186,282 results match your criteria BMC women\'s health[Journal]


Comparison of Treatment Options for Refractory Opioid Use Disorder in the United States and Canada: a Narrative Review.

J Gen Intern Med 2020 May 27. Epub 2020 May 27.

Grayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.

Amidst the opioid overdose crisis, there are increased efforts to expand access to medications for opioid use disorder (MOUD). Hospitalization for the complications of substance use in the United States (US) provides an opportunity to initiate methadone, buprenorphine, and extended release naltrexone and link high-risk, not otherwise engaged, patients into outpatient care. However, treatment options for patients are quickly exhausted when these medications are not desired, tolerated, or beneficial. Read More

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http://dx.doi.org/10.1007/s11606-020-05920-0DOI Listing

Hepatic steatosis is associated with abnormal hepatic enzymes, visceral adiposity, altered myocardial glucose uptake measured by F-FDG PET/CT.

BMC Endocr Disord 2020 May 27;20(1):75. Epub 2020 May 27.

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, Jiangsu, China.

Background: Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease that affects the liver and a variety of extra-hepatic organ systems. This study aimed to investigate the relationship between hepatic steatosis and glucose metabolism in liver and extra-hepatic tissues and organs.

Methods: The whole body F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) images of 191 asymptomatic tumor screening patients were retrospectively analyzed. Read More

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http://dx.doi.org/10.1186/s12902-020-00556-xDOI Listing

Associations between objective measures of physical activity, sleep and stress levels among preschool children.

BMC Pediatr 2020 May 27;20(1):258. Epub 2020 May 27.

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark.

Background: Cortisol is often used as a biological marker for stress. When measured in urine or serum, representing a short-term measurement of the hormone, it has been associated with unfavorable sleep characteristics and both low and high physical activity levels. However, cortisol in hair represents a long-term stress measure and has been suggested as a promising new marker for chronic stress. Read More

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http://dx.doi.org/10.1186/s12887-020-02108-7DOI Listing

Expression patterns of SLIT/ROBO mRNAs reveal a characteristic feature in the entorhinal-hippocampal area of macaque monkeys.

BMC Res Notes 2020 May 27;13(1):262. Epub 2020 May 27.

Division of Brain Biology, National Institute for Basic Biology, 38 Nishigonaka Myodaiji, Okazaki, 444-8585, Japan.

Objective: SLITs are secreted glycoproteins that bind to Roundabouts (ROBOs) which are a family member of transmembrane receptors. SLIT signaling has well-conserved roles in mediating axon repulsion in a developing nervous system. We previously reported that SLIT1 mRNA is enriched in middle layers of the prefrontal cortex of macaque monkeys in a developmentally regulated manner. Read More

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http://dx.doi.org/10.1186/s13104-020-05100-7DOI Listing

Therapeutic abortion in Iran: an epidemiologic study of legal abortion in 2 years.

BMC Res Notes 2020 May 27;13(1):261. Epub 2020 May 27.

Legal Medicine Research Center, Iranian Legal Medicine Organization, Tehran, Iran.

Objectives: Unsafe abortion is one of the most important causes of death and disability among mothers in countries where abortion is illegal. These conditions have changed since then. The present study has investigated the cases who were referred to the legal medicine organization to receive abortion permission. Read More

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http://dx.doi.org/10.1186/s13104-020-05098-yDOI Listing

A review of the use of propensity score diagnostics in papers published in high-ranking medical journals.

BMC Med Res Methodol 2020 May 27;20(1):132. Epub 2020 May 27.

Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.

Background: Propensity scores are widely used to deal with confounding bias in medical research. An incorrectly specified propensity score model may lead to residual confounding bias; therefore it is essential to use diagnostics to assess propensity scores in a propensity score analysis. The current use of propensity score diagnostics in the medical literature is unknown. Read More

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http://dx.doi.org/10.1186/s12874-020-00994-0DOI Listing

Diagnosis of COVID-19 in children: the story evolves.

Authors:
R Harwood I Sinha

BMC Med 2020 May 28;18(1):158. Epub 2020 May 28.

Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

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http://dx.doi.org/10.1186/s12916-020-01631-9DOI Listing

Establishing a diagnostic scale of subacute thyroiditis without radioisotope scanning.

BMC Endocr Disord 2020 May 27;20(1):74. Epub 2020 May 27.

Department of Endocrinology, Yuebei People's Hospital, NO. 133 Huimin South Road, Shaoguan, Guangdong Province, China.

Background: Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning.

Methods: The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selected and divided into study group and control group according to whether they were diagnosed as SAT. Read More

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http://dx.doi.org/10.1186/s12902-020-00554-zDOI Listing

Multiplex PCR for identification of two butterfly sister species: Eurema mandarina and Eurema hecabe.

BMC Res Notes 2020 May 27;13(1):260. Epub 2020 May 27.

Graduate School of Horticulture, Chiba University, Matsudo, Chiba, 271-8510, Japan.

Objective: In insects, closely related species are often difficult or impossible to distinguish solely by morphological traits. Mitochondrial DNA (mtDNA) markers are often useful and reliable for distinguishing closely related species. However, useful mtDNA markers can be unavailable, particularly when such species pairs experienced hybrid introgression in the past. Read More

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http://dx.doi.org/10.1186/s13104-020-05093-3DOI Listing

Construct and factorial validity of Neurobehavioral Disorder associated with Prenatal Alcohol Exposure (ND-PAE).

BMC Psychol 2020 May 27;8(1):53. Epub 2020 May 27.

Faculty of Health Sciences, University of Lethbridge, 4401 University Dr W, Lethbridge, Alberta, T1K 3M4, Canada.

Background: ND-PAE, as a condition needing further study, requires validation. Few studies have assessed the validity of ND-PAE with none using a prospective sample.

Methods: Fifty-eight children underwent multidisciplinary FASD assessments and were evaluated for ND-PAE using a prospective, clinical approach. Read More

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http://dx.doi.org/10.1186/s40359-020-00405-5DOI Listing

An observational study of recess quality and physical activity in urban primary schools.

BMC Public Health 2020 May 27;20(1):792. Epub 2020 May 27.

College of Public Health and Human Sciences, School of Social and Behavioral Health Sciences, Oregon State University, Corvallis, Oregon, USA.

Background: To date, there is scant literature that examines the recess context concurrent with, but separate from, levels of physical activity. The primary purpose of the current study was to examine how recess quality impacted physical activity levels, and how this was moderated by gender. A secondary purpose was to examine if differences in children's engagement in activities occurred between recess sessions scored as low- or high- quality. Read More

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http://dx.doi.org/10.1186/s12889-020-08849-5DOI Listing

Risk stratification for prostate cancer management: value of the Cambridge Prognostic Group classification for assessing treatment allocation.

BMC Med 2020 May 28;18(1):114. Epub 2020 May 28.

Academic Urology Group, Department of Surgery, University of Cambridge, Cambridge, UK.

Background: The five-tiered Cambridge Prognostic Group (CPG) classification is a better predictor of prostate cancer-specific mortality than the traditional three-tiered classification (low, intermediate, and high risk). We investigated radical treatment rates according to CPG in men diagnosed with non-metastatic prostate cancer in England between 2014 and 2017.

Methods: Patients diagnosed with non-metastatic prostate cancer were identified from the National Prostate Cancer Audit database. Read More

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http://dx.doi.org/10.1186/s12916-020-01588-9DOI Listing

Prevalence of pneumonia and its associated factors among under-five children in East Africa: a systematic review and meta-analysis.

BMC Pediatr 2020 May 27;20(1):254. Epub 2020 May 27.

Department of Nursing, College of Health Sciences, Woldia University, P.O.Box 400, Woldia, Ethiopia.

Background: Pneumonia is defined as an acute inflammation of the Lungs' parenchymal structure. It is a major public health problem and the leading cause of morbidity and mortality in under-five children especially in developing countries. In 2015, it was estimated that about 102 million cases of pneumonia occurred in under-five children, of which 0. Read More

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http://dx.doi.org/10.1186/s12887-020-02083-zDOI Listing

Moving a neodymium magnet promotes the migration of a magnetic tracer and increases the monitoring counts on the skin surface of sentinel lymph nodes in breast cancer.

BMC Med Imaging 2020 May 27;20(1):58. Epub 2020 May 27.

Department of Integrated Science and Engineering for Sustainable Society, Chuo University, Tokyo, Japan.

Background: We suspected that moving a small neodymium magnet would promote migration of the magnetic tracer to the sentinel lymph node (SLN). Higher monitoring counts on the skin surface before making an incision help us detect SLNs easily and successfully. The present study evaluated the enhancement of the monitoring count on the skin surface in SLN detection based on the magnet movement in a sentinel lymph node biopsy (SNB) using superparamagnetic iron oxide (SPIO) nanoparticles. Read More

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http://dx.doi.org/10.1186/s12880-020-00459-2DOI Listing

A typology of useful evidence: approaches to increase the practical value of intervention research.

BMC Med Res Methodol 2020 May 28;20(1):133. Epub 2020 May 28.

Procome research group, Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet, SE 171 77, Stockholm, Sweden.

Background: Too often, studies of evidence-based interventions (EBIs) in preventive, community, and health care are not sufficiently useful to end users (typically practitioners, patients, policymakers, or other researchers). The ways in which intervention studies are conventionally conducted and reported mean that there is often a shortage of information when an EBI is used in practice. The paper aims to invite the research community to consider ways to optimize not only the trustworthiness but also the research's usefulness in intervention studies. Read More

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http://dx.doi.org/10.1186/s12874-020-00992-2DOI Listing

Theoretical and methodological considerations in evaluating large-scale health information technology change programmes.

BMC Health Serv Res 2020 May 27;20(1):477. Epub 2020 May 27.

Institute for the Study of Science, Technology and Innovation, The University of Edinburgh, Edinburgh, UK.

Background: Attempts to achieve digital transformation across the health service have stimulated increasingly large-scale and more complex change programmes. These encompass a growing range of functions in multiple locations across the system and may take place over extended timeframes. This calls for new approaches to evaluate these programmes. Read More

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http://dx.doi.org/10.1186/s12913-020-05355-7DOI Listing

Thermal effects of monopolar electrosurgery detected by real-time infrared thermography: an experimental appendectomy study.

BMC Surg 2020 May 27;20(1):116. Epub 2020 May 27.

Pirogov Russian National Research Medical University, Ostrovitianov str. 1, Moscow, 117997, Russia.

Background: Monopolar energy (ME) is routinely used in appendectomy. This study aimed to investigate the degree of lateral thermal spread generated by ME and to evaluate the thermal injury sustained by the close-lying tissues.

Methods: Appendectomy with a monopolar Maryland dissector was performed in 8 rabbits (at 30 and 60 W power settings). Read More

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http://dx.doi.org/10.1186/s12893-020-00735-6DOI Listing

Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution.

BMC Biol 2020 May 27;18(1):57. Epub 2020 May 27.

Origins Center, Nijenborgh 7, 9747AG, Groningen, The Netherlands.

Background: Gene duplication events play an important role in the evolution and adaptation of organisms. Duplicated genes can arise through different mechanisms, including whole-genome duplications (WGDs). Recently, WGD was suggested to be an important driver of evolution, also in hexapod animals. Read More

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http://dx.doi.org/10.1186/s12915-020-00789-1DOI Listing

Epidemiological and clinical characteristics of severe hand-foot-and-mouth disease (HFMD) among children: a 6-year population-based study.

BMC Public Health 2020 May 27;20(1):801. Epub 2020 May 27.

Department of Epidemiology and Health Statistics, School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, China.

Background: Hand-foot-and-mouth disease (HFMD) is considered to be self-limited, however, severe HFMD is a deadly threat for children worldwide, therefore, it is essential to define the clinical and epidemiologic characteristics of children with severe HFMD and identify the risk factors of death.

Methods: Between 2013 and 2018, children who diagnosed with severe HFMD from Chongqing, China were enrolled in this population-based study. A total of 459 severe HFMD children cases were identified during the study period, including 415 survivors and 44 fatal cases. Read More

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http://dx.doi.org/10.1186/s12889-020-08961-6DOI Listing

How does the two-child policy affect the sex ratio at birth in China? A cross-sectional study.

BMC Public Health 2020 May 27;20(1):789. Epub 2020 May 27.

Department of Obstetrics and Gynecology, Hebei General Hospital, No. 348 Heping Road, Shijiazhuang, 050051, Hebei, China.

Background: The One-Child Policy led to the imbalance of the sex ratio at birth (SRB) in China. After that, Two-Child Policy was introduced and gradually liberalized at three stages. If both the husband and wife of one couple were the only child of their parents, they were allowed to have two children in policy (BTCP). Read More

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http://dx.doi.org/10.1186/s12889-020-08799-yDOI Listing

Efficacy of whole body vibration therapy on pain and functional ability in people with non-specific low back pain: a systematic review.

BMC Complement Med Ther 2020 May 27;20(1):158. Epub 2020 May 27.

Department of Rehabilitation Medicine, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Background: Whole body vibration (WBV) is currently increasing in popularity as a treatment modality for musculoskeletal disorders and improving health-related quality of life. Recent research has shown that WBV can reduce low back pain and improve the functional abilities for patients, however, optimal frequency and duration of vibration for therapeutic use is unclear. This review was conducted to summarize and determine the efficacy of whole body vibration therapy on individuals with non-specific low back pain (NLBP) and evaluated methodological quality of the included studies. Read More

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http://dx.doi.org/10.1186/s12906-020-02948-xDOI Listing

Prognostic value of systemic inflammatory factors NLR, LMR, PLR and LDH in penile cancer.

BMC Urol 2020 May 27;20(1):57. Epub 2020 May 27.

Department of Urology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, Yunnan, China.

Background: Penile squamous cell carcinoma (PSCC) represents an important public health problem for developing countries. The major prognostic factors in PSCC are pathological subtype, perineural invasion, lymphovascular invasion, depth of invasion and grade, which are hard to obtain precisely before the operation. Besides, micro-metastases will be detected in about 30% of intermediate-risk patients with clinically non-palpable inguinal lymph nodes after inguinal lymph node dissection (ILND). Read More

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http://dx.doi.org/10.1186/s12894-020-00628-zDOI Listing

Assessment of dental arch stability after orthodontic treatment and oral rehabilitation in complete unilateral cleft lip and palate and non-clefts patients using 3D stereophotogrammetry.

BMC Oral Health 2020 May 27;20(1):154. Epub 2020 May 27.

Department of Prosthodontics and Periodontology, Bauru School of Dentistry and Hospital of Rehabilitation of Craniofacial Anomalies, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil.

Background: Although arch stability has been studied in patients without a cleft, evidence for patients with a cleft is sparse. Therefore, we compared the dimensions and stability of dental arches in cleft lip and palate patients and those without a cleft.

Methods: Forty participants, 20 with a complete unilateral cleft lip and palate and 20 non-cleft patients aged from 18 to 30 years, with anterior and/or posterior crossbite and receiving orthodontic treatment were evaluated retrospectively. Read More

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http://dx.doi.org/10.1186/s12903-020-01143-1DOI Listing

Aescin and diosmin each alone or in low dose- combination ameliorate liver damage induced by carbon tetrachloride in rats.

BMC Res Notes 2020 May 27;13(1):259. Epub 2020 May 27.

Biology Department, UAE University, Al Ain, UAE.

Objective: This study evaluated hepatoprotective effect of aescin (AES) and diosmin (DIO), individually or in low-dose combination in chemically induced liver injury in rats. Rats were divided into 6 groups; Group 1, control, Group 2, injected with a single dose of a mixture of corn oil and carbon tetrachloride (CCl) to induce hepatic toxicity. Before CCl injection, Groups 3-6 were treated daily for 14 days with silymarin (SIL) (200 mg/kg), aescin (AES; 3. Read More

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http://dx.doi.org/10.1186/s13104-020-05094-2DOI Listing

Obstacles to intergenerational communication in caregivers' narratives regarding young people's sexual and reproductive health and lifestyle in rural South Africa.

BMC Public Health 2020 May 27;20(1):791. Epub 2020 May 27.

MRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Statistics from South Africa show the world's highest HIV prevalence with an estimated seven million people living with the virus. Several studies have pointed to communication about sexuality between parents/caregivers and children as a protective factor. However, communication between generations has been described as problematic, especially due to discomfort in discussing sexual matters. Read More

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http://dx.doi.org/10.1186/s12889-020-08780-9DOI Listing

An isolated vaginal metastasis from intestinal signet ring cell carcinoma: a case report and literature review.

BMC Cancer 2020 May 27;20(1):478. Epub 2020 May 27.

The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Background: Isolated vaginal metastases from intestinal signet ring cell carcinoma are extremely rare. There are no reported cases in the domestic or foreign literature. The characteristics of such cases of metastasis remain relatively unknown. Read More

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http://dx.doi.org/10.1186/s12885-020-06950-xDOI Listing

Evaluation of the morphometric covariation between palatal and craniofacial skeletal morphology in class III malocclusion growing subjects.

BMC Oral Health 2020 May 27;20(1):152. Epub 2020 May 27.

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

Background: To study the covariation between palatal and craniofacial skeletal morphology in Class III growing patients through geometric morphometric analysis (GMM).

Methods: In this retrospective study, 54 Class III subjects (24F,30M;7.6 ± 0. Read More

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http://dx.doi.org/10.1186/s12903-020-01140-4DOI Listing

Testing the efficacy of a minimal-guidance online self-help intervention for alcohol misuse in Estonia: study protocol of a randomized controlled trial.

BMC Public Health 2020 May 27;20(1):790. Epub 2020 May 27.

Estonian National Institute for Health Development, Tallinn, Estonia.

Background: Despite an initial steep decrease in alcohol misuse among Estonians through structural intervention means and the scaling up of alcohol counselling in the mid-2000's, most of the country's alcohol misuse indicators remain clearly higher than European averages. Consequently, an online self-help program was launched as part of an initial behavioral intervention initiative to foster progress in alcohol prevention on a population level.

Methods: A two-arm randomized controlled trial (RCT) has been designed to compare the efficacy of a culturally-adapted minimal-guidance online self-help program, the 8-week "Selge" online program against a control condition that consists of a self-administered test of alcohol use and advice regarding usual treatment in Estonia. Read More

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http://dx.doi.org/10.1186/s12889-020-08791-6DOI Listing

Discrimination between clinical significant and insignificant prostate cancer with apparent diffusion coefficient - a systematic review and meta analysis.

BMC Cancer 2020 May 27;20(1):482. Epub 2020 May 27.

Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.

Background: Prostate MRI has become a corner stone in diagnosis of prostate cancer (PC). Diffusion weighted imaging and the apparent diffusion coefficient (ADC) can be used to reflect tumor microstructure. The present analysis sought to compare ADC values of clinically insignificant with clinical significant PC based upon a large patient sample. Read More

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http://dx.doi.org/10.1186/s12885-020-06942-xDOI Listing

Cryptococcus meningitis mimicking cerebral septic emboli, a case report series demonstrating injection drug use as a risk factor for development of disseminated disease.

BMC Infect Dis 2020 May 27;20(1):381. Epub 2020 May 27.

Atrium Health Department of Medicine, Charlotte, NC, USA.

Background: Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if disseminated cryptococcal disease mimics cerebral septic emboli in injection drug use (IDU) leading to a search for endocarditis or other infectious sources. Though, IDU has been described as a potential risk for disseminated cryptococcal disease. Read More

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http://dx.doi.org/10.1186/s12879-020-05108-1DOI Listing

Frequency of anaplastic lymphoma kinase rearrangements in Moroccan patients with non small cell lung cancer: a multi-institutional national retrospective study.

BMC Cancer 2020 May 27;20(1):479. Epub 2020 May 27.

Research and investigation in medical oncology Moroccan group, Faculty of medicine and pharmacy, Mohammed V University, Impasse souissi, 10100, Rabat, Morocco.

Background: Anaplastic lymphoma kinase (ALK) rearrangement is a predictive factor of response to ALK inhibitors in non small cell lung cancer (NSCLC). The prevalence of ALK rearrangements is well known in Whites and Asians. However, data identifying the frequency of this rearrangement in Moroccan and North African population are lacking. Read More

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http://dx.doi.org/10.1186/s12885-020-06973-4DOI Listing

Development and validation of bile acid profile-based scoring system for identification of biliary atresia: a prospective study.

BMC Pediatr 2020 May 27;20(1):255. Epub 2020 May 27.

Department of Neonatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai, 200092, China.

Background: Early distinguishing biliary atresia from other causes of infantile cholestasis remains a major challenge. We aimed to develop and validate a scoring system based on bile acid for identification of biliary atresia.

Methods: In a prospective study, a total of 141 infants with cholestasis were enrolled in two sets (derivation cohort, n = 66; validation cohort, n = 75) from 2014 to 2018. Read More

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http://dx.doi.org/10.1186/s12887-020-02169-8DOI Listing

Geographic availability and accessibility of day care services for people with dementia in Ireland.

BMC Health Serv Res 2020 May 27;20(1):476. Epub 2020 May 27.

School of Business & Economics, National University of Ireland Galway, Galway, Ireland.

Background: Day care is an important service for many people with dementia and their carers. In Ireland, day care services for people with dementia are delivered by a mix of dementia-specific day care centres as well as generic day care centres that cater for people with dementia to various degrees. In this paper we examine the geographic distribution of day care services for people with dementia relative to potential need. Read More

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http://dx.doi.org/10.1186/s12913-020-05341-zDOI Listing

Intestinal parasitosis, anaemia and risk factors among pre-school children in Tigray region, northern Ethiopia.

BMC Infect Dis 2020 May 27;20(1):379. Epub 2020 May 27.

Department of Medical Microbiology, College of Health Sciences, Aksum University, Tigray, Ethiopia.

Background: Intestinal parasitic infections (IPIs) and anaemia are major health problems. This study assessed the prevalence of intestinal parasitic infections, anaemia and associated factors among pre-school children in rural areas of the Tigray region, northern Ethiopia.

Methods: A community based cross-sectional study was conducted among 610 pre-school children in rural communities of Northern Ethiopia from June 2017 to August 2017. Read More

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http://dx.doi.org/10.1186/s12879-020-05101-8DOI Listing

Association of genetic polymorphisms related to Johne's disease with estimated breeding values of Holstein sires for milk ELISA test scores.

BMC Vet Res 2020 May 27;16(1):165. Epub 2020 May 27.

Centre for Genetic Improvement of Livestock, Department of Animal Biosciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.

Background: Johne's disease (JD) is a chronic intestinal inflammatory disease caused by Mycobacterium avium subsp. paratuberculosis (MAP) infection in ruminants. Since there are currently no effective vaccine or treatment options available to control JD, genetic selection may be an alternative strategy to enhance JD resistance. Read More

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http://dx.doi.org/10.1186/s12917-020-02381-9DOI Listing

Identification of transcription factors MYC and C/EBPβ mediated regulatory networks in heart failure based on gene expression omnibus datasets.

BMC Cardiovasc Disord 2020 May 27;20(1):250. Epub 2020 May 27.

Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, FuZhou, 350001, FuJian, China.

Background: Heart failure is one of leading cause of death worldwide. However, the transcriptional profiling of heart failure is unclear. Moreover, the signaling pathways and transcription factors involving the heart failure development also are largely unknown. Read More

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http://dx.doi.org/10.1186/s12872-020-01527-9DOI Listing

A cost-of-illness analysis of β-Thalassaemia major in children in Sri Lanka - experience from a tertiary level teaching hospital.

BMC Pediatr 2020 May 27;20(1):257. Epub 2020 May 27.

Liverpool School of Tropical Medicine, Liverpool, UK.

Background: Sri Lanka has a high prevalence of β-thalassaemia major. Clinical management is complex and long-term and includes regular blood transfusion and iron chelation therapy. The economic burden of β-thalassaemia for the Sri Lankan healthcare system and households is currently unknown. Read More

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http://dx.doi.org/10.1186/s12887-020-02160-3DOI Listing

Protocol for the economic evaluation of the InTENSE program for rehabilitation of chronic upper limb spasticity.

BMC Health Serv Res 2020 May 27;20(1):478. Epub 2020 May 27.

Department of Neurosciences, Central Clinical School, Monash University, Melbourne, Australia.

Background: Assessment of the costs of care associated with chronic upper-limb spasticity following stroke in Australia and the potential benefits of adding intensive upper limb rehabilitation to botulinum toxin-A are key objectives of the InTENSE randomised controlled trial.

Methods: Recruitment for the trial has been completed. A total of 139 participants from 6 stroke units across 3 Australian states are participating in the trial. Read More

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http://dx.doi.org/10.1186/s12913-020-05333-zDOI Listing

Correction to: Effects of transversus abdominis plane block versus quadratus lumborum block on postoperative analgesia: a meta-analysis of randomized controlled trials.

BMC Anesthesiol 2020 May 27;20(1):128. Epub 2020 May 27.

Department of Anesthesiology, Sichuan Cancer Hospital & Institute, SichuanCancer Center, School of Medicine, University of Electronic Science andTechnology of China, No.55, Section 4, South Renmin Road, Chengdu, 610041, People's Republic of China.

An amendment to this paper has been published and can be accessed via the original article. Read More

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http://dx.doi.org/10.1186/s12871-020-01047-1DOI Listing

Prevalence and associated factors of scabies in Ethiopia: systematic review and Meta-analysis.

BMC Infect Dis 2020 May 27;20(1):380. Epub 2020 May 27.

Department of Epidemiology and Biostatistics, School of Public health, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high and continuous as neglected tropical disease of resource-poor settings, and particularly affects young age groups. Despite of these facts, studies conducted in Ethiopia regarding to the prevalence and associated factors for scabies infestation have been highly variable and didn't well compiled. Read More

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http://dx.doi.org/10.1186/s12879-020-05106-3DOI Listing

Community and health staff perceptions on non-communicable disease management in El Salvador's health system: a qualitative study.

BMC Health Serv Res 2020 May 27;20(1):474. Epub 2020 May 27.

Institute for Global Health and Development, Queen Margaret University, Edinburgh, UK.

Background: Non-communicable Diseases (NCDs) are the leading cause of global mortality and disability with a rising burden in low- and middle-income countries. Their multifactorial aetiology, and their requirement of long-term care, implies the need for comprehensive approaches. From 2009, the Ministry of Health (MoH) in El Salvador has developed a national public health system based on comprehensive primary health care. Read More

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http://dx.doi.org/10.1186/s12913-020-05249-8DOI Listing

Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs.

BMC Vet Res 2020 May 27;16(1):167. Epub 2020 May 27.

USDA, ARS, National Animal Disease Center, 1920 Dayton Ave, Ames, IA, 50010, USA.

Background: Glaesserella parasuis, the causative agent of Glӓsser's disease, is widespread in swine globally resulting in significant economic losses to the swine industry. Prevention of Glӓsser's disease in pigs has been plagued with an inability to design broadly protective vaccines, as many bacterin based platforms generate serovar or strain specific immunity. Subunit vaccines are of interest to provide protective immunity to multiple strains of G. Read More

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http://dx.doi.org/10.1186/s12917-020-02377-5DOI Listing

The effect of uric acid and urinary sodium excretion on prehypertension: a nationwide population-based study.

BMC Cardiovasc Disord 2020 May 27;20(1):251. Epub 2020 May 27.

Department of Internal Medicine, School of Medicine, Ewha Womans University, 1071, Anyangcheon-ro, Yangcheon-gu, Seoul, 158-710, Korea.

Background: This study examined the effect of serum uric acid (SUA) level and urinary sodium excretion on blood pressure as well as their combined effect on prehypertension in a Korean population.

Method: Data from the 7th Korea National Health and Nutrition Examination Survey for adults (≥ 19 years of age) were used. The participants were classified into two groups, normotension and prehypertension, according to the JNC-7 definition. Read More

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http://dx.doi.org/10.1186/s12872-020-01535-9DOI Listing

Molecular detection of porcine reproductive and respiratory syndrome virus, porcine circovirus 2 and hepatitis E virus in oral fluid compared to their detection in faeces and serum.

BMC Vet Res 2020 May 27;16(1):164. Epub 2020 May 27.

Clinic for Ruminants and Pigs, Clinic for Reproduction and Farm Animals, Veterinary Faculty University of Ljubljana, Ljubljana, Slovenia.

Background: Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Porcine Circovirus Type 2 (PCV2) and Hepatitis E virus (HEV) are common and economically important viral disease causative agents detected in pig oral fluid (OF), faeces and serum at some infection stages. The purpose of this study was to detect PRRSV, PCV2 and HEV on six pig farms to determine which of the three sample types, OF, faeces or serum is appropriate for the diagnosis of these viruses in different pig categories. The following pig categories were included: 5 weeks-old (w/o), 7 w/o, 9 w/o, 11 w/o weaners, fatteners and breeding sows. Read More

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http://dx.doi.org/10.1186/s12917-020-02378-4DOI Listing

A case report of iatrogenic gas gangrene post colonoscopy successfully treated with conservative management- is surgery always necessary?

BMC Gastroenterol 2020 May 27;20(1):163. Epub 2020 May 27.

The Mater Hospital, Townsville, Australia.

Background: Colonoscopy is a routine procedure in diagnosis and treatment of colonic disease. While generally regarded as a safe procedure, potentially fatal complications can occur. Gas gangrene is one such complication, with very high mortality. Read More

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http://dx.doi.org/10.1186/s12876-020-01314-yDOI Listing

Lagovirus europeus GI.2 (rabbit hemorrhagic disease virus 2) infection in captive mountain hares (Lepus timidus) in Germany.

BMC Vet Res 2020 May 27;16(1):166. Epub 2020 May 27.

Institute of Pathology, University of Veterinary Medicine Hanover, Foundation, Buenteweg, 17 30559, Hannover, Germany.

Background: Rabbit hemorrhagic disease virus (RHDV, Lagovirus europeus GI.1) induces a contagious and highly lethal hemorrhagic disease in rabbits. In 2010 a new genotype of lagovirus (GI. Read More

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http://dx.doi.org/10.1186/s12917-020-02386-4DOI Listing

Report: central diabetes insipidus and schwannoma in a male with X-linked congenital adrenal hypoplasia.

BMC Endocr Disord 2020 May 27;20(1):73. Epub 2020 May 27.

Department of Pediatrics, Gyeongsang National University School of Medicine, 92 Chilam-dong, Jinju, Gyeongnam, 660-751, South Korea.

Background: DAX1 mutations are related to the X-linked form of adrenal hypoplasia congenita (AHC) in infancy and to hypogonadotropic hypogonadism (HH) in puberty. We report a male patient affected by X-linked AHC who presented with central diabetes insipidus and schwannoma in adulthood, which has not been described in association with AHC.

Case Presentation: A 36-day-old male infant who presented with severe dehydration was admitted to the intensive care unit. Read More

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http://dx.doi.org/10.1186/s12902-020-00553-0DOI Listing

Can cluster analyses of linked healthcare data identify unique population segments in a general practice-registered population?

BMC Public Health 2020 May 27;20(1):798. Epub 2020 May 27.

Cwm Taf Morgannwg University Health Board, Ynysmeurig House, Navigation Park, Abercynon, Mountain Ash, CF45 4SN, UK.

Background: Population segmentation is useful for understanding the health needs of populations. Expert-driven segmentation is a traditional approach which involves subjective decisions on how to segment data, with no agreed best practice. The limitations of this approach are theoretically overcome by more data-driven approaches such as utilisation-based cluster analysis. Read More

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http://dx.doi.org/10.1186/s12889-020-08930-zDOI Listing

The efficacy of a mobile phone application to improve adherence to treatment and self-management in people with chronic respiratory disease in Romanian population - a pilot study.

BMC Health Serv Res 2020 May 27;20(1):475. Epub 2020 May 27.

Internal Medicine Discipline, Medical Clinical Disciplines I, "Ovidius" University of Constanta, Faculty of Medicine, Constanta, Romania.

Background: Many studies assessed the effect of mobile phone applications on self-management outcomes in patients with asthma, but all of them presented variable results. In this paper. we examined the effect of a mobile phone application on self-management and disease control in Romanian population. Read More

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http://dx.doi.org/10.1186/s12913-020-05340-0DOI Listing

Elevated hemoglobin A1c is associated with the presence of pancreatic cysts in a high-risk pancreatic surveillance program.

BMC Gastroenterol 2020 May 27;20(1):161. Epub 2020 May 27.

Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA.

Background: Emerging evidence demonstrates that surveillance of individuals at high-risk (HRIs) of developing pancreatic adenocarcinoma allows for identification and treatment of resectable tumors with improved survival. Population-based data suggest that hyperglycemia may be present up to three years before the development of pancreatic cancer. We investigated whether elevated hemoglobin A1c (HbA1c) is associated with the development of pancreatic cysts in a pancreatic surveillance program. Read More

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http://dx.doi.org/10.1186/s12876-020-01308-wDOI Listing