphasis on the epizootic/epidemic role of the carrier.

Patients And Methods: Materials and methods: The macromicroscopic method of research was used in order to maximize the clarification of the babesiosis scenario, its pathogenetic links, the connection of the latter with attacks of active stages of ixodes ticks, types of circulation of ontogenetic forms of Babesia spp. Read More

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The Impact of Tick-Borne Diseases on the Bone.

Microorganisms 2021 Mar 23;9(3). Epub 2021 Mar 23.

Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.

Tick-borne infectious diseases can affect many tissues and organs including bone, one of the most multifunctional structures in the human body. There is a scarcity of data regarding the impact of tick-borne pathogens on bone. The aim of this review was to survey existing research literature on this topic. Read More

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Circulation of Species and Their Exposure to Humans through .

Pathogens 2021 Mar 24;10(4). Epub 2021 Mar 24.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands.

Human babesiosis in Europe has been attributed to infection with and, to a lesser extent, with and which are all transmitted to humans through a bite of . These species circulate in the Netherlands, but autochthonous human babesiosis cases have not been reported so far. To gain more insight into the natural sources of these species, their presence in reservoir hosts and in was examined. Read More

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Detection of in Ticks Collected in Southern Ontario, Canada.

Pathogens 2021 Mar 10;10(3). Epub 2021 Mar 10.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA.

Tick-borne zoonotic diseases have an economic and societal impact on the well-being of people worldwide. In the present study, a high frequency of , a red blood cell parasite, was observed in the Huronia area of Ontario, Canada. Notably, 71% (15/21) blacklegged ticks, , collected from canine and feline hosts were infected with . Read More

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A Comparative Genomic Study of Attenuated and Virulent Strains of .

Pathogens 2021 Mar 8;10(3). Epub 2021 Mar 8.

CENID-Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias, Jiutepec, Morelos 62550, Mexico.

Cattle babesiosis is a socio-economically important tick-borne disease caused by Apicomplexa protozoa of the genus that are obligate intraerythrocytic parasites. The pathogenicity of parasites for cattle is determined by the interaction with the host immune system and the presence of the parasite's virulence genes. A strain that has been maintained under a microaerophilic stationary phase in in vitro culture conditions for several years in the laboratory lost virulence for the bovine host and the capacity for being transmitted by the tick vector. Read More

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Update on prevalence and distribution pattern of tick-borne diseases among humans in India: a review.

Parasitol Res 2021 May 2;120(5):1523-1539. Epub 2021 Apr 2.

School of Environment and Natural Resources, Doon University, Dehradun, Uttarakhand, 248 012, India.

In the present scenario, tick-borne diseases (TBDs) are well known for their negative impacts on humans as well as animal health in India. The reason lies in their increased incidences due to global warming, environmental and ecological changes, and availability of suitable habitats. On a global basis, they are now considered a serious threat to human as well as livestock health. Read More

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Three Babesia species in Ixodes ricinus ticks from migratory birds in Sweden.

Parasit Vectors 2021 Apr 1;14(1):183. Epub 2021 Apr 1.

Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Background: Migratory birds can cross geographical and environmental barriers and are thereby able to facilitate transmission of tick-borne pathogens both as carriers of infected ticks and as reservoirs of pathogenic microorganisms. Ixodes ricinus is one of the most abundant tick species in the Northern Hemisphere and a main vector of several Babesia species, some which pose a potential threat to human and animal health. At present only two cases of overt babesiosis in humans have so far been reported in Sweden. Read More

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Babesia spp. and Anaplasma phagocytophilum in free-ranging wild ungulates in central Austria.

Ticks Tick Borne Dis 2021 Mar 23;12(4):101719. Epub 2021 Mar 23.

Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria. Electronic address:

Free-ranging wild ungulates are widespread in Austria, and act as hosts (i.e. feeding hosts) for ticks, including Ixodes ricinus, and as reservoir hosts for pathogens transmitted by I. Read More

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Survey on tick distribution and tick-borne pathogens in Daejeon and adjacent areas in South Korea.

Ticks Tick Borne Dis 2021 Mar 15;12(4):101711. Epub 2021 Mar 15.

Daejeon Metropolitan City Institute of Health and Environment, 407 Daehak-ro, Yuseong-gu, Daejeon, 34142, Republic of Korea.

Ticks (Ixodidae, also known as hard ticks) as principal vectors of zoonotic diseases such as severe fever with thrombocytopenia syndrome (SFTS), Lyme borreliosis, relapsing fever, anaplasmosis, ehrlichiosis, babesiosis, coxiellosis (Q fever), and tularemia pose a major public health threat. This study was conducted to identify the distribution profile of ticks and tick-borne pathogens in Daejeon and the adjacent areas in South Korea, where no such epidemiological study has been conducted. From April to October 2019, 16,765 ticks were collected from three genera and four species: Haemaphysalis longicornis (n = 14,949; 89. Read More

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Prevalence of tick-borne haemoparasites and their perceived co-occurrences with viral outbreaks of FMD and LSD and their associated factors.

Heliyon 2021 Mar 16;7(3):e06479. Epub 2021 Mar 16.

Department of Parasitology, Faculty of Veterinary Medicine, Alexandria University, Abbis10, P.O. Box 21917, Egypt.

Species of , , and are Tick-borne pathogens (TBPs) that are prevalent throughout the world, particularly in the tropical and subtropical regions. Associated diseases of , and , respectively, represents a major threat to livestock production in many countries. TBPs have a high prevalence in different geographical locations in Egypt. Read More

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Botanical Medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia Demonstrate Inhibitory Activity Against Babesia duncani.

Front Cell Infect Microbiol 2021 8;11:624745. Epub 2021 Mar 8.

State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Human babesiosis is a CDC reportable disease in the United States and is recognized as an emerging health risk in multiple parts of the world. The current treatment for human babesiosis is suboptimal due to treatment failures and unwanted side effects. Although was first described almost 30 years ago, further research is needed to elucidate its pathogenesis and clarify optimal treatment regimens. Read More

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The key to egress? Babesia bovis perforin-like protein 1 (PLP1) with hemolytic capacity is required for blood stage replication and is involved in the exit of the parasite from the host cell.

Int J Parasitol 2021 Mar 20. Epub 2021 Mar 20.

Instituto de Agrobiotecnología y Biología Molecular (IABIMO) INTA - CONICET, De Los Reseros y Dr. Nicolás Repetto s/n, P.O. Box 25 (B1712WAA), Castelar, Buenos Aires, Argentina. Electronic address:

Bovine babesiosis is a tick-borne disease caused by apicomplexan parasites of the Babesia genus that represents a major constraint to livestock production worldwide. Currently available vaccines are based on live parasites which have archetypal limitations. Our goal is to identify candidate antigens so that new and effective vaccines against Babesia may be developed. Read More

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