7,723 results match your criteria BMC research notes[Journal]


Prevalence of hepatitis C in the adult population of Bulgaria: a pilot study.

BMC Res Notes 2020 Jul 7;13(1):326. Epub 2020 Jul 7.

Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.

Objective: This study piloted a European technical protocol for conducting chronic hepatitis C prevalence surveys in the general population. The pilot study took place in the Bulgarian city of Stara Zagora in 2018, and results of setting up, conducting and evaluating the survey are presented.

Results: A probability-based sample of the general adult population was drawn from the local population registry, stratified by age and sex. Read More

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http://dx.doi.org/10.1186/s13104-020-05158-3DOI Listing

Inter-agency collaboration factors affecting multidisciplinary workers' ability to identify child maltreatment.

BMC Res Notes 2020 Jul 6;13(1):323. Epub 2020 Jul 6.

Department of Psychiatry, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba, Chiba, 260-8670, Japan.

Objectives: This study aimed to clarify the factors of successful inter-agency collaboration that affect multidisciplinary workers' abilities to identify child maltreatment. A questionnaire-based survey was conducted; the contents of the questionnaire included the Collaboration Evaluation Scale we developed and the workers' abilities to identify child maltreatment. In total, 277 individuals from various agencies in Japan participated in this study. Read More

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http://dx.doi.org/10.1186/s13104-020-05162-7DOI Listing

Prevalence of Helicobacter pylori among Sudanese patients diagnosed with colon polyps and colon cancer using immunohistochemistry technique.

BMC Res Notes 2020 Jul 6;13(1):322. Epub 2020 Jul 6.

Department of Histopathology and Cytology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.

Objectives: Infection with the bacteria Helicobacter pylori has been classified as class one carcinogen associated with increasing susceptibility of gastritis and gastric carcinoma. This study is aiming at investigating the prevalence of H. pylori among colon polyps and colon cancer patients. Read More

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http://dx.doi.org/10.1186/s13104-020-05159-2DOI Listing

Enzymatic activity and brine shrimp lethality of venom from the large brown spitting cobra (Naja ashei) and its neutralization by antivenom.

BMC Res Notes 2020 Jul 6;13(1):325. Epub 2020 Jul 6.

Department of Pharmacology and Toxicology, Moi University, Eldoret, Kenya.

Objective: Naja ashei is a snake of medical importance in Kenya, Ethiopia, Somalia, Uganda, and Tanzania. Little is known about the enzymatic (snake venom phospholipases A; svPLA's) and toxic (lethal) activities of N. ashei venom and crucially, the safety and capacity of available antivenom to neutralize these effects. Read More

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http://dx.doi.org/10.1186/s13104-020-05167-2DOI Listing

Scintigraphy evaluation of hyperthyroidism and its correlation with clinical and biochemical profiles.

BMC Res Notes 2020 Jul 6;13(1):324. Epub 2020 Jul 6.

Taif University School of Medicine, Taif, Saudi Arabia.

Objective: Hyperthyroidism is the excessive synthesis of thyroid hormones. Thyroid uptake scans and ultrasonography provide an accurate diagnosis of hyperthyroidism, especially when thyroid receptor antibody (TRAb) measurement is not readily available. This study explored the prevalence of various hyperthyroidism causes using retrospective scintigraphy results and evaluated their relationship with clinical, biochemical, and sonographic imaging parameters from patients who underwent Tc-pertechnetate thyroid scans between 2016 and 2019 in Taif, Saudi Arabia, where literature is insufficient. Read More

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http://dx.doi.org/10.1186/s13104-020-05164-5DOI Listing

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation.

BMC Res Notes 2020 Jul 3;13(1):321. Epub 2020 Jul 3.

Department of Life Sciences, College of Biosciences and Biotechnology, National Cheng Kung University, No. 1 University Road, East Dist.,, Tainan City, 701, Taiwan (R.O.C.).

Objective: Palladin is a ubiquitous phosphoprotein expressed in vertebrate cells that works as a scaffolding protein. Several isoforms deriving from alternative splicing are originated from the palladin gene and involved in mesenchymal and muscle cells formation, maturation, migration, and contraction. Recent studies have linked palladin to the invasive spread of cancer and myogenesis. Read More

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http://dx.doi.org/10.1186/s13104-020-05152-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333403PMC

Whole genome sequence of five strains of Spiroplasma citri isolated from different host plants and its leafhopper vector.

BMC Res Notes 2020 Jul 3;13(1):320. Epub 2020 Jul 3.

Department of Microbiology and Plant Pathology, University of California, Riverside, CA, 92521, USA.

Objectives: Spiroplasma citri is a bacterium with a wide host range and is the causal agent of citrus stubborn and brittle root diseases of citrus and horseradish, respectively. S. citri is transmitted in a circulative, persistent manner by the beet leafhopper, Neoaliturus (Circulifer) tenellus (Baker), in North America. Read More

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http://dx.doi.org/10.1186/s13104-020-05160-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333264PMC

Analysis of medico-social factors for return to work among patients presenting with haematological malignancy (adamantine): results of a 'pilot study'.

BMC Res Notes 2020 Jul 2;13(1):313. Epub 2020 Jul 2.

INSERM U1086 « ANTICIPE », 14033, Caen Cedex, France.

Objective: The aim of this study was to describe return to work determinants in patients with haematological malignancy.

Results: This medico-social pilot study included patients with haematological malignancy in the département of Calvados, aged 18 to 55 years, diagnosed between 1st January and 31st December 2010 and alive at 1st January 2015. Patients were identified via consultation of the Lower Normandy haematological malignancy Registry. Read More

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http://dx.doi.org/10.1186/s13104-020-05149-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331231PMC

Emergence of multidrug-resistant non-fermentative gram negative bacterial infection in hospitalized patients in a tertiary care center of Nepal.

BMC Res Notes 2020 Jul 2;13(1):319. Epub 2020 Jul 2.

Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Objective: This study was designed for the characterization and establishment of antibiotic susceptibility profiles of non-fermentative gram negative bacteria isolated from hospitalized patients in a tertiary care hospital of Nepal.

Results: A total of 402 non-fermentative gram negative bacteria was isolated in 1486 culture-positive cases from 6216 different clinical samples obtained from hospitalized patients. Among total non-fermentative gram negative bacterial isolates, the highest number was recovered from specimens collected from lower respiratory tract infections (n = 173, 43. Read More

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http://dx.doi.org/10.1186/s13104-020-05163-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330544PMC

Moderate rate of transmitted resistance mutations to antiretrovirals and genetic diversity in newly HIV-1 patients diagnosed in Benin.

BMC Res Notes 2020 Jul 2;13(1):314. Epub 2020 Jul 2.

Institute for Health Research, Epidemiological Surveillance and Training of Senegal, Dakar, Senegal.

Objective: Seventeen years after the start of the IBAARV (Beninese initiative for access to antiretrovirals), transmitted drug resistance mutations in ARV-naïve patients and HIV-1 genetic diversity were investigated in Benin.

Results: Drug resistance mutations were detected in (27/248; 10.9%) according to the WHO SDRM 2009 list, with a predominance of mutations directed against NNRTIs drugs (24/248; 10%). Read More

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http://dx.doi.org/10.1186/s13104-020-05151-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330984PMC

Changes in relative histone abundance and heterochromatin in αA-crystallin and αB-crystallin knock-in mutant mouse lenses.

BMC Res Notes 2020 Jul 2;13(1):315. Epub 2020 Jul 2.

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8096, St. Louis, MO, 63110, USA.

Objective: Understanding the mechanisms of cataract formation is important for age-related and hereditary cataracts caused by mutations in lens protein genes. Lens proteins of the crystallin gene families α-, β-, and γ-crystallin are the most abundant proteins in the lens. Single point mutations in crystallin genes cause autosomal dominant cataracts in multigenerational families. Read More

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http://dx.doi.org/10.1186/s13104-020-05154-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331185PMC

Frequency distribution of IL-17A G197A (rs2275913) and IL-17F A7488G (rs763780) polymorphisms among healthy Sudanese population.

BMC Res Notes 2020 Jul 2;13(1):317. Epub 2020 Jul 2.

Department of Molecular Biology, Institute of Parasitology, University of Leipzig, Leipzig, Germany.

Objectives: IL-17A G197A and IL-17F A7488G polymorphisms has been identified to be associated with the susceptibility to many diseases. This study aimed to investigate the frequency distribution of IL-17A G197A and IL-17F A7488G polymorphisms among healthy Sudanese population. A descriptive cross-sectional hospital-based molecular study conducted in different sites throughout Sudan. Read More

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http://dx.doi.org/10.1186/s13104-020-05165-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330939PMC

Establishment of reference range of CD4 T-lymphocyte in healthy Nepalese adults.

BMC Res Notes 2020 Jul 2;13(1):316. Epub 2020 Jul 2.

Central Department of Biotechnology, Institute of Science and Technology, Tribhuvan University, Kathmandu, Nepal.

Objective: CD4 T lymphocytes are the most widely used cellular markers to assess the course of HIV infection, clinical staging and, monitoring the effect of antiretroviral therapy. The regional reference range for Eastern, Central and Western development region of Nepal had already been established whereas the same was still lacking in Mid-western and Far-western development region. The objective of this study was to establish reference range of CD4 T lymphocyte in the remaining two development regions and finally the national reference range using data from previous study. Read More

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http://dx.doi.org/10.1186/s13104-020-05156-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330941PMC

Detecting bracoviral orthologs distribution in five tsetse fly species and the housefly genomes.

BMC Res Notes 2020 Jul 2;13(1):318. Epub 2020 Jul 2.

Centre for Biotechnology and Bioinformatics, University of Nairobi, P.O. Box 30197, Nairobi, 00100, Kenya.

Objective: Mutualism between endogenous viruses and eukaryotes is still poorly understood. Several endogenous double-stranded polydnaviruses, bracoviruses, homologous to those present in parasitic braconid wasp genomes were detected in the tsetse fly (Glossina morsitans morsitans). This is peculiar since tsetse flies do not share a reproductive lifestyle similar to wasps, but deliver fully developed larvae that pupate within minutes of exiting their mothers. Read More

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http://dx.doi.org/10.1186/s13104-020-05161-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331153PMC

Wound healing potential: evaluation of molecular profiling and amplification of Lucilia sericata angiopoietin-1 mRNA mid-part.

BMC Res Notes 2020 Jul 1;13(1):308. Epub 2020 Jul 1.

Department of Medical Entomology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: High prevalence of chronic ulcers and the burden of disease necessitate the increasingly significant production of new recombinant proteins in the world. The angiopoietin-1 enzyme is a part of the growth factors group which is secreted by Lucilia sericata (Diptera: Calliphoridae) larvae when they meet lesions to ensure maggot therapy. It is one of the most potent proteins in wound healing. Read More

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http://dx.doi.org/10.1186/s13104-020-05141-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329540PMC

Descriptive epidemiology of objectively-measured, free-living sleep parameters in a rural African setting.

BMC Res Notes 2020 Jul 1;13(1):310. Epub 2020 Jul 1.

Department of Pathology and Medical Sciences, University of Limpopo (Turfloop Campus), Sovenga, Limpopo, South Africa.

Objectives: To investigate the descriptive nature of objectively-measured, free-living sleep quantity and quality, and the relationship to adiposity, in a rural African setting in 145 adults (≥ 40 years, female: n = 104, male: n = 41). Wrist-mounted, triaxial accelerometry data was collected over 9 days. Measures of sleep quantity and quality, and physical activity were extracted from valid minute-by-minute data. Read More

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http://dx.doi.org/10.1186/s13104-020-05153-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329391PMC

Lessons learned through piloting a community-based SMS referral system for common mental health disorders used by female community health volunteers in rural Nepal.

BMC Res Notes 2020 Jul 1;13(1):309. Epub 2020 Jul 1.

Duke Global Health Institute, Duke University, Durham, NC, USA.

Objective: The Community Informant Detection Tool (CIDT) is a paper-based proactive case detection strategy with evidence for improving help-seeking behavior for mental healthcare. Key implementation barriers for the paper-based CIDT include delayed reporting of cases and lack of active follow up. We used mobile phones and structured text messages to improve timeliness of case reporting, encouraging follow up, and case record keeping. Read More

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http://dx.doi.org/10.1186/s13104-020-05148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328268PMC

Expression of the miR-200 family in tumor tissue, plasma and urine of epithelial ovarian cancer patients in comparison to benign counterparts.

BMC Res Notes 2020 Jul 1;13(1):311. Epub 2020 Jul 1.

Department of Obstetrics and Gynecology, Tampere University Hospital, P.O.box 2000, 33521, Tampere, Finland.

Objective: Plasma, but also urine sample could represent a simple liquid biopsy for ovarian cancer biomarker detection. The miRNA-200 family has been shown to be dysregulated in ovarian cancer. The aim of this study was to isolate three members of miR-200 family from tumor tissue, plasma and urine of high-grade serous ovarian cancer patients in comparison with samples from patients with benign ovarian tumors. Read More

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http://dx.doi.org/10.1186/s13104-020-05155-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329467PMC

Detection of several carbapenems resistant and virulence genes in classical and hyper-virulent strains of Klebsiella pneumoniae isolated from hospitalized neonates and adults in Khartoum.

BMC Res Notes 2020 Jul 1;13(1):312. Epub 2020 Jul 1.

Biochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, 21452, Saudi Arabia.

Objective: Klebsiella pneumoniae (K. pneumoniae) involves both community-acquired and nosocomial infections. It is responsible for a wide variety of infections, including infections of the urinary tract, pneumonia, bacteremia, meningitis, wound infection and purulent abscesses. Read More

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http://dx.doi.org/10.1186/s13104-020-05157-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328261PMC

Trends in measures of handgrip strength from 2014 to 2017 among Korean adolescents using the Korean National Health and Nutrition Examination Survey Data.

BMC Res Notes 2020 Jun 30;13(1):307. Epub 2020 Jun 30.

Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Object: Measuring handgrip strength is a useful method to evaluate sarcopenia. No study has shown the trends of handgrip strength to weight ratio among Korean adolescents by year. This study aimed to determine the trends of handgrip strength among Korean adolescents using data from the Korea National Health and Nutrition Examination Survey (KNHANES). Read More

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http://dx.doi.org/10.1186/s13104-020-05112-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329499PMC

Associations of perceived neighborhood environment and physical activity with metabolic syndrome among Mexican-Americans adults: a cross sectional examination.

BMC Res Notes 2020 Jun 26;13(1):306. Epub 2020 Jun 26.

College of Health Solutions and Southwest Interdisciplinary Research Center, Arizona State University, 500 N 3rd Street, Phoenix, AZ, 85004, USA.

Objective: This secondary data analysis examined associations among perceived neighborhood environmental factors, physical activity (PA), and the presence of metabolic syndrome (MS) in Mexican-American (MA) adults. Seventy-five MA adults (mean age of 37.9 ± 9. Read More

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http://dx.doi.org/10.1186/s13104-020-05143-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320589PMC

Prevalence and susceptibility to antibiotics from Campylobacter jejuni and Campylobacter coli isolated from chicken meat in southern Benin, West Africa.

BMC Res Notes 2020 Jun 26;13(1):305. Epub 2020 Jun 26.

Laboratory of Food Microbiology, Ministry of Health, 01, P.O. Box 418, Cotonou, Benin.

Objective: Poultry is commonly considered to be the primary vehicle for Campylobacter infection in humans. The aim of this study is to assess the risk of Campylobacteriosis in chicken meat consumers in southern Benin by assessing the prevalence and resistance profile of Campylobacter coli and Campylobacter jejuni isolated from chicken thigh in Southern Benin.

Results: The contamination rate of Campylobacter in the samples was 32. Read More

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http://dx.doi.org/10.1186/s13104-020-05150-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318530PMC

Early exposure to environment sounds and the development of cortical auditory evoked potentials of preterm infants during the first 3 months of life.

BMC Res Notes 2020 Jun 26;13(1):303. Epub 2020 Jun 26.

Department of Electrical and Biomedical Engineering, Institute of Technology, Federal University of Pará, Rua Augusto Correa, S/N, Belém, PA, 66075-110, Brazil.

Objective: Preterm infants are exposed earlier than their term counterparts to unattenuated sounds from the external environment during the sensitive period of the organization of the auditory cortical circuitry. In the current study, we investigate the effect of preterm birth on the course of development of auditory cortical areas by evaluating how gestational age (GA) correlates with the latency of the P1 component of the cortical auditory evoked potential (CAEP) of two experimental groups measured at 1 or 3 months of age.

Results: Our sample consisted of 23 infants delivered at GA ranging from 31. Read More

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http://dx.doi.org/10.1186/s13104-020-05129-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318486PMC

Repeated assessment of work-related exhaustion: the temporal stability of ratings in the Lund University Checklist for Incipient Exhaustion.

BMC Res Notes 2020 Jun 26;13(1):304. Epub 2020 Jun 26.

Department of Psychology, Lund University, Lund, 22100, Sweden.

Objective: Screening inventories are important tools in clinical settings and research but may be sensitive to temporary fluctuations. Therefore, we revisited data from a longitudinal study with the Lund University Checklist for Incipient Exhaustion (LUCIE) that comprised occupationally active individuals (n = 1355; 27-52 years; 57% women) and one initial paper and pencil survey and 10 subsequent equally spaced online surveys. In the present study we examine to what extent the LUCIE scores changed across 3 years (11 assessments) and whether episodes of temporary elevated LUCIE scores (LTE) coincided with reports of negative or positive changes at work or in private life. Read More

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http://dx.doi.org/10.1186/s13104-020-05142-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318754PMC

Post-developmental extracellular proteoglycan maintenance in attractin-deficient mice.

BMC Res Notes 2020 Jun 24;13(1):301. Epub 2020 Jun 24.

Department of Medical Oncology, Dana-Farber Cancer Institute, JF517, 450 Brookline Avenue, Boston, MA, 02215, USA.

Objective: Neurodegeneration and hair pigmentation alterations in mice occur consequent to aberrations at the Atrn locus coding for the transmembrane form of attractin. Earlier results pointed to a possible involvement in intracellular trafficking/export of secretory vesicles containing proteoglycan. Here we examined kidney and liver, both heavily dependent upon proteoglycan, of attractin-deficient mice to determine whether abnormalities were observed in these tissues. Read More

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http://dx.doi.org/10.1186/s13104-020-05130-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313179PMC

A video protocol for rapid dissection of mouse dorsal root ganglia from defined spinal levels.

BMC Res Notes 2020 Jun 24;13(1):302. Epub 2020 Jun 24.

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.

Objective: Dorsal root ganglia (DRG) are heterogeneous assemblies of assorted sensory neuron cell bodies found in bilateral pairs at every level of the spinal column. Pseudounipolar afferent neurons convert external stimuli from the environment into electrical signals that are retrogradely transmitted to the spinal cord dorsal horn. To do this, they extend single axons from their DRG-resident somas that then bifurcate and project both centrally and distally. Read More

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http://dx.doi.org/10.1186/s13104-020-05147-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313212PMC

Immunohistochemical expression of interleukin-17 and hormonal receptors in benign and malignant breast lesions.

BMC Res Notes 2020 Jun 23;13(1):300. Epub 2020 Jun 23.

Department of Histopathology and Cytology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.

Objectives: IL17 is a critical pro-inflammatory cytokine that is involved in inflammation, multidrug resistance and growth persistence pathways in cancer. This study is aiming at studying the expression of IL17 and hormonal receptors expression in benign and malignant breast lesions using immunohistochemical staining methods.

Results: A total of 137 cases of breast lesions were studied, 97 (70. Read More

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http://dx.doi.org/10.1186/s13104-020-05146-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310502PMC

Plant and mouse EB1 proteins have opposite intrinsic properties on the dynamic instability of microtubules.

BMC Res Notes 2020 Jun 22;13(1):296. Epub 2020 Jun 22.

Department of Cell Biology, Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198, Gif-Sur-Yvette Cedex, France.

Objective: Most eukaryotic cells contain microtubule filaments, which play central roles in intra-cellular organization. However, microtubule networks have a wide variety of architectures from one cell type and organism to another. Nonetheless, the sequences of tubulins, of Microtubule Associated proteins (MAPs) and the structure of microtubules are usually well conserved throughout the evolution. Read More

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http://dx.doi.org/10.1186/s13104-020-05139-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310003PMC

Qualitative and quantitative assay of glucose 6 phosphate dehydrogenase in patients attending tertiary care center.

BMC Res Notes 2020 Jun 22;13(1):298. Epub 2020 Jun 22.

Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa, Nepal.

Objectives: The study was carried out with the aim to find out the frequency of Glucose 6 phosphate dehydrogenase (G6PD) deficiency among the patients attending the hospital and to rationalize the qualitative methemoglobin reduction test in reference to the quantitative spectrophotometric assay. Timely screening of the patients for G6PD with appropriate screening method can play an important role in preventing hemolytic crisis that arises from therapeutic use of oxidative drugs like primaquine.

Result: The frequency of G6PD deficient cases was 3% by both of the employed tests. Read More

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http://dx.doi.org/10.1186/s13104-020-05145-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310380PMC

A pilot study on a potential relationship between leg bone length and sprint performance in sprinters; are there any event-related differences in 100-m and 400-m sprints?

BMC Res Notes 2020 Jun 22;13(1):297. Epub 2020 Jun 22.

Faculty of Sport and Health Science, Ritsumeikan University, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.

Objective: This study examined the relationship between leg bone length and sprint performance in sprinters. The leg bone lengths in 28 100-m specialized sprinters and 28 400-m specialized sprinters were measured using magnetic resonance imaging. The lengths of the upper and lower leg bones were assessed by calculating the lengths of the femur and tibia, respectively. Read More

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http://dx.doi.org/10.1186/s13104-020-05140-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309971PMC

Electro-oculography in bilateral optic neuropathy.

BMC Res Notes 2020 Jun 12;13(1):287. Epub 2020 Jun 12.

Department of Physiology, Faculty of Medicine, University of Peradeniya, Peradeniya, 20400, Sri Lanka.

Objective: Effect of bilateral, optic neuropathy on the function of retinal pigment epithelium has not been investigated extensively to date. This study aimed to determine the effect of bilateral, optic neuropathy on light peak:dark trough ratio, light peak and dark trough values of electro-oculography. Thirty-seven patients with a clinical diagnosis of bilateral optic neuropathy and 40 control subjects were recruited in this observational, cross-sectional study, carried out at the Neurophysiology unit, Teaching Hospital, Peradeniya, Sri Lanka. Read More

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http://dx.doi.org/10.1186/s13104-020-05131-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310542PMC

Neuromuscular activation pattern of lower extremity muscles during pedaling in cyclists with single amputation of leg and with two legs: a case study.

BMC Res Notes 2020 Jun 22;13(1):299. Epub 2020 Jun 22.

Nippon Sport Science University, Tokyo, Japan.

Objective: In Para-cycling competitions, cyclists with amputation of one-leg and no prosthesis, i.e., Division Cycle, Sport Class C2, perform pedaling movement on bicycle by unilateral leg. Read More

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http://dx.doi.org/10.1186/s13104-020-05144-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310265PMC

Immunohistochemical expression of Cyclin D1 among Sudanese patients diagnosed with benign and malignant prostatic lesions.

BMC Res Notes 2020 Jun 17;13(1):295. Epub 2020 Jun 17.

Department of Cytology and Histopathology, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.

Objectives: Prostate cancer (PC) is common cancer worldwide. Several markers have been developed to differentiate between benign prostatic hyperplasia (BPH) from PC. A descriptive retrospective hospital-based study aimed at determining the expression of Cyclin D1 in BPH and PC. Read More

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http://dx.doi.org/10.1186/s13104-020-05138-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302005PMC

Salivary β2-microglobulin levels in patients with erosive oral lichen planus and squamous cell carcinoma.

BMC Res Notes 2020 Jun 17;13(1):294. Epub 2020 Jun 17.

Dental Research Center and Department of Oral Medicine, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.

Objectives: β2 microglobulin, as a biomarker, is used for the diagnosis of oral malignant and pre-malignant lesions. The components of the microglobulin system can directly or indirectly help grow and develop tumors. The present study aims to compare beta-2 microglobulin levels in patients with lichen planus of the esophagus, oral squamous cell carcinoma, and healthy individuals. Read More

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http://dx.doi.org/10.1186/s13104-020-05135-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301459PMC

Comparative therapeutic index, lethal time and safety margin of various toxicants and snake antivenoms using newly derived and old formulas.

BMC Res Notes 2020 Jun 16;13(1):292. Epub 2020 Jun 16.

Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Federal University of Agriculture, P.M.B. 2373, Makurdi, Benue, Nigeria.

Objective: The assessment of clinical efficacy and toxicity is very important in pharmacology and toxicology. The effects of psychostimulants (e.g. Read More

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http://dx.doi.org/10.1186/s13104-020-05134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296648PMC

SOCRATES: an online tool leveraging a social contact data sharing initiative to assess mitigation strategies for COVID-19.

BMC Res Notes 2020 Jun 16;13(1):293. Epub 2020 Jun 16.

Centre for Health Economic Research and Modelling Infectious Diseases, University of Antwerp, Antwerp, Belgium.

Objective: Establishing a social contact data sharing initiative and an interactive tool to assess mitigation strategies for COVID-19.

Results: We organized data sharing of published social contact surveys via online repositories and formatting guidelines. We analyzed this social contact data in terms of weighted social contact matrices, next generation matrices, relative incidence and R[Formula: see text]. Read More

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http://dx.doi.org/10.1186/s13104-020-05136-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296890PMC

Ultrastructural alterations in Plasmodium falciparum induced by chalcone derivatives.

BMC Res Notes 2020 Jun 15;13(1):290. Epub 2020 Jun 15.

Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Objective: Chalcones (1, 3-diaryl-2-propen-1-ones) and their derivatives are widely explored from the past decade for its antimalarial activity. To elucidate their mechanism of action on the malaria parasite, the ultrastructural changes with the action of these derivatives in different organelles of the parasite were studied in vitro. Infected RBCs [CQ sensitive (MRC-2) and CQ resistant (RKL-9) Plasmodium strain] were treated with three chalcone derivatives 1, 2 and 3 and standard drugs, i. Read More

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http://dx.doi.org/10.1186/s13104-020-05132-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296763PMC

Application of median lethal concentration (LC) of pathogenic microorganisms and their antigens in vaccine development.

BMC Res Notes 2020 Jun 15;13(1):289. Epub 2020 Jun 15.

Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Federal University of Agriculture, P.M.B. 2373, Makurdi, Benue, Nigeria.

Objective: Lack of ideal mathematical models to qualify and quantify both pathogenicity, and virulence is a dreadful setback in development of new antimicrobials and vaccines against resistance pathogenic microorganisms. Hence, the modified arithmetical formula of Reed and Muench has been integrated with other formulas and used to determine bacterial colony forming unit/viral concentration, virulence and immunogenicity.

Results: Microorganisms' antigens tested are Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa in mice and rat, Edwardsiella ictaluri, Aeromonas hydrophila, Aeromonas veronii in fish, New Castle Disease virus in chicken, Sheep Pox virus, Foot-and-Mouth Disease virus and Hepatitis A virus in vitro, respectively. Read More

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http://dx.doi.org/10.1186/s13104-020-05126-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294769PMC

The predictive value of red cell distribution width for stroke severity and outcome.

BMC Res Notes 2020 Jun 15;13(1):288. Epub 2020 Jun 15.

Neuroscience Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Objectives: In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA).

Results: In this prospective study, 282 stroke patients who underwent tPA injection were included. The categorization of RDW to < 12. Read More

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http://dx.doi.org/10.1186/s13104-020-05125-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294627PMC

Kyasanur Forest disease virus non-mouse animal models: a pilot study.

BMC Res Notes 2020 Jun 15;13(1):291. Epub 2020 Jun 15.

Applied Biosafety Research Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada.

Objectives: Mouse models have delivered variable recapitulation of Kyasanur Forest disease (KFD) pathology and consistently demonstrated neurological involvement which may be a limited feature of human disease. With the purpose of more accurately modelling human disease progression we infected several small-mammalian models: guinea pigs, hamsters and ferrets with a titered infectious dose of Kyasanur Forest disease virus (KFDV). Clinical indicators of disease severity were observed for seventeen days, on day eighteen a visual post-mortem analysis of visceral organs was conducted. Read More

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http://dx.doi.org/10.1186/s13104-020-05137-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296627PMC

Pilot prospective open-label one-arm trial investigating intrathecal Adenosine in neuropathic pain after lumbar discectomy.

BMC Res Notes 2020 Jun 12;13(1):284. Epub 2020 Jun 12.

Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Science, Tabriz, Iran.

Objectives: Adenosine has an analgesic and anti-inflammatory role and its injections are used for perioperative pain management. We aimed to study efficacy of intrathecal injection of adenosine for post-operative radicular pain after lumbar discectomy. Forty patients with unilevel lumbar discectomy who had radicular lower limb pain were treated by 1000 micrograms of intrathecal injection of adenosine in this single-arm prospective open-label trial between November 2015 to October 2016. Read More

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http://dx.doi.org/10.1186/s13104-020-05133-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291557PMC

Low food and nutrition literacy (FNLIT): a barrier to dietary diversity and nutrient adequacy in school age children.

BMC Res Notes 2020 Jun 12;13(1):286. Epub 2020 Jun 12.

Department of Nutrition Research, National Nutrition and Food Technology Research Institute (WHO Collaborating Center) and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objective: This study aims to assess the relationship between Food and Nutrition Literacy (FNLIT) and dietary diversity score (DDS); FNLIT and nutrient adequacy (NAR%, MAR%) in school-age children in Iran.

Results: This cross-sectional study was undertaken on 803 primary school students in Tehran, Iran. Socio-economic, as well as three 24-h dietary recalls were collected through interviewing students and their mothers/caregivers. Read More

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http://dx.doi.org/10.1186/s13104-020-05123-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291429PMC

Determination of efficacy and toxicity of diclofenac microemulsion formulation for musculoskeletal pain: an observational study.

BMC Res Notes 2020 Jun 12;13(1):285. Epub 2020 Jun 12.

Department of Family Medicine/Faculty of Medicine and Dentistry, University of Alberta, 6-10 University Terrace, Edmonton, AB, T6G 2T4, Canada.

Objective: Musculoskeletal pain is often caused by injury to the bones, muscles, tendons, ligaments or nerves. Symptoms can be localized or generalized. Mild-moderate symptoms are treated with topical/oral over the counter drugs. Read More

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http://dx.doi.org/10.1186/s13104-020-05120-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291466PMC

Physical activity and blood gene expression profiles: the Norwegian Women and Cancer (NOWAC) Post-genome cohort.

BMC Res Notes 2020 Jun 11;13(1):283. Epub 2020 Jun 11.

Department of Community Medicine, UiT The Arctic University of Norway, Tromsö, Norway.

Objectives: The influence of physical activity (PA) on the immune system has emerged as a new field of research. Regular PA may promote an anti-inflammatory state in the body, thus contributing to the down-regulation of pro-inflammatory processes related to the onset and progression of multiple diseases. We aimed to assess whether overall PA levels were associated with differences in blood gene expression profiles, in a cohort of middle-aged Norwegian women. Read More

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http://dx.doi.org/10.1186/s13104-020-05121-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291748PMC

Subcellular localization of fibroblast growth factor receptor type 2 and correlation with CTNNB1 genotype in adrenocortical carcinoma.

BMC Res Notes 2020 Jun 10;13(1):282. Epub 2020 Jun 10.

Division for Specific Endocrinology, Medical Faculty, University Hospital Duesseldorf, Moorenstr 5, 40225, Düsseldorf, Germany.

Objective: Fibroblast growth factor receptor (FGFR) 2 regulates the development of the adrenal gland in mice. In addition, FGFR2-mediated signalling has been shown to prevent apoptosis and to enhance proliferation in adrenocortical precursor cells. The activation of the Wingless/Int-1 (WNT)/beta catenin pathway as a key mechanism of adrenocortical tumourigenesis has been linked to FGFR2 signalling in other cell types. Read More

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http://dx.doi.org/10.1186/s13104-020-05110-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288682PMC

CaXyn30B from the solventogenic bacterium Clostridium acetobutylicum is a glucuronic acid-dependent endoxylanase.

BMC Res Notes 2020 Jun 10;13(1):281. Epub 2020 Jun 10.

Institute for Microbial and Biochemical Technology, Forest Products Laboratory, USDA Forest Service, One Gifford Pinchot Drive, Madison, WI, 53726, USA.

Objective: We previously described the structure and activity of a glycoside hydrolase family 30 subfamily 8 (GH30-8) endoxylanase, CaXyn30A, from Clostridium acetobutylicum which exhibited novel glucuronic acid (GA)-independent activity. Immediately downstream from CaXyn30A is encoded another GH30-8 enzyme, CaXyn30B. While CaXyn30A deviated substantially in the highly conserved β7-α7 and β8-α8 loop regions of the catalytic cleft which are responsible for GA-dependence, CaXyn30B maintains these conserved subfamily 8 amino acid residues thus predicting canonical GA-dependent activity. Read More

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http://dx.doi.org/10.1186/s13104-020-05091-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285738PMC

Draft genome sequence of antimicrobial producing Paenibacillus alvei strain MP1 reveals putative novel antimicrobials.

BMC Res Notes 2020 Jun 9;13(1):280. Epub 2020 Jun 9.

Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, G. Narutowicza Street 11/12, 80-233, Gdańsk, Poland.

Objective: A Paenibacillus strain isolated in previous research exhibited antimicrobial activity against relevant human pathogens including Staphylococcus aureus and Listeria monocytogenes. In this study, the genome of the aforementioned strain, designated as MP1, was shotgun sequenced. The draft genome of strain MP1 was subject to multiple genomic analyses to taxonomically characterize it and identify the genes potentially responsible for its antimicrobial activity. Read More

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http://dx.doi.org/10.1186/s13104-020-05124-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285544PMC

The relationship between health life style and spermogram Indicators among infertile men: preliminary data.

BMC Res Notes 2020 Jun 9;13(1):278. Epub 2020 Jun 9.

School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.

Objective: Inappropriate life style has destructive effects on sperm quality and, male fertility, so that lifestyle modification may improve spermogram indexes preliminary data. This study aimed to determine the relationship between health life style and spermogram Indicators among infertile men. This analytical descriptive cross-sectional study was conducted on 199 infertile men. Read More

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http://dx.doi.org/10.1186/s13104-020-05102-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285520PMC

Are patients on oral anticoagulation therapy aware of its effects? A cross-sectional study from Karachi, Pakistan.

BMC Res Notes 2020 Jun 9;13(1):279. Epub 2020 Jun 9.

John H Stroger Jr. Hospital of Cook County, Chicago, IL, USA.

Objective: Oral anticoagulants are one of the most frequently used medications. However, these drugs have a range of side effects including potential life-threatening complications. Little is known regarding the awareness of its side effect profile amongst the patients in Pakistan. Read More

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http://dx.doi.org/10.1186/s13104-020-05119-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285618PMC

Genotype distribution of methicillin-susceptible Staphylococcus aureus clinical isolates in Iran: high multiresistant clonal complex 8.

BMC Res Notes 2020 Jun 8;13(1):277. Epub 2020 Jun 8.

Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objective: Compared to methicillin-resistant Staphylococcus aureus (MRSA), there have been few studies focused on the molecular characterization of methicillin-susceptible Staphylococcus aureus (MSSA). In this cross-sectional study, 85 MSSA isolates were characterized by antimicrobial susceptibility testing, virulence genes analysis, accessory gene regulator (agr) typing, and S. aureus protein A locus (spa) typing. Read More

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http://dx.doi.org/10.1186/s13104-020-05127-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282160PMC