18,059 results match your criteria BMJ Case Reports [Journal]


Acute adrenal failure: a potentially fatal consequence of an adulterated herbal remedy.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Chemical Pathology, New Cross Hospital, Wolverhampton, UK.

Herbal remedies adulterated with glucocorticoids can cause Cushing's syndrome. We report a severe presentation of a 'herbal remedy' adulterated with glucocorticoids; causing a potentially fatal adrenal crisis precipitated by acute illness. Investigations were consistent with adrenal suppression and confirmed, after tablet analysis, to be due to a 'herbal remedy' containing synthetic betamethasone/dexamethasone. Read More

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http://dx.doi.org/10.1136/bcr-2018-228443DOI Listing
February 2019

Left main coronary artery diverticulae: a rare case.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Department of Cardiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

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http://dx.doi.org/10.1136/bcr-2019-229214DOI Listing
February 2019

Calcium management challenges in a macrosomic child with subcutaneous fat necrosis.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Paediatric Dermatology, KK Women's and Children's Hospital, Singapore.

We present a case that illustrates the fluctuations in calcium levels to be expected while managing an infant with maternal gestational diabetes mellitus who also develops subcutaneous fat necrosis (SCFN). There is initial hypocalcaemia due to functional hypoparathyroidism, requiring judicious calcium replacement. But with increased extrarenal production of 1,25-dihydroxyvitamin D due to granulomatous inflammation of subcutaneous adipose tissue, hypercalcaemia ensues. Read More

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http://dx.doi.org/10.1136/bcr-2018-227141DOI Listing
February 2019

Atypical testicular pain.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Urological Surgery, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Frimley, UK.

Testicular tuberculosis (TB) is rare, and, because of this, the lack of pathognomonic clinical features and its tendency to mimic other commoner conditions, the diagnosis is frequently delayed or may be missed. In this case, the initial clinical presentation was typical for bacterial epididymo-orchitis in a 38-year-old man. When the patient failed to improve with standard treatment including broadening of antibiotics, the diagnosis was re-considered because some unusual signs suggested testicular malignancy or lymphoma. Read More

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http://dx.doi.org/10.1136/bcr-2018-226697DOI Listing
February 2019

complex infection mimicking lung cancer.

Authors:
Hideharu Hagiya

BMJ Case Rep 2019 Feb 18;12(2). Epub 2019 Feb 18.

Department of General Internal Medicine, Osaka University Hospital, Suita, Osaka, Japan.

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http://dx.doi.org/10.1136/bcr-2018-228847DOI Listing
February 2019

Hyperferritinaemia following intrauterine transfusions for Rh isoimmunisation.

BMJ Case Rep 2019 Feb 18;12(2). Epub 2019 Feb 18.

Neonatology Unit, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Intrauterine transfusion is one of the mainstays of treatment in isoimmunised pregnancies guided by the changes in middle cerebral artery Doppler of the fetus. The common postnatal complications associated with Rh isoimmunisation are high unconjugated bilirubin requiring blood exchange transfusions, cholestasis due to bile inspissation, thrombocytopenia and anaemia. Hyperferritinaemia is an uncommon adverse effect observed in Rh isoimmunised pregnancies. Read More

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http://dx.doi.org/10.1136/bcr-2018-227225DOI Listing
February 2019

XCalibur aneurysm occlusion device for the treatment of direct carotid cavernous fistula: expansion of armamentarium.

BMJ Case Rep 2019 Feb 18;12(2). Epub 2019 Feb 18.

Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

We report the first case of a post-traumatic direct carotid cavernous fistula (CCF) treated with the XCalibur aneurysm occlusion device, which is a balloon mounted stent with flow diversion effect. Two devices were deployed across the fistula in an overlapping manner, resulting in complete occlusion of the fistula. Flow diversion with this device can provide a safe and alternative treatment option in direct CCF. Read More

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http://dx.doi.org/10.1136/bcr-2018-014475DOI Listing
February 2019

Liver transplant, toxoplasmosis and kidney stones: connecting the dots.

BMJ Case Rep 2019 Feb 15;12(2). Epub 2019 Feb 15.

Department of Nephrology, University of Florida College of Medicine, Gainesville, Florida, USA.

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http://dx.doi.org/10.1136/bcr-2019-229197DOI Listing
February 2019
1 Read

Methemoglobinaemia with chronic phenazopyridine ingestion.

BMJ Case Rep 2019 Feb 15;12(2). Epub 2019 Feb 15.

Emergency Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1136/bcr-2018-227538DOI Listing
February 2019

rearranged acute lymphoblastic leukaemia presenting as a maxillary sinus mass with a discordant immunophenotypic profile from the bone marrow.

BMJ Case Rep 2019 Feb 15;12(2). Epub 2019 Feb 15.

Department of Pediatric Hematology-Oncology, University of California San Diego, San Diego, California, USA.

We describe an unusual case of pre-B lymphoblastic leukaemia presenting with a unilateral maxillary sinus mass in which biopsies of the primary mass and the bone marrow demonstrated conflicting immunophenotyping results. The extramedullary mass was consistent with a precursor B-cell malignancy, while the bone marrow was initially reported as a possible mature B-cell malignancy. The treatments for the two are fundamentally different, which necessitated a delay in the initiation of his chemotherapy until a clear diagnosis was made. Read More

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http://dx.doi.org/10.1136/bcr-2018-227400DOI Listing
February 2019
1 Read

Spinal epidural lipomatosis following bilateral spinal decompression surgery.

BMJ Case Rep 2019 Feb 15;12(2). Epub 2019 Feb 15.

North Bristol NHS Trust, Bristol, UK.

A 73-year-old man underwent bilateral spinal decompression of L4/5 for severe spinal canal stenosis, requiring minimal analgesia and providing immediate relief. Two days post-operatively, he presented with new onset bilateral leg pain and difficulty mobilising. MRI demonstrated spinal epidural lipomatosis (SEL), which was not present pre-operatively, at L5/S1. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22698
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http://dx.doi.org/10.1136/bcr-2018-226985DOI Listing
February 2019
2 Reads

Neuroblastoma with an unusual ovarian metastasis in a 5-year-old girl.

BMJ Case Rep 2019 Feb 15;12(2). Epub 2019 Feb 15.

Department of Paediatric Surgery, Noah's Ark Children's Hospital, University Hospital of Wales, Cardiff, UK.

Neuroblastoma metastasizing to the ovary is rare. We report the 10th case and review the scarce literature. A 5-year-old girl with stage M neuroblastoma presented with an upper abdominal and a pelvic mass. Read More

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http://dx.doi.org/10.1136/bcr-2018-226038DOI Listing
February 2019

Concealed diagnosis of duodenal perforation in a patient with emphysematous pyelonephritis: the dilemma of air in the right perirenal space.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.1136/bcr-2018-228629DOI Listing
February 2019
1 Read

Dopamine agonist-responsive Cushing's disease.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Endocrinology, University Hospital Zürich, Zürich, Switzerland.

A 47-year-old Caucasian man was referred to our clinic with a severe clinical and biochemical phenotype of endogenous hypercortisolism for further evaluation and treatment. In addition to confirming adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome, we found left temporal hemianopsia, massively increased prolactin, increased growth hormone/insulin-like growth factor 1 values, hypogonadotropic hypogonadism and central hypothyroidism. As the cause of these abnormalities we revealed an invasive macroadenoma of the pituitary secreting ACTH, prolactin and growth hormone, resulting not only in a clinically predominant picture of Cushing's syndrome but also causing hypogonadotropic hypogonadism and central hypothyroidism. Read More

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http://dx.doi.org/10.1136/bcr-2018-228045DOI Listing
February 2019
6 Reads

Bilateral osteonecrosis of the hip in panhypopituitarism.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Osteonecrosis, also known as avascular necrosis, is a condition that causes significant morbidity and loss of function. It is a common complication seen with supraphysiological steroid use. Early diagnosis is critical as it impacts prognosis. Read More

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http://dx.doi.org/10.1136/bcr-2018-227471DOI Listing
February 2019
9 Reads

Fitz-Hugh-Curtis syndrome.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of General Medicine, Chiba University Hospital, Chiba, Japan.

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http://dx.doi.org/10.1136/bcr-2019-229326DOI Listing
February 2019
1 Read

Diffuse plane xanthoma developing in association with prior monoclonal gammopathy.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Dermatology, Stadtisches Klinikum Muenchen GmbH, Muenchen, Germany.

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http://dx.doi.org/10.1136/bcr-2018-229164DOI Listing
February 2019

Biceps tendon rupture associated with ciprofloxacin use for spontaneous bacterial peritonitis prophylaxis.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Internal Medicine, Sparrow Hospital, Lansing, Michigan, USA.

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http://dx.doi.org/10.1136/bcr-2018-229116DOI Listing
February 2019

Atypical anaplastic astrocytoma with unique molecular features and diffuse leptomeningeal spread in a child with long-term survival.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Neurosciences and Pediatrics, University of California San Diego, San Diego, California, USA.

Paediatric high-grade gliomas, including glioblastoma and anaplastic astrocytoma, make up 8%-12% of paediatric central nervous system tumours and have poor prognosis, with 2-year survival less than 30% and overall survival less than 10%. The only known prognostic factors in this population include extent of resection and tumour histological grade. We present the case of a 9-year-old boy with disseminated anaplastic astrocytoma treated with subtotal resection, craniospinal radiation and temozolomide, with 8-year survival despite metastatic disease at presentation and subtotal resection. Read More

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http://dx.doi.org/10.1136/bcr-2018-228153DOI Listing
February 2019
1 Read

Spontaneous cholecystocutaneous fistula: empirically treated for a missed diagnosis, managed by laparoscopy.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

A 70-year-old woman was referred to our hospital from primary health centre with complaints of pain in the abdomen, swelling and discharging sinus in the right hypochondrium since 2 years. She had received anti-tubercular treatment for 18 months as the wedge biopsy of the sinus tract suggested granulomatous lesion. As the symptoms did not subside she was referred to our hospital. Read More

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http://dx.doi.org/10.1136/bcr-2018-228138DOI Listing
February 2019
1 Read

Laparoscopic management of epidermoid cyst in an unusual location.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Minimally Invasive and G.I. Surgery, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India.

The pararectal space or presacral space is a potential site for various cysts and tumours because it consists of many types of embryonic tissues. Although epidermoid cyst is a well-known entity, encountering a pararectal epidermoid cyst is relatively rare. The incidence of cystic tumours in the pararectal space has been reported to be 1 in 40 000 to 63 000 patients. Read More

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http://dx.doi.org/10.1136/bcr-2018-228043DOI Listing
February 2019

Spontaneous simultaneous bilateral patellar tendon rupture.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Emergency Medicine, Sligo University Hospital, Sligo, Ireland.

Bilateral patellar tendon rupture is an extremely rare occurrence, especially in otherwise healthy individuals without systemic disease. The authors report the case of a man who presented with simultaneous, spontaneous bilateral rupture of his patellar tendons. He had a history of unilateral patellar tendinopathy but no other predisposing risk factors such as steroid or fluoroquinolone use. Read More

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http://dx.doi.org/10.1136/bcr-2018-227931DOI Listing
February 2019
2 Reads

Allergic bronchopulmonary aspergillosis presumably unmasked by PD-1 inhibition.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Pulmonary and Critical Care, Tower Health System, West Reading, Pennsylvania, USA.

Programmed cell death-1 (PD-1) inhibitors stimulate immune recognition of tumour cells in cancer patients, but have significant autoimmune side effects including pneumonitis. We report the case of a patient with asthma and mild eosinophilia who developed unusual pulmonary side effect of bronchiectasis, severe eosinophilia (absolute eosinophil count: 3200 c/mm) and elevated IgE levels (7050 IU/mL; normal: <164 IU/mL) 4 months into therapy with the PD-1 inhibitor pembrolizumab. Aspergillus fumigatus IgG was elevated at 15. Read More

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http://dx.doi.org/10.1136/bcr-2018-227814DOI Listing
February 2019
1 Read

Nitrous oxide myelopathy with functional vitamin B deficiency.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Neurology, The Walton Centre Foundation NHS Trust, Liverpool, UK.

Recreational use of nitrous oxide as a 'legal high' is increasing in the UK. Physicians should be 'street wise' to this increasing prevalence and aware of the potential neurological complications which may result from misuse. We describe a 17-year-old male patient who presented to neurology with a severe myelopathy following prolonged recreational use of nitrous oxide. Read More

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http://dx.doi.org/10.1136/bcr-2018-227439DOI Listing
February 2019

Unusual presentation of acute pancreatitis following high tibial osteotomy.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of General Surgery, Royal Albert Edward Infirmary, Wigan, UK.

We report a case of a 55-year-old man taxi driver admitted electively for high tibial osteotomy for relief of bilateral medial compartment osteoarthritis. He was obese and an ex-smoker but medical history was otherwise unremarkable. Day 1 postoperatively the patient started to suffer vomiting episodes and the abdomen was distended. Read More

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http://dx.doi.org/10.1136/bcr-2018-227438DOI Listing
February 2019
1 Read

Morvan's syndrome treated successfully with rituximab and lacosamide.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.

We describe a woman with both central and peripheral nervous system symptoms consistent with Morvan's syndrome who was successfully treated with immunosuppression including rituximab and the new antiepileptic drug lacosamide against peripheral nerve hyperexcitability. Despite being over 8 months in hospital and 4 months in an intensive care unit she recovered fully. It is also the first case where cerebrospinal fluid neurofilament-light (NfL) levels were followed during the disease course. Read More

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http://dx.doi.org/10.1136/bcr-2018-226832DOI Listing
February 2019
2 Reads

Spontaneous pneumomediastinum and subcutaneous emphysema in a child with unknown aetiology.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Paediatrics, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, Bedfordshire, UK.

Spontaneous subcutaneous emphysema and pneumomediastinum in children without any predisposing factors is a rare entity. We present a case of an adolescent boy with spontaneous pneumomediastinum. He is a 14-year-old boy brought to the hospital with an odd feeling in the neck and chest. Read More

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http://dx.doi.org/10.1136/bcr-2018-226805DOI Listing
February 2019
1 Read

Ergometrine-induced atrial fibrillation at caesarean section.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Centenary Hospital for Women and Children, Canberra Hospital, Garran, Australian Capital Territory, Australia.

A 36-year-old woman with a history of one previous caesarean section presented to the birthing suite of a regional hospital with spontaneous rupture of membranes at 39+2/40 weeks. Syntocinon was administered to initiate uterine contractions in the absence of labour, as the patient desired vaginal birth. A caesarean section was subsequently indicated and ergometrine was administered for uterine atony. Read More

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http://dx.doi.org/10.1136/bcr-2018-226747DOI Listing
February 2019
2 Reads

Visceral leishmaniasis with haemophagocytic lymphohistiocytosis.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of General Medicine, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

A 27-year-old man presented with high-grade intermittent fever for 4 months, generalised fatigue for 2 months, intermittent gum bleeds for 1 month and loss of weight of 15 kg. He appeared cachectic with generalised wasting, had pallor and features of reticuloendothelial system proliferation. His liver span was 17 cm. Read More

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http://dx.doi.org/10.1136/bcr-2018-226361DOI Listing
February 2019
1 Read

Spontaneous pneumomediastinum complicating asthma exacerbation.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, Illinois, USA.

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http://dx.doi.org/10.1136/bcr-2018-229118DOI Listing
February 2019
1 Read

Unexpected extremity injury in orthopaedic emergency service.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Orthopaedics and Traumatology, Duzce Universitesi, Duzce, Turkey.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22856
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http://dx.doi.org/10.1136/bcr-2018-228566DOI Listing
February 2019
3 Reads

When a bruise gets important: Bednar tumour.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Dermatovenereology, Hospital de Braga, Braga, Portugal.

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http://dx.doi.org/10.1136/bcr-2018-228446DOI Listing
February 2019
1 Read

Gas-forming gluteal abscess after intramuscular self-injections due to .

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Spain.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22840
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http://dx.doi.org/10.1136/bcr-2018-228408DOI Listing
February 2019
3 Reads

Disseminated CMV infection and HLH in a patient with well-controlled HIV and ulcerative colitis.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Genitourinary Medicine and HIV, Imperial College Healthcare NHS Trust, London, UK.

We present a case of haemophagocytic lymphohistiocytosis (HLH) in the context of disseminated cytomegalovirus (CMV) viraemia in a 50-year-old man with well-controlled HIV infection and ulcerative colitis (UC), for which he was receiving azathioprine. Peak CMV viral load was 371 000 copies/ml with evidence of end-organ CMV in the lungs and colon. A bone marrow biopsy showed evidence of haemophagocytosis of platelets, neutrophils and erythrocytes. Read More

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http://dx.doi.org/10.1136/bcr-2018-227916DOI Listing
February 2019
1 Read

Anorexia nervosa presenting as diffuse spontaneous air leaks.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Manchester Medical School, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/bcr-2018-227838DOI Listing
February 2019
2 Reads

Canalicular laceration visualisation using chandelier illumination.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.

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http://dx.doi.org/10.1136/bcr-2018-227798DOI Listing
February 2019
1 Read

Rare variant of internal carotid artery anatomy.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1136/bcr-2018-227595DOI Listing
February 2019
1 Read

One aneurysm and two pseudoaneurysms, same patient.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Cardiothoracic Surgery - Hospital de Santa Marta, Centro Hospitalar de Lisboa Central EPE, Lisboa, Lisboa, Portugal.

Ventricular pseudoaneurysms are rare pathological entities that mainly arise in the context of myocardial infarction or post-cardiac surgery. The clinical presentation is usually non-specific, and at times patients are asymptomatic. Mortality is high even with timely surgical intervention. Read More

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http://dx.doi.org/10.1136/bcr-2018-227566DOI Listing
February 2019
1 Read

'When you hear hooves, think zebras, not horses'; two challenging cases of interstitial lung disease (ILD).

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Respiratory Medicine, St Vincent's University Hospital, Dublin, Ireland.

Our case series describes two siblings with complex fibrosing lung diseases. The first patient was initially given a diagnosis of sarcoidosis based on imaging and exclusion of alternative diagnoses. A number of years after diagnosis, he had rapid deterioration of his disease and following surgical lung biopsy, his lung fibrosis was re-classified as chronic hypersensitivity pneumonitis (cHP) with a usual interstitial pneumonia pattern. Read More

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http://dx.doi.org/10.1136/bcr-2018-224507DOI Listing
February 2019
2 Reads

Hydrochlorothizide-induced acute generalised exanthematous pustulosis presenting with bilateral periorbital impetigo.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Ascension Providence Hospital, Southfield, Michigan, USA.

Acute generalised exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterised by the appearance of erythematous plaques and papules with overlying non-follicular pinpoint pustules. Drugs are the cause of AGEP in approximately 90% of cases. The most common causes include anti-infective agents (aminopenicillins, quinolones, antibacterial sulfonamides and terbinafine), antimalarials and diltiazem. Read More

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http://dx.doi.org/10.1136/bcr-2017-223528DOI Listing
February 2019

Posterior reversible encephalopathy syndrome due to hypercalcaemia: a rare cause.

BMJ Case Rep 2019 Feb 11;12(2). Epub 2019 Feb 11.

Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological entity described by Hinchey in late 90's, characterised by variable associations of seizure activity, consciousness impairment ranging from confusion to coma, headaches, visual abnormalities, nausea/vomiting and focal neurological signs. Common causes are accelerated hypertension, eclampsia, preeclampsia, cytotoxic drug use and autoimmune diseases like systemic lupus erythematosus.We report a case of PRES in a 62-year-old female patient due to hypercalcemia secondary to vitamin D toxicity on treatment with calcium supplements and vitamin D for secondary hypoparathyroidism. Read More

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http://dx.doi.org/10.1136/bcr-2017-223415DOI Listing
February 2019
3 Reads

Extranodal diffuse large B cell lymphoma of maxillary sinus presenting as a palatal ulcer.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Department of Oral Surgery, Amrita School of Dentistry, AIMS Campus, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

A multitude of disease processes ranging from periodontitis to malignancies can lead to formation of solitary ulcer on the palate. Hence solitary ulcers of palate can often be a challenging one to diagnose. We report an interesting case of a diffuse large B cell lymphoma of the maxillary sinus which perforated the palatal bone and presented clinically as a palatal ulcer. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22860
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http://dx.doi.org/10.1136/bcr-2018-228605DOI Listing
February 2019
3 Reads

Endonasal marsupialisation of a congenital intranasal nasolacrimal duct cyst.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Otorhinolaryngology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, Japan.

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http://dx.doi.org/10.1136/bcr-2018-228284DOI Listing
February 2019

poisoning: a case report of intentional poisoning.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Neurology, Vinayaka Neuro Multispecialty Clinic, Warangal, India.

We report a case of 50-year-old male patient from tribal area in South Indian state of Telangana, who ingested the liquid extract from crushed leaves of the plant, cleistanthus collinius with the intention of self-harm. Immediate gastric lavage and activated charcoal administration was done and the patient was subsequently admitted into an acute medical care unit. During first 24 hours of monitoring, the patient was clinically stable. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22819
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http://dx.doi.org/10.1136/bcr-2018-228197DOI Listing
February 2019
5 Reads

A case of panitumumab containing chemotherapy causing interstitial lung disease: early recognition and treatment resulting in a good outcome.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Department of Hematology/Oncology, Presence Saint Joseph Hospital Chicago, Chicago, Illinois, USA.

Panitumumab is a recombinant human IgG monoclonal antibody which is used for the treatment of patients with metastatic colorectal cancer (mCRC) with disease progression on or following FOLFIRI (fluoropyrimidine, oxaliplatin and irinotecan) containing chemotherapy regimen. We report a case of an 83-year-old Hispanic man, non-smoker, with KRAS/NRAS wild-type mCRC of the liver who was treated with 9 cycles of FOLFOX4 (fluorouracil, leucovorin and oxaliplatin) and cetuximab. Follow-up abdominal imaging showed progression of CRC, requiring initiation of panitumumab in addition to FOLFIRI. Read More

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http://dx.doi.org/10.1136/bcr-2018-227785DOI Listing
February 2019
1 Read

Rib fracture fixation as a tool for extubation in a resource-poor environment.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Department of General Surgery, Ngwelezana Hospital, Empangeni, KwaZulu Natal, South Africa.

An elderly female with multiple comorbidities was involved in a pedestrian vehicle accident and sustained blunt chest trauma, arriving at a resource-poor hospital in rural South Africa. She had multiple bilateral rib fractures with a unilateral flail segment that caused her to develop respiratory failure. She was intubated and sent to the intensive care unit (ICU) for ventilation. Read More

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http://dx.doi.org/10.1136/bcr-2018-227518DOI Listing
February 2019
1 Read

Bilateral adrenal myelolipomas presenting as acute adrenal insufficiency in an adult with congenital adrenal hyperplasia.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Department of Internal Medicine, division of Endocrinology, Texas Tech University Health Sciences Centre School of Medicine, Lubbock, Texas, USA.

Adrenal myelolipomas are relatively rare tumours composed of adipocytes and myeloid cells that arise in response to chronic adrenocorticotropic hormone stimulation. We present the case of bilateral adrenal myelolipomas in a 39-year-old man with untreated congenital adrenal hyperplasia (CAH) presenting with acute adrenal insufficiency and severe virilisation. Phenotypically, he is a man of short stature and has hyperpigmentation of the skin, gingiva and nail beds. Read More

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http://dx.doi.org/10.1136/bcr-2018-226826DOI Listing
February 2019
2 Reads

Solitary ascending colon ulcer diagnosed as gastrointestinal CMV disease.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Gastroenterology, University of Florida College of Medicine, Gainesville, Florida, USA.

A 42-year-old woman with a history of cholangiocarcinoma on adjuvant chemotherapy with capecitabine presented with painless haematochezia. She was found to have an isolated twenty-five mm ulcer in the ascending colon. Biopsies of the ulceration demonstrated typical cytomegalovirus (CMV) inclusions and her peripheral blood CMV PCR was significantly elevated. Read More

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http://dx.doi.org/10.1136/bcr-2018-226355DOI Listing
February 2019
2 Reads

Pulmonary arteriovenous malformation in hereditary haemorrhagic telangiectasia.

BMJ Case Rep 2019 Feb 9;12(2). Epub 2019 Feb 9.

Centro Hospitalar Barreiro Montijo EPE, Barreiro, Portugal.

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http://dx.doi.org/10.1136/bcr-2018-228456DOI Listing
February 2019
1 Read