190 results match your criteria BMJ paediatrics open[Journal]


Cross-validated prediction model for severe adverse neonatal outcomes in a term, non-anomalous, singleton cohort.

BMJ Paediatr Open 2019 15;3(1):e000424. Epub 2019 Mar 15.

Mater Research, Mater Research Institute/University of Queensland, Brisbane, Queensland, Australia.

Objective: The aim of this study was to develop a predictive model using maternal, intrapartum and ultrasound variables for a composite of severe adverse neonatal outcomes (SANO) in term infants.

Design: Prospectively collected observational study. Mixed effects generalised linear models were used for modelling. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422248PMC
March 2019
6 Reads

Ultrasound imaging versus palpation method for diagnostic lumbar puncture in neonates and infants: a systematic review and meta-analysis.

BMJ Paediatr Open 2019 15;3(1):e000412. Epub 2019 Mar 15.

Centre for Evidence-based Health Care, Faculty of Medicine and Health Sciences Stellenbosch University, Tygerberg, Cape Town, South Africa.

Importance: Lumbar puncture (LP) failure rates vary and can be as high as 65%. Ultrasound guidance could increase the success of performing LP.

Objective: To summarise the evidence on the use of ultrasound guidance versus palpation method for LP. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422243PMC
March 2019
1 Read

Health examinations of child migrants in Europe: screening or assessment of healthcare needs?

BMJ Paediatr Open 2019 1;3(1):e000411. Epub 2019 Mar 1.

Section for Health Services Research, Danish Research Centre for Migration, Ethnicity and Health (MESU), Copenhagen, Denmark.

Background: More than 800 000 asylum-seeking children were registered in Europe during 2015-2017. Many of them arrived with accumulated needs of healthcare. In this study, we examined the legislation for health examinations on arrival for migrant children in the EU/EAA area. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422244PMC

Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study.

BMJ Paediatr Open 2019 4;3(1):e000409. Epub 2019 Mar 4.

Paediatric Department, London North West Healthcare NHS Trust, London, UK.

Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted with ARI fulfilling the WHO criteria for bronchiolitis. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422239PMC
March 2019
1 Read

Management of neonatal jaundice in low- and lower-middle-income countries.

BMJ Paediatr Open 2019 14;3(1):e000408. Epub 2019 Feb 14.

Paediatrics, Division of Neonatology, Erasmus MC - Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422246PMC
February 2019
1 Read

What do families want to improve in the management of paediatric febrile neutropenia during anti-cancer treatment? Report of a patient/public involvement group.

BMJ Paediatr Open 2019 1;3(1):e000398. Epub 2019 Mar 1.

Centre for Reviews and Dissemination, University of York, Leeds, UK.

Background: This study reports how parents and young people who had an experience offebrile neutropenia (FN) improved the design of a trial to inform the management of this condition. Five parents, a young person who had completed treatment and three clinician-researchers contributed.

Methods: The group was formed after an invitation on social media and met via video conference. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422240PMC

EBV-requisitioning physicians' guess on fatigue state 6 months after acute EBV infection.

BMJ Paediatr Open 2019 1;3(1):e000390. Epub 2019 Mar 1.

Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.

We assessed referring medical practitioner's ability to predict chronic fatigue development in adolescents presenting with acute infectious mononucleosis. Compared with being predicted as and were both strongly associated with developing fatigue 6 months later (OR 2.5, 95% CI 1. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422241PMC
March 2019
1 Read

Trends in investigations of abuse or neglect referred by hospital personnel in Ontario.

BMJ Paediatr Open 2019 4;3(1):e000386. Epub 2019 Feb 4.

Division of Haematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Background: There is a dearth of literature surrounding mandated reporters to child welfare services in the Canadian context. This paper examines 20 years of reporting patterns from hospitals, which represent 5% of all referrals to child welfare services in Ontario.

Methods: The Ontario Incidence Study of Reported Child Abuse and Neglect (OIS) is a representative study that has taken place every 5 years since 1993. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422247PMC
February 2019

Arterial flow patterns in healthy transitioning near-term neonates.

BMJ Paediatr Open 2019 14;3(1):e000333. Epub 2019 Feb 14.

Libin Cardiovascular Institute of Alberta, University of Calgary, AB, Calgary, AB, Canada.

Objective: Significant haemodynamic changes occur at delivery impacting organ blood flow distribution. We aimed to characterise Doppler indices patterns over time in three different organs (brain, gut and kidney) and test them as measures of vascular resistance.

Design: Observational cohort study. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422249PMC
February 2019
1 Read

Burden of adverse childhood experiences in children attending paediatric clinics in South Western Sydney, Australia: a retrospective audit.

BMJ Paediatr Open 2019 8;3(1):e000330. Epub 2019 Mar 8.

Department of Community Paediatrics, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.

Objectives: Adverse childhood experiences (ACE) are associated with poor short, medium and long-term health outcomes. South Western Sydney (SWS) has a large culturally diverse population, including many disadvantaged population groups. Our aims were to determine the burden of ACE in children attending community paediatric (CP) clinics using a purposefully developed ACE checklist, and explore any association with developmental health of children. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422242PMC

Adverse health effects of recruiting child soldiers.

BMJ Paediatr Open 2019 25;3(1):e000325. Epub 2019 Feb 25.

Integrated Child Health QI Fellow and Paediatric Registrar, London, UK.

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http://dx.doi.org/10.1136/bmjpo-2018-000325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422323PMC
February 2019

Paediatric neurodisability and sleep disorders: clinical pathways and management strategies.

BMJ Paediatr Open 2019 7;3(1):e000290. Epub 2019 Mar 7.

Paedatric Neurosciences, Evelina London Children's Healthcare, London, UK.

Sleep disorders are common in children with neurodisability. Their presentation is often complex. This complexity of presentation can make sleep disorders in children with neurodisability daunting to diagnose and manage. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422245PMC

Family talk intervention in paediatric oncology: a pilot study protocol.

BMJ Paediatr Open 2019 31;3(1):e000417. Epub 2019 Jan 31.

Department of Health Care Sciences, Palliative Research Centre, Ersta Sköndal Bräcke University College, Stockholm, Sweden.

Introduction: There is evidence that families with a child diagnosed with cancer need psychosocial support throughout the illness trajectory. Unfortunately, there is little research into psychosocial interventions for such families, especially interventions where the entire family is involved. The aim of this pilot study is therefore to evaluate a psychosocial intervention, the family talk intervention (FTI), in paediatric oncology in terms of study feasibility and potential effects. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361369PMC
January 2019
2 Reads

Effect of bariatric surgery before pregnancy on the vascular function in the offspring: protocol of a cross-sectional follow-up study.

BMJ Paediatr Open 2019 31;3(1):e000405. Epub 2019 Jan 31.

Research Unit Organ Systems, Department of Development and Regeneration, Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Leuven, Belgium.

Background: The offspring of obese pregnant women are at risk for adverse metabolic, inflammatory and cardiovascular programming. Comprehensive long-term data are lacking on the contribution of changes in maternal weight after bariatric surgery before pregnancy compared with lifestyle interventions during pregnancy on the cardiovascular programming of the offspring.

Methods: EFFECTOR is designed as a cross-sectional cohort follow-up study targeting the children of different groups of women who were previously studied during their pregnancy. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361362PMC
January 2019
1 Read

What is the timeliness and extent of health service use of Victorian (Australia) children in the year after entry to out-of-home care? Protocol for a retrospective cohort study using linked administrative data.

BMJ Paediatr Open 2019 31;3(1):e000400. Epub 2019 Jan 31.

Policy and Equity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.

Introduction: Children entering out-of-home care have high rates of health needs across all domains of health. To identify these needs early and optimise long-term outcomes, routine health assessment on entry to care is recommended by child health experts and included in policy in many jurisdictions. If effective, this ought to lead to high rates of health service use as needs are addressed. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361372PMC
January 2019
2 Reads

Can social robots help children in healthcare contexts? A scoping review.

BMJ Paediatr Open 2019 31;3(1):e000371. Epub 2019 Jan 31.

Department of Psychological Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Objective: To review research on social robots to help children in healthcare contexts in order to describe the current state of the literature and explore future directions for research and practice.

Design: Scoping review.

Data Sources: Engineering Village, IEEE Xplore, Medline, PsycINFO and Scopus databases were searched up until 10 July 2017. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361370PMC
January 2019
1 Read

Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey.

BMJ Paediatr Open 2019 31;3(1):e000365. Epub 2019 Jan 31.

Institute of Clinical Pharmacy and Pharmacotherapy, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

Objective: To characterise heart failure (HF) maintenance pharmacotherapy for children across Europe and investigate how angiotensin-converting enzyme inhibitors (ACE-I) are used in this setting.

Methods: A Europe-wide web-based survey was conducted between January and May 2015 among European paediatricians dedicated to cardiology.

Results: Out of 200-eligible, 100 physicians representing 100 hospitals in 27 European countries participated. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361374PMC
January 2019
5 Reads

Factors associated with adverse childhood experiences in Scottish children: a prospective cohort study.

BMJ Paediatr Open 2019 31;3(1):e000340. Epub 2019 Jan 31.

Farr Institute/Scottish Collaboration for Public Health Research and Policy, University of Edinburgh, Edinburgh, UK.

Background And Objectives: Adverse childhood experiences (ACEs) have been associated with a range of poorer health and social outcomes throughout the life course; however, to date they have primarily been conducted retrospectively in adulthood. This paper sets out to determine the prevalence of ACEs at age 8 in a recent prospective birth cohort and examine associations between risk factors in the first year and cumulative ACEs.

Design: This study uses the Growing Up in Scotland Birth Cohort 1, in which children born in Scotland in 2004/5 were identified using Child Benefit Records and followed up for 7 years (n. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
Publisher Site
http://dx.doi.org/10.1136/bmjpo-2018-000340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361326PMC
January 2019
11 Reads

Prospective observational study of universal newborn eye screening in a hospital and community setting in New Zealand.

BMJ Paediatr Open 2019 31;3(1). Epub 2019 Jan 31.

Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Objective: Early detection of ocular abnormalities in newborn infants is essential for timely diagnosis and treatment. This study aimed to assess wide-field digital imaging for universal newborn eye screening (UNES) to determine the prevalence of ocular abnormalities, including retinal haemorrhages, in newborn infants in New Zealand.

Design: Prospective ocular screening study of infants. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361368PMC
January 2019

Where are the paediatricians? An international survey to understand the global paediatric workforce.

BMJ Paediatr Open 2019 31;3(1). Epub 2019 Jan 31.

Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA.

Objective: Our primary objective was to examine the global paediatric workforce and to better understand geographic differences in the number of paediatricians globally. Secondary objectives were to describe paediatric workforce expectations, who provides children with preventative care and when children transition out of paediatric care.

Design: Survey of identified paediatric leaders in each country. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361365PMC
January 2019

Children on the move in Europe: a narrative review of the evidence on the health risks, health needs and health policy for asylum seeking, refugee and undocumented children.

BMJ Paediatr Open 2019 31;3(1). Epub 2019 Jan 31.

Clinical Epidemiology, Department of Medicine, Karolinska Institutet and Centre for Health Equity Studies (CHESS), Karolinska Institutet/Stockholm University, Stockholm, Sweden.

Background: Europe has experienced a marked increase in the number of children on the move. The evidence on the health risks and needs of migrant children is primarily from North America and Australia.

Objective: To summarise the literature and identify the major knowledge gaps on the health risks and needs of asylum seeking, refugee and undocumented children in Europe in the early period after arrival, and the ways in which European health policies respond to these risks and needs. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361329PMC
January 2019

Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study.

BMJ Paediatr Open 2019 23;3(1):e000382. Epub 2019 Jan 23.

Division of Pediatric Medicine, Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.

Objectives: To describe the acceptability, safety and effectiveness of neuromuscular electrical stimulation (NMES) in infants and young children with neurological impairment (NI) who have severe dysphagia.

Design: A prospective pilot study using a before and after study design.

Setting: The Hospital for Sick Children, Toronto, Canada. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347906PMC
January 2019
3 Reads

Trends in road transport collision deaths in the Irish paediatric population: a retrospective review of mortality data, 1991-2015.

BMJ Paediatr Open 2019 23;3(1):e000361. Epub 2019 Jan 23.

RCSI Department of Paediatrics, Temple Street Children's University Hospital, Dublin, Ireland.

Objective: To establish the incidence of road transport collision (RTC) fatalities in the Irish paediatric population, examining trends in fatality rates over a period of 25 years, during which several national road safety interventions were implemented.

Study Design: Retrospective review of death registration details of children 0-19 years in Ireland between January 1991 and December 2015. Trends in mortality rates were investigated using average annual per cent change and Poisson regression analysis. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347854PMC
January 2019

Parental perspective on neonatal outcomes.

Authors:
Mandy Daly

BMJ Paediatr Open 2019 13;3(1):e000404. Epub 2019 Jan 13.

Director of Advocacy and Policy Making, Irish Neonatal Health Alliance, Bray, Ireland.

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http://dx.doi.org/10.1136/bmjpo-2018-000404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340574PMC
January 2019
4 Reads

Improving outcomes for neonates with gastroschisis in low-income and middle-income countries: a systematic review protocol.

BMJ Paediatr Open 2018 27;2(1):e000392. Epub 2018 Dec 27.

King's Centre for Global Health and Health Partnerships, School of Population Health and Environmental Sciences, King's College London, London, UK.

Introduction: There is a significant disparity in outcomes for neonates with gastroschisis in high-income countries (HICs) compared with low-income and middle-income countries (LMICs). Many LMICs report mortality rates between 75% and 100% compared with <4% in HICs.

Aim: To undertake a systematic review identifying postnatal interventions associated with improved outcomes for gastroschisis in LMICs. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326322PMC
December 2018
5 Reads

Can adoption at an early age protect children at risk from depression in adulthood? A Swedish national cohort study.

BMJ Paediatr Open 2018 6;2(1):e000353. Epub 2018 Dec 6.

Clinical Epidemiology/Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Objective: Our aim was to investigate whether the risk of depression in adulthood in children raised by substitute parents from an early age differ by care arrangements.

Methods: Register study in Swedish national cohorts born 1972-1981, with three study groups of children raised in adoptive or foster homes with care starting before the age of 2 years and a comparison majority population group. Cox regression estimated HRs of prescribed antidepressive medication and specialised psychiatric care with a diagnosis of depression in adulthood during 2006-2012. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307555PMC
December 2018

Intestinal failure after necrotising enterocolitis: incidence and risk factors in a Swedish population-based longitudinal study.

BMJ Paediatr Open 2018 4;2(1):e000316. Epub 2018 Dec 4.

Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Background And Objective: Paediatric intestinal failure (IF) is a disease entity characterised by gut insufficiency often related to short bowel syndrome. It is commonly caused by surgical removal of a large section of the small intestine in association with necrotising enterocolitis (NEC), which usually affects premature infants. This study investigated the incidence and risk of IF in preterm infants with or without NEC. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307589PMC
December 2018
1 Read

Cultural considerations for informed consent in paediatric research in low/middle-income countries: a scoping review.

BMJ Paediatr Open 2018 5;2(1):e000298. Epub 2018 Dec 5.

Centre for Research in Indigenous Health, Wuqu' Kawoq | Maya Health Alliance, Tecpán, Guatemala.

Introduction: Conducting research with children in low/middle-income countries (LMIC) requires consideration of socioeconomic inequalities and cultural and linguistic differences. Our objective was to survey the literature on informed consent in paediatric LMIC research, assessing for practical guidance for culturally and linguistically appropriate procedures.

Methods: We conducted a scoping review on informed consent in paediatric LMIC research searching the PubMed, Web of Science and PsycINFO databases. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
Publisher Site
http://dx.doi.org/10.1136/bmjpo-2018-000298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307601PMC
December 2018
5 Reads

Adolescent's descriptions of fatigue, fluctuation and payback in chronic fatigue syndrome/myalgic encephalopathy (CFS/ME): interviews with adolescents and parents.

BMJ Paediatr Open 2018 4;2(1):e000281. Epub 2018 Dec 4.

Centre for Academic Child Health, University of Bristol, Bristol, UK.

Objective: As part of a larger qualitative study to explore outcomes important in paediatric chronic fatigue syndrome/myalgic encephalopathy (CFS/ME) and what improvements in fatigue and disability are key, interviews were undertaken with adolescents and their parents. This paper focuses on their descriptions of fatigue, fluctuation of symptoms and payback.

Design And Setting: Semistructured qualitative interviews were undertaken between December 2014 and February 2015. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307594PMC
December 2018

Consent and recruitment: the reporting of paediatric trials published in 2012.

BMJ Paediatr Open 2018 26;2(1):e000369. Epub 2018 Nov 26.

Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Alberta, Canada.

Objectives: We evaluated 300 paediatric trials to determine: the consent and recruitment strategies used, who trial information was targeted to, how incentives were used and if they achieved their recruitment targets.

Methods: For this cross-sectional evaluation, we searched the Cochrane Central Register of Controlled Trials for paediatric trials published in 2012 and randomly selected 300 that reported on outcomes for participants aged ≤21 years. We collected data on consent and recruitment procedures for each trial and undertook descriptive analyses in SPSS statistics V. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267313PMC
November 2018
1 Read

Why health information needs to be accessible to all.

BMJ Paediatr Open 2018 10;2(1):e000352. Epub 2018 Oct 10.

HIFA, Oxford, UK.

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http://dx.doi.org/10.1136/bmjpo-2018-000352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267305PMC
October 2018

Can microRNA profiles predict corticosteroid responsiveness in childhood nephrotic syndrome? A study protocol.

BMJ Paediatr Open 2018 17;2(1):e000319. Epub 2018 Nov 17.

Department of Pediatric Nephrology, Armed Forces Medical College, Pune, Maharashtra, India.

Introduction: In last few years, several studies have revealed the remarkable stability of extracellular microRNAs (miRNAs) circulating in the blood or excreted in the urine and underscored their key importance as biomarkers of certain diseases. Since miRNA in urinary sediment is relatively stable and easily quantified, it has the potential to be developed as a biomarker for disease diagnosis and monitoring. Identification of serum and urinary levels of certain miRNAs may assist in the diagnosis and assessment of disease activity in patients with nephrotic syndrome (NS). Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267312PMC
November 2018
1 Read

Clinical indications and scanning protocols for chest CT in children with cystic fibrosis: a survey of UK tertiary centres.

BMJ Paediatr Open 2018 27;2(1):e000367. Epub 2018 Oct 27.

Institute of Applied Clinical Science, Keele University, Keele, UK.

Objectives: Chest CT is increasingly used to monitor disease progression in children with cystic fibrosis (CF) but there is no national guideline regarding its use. Our objective was to assess the indications for undertaking chest CT and the protocols used to obtain scans.

Design Setting And Participants: An electronic questionnaire was developed to assess clinicians views on chest CT in children with CF. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242016PMC
October 2018
17 Reads

Extubation from high-frequency oscillatory ventilation in extremely low birth weight infants: a prospective observational study.

BMJ Paediatr Open 2018 9;2(1):e000350. Epub 2018 Nov 9.

Unità Operativa Complessa di Neonatologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Objective: To evaluate if weaning from high-frequency oscillatory ventilation (HFOV) directly to a non-invasive mode of respiratory support is feasible and results in successful extubation in extremely low birth weight (ELBW) infants.

Design: Prospective observational study.

Setting: Tertiary neonatal intensive care unit. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242018PMC
November 2018
1 Read

Using laxatives and/or enemas to accelerate the diagnosis in children presenting with acute abdominal pain: a randomised controlled trial study protocol.

BMJ Paediatr Open 2018 9;2(1):e000341. Epub 2018 Nov 9.

Division of Pediatric Surgery, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Introduction: Many children with acute abdominal pain and suspicion of appendicitis are diagnosed with constipation. Nevertheless, it can be difficult to differentiate between acute constipation and acute appendicitis because of similar symptoms and lack of diagnostic criteria. Consequently, constipation is often missed despite repeated consultations at the emergency department. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241996PMC
November 2018
15 Reads

Retrospective study of haemophagocytic syndrome hospitalisations in children in the USA.

BMJ Paediatr Open 2018 9;2(1):e000337. Epub 2018 Nov 9.

Division of Pediatric Critical Care, Duke Children's Hospital, Duke University, Durham, North Carolina, USA.

Introduction: The haemophagocytic syndrome (HS) is a rare condition that presents with uncontrolled inflammation leading to multiorgan failure and is associated with significant morbidity and mortality. Current national estimates of children hospitalised due to HS are unknown. Characterising and understanding the burden of HS-related hospitalisations at a national level is the initial step in optimising the overall care. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242022PMC
November 2018
1 Read

Impact of health behaviours and deprivation on well-being in a national sample of English young people.

BMJ Paediatr Open 2018 9;2(1):e000335. Epub 2018 Nov 9.

Population, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, London, UK.

Objective: To determine the modifiable factors influencing well-being in boys and girls by accounting for deprivation, ethnicity and clustering within local authorities.

Methods: We used data from a very large nationally representative survey, the What About Youth study involving 120 115 adolescents aged 15 years. Our outcome measure of mental well-being was the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS). Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241972PMC
November 2018
4 Reads

Childhood injuries in Oman: retrospective review of a multicentre trauma registry data.

BMJ Paediatr Open 2018 9;2(1):e000310. Epub 2018 Nov 9.

Johns Hopkins International Injury Research Unit, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Objectives: Injuries are among the top causes of hospital-based mortality for adults in Oman. However, little is known about the distribution and risk of injuries among children. This paper describes the epidemiology and risk factors for childhood injuries (0-15 years of age), in two hospitals of Oman. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242029PMC
November 2018
1 Read

Parent, patient and clinician perceptions of outcomes during and following neonatal care: a systematic review of qualitative research.

BMJ Paediatr Open 2018 9;2(1):e000343. Epub 2018 Oct 9.

Neonatal Medicine, Imperial College London, London, UK.

Objective: Multiple outcomes can be measured in infants that receive neonatal care. It is unknown whether outcomes of importance to parents and patients differ from those of health professionals. Our objective was to systematically map neonatal care outcomes discussed in qualitative research by patients, parents and healthcare professionals and test whether the frequency with which outcomes are discussed differs between groups. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203019PMC
October 2018
3 Reads

Assessment of the performance of blood glucose monitoring systems for monitoring dysglycaemia in neonatal patients.

BMJ Paediatr Open 2018 23;2(1):e000339. Epub 2018 Oct 23.

Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.

Objective: To validate a three-step protocol that assesses the clinical risk associated with using blood glucose monitoring systems (BGMS) in neonates for the management of dysglycaemia.

Method: The three-step validation approach included confirmation of the accuracy of the reference method using National Institute of Standards and Technology (NIST) glucose standards, assessment of analytical risk performed on whole blood collected from paediatric patients routinely tested for glucose and a clinical risk assessment performed using heel stick capillary samples collected from 147 new-born babies and neonates admitted to intensive care. BGMS glucose measurements were compared with the NIST aligned laboratory reference method. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203032PMC
October 2018
2 Reads

Spirometry monitoring in asthmatic children in Lombardy Region, Italy.

BMJ Paediatr Open 2018 9;2(1):e000334. Epub 2018 Oct 9.

Laboratory for Mother and Child Health, Department of Public Health, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Objectives: To evaluate the diagnostic and therapeutic approaches in a cohort of asthmatic children before and after starting drug therapy.

Methods: Data were retrieved from administrative databases of the Lombardy Region. The study population was composed of 78 184 children born in the Lombardy Region in 2002 and followed until their 10th birthday. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203055PMC
October 2018
10 Reads

Serum concentrations of endothelial cell adhesion molecules and their shedding enzymes and early onset sepsis in newborns in Suriname.

BMJ Paediatr Open 2018 9;2(1):e000312. Epub 2018 Oct 9.

Department of Pediatrics, Tergooi Hospitals, Blaricum, The Netherlands.

Background: Early onset sepsis (EOS) is defined as onset of sepsis within 72 hours after birth. Leucocyte-endothelial interactions play a pivotal part in EOS pathophysiology. Endothelial cell adhesion molecules (CAMs) orchestrate these interactions and their soluble isoforms (sCAMs) are released into the vasculature by enzymes called sheddases. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203012PMC
October 2018
9 Reads

Maternal attitude towards delaying puberty in girls with and without a disability: a questionnaire-based study from the United Arab Emirates.

BMJ Paediatr Open 2018 9;2(1):e000306. Epub 2018 Oct 9.

Paediatric Department, Mediclinic City Hospital, Dubai, N/A, United Arab Emirates.

Background: Parental anxiety about the impact of puberty/menses, particularly in girls with severe disability leads to seeking therapeutic pubertal suppression. We aim to explore maternal attitudes and reasons for seeking pubertal suppression.

Methods: Mothers of girls receiving gonadotropin -releasing hormone analogue therapy in Mafraq hospital, Abu Dhabi were enrolled in the study. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203014PMC
October 2018
10 Reads

New anthropometric classification scheme of preoperative nutritional status in children: a retrospective observational cohort study.

BMJ Paediatr Open 2018 12;2(1):e000303. Epub 2018 Oct 12.

British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Objective: WHO uses anthropometric classification scheme of childhood acute and chronic malnutrition based on low body mass index (BMI) ('wasting') and height for age ('stunting'), respectively. The goal of this study was to describe a novel two-axis nutritional classification scheme to (1) characterise nutritional profiles in children undergoing abdominal surgery and (2) characterise relationships between preoperative nutritional status and postoperative morbidity.

Design: This was a retrospective observational cohort study. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203011PMC
October 2018
13 Reads

High body mass index in children with sickle cell disease: a retrospective single-centre audit.

BMJ Paediatr Open 2018 23;2(1):e000302. Epub 2018 Oct 23.

Department of Haematological Medicine, King's College London, London, UK.

Objective: To assess the prevalence of high body mass index (BMI) in children with sickle cell disease and assess correlation between BMI and disease severity.

Design: Retrospective chart review followed by statistical analysis.

Setting: A single tertiary paediatric clinic in inner city London. Read More

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202990PMC
October 2018
16 Reads

Impact of punitive immigration policies, parent-child separation and child detention on the mental health and development of children.

Authors:
Laura C N Wood

BMJ Paediatr Open 2018 26;2(1):e000338. Epub 2018 Sep 26.

Department of Sociology, Lancaster University, Lancaster, UK.

In April 2018, the US government introduced a 'zero tolerance' illegal immigration control strategy at the US-Mexico border resulting in the detention of all adults awaiting federal prosecution for illegal entry and the subsequent removal of their children to separate child shelters across the USA. By June 2018, over 2300 immigrant children, including infants, had been separated from their parents for immigration purposes. Media reports and scenes of distraught families ignited global condemnation of US immigration policy and fresh criticism of immigration detention practices. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173255PMC
September 2018

Developmental outcomes of an individualised complementary feeding intervention for stunted children: a substudy from a larger randomised controlled trial in Guatemala.

BMJ Paediatr Open 2018 3;2(1):e000314. Epub 2018 Oct 3.

Wuqu' Kawoq, Maya Health Alliance, Santiago Sacatepéquez, Guatemala.

Objective: Stunting is a common cause of early child developmental delay; Guatemala has the fourth highest rate of stunting globally. The goal of this study was to examine the impact of an intensive community health worker-led complementary feeding intervention on early child development in Guatemala. We hypothesised that the intervention would improve child development over usual care. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173251PMC
October 2018

Health economics and quality of life in a feasibility RCT of paediatric acute appendicitis: a protocol study.

BMJ Paediatr Open 2018 21;2(1):e000347. Epub 2018 Sep 21.

Department of Paediatric Surgery and Urology, Southampton Children's Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Background: Acute appendicitis is one of the most common acute surgical emergencies in children and accounts for an annual cost of approximately £50 million to the National Health Service. Investigating alternative treatment options offers the best prospect of enhancing the quality of care for patients and potential opportunities for cost savings through better allocative efficiency. A feasibility randomised controlled trial (RCT) comparing a non-operative treatment pathway with appendicectomy for children with acute uncomplicated appendicitis is underway (CONTRACT feasibility RCT). Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157565PMC
September 2018

Why data sharing is important for children.

Authors:
Imti Choonara

BMJ Paediatr Open 2018 19;2(1):e000356. Epub 2018 Sep 19.

University of Nottingham School of Medicine, Derby, UK.

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http://bmjpaedsopen.bmj.com/lookup/doi/10.1136/bmjpo-2018-00
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http://dx.doi.org/10.1136/bmjpo-2018-000356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150183PMC
September 2018
4 Reads

Qualitative study investigating the perceptions of parents of children who failed vision screening at the age of 4-5 years.

BMJ Paediatr Open 2018 14;2(1):e000307. Epub 2018 Sep 14.

Department of Health Sciences, University of York, York, UK.

Objective: To explore in depth parents' experiences and understanding of their children's eye care in order to better comprehend why there is relatively low uptake of services and variable adherence to treatment.

Design: Semistructured interviews, informed by the Health Belief framework, were conducted with parents of children who had failed vision screening at age 4-5 years. Four were parents of children who never attended follow-up, 11 had children who attended but did not adhere to spectacle wear and 5 parents of children who had attended and adhered. Read More

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http://dx.doi.org/10.1136/bmjpo-2018-000307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144893PMC
September 2018