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    15302 results match your criteria BMJ Case Reports [Journal]

    1 OF 307

    Cervical oesophageal perforation secondary to food consumption in a well-appearing patient.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
    A 71-year-old woman presented to the emergency department 8 days after ingesting fish with mild neck pain but otherwise demonstrated no signs of infection. X-rays were negative but CT imaging demonstrated a curvilinear radiodense object extending from the posterior cervical oesophagus through the right thyroid lobe terminating in the neck just a few millimetres from the external carotid artery. Rigid oesophagoscopy and direct laryngoscopy were negative and the neck was explored for the foreign body, which ultimately was encountered after a painstaking dissection of the right neck that included skeletonisation of the recurrent laryngeal nerve. Read More

    Iatrogenic injury of vertebral artery resulting in stroke after central venous line insertion.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Vascular Surgery, West Coast Vascular, Nedlands, Australia.
    There are many complications of central venous catheter insertion. Iatrogenic injury of the vertebral artery is a rare complication that can result in severe morbidity and mortality. The case presented describes the complication of an acute ischaemic stroke after cannulation of the vertebral artery. Read More

    Concomitant AIDS cholangiopathy and Fanconi syndrome as complications of HIV in a single patient.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Acute Medical Unit, Croydon University Hospital, London, UK.
    We describe the case of a 50-year-old woman presenting to our acute medicine department with generalised non-specific symptoms on a background of HIV managed on triple therapy (tenofovir, lamivudine and zidovudine). On admission, she was noted to be acidotic with proteinuria, glycosuria, hypophosphataemia and generalised body pain, and was diagnosed with Fanconi's renotubular syndrome secondary to tenofovir. It was also noted that she had elevated liver dysfunction markers, and an MRI of the liver revealed a focal stricture near the ampulla of Vater, resulting in a diagnosis of AIDS cholangiopathy. Read More

    5-FU-induced leukoencephalopathy with reversible lesion of splenium of corpus callosum in a patient with colorectal cancer.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Emergency Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
    5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has been approved for treatment of various cancers. Neurotoxicities are considered extremely rare side effects of 5-FU. We present a case of 5-FU-induced encephalopathy with diffusion-restricted reversible lesion of the splenium of the corpus callosum in a patient with colorectal cancer. Read More

    A rare case of dual diagnosis in a 16-year-old girl with shortness of breath.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Emergency Department, West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
    Pneumothorax and pulmonary embolism (PE) are two life-threatening causes of shortness of breath in patients presenting to the emergency department. A rare but more serious presentation is that of simultaneous PE and pneumothorax. We present the case of a young patient, with no known comorbidities, who presented with simultaneous submassive PE and pneumothorax. Read More

    Mid-aortic syndrome secondary to Takayasu's disease.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Radiology, Queen Mary Hospital, Pok Fu Lam, Hong Kong.
    A 24-year-old young woman with good past health presented with hypertension during body check. Blood erythrocyte sedimentary rate level was elevated. CT and MR angiography revealed moderate stenosis of abdominal aorta and bilaterally renal arteries. Read More

    Pushing beyond the limit: a novel clinical sign of thoracic aortic dissection.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Cardiology, St Vincent's Hospital, Sydney, New South Wales, Australia.
    The timely diagnosis of aortic dissection is notoriously confounded by unreliable symptomatology. We present a previously unreported clinical sign: thoracic pain reproduced by abdominal palpation. Our case illustrates the dependence of traditional clinical features on the anatomical location of an aortic dissection and lends weight to the concept of aortic pain as being a dynamic product of inter-related changes in intraluminal pressure, volume, wall stress and diameter. Read More

    Severe panniculitis and polyarthritis caused by acinar cell carcinoma arising from an ectopic pancreas.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Pathology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium.
    The pancreatitis, panniculitis and polyarthritis (PPP) syndrome is a rare condition caused by pancreatic diseases, such as acute or chronic pancreatitis or pancreatic carcinoma. We report the first case of PPP syndrome caused by metastatic acinar cell carcinoma from an ectopic pancreas. The symptoms were successfully managed by the treatment of the metastatic carcinoma. Read More

    Ischaemic pituitary tumour apoplexy and concurrent meningitis: a diagnostic dilemma.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Neurology, Aga Khan University Hospital, Karachi, Pakistan.
    Pituitary tumour apoplexy is a rare but potentially life threatening clinical syndrome that mostly results from haemorrhage in the pre-existent tumour. Pure ischaemic subtype of apoplexy is even rarer. The presentation can be hard to differentiate clinically from bacterial meningitis. Read More

    Hyperacute leucopenia associated with furosemide.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    IPC Healthcare/TeamHealth, Lake Mary, Florida, USA.
    A 72-year-old man presented to the hospital with exacerbation of congestive heart failure. He was given furosemide 40 mg intravenously twice at 4 hours apart. At 4 hours after the second dose of furosemide, his white blood cells (WBC) dropped acutely from 9. Read More

    Out of the blue finger ischaemia and occult colorectal cancer.
    BMJ Case Rep 2017 Mar 8;2017. Epub 2017 Mar 8.
    Hebrew University Faculty of Medicine, Jerusalem, Israel.
    A woman aged 66 years with a history of unprovoked deep venous thrombosis (DVT) presented with persistent digital ischaemic changes of 2 of her right hand fingers. Physical examination was otherwise normal and extensive laboratory and imaging studies were unremarkable. A history of unprovoked DVT and the current episode of digital ischaemia prompted concern for underlying occult malignancy. Read More

    Source estimation of epileptic activity using eLORETA kurtosis analysis.
    BMJ Case Rep 2017 Nov 16;2017. Epub 2017 Nov 16.
    Department of Neuropsychiatry, Kansai Medical University,, Osaka, Japan.
    Exact low-resolution brain electromagnetic tomography (eLORETA) is a technique for three-dimensional representation of the distribution of sources of electrical activity in the brain. Kurtosis analysis allows for identification of spiky activity in the brain. To evaluate the reliability of eLORETA kurtosis analysis, the results of the analysis were compared with those of equivalent current dipole (ECD) and synthetic aperture magnetometry (SAM) kurtosis analysis of magnetoencephalography (MEG) data in a patient with epilepsy with elementary visual seizures in a 6-year follow-up. Read More

    Primary intraventricular haemorrhage due to rupture of giant varix of the basal vein of Rosenthal in a patient with long-standing direct CCF: angiographic features and treatment considerations.
    BMJ Case Rep 2017 Nov 16;2017. Epub 2017 Nov 16.
    Imaging Sciences & Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
    Direct carotid cavernous fistulae (CCF) are often detected early and treated promptly resulting in a paucity of literature regarding its long-term evolution. We present a case of high flow post-traumatic direct CCF that was neglected for over 6 years and presented with a rare manifestation of primary intraventricular haemorrhage. Occlusions of the primary venous outlets likely resulted in engorgement of the deep venous system. Read More

    Endovascular rescue treatment through stent positioning after surgical clipping of intracranial aneurysms complicated by parent artery obstruction.
    BMJ Case Rep 2017 Nov 16;2017. Epub 2017 Nov 16.
    Neuroradiology Unit, Padua University Hospital, Padua, Veneto, Italy.
    During aneurysm clipping, ischemic complications may occur and require a rescue treatment, usually surgical. We present two such cases that required urgent rescue treatment, performed through an endovascular route. Our first case presented with a non-ruptured right posterior inferior cerebellar artery (PICA) aneurysm. Read More

    Rare cause of adrenal insufficiency.
    BMJ Case Rep 2017 Nov 16;2017. Epub 2017 Nov 16.
    Department of Geriatrics and General Medicine, St John of God Hospital, Subiaco, Western Australia, Australia.
    A 72-year-old man presented with weight loss, night sweats and haemoptysis and was hypotensive. CT imaging showed rapidly enlarging bilateral adrenal masses, and he was found to have primary adrenal insufficiency. An adrenal gland biopsy revealed the rare diagnosis of primary adrenal lymphoma. Read More

    Umbilical artery perforation: a potentially life-threatening complication of umbilical artery catheterisation.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Department of Neonatology, VU University Medical Center, Amsterdam, The Netherlands.
    Umbilical artery catheterisation is frequently performed in preterm or critically ill newborn infants for invasive monitoring of blood pressure and blood sampling for laboratory tests. It is associated with well-known complications like catheter-related infections, thromboembolic events and aneurysmal formation of the aorta. In this report, we present another major complication of umbilical artery catheterisation: umbilical artery perforation. Read More

    Norethisterone enanthate-induced cerebral venous sinus thrombosis (CVST).
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Department of Medicine, South West Regional Health Authority, San Fernando, Trinidad and Tobago.
    A 23-year-old East Indian woman with no significant medical history, except a depot-norethisterone enanthate injection taken 3 weeks prior to admission, presented with a gradually worsening headache for the past 5 days. She had no fever, vomiting, neck stiffness, focal weakness or rash, and examination was unremarkable with no focal neurological deficits. Vasculitic, thrombophilia and sepsis screens were normal. Read More

    Septic arthritis of knee joint due to Parvimonas micra.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.
    Parvimonas species are anaerobic, Gram-positive cocci that are a constituent of normal oral and gastrointestinal flora. We present a case of right knee joint septic arthritis due to Parvimonas micra in an immunocompromised patient. A 61-year-old male renal and pancreatic transplant recipient on immunosuppressive therapy was admitted to our hospital due to intense pain, joint swelling and inability to move his right knee over the past 9 months. Read More

    Reversible brain lesion following growth hormone replacement therapy in an adolescent.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Department of Pediatrics, National and Kapodistrian University of Athens, Athens, Greece.
    A 12.6-year-old girl presented with a 2-month history of headache, recurrent vomiting and 5 kg weight loss. She had been receiving recombinant human growth hormone (rhGH) replacement therapy at a dose of 0. Read More

    Ectopic ACTH syndrome complicated by multiple opportunistic infections treated with percutaneous ablation of the adrenal glands.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Department of Medicine, University of British Columbia, Vancouver, Canada.
    Ectopic adrenocorticotropic hormone (ACTH)-related Cushing's syndrome can lead to multiple complications including severe immunosuppression. If the ACTH-secreting tumour cannot be found, definitive treatment is surgical adrenalectomy, typically followed by glucocorticoid replacement. Here, we present a case of fulminant respiratory failure secondary to coinfection with Pneumocystis jirovecii and cytomegalovirus in a patient with ectopic ACTH-dependent Cushing's syndrome with occult primary. Read More

    Unusual Salmonella typhi periprosthetic joint infection involving bilateral knees: management options and literature review.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Department of Microbiology, Fortis Escorts Heart Institute, New Delhi, Delhi, India.
    A 70-year-old Indian woman, who had undergone primary bilateral total knee arthroplasty (TKA) for rheumatoid arthritis 10 months prior, presented with 10 days history of pain, swelling and erythema over both knees with pus discharging from the right knee. She had type 2 diabetes mellitus and was on long-term steroid, leflunomide and antitumour necrosis factor therapy for rheumatoid arthritis. Her clinical and laboratory features were suggestive of a haematogenous periprosthetic joint infection (PJI). Read More

    Antenatal Bartter syndrome presenting with vomiting and constipation mimicking subacute intestinal obstruction in a 20-day-old neonate.
    BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.
    Hamad Medical Corporation, Doha, Qatar.
    Antenatal Bartter syndrome is a rare condition that can present with different clinical features. These features include early onset maternal polyhydramnios, failure to thrive, prematurity and nephrocalcinosis.We are presenting this 20-day-old girl who had an antenatal history of polyhydramnios. Read More

    Successful downstaging of locally recurrent penile squamous cell carcinoma with neoadjuvant nanosomal docetaxel lipid suspension (NDLS) based regimen followed by curative surgery.
    BMJ Case Rep 2017 Nov 12;2017. Epub 2017 Nov 12.
    Department of Medical Affairs and Clinical Research, Intas Pharmaceuticals Limited, Ahmedabad, India.
    Penile squamous cell carcinoma (pSCC) is a relatively rare disease in Western world but is a significant health problem in developing countries like India. We report here a case of successful multimodality management of recurrent pSCC with pelvic lymphadenopathy in a 56-year-old male patient with poorly controlled diabetes. The patient presented with ulceroproliferative growth over the residual penile stump clinically involving root of penis and with right pelvic lymphadenopathy. Read More

    Tubular sigmoid duplication in an adult man: an interesting incidental finding.
    BMJ Case Rep 2017 Nov 12;2017. Epub 2017 Nov 12.
    Colorectal Surgery, BHR University Hospitals NHS Trust, Queen's Hospital, Romford, UK.
    A 61-year-old man attended an outpatient colorectal clinic for a chronic, non-specific abdominal pain, associated with rectal bleeding. He underwent a number of investigations including a CT pneumocolon, which revealed an incidental finding of 20 cm of additional sigmoid colon. This case is interesting because tubular sigmoid duplication is an extremely unusual condition, rarely diagnosed in adults; only a few cases have been reported of this condition in the adult population. Read More

    Orlistat-induced oxalate nephropathy: an under-recognised cause of chronic kidney disease.
    BMJ Case Rep 2017 Nov 12;2017. Epub 2017 Nov 12.
    Department of Histopathology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
    Two patients developed kidney failure due to oxalate deposition in the kidney while taking orlistat. Cessation of orlistat was followed by partial recovery of kidney function. The mechanism by which orlistat causes hyperoxaluria and the management of orlistat-induced oxalate nephropathy is reviewed. Read More

    Tuberculosis epididymitis complicated by a cutaneous fistula.
    BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.
    Department of Surgery, Alta Bates Summit Medical Center, Berkeley, California, USA.
    A 63-year-old man developed scrotal swelling that became bilateral over 2 months. His symptoms persisted after treatment for epididymitis, and he developed a scrotal fistula with drainage. Mycobacterium tuberculosis grew from the urine and fistula. Read More

    Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence.
    BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.
    Department of Chinese Medicine, Taipei City Hospital, Linsen, Chinese Medicine, and Kunming Branch, Taipei, Taiwan.
    This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were observed during the initial stage; therefore, we prescribed a combination of Chaihu-Shugan-San, Zhi Bai Di Huang and Chin-Gin-Kuan-Ming decoction as the major herbal synergic regimen to relieve the symptoms of opioid withdrawal, anxiety and insomnia. Read More

    Radiation retinopathy treated successfully with aflibercept.
    BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.
    Ophthalmology Department, University Hospital Wales, Cardiff, UK.
    Aflibercept (aflibercept) is a novel anti-vascular endothelial growth factor drug indicated for wet age-related macular degeneration and macular oedema secondary to retinal vein occlusion and diabetic macular oedema. While only newly introduced on the market, it is growing in popularity and over 5.5 million doses have been prescribed worldwide. Read More

    Nephrotic syndrome and acute kidney injury induced by malathion toxicity.
    BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.
    Department of Nephrology, Shunan City Shinnanyo Hospital, Shunan, Japan.
    We treated a case of acute kidney injury and nephrotic syndrome after malathion inhalation. A 69-year-old Japanese man presented with oedema 15 days after inhalation of malathion, a widely used pesticide. Serum albumin was 2. Read More

    Eosinophilic oesophagitis and coeliac disease: is there an association?
    BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.
    Gastroenterology Department, Centro Hospitalar do Algarve, Faro, Portugal.
    A 25-year-old man was seen in outpatient clinic for progressive solid food dysphagia. He was already medicated with a proton pump inhibitor with no improvement. His blood tests showed a slight microcytic anaemia and peripheral eosinophilia. Read More

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