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    72641 results match your criteria BMJ Clinical research ed.[Journal]

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    Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes.
    BMJ 2017 Nov 22;359:j5024. Epub 2017 Nov 22.
    Academic Unit of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, South Academic Block, Southampton General Hospital, Southampton, Hampshire SO16 6YD, UK.
    Objectives To evaluate the existing evidence for associations between coffee consumption and multiple health outcomes.Design Umbrella review of the evidence across meta-analyses of observational and interventional studies of coffee consumption and any health outcome.Data sources PubMed, Embase, CINAHL, Cochrane Database of Systematic Reviews, and screening of references. Read More

    Prevalence and clinical profile of microcephaly in South America pre-Zika, 2005-14: prevalence and case-control study.
    BMJ 2017 Nov 21;359:j5018. Epub 2017 Nov 21.
    National Institute of Population Medical Genetics (INAGEMP), Porto Alegre, Brazil.
    Objective To describe the prevalence and clinical spectrum of microcephaly in South America for the period 2005-14, before the start of the Zika epidemic in 2015, as a baseline for future surveillance as the Zika epidemic spreads and as other infectious causes may emerge in future.Design Prevalence and case-control study.Data sources ECLAMC (Latin American Collaborative Study of Congenital Malformations) database derived from 107 hospitals in 10 South American countries, 2005 to 2014. Read More

    Development and validation of QDiabetes-2018 risk prediction algorithm to estimate future risk of type 2 diabetes: cohort study.
    BMJ 2017 Nov 20;359:j5019. Epub 2017 Nov 20.
    Division of Primary Care, University of Nottingham, Nottingham NG2 7RD, UK.
    Objectives To derive and validate updated QDiabetes-2018 prediction algorithms to estimate the 10 year risk of type 2 diabetes in men and women, taking account of potential new risk factors, and to compare their performance with current approaches.Design Prospective open cohort study.Setting Routinely collected data from 1457 general practices in England contributing to the QResearch database: 1094 were used to develop the scores and a separate set of 363 were used to validate the scores. Read More

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